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Conserved domains on  [gi|148922949|ref|NP_783641|]
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complement component receptor 1-like protein precursor [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PHA02927 super family cl33700
secreted complement-binding protein; Provisional
 35-287 5.73e-39

secreted complement-binding protein; Provisional


The actual alignment was detected with superfamily member PHA02927:

Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 143.64  E-value: 5.73e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148922949  35 CNVPewlpfARPTNLT--------DDFEFPIGTYLNYECRPGYSGRPFSIICLK--NSVWTsAKDKCKRKSCRNPPDPVN 104
Cdd:PHA02927  21 CTIP-----SRPINMKfknsvetdANANYNIGDTIEYLCLPGYRKQKMGPIYAKctGTGWT-LFNQCIKRRCPSPRDIDN 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148922949 105 GMAHvIKDIQFRSQIKYSCPKGYRLIGSSSATCII-SGNTVIWDNKTPVCDRIICGLPPTIANGDFTSISrEYFHYGSVV 183
Cdd:PHA02927  95 GQLD-IGGVDFGSSITYSCNSGYQLIGESKSYCELgSTGSMVWNPEAPICESVKCQSPPSISNGRHNGYE-DFYTDGSVV 172

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148922949 184 TYHCNLGsrgkkvFELVGEPSIYCTSkddqvGIWSGPaPQCIIPnKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFG 263
Cdd:PHA02927 173 TYSCNSG------YSLIGNSGVLCSG-----GEWSDP-PTCQIV-KCPHPTISNGYLSSGFKRSYSYNDNVDFKCKYGYK 239

                        250       260
                 ....*....|....*....|....
gi 148922949 264 MKGPSHVKCQALNKWEPELPSCSR 287
Cdd:PHA02927 240 LSGSSSSTCSPGNTWQPELPKCVR 263
PHA02927 super family cl33700
secreted complement-binding protein; Provisional
 284-541 1.87e-24

secreted complement-binding protein; Provisional


The actual alignment was detected with superfamily member PHA02927:

Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 102.81  E-value: 1.87e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148922949 284 SCSRVCQPPPDVLHAERTQRDKD-NFSPGQEVFYSCEPGYDLR--GSTYLHCTPQGdWSpAAPRCEVKSC----DDFLGQ 356
Cdd:PHA02927  19 SCCTIPSRPINMKFKNSVETDANaNYNIGDTIEYLCLPGYRKQkmGPIYAKCTGTG-WT-LFNQCIKRRCpsprDIDNGQ 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148922949 357 LPNGHVLFplnlqlGAKVDFVCDEGFQLKGSSASYCVLAGMESL-WNSSVPVCERKSCETPPVPVNGMVHVITDIHV-GS 434
Cdd:PHA02927  97 LDIGGVDF------GSSITYSCNSGYQLIGESKSYCELGSTGSMvWNPEAPICESVKCQSPPSISNGRHNGYEDFYTdGS 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148922949 435 RINYSCTTGHRLIGHSSAECilSGntAHWSmKPPICQQIFCPNpPAILNGRHTGTPLGDIPYGKEVSYTCDphpdrgMTF 514
Cdd:PHA02927 171 VVTYSCNSGYSLIGNSGVLC--SG--GEWS-DPPTCQIVKCPH-PTISNGYLSSGFKRSYSYNDNVDFKCK------YGY 238

                        250       260
                 ....*....|....*....|....*..
gi 148922949 515 NLIGESTirRTSEPhGNgVWSSPAPRC 541
Cdd:PHA02927 239 KLSGSSS--STCSP-GN-TWQPELPKC 261
 
Name Accession Description Interval E-value
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 35-287 5.73e-39

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 143.64  E-value: 5.73e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148922949  35 CNVPewlpfARPTNLT--------DDFEFPIGTYLNYECRPGYSGRPFSIICLK--NSVWTsAKDKCKRKSCRNPPDPVN 104
Cdd:PHA02927  21 CTIP-----SRPINMKfknsvetdANANYNIGDTIEYLCLPGYRKQKMGPIYAKctGTGWT-LFNQCIKRRCPSPRDIDN 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148922949 105 GMAHvIKDIQFRSQIKYSCPKGYRLIGSSSATCII-SGNTVIWDNKTPVCDRIICGLPPTIANGDFTSISrEYFHYGSVV 183
Cdd:PHA02927  95 GQLD-IGGVDFGSSITYSCNSGYQLIGESKSYCELgSTGSMVWNPEAPICESVKCQSPPSISNGRHNGYE-DFYTDGSVV 172

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148922949 184 TYHCNLGsrgkkvFELVGEPSIYCTSkddqvGIWSGPaPQCIIPnKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFG 263
Cdd:PHA02927 173 TYSCNSG------YSLIGNSGVLCSG-----GEWSDP-PTCQIV-KCPHPTISNGYLSSGFKRSYSYNDNVDFKCKYGYK 239

                        250       260
                 ....*....|....*....|....
gi 148922949 264 MKGPSHVKCQALNKWEPELPSCSR 287
Cdd:PHA02927 240 LSGSSSSTCSPGNTWQPELPKCVR 263
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 284-541 1.87e-24

