NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|30725847|ref|NP_850919|]
View 

receptor expression-enhancing protein 4 [Mus musculus]

Protein Classification

TB2_DP1_HVA22 and PRK11675 domain-containing protein( domain architecture ID 10504258)

TB2_DP1_HVA22 and PRK11675 domain-containing protein

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
TB2_DP1_HVA22 pfam03134
TB2/DP1, HVA22 family; This family includes members from a wide variety of eukaryotes. It ...
 19-94 4.39e-39

TB2/DP1, HVA22 family; This family includes members from a wide variety of eukaryotes. It includes the TB2/DP1 (deleted in polyposis) protein, which in humans is deleted in severe forms of familial adenomatous polyposis, an autosomal dominant oncological inherited disease. The family also includes the plant protein of known similarity to TB2/DP1, the HVA22 abscisic acid-induced protein, which is thought to be a regulatory protein.


:

Pssm-ID: 460820  Cd Length: 77  Bit Score: 130.70  E-value: 4.39e-39
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 30725847    19 PAYASYKAVKSKNIREYVRWMMYWIVFAIFMAAETFTDIFISWFPFYYEFKMAFVLWLLSPYTKGASLLYRKFVHP 94
Cdd:pfam03134   1 PAYASYKALESPDKDDDTQWLTYWVVFGFFTLVESFADFLLSWIPFYYEFKLLFLLWLVLPQTQGATYIYEKFLRP 76
PRK11675 super family cl08198
LexA regulated protein; Provisional
 211-243 9.40e-03

LexA regulated protein; Provisional


The actual alignment was detected with superfamily member PRK11675:

Pssm-ID: 183272  Cd Length: 90  Bit Score: 34.57  E-value: 9.40e-03
                         10        20        30
                 ....*....|....*....|....*....|...
gi 30725847  211 PVRPREKPLGRSQSLRVVKRKPLTREgTSRSLK 243
Cdd:PRK11675  20 PGRPKTNPLSRDEQLRINKRNQLKRD-KVRGLK 51
 
Name Accession Description Interval E-value
TB2_DP1_HVA22 pfam03134
TB2/DP1, HVA22 family; This family includes members from a wide variety of eukaryotes. It ...
 19-94 4.39e-39

TB2/DP1, HVA22 family; This family includes members from a wide variety of eukaryotes. It includes the TB2/DP1 (deleted in polyposis) protein, which in humans is deleted in severe forms of familial adenomatous polyposis, an autosomal dominant oncological inherited disease. The family also includes the plant protein of known similarity to TB2/DP1, the HVA22 abscisic acid-induced protein, which is thought to be a regulatory protein.


Pssm-ID: 460820  Cd Length: 77  Bit Score: 130.70  E-value: 4.39e-39
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 30725847    19 PAYASYKAVKSKNIREYVRWMMYWIVFAIFMAAETFTDIFISWFPFYYEFKMAFVLWLLSPYTKGASLLYRKFVHP 94
Cdd:pfam03134   1 PAYASYKALESPDKDDDTQWLTYWVVFGFFTLVESFADFLLSWIPFYYEFKLLFLLWLVLPQTQGATYIYEKFLRP 76
YOP1 COG5052
Protein involved in membrane traffic [Intracellular trafficking and secretion];
15-103 9.45e-16

Protein involved in membrane traffic [Intracellular trafficking and secretion];


Pssm-ID: 227385  Cd Length: 186  Bit Score: 72.91  E-value: 9.45e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30725847  15 GMLYPAYASYKAVKSKNIREYVRWMMYWIVFAIFMAAETFTDIFISWFPFYYEFKMAFVLWLLSPYTKGASLLYRKFVHP 94
Cdd:COG5052  67 GFSLPAQLSLVAFYTLNFMDDTQLLTYWMVFGFLSAIEKYSGAILSKVPFYWTLKNVFLLWLLLPRTEGARIIYDDIIAP 146


                ....*....
gi 30725847  95 SLSRHEKEI 103
Cdd:COG5052 147 DVSDHGFRT 155
PRK11675 PRK11675
LexA regulated protein; Provisional
 211-243 9.40e-03

LexA regulated protein; Provisional


Pssm-ID: 183272  Cd Length: 90  Bit Score: 34.57  E-value: 9.40e-03
                         10        20        30
                 ....*....|....*....|....*....|...
gi 30725847  211 PVRPREKPLGRSQSLRVVKRKPLTREgTSRSLK 243
Cdd:PRK11675  20 PGRPKTNPLSRDEQLRINKRNQLKRD-KVRGLK 51
 
Name Accession Description Interval E-value
TB2_DP1_HVA22 pfam03134
TB2/DP1, HVA22 family; This family includes members from a wide variety of eukaryotes. It ...
 19-94 4.39e-39

TB2/DP1, HVA22 family; This family includes members from a wide variety of eukaryotes. It includes the TB2/DP1 (deleted in polyposis) protein, which in humans is deleted in severe forms of familial adenomatous polyposis, an autosomal dominant oncological inherited disease. The family also includes the plant protein of known similarity to TB2/DP1, the HVA22 abscisic acid-induced protein, which is thought to be a regulatory protein.


Pssm-ID: 460820  Cd Length: 77  Bit Score: 130.70  E-value: 4.39e-39
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 30725847    19 PAYASYKAVKSKNIREYVRWMMYWIVFAIFMAAETFTDIFISWFPFYYEFKMAFVLWLLSPYTKGASLLYRKFVHP 94
Cdd:pfam03134   1 PAYASYKALESPDKDDDTQWLTYWVVFGFFTLVESFADFLLSWIPFYYEFKLLFLLWLVLPQTQGATYIYEKFLRP 76
YOP1 COG5052
Protein involved in membrane traffic [Intracellular trafficking and secretion];
15-103 9.45e-16

Protein involved in membrane traffic [Intracellular trafficking and secretion];


Pssm-ID: 227385  Cd Length: 186  Bit Score: 72.91  E-value: 9.45e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30725847  15 GMLYPAYASYKAVKSKNIREYVRWMMYWIVFAIFMAAETFTDIFISWFPFYYEFKMAFVLWLLSPYTKGASLLYRKFVHP 94
Cdd:COG5052  67 GFSLPAQLSLVAFYTLNFMDDTQLLTYWMVFGFLSAIEKYSGAILSKVPFYWTLKNVFLLWLLLPRTEGARIIYDDIIAP 146


                ....*....
gi 30725847  95 SLSRHEKEI 103
Cdd:COG5052 147 DVSDHGFRT 155
PRK11675 PRK11675
LexA regulated protein; Provisional
 211-243 9.40e-03

LexA regulated protein; Provisional


Pssm-ID: 183272  Cd Length: 90  Bit Score: 34.57  E-value: 9.40e-03
                         10        20        30
                 ....*....|....*....|....*....|...
gi 30725847  211 PVRPREKPLGRSQSLRVVKRKPLTREgTSRSLK 243
Cdd:PRK11675  20 PGRPKTNPLSRDEQLRINKRNQLKRD-KVRGLK 51
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH