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Conserved domains on  [gi|528520540|ref|XP_005162972|]
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solute carrier family 12 member 7 isoform X6 [Danio rerio]

Protein Classification

solute carrier family 12 protein( domain architecture ID 11489985)

solute carrier family 12 protein similar to Arabidopsis thaliana cation-chloride cotransporter 1, which mediates both potassium-chloride and sodium-chloride cotransports and is involved in plant development and Cl(-) homeostasis

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
2a30 TIGR00930
K-Cl cotransporter; [Transport and binding proteins, Other]
14-1094 0e+00

K-Cl cotransporter; [Transport and binding proteins, Other]


:

Pssm-ID: 273347 [Multi-domain]  Cd Length: 953  Bit Score: 1231.89  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540    14 NPRESSPFINNTDDDKGNLYDGKNMALFEEEMDSNPMVSSLLNKLANYTNLTQGVREHEEADEDEGAKKQTVK-SPQMGT 92
Cdd:TIGR00930    1 NTVDAVPRIEHYRNSEGQGGPKRNRPSLEELHDLLDKVVSLLGPLADYTNNGQGMKEHEEAEDAEGTKEKPPAgAVKFGW 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540    93 FIGVYLPCLQNILGVILFLRMTWIVGTAGILEAFIIVSMCCSCTMLTAISMSAIATNGVVPAGGSYYMISRSLGPEFGGA 172
Cdd:TIGR00930   81 VMGVLVPCLLNIWGVILFLRLSWIVGQAGIGLSLLIILLCCCVTTITGLSMSAIATNGVVKGGGAYYLISRSLGPEFGGS 160
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540   173 VGLCFYLGTTFAGAMYILGTIEILLTyivpsaaIFKaEDKADEAEALLNNMRVYGTCCLTLMALVVFVGVKYVNKLALVF 252
Cdd:TIGR00930  161 IGLIFAFANAVAVAMYVVGFAETVLD-------LLR-ENGSKIMVDPINDIRIYGTVTVVVLLGISFAGMEWENKAQVLF 232
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540   253 LACVVLSILAIYAGVIKTIFEPPVFPVCVLGNRTLQNHdfdkcmkteiidnvtvttklwslfcsgpelnascneyftlns 332
Cdd:TIGR00930  233 LVIVLLSILNIFVGTIIPAFDKPAKGFFGLGNEIFSEN------------------------------------------ 270
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540   333 vtEIQGIPGLTSGvisenmwgkygpagmlvekdipsvsasdssqdkympyvvnditafFTLLVGIYFPSVTGIMAGSNRS 412
Cdd:TIGR00930  271 --FIPGIPGPEGG---------------------------------------------FFSLFGIFFPSVTGILAGANIS 303
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540   413 GDLRDAQRSIPIGTILAIATTTIIYLSCVVLFGACIEGVVLRDKFGDSVK---------------------GNLVIGTLS 471
Cdd:TIGR00930  304 GDLKDPQKAIPKGTLLAILTTTVVYLGSVVLFGACVVRDATGDKNDTLVTnctsaacfsecahntcsyglmNNLQVMSLV 383
