|
Name |
Accession |
Description |
Interval |
E-value |
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
66-197 |
1.70e-17 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 85.76 E-value: 1.70e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238637334 66 QLFLNGNLLTRLyPNEFVNYSNAVTLHLGNNGLQEIrPGAFSGLKTLKRLHLNNNKLEVLREDtFLGLESLEYLQADYNY 145
Cdd:COG4886 117 SLDLSGNQLTDL-PEELANLTNLKELDLSNNQLTDL-PEPLGNLTNLKSLDLSNNQLTDLPEE-LGNLTNLKELDLSNNQ 193
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 238637334 146 ISTIEAgAFSKLNKLKVLILNDNLLLSLPSNVFRFVLLTHLDLRGNRLKVMP 197
Cdd:COG4886 194 ITDLPE-PLGNLTNLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQLTDLP 244
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
400-460 |
5.29e-14 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 67.16 E-value: 5.29e-14
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 238637334 400 SSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVI 460
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
86-146 |
8.87e-14 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 66.39 E-value: 8.87e-14
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 238637334 86 SNAVTLHLGNNGLQEIRPGAFSGLKTLKRLHLNNNKLEVLREDTFLGLESLEYLQADYNYI 146
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
379-530 |
6.85e-12 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 68.42 E-value: 6.85e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238637334 379 KKLYLTGNYLQTVYKnDLLEYSSLDLLHLGNNRIAVIQEgAFTNLTSLRRLYLNGNYLEVLyPSMFDGLQSLQYLYLEYN 458
Cdd:COG4886 139 KELDLSNNQLTDLPE-PLGNLTNLKSLDLSNNQLTDLPE-ELGNLTNLKELDLSNNQITDL-PEPLGNLTNLEELDLSGN 215
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 238637334 459 VIKEIkpltfdalinlqllflnnnllrslPDNIFGGTALTRLNLRNNHFSHLPvkgVLDQLPAFIQIDLQEN 530
Cdd:COG4886 216 QLTDL------------------------PEPLANLTNLETLDLSNNQLTDLP---ELGNLTNLEELDLSNN 260
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
358-531 |
2.00e-09 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 58.64 E-value: 2.00e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238637334 358 VNCQERKFTNISDLQPkPTSPKKLYLTGNYLQTVykNDLLEYSSLDLLHLGNNRIAVIqEGaFTNLTSLRRLYLNGNYLE 437
Cdd:cd21340 7 LYLNDKNITKIDNLSL-CKNLKVLYLYDNKITKI--ENLEFLTNLTHLYLQNNQIEKI-EN-LENLVNLKKLYLGGNRIS 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238637334 438 VLypSMFDGLQSLQYLYLEYNVIKEIKPLTFDalinlqllflnnnllrslPDNIFG-----------G------------ 494
Cdd:cd21340 82 VV--EGLENLTNLEELHIENQRLPPGEKLTFD------------------PRSLAAlsnslrvlnisGnnidsleplapl 141
|
170 180 190
....*....|....*....|....*....|....*...
