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Conserved domains on  [gi|46877066|ref|NP_997182|]
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phospholipid phosphatase-related protein type 1 [Homo sapiens]

Protein Classification

PAP2 phosphatase family protein( domain architecture ID 10130187)

type 2 phosphatidic acid phosphatase (PAP2) family protein similar to phospholipid phosphatase that catalyzes the conversion of phosphatidic acid to diacylglycerol

CATH:  1.20.144.10
EC:  3.1.3.-
Gene Ontology:  GO:0042577|GO:0046839|GO:0008610
PubMed:  9122162|12447906|9260289
SCOP:  3001110|4001226

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
PAP2_wunen cd03384
PAP2, wunen subfamily. Most likely a family of membrane associated phosphatidic acid ...
 123-272 6.91e-71

PAP2, wunen subfamily. Most likely a family of membrane associated phosphatidic acid phosphatases. Wunen is a drosophila protein expressed in the central nervous system, which provides repellent activity towards primordial germ cells (PGCs), controls the survival of PGCs and is essential in the migration process of these cells towards the somatic gonadal precursors.


:

Pssm-ID: 239479  Cd Length: 150  Bit Score: 216.73  E-value: 6.91e-71
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46877066 123 RIIRFTGVFAFGLFATDIFVNAGQVVTGHLTPYFLTVCKPNYTSADCQAHHQFINNGNICTGDLEVIEKARRSFPSKHAA 202
Cdd:cd03384   1 RLYRFVGVFLFGLFATQLLTDLGKYVTGRLRPHFLDVCKPNYTDLTCSLDHQYIADCTCCTGDPDLIREARLSFPSGHAS 80

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46877066 203 LSIYSALYATMYITSTIKTKSSRLAKPVLCLGTLCTAFLTGLNRVSEYRNHCSDVIAGFILGTAVALFLG 272
Cdd:cd03384  81 LSMYAAVFLALYLQARLKLRGSRLLRPLLQFLLLALALYVGLSRISDYKHHWSDVLAGALLGSVIALFLV 150
 
Name Accession Description Interval E-value
PAP2_wunen cd03384
PAP2, wunen subfamily. Most likely a family of membrane associated phosphatidic acid ...
 123-272 6.91e-71

PAP2, wunen subfamily. Most likely a family of membrane associated phosphatidic acid phosphatases. Wunen is a drosophila protein expressed in the central nervous system, which provides repellent activity towards primordial germ cells (PGCs), controls the survival of PGCs and is essential in the migration process of these cells towards the somatic gonadal precursors.


Pssm-ID: 239479  Cd Length: 150  Bit Score: 216.73  E-value: 6.91e-71
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46877066 123 RIIRFTGVFAFGLFATDIFVNAGQVVTGHLTPYFLTVCKPNYTSADCQAHHQFINNGNICTGDLEVIEKARRSFPSKHAA 202
Cdd:cd03384   1 RLYRFVGVFLFGLFATQLLTDLGKYVTGRLRPHFLDVCKPNYTDLTCSLDHQYIADCTCCTGDPDLIREARLSFPSGHAS 80

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46877066 203 LSIYSALYATMYITSTIKTKSSRLAKPVLCLGTLCTAFLTGLNRVSEYRNHCSDVIAGFILGTAVALFLG 272
Cdd:cd03384  81 LSMYAAVFLALYLQARLKLRGSRLLRPLLQFLLLALALYVGLSRISDYKHHWSDVLAGALLGSVIALFLV 150
PAP2 pfam01569
PAP2 superfamily; This family includes the enzyme type 2 phosphatidic acid phosphatase (PAP2), ...
 131-271 8.84e-13

PAP2 superfamily; This family includes the enzyme type 2 phosphatidic acid phosphatase (PAP2), Glucose-6-phosphatase EC:3.1.3.9, Phosphatidylglycerophosphatase B EC:3.1.3.27 and bacterial acid phosphatase EC:3.1.3.2. The family also includes a variety of haloperoxidases that function by oxidising halides in the presence of hydrogen peroxide to form the corresponding hypohalous acids.


Pssm-ID: 426329 [Multi-domain]  Cd Length: 124  Bit Score: 64.36  E-value: 8.84e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46877066   131 FAFGLFATDIFVNAGQVVTGHLTPYFLTVCKPNYTSADCQahhqfinngnictgdleviEKARRSFPSKHAALSIYSALY 210
Cdd:pfam01569   2 LLLALALAGLLSSVLKDYFGRPRPFFLLLEGGLVPAPSTL-------------------PGLGYSFPSGHSATAFALALL 62

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 46877066   211 ATMYITSTIKTKssrlaKPVLCLGTLCTAFLTGLNRVSEYRNHCSDVIAGFILGTAVALFL 271
Cdd:pfam01569  63 LALLLRRLRKIV-----RVLLALLLLVLALLVGLSRLYLGVHFPSDVLAGALIGILLALLV 118
PLN02250 PLN02250
lipid phosphate phosphatase
 133-296 1.39e-12

lipid phosphate phosphatase


Pssm-ID: 215139  Cd Length: 314  Bit Score: 67.26  E-value: 1.39e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46877066  133 FGLFATDIFVNAGQVVTGHLTPYFLTVCKPnytsaDCQAHHQFINNGNICTGDLEVIEKARRSFPSKHAALSIYSALYAT 212
Cdd:PLN02250 105 FSVLITGVITDAIKDAVGRPRPDFFWRCFP-----DGKGVFHPVTTDVLCTGAKSVIKEGHKSFPSGHTSWSFAGLGFLS 179

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46877066  213 MYITSTIKTKSSR--LAKPVLCLGTLCTAFLTGLNRVSEYRNHCSDVIAGFILGTAVALFlgmCVVHNFkgtqgspskPK 290
Cdd:PLN02250 180 LYLSGKIRVFDRRghVAKLCIVFLPLLVAALVGVSRVDDYWHHWQDVFAGALIGLTVASF---CYLQFF---------PP 247


                 ....*.
gi 46877066  291 PEDPRG 296
Cdd:PLN02250 248 PYDIDG 253
acidPPc smart00014
Acid phosphatase homologues;
173-271 1.36e-10

Acid phosphatase homologues;


Pssm-ID: 214471 [Multi-domain]  Cd Length: 116  Bit Score: 57.74  E-value: 1.36e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46877066    173 HQFINNGNICTGDLEVIEKARRSFPSKHAALSIYSALYATMYItstiktkSSRLAKPVLCLGTLCTAFLTGLNRVSEYRN 252
Cdd:smart00014  24 FFLSIGDACCTPNFLLTLEAGYSFPSGHTAFAFAFALFLLLYL-------PARAGRKLLIFLLLLLALVVGFSRVYLGAH 96

                           90
                   ....*....|....*....
gi 46877066    253 HCSDVIAGFILGTAVALFL 271
Cdd:smart00014  97 WPSDVLAGSLLGILIAAVL 115
PgpB COG0671
Membrane-associated phospholipid phosphatase [Lipid transport and metabolism]; ...
 195-271 2.50e-04

Membrane-associated phospholipid phosphatase [Lipid transport and metabolism]; Membrane-associated phospholipid phosphatase is part of the Pathway/BioSystem: Phospholipid biosynthesis


Pssm-ID: 440435 [Multi-domain]  Cd Length: 189  Bit Score: 41.18  E-value: 2.50e-04
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 46877066 195 SFPSKHAALSIysALYATMYItstiktkssRLAKPVLCLGTLCTAFLTGLNRVseYRN--HCSDVIAGFILGTAVALFL 271
Cdd:COG0671 118 SFPSGHAAAAF--ALALVLAL---------LLPRRWLAALLLALALLVGLSRV--YLGvhYPSDVLAGALLGLAIALLL 183
 
Name Accession Description Interval E-value
PAP2_wunen cd03384
PAP2, wunen subfamily. Most likely a family of membrane associated phosphatidic acid ...
 123-272 6.91e-71

PAP2, wunen subfamily. Most likely a family of membrane associated phosphatidic acid phosphatases. Wunen is a drosophila protein expressed in the central nervous system, which provides repellent activity towards primordial germ cells (PGCs), controls the survival of PGCs and is essential in the migration process of these cells towards the somatic gonadal precursors.


