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Conserved domains on  [gi|114158654|ref|NP_898954|]
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fertilization-influencing membrane protein precursor [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
FIMP super family cl39210
fertilization-influencing membrane protein; In mice, 4930451I11Rik encodes two isoforms: a ...
 24-111 2.48e-26

fertilization-influencing membrane protein; In mice, 4930451I11Rik encodes two isoforms: a transmembrane (TM) form and a secreted form. FIMP is the TM form. It is a sperm-specific transmembrane protein that is essential for the sperm-oocyte fusion process.


The actual alignment was detected with superfamily member pfam17672:

Pssm-ID: 465449  Cd Length: 89  Bit Score: 93.37  E-value: 2.48e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114158654   24 APRRDGTRPSVSGARPQQVVNRL-FFDYPDSDRASLLAVARFIGEKPITFVKTDSSPGLFQNILVGTLVVAFFFLLFQFC 102
Cdd:pfam17672   1 APRPKSANALARGAESPRFIDRPdFFDYPDSDQARLLAVAQFIGEKPVIFVNSGSSSGLFHHILVGALVVAFFFLLFQFC 80


                  ....*....
gi 114158654  103 LHVNFQKGA 111
Cdd:pfam17672  81 THMSFQKGA 89
 
Name Accession Description Interval E-value
FIMP pfam17672
fertilization-influencing membrane protein; In mice, 4930451I11Rik encodes two isoforms: a ...
 24-111 2.48e-26

fertilization-influencing membrane protein; In mice, 4930451I11Rik encodes two isoforms: a transmembrane (TM) form and a secreted form. FIMP is the TM form. It is a sperm-specific transmembrane protein that is essential for the sperm-oocyte fusion process.


Pssm-ID: 465449  Cd Length: 89  Bit Score: 93.37  E-value: 2.48e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114158654   24 APRRDGTRPSVSGARPQQVVNRL-FFDYPDSDRASLLAVARFIGEKPITFVKTDSSPGLFQNILVGTLVVAFFFLLFQFC 102
Cdd:pfam17672   1 APRPKSANALARGAESPRFIDRPdFFDYPDSDQARLLAVAQFIGEKPVIFVNSGSSSGLFHHILVGALVVAFFFLLFQFC 80


                  ....*....
gi 114158654  103 LHVNFQKGA 111
Cdd:pfam17672  81 THMSFQKGA 89
 
Name Accession Description Interval E-value
FIMP pfam17672
fertilization-influencing membrane protein; In mice, 4930451I11Rik encodes two isoforms: a ...
 24-111 2.48e-26

fertilization-influencing membrane protein; In mice, 4930451I11Rik encodes two isoforms: a transmembrane (TM) form and a secreted form. FIMP is the TM form. It is a sperm-specific transmembrane protein that is essential for the sperm-oocyte fusion process.


Pssm-ID: 465449  Cd Length: 89  Bit Score: 93.37  E-value: 2.48e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 114158654   24 APRRDGTRPSVSGARPQQVVNRL-FFDYPDSDRASLLAVARFIGEKPITFVKTDSSPGLFQNILVGTLVVAFFFLLFQFC 102
Cdd:pfam17672   1 APRPKSANALARGAESPRFIDRPdFFDYPDSDQARLLAVAQFIGEKPVIFVNSGSSSGLFHHILVGALVVAFFFLLFQFC 80


                  ....*....
gi 114158654  103 LHVNFQKGA 111
Cdd:pfam17672  81 THMSFQKGA 89
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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