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540   472 WPSPWVIVIGSFFSCCGAGLQSLTGAPRLLQAIARDGIVPFLEVFGHGKA-NGEPTWALLLTALICESGILIASLDAVAP 550
Cdd:TIGR00930  384 SPFPPLITAGIFSATLSSALASLVSAPRLFQALCKDNIYPFLQFFGKGYGkNGEPLRAYLLTAFIAEGFILIAELNTIAP 463
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540   551 ILSMFFLMCYLFVNLACALQTLLRTPNWRPRFKYYHWALSFLGMSLCLALMFISSWYYALVAMLIAGCIYKYIEYRGAEK 630
Cdd:TIGR00930  464 IISNFFLASYALINFSCFHASLLRSPGWRPRFKYYHWWLSLLGASLCCAIMFLISWWAALVAMVIALFLYKYVTYKKPDV 543
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540   631 EWGDGIRGLSLNAARYALIRLEEAPPHTKNWRPQMLVLLNLDselcVKHPRLLSFTTQLKAGKGLTIVGSVLEGTYLSRE 710
Cdd:TIGR00930  544 NWGSSTQALSYSLALYSLLRLEEVEDHVKNWRPQCLVLTGPP----VCRPALLDFASQFTKGKGLMICGSVIQGPRLECV 619
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540   711 NQAKRAEQNIKSAMAAEKTKGFCHVVVSSNLRDGISHLVQSAGLGGMKHNSVLMAWPSNWRQsSDPHTWRSFIETVRETT 790
Cdd:TIGR00930  620 KEAQAAEAKIQTWLEKNKVKAFYAVVVADDLREGVRHLIQASGLGRMKPNTLVMGYKKDWRQ-AEPRAWETYIGIIHDAF 698
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540   791 AAHLALLVAKNVDSFP---------------------------------------HQERLTEGTIDVWWIVHDGGMLMLL 831
Cdd:TIGR00930  699 DAHLAVVVVRNSEGLPisvlqvqeelendcsedsielndgkistqpdmhleastqFQKKQGKGTIDVWWLVDDGGLTLLL 778
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540   832 PFLLRQHKVWKKCKMRIFTVAQMDDNSIQMKKDLQMFLYHLRLNAEVEVVEMhdsDISAftYEKTLVMEQRSQMLKQMQL 911
Cdd:TIGR00930  779 PYLLTTKKVWKKCKIRIFVGAQKDDRSEQEKKDMATLLYKFRIDAEVIVVLM---DINA--KPQTESMEAFEEMIRPFRL 853
                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540   912 SRTEREREiqsitdesrssirrknqseahssslqnqntaheqqdeaqlihdrntashtamndkadaTPERvHMTWTKEKL 991
Cdd:TIGR00930  854 HKTEKDRE----------------------------------------------------------AKDP-KMTWTKPWK 874
                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540   992 FSERSrrteanasmavrdlfnmkpeweslNQSNVRCMHTAVKLNEVIVNKSQGAHLVLLNMPGPPKNRGGDENYMEFMEV 1071
Cdd:TIGR00930  875 ITDAE------------------------LQSNVRKSYRQVRLNELLLEYSRDAALVVLSLPVPRKGSIPDELYMAWLEV 930
                         1130      1140
                   ....*....|....*....|...
gi 528520540  1072 MMEGLNRVLLVRGGGREVITIYS 1094
Cdd:TIGR00930  931 LSEDLPPVLLVRGNHRNVLTFYS 953
 
