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Conserved domains on  [gi|528504594|ref|XP_005158264|]
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selenium-binding protein 1 isoform X1 [Danio rerio]

Protein Classification

selenium-binding family protein( domain architecture ID 10529529)

selenium-binding family protein similar to human methanethiol oxidase (also called selenium-binding protein 1 or 56 kDa selenium-binding protein) that catalyzes the oxidation of methanethiol, an organosulfur compound known to be produced in substantial amounts by gut bacteria, and may be involved in intra-Golgi protein transport

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SBP56 pfam05694
56kDa selenium binding protein (SBP56); This family consists of several eukaryotic selenium ...
 8-473 0e+00

56kDa selenium binding protein (SBP56); This family consists of several eukaryotic selenium binding proteins as well as three sequences from archaea. The exact function of this protein is unknown although it is thought that SBP56 participates in late stages of intra-Golgi protein transport. The Lotus japonicus homolog of SBP56, LjSBP is thought to have more than one physiological role and can be implicated in controlling the oxidation/reduction status of target proteins, in vesicular Golgi transport.


:

Pssm-ID: 461716  Cd Length: 453  Bit Score: 877.41  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528504594    8 CGPGYKTPLDAMKGPREEIVYLPCIYRNTDIQKPDYLATVDINPQSPNFCKVIHRLPMPNLKDELHHSGWNACSSCFDDP 87
Cdd:pfam05694   3 PGPGYASPLDAMKAPREKLAYVAALYPGTGINKPDYLATVDVDPKSPTYGQVVHRLPMPNIGDELHHFGWNACSSCHGDP 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528504594   88 SKRRNRLILPSLISSRIYVVDVGTDPRAPRLHKTVEPTDLFWKCGLANPHTSHCLGSGQIMISTMGDPSGNGKGGFVLLD 167
Cdd:pfam05694  83 SKERRYLIVPGLRSSRIYIVDTKTDPRAPRLVKVIEPEEVAEKTGYSRPHTVHCLPDGEIYISALGDADGNGPGGFLLLD 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528504594  168 GETFEVIGNWEQPGDAAPFGYDFWYQPRHNVMISTEWGAPKALGNGFNPADVKAGHYGQRLHVWDWTTHKRIQTLDLGEE 247
Cdd:pfam05694 163 HETFEVKGRWEKDRGPQLFGYDFWYQPRHNVMISSEWGAPNTFEDGFNPEDLEDGLYGHRLHFWDWSTRKHKQTIDLGEE 242

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528504594  248 GAIPLEVRFLHDPAAAEGFVGCALQSTVFRFYKTPKGDWAAEKVIKVPSKKVEGWALPDMPGLITDILISLDDRFLYFSN 327
Cdd:pfam05694 243 GQMPLELRFLHDPTKAHGFVGCALSSSIWRWYKNDGGKWAAEKVIEIPAEPVEGWILPPMPPLVTDILISLDDRFLYVSC 322

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528504594  328 WLHGDIRQYDITDRKNPRMVGQVFLGGSVLKDGPVKVledkeldsqptprilKGKRVQGGPQMLQLSLDGKRLYVTTSLY 407
Cdd:pfam05694 323 WLHGDLRQYDISDPFNPRLTGQVRLGGIIRRAPHPAV---------------KGRRLNGGPQMVQLSLDGKRLYVTNSLY 387

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 528504594  408 SAWDKQFYPDLIKEGSVMMQIDVNTDTGGLKLNENFLVDFGAEPEGPALAHELRYPGGDCTSDIWL 473
Cdd:pfam05694 388 SSWDDQFYPDGVKKGGWMLKIDVDPETGGLSLNPNFFVDFGKEPDGPARAHEMRYPGGDCSSDIWC 453
 
Name Accession Description Interval E-value
SBP56 pfam05694
56kDa selenium binding protein (SBP56); This family consists of several eukaryotic selenium ...
 8-473 0e+00

56kDa selenium binding protein (SBP56); This family consists of several eukaryotic selenium binding proteins as well as three sequences from archaea. The exact function of this protein is unknown although it is thought that SBP56 participates in late stages of intra-Golgi protein transport. The Lotus japonicus homolog of SBP56, LjSBP is thought to have more than one physiological role and can be implicated in controlling the oxidation/reduction status of target proteins, in vesicular Golgi transport.