gi 238637334 495 TALTRLNLRNNHFSHL-PVKGVLDQLPAFIQIDLQENP 531
Cdd:cd21340 142 RNLEQLDASNNQISDLeELLDLLSSWPSLRELDLTGNP 179
|
|
| LRRCT |
smart00082 |
Leucine rich repeat C-terminal domain; |
530-580 |
1.24e-07 |
|
Leucine rich repeat C-terminal domain;
Pssm-ID: 214507 [Multi-domain] Cd Length: 51 Bit Score: 48.97 E-value: 1.24e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 238637334 530 NPWDCTCDIMGLKDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICP 580
Cdd:smart00082 1 NPFICDCELRWLLRWLQANEHLQDPVDLRCASPSSLRGPLLELLHSEFKCP 51
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
67-191 |
3.54e-06 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 49.01 E-value: 3.54e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238637334 67 LFLNGNLLTRLyPNeFVNYSNAVTLHLGNNGLQEIRPgaFSGLKTLKRLHLNNNKLEV---------LRE---------- 127
Cdd:cd21340 29 LYLYDNKITKI-EN-LEFLTNLTHLYLQNNQIEKIEN--LENLVNLKKLYLGGNRISVveglenltnLEElhienqrlpp 104
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 238637334 128 --------DTFLGL-ESLEYLQADYNYISTIEagAFSKLNKLKVLILNDNLLLSLP--SNVFR-FVLLTHLDLRGN 191
Cdd:cd21340 105 gekltfdpRSLAALsNSLRVLNISGNNIDSLE--PLAPLRNLEQLDASNNQISDLEelLDLLSsWPSLRELDLTGN 178
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
64-193 |
1.62e-04 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 45.61 E-value: 1.62e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238637334 64 IYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRPGAFSGLKTLKRLHLNNNKL--EVLREdtfLG-LESLEYLQ 140
Cdd:PLN00113 142 LETLDLSNNMLSGEIPNDIGSFSSLKVLDLGGNVLVGKIPNSLTNLTSLEFLTLASNQLvgQIPRE---LGqMKSLKWIY 218
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 238637334 141 ADYNYIS---TIEAGAFSKLNKLKvLILNdNLLLSLPSNVFRFVLLTHLDLRGNRL 193
Cdd:PLN00113 219 LGYNNLSgeiPYEIGGLTSLNHLD-LVYN-NLTGPIPSSLGNLKNLQYLFLYQNKL 272
|
|
| LRRCT |
smart00082 |
Leucine rich repeat C-terminal domain; |
216-252 |
1.92e-04 |
|
Leucine rich repeat C-terminal domain;
Pssm-ID: 214507 [Multi-domain] Cd Length: 51 Bit Score: 39.72 E-value: 1.92e-04
10 20 30
....*....|....*....|....*....|....*....
gi 238637334 216 NPWNCTCDLLPLKAWLDTITVFVG--EIVCETPFRLHGK 252
Cdd:smart00082 1 NPFICDCELRWLLRWLQANEHLQDpvDLRCASPSSLRGP 39
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
381-458 |
2.34e-03 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 41.76 E-value: 2.34e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 238637334 381 LYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYN 458
Cdd:PLN00113 145 LDLSNNMLSGEIPNDIGSFSSLKVLDLGGNVLVGKIPNSLTNLTSLEFLTLASNQLVGQIPRELGQMKSLKWIYLGYN 222
|
|
|
|
Name |
Accession |
Description |
Interval |
E-value |
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
66-197 |
1.70e-17 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 85.76 E-value: 1.70e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238637334 66 QLFLNGNLLTRLyPNEFVNYSNAVTLHLGNNGLQEIrPGAFSGLKTLKRLHLNNNKLEVLREDtFLGLESLEYLQADYNY 145
Cdd:COG4886 117 SLDLSGNQLTDL-PEELANLTNLKELDLSNNQLTDL-PEPLGNLTNLKSLDLSNNQLTDLPEE-LGNLTNLKELDLSNNQ 193
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 238637334 146 ISTIEAgAFSKLNKLKVLILNDNLLLSLPSNVFRFVLLTHLDLRGNRLKVMP 197
Cdd:COG4886 194 ITDLPE-PLGNLTNLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQLTDLP 244
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
66-217 |
