NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|27883860|ref|NP_777366|]
View 

zygote arrest protein 1 isoform 1 [Mus musculus]

Protein Classification

3CxxC-type zinc finger protein( domain architecture ID 10616235)

3CxxC-type zinc finger protein similar to Homo sapiens receptor-transporting protein 1 (RTP1) that specifically promotes functional cell surface expression of olfactory receptors, but not of other GPCRs

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
zf-3CxxC pfam13695
Zinc-binding domain; This is a family with several pairs of CxxC motifs possibly representing ...
 264-346 4.52e-10

Zinc-binding domain; This is a family with several pairs of CxxC motifs possibly representing a multiple zinc-binding region. Only one pair of cysteines is associated with a highly conserved histidine residue.


:

Pssm-ID: 463958  Cd Length: 96  Bit Score: 55.89  E-value: 4.52e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27883860   264 YGYYHCKDCKIRWESAYVWCV----------QGTSKVYFKQFCRVCEKSYNP----YRVEDITCQSCKRTRCACPVRLRh 329
Cdd:pfam13695   3 YGRFRCSSCSRKWTSAKVWITirmyldppgnGTYNARVYGQRCKKCKRLERPeldeEEVERVLYRLKKKIEKPCYGEKT- 81

                          90
                  ....*....|....*..
gi 27883860   330 vdpKRPHRQDLCGRCKD 346
Cdd:pfam13695  82 ---TGPHERDLCEGCKL 95
PRK07764 super family cl35613
DNA polymerase III subunits gamma and tau; Validated
 148-251 3.97e-04

DNA polymerase III subunits gamma and tau; Validated


The actual alignment was detected with superfamily member PRK07764:

Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 42.28  E-value: 3.97e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27883860  148 VAGGRQTPTKGEGSPASSGTREPEPREVAARKAVPQPRSEEGDVQAAGQAGWEQQPPPEdrnSVAAMQSEPGSEEPCPAA 227
Cdd:PRK07764 386 GVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSP---AGNAPAGGAPSPPPAAAP 462

                         90       100
                 ....*....|....*....|....
gi 27883860  228 EMAQDPGDSDAPRDQASPQSTEQD 251
Cdd:PRK07764 463 SAQPAPAPAAAPEPTAAPAPAPPA 486
 
Name Accession Description Interval E-value
zf-3CxxC pfam13695
Zinc-binding domain; This is a family with several pairs of CxxC motifs possibly representing ...
 264-346 4.52e-10

Zinc-binding domain; This is a family with several pairs of CxxC motifs possibly representing a multiple zinc-binding region. Only one pair of cysteines is associated with a highly conserved histidine residue.


Pssm-ID: 463958  Cd Length: 96  Bit Score: 55.89  E-value: 4.52e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27883860   264 YGYYHCKDCKIRWESAYVWCV----------QGTSKVYFKQFCRVCEKSYNP----YRVEDITCQSCKRTRCACPVRLRh 329
Cdd:pfam13695   3 YGRFRCSSCSRKWTSAKVWITirmyldppgnGTYNARVYGQRCKKCKRLERPeldeEEVERVLYRLKKKIEKPCYGEKT- 81

                          90
                  ....*....|....*..
gi 27883860   330 vdpKRPHRQDLCGRCKD 346
Cdd:pfam13695  82 ---TGPHERDLCEGCKL 95
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 148-251 3.97e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 42.28  E-value: 3.97e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27883860  148 VAGGRQTPTKGEGSPASSGTREPEPREVAARKAVPQPRSEEGDVQAAGQAGWEQQPPPEdrnSVAAMQSEPGSEEPCPAA 227
Cdd:PRK07764 386 GVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSP---AGNAPAGGAPSPPPAAAP 462

                         90       100
                 ....*....|....*....|....
gi 27883860  228 EMAQDPGDSDAPRDQASPQSTEQD 251
Cdd:PRK07764 463 SAQPAPAPAAAPEPTAAPAPAPPA 486
 
Name Accession Description Interval E-value
zf-3CxxC pfam13695
Zinc-binding domain; This is a family with several pairs of CxxC motifs possibly representing ...
 264-346 4.52e-10

Zinc-binding domain; This is a family with several pairs of CxxC motifs possibly representing a multiple zinc-binding region. Only one pair of cysteines is associated with a highly conserved histidine residue.