Pssm-ID: 461716  Cd Length: 453  Bit Score: 877.41  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528504594    8 CGPGYKTPLDAMKGPREEIVYLPCIYRNTDIQKPDYLATVDINPQSPNFCKVIHRLPMPNLKDELHHSGWNACSSCFDDP 87
Cdd:pfam05694   3 PGPGYASPLDAMKAPREKLAYVAALYPGTGINKPDYLATVDVDPKSPTYGQVVHRLPMPNIGDELHHFGWNACSSCHGDP 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528504594   88 SKRRNRLILPSLISSRIYVVDVGTDPRAPRLHKTVEPTDLFWKCGLANPHTSHCLGSGQIMISTMGDPSGNGKGGFVLLD 167
Cdd:pfam05694  83 SKERRYLIVPGLRSSRIYIVDTKTDPRAPRLVKVIEPEEVAEKTGYSRPHTVHCLPDGEIYISALGDADGNGPGGFLLLD 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528504594  168 GETFEVIGNWEQPGDAAPFGYDFWYQPRHNVMISTEWGAPKALGNGFNPADVKAGHYGQRLHVWDWTTHKRIQTLDLGEE 247
Cdd:pfam05694 163 HETFEVKGRWEKDRGPQLFGYDFWYQPRHNVMISSEWGAPNTFEDGFNPEDLEDGLYGHRLHFWDWSTRKHKQTIDLGEE 242

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528504594  248 GAIPLEVRFLHDPAAAEGFVGCALQSTVFRFYKTPKGDWAAEKVIKVPSKKVEGWALPDMPGLITDILISLDDRFLYFSN 327
Cdd:pfam05694 243 GQMPLELRFLHDPTKAHGFVGCALSSSIWRWYKNDGGKWAAEKVIEIPAEPVEGWILPPMPPLVTDILISLDDRFLYVSC 322

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528504594  328 WLHGDIRQYDITDRKNPRMVGQVFLGGSVLKDGPVKVledkeldsqptprilKGKRVQGGPQMLQLSLDGKRLYVTTSLY 407
Cdd:pfam05694 323 WLHGDLRQYDISDPFNPRLTGQVRLGGIIRRAPHPAV---------------KGRRLNGGPQMVQLSLDGKRLYVTNSLY 387

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 528504594  408 SAWDKQFYPDLIKEGSVMMQIDVNTDTGGLKLNENFLVDFGAEPEGPALAHELRYPGGDCTSDIWL 473
Cdd:pfam05694 388 SSWDDQFYPDGVKKGGWMLKIDVDPETGGLSLNPNFFVDFGKEPDGPARAHEMRYPGGDCSSDIWC 453
YncE COG3391
DNA-binding beta-propeller fold protein YncE [General function prediction only];
221-403 8.57e-04

DNA-binding beta-propeller fold protein YncE [General function prediction only];


Pssm-ID: 442618 [Multi-domain]  Cd Length: 237  Bit Score: 40.83  E-value: 8.57e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528504594 221 AGHYGQRLHVWDWTTHKRIQTLDLGEEgaiPLEVRFlhDPAAAEGFVGCALQSTVFRFyktpkgDWAAEKVIKVpskkve 300
Cdd:COG3391   85 ANSGSGRVSVIDLATGKVVATIPVGGG---PRGLAV--DPDGGRLYVADSGNGRVSVI------DTATGKVVAT------ 147

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528504594 301 gWALPDMPgliTDILISLDDRFLYFSNWLHGDIRQY-DITDRKNPRMVGQVFLGgsvlkdgpvkvledkeldsqptpril 379
Cdd:COG3391  148 -IPVGAGP---HGIAVDPDGKRLYVANSGSNTVSVIvSVIDTATGKVVATIPVG-------------------------- 197

                        170       180
                 ....*....|....*....|....
gi 528504594 380 kgkrvqGGPQMLQLSLDGKRLYVT 403
Cdd:COG3391  198 ------GGPVGVAVSPDGRRLYVA 215
 
Name Accession Description Interval E-value
SBP56 pfam05694
56kDa selenium binding protein (SBP56); This family consists of several eukaryotic selenium ...
 8-473 0e+00

56kDa selenium binding protein (SBP56); This family consists of several eukaryotic selenium binding proteins as well as three sequences from archaea. The exact function of this protein is unknown although it is thought that SBP56 participates in late stages of intra-Golgi protein transport. The Lotus japonicus homolog of SBP56, LjSBP is thought to have more than one physiological role and can be implicated in controlling the oxidation/reduction status of target proteins, in vesicular Golgi transport.