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 102.81  E-value: 1.87e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148922949 284 SCSRVCQPPPDVLHAERTQRDKD-NFSPGQEVFYSCEPGYDLR--GSTYLHCTPQGdWSpAAPRCEVKSC----DDFLGQ 356
Cdd:PHA02927  19 SCCTIPSRPINMKFKNSVETDANaNYNIGDTIEYLCLPGYRKQkmGPIYAKCTGTG-WT-LFNQCIKRRCpsprDIDNGQ 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148922949 357 LPNGHVLFplnlqlGAKVDFVCDEGFQLKGSSASYCVLAGMESL-WNSSVPVCERKSCETPPVPVNGMVHVITDIHV-GS 434
Cdd:PHA02927  97 LDIGGVDF------GSSITYSCNSGYQLIGESKSYCELGSTGSMvWNPEAPICESVKCQSPPSISNGRHNGYEDFYTdGS 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148922949 435 RINYSCTTGHRLIGHSSAECilSGntAHWSmKPPICQQIFCPNpPAILNGRHTGTPLGDIPYGKEVSYTCDphpdrgMTF 514
Cdd:PHA02927 171 VVTYSCNSGYSLIGNSGVLC--SG--GEWS-DPPTCQIVKCPH-PTISNGYLSSGFKRSYSYNDNVDFKCK------YGY 238

                        250       260
                 ....*....|....*....|....*..
gi 148922949 515 NLIGESTirRTSEPhGNgVWSSPAPRC 541
Cdd:PHA02927 239 KLSGSSS--STCSP-GN-TWQPELPKC 261
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 289-346 6.90e-13

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 63.25  E-value: 6.90e-13
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 148922949 289 CQPPPDVLHAERTQRdKDNFSPGQEVFYSCEPGYDLRGSTYLHCTPQGDWSPAAPRCE 346
Cdd:cd00033    1 CPPPPVPENGTVTGS-KGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 289-345 1.67e-11

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 59.46  E-value: 1.67e-11
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 148922949   289 CQPPPDVLHAERTQRdKDNFSPGQEVFYSCEPGYDLRGSTYLHCTPQGDWSPAAPRC 345
Cdd:smart00032   1 CPPPPDIENGTVTSS-SGTYSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 158-225 1.84e-11

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 59.40  E-value: 1.84e-11
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 148922949 158 CGLPPTIANGDFTSiSREYFHYGSVVTYHCNLGsrgkkvFELVGEPSIYCTSKddqvGIWSGPAPQCI 225
Cdd:cd00033    1 CPPPPVPENGTVTG-SKGSYSYGSTVTYSCNEG------YTLVGSSTITCTEN----GGWSPPPPTCE 57
Sushi pfam00084
Sushi repeat (SCR repeat);
289-345 4.47e-11

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 58.28  E-value: 4.47e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 148922949  289 CQPPPDVLHAERTQRdKDNFSPGQEVFYSCEPGYDLRGSTYLHCTPQGDWSPAAPRC 345
Cdd:pfam00084   1 CPPPPDIPNGKVSAT-KNEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 158-224 5.80e-10

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 55.23  E-value: 5.80e-10
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 148922949   158 CGLPPTIANGDFTSiSREYFHYGSVVTYHCNLGsrgkkvFELVGEPSIYCTSKddqvGIWSGPAPQC 224
Cdd:smart00032   1 CPPPPDIENGTVTS-SSGTYSYGDTVTYSCDPG------YTLIGSSTITCLEN----GTWSPPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
230-285 2.30e-08

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 50.58  E-value: 2.30e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 148922949  230 CTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFGMKGPSHVKCQALNKWEPELPSC 285
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
 
Name Accession Description Interval E-value
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 35-287 5.73e-39

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 143.64  E-value: 5.73e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148922949  35 CNVPewlpfARPTNLT--------DDFEFPIGTYLNYECRPGYSGRPFSIICLK--NSVWTsAKDKCKRKSCRNPPDPVN 104
Cdd:PHA02927  21 CTIP-----SRPINMKfknsvetdANANYNIGDTIEYLCLPGYRKQKMGPIYAKctGTGWT-LFNQCIKRRCPSPRDIDN 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148922949 105 GMAHvIKDIQFRSQIKYSCPKGYRLIGSSSATCII-SGNTVIWDNKTPVCDRIICGLPPTIANGDFTSISrEYFHYGSVV 183
Cdd:PHA02927  95 GQLD-IGGVDFGSSITYSCNSGYQLIGESKSYCELgSTGSMVWNPEAPICESVKCQSPPSISNGRHNGYE-DFYTDGSVV 172

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148922949 184 TYHCNLGsrgkkvFELVGEPSIYCTSkddqvGIWSGPaPQCIIPnKCTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFG 263
Cdd:PHA02927 173 TYSCNSG------YSLIGNSGVLCSG-----GEWSDP-PTCQIV-KCPHPTISNGYLSSGFKRSYSYNDNVDFKCKYGYK 239

                        250       260
                 ....*....|....*....|....
gi 148922949 264 MKGPSHVKCQALNKWEPELPSCSR 287
Cdd:PHA02927 240 LSGSSSSTCSPGNTWQPELPKCVR 263
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 284-541 1.87e-24

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 102.81  E-value: 1.87e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148922949 284 SCSRVCQPPPDVLHAERTQRDKD-NFSPGQEVFYSCEPGYDLR--GSTYLHCTPQGdWSpAAPRCEVKSC----DDFLGQ 356
Cdd:PHA02927  19 SCCTIPSRPINMKFKNSVETDANaNYNIGDTIEYLCLPGYRKQkmGPIYAKCTGTG-WT-LFNQCIKRRCpsprDIDNGQ 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148922949 357 LPNGHVLFplnlqlGAKVDFVCDEGFQLKGSSASYCVLAGMESL-WNSSVPVCERKSCETPPVPVNGMVHVITDIHV-GS 434
Cdd:PHA02927  97 LDIGGVDF------GSSITYSCNSGYQLIGESKSYCELGSTGSMvWNPEAPICESVKCQSPPSISNGRHNGYEDFYTdGS 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148922949 435 RINYSCTTGHRLIGHSSAECilSGntAHWSmKPPICQQIFCPNpPAILNGRHTGTPLGDIPYGKEVSYTCDphpdrgMTF 514
Cdd:PHA02927 171 VVTYSCNSGYSLIGNSGVLC--SG--GEWS-DPPTCQIVKCPH-PTISNGYLSSGFKRSYSYNDNVDFKCK------YGY 238

                        250       260
                 ....*....|....*....|....*..
gi 148922949 515 NLIGESTirRTSEPhGNgVWSSPAPRC 541
Cdd:PHA02927 239 KLSGSSS--STCSP-GN-TWQPELPKC 261
PHA02639 PHA02639
EEV host range protein; Provisional
 92-308 8.65e-21

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 92.80  E-value: 8.65e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148922949  92 KRKSCRNPPDPVNG-MAHVIKDIQFRSQIKYSCPKGYRLIGSSSATCIISGNTVIWDNKTPVCDRIICGLPPTIANGDFT 170
Cdd:PHA02639  18 KSIYCDKPDDISNGfITELMEKYEIGKLIEYTCNTDYALIGDRFRTCIKDKNNAIWSNKAPFCMLKECNDPPSIINGKIY 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148922949 171 SiSREYFHYGSVVTYHCNlGSRGKKvFELVGEPSIYCTskddQVGIWSGPAPQCIIPNkCTPPNVENGIL--VSDNRSlF 248
Cdd:PHA02639  98 N-KREMYKVGDEIYYVCN-EHKGVQ-YSLVGNEKITCI----QDKSWKPDPPICKMIN-CRFPALQNGYIngIPSNKK-F 168

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 148922949 249 SLNEVVEFRCQPGFGMKGPSHVKCQALNKWEPELPSCSRvCQPPPDVLHAERTQRDKDNF 308
Cdd:PHA02639 169 YYKTRVGFSCKSGFDLVGEKYSTCNINATWFPSIPTCVR-NKPIDDIIYLKPVDDNFDDL 227
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 367-543 2.66e-16

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 78.93  E-value: 2.66e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148922949 367 NLQLGAKVDFVCDEGF--QLKGSSASYCVLAGMeSLWNSsvpvCERKSCETPPVPVNGMVHvITDIHVGSRINYSCTTGH 444
Cdd:PHA02927  43 NYNIGDTIEYLCLPGYrkQKMGPIYAKCTGTGW-TLFNQ----CIKRRCPSPRDIDNGQLD-IGGVDFGSSITYSCNSGY 116

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148922949 445 RLIGHSSAECIL-SGNTAHWSMKPPICQQIFCPNPPAILNGRHTGTplgDIPY--GKEVSYTCDPhpdrgmTFNLIGEST 521
Cdd:PHA02927 117 QLIGESKSYCELgSTGSMVWNPEAPICESVKCQSPPSISNGRHNGY---EDFYtdGSVVTYSCNS------GYSLIGNSG 187

                        170       180
                 ....*....|....*....|..
gi 148922949 522 IRRTSephgnGVWSSPaPRCEL 543
Cdd:PHA02927 188 VLCSG-----GEWSDP-PTCQI 203
PHA02639 PHA02639
EEV host range protein; Provisional
 158-354 1.55e-14

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 74.32  E-value: 1.55e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148922949 158 CGLPPTIANGDFTSISREYfHYGSVVTYHCNLGsrgkkvFELVGEPSIYCTsKDDQVGIWSGPAPQCIIPNKCTPPNVEN 237
Cdd:PHA02639  22 CDKPDDISNGFITELMEKY-EIGKLIEYTCNTD------YALIGDRFRTCI-KDKNNAIWSNKAPFCMLKECNDPPSIIN 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148922949 238 GiLVSDNRSLFSLNEVVEFRCQPGFGMK----GPSHVKCQALNKWEPELPSCSRV-CQPPPdvlhaerTQRDKDNFSPGQ 312
Cdd:PHA02639  94 G-KIYNKREMYKVGDEIYYVCNEHKGVQyslvGNEKITCIQDKSWKPDPPICKMInCRFPA-------LQNGYINGIPSN 165

