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E3 ubiquitin-protein ligase TRIP12 isoform X3 [Danio rerio]
Protein Classification
E3 ubiquitin-protein ligase TRIP12 family protein ( domain architecture ID 13359941 )
E3 ubiquitin-protein ligase TRIP12 (thyroid hormone receptor interactor 12) family protein is involved in a broad range of physiological processes such as mouse embryogenesis; TRIP12 displays a HECT domain, a WW (tryptophan-tryptophan) protein-protein interaction motif and an ARM domain (armadillo/beta-catenin-like repeats)
List of domain hits
Name
Accession
Description
Interval
E-value
HECTc
cd00078 HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It ...
1651-2052
1.77e-123
HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ubiquitin molecules to the end of growing ubiquitin chains.
Pssm-ID: 238033 [Multi-domain]
Cd Length: 352
Bit Score: 393.47
E-value: 1.77e-123
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528508457 1651 K R T IN RD EL L KQ A ESVMQDLG SS -- RAM LE IQYEN E V G TG - L G P T Q EF YA LVS Q EL QRADL GL W R GEE vtlsnpkvgsqe 1727
Cdd:cd00078 2 K I T VR RD RI L ED A LRQLSKVS SS dl KKV LE VEFVG E E G ID a G G V T R EF FT LVS K EL FNPSY GL F R YTP ------------ 69
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528508457 1728 gtkym FS S RG L FAV P FGRTTK pahia KIKMK FRFLG K L MA KA IMDF RLLDLP LGLP FYK WM L RH es SI S SH DL VNI DP GV 1807
Cdd:cd00078 70 ----- DD S GL L YPN P SSFADE ----- DHLKL FRFLG R L LG KA LYEG RLLDLP FSRA FYK KL L GK -- PL S LE DL EEL DP EL 137
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528508457 1808 A KS IQH L ediirqkkrieqdrshtretlqqales L NMN G c SVE DL G L D FT ------ LP G FPNI ELK K GG K D V PVT IH N L E 1881
Cdd:cd00078 138 Y KS LKE L --------------------------- L DND G - DED DL E L T FT ieldss FG G AVTV ELK P GG R D I PVT NE N K E 189
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528508457 1882 D Y LR L V V YWT LN E G VLR Q F E S FR E GF ES V F P LHH L QY F Y PEEL DQ L L CG sk SE SW D VKT L MECCRPDH GY TH DS RAVRFL 1961
Cdd:cd00078 190 E Y VD L Y V DYR LN K G IEE Q V E A FR D GF SE V I P EEL L SL F T PEEL EL L I CG -- SE DI D LED L KKNTEYKG GY SS DS PTIQWF 267
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528508457 1962 F EVL S SF DA E QQRL FLQFVTGS P RLPVGGF RS LNP PL TI V R K tfest EN PDD F LP SVM TC V N Y LKLP D YSS I EI M REKLL 2041
Cdd:cd00078 268 W EVL E SF TN E ERKK FLQFVTGS S RLPVGGF AD LNP KF TI R R V ----- GS PDD R LP TAH TC F N L LKLP P YSS K EI L REKLL 342
410
....*....|.
gi 528508457 2042 I A AR EG q QS F H 2052
Cdd:cd00078 343 Y A IN EG - AG F G 352
WWE
pfam02825 WWE domain; The WWE domain is named after three of its conserved residues and is predicted to ...
802-865
1.26e-25
WWE domain; The WWE domain is named after three of its conserved residues and is predicted to mediate specific protein- protein interactions in ubiquitin and ADP ribose conjugation systems.
Pssm-ID: 460715 [Multi-domain]
Cd Length: 66
Bit Score: 101.60
E-value: 1.26e-25
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 528508457 802 I W Q W R DD R G L WHPY NRID S RI IE T A H Q N G EDEIS LS -- T L G RV YTIDF N SM Q Q I N E DTGT A R AIQ R 865
Cdd:pfam02825 1 V W E W E DD N G G WHPY DPEV S SL IE E A Y Q K G KPSVD LS it T A G FP YTIDF K SM T Q T N K DTGT T R PVR R 66
Metaviral_G super family
cl26626 Metaviral_G glycoprotein; This is a viral attachment glycoprotein from region G of metaviruses. ...
48-170
2.49e-06
Metaviral_G glycoprotein; This is a viral attachment glycoprotein from region G of metaviruses. It is high in serine and threonine suggesting it is highly glycosylated.
pfam09595 :Pssm-ID: 462833 [Multi-domain]
Cd Length: 183
Bit Score: 49.95
E-value: 2.49e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528508457 48 P D LEAAGTSGQ Q GRR E GSS - TR A L K RS - S V SE PNIT fs PS P AKRPKVVSSHFSDSSA sgp S A PAIS P EVT EP RKA P ASVS 125
Cdd:pfam09595 51 I D ININKQHPE Q EHH E NPP l NE A A K EA p S E SE DAPD -- ID P NNQHPSQDRSEAPPLE --- P A AKTK P SEH EP ANP P DASN 125
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 528508457 126 TK S KKRRLA A EPAP AR ALS K K S S - SYPG PS G A S S TP S QK R KKAD A T 170
Cdd:pfam09595 126 RL S PPDAST A AIRE AR TFR K P S T g KRNN PS S A Q S DQ S PP R ANHE A I 171
PHA03307 super family
cl33723 transcriptional regulator ICP4; Provisional
59-440
2.56e-04
transcriptional regulator ICP4; Provisional
PHA03307 :Pssm-ID: 223039 [Multi-domain]
Cd Length: 1352
Bit Score: 46.32
E-value: 2.56e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528508457 59 QGR REGS S T RA l KR SS VSE P NI T FS P - SP AKR P - KVV S SHFSDSSAS GP SAP A IS P EVTEPRK A P AS VSTK S kkrrlaae 136
Cdd:PHA03307 99 SPA REGS P T PP - GP SS PDP P PP T PP P a SP PPS P a PDL S EMLRPVGSP GP PPA A SP P AAGASPA A V AS DAAS S -------- 169
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528508457 137 PAP A RA LS KKSSSYPG PS GASST P SQKRKK A D A TLLSSSS SS SLPS S S S AAG P L P P RS E A SR A akptklasksaasakag 216
Cdd:PHA03307 170 RQA A LP LS SPEETARA PS SPPAE P PPSTPP A A A SPRPPRR SS PISA S A S SPA P A P G RS A A DD A ----------------- 232
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528508457 217 c STVTDS SSSS A SS SSSSS ssssaat GT N S C A --- P QGAR L KQGKDQSKARRSR S ASSPSPRR SS RDK E Q S KAAGS S KFD 293
Cdd:PHA03307 233 - GASSSD SSSS E SS GCGWG ------- PE N E C P lpr P APIT L PTRIWEASGWNGP S SRPGPASS SS SPR E R S PSPSP S SPG 304
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528508457 294 WASRFN S KVNLPKPKL S LPG S AKAET SS KPGPS G LQAKLASLRKSTKKR S ES PP AEL PS CR R STRQKTTGSCASTSRR G S 373
Cdd:PHA03307 305 SGPAPS S PRASSSSSS S RES S SSSTS SS SESSR G AAVSPGPSPSRSPSP S RP PP PAD PS SP R KRPRPSRAPSSPAASA G R 384
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 528508457 374 GLGK R GA A EARRQEKMA D SDNNQDG ans SAA R TEETPQ GA SASSSV A GAVGM T T SGE S -- E S DDSEM GR 440
Cdd:PHA03307 385 PTRR R AR A AVAGRARRR D ATGRFPA --- GRP R PSPLDA GA ASGAFY A RYPLL T P SGE P wp G S PPPPP GR 450
SRP1 super family
cl34886 Karyopherin (importin) alpha [Intracellular trafficking and secretion];
480-671
1.88e-03
Karyopherin (importin) alpha [Intracellular trafficking and secretion];
COG5064 :Pssm-ID: 227396 [Multi-domain]
Cd Length: 526
Bit Score: 43.34
E-value: 1.88e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528508457 480 QL L Q G L QAT g D ES QQLQA AIEMCQ LL VMGNEETLGGFPVKS VVP ALITLLQ m E HNF D IMN - H A SR ALT YMMEALPRSSA V 558
Cdd:COG5064 75 QL T Q Q L FSD - D IE QQLQA VYKFRK LL SKETSPPIQPVIDAG VVP RFVEFMD - E IQR D MLQ f E A AW ALT NIASGTTQQTK V 152
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528508457 559 VVD -- A I P V F LEK L QVIQ f I DV A EQA LT AL EML --- S RRHSKAI LQ A G G L ADC L LY L EFFS I NAQ -- RNA LAIAA N C C QS 631
Cdd:COG5064 153 VVD ag A V P L F IQL L SSTE - D DV R EQA VW AL GNI agd S EGCRDYV LQ C G A L EPL L GL L LSSA I HIS ml RNA TWTLS N L C RG 231
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 528508457 632 IT P D - EFHFVADS LP L L TQRLTHQ D KKSVEST C LCFAR L V D 671
Cdd:COG5064 232 KN P P p DWSNISQA LP I L AKLIYSR D PEVLVDA C WAISY L S D 272
Name
Accession
Description
Interval
E-value
HECTc
cd00078 HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It ...
1651-2052
1.77e-123
HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ubiquitin molecules to the end of growing ubiquitin chains.
Pssm-ID: 238033 [Multi-domain]
Cd Length: 352
Bit Score: 393.47
E-value: 1.77e-123
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528508457 1651 K R T IN RD EL L KQ A ESVMQDLG SS -- RAM LE IQYEN E V G TG - L G P T Q EF YA LVS Q EL QRADL GL W R GEE vtlsnpkvgsqe 1727
Cdd:cd00078 2 K I T VR RD RI L ED A LRQLSKVS SS dl KKV LE VEFVG E E G ID a G G V T R EF FT LVS K EL FNPSY GL F R YTP ------------ 69
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528508457 1728 gtkym FS S RG L FAV P FGRTTK pahia KIKMK FRFLG K L MA KA IMDF RLLDLP LGLP FYK WM L RH es SI S SH DL VNI DP GV 1807
Cdd:cd00078 70 ----- DD S GL L YPN P SSFADE ----- DHLKL FRFLG R L LG KA LYEG RLLDLP FSRA FYK KL L GK -- PL S LE DL EEL DP EL 137
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528508457 1808 A KS IQH L ediirqkkrieqdrshtretlqqales L NMN G c SVE DL G L D FT ------ LP G FPNI ELK K GG K D V PVT IH N L E 1881
Cdd:cd00078 138 Y KS LKE L --------------------------- L DND G - DED DL E L T FT ieldss FG G AVTV ELK P GG R D I PVT NE N K E 189
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528508457 1882 D Y LR L V V YWT LN E G VLR Q F E S FR E GF ES V F P LHH L QY F Y PEEL DQ L L CG sk SE SW D VKT L MECCRPDH GY TH DS RAVRFL 1961
Cdd:cd00078 190 E Y VD L Y V DYR LN K G IEE Q V E A FR D GF SE V I P EEL L SL F T PEEL EL L I CG -- SE DI D LED L KKNTEYKG GY SS DS PTIQWF 267
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528508457 1962 F EVL S SF DA E QQRL FLQFVTGS P RLPVGGF RS LNP PL TI V R K tfest EN PDD F LP SVM TC V N Y LKLP D YSS I EI M REKLL 2041
Cdd:cd00078 268 W EVL E SF TN E ERKK FLQFVTGS S RLPVGGF AD LNP KF TI R R V ----- GS PDD R LP TAH TC F N L LKLP P YSS K EI L REKLL 342
410
....*....|.
gi 528508457 2042 I A AR EG q QS F H 2052
Cdd:cd00078 343 Y A IN EG - AG F G 352
HECTc
smart00119 Domain Homologous to E6-AP Carboxyl Terminus with; E3 ubiquitin-protein ligases. Can bind to ...