Name Accession Description Interval E-value
2a30 TIGR00930
K-Cl cotransporter; [Transport and binding proteins, Other]
14-1094 0e+00

K-Cl cotransporter; [Transport and binding proteins, Other]


Pssm-ID: 273347 [Multi-domain]  Cd Length: 953  Bit Score: 1231.89  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540    14 NPRESSPFINNTDDDKGNLYDGKNMALFEEEMDSNPMVSSLLNKLANYTNLTQGVREHEEADEDEGAKKQTVK-SPQMGT 92
Cdd:TIGR00930    1 NTVDAVPRIEHYRNSEGQGGPKRNRPSLEELHDLLDKVVSLLGPLADYTNNGQGMKEHEEAEDAEGTKEKPPAgAVKFGW 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540    93 FIGVYLPCLQNILGVILFLRMTWIVGTAGILEAFIIVSMCCSCTMLTAISMSAIATNGVVPAGGSYYMISRSLGPEFGGA 172
Cdd:TIGR00930   81 VMGVLVPCLLNIWGVILFLRLSWIVGQAGIGLSLLIILLCCCVTTITGLSMSAIATNGVVKGGGAYYLISRSLGPEFGGS 160
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540   173 VGLCFYLGTTFAGAMYILGTIEILLTyivpsaaIFKaEDKADEAEALLNNMRVYGTCCLTLMALVVFVGVKYVNKLALVF 252
Cdd:TIGR00930  161 IGLIFAFANAVAVAMYVVGFAETVLD-------LLR-ENGSKIMVDPINDIRIYGTVTVVVLLGISFAGMEWENKAQVLF 232
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540   253 LACVVLSILAIYAGVIKTIFEPPVFPVCVLGNRTLQNHdfdkcmkteiidnvtvttklwslfcsgpelnascneyftlns 332
Cdd:TIGR00930  233 LVIVLLSILNIFVGTIIPAFDKPAKGFFGLGNEIFSEN------------------------------------------ 270
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540   333 vtEIQGIPGLTSGvisenmwgkygpagmlvekdipsvsasdssqdkympyvvnditafFTLLVGIYFPSVTGIMAGSNRS 412
Cdd:TIGR00930  271 --FIPGIPGPEGG---------------------------------------------FFSLFGIFFPSVTGILAGANIS 303
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540   413 GDLRDAQRSIPIGTILAIATTTIIYLSCVVLFGACIEGVVLRDKFGDSVK---------------------GNLVIGTLS 471
Cdd:TIGR00930  304 GDLKDPQKAIPKGTLLAILTTTVVYLGSVVLFGACVVRDATGDKNDTLVTnctsaacfsecahntcsyglmNNLQVMSLV 383
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540   472 WPSPWVIVIGSFFSCCGAGLQSLTGAPRLLQAIARDGIVPFLEVFGHGKA-NGEPTWALLLTALICESGILIASLDAVAP 550
Cdd:TIGR00930  384 SPFPPLITAGIFSATLSSALASLVSAPRLFQALCKDNIYPFLQFFGKGYGkNGEPLRAYLLTAFIAEGFILIAELNTIAP 463
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540   551 ILSMFFLMCYLFVNLACALQTLLRTPNWRPRFKYYHWALSFLGMSLCLALMFISSWYYALVAMLIAGCIYKYIEYRGAEK 630
Cdd:TIGR00930  464 IISNFFLASYALINFSCFHASLLRSPGWRPRFKYYHWWLSLLGASLCCAIMFLISWWAALVAMVIALFLYKYVTYKKPDV 543
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540   631 EWGDGIRGLSLNAARYALIRLEEAPPHTKNWRPQMLVLLNLDselcVKHPRLLSFTTQLKAGKGLTIVGSVLEGTYLSRE 710
Cdd:TIGR00930  544 NWGSSTQALSYSLALYSLLRLEEVEDHVKNWRPQCLVLTGPP----VCRPALLDFASQFTKGKGLMICGSVIQGPRLECV 619
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540   711 NQAKRAEQNIKSAMAAEKTKGFCHVVVSSNLRDGISHLVQSAGLGGMKHNSVLMAWPSNWRQsSDPHTWRSFIETVRETT 790
Cdd:TIGR00930  620 KEAQAAEAKIQTWLEKNKVKAFYAVVVADDLREGVRHLIQASGLGRMKPNTLVMGYKKDWRQ-AEPRAWETYIGIIHDAF 698
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540   791 AAHLALLVAKNVDSFP---------------------------------------HQERLTEGTIDVWWIVHDGGMLMLL 831
Cdd:TIGR00930  699 DAHLAVVVVRNSEGLPisvlqvqeelendcsedsielndgkistqpdmhleastqFQKKQGKGTIDVWWLVDDGGLTLLL 778
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540   832 PFLLRQHKVWKKCKMRIFTVAQMDDNSIQMKKDLQMFLYHLRLNAEVEVVEMhdsDISAftYEKTLVMEQRSQMLKQMQL 911
Cdd:TIGR00930  779 PYLLTTKKVWKKCKIRIFVGAQKDDRSEQEKKDMATLLYKFRIDAEVIVVLM---DINA--KPQTESMEAFEEMIRPFRL 853
                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540   912 SRTEREREiqsitdesrssirrknqseahssslqnqntaheqqdeaqlihdrntashtamndkadaTPERvHMTWTKEKL 991
Cdd:TIGR00930  854 HKTEKDRE----------------------------------------------------------AKDP-KMTWTKPWK 874
                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540   992 FSERSrrteanasmavrdlfnmkpeweslNQSNVRCMHTAVKLNEVIVNKSQGAHLVLLNMPGPPKNRGGDENYMEFMEV 1071
Cdd:TIGR00930  875 ITDAE------------------------LQSNVRKSYRQVRLNELLLEYSRDAALVVLSLPVPRKGSIPDELYMAWLEV 930
                         1130      1140
                   ....*....|....*....|...
gi 528520540  1072 MMEGLNRVLLVRGGGREVITIYS 1094
Cdd:TIGR00930  931 LSEDLPPVLLVRGNHRNVLTFYS 953
AA_permease pfam00324
Amino acid permease;
95-666 8.44e-45