3.34e-17 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 84.99 E-value: 3.34e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238637334 66 QLFLNGNLLTRLyPNEFVNYSNAVTLHLGNNGLQEIrPGAFSGLKTLKRLHLNNNKLEVLrEDTFLGLESLEYLQADYNY 145
Cdd:COG4886 140 ELDLSNNQLTDL-PEPLGNLTNLKSLDLSNNQLTDL-PEELGNLTNLKELDLSNNQITDL-PEPLGNLTNLEELDLSGNQ 216
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 238637334 146 ISTIEAgAFSKLNKLKVLILNDNLLLSLPSnVFRFVLLTHLDLRGNRLKVMPFAGVLEHIGgimEIQLEENP 217
Cdd:COG4886 217 LTDLPE-PLANLTNLETLDLSNNQLTDLPE-LGNLTNLEELDLSNNQLTDLPPLANLTNLK---TLDLSNNQ 283
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
400-460 |
5.29e-14 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 67.16 E-value: 5.29e-14
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 238637334 400 SSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVI 460
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
86-146 |
8.87e-14 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 66.39 E-value: 8.87e-14
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 238637334 86 SNAVTLHLGNNGLQEIRPGAFSGLKTLKRLHLNNNKLEVLREDTFLGLESLEYLQADYNYI 146
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
111-170 |
2.62e-13 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 65.24 E-value: 2.62e-13
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 238637334 111 TLKRLHLNNNKLEVLREDTFLGLESLEYLQADYNYISTIEAGAFSKLNKLKVLILNDNLL 170
Cdd:pfam13855 2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
379-530 |
6.85e-12 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 68.42 E-value: 6.85e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238637334 379 KKLYLTGNYLQTVYKnDLLEYSSLDLLHLGNNRIAVIQEgAFTNLTSLRRLYLNGNYLEVLyPSMFDGLQSLQYLYLEYN 458
Cdd:COG4886 139 KELDLSNNQLTDLPE-PLGNLTNLKSLDLSNNQLTDLPE-ELGNLTNLKELDLSNNQITDL-PEPLGNLTNLEELDLSGN 215
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 238637334 459 VIKEIkpltfdalinlqllflnnnllrslPDNIFGGTALTRLNLRNNHFSHLPvkgVLDQLPAFIQIDLQEN 530
Cdd:COG4886 216 QLTDL------------------------PEPLANLTNLETLDLSNNQLTDLP---ELGNLTNLEELDLSNN 260
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
359-531 |
1.38e-10 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 64.18 E-value: 1.38e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238637334 359 NCQERKFTNISDLQPKPTSPKKLYLTGNYLQTVyKNDLLEYSSLDLLHLGNNRIAVIQEgAFTNLTSLRRLYLNGNYLEV 438
Cdd:COG4886 142 DLSNNQLTDLPEPLGNLTNLKSLDLSNNQLTDL-PEELGNLTNLKELDLSNNQITDLPE-PLGNLTNLEELDLSGNQLTD 219
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238637334 439 LyPSMFDGLQSLQYLYLEYNVIKEIkpltfdalinlqllflnnnllrslpDNIFGGTALTRLNLRNNHFSHLPvkgVLDQ 518
Cdd:COG4886 220 L-PEPLANLTNLETLDLSNNQLTDL-------------------------PELGNLTNLEELDLSNNQLTDLP---PLAN 270
|
170
....*....|...
gi 238637334 519 LPAFIQIDLQENP 531
Cdd:COG4886 271 LTNLKTLDLSNNQ 283
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
358-531 |
2.00e-09 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 58.64 E-value: 2.00e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238637334 358 VNCQERKFTNISDLQPkPTSPKKLYLTGNYLQTVykNDLLEYSSLDLLHLGNNRIAVIqEGaFTNLTSLRRLYLNGNYLE 437
Cdd:cd21340 7 LYLNDKNITKIDNLSL-CKNLKVLYLYDNKITKI--ENLEFLTNLTHLYLQNNQIEKI-EN-LENLVNLKKLYLGGNRIS 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238637334 438 VLypSMFDGLQSLQYLYLEYNVIKEIKPLTFDalinlqllflnnnllrslPDNIFG-----------G------------ 494
Cdd:cd21340 82 VV--EGLENLTNLEELHIENQRLPPGEKLTFD------------------PRSLAAlsnslrvlnisGnnidsleplapl 141
|
170 180 190
....*....|....*....|....*....|....*...
gi 238637334 495 TALTRLNLRNNHFSHL-PVKGVLDQLPAFIQIDLQENP 531
Cdd:cd21340 142 RNLEQLDASNNQISDLeELLDLLSSWPSLRELDLTGNP 179
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
135-193 |
3.08e-09 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 53.68 E-value: 3.08e-09
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 238637334 135 SLEYLQADYNYISTIEAGAFSKLNKLKVLILNDNLLLSLPSNVFR-FVLLTHLDLRGNRL 193
Cdd:pfam13855 2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSgLPSLRYLDLSGNRL 61
|
|
| LRRCT |
smart00082 |
Leucine rich repeat C-terminal domain; |
530-580 |
1.24e-07 |
|
Leucine rich repeat C-terminal domain;
Pssm-ID: 214507 [Multi-domain] Cd Length: 51 Bit Score: 48.97 E-value: 1.24e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 238637334 530 NPWDCTCDIMGLKDWTEHANSPVIINEVTCESPAKHAGEILKFLGREAICP 580
Cdd:smart00082 1 NPFICDCELRWLLRWLQANEHLQDPVDLRCASPSSLRGPLLELLHSEFKCP 51
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
366-528 |
1.68e-07 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 54.55 E-value: 1.68e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238637334 366 TNISDLqPKPTSP----KKLYLTGNYLQTVyKNDLLEYSSLDLLHLGNNRIAVIqEGAFTNLTSLRRLYLNGNYLEVLyP 441
Cdd:COG4886 169 NQLTDL-PEELGNltnlKELDLSNNQITDL-PEPLGNLTNLEELDLSGNQLTDL-PEPLANLTNLETLDLSNNQLTDL-P 244
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238637334 442 SMFdGLQSLQYLYLEYNVIKEIKPLtfdalinlqllflnnnllrslpdniFGGTALTRLNLRNNHFSHLPVKGVLDQLPA 521
Cdd:COG4886 245 ELG-NLTNLEELDLSNNQLTDLPPL-------------------------ANLTNLKTLDLSNNQLTDLKLKELELLLGL 298
|
....*..
gi 238637334 522 FIQIDLQ 528
Cdd:COG4886 299 NSLLLLL 305
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
424-507 |
4.51e-07 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 47.52 E-value: 4.51e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238637334 424 TSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYNVIKEIKPLTFDalinlqllflnnnllrslpdnifGGTALTRLNLR 503
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFS-----------------------GLPSLRYLDLS 57
|
....
gi 238637334 504 NNHF 507
Cdd:pfam13855 58 GNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
67-122 |
6.95e-07 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 47.13 E-value: 6.95e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 238637334 67 LFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRPGAFSGLKTLKRLHLNNNKL 122
Cdd:pfam13855 6 LDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
366-505 |
1.29e-06 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 51.86 E-value: 1.29e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238637334 366 TNISDLQP---KPTSPKKLYLTGNYLQTVyKNDLLEYSSLDLLHLGNNRIAVIQEgaFTNLTSLRRLYLNGNYLEVLYPS 442
Cdd:COG4886 192 NQITDLPEplgNLTNLEELDLSGNQLTDL-PEPLANLTNLETLDLSNNQLTDLPE--LGNLTNLEELDLSNNQLTDLPPL 268
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 238637334 443 MfdGLQSLQYLYLEYNVIKEIKPLTFDALINLQLLFLNNNLLRSLPDNIFGGTALTRLNLRNN 505
Cdd:COG4886 269 A--NLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLL 329
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
67-191 |
3.54e-06 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 49.01 E-value: 3.54e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238637334 67 LFLNGNLLTRLyPNeFVNYSNAVTLHLGNNGLQEIRPgaFSGLKTLKRLHLNNNKLEV---------LRE---------- 127
Cdd:cd21340 29 LYLYDNKITKI-EN-LEFLTNLTHLYLQNNQIEKIEN--LENLVNLKKLYLGGNRISVveglenltnLEElhienqrlpp 104