Pssm-ID: 239479  Cd Length: 150  Bit Score: 216.73  E-value: 6.91e-71
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46877066 123 RIIRFTGVFAFGLFATDIFVNAGQVVTGHLTPYFLTVCKPNYTSADCQAHHQFINNGNICTGDLEVIEKARRSFPSKHAA 202
Cdd:cd03384   1 RLYRFVGVFLFGLFATQLLTDLGKYVTGRLRPHFLDVCKPNYTDLTCSLDHQYIADCTCCTGDPDLIREARLSFPSGHAS 80

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46877066 203 LSIYSALYATMYITSTIKTKSSRLAKPVLCLGTLCTAFLTGLNRVSEYRNHCSDVIAGFILGTAVALFLG 272
Cdd:cd03384  81 LSMYAAVFLALYLQARLKLRGSRLLRPLLQFLLLALALYVGLSRISDYKHHWSDVLAGALLGSVIALFLV 150
PAP2_containing_1_like cd03390
PAP2, subfamily similar to human phosphatidic_acid_phosphatase_type_2_domain_containing_1. ...
 59-270 1.14e-17

PAP2, subfamily similar to human phosphatidic_acid_phosphatase_type_2_domain_containing_1. Most likely membrane-associated phosphatidic acid phosphatases. Plant members of this group are constitutively expressed in many tissues and exhibit both diacylglycerol pyrophosphate phosphatase activity as well as phosphatidate (PA) phosphatase activity, they may have a more generic housekeeping role in lipid metabolism.


Pssm-ID: 239484 [Multi-domain]  Cd Length: 193  Bit Score: 79.57  E-value: 1.14e-17
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46877066  59 YPGTEEESF-ITPLVLYCVLaaTPTAIIFIgeISMYFIKSTRESLIAqektILTgeccylnpllrriirftgvFAFGLFA 137
Cdd:cd03390   5 YPFAESETVpTWLLVIISVG--IPLLVIIL--ISLFFRRSLWDLHTS----LLG-------------------LLLSVSL 57

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46877066 138 TDIFVNAGQVVTGHLTPYFLTVCKPNYTSADcqAHHQFINNgnICTGDLEVIEKARRSFPSKHAALSIYSALYATMYITS 217
Cdd:cd03390  58 NGVITNVLKNYAGRPRPDFLARCFPDGGTPS--DTLVGIDI--CCTGDPGVLKEGRKSFPSGHSSFAFAGLGFLSLYLAG 133

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|....*
gi 46877066 218 TIKTKSSR--LAKPVLCLGTLCTAFLTGLNRVSEYRNHCSDVIAGFILGTAVALF 270
Cdd:cd03390 134 KLHIFDPRgsSWRLLLALLPLLLAILVAVSRTRDYRHHFSDVIAGSLIGLIIAYL 188
PAP2_like cd01610
PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, ...
 126-271 4.61e-16

PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid phosphatase, vanadium chloroperoxidases, vanadium bromoperoxidases, and several other mostly uncharacterized subfamilies. Several members of this superfamily have been predicted to be transmembrane proteins.


Pssm-ID: 238813 [Multi-domain]  Cd Length: 122  Bit Score: 73.26  E-value: 4.61e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46877066 126 RFTGVFAFGLFATDIFVNAGQVVTGHLTPYFLTVCKPNYtsadcqahhqfinngnictgDLEVIEKARRSFPSKHAALSI 205
Cdd:cd01610   3 LLALLLLLALLAGLLLTGVLKYLFGRPRPYFLLRCGPDG--------------------DPLLLTEGGYSFPSGHAAFAF 62

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 46877066 206 YSALYATMYITStiktkssRLAKPVLCLGTLCTAFLTGLNRVSEYRNHCSDVIAGFILGTAVALFL 271
Cdd:cd01610  63 ALALFLALLLPR-------RLLRLLLGLLLLLLALLVGLSRVYLGVHYPSDVLAGALLGILVALLV 121
PAP2 pfam01569
PAP2 superfamily; This family includes the enzyme type 2 phosphatidic acid phosphatase (PAP2), ...
 131-271 8.84e-13

PAP2 superfamily; This family includes the enzyme type 2 phosphatidic acid phosphatase (PAP2), Glucose-6-phosphatase EC:3.1.3.9, Phosphatidylglycerophosphatase B EC:3.1.3.27 and bacterial acid phosphatase EC:3.1.3.2. The family also includes a variety of haloperoxidases that function by oxidising halides in the presence of hydrogen peroxide to form the corresponding hypohalous acids.


Pssm-ID: 426329 [Multi-domain]  Cd Length: 124  Bit Score: 64.36  E-value: 8.84e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46877066   131 FAFGLFATDIFVNAGQVVTGHLTPYFLTVCKPNYTSADCQahhqfinngnictgdleviEKARRSFPSKHAALSIYSALY 210
Cdd:pfam01569   2 LLLALALAGLLSSVLKDYFGRPRPFFLLLEGGLVPAPSTL-------------------PGLGYSFPSGHSATAFALALL 62

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 46877066   211 ATMYITSTIKTKssrlaKPVLCLGTLCTAFLTGLNRVSEYRNHCSDVIAGFILGTAVALFL 271
Cdd:pfam01569  63 LALLLRRLRKIV-----RVLLALLLLVLALLVGLSRLYLGVHFPSDVLAGALIGILLALLV 118
PLN02250 PLN02250
lipid phosphate phosphatase
 133-296 1.39e-12

lipid phosphate phosphatase


Pssm-ID: 215139  Cd Length: 314  Bit Score: 67.26  E-value: 1.39e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46877066  133 FGLFATDIFVNAGQVVTGHLTPYFLTVCKPnytsaDCQAHHQFINNGNICTGDLEVIEKARRSFPSKHAALSIYSALYAT 212
Cdd:PLN02250 105 FSVLITGVITDAIKDAVGRPRPDFFWRCFP-----DGKGVFHPVTTDVLCTGAKSVIKEGHKSFPSGHTSWSFAGLGFLS 179

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46877066  213 MYITSTIKTKSSR--LAKPVLCLGTLCTAFLTGLNRVSEYRNHCSDVIAGFILGTAVALFlgmCVVHNFkgtqgspskPK 290
Cdd:PLN02250 180 LYLSGKIRVFDRRghVAKLCIVFLPLLVAALVGVSRVDDYWHHWQDVFAGALIGLTVASF---CYLQFF---------PP 247


                 ....*.
gi 46877066  291 PEDPRG 296
Cdd:PLN02250 248 PYDIDG 253
PLN02715 PLN02715
lipid phosphate phosphatase
 133-321 7.31e-12

lipid phosphate phosphatase


Pssm-ID: 178317 [Multi-domain]  Cd Length: 327  Bit Score: 65.08  E-value: 7.31e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46877066  133 FGLFATDIFVNAGQVVTGHLTPYFLTVCKPnytsaDCQAHHQFINnGNICTGDLEVIEKARRSFPSKHAALSIYSALYAT 212
Cdd:PLN02715 130 FAVLITGVITDSIKVATGRPRPNFYWRCFP-----DGKELYDALG-GVICHGKAAEVKEGHKSFPSGHTSWSFAGLTFLS 203

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46877066  213 MYITSTIK--TKSSRLAKPVLCLGTLCTAFLTGLNRVSEYRNHCSDVIAGFILGTAVALFLGMCVVHNFKGTQG-SP-SK 288
Cdd:PLN02715 204 LYLSGKIKafNGEGHVAKLCLVIFPLLAACLVGISRVDDYWHHWQDVFAGALIGILVAAFCYRQFYPNPYHEEGwGPyAY 283

                        170       180       190
                 ....*....|....*....|....*....|...
gi 46877066  289 PKPEDPRGVPLMAFPRIESpLETLSAQNHSASM 321
Cdd:PLN02715 284 FKAAQERGVPVASSQNGDA-LRAMSLQMDSTSL 315
acidPPc smart00014
Acid phosphatase homologues;
173-271 1.36e-10

Acid phosphatase homologues;


Pssm-ID: 214471 [Multi-domain]  Cd Length: 116  Bit Score: 57.74  E-value: 1.36e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46877066    173 HQFINNGNICTGDLEVIEKARRSFPSKHAALSIYSALYATMYItstiktkSSRLAKPVLCLGTLCTAFLTGLNRVSEYRN 252
Cdd:smart00014  24 FFLSIGDACCTPNFLLTLEAGYSFPSGHTAFAFAFALFLLLYL-------PARAGRKLLIFLLLLLALVVGFSRVYLGAH 96

                           90
                   ....*....|....*....
gi 46877066    253 HCSDVIAGFILGTAVALFL 271
Cdd:smart00014  97 WPSDVLAGSLLGILIAAVL 115
PLN02731 PLN02731
Putative lipid phosphate phosphatase
 133-279 3.61e-09

Putative lipid phosphate phosphatase


Pssm-ID: 178332  Cd Length: 333  Bit Score: 57.35  E-value: 3.61e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46877066  133 FGLFATDIFVNAGQVVTGHLTPYFLTVCKPnytsaDCQAHHQFINNgNICTGDLEVIEKARRSFPSKHAALSIYSALYAT 212
Cdd:PLN02731 124 YSVLVTAVLTDAIKNAVGRPRPDFFWRCFP-----DGKALYDSLGD-VICHGDKSVIREGHKSFPSGHTSWSFSGLGFLS 197