Amino acid permease;


Pssm-ID: 366028 [Multi-domain]  Cd Length: 467  Bit Score: 169.04  E-value: 8.44e-45
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540    95 GVYLPCLQNILGVILFLRMTWIVGTAGILEAFIIVSMCCSCTMLTAISMSAIATNGVVpAGGSYYMISRSLGPEFGGAVG 174
Cdd:pfam00324    1 HVQMIALGGVIGTGLFVGSGSVLGQAGPAGALLGYLISGVVIFLVMLSLGEISTNGPV-SGGFYTYASRFLGPSLGFATG 79
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540   175 LcFYLGTTFAGAMYILGTIEILLTYIVPSAAIFKAEdkadeaeallnnmrVYGTCCLTLMALVVFVGVKYVNKLALVFLA 254
Cdd:pfam00324   80 W-NYWLSWITVLALELTAASILIQFWELVPDIPYLW--------------VWGAVFLVLLTIINLVGVKWYGEAEFWFAL 144
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540   255 CVVLSILAIYAGVIKTIFeppvfpvcvlgnrtlqnhdfdkcmkteiidnvtvttklwslfcsgpelnascneyftlnsvt 334
Cdd:pfam00324  145 IKIIAIIGFIIVGIILLS-------------------------------------------------------------- 162
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540   335 eiqgIPGLTSGVISENMWGKYGPAgmlvekdipsvsasdssqdkympYVVNDI-TAFFTLLVgIYFPSVTGIMAGSNRSG 413
Cdd:pfam00324  163 ----GGNPNDGAIFRYLGDNGGKN-----------------------NFPPGFgKGFISVFV-IAFFAFTGIELVGIAAG 214
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540   414 DLRDAQRSIPIGTILAIATTTIIYLSCVVLFGACIEG---VVLRDKFGDSVKGNLVIGTLSWPS-PWVIVIGSFFSCCGA 489
Cdd:pfam00324  215 EVKNPEKSIPKAILQVIWRITIFYILSLLAIGLLVPWndpGLLNDSASAASPFVIFFKFLGISGlAPLINAVILTAALSA 294
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540   490 GLQSLTGAPRLLQAIARDGIVPFleVFGHGKANGEPTWALLLTALICESGILIASLdaVAPILSMFFLMCYLFVNLACAL 569
Cdd:pfam00324  295 ANSSLYSGSRMLYSLARDGLAPK--FLKKVDKRGVPLRAILVSMVISLLALLLASL--NPAIVFNFLLAISGLSGLIVWG 370
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540   570 QTLLRTPNWRPRFKYYHWALSFLGMSLCLALMFISSWYYALVAMLIAGCIYKYIEYRGAEKEWGDGIRGLSLNAARYALI 649
Cdd:pfam00324  371 LISLSHLRFRKAFKYQGRSIDELPFKAPLGPLGVILGLAAIIIILIIQFLYAFLPVPGGPKNWGAGSFAAAYLIVLLFLI 450
                          570
                   ....*....|....*..
gi 528520540   650 RLEEAPPHTKNWRPQML 666
Cdd:pfam00324  451 ILIGVKLHVKNWKPQLL 467
PotE COG0531
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
103-626 1.70e-33

Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];