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 238637334 128 --------DTFLGL-ESLEYLQADYNYISTIEagAFSKLNKLKVLILNDNLLLSLP--SNVFR-FVLLTHLDLRGN 191
Cdd:cd21340 105 gekltfdpRSLAALsNSLRVLNISGNNIDSLE--PLAPLRNLEQLDASNNQISDLEelLDLLSsWPSLRELDLTGN 178
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
63-260 |
1.64e-05 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 46.70 E-value: 1.64e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238637334 63 RIYQLFLNGNLLTRLypNEFVNYSNAVTLHLGNNGLQEIRpgAFSGLKTLKRLHLNNNKLEVLRedtflGLESLEYLQ-- 140
Cdd:cd21340 3 RITHLYLNDKNITKI--DNLSLCKNLKVLYLYDNKITKIE--NLEFLTNLTHLYLQNNQIEKIE-----NLENLVNLKkl 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238637334 141 -ADYNYISTIE----------------------------AGAFSKLNKLKVLILNDNLLLSLpSNVFRFVLLTHLDLRGN 191
Cdd:cd21340 74 yLGGNRISVVEglenltnleelhienqrlppgekltfdpRSLAALSNSLRVLNISGNNIDSL-EPLAPLRNLEQLDASNN 152
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238637334 192 RLKVM-PFAGVLEHIGGIMEIQLEENPwnctcdLLPLKAWLDTITVFVGEIVCetpfrLHGKDVTQLTRQ 260
Cdd:cd21340 153 QISDLeELLDLLSSWPSLRELDLTGNP------VCKKPKYRDKIILASKSLEV-----LDGKEITDTERQ 211
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
64-193 |
1.62e-04 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 45.61 E-value: 1.62e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238637334 64 IYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRPGAFSGLKTLKRLHLNNNKL--EVLREdtfLG-LESLEYLQ 140
Cdd:PLN00113 142 LETLDLSNNMLSGEIPNDIGSFSSLKVLDLGGNVLVGKIPNSLTNLTSLEFLTLASNQLvgQIPRE---LGqMKSLKWIY 218
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 238637334 141 ADYNYIS---TIEAGAFSKLNKLKvLILNdNLLLSLPSNVFRFVLLTHLDLRGNRL 193
Cdd:PLN00113 219 LGYNNLSgeiPYEIGGLTSLNHLD-LVYN-NLTGPIPSSLGNLKNLQYLFLYQNKL 272
|
|
| LRRCT |
smart00082 |
Leucine rich repeat C-terminal domain; |
216-252 |
1.92e-04 |
|
Leucine rich repeat C-terminal domain;
Pssm-ID: 214507 [Multi-domain] Cd Length: 51 Bit Score: 39.72 E-value: 1.92e-04
10 20 30
....*....|....*....|....*....|....*....
gi 238637334 216 NPWNCTCDLLPLKAWLDTITVFVG--EIVCETPFRLHGK 252
Cdd:smart00082 1 NPFICDCELRWLLRWLQANEHLQDpvDLRCASPSSLRGP 39
|
|
| PLN03150 |
PLN03150 |
hypothetical protein; Provisional |
91-170 |
5.14e-04 |
|
hypothetical protein; Provisional
Pssm-ID: 178695 [Multi-domain] Cd Length: 623 Bit Score: 43.65 E-value: 5.14e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238637334 91 LHLGNNGLQEIRPGAFSGLKTLKRLHLNNNKLEVLREDTFLGLESLEYLQADYNYISTIEAGAFSKLNKLKVLILNDNLL 170
Cdd:PLN03150 423 LGLDNQGLRGFIPNDISKLRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNSL 502
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
40-197 |
1.23e-03 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 42.23 E-value: 1.23e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238637334 40 NVLNINCENKGFTTVSLLQPPQYRIYQLFLNGNLLTRLYPNEFVNYSNAVTL-HLGNNGLQEIRPGAFSGLKTLKRLHLN 118
Cdd:COG4886 1 LLLLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLlSLLLRDLLLSSLLLLLSLLLLLLLSLL 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 238637334 119 NNKLEVLREDTFLGLESLEYLQADYNyistieaGAFSKLNKLKVLILNDNLLLSLPSNVFRFVLLTHLDLRGNRLKVMP 197
Cdd:COG4886 81 LLSLLLLGLTDLGDLTNLTELDLSGN-------EELSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLP 152
|
|
| LRR_5 |
pfam13306 |
BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich ... |
96-191 |
1.53e-03 |
|
BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich repeats. This family contains a large number of BSPA-like surface antigens from Trichomonas vaginalis.