1669-2048
5.02e-119
Domain Homologous to E6-AP Carboxyl Terminus with; E3 ubiquitin-protein ligases. Can bind to E2 enzymes.
Pssm-ID: 214523
Cd Length: 328
Bit Score: 379.66
E-value: 5.02e-119
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528508457 1669 DL GSSR am LEI QY E N E V G - T G L G P T Q EF YA L V S Q EL QRA D L GL W R geevtlsnpkvgsqegtk Y MFSSRG L FAV P FGRTT 1747
Cdd:smart00119 1 DL KKRV -- LEI EF E G E E G l D G G G V T R EF FF L L S K EL FNP D Y GL F R ------------------ Y SPNDYL L YPN P RSGFA 60
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528508457 1748 KPA H I akik MK FRF L G KLMA KA IM D F RLLDL PLGL PFYK WM L RH es SISS HDL VNI DP GVA KS IQH L ediirqkk RIEQ D 1827
Cdd:smart00119 61 NEE H L ---- SY FRF I G RVLG KA LY D N RLLDL FFAR PFYK KL L GK -- PVTL HDL ESL DP ELY KS LKW L -------- LLNN D 126
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528508457 1828 R S htretlqqal E S L NMN gcsv EDLG L DFTLPGFPNI ELK K GG KDV PVT IH N LED Y LR LV VYWT LN E G VLR Q F E S FREGF 1907
Cdd:smart00119 127 T S ---------- E E L DLT ---- FSIV L TSEFGQVKVV ELK P GG SNI PVT EE N KKE Y VH LV IEYR LN K G IEK Q L E A FREGF 192
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528508457 1908 ES V F P LHH L QY F Y PEEL DQ L L CGS ks ESW DV KT L MECCRPDH GY THD S RAVRFLF EV LS SF DA E QQ R LF LQFVTGS P RLP 1987
Cdd:smart00119 193 SE V I P ENL L KL F D PEEL EL L I CGS -- PEI DV DD L KSNTEYKG GY SAN S QTIKWFW EV VE SF TN E ER R KL LQFVTGS S RLP 270
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 528508457 1988 VGGF RS L N P PL TI VRKTFE stenp D DF LP SVM TC V N Y LKLP D YSS I EI M REKLL I A AR EG Q 2048
Cdd:smart00119 271 VGGF AA L S P KF TI RKAGSD ----- D ER LP TAH TC F N R LKLP P YSS K EI L REKLL L A IN EG K 326
HECT
pfam00632 HECT-domain (ubiquitin-transferase); The name HECT comes from Homologous to the E6-AP Carboxyl ...
1698-2054
8.77e-103
HECT-domain (ubiquitin-transferase); The name HECT comes from Homologous to the E6-AP Carboxyl Terminus.
Pssm-ID: 459880
Cd Length: 304
Bit Score: 332.27
E-value: 8.77e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528508457 1698 L V S Q EL QRADL GL WR geevtlsnpk VGSQEGTK Y M F S srglfav P FGRTTKPAHIAK ikm K F R FLGKL MA KAI MDFR LLD 1777
Cdd:pfam00632 2 L L S K EL FDPNY GL FE ---------- YETEDDRT Y W F N ------- P SSSESPDLELLD --- Y F K FLGKL LG KAI YNGI LLD 61
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528508457 1778 LP LGLP FYK WM L R he SSISSH DL VN IDP GVA KS IQH L ediirqkkrieqdrshtretlqqales LNM NGCSV EDLGL D FT 1857
Cdd:pfam00632 62 LP FPPF FYK KL L G -- EPLTLE DL ES IDP ELY KS LKS L --------------------------- LNM DNDDD EDLGL T FT 112
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528508457 1858 L P G F --- PN IEL KKG G KDV PVT IH N L E D Y L RL V V YWT LN EGVLR Q F E S FR E GF E SV F P LHH L QY F Y PEEL DQ L L CG sk S E 1934
Cdd:pfam00632 113 I P V F ges KT IEL IPN G RNI PVT NE N K E E Y I RL Y V DYR LN KSIEP Q L E A FR K GF Y SV I P KEA L SL F T PEEL EL L I CG -- S P 190
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528508457 1935 SW DV KT L MECCRP D H GYT HD S RAVRFLF E V L SS F DA EQ Q RLFL Q FVTGS P RLPVGGF R SL n P PL TIVRK TF este NP DD F 2014
Cdd:pfam00632 191 EI DV ED L KKNTEY D G GYT KN S PTIQWFW E I L EE F SP EQ R RLFL K FVTGS S RLPVGGF K SL - P KF TIVRK GG ---- DD DD R 265
330 340 350 360
....*....|....*....|....*....|....*....|
gi 528508457 2015 LP SVM TC V N Y LKLPDYSS I EI MR EKLLIA AR EG q QS F H LS 2054
Cdd:pfam00632 266 LP TAH TC F N R LKLPDYSS K EI LK EKLLIA IE EG - EG F G LS 304
HUL4
COG5021 Ubiquitin-protein ligase [Posttranslational modification, protein turnover, chaperones];
1564-2053
6.65e-81
Ubiquitin-protein ligase [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 227354 [Multi-domain]
Cd Length: 872
Bit Score: 287.43
E-value: 6.65e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528508457 1564 FINSKLTAKAN R QLQDPLVIMTGNIPTWLTEL G ktc P FFFPFD TR QMLF Y VTA F D r DRAMQR L LDTNPEINQSD S QDSRV 1643
Cdd:COG5021 413 TYEDLRREQLG R ESDESFYVASNVQQQRASRE G --- P LLSGWK TR LNNL Y RFY F V - EHRKKT L TKNDSRLGSFI S LNKLD 488
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528508457 1644 AP R LDRK KR TINRDE L LKQ A ESVM -- QDLGSS R AM ---- LEIQYEN E V G TG L GP T Q E FYALVSQEL qra D L G LWRG E EVT 1717
Cdd:COG5021 489 IR R IKED KR RKLFYS L KQK A KIFD py LHIKVR R DR vfed SYREIMD E S G DD L KK T L E IEFVGEEGI --- D A G GLTR E WLF 565
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528508457 1718 L SNPKVGSQEGTKYMFSSRG L FAV P FGRT -- TK P A H IAK ikmk F R FLG KLMA KAI M D F R L LD LPLGLP FYK WM L RH es SI 1795
Cdd:COG5021 566 L LSKEMFNPDYGLFEYITED L YTL P INPL ss IN P E H LSY ---- F K FLG RVIG KAI Y D S R I LD VQFSKA FYK KL L GK -- PV 639
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528508457 1796 S SH DL VNI DP GVAK S IQH L EDIIRQKKRIE qdrshtretlqqales L NM ngc S VED LGLDFTLP gfpn I EL KKG G KDVP V 1875
Cdd:COG5021 640 S LV DL ESL DP ELYR S LVW L LNNDIDETILD ---------------- L TF --- T VED DSFGESRT ---- V EL IPN G RNIS V 696
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528508457 1876 T IH N LED Y LRL VV YWT LN EG V LR QF ES F RE GF ESVF P LHH LQ Y F YPE EL DQ L LC G S k S E SW D VKTLMECCR p D HGYT H DS 1955
Cdd:COG5021 697 T NE N KKE Y VKK VV DYK LN KR V EK QF SA F KS GF SEII P PDL LQ I F DES EL EL L IG G I - P E DI D IDDWKSNTA - Y HGYT E DS 774
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528508457 1956 RAVRFLF E VL S S FD A E QQRLF LQFVTG SP R L P VG GF RS L NPPLTIVRK T F E STENP DD F LPS VM TC V N Y LKLP D YSS I E I 2035
Cdd:COG5021 775 PIIVWFW E II S E FD F E ERAKL LQFVTG TS R I P IN GF KD L QGSDGVRKF T I E KGGTD DD R LPS AH TC F N R LKLP E YSS K E K 854
490
....*....|....*...
gi 528508457 2036 M R E KLL I A AR EG QQSFH L 2053
Cdd:COG5021 855 L R S KLL T A IN EG AGFGL L 872
WWE
pfam02825 WWE domain; The WWE domain is named after three of its conserved residues and is predicted to ...
802-865
1.26e-25
WWE domain; The WWE domain is named after three of its conserved residues and is predicted to mediate specific protein- protein interactions in ubiquitin and ADP ribose conjugation systems.
Pssm-ID: 460715 [Multi-domain]
Cd Length: 66
Bit Score: 101.60
E-value: 1.26e-25
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 528508457 802 I W Q W R DD R G L WHPY NRID S RI IE T A H Q N G EDEIS LS -- T L G RV YTIDF N SM Q Q I N E DTGT A R AIQ R 865
Cdd:pfam02825 1 V W E W E DD N G G WHPY DPEV S SL IE E A Y Q K G KPSVD LS it T A G FP YTIDF K SM T Q T N K DTGT T R PVR R 66
WWE
smart00678 Domain in Deltex and TRIP12 homologues. Possibly involved in regulation of ubiquitin-mediated ...
802-869
1.02e-20
Domain in Deltex and TRIP12 homologues. Possibly involved in regulation of ubiquitin-mediated proteolysis;
Pssm-ID: 128922 [Multi-domain]
Cd Length: 73
Bit Score: 87.78
E-value: 1.02e-20
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 528508457 802 I W QWRDDR G L W H PY NRID S RI IE T A HQN G EDEIS LS TL G RV YTIDFN S M Q Q I N ED TGT A R AIQ R KPNP 869
Cdd:smart00678 2 V W EYEGRN G K W W PY DPRV S ED IE E A YAA G KKLCE LS IC G FP YTIDFN A M T Q Y N QA TGT T R KVR R VTYS 69
Metaviral_G
pfam09595 Metaviral_G glycoprotein; This is a viral attachment glycoprotein from region G of metaviruses. ...
48-170
2.49e-06
Metaviral_G glycoprotein; This is a viral attachment glycoprotein from region G of metaviruses. It is high in serine and threonine suggesting it is highly glycosylated.
Pssm-ID: 462833 [Multi-domain]
Cd Length: 183
Bit Score: 49.95
E-value: 2.49e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528508457 48 P D LEAAGTSGQ Q GRR E GSS - TR A L K RS - S V SE PNIT fs PS P AKRPKVVSSHFSDSSA sgp S A PAIS P EVT EP RKA P ASVS 125
Cdd:pfam09595 51 I D ININKQHPE Q EHH E NPP l NE A A K EA p S E SE DAPD -- ID P NNQHPSQDRSEAPPLE --- P A AKTK P SEH EP ANP P DASN 125
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 528508457 126 TK S KKRRLA A EPAP AR ALS K K S S - SYPG PS G A S S TP S QK R KKAD A T 170
Cdd:pfam09595 126 RL S PPDAST A AIRE AR TFR K P S T g KRNN PS S A Q S DQ S PP R ANHE A I 171
PHA03307
PHA03307 transcriptional regulator ICP4; Provisional
59-440
2.56e-04
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain]
Cd Length: 1352
Bit Score: 46.32
E-value: 2.56e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528508457 59 QGR REGS S T RA l KR SS VSE P NI T FS P - SP AKR P - KVV S SHFSDSSAS GP SAP A IS P EVTEPRK A P AS VSTK S kkrrlaae 136
Cdd:PHA03307 99 SPA REGS P T PP - GP SS PDP P PP T PP P a SP PPS P a PDL S EMLRPVGSP GP PPA A SP P AAGASPA A V AS DAAS S -------- 169
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528508457 137 PAP A RA LS KKSSSYPG PS GASST P SQKRKK A D A TLLSSSS SS SLPS S S S AAG P L P P RS E A SR A akptklasksaasakag 216
Cdd:PHA03307 170 RQA A LP LS SPEETARA PS SPPAE P PPSTPP A A A SPRPPRR SS PISA S A S SPA P A P G RS A A DD A ----------------- 232
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528508457 217 c STVTDS SSSS A SS SSSSS ssssaat GT N S C A --- P QGAR L KQGKDQSKARRSR S ASSPSPRR SS RDK E Q S KAAGS S KFD 293
Cdd:PHA03307 233 - GASSSD SSSS E SS GCGWG ------- PE N E C P lpr P APIT L PTRIWEASGWNGP S SRPGPASS SS SPR E R S PSPSP S SPG 304
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528508457 294 WASRFN S KVNLPKPKL S LPG S AKAET SS KPGPS G LQAKLASLRKSTKKR S ES PP AEL PS CR R STRQKTTGSCASTSRR G S 373
Cdd:PHA03307 305 SGPAPS S PRASSSSSS S RES S SSSTS SS SESSR G AAVSPGPSPSRSPSP S RP PP PAD PS SP R KRPRPSRAPSSPAASA G R 384
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 528508457 374 GLGK R GA A EARRQEKMA D SDNNQDG ans SAA R TEETPQ GA SASSSV A GAVGM T T SGE S -- E S DDSEM GR 440
Cdd:PHA03307 385 PTRR R AR A AVAGRARRR D ATGRFPA --- GRP R PSPLDA GA ASGAFY A RYPLL T P SGE P wp G S PPPPP GR 450
SRP1
COG5064 Karyopherin (importin) alpha [Intracellular trafficking and secretion];
480-671
1.88e-03
Karyopherin (importin) alpha [Intracellular trafficking and secretion];
Pssm-ID: 227396 [Multi-domain]
Cd Length: 526
Bit Score: 43.34
E-value: 1.88e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528508457 480 QL L Q G L QAT g D ES QQLQA AIEMCQ LL VMGNEETLGGFPVKS VVP ALITLLQ m E HNF D IMN - H A SR ALT YMMEALPRSSA V 558
Cdd:COG5064 75 QL T Q Q L FSD - D IE QQLQA VYKFRK LL SKETSPPIQPVIDAG VVP RFVEFMD - E IQR D MLQ f E A AW ALT NIASGTTQQTK V 152
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528508457 559 VVD -- A I P V F LEK L QVIQ f I DV A EQA LT AL EML --- S RRHSKAI LQ A G G L ADC L LY L EFFS I NAQ -- RNA LAIAA N C C QS 631
Cdd:COG5064 153 VVD ag A V P L F IQL L SSTE - D DV R EQA VW AL GNI agd S EGCRDYV LQ C G A L EPL L GL L LSSA I HIS ml RNA TWTLS N L C RG 231
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 528508457 632 IT P D - EFHFVADS LP L L TQRLTHQ D KKSVEST C LCFAR L V D 671
Cdd:COG5064 232 KN P P p DWSNISQA LP I L AKLIYSR D PEVLVDA C WAISY L S D 272
PRK07003
PRK07003 DNA polymerase III subunit gamma/tau;
52-203
3.74e-03
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain]
Cd Length: 830
Bit Score: 42.53
E-value: 3.74e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528508457 52 A AG TSGQQ G R R EGSSTR A lk RSSVSEPNI T FSPSP A KR PK VVSSHFSDSSASG P S APA --- ISPEVTEPRKAP A S V ST K S 128
Cdd:PRK07003 376 V AG AVPAP G A R AAAAVG A -- SAVPAVTAV T GAAGA A LA PK AAAAAAATRAEAP P A APA ppa TADRGDDAADGD A P V PA K A 453
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528508457 129 KK R RL A AEPAPA R ALSKKSS S YPGPSG AS ST P SQKRKK ---- A D A TLLSSSSSSSLPSSSS AA G ---- P LPPRSE A SR A A 200
Cdd:PRK07003 454 NA R AS A DSRCDE R DAQPPAD S GSASAP AS DA P PDAAFE papr A A A PSAATPAAVPDARAPA AA S reda P AAAAPP A PE A R 533
...
gi 528508457 201 K PT 203
Cdd:PRK07003 534 P PT 536
Name
Accession
Description
Interval
E-value
HECTc
cd00078 HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It ...
1651-2052
1.77e-123
HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ubiquitin molecules to the end of growing ubiquitin chains.
Pssm-ID: 238033 [Multi-domain]
Cd Length: 352
Bit Score: 393.47
E-value: 1.77e-123
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528508457 1651 K R T IN RD EL L KQ A ESVMQDLG SS -- RAM LE IQYEN E V G TG - L G P T Q EF YA LVS Q EL QRADL GL W R GEE vtlsnpkvgsqe 1727
Cdd:cd00078 2 K I T VR RD RI L ED A LRQLSKVS SS dl KKV LE VEFVG E E G ID a G G V T R EF FT LVS K EL FNPSY GL F R YTP ------------ 69
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528508457 1728 gtkym FS S RG L FAV P FGRTTK pahia KIKMK FRFLG K L MA KA IMDF RLLDLP LGLP FYK WM L RH es SI S SH DL VNI DP GV 1807
Cdd:cd00078 70 ----- DD S GL L YPN P SSFADE ----- DHLKL FRFLG R L LG KA LYEG RLLDLP FSRA FYK KL L GK -- PL S LE DL EEL DP EL 137
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528508457 1808 A KS IQH L ediirqkkrieqdrshtretlqqales L NMN G c SVE DL G L D FT ------ LP G FPNI ELK K GG K D V PVT IH N L E 1881
Cdd:cd00078 138 Y KS LKE L --------------------------- L DND G - DED DL E L T FT ieldss FG G AVTV ELK P GG R D I PVT NE N K E 189
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528508457 1882 D Y LR L V V YWT LN E G VLR Q F E S FR E GF ES V F P LHH L QY F Y PEEL DQ L L CG sk SE SW D VKT L MECCRPDH GY TH DS RAVRFL 1961
Cdd:cd00078 190 E Y VD L Y V DYR LN K G IEE Q V E A FR D GF SE V I P EEL L SL F T PEEL EL L I CG -- SE DI D LED L KKNTEYKG GY SS DS PTIQWF 267
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528508457 1962 F EVL S SF DA E QQRL FLQFVTGS P RLPVGGF RS LNP PL TI V R K tfest EN PDD F LP SVM TC V N Y LKLP D YSS I EI M REKLL 2041
Cdd:cd00078 268 W EVL E SF TN E ERKK FLQFVTGS S RLPVGGF AD LNP KF TI R R V ----- GS PDD R LP TAH TC F N L LKLP P YSS K EI L REKLL 342
410
....*....|.
gi 528508457 2042 I A AR EG q QS F H 2052
Cdd:cd00078 343 Y A IN EG - AG F G 352
HECTc
smart00119 Domain Homologous to E6-AP Carboxyl Terminus with; E3 ubiquitin-protein ligases. Can bind to ...
1669-2048
5.02e-119
Domain Homologous to E6-AP Carboxyl Terminus with; E3 ubiquitin-protein ligases. Can bind to E2 enzymes.
Pssm-ID: 214523
Cd Length: 328
Bit Score: 379.66
E-value: 5.02e-119
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528508457 1669 DL GSSR am LEI QY E N E V G - T G L G P T Q EF YA L V S Q EL QRA D L GL W R geevtlsnpkvgsqegtk Y MFSSRG L FAV P FGRTT 1747
Cdd:smart00119 1 DL KKRV -- LEI EF E G E E G l D G G G V T R EF FF L L S K EL FNP D Y GL F R ------------------ Y SPNDYL L YPN P RSGFA 60
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528508457 1748 KPA H I akik MK FRF L G KLMA KA IM D F RLLDL PLGL PFYK WM L RH es SISS HDL VNI DP GVA KS IQH L ediirqkk RIEQ D 1827
Cdd:smart00119 61 NEE H L ---- SY FRF I G RVLG KA LY D N RLLDL FFAR PFYK KL L GK -- PVTL HDL ESL DP ELY KS LKW L -------- LLNN D 126
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528508457 1828 R S htretlqqal E S L NMN gcsv EDLG L DFTLPGFPNI ELK K GG KDV PVT IH N LED Y LR LV VYWT LN E G VLR Q F E S FREGF 1907
Cdd:smart00119 127 T S ---------- E E L DLT ---- FSIV L TSEFGQVKVV ELK P GG SNI PVT EE N KKE Y VH LV IEYR LN K G IEK Q L E A FREGF 192
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528508457 1908 ES V F P LHH L QY F Y PEEL DQ L L CGS ks ESW DV KT L MECCRPDH GY THD S RAVRFLF EV LS SF DA E QQ R LF LQFVTGS P RLP 1987
Cdd:smart00119 193 SE V I P ENL L KL F D PEEL EL L I CGS -- PEI DV DD L KSNTEYKG GY SAN S QTIKWFW EV VE SF TN E ER R KL LQFVTGS S RLP 270
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 528508457 1988 VGGF RS L N P PL TI VRKTFE stenp D DF LP SVM TC V N Y LKLP D YSS I EI M REKLL I A AR EG Q 2048
Cdd:smart00119 271 VGGF AA L S P KF TI RKAGSD ----- D ER LP TAH TC F N R LKLP P YSS K EI L REKLL L A IN EG K 326
HECT
pfam00632 HECT-domain (ubiquitin-transferase); The name HECT comes from Homologous to the E6-AP Carboxyl ...
1698-2054
8.77e-103
HECT-domain (ubiquitin-transferase); The name HECT comes from Homologous to the E6-AP Carboxyl Terminus.
Pssm-ID: 459880
Cd Length: 304
Bit Score: 332.27
E-value: 8.77e-103
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528508457 1698 L V S Q EL QRADL GL WR geevtlsnpk VGSQEGTK Y M F S srglfav P FGRTTKPAHIAK ikm K F R FLGKL MA KAI MDFR LLD 1777
Cdd:pfam00632 2 L L S K EL FDPNY GL FE ---------- YETEDDRT Y W F N ------- P SSSESPDLELLD --- Y F K FLGKL LG KAI YNGI LLD 61
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528508457 1778 LP LGLP FYK WM L R he SSISSH DL VN IDP GVA KS IQH L ediirqkkrieqdrshtretlqqales LNM NGCSV EDLGL D FT 1857
Cdd:pfam00632 62 LP FPPF FYK KL L G -- EPLTLE DL ES IDP ELY KS LKS L --------------------------- LNM DNDDD EDLGL T FT 112
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528508457 1858 L P G F --- PN IEL KKG G KDV PVT IH N L E D Y L RL V V YWT LN EGVLR Q F E S FR E GF E SV F P LHH L QY F Y PEEL DQ L L CG sk S E 1934
Cdd:pfam00632 113 I P V F ges KT IEL IPN G RNI PVT NE N K E E Y I RL Y V DYR LN KSIEP Q L E A FR K GF Y SV I P KEA L SL F T PEEL EL L I CG -- S P 190
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528508457 1935 SW DV KT L MECCRP D H GYT HD S RAVRFLF E V L SS F DA EQ Q RLFL Q FVTGS P RLPVGGF R SL n P PL TIVRK TF este NP DD F 2014
Cdd:pfam00632 191 EI DV ED L KKNTEY D G GYT KN S PTIQWFW E I L EE F SP EQ R RLFL K FVTGS S RLPVGGF K SL - P KF TIVRK GG ---- DD DD R 265
330 340 350 360
....*....|....*....|....*....|....*....|
gi 528508457 2015 LP SVM TC V N Y LKLPDYSS I EI MR EKLLIA AR EG q QS F H LS 2054
Cdd:pfam00632 266 LP TAH TC F N R LKLPDYSS K EI LK EKLLIA IE EG - EG F G LS 304
HUL4
COG5021 Ubiquitin-protein ligase [Posttranslational modification, protein turnover, chaperones];
1564-2053
6.65e-81
Ubiquitin-protein ligase [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 227354 [Multi-domain]
Cd Length: 872
Bit Score: 287.43
E-value: 6.65e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528508457 1564 FINSKLTAKAN R QLQDPLVIMTGNIPTWLTEL G ktc P FFFPFD TR QMLF Y VTA F D r DRAMQR L LDTNPEINQSD S QDSRV 1643
Cdd:COG5021 413 TYEDLRREQLG R ESDESFYVASNVQQQRASRE G --- P LLSGWK TR LNNL Y RFY F V - EHRKKT L TKNDSRLGSFI S LNKLD 488
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528508457 1644 AP R LDRK KR TINRDE L LKQ A ESVM -- QDLGSS R AM ---- LEIQYEN E V G TG L GP T Q E FYALVSQEL qra D L G LWRG E EVT 1717
Cdd:COG5021 489 IR R IKED KR RKLFYS L KQK A KIFD py LHIKVR R DR vfed SYREIMD E S G DD L KK T L E IEFVGEEGI --- D A G GLTR E WLF 565
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528508457 1718 L SNPKVGSQEGTKYMFSSRG L FAV P FGRT -- TK P A H IAK ikmk F R FLG KLMA KAI M D F R L LD LPLGLP FYK WM L RH es SI 1795
Cdd:COG5021 566 L LSKEMFNPDYGLFEYITED L YTL P INPL ss IN P E H LSY ---- F K FLG RVIG KAI Y D S R I LD VQFSKA FYK KL L GK -- PV 639
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528508457 1796 S SH DL VNI DP GVAK S IQH L EDIIRQKKRIE qdrshtretlqqales L NM ngc S VED LGLDFTLP gfpn I EL KKG G KDVP V 1875
Cdd:COG5021 640 S LV DL ESL DP ELYR S LVW L LNNDIDETILD ---------------- L TF --- T VED DSFGESRT ---- V EL IPN G RNIS V 696
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528508457 1876 T IH N LED Y LRL VV YWT LN EG V LR QF ES F RE GF ESVF P LHH LQ Y F YPE EL DQ L LC G S k S E SW D VKTLMECCR p D HGYT H DS 1955
Cdd:COG5021 697 T NE N KKE Y VKK VV DYK LN KR V EK QF SA F KS GF SEII P PDL LQ I F DES EL EL L IG G I - P E DI D IDDWKSNTA - Y HGYT E DS 774
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528508457 1956 RAVRFLF E VL S S FD A E QQRLF LQFVTG SP R L P VG GF RS L NPPLTIVRK T F E STENP DD F LPS VM TC V N Y LKLP D YSS I E I 2035
Cdd:COG5021 775 PIIVWFW E II S E FD F E ERAKL LQFVTG TS R I P IN GF KD L QGSDGVRKF T I E KGGTD DD R LPS AH TC F N R LKLP E YSS K E K 854
490
....*....|....*...
gi 528508457 2036 M R E KLL I A AR EG QQSFH L 2053
Cdd:COG5021 855 L R S KLL T A IN EG AGFGL L 872
WWE
pfam02825 WWE domain; The WWE domain is named after three of its conserved residues and is predicted to ...
802-865
1.26e-25
WWE domain; The WWE domain is named after three of its conserved residues and is predicted to mediate specific protein- protein interactions in ubiquitin and ADP ribose conjugation systems.
Pssm-ID: 460715 [Multi-domain]
Cd Length: 66
Bit Score: 101.60
E-value: 1.26e-25
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 528508457 802 I W Q W R DD R G L WHPY NRID S RI IE T A H Q N G EDEIS LS -- T L G RV YTIDF N SM Q Q I N E DTGT A R AIQ R 865
Cdd:pfam02825 1 V W E W E DD N G G WHPY DPEV S SL IE E A Y Q K G KPSVD LS it T A G FP YTIDF K SM T Q T N K DTGT T R PVR R 66
WWE
smart00678 Domain in Deltex and TRIP12 homologues. Possibly involved in regulation of ubiquitin-mediated ...
802-869
1.02e-20
Domain in Deltex and TRIP12 homologues. Possibly involved in regulation of ubiquitin-mediated proteolysis;
Pssm-ID: 128922 [Multi-domain]
Cd Length: 73
Bit Score: 87.78
E-value: 1.02e-20
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 528508457 802 I W QWRDDR G L W H PY NRID S RI IE T A HQN G EDEIS LS TL G RV YTIDFN S M Q Q I N ED TGT A R AIQ R KPNP 869
Cdd:smart00678 2 V W EYEGRN G K W W PY DPRV S ED IE E A YAA G KKLCE LS IC G FP YTIDFN A M T Q Y N QA TGT T R KVR R VTYS 69
Metaviral_G
pfam09595 Metaviral_G glycoprotein; This is a viral attachment glycoprotein from region G of metaviruses. ...
48-170
2.49e-06
Metaviral_G glycoprotein; This is a viral attachment glycoprotein from region G of metaviruses. It is high in serine and threonine suggesting it is highly glycosylated.