Pssm-ID: 440297 [Multi-domain]  Cd Length: 438  Bit Score: 135.02  E-value: 1.70e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540  103 NILGVILFLRMTWIVGTAG--ILEAFIIVSMCCsctMLTAISMSAIATNgvVP-AGGSYYMISRSLGPEFGGAVGLCFYL 179
Cdd:COG0531    25 AIIGAGIFVLPGLAAGLAGpaAILAWLIAGLLA---LLVALSYAELASA--FPrAGGAYTYARRALGPLLGFLAGWALLL 99
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540  180 GTTFAGAMYILGTIEiLLTYIVPSAAIFkaedkadeaeallnnmrVYGTCCLTLMALVVFVGVKYVNKLALVFLACVVLS 259
Cdd:COG0531   100 SYVLAVAAVAVAFGG-YLSSLFPAGGSV-----------------LIALVLILLLTLLNLRGVKESAKVNNILTVLKLLV 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540  260 ILAIYAGVIktifeppvfpvcvlgnrtlqnhdfdkcmkteiidnVTVTTKLWSLFcsgpelnascneyftlnsvteiqgI 339
Cdd:COG0531   162 LLLFIVVGL-----------------------------------FAFDPANFTPF------------------------L 182
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540  340 PGLTSgvisenmwgkygpagmlvekdipsvsasdssqdkympyvvndITAFFTLLVGIyFPSVTGIMAGSNRSGDLRDAQ 419
Cdd:COG0531   183 PAGGG------------------------------------------LSGVLAALALA-FFAFTGFEAIANLAEEAKNPK 219
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540  420 RSIPIGTILAIATTTIIYLSCVVLFGacieGVVLRDKFGDSVKGNLVIGTLSWPSP--WVIVIGSFFSCCGAGLQSLTGA 497
Cdd:COG0531   220 RNIPRAIILSLLIVGVLYILVSLALT----GVVPYDELAASGAPLADAAEAVFGPWgaILIALGALLSLLGALNASILGA 295
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540  498 PRLLQAIARDGIVPflEVFGH-GKANGEPTWALLLTALICESGILI--ASLDAVAPILSMFFLMCYLFVNLAcALQTLLR 574
Cdd:COG0531   296 SRLLYAMARDGLLP--KVFAKvHPRFGTPVNAILLTGVIALLLLLLgaASFTALASLASVGVLLAYLLVALA-VIVLRRR 372
                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 528520540  575 TPNWRPRFKYYHWALSFLGMSLCLALMFIS---SWYYALVAMLIAGCIYKYIEYR 626
Cdd:COG0531   373 RPDLPRPFRVPLPLIPILGILLCLFLLYLLgpgALLIGLVLLAIGLLLYLLYRRR 427
 
Name Accession Description Interval E-value
2a30 TIGR00930
K-Cl cotransporter; [Transport and binding proteins, Other]
14-1094 0e+00

K-Cl cotransporter; [Transport and binding proteins, Other]