Pssm-ID: 463958  Cd Length: 96  Bit Score: 55.89  E-value: 4.52e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27883860   264 YGYYHCKDCKIRWESAYVWCV----------QGTSKVYFKQFCRVCEKSYNP----YRVEDITCQSCKRTRCACPVRLRh 329
Cdd:pfam13695   3 YGRFRCSSCSRKWTSAKVWITirmyldppgnGTYNARVYGQRCKKCKRLERPeldeEEVERVLYRLKKKIEKPCYGEKT- 81

                          90
                  ....*....|....*..
gi 27883860   330 vdpKRPHRQDLCGRCKD 346
Cdd:pfam13695  82 ---TGPHERDLCEGCKL 95
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 148-251 3.97e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 42.28  E-value: 3.97e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27883860  148 VAGGRQTPTKGEGSPASSGTREPEPREVAARKAVPQPRSEEGDVQAAGQAGWEQQPPPEdrnSVAAMQSEPGSEEPCPAA 227
Cdd:PRK07764 386 GVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSP---AGNAPAGGAPSPPPAAAP 462

                         90       100
                 ....*....|....*....|....
gi 27883860  228 EMAQDPGDSDAPRDQASPQSTEQD 251
Cdd:PRK07764 463 SAQPAPAPAAAPEPTAAPAPAPPA 486
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 149-256 1.89e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 40.35  E-value: 1.89e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27883860  149 AGGRQTPTKGEGSPASSGTREPEPR--EVAARKAVPQPRSEEGDVQAAGQAGWEQQPPPEDRNSVAAMQSEPGSEEPCPA 226
Cdd:PRK07764 404 AAPAAAPAPAAAAPAAAAAPAPAAApqPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQPAPAPAAAPEPTAAPAPA 483

                         90       100       110
                 ....*....|....*....|....*....|
gi 27883860  227 AEMAQDPGDSDAPRDQASPQSTEQDKERLR 256
Cdd:PRK07764 484 PPAAPAPAAAPAAPAAPAAPAGADDAATLR 513
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 67-254 1.89e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 40.35  E-value: 1.89e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27883860   67 GPRSVSSRDAAVQVNPRRDASVQCSLGRRTLQPAGCRASPDARSGSCQPRGHAGAGRSPRSWQTVAPFSSVTfcglsssl 146
Cdd:PRK07764 612 AARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPP-------- 683

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27883860  147 EVAGGRQTPTKGEGSPASSGTREPEPREVAARKAVPQPRSEEGDVQAAGQAGWEQQPPPEDRNSVAAMQSEPGSEEPCPA 226
Cdd:PRK07764 684 APAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPA 763

                        170       180
                 ....*....|....*....|....*...
gi 27883860  227 AEMAQDPGDSDAPRDQASPQSTEQDKER 254
Cdd:PRK07764 764 PAPAAAPAAAPPPSPPSEEEEMAEDDAP 791
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 149-250 3.07e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 39.58  E-value: 3.07e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27883860  149 AGGRQTPTKGEGSPASSGTREPEPRevAARKAVPQPRSEEGDVQAAGQAGWEQQPPPEDRNSvAAMQSEPGSEEPcPAAE 228
Cdd:PRK07764 402 AAAAPAAAPAPAAAAPAAAAAPAPA--AAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAA-PSAQPAPAPAAA-PEPT 477

                         90       100
                 ....*....|....*....|..
gi 27883860  229 MAQDPGDSDAPRDQASPQSTEQ 250
Cdd:PRK07764 478 AAPAPAPPAAPAPAAAPAAPAA 499
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 103-246 7.98e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 38.43  E-value: 7.98e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 27883860  103 RASPDARSGSCQPRGHAGAGRSPRSWQTVAPFssvtfcGLSSSLEVAGGRQTPTKGEGSPASSGTREP--EPREVAARKA 180
Cdd:PRK07764 663 SDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPA------GAAPAQPAPAPAATPPAGQADDPAAQPPQAaqGASAPSPAAD 736

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 27883860  181 VPQPRSEEGDVQAAGQAGWEQQPPPEDRNSVAAMQSEPGSEEPCPAAEMAQDPGDSDAPRDQASPQ 246
Cdd:PRK07764 737 DPVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEEEEMAEDDAPSMDDEDRRDAE 802
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH