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Conserved domains on  [gi|45554773|ref|NP_996402|]
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discs large 1, isoform J [Drosophila melanogaster]

Protein Classification

L27_1 domain-containing protein( domain architecture ID 10557261)

L27_1 domain-containing protein

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
L27_1 pfam09058
L27_1; The L27 domain is a protein interaction module that exists in a large family of ...
6-64 3.80e-25

L27_1; The L27 domain is a protein interaction module that exists in a large family of scaffold proteins, functioning as an organization centre of large protein assemblies required for the establishment and maintenance of cell polarity. L27 domains form specific heterotetrameric complexes, in which each domain contains three alpha-helices.


:

Pssm-ID: 462665  Cd Length: 59  Bit Score: 92.74  E-value: 3.80e-25
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 45554773     6 QEAHRALELLEDYHARLSEPQDRALRIAIERVIRIFKSRLFQALLDIQEFYELTLLDDS 64
Cdd:pfam09058   1 SDEERALELLEEYHATLSRPDDEELRRAIERLINIFKSNLFQALLDIQEFYEVTLLSNR 59
 
Name Accession Description Interval E-value
L27_1 pfam09058
L27_1; The L27 domain is a protein interaction module that exists in a large family of ...
6-64 3.80e-25

L27_1; The L27 domain is a protein interaction module that exists in a large family of scaffold proteins, functioning as an organization centre of large protein assemblies required for the establishment and maintenance of cell polarity. L27 domains form specific heterotetrameric complexes, in which each domain contains three alpha-helices.


Pssm-ID: 462665  Cd Length: 59  Bit Score: 92.74  E-value: 3.80e-25
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 45554773     6 QEAHRALELLEDYHARLSEPQDRALRIAIERVIRIFKSRLFQALLDIQEFYELTLLDDS 64
Cdd:pfam09058   1 SDEERALELLEEYHATLSRPDDEELRRAIERLINIFKSNLFQALLDIQEFYEVTLLSNR 59
L27 smart00569
domain in receptor targeting proteins Lin-2 and Lin-7;
9-67 1.91e-07

domain in receptor targeting proteins Lin-2 and Lin-7;


Pssm-ID: 197794  Cd Length: 53  Bit Score: 46.35  E-value: 1.91e-07
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 45554773      9 HRALELLEDYHARLSEPQDRA-LRiaierviRIFKSRLFQALLDIQEFYELTLLDDSKSI 67
Cdd:smart00569   1 QRLLELLEELQSLLSPSEDLQeLR-------RLLQSPHLQALLKIHDKVAETELDPPLPE 53
 
Name Accession Description Interval E-value
L27_1 pfam09058
L27_1; The L27 domain is a protein interaction module that exists in a large family of ...
6-64 3.80e-25

L27_1; The L27 domain is a protein interaction module that exists in a large family of scaffold proteins, functioning as an organization centre of large protein assemblies required for the establishment and maintenance of cell polarity. L27 domains form specific heterotetrameric complexes, in which each domain contains three alpha-helices.


Pssm-ID: 462665  Cd Length: 59  Bit Score: 92.74  E-value: 3.80e-25
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 45554773     6 QEAHRALELLEDYHARLSEPQDRALRIAIERVIRIFKSRLFQALLDIQEFYELTLLDDS 64
Cdd:pfam09058   1 SDEERALELLEEYHATLSRPDDEELRRAIERLINIFKSNLFQALLDIQEFYEVTLLSNR 59
L27 smart00569
domain in receptor targeting proteins Lin-2 and Lin-7;
9-67 1.91e-07

domain in receptor targeting proteins Lin-2 and Lin-7;


Pssm-ID: 197794  Cd Length: 53  Bit Score: 46.35  E-value: 1.91e-07
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 45554773      9 HRALELLEDYHARLSEPQDRA-LRiaierviRIFKSRLFQALLDIQEFYELTLLDDSKSI 67
Cdd:smart00569   1 QRLLELLEELQSLLSPSEDLQeLR-------RLLQSPHLQALLKIHDKVAETELDPPLPE 53
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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