Pssm-ID: 273347 [Multi-domain]  Cd Length: 953  Bit Score: 1231.89  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540    14 NPRESSPFINNTDDDKGNLYDGKNMALFEEEMDSNPMVSSLLNKLANYTNLTQGVREHEEADEDEGAKKQTVK-SPQMGT 92
Cdd:TIGR00930    1 NTVDAVPRIEHYRNSEGQGGPKRNRPSLEELHDLLDKVVSLLGPLADYTNNGQGMKEHEEAEDAEGTKEKPPAgAVKFGW 80
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540    93 FIGVYLPCLQNILGVILFLRMTWIVGTAGILEAFIIVSMCCSCTMLTAISMSAIATNGVVPAGGSYYMISRSLGPEFGGA 172
Cdd:TIGR00930   81 VMGVLVPCLLNIWGVILFLRLSWIVGQAGIGLSLLIILLCCCVTTITGLSMSAIATNGVVKGGGAYYLISRSLGPEFGGS 160
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540   173 VGLCFYLGTTFAGAMYILGTIEILLTyivpsaaIFKaEDKADEAEALLNNMRVYGTCCLTLMALVVFVGVKYVNKLALVF 252
Cdd:TIGR00930  161 IGLIFAFANAVAVAMYVVGFAETVLD-------LLR-ENGSKIMVDPINDIRIYGTVTVVVLLGISFAGMEWENKAQVLF 232
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540   253 LACVVLSILAIYAGVIKTIFEPPVFPVCVLGNRTLQNHdfdkcmkteiidnvtvttklwslfcsgpelnascneyftlns 332
Cdd:TIGR00930  233 LVIVLLSILNIFVGTIIPAFDKPAKGFFGLGNEIFSEN------------------------------------------ 270
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540   333 vtEIQGIPGLTSGvisenmwgkygpagmlvekdipsvsasdssqdkympyvvnditafFTLLVGIYFPSVTGIMAGSNRS 412
Cdd:TIGR00930  271 --FIPGIPGPEGG---------------------------------------------FFSLFGIFFPSVTGILAGANIS 303
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540   413 GDLRDAQRSIPIGTILAIATTTIIYLSCVVLFGACIEGVVLRDKFGDSVK---------------------GNLVIGTLS 471
Cdd:TIGR00930  304 GDLKDPQKAIPKGTLLAILTTTVVYLGSVVLFGACVVRDATGDKNDTLVTnctsaacfsecahntcsyglmNNLQVMSLV 383
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540   472 WPSPWVIVIGSFFSCCGAGLQSLTGAPRLLQAIARDGIVPFLEVFGHGKA-NGEPTWALLLTALICESGILIASLDAVAP 550
Cdd:TIGR00930  384 SPFPPLITAGIFSATLSSALASLVSAPRLFQALCKDNIYPFLQFFGKGYGkNGEPLRAYLLTAFIAEGFILIAELNTIAP 463
                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540   551 ILSMFFLMCYLFVNLACALQTLLRTPNWRPRFKYYHWALSFLGMSLCLALMFISSWYYALVAMLIAGCIYKYIEYRGAEK 630
Cdd:TIGR00930  464 IISNFFLASYALINFSCFHASLLRSPGWRPRFKYYHWWLSLLGASLCCAIMFLISWWAALVAMVIALFLYKYVTYKKPDV 543
                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540   631 EWGDGIRGLSLNAARYALIRLEEAPPHTKNWRPQMLVLLNLDselcVKHPRLLSFTTQLKAGKGLTIVGSVLEGTYLSRE 710
Cdd:TIGR00930  544 NWGSSTQALSYSLALYSLLRLEEVEDHVKNWRPQCLVLTGPP----VCRPALLDFASQFTKGKGLMICGSVIQGPRLECV 619
                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540   711 NQAKRAEQNIKSAMAAEKTKGFCHVVVSSNLRDGISHLVQSAGLGGMKHNSVLMAWPSNWRQsSDPHTWRSFIETVRETT 790
Cdd:TIGR00930  620 KEAQAAEAKIQTWLEKNKVKAFYAVVVADDLREGVRHLIQASGLGRMKPNTLVMGYKKDWRQ-AEPRAWETYIGIIHDAF 698
                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540   791 AAHLALLVAKNVDSFP---------------------------------------HQERLTEGTIDVWWIVHDGGMLMLL 831
Cdd:TIGR00930  699 DAHLAVVVVRNSEGLPisvlqvqeelendcsedsielndgkistqpdmhleastqFQKKQGKGTIDVWWLVDDGGLTLLL 778
                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540   832 PFLLRQHKVWKKCKMRIFTVAQMDDNSIQMKKDLQMFLYHLRLNAEVEVVEMhdsDISAftYEKTLVMEQRSQMLKQMQL 911
Cdd:TIGR00930  779 PYLLTTKKVWKKCKIRIFVGAQKDDRSEQEKKDMATLLYKFRIDAEVIVVLM---DINA--KPQTESMEAFEEMIRPFRL 853
                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540   912 SRTEREREiqsitdesrssirrknqseahssslqnqntaheqqdeaqlihdrntashtamndkadaTPERvHMTWTKEKL 991
Cdd:TIGR00930  854 HKTEKDRE----------------------------------------------------------AKDP-KMTWTKPWK 874
                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540   992 FSERSrrteanasmavrdlfnmkpeweslNQSNVRCMHTAVKLNEVIVNKSQGAHLVLLNMPGPPKNRGGDENYMEFMEV 1071
Cdd:TIGR00930  875 ITDAE------------------------LQSNVRKSYRQVRLNELLLEYSRDAALVVLSLPVPRKGSIPDELYMAWLEV 930
                         1130      1140
                   ....*....|....*....|...
gi 528520540  1072 MMEGLNRVLLVRGGGREVITIYS 1094
Cdd:TIGR00930  931 LSEDLPPVLLVRGNHRNVLTFYS 953
AA_permease pfam00324
Amino acid permease;
95-666 8.44e-45

Amino acid permease;


Pssm-ID: 366028 [Multi-domain]  Cd Length: 467  Bit Score: 169.04  E-value: 8.44e-45
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540    95 GVYLPCLQNILGVILFLRMTWIVGTAGILEAFIIVSMCCSCTMLTAISMSAIATNGVVpAGGSYYMISRSLGPEFGGAVG 174
Cdd:pfam00324    1 HVQMIALGGVIGTGLFVGSGSVLGQAGPAGALLGYLISGVVIFLVMLSLGEISTNGPV-SGGFYTYASRFLGPSLGFATG 79
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540   175 LcFYLGTTFAGAMYILGTIEILLTYIVPSAAIFKAEdkadeaeallnnmrVYGTCCLTLMALVVFVGVKYVNKLALVFLA 254
Cdd:pfam00324   80 W-NYWLSWITVLALELTAASILIQFWELVPDIPYLW--------------VWGAVFLVLLTIINLVGVKWYGEAEFWFAL 144
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540   255 CVVLSILAIYAGVIKTIFeppvfpvcvlgnrtlqnhdfdkcmkteiidnvtvttklwslfcsgpelnascneyftlnsvt 334
Cdd:pfam00324  145 IKIIAIIGFIIVGIILLS-------------------------------------------------------------- 162
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540   335 eiqgIPGLTSGVISENMWGKYGPAgmlvekdipsvsasdssqdkympYVVNDI-TAFFTLLVgIYFPSVTGIMAGSNRSG 413
Cdd:pfam00324  163 ----GGNPNDGAIFRYLGDNGGKN-----------------------NFPPGFgKGFISVFV-IAFFAFTGIELVGIAAG 214
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540   414 DLRDAQRSIPIGTILAIATTTIIYLSCVVLFGACIEG---VVLRDKFGDSVKGNLVIGTLSWPS-PWVIVIGSFFSCCGA 489
Cdd:pfam00324  215 EVKNPEKSIPKAILQVIWRITIFYILSLLAIGLLVPWndpGLLNDSASAASPFVIFFKFLGISGlAPLINAVILTAALSA 294
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540   490 GLQSLTGAPRLLQAIARDGIVPFleVFGHGKANGEPTWALLLTALICESGILIASLdaVAPILSMFFLMCYLFVNLACAL 569
Cdd:pfam00324  295 ANSSLYSGSRMLYSLARDGLAPK--FLKKVDKRGVPLRAILVSMVISLLALLLASL--NPAIVFNFLLAISGLSGLIVWG 370
                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540   570 QTLLRTPNWRPRFKYYHWALSFLGMSLCLALMFISSWYYALVAMLIAGCIYKYIEYRGAEKEWGDGIRGLSLNAARYALI 649
Cdd:pfam00324  371 LISLSHLRFRKAFKYQGRSIDELPFKAPLGPLGVILGLAAIIIILIIQFLYAFLPVPGGPKNWGAGSFAAAYLIVLLFLI 450
                          570
                   ....*....|....*..
gi 528520540   650 RLEEAPPHTKNWRPQML 666
Cdd:pfam00324  451 ILIGVKLHVKNWKPQLL 467
PotE COG0531
Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];
103-626 1.70e-33

Serine transporter YbeC, amino acid:H+ symporter family [Amino acid transport and metabolism];