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 148922949 313 EVFY-------SCEPGYDLRGSTYLHCTPQGDWSPAAPRC-EVKSCDDFL 354
Cdd:PHA02639 166 KKFYyktrvgfSCKSGFDLVGEKYSTCNINATWFPSIPTCvRNKPIDDII 215
PHA02817 PHA02817
EEV Host range protein; Provisional
 153-287 1.73e-13

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 69.97  E-value: 1.73e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148922949 153 CDRIICGLPPTIANGDFTSISREYfHYGSVVTYHCNLGSRGKKvFELVGEPSIYCtSKDdqvGIWSGPAPQCIIPnKCTP 232
Cdd:PHA02817  19 CDLNKCCYPPSIKNGYIYNKKTEY-NIGSNVTFFCGNNTRGVR-YTLVGEKNIIC-EKD---GKWNKEFPVCKII-RCRF 91

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 148922949 233 PNVENGIL--VSDNRSLFSLNEvVEFRCQPGFGMKGPSHVKCQALNKWEPELPSCSR 287
Cdd:PHA02817  92 PALQNGFVngIPDSKKFYYESE-VSFSCKPGFVLIGTKYSVCGINSSWIPKVPICSR 147
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 289-346 6.90e-13

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 63.25  E-value: 6.90e-13
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 148922949 289 CQPPPDVLHAERTQRdKDNFSPGQEVFYSCEPGYDLRGSTYLHCTPQGDWSPAAPRCE 346
Cdd:cd00033    1 CPPPPVPENGTVTGS-KGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
PHA02639 PHA02639
EEV host range protein; Provisional
 369-541 2.57e-12

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 67.77  E-value: 2.57e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148922949 369 QLGAKVDFVCDEGFQLKGSSASYCVLAGMESLWNSSVPVCERKSCETPPVPVNGMVHVITDIH-VGSRINYSCT----TG 443
Cdd:PHA02639  41 EIGKLIEYTCNTDYALIGDRFRTCIKDKNNAIWSNKAPFCMLKECNDPPSIINGKIYNKREMYkVGDEIYYVCNehkgVQ 120

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148922949 444 HRLIGHSSAECIlsgNTAHWSMKPPICQQIFCpNPPAILNGRHTGTPLGDIPYGK-EVSYTCDPhpdrgmTFNLIGEsti 522
Cdd:PHA02639 121 YSLVGNEKITCI---QDKSWKPDPPICKMINC-RFPALQNGYINGIPSNKKFYYKtRVGFSCKS------GFDLVGE--- 187

                        170
                 ....*....|....*....
gi 148922949 523 rRTSEPHGNGVWSSPAPRC 541
Cdd:PHA02639 188 -KYSTCNINATWFPSIPTC 205
PHA02639 PHA02639
EEV host range protein; Provisional
 392-543 1.21e-11

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 65.84  E-value: 1.21e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148922949 392 CVLAGMESLWnssvpvcerksCETPPVPVNGMV-HVITDIHVGSRINYSCTTGHRLIGHSSAECILSGNTAHWSMKPPIC 470
Cdd:PHA02639  12 CYVHGVKSIY-----------CDKPDDISNGFItELMEKYEIGKLIEYTCNTDYALIGDRFRTCIKDKNNAIWSNKAPFC 80

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 148922949 471 QQIFCPNPPAILNGR-HTGTPLGDIpyGKEVSYTCDPHpdRGMTFNLIGESTIRRTSEPHgngvWSSPAPRCEL 543
Cdd:PHA02639  81 MLKECNDPPSIINGKiYNKREMYKV--GDEIYYVCNEH--KGVQYSLVGNEKITCIQDKS----WKPDPPICKM 146
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 289-345 1.67e-11

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 59.46  E-value: 1.67e-11
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 148922949   289 CQPPPDVLHAERTQRdKDNFSPGQEVFYSCEPGYDLRGSTYLHCTPQGDWSPAAPRC 345
Cdd:smart00032   1 CPPPPDIENGTVTSS-SGTYSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 158-225 1.84e-11

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 59.40  E-value: 1.84e-11
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 148922949 158 CGLPPTIANGDFTSiSREYFHYGSVVTYHCNLGsrgkkvFELVGEPSIYCTSKddqvGIWSGPAPQCI 225
Cdd:cd00033    1 CPPPPVPENGTVTG-SKGSYSYGSTVTYSCNEG------YTLVGSSTITCTEN----GGWSPPPPTCE 57
Sushi pfam00084
Sushi repeat (SCR repeat);
289-345 4.47e-11

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 58.28  E-value: 4.47e-11
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 148922949  289 CQPPPDVLHAERTQRdKDNFSPGQEVFYSCEPGYDLRGSTYLHCTPQGDWSPAAPRC 345
Cdd:pfam00084   1 CPPPPDIPNGKVSAT-KNEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
PHA02831 PHA02831
EEV host range protein; Provisional
 118-287 7.56e-11

