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Conserved domains on  [gi|197333715|ref|NP_776185|]
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uncharacterized protein C3orf38 [Homo sapiens]

Protein Classification

DUF4518 domain-containing protein( domain architecture ID 10633223)

DUF4518 domain-containing protein similar to Homo sapiens protein C3orf38

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
DUF4518 pfam15008
Domain of unknown function (DUF4518); The precise function of this protein family is unknown ...
6-278 5.51e-141

Domain of unknown function (DUF4518); The precise function of this protein family is unknown but it is thought to be involved in apoptosis regulation.


:

Pssm-ID: 464440  Cd Length: 263  Bit Score: 399.31  E-value: 5.51e-141
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 197333715    6 LSFSEMEGCRNLLGLLDNDEIMALCDTVTNRLVQPQDRQDAVHAILAYSQSAEELLRRRKVHREVIFKYLATQGIVIPPA 85
Cdd:pfam15008   1 LSEKEKKGLRDLLGLLETDDLLALADTVTNRVIKVENREEAIDAILLYSQDAEELLKRKKITREVLFKYLASKGVIVPPD 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 197333715   86 TEKHNLIQHAKDYWQKQPQLKlkeTPEPVTKTEDIHLFQQQVKEDKKAEKVDFRRLGEEFCHWFFGLLNSQNpflgppqd 165
Cdd:pfam15008  81 SEKADLIERVLQLWGSQLQAI---AVQNTTPTISSQNNAENPSPPKGLEQYPIHLLALQFCEWFFELLNSQN-------- 149
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 197333715  166 EWGPQHFWHDVKLRFY-YNTSEQNVMDYHGAEIVSLRLLSLVKEEFLFLSPNLDSHGLKCASSPHGLVMVGVAGTVHRGN 244
Cdd:pfam15008 150 DWGPQHFWSDAKLKLTiSNSSGQQVEECEGAEEVSLRLLSLVKEERLFFNPNLTHDGVKGRMDPHGLVLVLVCGTLHRDN 229
                         250       260       270
                  ....*....|....*....|....*....|....
gi 197333715  245 TCLGIFEQIFGLIRCPFVENTWKIKFINLKIMGE 278
Cdd:pfam15008 230 RCLGIFEQIFGLIRDPLADNNWKIKFVKLKIKSQ 263
 
Name Accession Description Interval E-value
DUF4518 pfam15008
Domain of unknown function (DUF4518); The precise function of this protein family is unknown ...
6-278 5.51e-141

Domain of unknown function (DUF4518); The precise function of this protein family is unknown but it is thought to be involved in apoptosis regulation.


Pssm-ID: 464440  Cd Length: 263  Bit Score: 399.31  E-value: 5.51e-141
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 197333715    6 LSFSEMEGCRNLLGLLDNDEIMALCDTVTNRLVQPQDRQDAVHAILAYSQSAEELLRRRKVHREVIFKYLATQGIVIPPA 85
Cdd:pfam15008   1 LSEKEKKGLRDLLGLLETDDLLALADTVTNRVIKVENREEAIDAILLYSQDAEELLKRKKITREVLFKYLASKGVIVPPD 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 197333715   86 TEKHNLIQHAKDYWQKQPQLKlkeTPEPVTKTEDIHLFQQQVKEDKKAEKVDFRRLGEEFCHWFFGLLNSQNpflgppqd 165
Cdd:pfam15008  81 SEKADLIERVLQLWGSQLQAI---AVQNTTPTISSQNNAENPSPPKGLEQYPIHLLALQFCEWFFELLNSQN-------- 149
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 197333715  166 EWGPQHFWHDVKLRFY-YNTSEQNVMDYHGAEIVSLRLLSLVKEEFLFLSPNLDSHGLKCASSPHGLVMVGVAGTVHRGN 244
Cdd:pfam15008 150 DWGPQHFWSDAKLKLTiSNSSGQQVEECEGAEEVSLRLLSLVKEERLFFNPNLTHDGVKGRMDPHGLVLVLVCGTLHRDN 229
                         250       260       270
                  ....*....|....*....|....*....|....
gi 197333715  245 TCLGIFEQIFGLIRCPFVENTWKIKFINLKIMGE 278
Cdd:pfam15008 230 RCLGIFEQIFGLIRDPLADNNWKIKFVKLKIKSQ 263
 
Name Accession Description Interval E-value
DUF4518 pfam15008
Domain of unknown function (DUF4518); The precise function of this protein family is unknown ...
6-278 5.51e-141

Domain of unknown function (DUF4518); The precise function of this protein family is unknown but it is thought to be involved in apoptosis regulation.


Pssm-ID: 464440  Cd Length: 263  Bit Score: 399.31  E-value: 5.51e-141
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 197333715    6 LSFSEMEGCRNLLGLLDNDEIMALCDTVTNRLVQPQDRQDAVHAILAYSQSAEELLRRRKVHREVIFKYLATQGIVIPPA 85
Cdd:pfam15008   1 LSEKEKKGLRDLLGLLETDDLLALADTVTNRVIKVENREEAIDAILLYSQDAEELLKRKKITREVLFKYLASKGVIVPPD 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 197333715   86 TEKHNLIQHAKDYWQKQPQLKlkeTPEPVTKTEDIHLFQQQVKEDKKAEKVDFRRLGEEFCHWFFGLLNSQNpflgppqd 165
Cdd:pfam15008  81 SEKADLIERVLQLWGSQLQAI---AVQNTTPTISSQNNAENPSPPKGLEQYPIHLLALQFCEWFFELLNSQN-------- 149
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 197333715  166 EWGPQHFWHDVKLRFY-YNTSEQNVMDYHGAEIVSLRLLSLVKEEFLFLSPNLDSHGLKCASSPHGLVMVGVAGTVHRGN 244
Cdd:pfam15008 150 DWGPQHFWSDAKLKLTiSNSSGQQVEECEGAEEVSLRLLSLVKEERLFFNPNLTHDGVKGRMDPHGLVLVLVCGTLHRDN 229
                         250       260       270
                  ....*....|....*....|....*....|....
gi 197333715  245 TCLGIFEQIFGLIRCPFVENTWKIKFINLKIMGE 278
Cdd:pfam15008 230 RCLGIFEQIFGLIRDPLADNNWKIKFVKLKIKSQ 263
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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