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46877066  213 MYITSTIKTKSSR--LAKPVLCLGTLCTAFLTGLNRVSEYRNHCSDVIAGFILGtavaLF-LGMCVVHNF 279
Cdd:PLN02731 198 LYLSGKIQAFDGKghVAKLCIVILPLLFAALVGISRVDDYWHHWQDVFAGGLLG----LAiSTICYLQFF 263
PAP2_like_2 cd03392
PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This ...
 195-275 1.62e-04

PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase.


Pssm-ID: 239486  Cd Length: 182  Bit Score: 41.83  E-value: 1.62e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46877066 195 SFPSKHAALSIYSALYATMYITSTIKTKSSRLAKPVLCLGTlctAFLTGLNRVseYRN--HCSDVIAGFILGTAVALFLG 272
Cdd:cd03392 102 SFPSGHAMGATVLYGFLAYLLARRLPRRRVRILLLILAAIL---ILLVGLSRL--YLGvhYPSDVLAGWLLGLAWLALLI 176


                ...
gi 46877066 273 MCV 275
Cdd:cd03392 177 LLY 179
PAP2_like_5 cd03394
PAP2_like_5 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This ...
 194-271 2.15e-04

PAP2_like_5 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase.


Pssm-ID: 239488 [Multi-domain]  Cd Length: 106  Bit Score: 40.01  E-value: 2.15e-04
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 46877066 194 RSFPSKHAALSIYSALYAtmyitstiktkSSRLAKPVLCLGTLCTAFLTGLNRVSEYRNHCSDVIAGFILGTAVALFL 271
Cdd:cd03394  39 RSFPSGHTASAFAAATFL-----------QYRYGWRWYGIPAYALASLVGASRVVANRHWLSDVLAGAAIGILVGYLV 105
PgpB COG0671
Membrane-associated phospholipid phosphatase [Lipid transport and metabolism]; ...
 195-271 2.50e-04

Membrane-associated phospholipid phosphatase [Lipid transport and metabolism]; Membrane-associated phospholipid phosphatase is part of the Pathway/BioSystem: Phospholipid biosynthesis


Pssm-ID: 440435 [Multi-domain]  Cd Length: 189  Bit Score: 41.18  E-value: 2.50e-04
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 46877066 195 SFPSKHAALSIysALYATMYItstiktkssRLAKPVLCLGTLCTAFLTGLNRVseYRN--HCSDVIAGFILGTAVALFL 271
Cdd:COG0671 118 SFPSGHAAAAF--ALALVLAL---------LLPRRWLAALLLALALLVGLSRV--YLGvhYPSDVLAGALLGLAIALLL 183
PAP2_like_4 cd03395
PAP2_like_4 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This ...
 195-274 7.12e-03

PAP2_like_4 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase.


Pssm-ID: 239489  Cd Length: 177  Bit Score: 36.86  E-value: 7.12e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 46877066 195 SFPSKHAALSIYSALYATMYItstiktkSSRLAKPVLclgtLCTAFLTGLNRVSEYRNHCSDVIAGFILGTAVALFLGMC 274
Cdd:cd03395 105 SFASSHAANSFALALFIWLFF-------RRGLFSPVL----LLWALLVGYSRVYVGVHYPGDVIAGALIGIISGLLFYLL 173
PAP2_containing_2_like cd03391
PAP2, subfamily similar to human phosphatidic_acid_phosphatase_type_2_domain_containing_2. ...
 195-272 8.81e-03

PAP2, subfamily similar to human phosphatidic_acid_phosphatase_type_2_domain_containing_2. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to eukaryota, lacks functional characterization and may act as a membrane-associated phosphatidic acid phosphatase.


Pssm-ID: 239485 [Multi-domain]  Cd Length: 159  Bit Score: 36.53  E-value: 8.81e-03
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 46877066 195 SFPSKHAAlsiYSALYATMYITSTIktkssrLAKPVLCLGTLcTAFLTGLNRVSEYRNHCSDVIAGFILGTAVALFLG 272
Cdd:cd03391  92 SFPSGHAS---RAAFVARFLLNHLV------LAVPLRVLLVL-WATVVGISRVLLGRHHVLDVLAGAFLGYLEALLVE 159
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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