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 63.09  E-value: 7.56e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148922949 118 QIKYSCPKGYrliGSSSATCiisgNTVIWDNKTPVCDRIICGLPPTIANGDFTSiSREYFHYGSVVTYHCNLGSRGKkvF 197
Cdd:PHA02831  45 NLEYKCNNNF---DKVFVTC----NNGSWSTKNMCIGKRNCKDPVTILNGYIKN-KKDQYSFGDSVTYACKVNKLEK--Y 114

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148922949 198 ELVGEPSIYCTSKDdqvgiWSGPAPQCIIPnKCTPPNVENGILVSDNRSlFSLNEVVEFRCQPGFGMKGPSHVKCQALNK 277
Cdd:PHA02831 115 SIVGNETVKCINKQ-----WVPKYPVCKLI-RCKYPALQNGFLNVFEKK-FYYGDIVNFKCKKGFILLGSSVSTCDINSI 187

                        170
                 ....*....|
gi 148922949 278 WEPELPSCSR 287
Cdd:PHA02831 188 WYPGIPKCVK 197
PHA02639 PHA02639
EEV host range protein; Provisional
 35-225 8.94e-11

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 63.14  E-value: 8.94e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148922949  35 CNVPEWLPFARPTNLTDDFEfpIGTYLNYECRPGYS--GRPFSIiCLK---NSVWTSAKDKCKRKSCRNPPDPVNGMAHV 109
Cdd:PHA02639  22 CDKPDDISNGFITELMEKYE--IGKLIEYTCNTDYAliGDRFRT-CIKdknNAIWSNKAPFCMLKECNDPPSIINGKIYN 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148922949 110 IKDI-QFRSQIKYSCP--KG--YRLIGSSSATCIISGNtviWDNKTPVCDRIICGLpPTIANGDFTSI-SREYFHYGSVV 183
Cdd:PHA02639  99 KREMyKVGDEIYYVCNehKGvqYSLVGNEKITCIQDKS---WKPDPPICKMINCRF-PALQNGYINGIpSNKKFYYKTRV 174

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 148922949 184 TYHCNLGsrgkkvFELVGEPSIYCTSKddqvGIWSGPAPQCI 225
Cdd:PHA02639 175 GFSCKSG------FDLVGEKYSTCNIN----ATWFPSIPTCV 206
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 158-224 5.80e-10

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 55.23  E-value: 5.80e-10
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 148922949   158 CGLPPTIANGDFTSiSREYFHYGSVVTYHCNLGsrgkkvFELVGEPSIYCTSKddqvGIWSGPAPQC 224
Cdd:smart00032   1 CPPPPDIENGTVTS-SSGTYSYGDTVTYSCDPG------YTLIGSSTITCLEN----GTWSPPPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 96-153 1.39e-09

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 54.01  E-value: 1.39e-09
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 148922949  96 CRNPPDPVNG-MAHVIKDIQFRSQIKYSCPKGYRLIGSSSATCIISGNtviWDNKTPVC 153
Cdd:cd00033    1 CPPPPVPENGtVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTENGG---WSPPPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 413-471 2.20e-09

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 53.62  E-value: 2.20e-09
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 148922949 413 CETPPVPVNG-MVHVITDIHVGSRINYSCTTGHRLIGHSSAECILSGntaHWSMKPPICQ 471
Cdd:cd00033    1 CPPPPVPENGtVTGSKGSYSYGSTVTYSCNEGYTLVGSSTITCTENG---GWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 96-153 2.95e-09

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 52.91  E-value: 2.95e-09
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 148922949    96 CRNPPDPVNGMAHVIKD-IQFRSQIKYSCPKGYRLIGSSSATCIISGNtviWDNKTPVC 153
Cdd:smart00032   1 CPPPPDIENGTVTSSSGtYSYGDTVTYSCDPGYTLIGSSTITCLENGT---WSPPPPTC 56
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 244-418 3.46e-09

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 58.56  E-value: 3.46e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148922949 244 NRSLFSLNEVVEFRCQpgfgmKGPSHVKCQALN---KWEPELPSCSRVCQPPPdvLHAERTQRDKDNFSPGQEVFYSCEP 320
Cdd:PHA02954  87 DKPLYEVNSTITLICK-----DETKYFRCEEKNgntSWNDTVTCPNAECQPLQ--LEHGSCQPVKEKYSFGEHITINCDV 159

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148922949 321 GYDLRGSTYLHCTPQgDWSpAAPRCEVKsCDdfLGQLPNGhVLFPLNLQLGAKVDFVCDEGFQLKGSSASYCVlagmESL 400
Cdd:PHA02954 160 GYEVIGASYISCTAN-SWN-VIPSCQQK-CD--IPSLSNG-LISGSTFSIGGVIHLSCKSGFTLTGSPSSTCI----DGK 229

                        170
                 ....*....|....*...
gi 148922949 401 WNSSVPVCERKSCETPPV 418
Cdd:PHA02954 230 WNPVLPICVRSNEEFDPV 247
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 231-285 5.85e-09

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 52.08  E-value: 5.85e-09
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 148922949 231 TPPNVENGILVSDNRSlFSLNEVVEFRCQPGFGMKGPSHVKCQALNKWEPELPSC 285
Cdd:cd00033    3 PPPVPENGTVTGSKGS-YSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 231-285 6.84e-09