Pssm-ID: 461716  Cd Length: 453  Bit Score: 877.41  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528504594    8 CGPGYKTPLDAMKGPREEIVYLPCIYRNTDIQKPDYLATVDINPQSPNFCKVIHRLPMPNLKDELHHSGWNACSSCFDDP 87
Cdd:pfam05694   3 PGPGYASPLDAMKAPREKLAYVAALYPGTGINKPDYLATVDVDPKSPTYGQVVHRLPMPNIGDELHHFGWNACSSCHGDP 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528504594   88 SKRRNRLILPSLISSRIYVVDVGTDPRAPRLHKTVEPTDLFWKCGLANPHTSHCLGSGQIMISTMGDPSGNGKGGFVLLD 167
Cdd:pfam05694  83 SKERRYLIVPGLRSSRIYIVDTKTDPRAPRLVKVIEPEEVAEKTGYSRPHTVHCLPDGEIYISALGDADGNGPGGFLLLD 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528504594  168 GETFEVIGNWEQPGDAAPFGYDFWYQPRHNVMISTEWGAPKALGNGFNPADVKAGHYGQRLHVWDWTTHKRIQTLDLGEE 247
Cdd:pfam05694 163 HETFEVKGRWEKDRGPQLFGYDFWYQPRHNVMISSEWGAPNTFEDGFNPEDLEDGLYGHRLHFWDWSTRKHKQTIDLGEE 242

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528504594  248 GAIPLEVRFLHDPAAAEGFVGCALQSTVFRFYKTPKGDWAAEKVIKVPSKKVEGWALPDMPGLITDILISLDDRFLYFSN 327
Cdd:pfam05694 243 GQMPLELRFLHDPTKAHGFVGCALSSSIWRWYKNDGGKWAAEKVIEIPAEPVEGWILPPMPPLVTDILISLDDRFLYVSC 322

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528504594  328 WLHGDIRQYDITDRKNPRMVGQVFLGGSVLKDGPVKVledkeldsqptprilKGKRVQGGPQMLQLSLDGKRLYVTTSLY 407
Cdd:pfam05694 323 WLHGDLRQYDISDPFNPRLTGQVRLGGIIRRAPHPAV---------------KGRRLNGGPQMVQLSLDGKRLYVTNSLY 387

                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 528504594  408 SAWDKQFYPDLIKEGSVMMQIDVNTDTGGLKLNENFLVDFGAEPEGPALAHELRYPGGDCTSDIWL 473
Cdd:pfam05694 388 SSWDDQFYPDGVKKGGWMLKIDVDPETGGLSLNPNFFVDFGKEPDGPARAHEMRYPGGDCSSDIWC 453
YncE COG3391
DNA-binding beta-propeller fold protein YncE [General function prediction only];
221-403 8.57e-04

DNA-binding beta-propeller fold protein YncE [General function prediction only];


Pssm-ID: 442618 [Multi-domain]  Cd Length: 237  Bit Score: 40.83  E-value: 8.57e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528504594 221 AGHYGQRLHVWDWTTHKRIQTLDLGEEgaiPLEVRFlhDPAAAEGFVGCALQSTVFRFyktpkgDWAAEKVIKVpskkve 300
Cdd:COG3391   85 ANSGSGRVSVIDLATGKVVATIPVGGG---PRGLAV--DPDGGRLYVADSGNGRVSVI------DTATGKVVAT------ 147

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528504594 301 gWALPDMPgliTDILISLDDRFLYFSNWLHGDIRQY-DITDRKNPRMVGQVFLGgsvlkdgpvkvledkeldsqptpril 379
Cdd:COG3391  148 -IPVGAGP---HGIAVDPDGKRLYVANSGSNTVSVIvSVIDTATGKVVATIPVG-------------------------- 197

                        170       180
                 ....*....|....*....|....
gi 528504594 380 kgkrvqGGPQMLQLSLDGKRLYVT 403
Cdd:COG3391  198 ------GGPVGVAVSPDGRRLYVA 215
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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