Pssm-ID: 463839 [Multi-domain] Cd Length: 127 Bit Score: 39.45 E-value: 1.53e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238637334 96 NGLQEIRPGAFSGLKTLKRLHLNNNkLEVLREDTFLG--LESLEYLqadyNYISTIEAGAFSKLNKLKVLILNDNlLLSL 173
Cdd:pfam13306 20 SSLTSIGEYAFSNCTSLKSITLPSS-LTSIGSYAFYNcsLTSITIP----SSLTSIGEYAFSNCSNLKSITLPSN-LTSI 93
|
90
....*....|....*...
gi 238637334 174 PSNVFRFVLLTHLDLRGN 191
Cdd:pfam13306 94 GSYAFSNCSLKSITIPSS 111
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
381-458 |
2.34e-03 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 41.76 E-value: 2.34e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 238637334 381 LYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQEGAFTNLTSLRRLYLNGNYLEVLYPSMFDGLQSLQYLYLEYN 458
Cdd:PLN00113 145 LDLSNNMLSGEIPNDIGSFSSLKVLDLGGNVLVGKIPNSLTNLTSLEFLTLASNQLVGQIPRELGQMKSLKWIYLGYN 222
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
338-530 |
4.53e-03 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 40.30 E-value: 4.53e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238637334 338 ALTCPSSCVCTSQSSDNGLNVNCQERKFTNISDLQPKPTSPKKLYLTGNYLQTVYKNDLLEYSSLDLLHLGNNRIAVIQE 417
Cdd:COG4886 12 LLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTD 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238637334 418 gaFTNLTSLRRLYLNGNylevlypSMFDGLQSLQYLYLEYNVIKEIkpltfdalinlqllflnnnllrslPDNIFGGTAL 497
Cdd:COG4886 92 --LGDLTNLTELDLSGN-------EELSNLTNLESLDLSGNQLTDL------------------------PEELANLTNL 138
|
170 180 190
....*....|....*....|....*....|...
gi 238637334 498 TRLNLRNNHFSHLPVkgVLDQLPAFIQIDLQEN 530
Cdd:COG4886 139 KELDLSNNQLTDLPE--PLGNLTNLKSLDLSNN 169
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
82-217 |
8.21e-03 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 39.26 E-value: 8.21e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238637334 82 FVNYSNAVTLHLGNNGLQEIRPGAFSGL---KTLKRLHLNNNKLEVLREDTFL-GL----ESLEYLQADYNYI---STIE 150
Cdd:cd00116 77 LTKGCGLQELDLSDNALGPDGCGVLESLlrsSSLQELKLNNNGLGDRGLRLLAkGLkdlpPALEKLVLGRNRLegaSCEA 156
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 238637334 151 -AGAFSKLNKLKVLILNDN---------LLLSLPSNvfrfVLLTHLDLRGNRLK---VMPFAGVLEHIGGIMEIQLEENP 217
Cdd:cd00116 157 lAKALRANRDLKELNLANNgigdagiraLAEGLKAN----CNLEVLDLNNNGLTdegASALAETLASLKSLEVLNLGDNN 232
|
|
|