Pssm-ID: 462833 [Multi-domain]
Cd Length: 183
Bit Score: 49.95
E-value: 2.49e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528508457 48 P D LEAAGTSGQ Q GRR E GSS - TR A L K RS - S V SE PNIT fs PS P AKRPKVVSSHFSDSSA sgp S A PAIS P EVT EP RKA P ASVS 125
Cdd:pfam09595 51 I D ININKQHPE Q EHH E NPP l NE A A K EA p S E SE DAPD -- ID P NNQHPSQDRSEAPPLE --- P A AKTK P SEH EP ANP P DASN 125
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 528508457 126 TK S KKRRLA A EPAP AR ALS K K S S - SYPG PS G A S S TP S QK R KKAD A T 170
Cdd:pfam09595 126 RL S PPDAST A AIRE AR TFR K P S T g KRNN PS S A Q S DQ S PP R ANHE A I 171
PHA03307
PHA03307 transcriptional regulator ICP4; Provisional
59-440
2.56e-04
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain]
Cd Length: 1352
Bit Score: 46.32
E-value: 2.56e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528508457 59 QGR REGS S T RA l KR SS VSE P NI T FS P - SP AKR P - KVV S SHFSDSSAS GP SAP A IS P EVTEPRK A P AS VSTK S kkrrlaae 136
Cdd:PHA03307 99 SPA REGS P T PP - GP SS PDP P PP T PP P a SP PPS P a PDL S EMLRPVGSP GP PPA A SP P AAGASPA A V AS DAAS S -------- 169
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528508457 137 PAP A RA LS KKSSSYPG PS GASST P SQKRKK A D A TLLSSSS SS SLPS S S S AAG P L P P RS E A SR A akptklasksaasakag 216
Cdd:PHA03307 170 RQA A LP LS SPEETARA PS SPPAE P PPSTPP A A A SPRPPRR SS PISA S A S SPA P A P G RS A A DD A ----------------- 232
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528508457 217 c STVTDS SSSS A SS SSSSS ssssaat GT N S C A --- P QGAR L KQGKDQSKARRSR S ASSPSPRR SS RDK E Q S KAAGS S KFD 293
Cdd:PHA03307 233 - GASSSD SSSS E SS GCGWG ------- PE N E C P lpr P APIT L PTRIWEASGWNGP S SRPGPASS SS SPR E R S PSPSP S SPG 304
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528508457 294 WASRFN S KVNLPKPKL S LPG S AKAET SS KPGPS G LQAKLASLRKSTKKR S ES PP AEL PS CR R STRQKTTGSCASTSRR G S 373
Cdd:PHA03307 305 SGPAPS S PRASSSSSS S RES S SSSTS SS SESSR G AAVSPGPSPSRSPSP S RP PP PAD PS SP R KRPRPSRAPSSPAASA G R 384
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 528508457 374 GLGK R GA A EARRQEKMA D SDNNQDG ans SAA R TEETPQ GA SASSSV A GAVGM T T SGE S -- E S DDSEM GR 440
Cdd:PHA03307 385 PTRR R AR A AVAGRARRR D ATGRFPA --- GRP R PSPLDA GA ASGAFY A RYPLL T P SGE P wp G S PPPPP GR 450
SRP1
COG5064 Karyopherin (importin) alpha [Intracellular trafficking and secretion];
480-671
1.88e-03
Karyopherin (importin) alpha [Intracellular trafficking and secretion];
Pssm-ID: 227396 [Multi-domain]
Cd Length: 526
Bit Score: 43.34
E-value: 1.88e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528508457 480 QL L Q G L QAT g D ES QQLQA AIEMCQ LL VMGNEETLGGFPVKS VVP ALITLLQ m E HNF D IMN - H A SR ALT YMMEALPRSSA V 558
Cdd:COG5064 75 QL T Q Q L FSD - D IE QQLQA VYKFRK LL SKETSPPIQPVIDAG VVP RFVEFMD - E IQR D MLQ f E A AW ALT NIASGTTQQTK V 152
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528508457 559 VVD -- A I P V F LEK L QVIQ f I DV A EQA LT AL EML --- S RRHSKAI LQ A G G L ADC L LY L EFFS I NAQ -- RNA LAIAA N C C QS 631
Cdd:COG5064 153 VVD ag A V P L F IQL L SSTE - D DV R EQA VW AL GNI agd S EGCRDYV LQ C G A L EPL L GL L LSSA I HIS ml RNA TWTLS N L C RG 231
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 528508457 632 IT P D - EFHFVADS LP L L TQRLTHQ D KKSVEST C LCFAR L V D 671
Cdd:COG5064 232 KN P P p DWSNISQA LP I L AKLIYSR D PEVLVDA C WAISY L S D 272
PRK07003
PRK07003 DNA polymerase III subunit gamma/tau;
52-203
3.74e-03
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain]
Cd Length: 830
Bit Score: 42.53
E-value: 3.74e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528508457 52 A AG TSGQQ G R R EGSSTR A lk RSSVSEPNI T FSPSP A KR PK VVSSHFSDSSASG P S APA --- ISPEVTEPRKAP A S V ST K S 128
Cdd:PRK07003 376 V AG AVPAP G A R AAAAVG A -- SAVPAVTAV T GAAGA A LA PK AAAAAAATRAEAP P A APA ppa TADRGDDAADGD A P V PA K A 453
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528508457 129 KK R RL A AEPAPA R ALSKKSS S YPGPSG AS ST P SQKRKK ---- A D A TLLSSSSSSSLPSSSS AA G ---- P LPPRSE A SR A A 200
Cdd:PRK07003 454 NA R AS A DSRCDE R DAQPPAD S GSASAP AS DA P PDAAFE papr A A A PSAATPAAVPDARAPA AA S reda P AAAAPP A PE A R 533
...
gi 528508457 201 K PT 203
Cdd:PRK07003 534 P PT 536
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