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 52.14  E-value: 6.84e-09
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 148922949   231 TPPNVENGILVSDNRSlFSLNEVVEFRCQPGFGMKGPSHVKCQALNKWEPELPSC 285
Cdd:smart00032   3 PPPDIENGTVTSSSGT-YSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
PHA02831 PHA02831
EEV host range protein; Provisional
 251-412 6.86e-09

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 56.92  E-value: 6.86e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148922949 251 NEVVEFRCQPGFGmkgPSHVKCQALNKWEPELPSCSRVCQPPPDVLHAErTQRDKDNFSPGQEVFYSCEPG----YDLRG 326
Cdd:PHA02831  43 NENLEYKCNNNFD---KVFVTCNNGSWSTKNMCIGKRNCKDPVTILNGY-IKNKKDQYSFGDSVTYACKVNklekYSIVG 118

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148922949 327 STYLHCTpQGDWSPAAPRCEVKSCDdfLGQLPNGHV-LFPLNLQLGAKVDFVCDEGFQLKGSSASYCvlaGMESLWNSSV 405
Cdd:PHA02831 119 NETVKCI-NKQWVPKYPVCKLIRCK--YPALQNGFLnVFEKKFYYGDIVNFKCKKGFILLGSSVSTC---DINSIWYPGI 192


                 ....*..
gi 148922949 406 PVCERKS 412
Cdd:PHA02831 193 PKCVKDK 199
PHA02817 PHA02817
EEV Host range protein; Provisional
 289-410 9.38e-09

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 56.10  E-value: 9.38e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148922949 289 CQPPPDVLHAERTQRdKDNFSPGQEVFYSCEPG-----YDLRGSTYLHCTPQGDWSPAAPRCEVKSCDdfLGQLPNGHVL 363
Cdd:PHA02817  24 CCYPPSIKNGYIYNK-KTEYNIGSNVTFFCGNNtrgvrYTLVGEKNIICEKDGKWNKEFPVCKIIRCR--FPALQNGFVN 100

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 148922949 364 -FPLNLQL--GAKVDFVCDEGFQLKGSSASYCvlaGMESLWNSSVPVCER 410
Cdd:PHA02817 101 gIPDSKKFyyESEVSFSCKPGFVLIGTKYSVC---GINSSWIPKVPICSR 147
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 413-470 1.91e-08

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 50.60  E-value: 1.91e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*....
gi 148922949   413 CETPPVPVNGMVHVITD-IHVGSRINYSCTTGHRLIGHSSAECILSGNtahWSMKPPIC 470
Cdd:smart00032   1 CPPPPDIENGTVTSSSGtYSYGDTVTYSCDPGYTLIGSSTITCLENGT---WSPPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
230-285 2.30e-08

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 50.58  E-value: 2.30e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 148922949  230 CTPPNVENGILVSDNRSLFSLNEVVEFRCQPGFGMKGPSHVKCQALNKWEPELPSC 285
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
158-224 4.89e-08

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 49.81  E-value: 4.89e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 148922949  158 CGLPPTIANGDFTSiSREYFHYGSVVTYHCNLGsrgkkvFELVGEPSIYCTskddQVGIWSGPAPQC 224
Cdd:pfam00084   1 CPPPPDIPNGKVSA-TKNEYNYGASVSYECDPG------YRLVGSPTITCQ----EDGTWSPPFPEC 56
PHA02817 PHA02817
EEV Host range protein; Provisional
 224-345 1.16e-07

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 52.64  E-value: 1.16e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148922949 224 CIIPNKCTPPNVENGiLVSDNRSLFSLNEVVEFRCQPG-----FGMKGPSHVKCQALNKWEPELPSCSRV-CQPPPDVLH 297
Cdd:PHA02817  19 CDLNKCCYPPSIKNG-YIYNKKTEYNIGSNVTFFCGNNtrgvrYTLVGEKNIICEKDGKWNKEFPVCKIIrCRFPALQNG 97

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 148922949 298 AERTQRDKDNFSPGQEVFYSCEPGYDLRGSTYLHCTPQGDWSPAAPRC 345
Cdd:PHA02817  98 FVNGIPDSKKFYYESEVSFSCKPGFVLIGTKYSVCGINSSWIPKVPIC 145
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 475-542 2.42e-07

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 47.84  E-value: 2.42e-07
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 148922949 475 CPNPPAILNGRHTGTpLGDIPYGKEVSYTCDPHpdrgmtFNLIGESTIRRTSephgNGVWSSPAPRCE 542
Cdd:cd00033    1 CPPPPVPENGTVTGS-KGSYSYGSTVTYSCNEG------YTLVGSSTITCTE----NGGWSPPPPTCE 57
Sushi pfam00084
Sushi repeat (SCR repeat);
96-153 3.28e-07

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 47.11  E-value: 3.28e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 148922949   96 CRNPPDPVNGMAHVIKDI-QFRSQIKYSCPKGYRLIGSSSATCIISGNtviWDNKTPVC 153
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEyNYGASVSYECDPGYRLVGSPTITCQEDGT---WSPPFPEC 56
PHA02817 PHA02817
EEV Host range protein; Provisional
 76-244 4.82e-07

