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neuronal PAS domain-containing protein 4 isoform 1 [Homo sapiens]
List of domain hits
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Name | Accession | Description | Interval | E-value | |||
bHLH-PAS_NPAS4_PASD10 | cd19697 | basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in neuronal PAS domain-containing ... |
2-57 | 3.49e-33 | |||
basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in neuronal PAS domain-containing protein 4 (NPAS4) and similar proteins; NPAS4, also termed neuronal Per-Arnt-Sim homology (PAS) factor 4, or neuronal PAS4, or Class E basic helix-loop-helix protein 79 (bHLHe79), or HLH-PAS transcription factor NXF, or PAS domain-containing protein 10 (PASD10), is a bHLH-PAS neuronal activity-dependent transcription factor which heterodimerizes with ARNT2 to regulate genes involved in inhibitory synapse formation. : Pssm-ID: 381540 Cd Length: 57 Bit Score: 121.64 E-value: 3.49e-33
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PAS_11 super family | cl37882 | PAS domain; This family includes the PAS-B domain of NCOA1 (Nuclear receptor coactivator 1), ... |
217-319 | 1.76e-10 | |||
PAS domain; This family includes the PAS-B domain of NCOA1 (Nuclear receptor coactivator 1), which binds to an LXXLL motif in the C-terminal region of STAT6 (Signal transducer and activator of transcription 6). The actual alignment was detected with superfamily member pfam14598: Pssm-ID: 464214 [Multi-domain] Cd Length: 110 Bit Score: 58.85 E-value: 1.76e-10
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PAS | smart00091 | PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising ... |
72-135 | 1.41e-06 | |||
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. : Pssm-ID: 214512 Cd Length: 67 Bit Score: 46.24 E-value: 1.41e-06
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Name | Accession | Description | Interval | E-value | |||
bHLH-PAS_NPAS4_PASD10 | cd19697 | basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in neuronal PAS domain-containing ... |
2-57 | 3.49e-33 | |||
basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in neuronal PAS domain-containing protein 4 (NPAS4) and similar proteins; NPAS4, also termed neuronal Per-Arnt-Sim homology (PAS) factor 4, or neuronal PAS4, or Class E basic helix-loop-helix protein 79 (bHLHe79), or HLH-PAS transcription factor NXF, or PAS domain-containing protein 10 (PASD10), is a bHLH-PAS neuronal activity-dependent transcription factor which heterodimerizes with ARNT2 to regulate genes involved in inhibitory synapse formation. Pssm-ID: 381540 Cd Length: 57 Bit Score: 121.64 E-value: 3.49e-33
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PAS_11 | pfam14598 | PAS domain; This family includes the PAS-B domain of NCOA1 (Nuclear receptor coactivator 1), ... |
217-319 | 1.76e-10 | |||
PAS domain; This family includes the PAS-B domain of NCOA1 (Nuclear receptor coactivator 1), which binds to an LXXLL motif in the C-terminal region of STAT6 (Signal transducer and activator of transcription 6). Pssm-ID: 464214 [Multi-domain] Cd Length: 110 Bit Score: 58.85 E-value: 1.76e-10
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PAS | cd00130 | PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising ... |
214-294 | 5.88e-07 | |||
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in signal transduction. Pssm-ID: 238075 [Multi-domain] Cd Length: 103 Bit Score: 48.40 E-value: 5.88e-07
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PAS | smart00091 | PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising ... |
72-135 | 1.41e-06 | |||
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. Pssm-ID: 214512 Cd Length: 67 Bit Score: 46.24 E-value: 1.41e-06
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PAS | cd00130 | PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising ... |
81-135 | 7.70e-05 | |||
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in signal transduction. Pssm-ID: 238075 [Multi-domain] Cd Length: 103 Bit Score: 42.62 E-value: 7.70e-05
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PAS | smart00091 | PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising ... |
220-271 | 7.85e-05 | |||
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. Pssm-ID: 214512 Cd Length: 67 Bit Score: 41.23 E-value: 7.85e-05
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PAS | COG2202 | PAS domain [Signal transduction mechanisms]; |
224-294 | 4.66e-04 | |||
PAS domain [Signal transduction mechanisms]; Pssm-ID: 441804 [Multi-domain] Cd Length: 258 Bit Score: 42.70 E-value: 4.66e-04
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Name | Accession | Description | Interval | E-value | |||
bHLH-PAS_NPAS4_PASD10 | cd19697 | basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in neuronal PAS domain-containing ... |
2-57 | 3.49e-33 | |||
basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in neuronal PAS domain-containing protein 4 (NPAS4) and similar proteins; NPAS4, also termed neuronal Per-Arnt-Sim homology (PAS) factor 4, or neuronal PAS4, or Class E basic helix-loop-helix protein 79 (bHLHe79), or HLH-PAS transcription factor NXF, or PAS domain-containing protein 10 (PASD10), is a bHLH-PAS neuronal activity-dependent transcription factor which heterodimerizes with ARNT2 to regulate genes involved in inhibitory synapse formation. Pssm-ID: 381540 Cd Length: 57 Bit Score: 121.64 E-value: 3.49e-33
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bHLH_PAS | cd11391 | basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain family; bHLH-PAS domain has been found ... |
2-56 | 1.28e-16 | |||
basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain family; bHLH-PAS domain has been found in a large group of bHLH transcription regulators that are involved in gene expression responding to environmental change and controlling aspects of neural development, including proteins from aryl hydrocarbon receptor nuclear translocator (ARNT) family, hypoxia-inducible factor (HIF) family, aryl hydrocarbon receptor (AhR) family, neuronal PAS domain-containing protein (NPAS) family, Circadian locomotor output cycles protein kaput (CLOCK)-like family, and single-minded (SIM) family. bHLH-PAS transcriptional regulatory factors have a bHLH DNA-binding domain followed by two PAS domains and a C-terminal activation or repression domain. bHLH-PAS family members can be divided into class I and class II based on their dimerization partner. bHLH-PAS class I factors include AhR, HIF and SIM. The best characterized bHLH-PAS Class II protein is the ubiquitous ARNT. Some members of bHLH-PAS family act as transcriptional coactivators (such as NCoA) that lack the ability to dimerize and bind DNA. Pssm-ID: 381397 [Multi-domain] Cd Length: 55 Bit Score: 74.15 E-value: 1.28e-16
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PAS_11 | pfam14598 | PAS domain; This family includes the PAS-B domain of NCOA1 (Nuclear receptor coactivator 1), ... |
217-319 | 1.76e-10 | |||
PAS domain; This family includes the PAS-B domain of NCOA1 (Nuclear receptor coactivator 1), which binds to an LXXLL motif in the C-terminal region of STAT6 (Signal transducer and activator of transcription 6). Pssm-ID: 464214 [Multi-domain] Cd Length: 110 Bit Score: 58.85 E-value: 1.76e-10
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PAS_3 | pfam08447 | PAS fold; The PAS fold corresponds to the structural domain that has previously been defined ... |
228-296 | 9.48e-10 | |||
PAS fold; The PAS fold corresponds to the structural domain that has previously been defined as PAS and PAC motifs. The PAS fold appears in archaea, eubacteria and eukarya. Pssm-ID: 430001 [Multi-domain] Cd Length: 89 Bit Score: 55.81 E-value: 9.48e-10
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PAS | cd00130 | PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising ... |
214-294 | 5.88e-07 | |||
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in signal transduction. Pssm-ID: 238075 [Multi-domain] Cd Length: 103 Bit Score: 48.40 E-value: 5.88e-07
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PAS | smart00091 | PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising ... |
72-135 | 1.41e-06 | |||
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. Pssm-ID: 214512 Cd Length: 67 Bit Score: 46.24 E-value: 1.41e-06
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PAS | cd00130 | PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising ... |
81-135 | 7.70e-05 | |||
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in signal transduction. Pssm-ID: 238075 [Multi-domain] Cd Length: 103 Bit Score: 42.62 E-value: 7.70e-05
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PAS | smart00091 | PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising ... |
220-271 | 7.85e-05 | |||
PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. Pssm-ID: 214512 Cd Length: 67 Bit Score: 41.23 E-value: 7.85e-05
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bHLH-PAS_AhR_like | cd19696 | basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in the aryl hydrocarbon receptor ... |
8-60 | 8.15e-05 | |||
basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in the aryl hydrocarbon receptor (AhR) family; The AhR family includes AhR, AhR repressor (AhRR) and Drosophila melanogaster protein spineless. AhR, also termed Ah receptor, or Dioxin receptor (DR), or Class E basic helix-loop-helix protein 76 (bHLHe76), is the only member of bHLH-PAS transcription regulators that bind and be activated by small chemical ligands. It is activated by Dioxin to control the expression of certain genes to influence biological processes such as apoptosis, proliferation, cell growth and differentiation. To form active DNA binding complexes AhR dimerizes with a bHLH-PAS factor ARNT (Aryl hydrocarbon Nuclear Receptor Translocator). AhRR, also termed Class E basic helix-loop-helix protein 77 (bHLHe77), is a member of bHLH-PAS transcription factors that acts as a negative regulator of AhR, playing key roles in development and environmental sensing. AhRR functions by competing with AhR for its partner ARNT. AhRR-ARNT complexes are transcriptionally inactive. Spineless is a bHLH-PAS transcription factor that plays an important role in fly morphogenesis. It is both necessary and sufficient for the formation of the ommatidial mosaic. Pssm-ID: 381539 Cd Length: 59 Bit Score: 41.12 E-value: 8.15e-05
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PAS | COG2202 | PAS domain [Signal transduction mechanisms]; |
224-294 | 4.66e-04 | |||
PAS domain [Signal transduction mechanisms]; Pssm-ID: 441804 [Multi-domain] Cd Length: 258 Bit Score: 42.70 E-value: 4.66e-04
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bHLH-PAS_AhR | cd11436 | basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in aryl hydrocarbon receptor (AhR) ... |
9-56 | 1.42e-03 | |||
basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in aryl hydrocarbon receptor (AhR) and similar proteins; AhR, also termed Ah receptor, or Dioxin receptor (DR), or Class E basic helix-loop-helix protein 76 (bHLHe76), is the only member of bHLH-PAS transcription regulators that bind and be activated by small chemical ligands. It is activated by Dioxin to control the expression of certain genes to influence biological processes such as apoptosis, proliferation, cell growth and differentiation. To form active DNA binding complexes AhR dimerize with a bHLH-PAS factor ARNT (Aryl hydrocarbon Nuclear Receptor Translocator). Pssm-ID: 381442 Cd Length: 61 Bit Score: 37.60 E-value: 1.42e-03
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MalT | COG2909 | ATP-, maltotriose- and DNA-dependent transcriptional regulator MalT [Transcription]; |
254-295 | 9.61e-03 | |||
ATP-, maltotriose- and DNA-dependent transcriptional regulator MalT [Transcription]; Pssm-ID: 442153 [Multi-domain] Cd Length: 184 Bit Score: 38.15 E-value: 9.61e-03
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