![](files/infoQ.gif)
hemojuvelin isoform c [Homo sapiens]
RGM_C domain-containing protein( domain architecture ID 10534809)
RGM_C domain-containing protein
List of domain hits
![](files/help.png)
Name | Accession | Description | Interval | E-value | ||||
RGM_C | pfam06534 | Repulsive guidance molecule (RGM) C-terminus; This family consists of several mammalian and ... |
4-163 | 1.59e-84 | ||||
Repulsive guidance molecule (RGM) C-terminus; This family consists of several mammalian and one bird sequence from Gallus gallus (Chicken). This family represents the C-terminal region of several sequences but in others it represents the full protein. All of the mammalian proteins are hypothetical and have no known function but Swiss:Q8JG54 from the chicken is annotated as being a repulsive guidance molecule (RGM). RGM is a GPI-linked axon guidance molecule of the retinotectal system. RGM is repulsive for a subset of axons, those from the temporal half of the retina. Temporal retinal axons invade the anterior optic tectum in a superficial layer, and encounter RGM expressed in a gradient with increasing concentration along the anterior-posterior axis. Temporal axons are able to receive posterior-dependent information by sensing gradients or concentrations of guidance cues. Thus, RGM is likely to provide positional information for temporal axons invading the optic tectum in the stratum opticum. : Pssm-ID: 461939 Cd Length: 171 Bit Score: 247.15 E-value: 1.59e-84
|
||||||||
Name | Accession | Description | Interval | E-value | ||||
RGM_C | pfam06534 | Repulsive guidance molecule (RGM) C-terminus; This family consists of several mammalian and ... |
4-163 | 1.59e-84 | ||||
Repulsive guidance molecule (RGM) C-terminus; This family consists of several mammalian and one bird sequence from Gallus gallus (Chicken). This family represents the C-terminal region of several sequences but in others it represents the full protein. All of the mammalian proteins are hypothetical and have no known function but Swiss:Q8JG54 from the chicken is annotated as being a repulsive guidance molecule (RGM). RGM is a GPI-linked axon guidance molecule of the retinotectal system. RGM is repulsive for a subset of axons, those from the temporal half of the retina. Temporal retinal axons invade the anterior optic tectum in a superficial layer, and encounter RGM expressed in a gradient with increasing concentration along the anterior-posterior axis. Temporal axons are able to receive posterior-dependent information by sensing gradients or concentrations of guidance cues. Thus, RGM is likely to provide positional information for temporal axons invading the optic tectum in the stratum opticum. Pssm-ID: 461939 Cd Length: 171 Bit Score: 247.15 E-value: 1.59e-84
|
||||||||
Name | Accession | Description | Interval | E-value | ||||
RGM_C | pfam06534 | Repulsive guidance molecule (RGM) C-terminus; This family consists of several mammalian and ... |
4-163 | 1.59e-84 | ||||
Repulsive guidance molecule (RGM) C-terminus; This family consists of several mammalian and one bird sequence from Gallus gallus (Chicken). This family represents the C-terminal region of several sequences but in others it represents the full protein. All of the mammalian proteins are hypothetical and have no known function but Swiss:Q8JG54 from the chicken is annotated as being a repulsive guidance molecule (RGM). RGM is a GPI-linked axon guidance molecule of the retinotectal system. RGM is repulsive for a subset of axons, those from the temporal half of the retina. Temporal retinal axons invade the anterior optic tectum in a superficial layer, and encounter RGM expressed in a gradient with increasing concentration along the anterior-posterior axis. Temporal axons are able to receive posterior-dependent information by sensing gradients or concentrations of guidance cues. Thus, RGM is likely to provide positional information for temporal axons invading the optic tectum in the stratum opticum. Pssm-ID: 461939 Cd Length: 171 Bit Score: 247.15 E-value: 1.59e-84
|
||||||||
Blast search parameters | ||||
|