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 51.09  E-value: 4.82e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148922949  76 IICLKNSVWTSakdkCKRKSCRNPPDPVNGMAHVIKDIQFR-SQIKYSCPKG-----YRLIGSSSATCIISGNtviWDNK 149
Cdd:PHA02817   8 LILLCNKVYSL----CDLNKCCYPPSIKNGYIYNKKTEYNIgSNVTFFCGNNtrgvrYTLVGEKNIICEKDGK---WNKE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148922949 150 TPVCDRIICGLpPTIANGDFTSI-SREYFHYGSVVTYHCNLGsrgkkvFELVGEPSIYCTSKDDqvgiWSGPAPQCIIPN 228
Cdd:PHA02817  81 FPVCKIIRCRF-PALQNGFVNGIpDSKKFYYESEVSFSCKPG------FVLIGTKYSVCGINSS----WIPKVPICSRDN 149

                        170
                 ....*....|....*.
gi 148922949 229 KCTPPNVENGILVSDN 244
Cdd:PHA02817 150 ITYNKIYINKVNIDDN 165
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 475-541 4.37e-06

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 44.05  E-value: 4.37e-06
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 148922949   475 CPNPPAILNGRHTGTPlGDIPYGKEVSYTCDPHpdrgmtFNLIGESTIRRTSephgNGVWSSPAPRC 541
Cdd:smart00032   1 CPPPPDIENGTVTSSS-GTYSYGDTVTYSCDPG------YTLIGSSTITCLE----NGTWSPPPPTC 56
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 224-470 4.58e-06

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 48.93  E-value: 4.58e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148922949 224 CIIP----NKCTPPNVENGILVSDNRSlFSLNEVVEFRCQPGFGMKGPSHVkCQAlNKWEPELPsCSRVCQPPPDVlhae 299
Cdd:PHA02954  11 CVLPavvySTCTVPTMNNAKLTSTETS-FNDKQKVTFTCDSGYYSLDPNAV-CET-DKWKYENP-CKKMCTVSDYV---- 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148922949 300 rtqrdkdnfspgQEVFYscEPGYDLRGSTYLHCTPQGDWSpaapRCEVK----SCDDFLgQLPNGHVLfPLNLQ------ 369
Cdd:PHA02954  83 ------------SELYD--KPLYEVNSTITLICKDETKYF----RCEEKngntSWNDTV-TCPNAECQ-PLQLEhgscqp 142

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148922949 370 ------LGAKVDFVCDEGFQLKGSSASYCVlagmESLWNSsVPVCERKsCETPPVPvNGMVHVITdIHVGSRINYSCTTG 443
Cdd:PHA02954 143 vkekysFGEHITINCDVGYEVIGASYISCT----ANSWNV-IPSCQQK-CDIPSLS-NGLISGST-FSIGGVIHLSCKSG 214

                        250       260
                 ....*....|....*....|....*..
gi 148922949 444 HRLIGHSSAECIlsgnTAHWSMKPPIC 470
Cdd:PHA02954 215 FTLTGSPSSTCI----DGKWNPVLPIC 237
PHA02817 PHA02817
EEV Host range protein; Provisional
 408-519 7.49e-06

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 47.24  E-value: 7.49e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148922949 408 CERKSCETPPVPVNGMVH-VITDIHVGSRINYSCTTGHR-----LIGHSSAECILSGNtahWSMKPPICQQIFCpNPPAI 481
Cdd:PHA02817  19 CDLNKCCYPPSIKNGYIYnKKTEYNIGSNVTFFCGNNTRgvrytLVGEKNIICEKDGK---WNKEFPVCKIIRC-RFPAL 94

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 148922949 482 LNGRHTGTPLG-DIPYGKEVSYTCDPhpdrgmTFNLIGE 519
Cdd:PHA02817  95 QNGFVNGIPDSkKFYYESEVSFSCKP------GFVLIGT 127
PHA02817 PHA02817
EEV Host range protein; Provisional
 54-155 2.64e-05

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 45.70  E-value: 2.64e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148922949  54 EFPIGTYLNYECRPGYSGRPFS------IICLKNSVWTSAKDKCKRKSCRNPP---DPVNGMAHViKDIQFRSQIKYSCP 124
Cdd:PHA02817  41 EYNIGSNVTFFCGNNTRGVRYTlvgeknIICEKDGKWNKEFPVCKIIRCRFPAlqnGFVNGIPDS-KKFYYESEVSFSCK 119

                         90       100       110
                 ....*....|....*....|....*....|.
gi 148922949 125 KGYRLIGSSSATCIISGNtviWDNKTPVCDR 155
Cdd:PHA02817 120 PGFVLIGTKYSVCGINSS---WIPKVPICSR 147
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 352-409 2.66e-05

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 42.06  E-value: 2.66e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 148922949 352 DFLGQLPNGHVLFPL-NLQLGAKVDFVCDEGFQLKGSSASYCVLAGMeslWNSSVPVCE 409
Cdd:cd00033    2 PPPPVPENGTVTGSKgSYSYGSTVTYSCNEGYTLVGSSTITCTENGG---WSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 352-408 4.48e-05

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 41.36  E-value: 4.48e-05
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 148922949   352 DFLGQLPNGHVLFP-LNLQLGAKVDFVCDEGFQLKGSSASYCVLAGMeslWNSSVPVC 408
Cdd:smart00032   2 PPPPDIENGTVTSSsGTYSYGDTVTYSCDPGYTLIGSSTITCLENGT---WSPPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
475-541 4.61e-05

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 41.33  E-value: 4.61e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 148922949  475 CPNPPAILNGRHTGTpLGDIPYGKEVSYTCDPHpdrgmtFNLIGESTIRRTsephGNGVWSSPAPRC 541
Cdd:pfam00084   1 CPPPPDIPNGKVSAT-KNEYNYGASVSYECDPG------YRLVGSPTITCQ----EDGTWSPPFPEC 56
PHA02831 PHA02831
EEV host range protein; Provisional
 215-352 1.01e-04

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 44.21  E-value: 1.01e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148922949 215 GIWSgPAPQCIIPNKCTPP-NVENGiLVSDNRSLFSLNEVVEFRCQPG----FGMKGPSHVKCQAlNKWEPELPSCSRV- 288
Cdd:PHA02831  64 GSWS-TKNMCIGKRNCKDPvTILNG-YIKNKKDQYSFGDSVTYACKVNklekYSIVGNETVKCIN-KQWVPKYPVCKLIr 140

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 148922949 289 CQPPpdVLHAERTQRDKDNFSPGQEVFYSCEPGYDLRGSTYLHCTPQGDWSPAAPRCEVKSCDD 352
Cdd:PHA02831 141 CKYP--ALQNGFLNVFEKKFYYGDIVNFKCKKGFILLGSSVSTCDINSIWYPGIPKCVKDKVHN 202
Sushi pfam00084
Sushi repeat (SCR repeat);
35-91 1.27e-04

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 40.18  E-value: 1.27e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 148922949   35 CNVPEWLPFARPTNLTDdfEFPIGTYLNYECRPGY--SGRPfSIICLKNSVWTSAKDKC 91
Cdd:pfam00084   1 CPPPPDIPNGKVSATKN--EYNYGASVSYECDPGYrlVGSP-TITCQEDGTWSPPFPEC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 35-91 1.66e-04

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 39.82  E-value: 1.66e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 148922949    35 CNVPEWLPFARPTNLTDDFEFpiGTYLNYECRPGYSGR-PFSIICLKNSVWTSAKDKC 91
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSY--GDTVTYSCDPGYTLIgSSTITCLENGTWSPPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
357-408 1.77e-04

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 39.40  E-value: 1.77e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 148922949  357 LPNGHVLFPLN-LQLGAKVDFVCDEGFQLKGSSASYCVLAGMeslWNSSVPVC 408
Cdd:pfam00084   7 IPNGKVSATKNeYNYGASVSYECDPGYRLVGSPTITCQEDGT---WSPPFPEC 56
PHA02831 PHA02831
EEV host range protein; Provisional
 297-454 4.69e-04

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 42.29  E-value: 4.69e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148922949 297 HAERTQRDKDNFSpgqevfYSCEPGYDlrgSTYLHCTpQGDWSPAAPRCEVKSCDDFLGQLpNGHVLFPLN-LQLGAKVD 375
Cdd:PHA02831  35 YENKVYEENENLE------YKCNNNFD---KVFVTCN-NGSWSTKNMCIGKRNCKDPVTIL-NGYIKNKKDqYSFGDSVT 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148922949 376 FVCD----EGFQLKGSSASYCVlagmESLWNSSVPVCERKSCETPPVPvNGMVHVI-TDIHVGSRINYSCTTGHRLIGHS 450
Cdd:PHA02831 104 YACKvnklEKYSIVGNETVKCI----NKQWVPKYPVCKLIRCKYPALQ-NGFLNVFeKKFYYGDIVNFKCKKGFILLGSS 178


                 ....
gi 148922949 451 SAEC 454
Cdd:PHA02831 179 VSTC 182
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 54-92 1.47e-03

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 37.06  E-value: 1.47e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|
gi 148922949  54 EFPIGTYLNYECRPGYSGR-PFSIICLKNSVWTSAKDKCK 92
Cdd:cd00033   18 SYSYGSTVTYSCNEGYTLVgSSTITCTENGGWSPPPPTCE 57
PHA02817 PHA02817
EEV Host range protein; Provisional
 371-470 7.72e-03

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 38.38  E-value: 7.72e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 148922949 371 GAKVDFVCDEG-----FQLKGSSASYCVLAGMeslWNSSVPVCERKSCETPPVPvNGMVHVITD---IHVGSRINYSCTT 442
Cdd:PHA02817  45 GSNVTFFCGNNtrgvrYTLVGEKNIICEKDGK---WNKEFPVCKIIRCRFPALQ-NGFVNGIPDskkFYYESEVSFSCKP 120

                         90       100
                 ....*....|....*....|....*...
gi 148922949 443 GHRLIGHSSAECilsGNTAHWSMKPPIC 470
Cdd:PHA02817 121 GFVLIGTKYSVC---GINSSWIPKVPIC 145
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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