Pssm-ID: 440297 [Multi-domain]  Cd Length: 438  Bit Score: 135.02  E-value: 1.70e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540  103 NILGVILFLRMTWIVGTAG--ILEAFIIVSMCCsctMLTAISMSAIATNgvVP-AGGSYYMISRSLGPEFGGAVGLCFYL 179
Cdd:COG0531    25 AIIGAGIFVLPGLAAGLAGpaAILAWLIAGLLA---LLVALSYAELASA--FPrAGGAYTYARRALGPLLGFLAGWALLL 99
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540  180 GTTFAGAMYILGTIEiLLTYIVPSAAIFkaedkadeaeallnnmrVYGTCCLTLMALVVFVGVKYVNKLALVFLACVVLS 259
Cdd:COG0531   100 SYVLAVAAVAVAFGG-YLSSLFPAGGSV-----------------LIALVLILLLTLLNLRGVKESAKVNNILTVLKLLV 161
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540  260 ILAIYAGVIktifeppvfpvcvlgnrtlqnhdfdkcmkteiidnVTVTTKLWSLFcsgpelnascneyftlnsvteiqgI 339
Cdd:COG0531   162 LLLFIVVGL-----------------------------------FAFDPANFTPF------------------------L 182
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540  340 PGLTSgvisenmwgkygpagmlvekdipsvsasdssqdkympyvvndITAFFTLLVGIyFPSVTGIMAGSNRSGDLRDAQ 419
Cdd:COG0531   183 PAGGG------------------------------------------LSGVLAALALA-FFAFTGFEAIANLAEEAKNPK 219
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540  420 RSIPIGTILAIATTTIIYLSCVVLFGacieGVVLRDKFGDSVKGNLVIGTLSWPSP--WVIVIGSFFSCCGAGLQSLTGA 497
Cdd:COG0531   220 RNIPRAIILSLLIVGVLYILVSLALT----GVVPYDELAASGAPLADAAEAVFGPWgaILIALGALLSLLGALNASILGA 295
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540  498 PRLLQAIARDGIVPflEVFGH-GKANGEPTWALLLTALICESGILI--ASLDAVAPILSMFFLMCYLFVNLAcALQTLLR 574
Cdd:COG0531   296 SRLLYAMARDGLLP--KVFAKvHPRFGTPVNAILLTGVIALLLLLLgaASFTALASLASVGVLLAYLLVALA-VIVLRRR 372
                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 528520540  575 TPNWRPRFKYYHWALSFLGMSLCLALMFIS---SWYYALVAMLIAGCIYKYIEYR 626
Cdd:COG0531   373 RPDLPRPFRVPLPLIPILGILLCLFLLYLLgpgALLIGLVLLAIGLLLYLLYRRR 427
SLC12 pfam03522
Solute carrier family 12;
680-852 1.25e-18

Solute carrier family 12;


Pssm-ID: 460955  Cd Length: 414  Bit Score: 89.60  E-value: 1.25e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540   680 PRLLSFTTQLKAGKGLTIVGSVLEG--TYLSRENQAKRAeqniKSAMAAEKTKGFCHVVVSSNLRDGISHLVQSAGLGGM 757
Cdd:pfam03522    2 PALVDFAHLITKNVSLMICGHVVKGrlSQKLRSELQKKA----YRWLRKRKIKAFYALVDGDNLREGAQALLQASGLGKL 77
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540   758 KHNSVLMAWPSNWRQSS-------------------------------------DPHTWRSFIETVRETTAAHLALLVAK 800
Cdd:pfam03522   78 KPNILLMGYKSDWRTCDkeeleeyfnvihdafdlqyavailrlpegldvshllqDQDTEELGLGDETNSSYAEQSSEEQS 157
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540   801 NVDSFPHQERLT------------------------------------------------------------EGTIDVWW 820
Cdd:pfam03522  158 TSNSKQDDDKSKlskkdsnlslspdkstknpsgkdssksdklkkkspsiilrtasnekeilnnitqfqkkqkKGTIDVWW 237
                          250       260       270
                   ....*....|....*....|....*....|..
gi 528520540   821 IVHDGGMLMLLPFLLRQHKVWKKCKMRIFTVA 852
Cdd:pfam03522  238 LYDDGGLTLLLPYILSTRSKWSDCKLRVFALG 269
AA_permease_2 pfam13520
Amino acid permease;
390-615 3.01e-14

Amino acid permease;


Pssm-ID: 404414 [Multi-domain]  Cd Length: 427  Bit Score: 76.19  E-value: 3.01e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540   390 FFTLLVGIYfpSVTGIMAGSNRSGdlRDAQRSIPIGTILAIATTTIIYL--SCVVLFGACIEGVVLRD-------KFGDS 460
Cdd:pfam13520  191 FAGFLGVLW--SFTGFESAANVSE--EVKKRNVPKAIFIGVIIVGVLYIlvNIAFFGVVPDDEIALSSglgqvaaLLFQA 266
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540   461 VKGNLVIGtlswpspwVIVIGSFFSCCGAGLQSLTGAPRLLQAIARDGIVPFLEVFGHGKANGEPTWALLLTALICESGI 540
Cdd:pfam13520  267 VGGKWGAI--------IVVILLALSLLGAVNTAIVGASRLLYALARDGVLPFSRFFAKVNKFGSPIRAIILTAILSLILL 338
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540   541 LIASLDAVAPI----LSMFFLMCYLFVNLACALqtLLRTPNWRPRFKYYHWALSFLGMSLCLALMFI-----------SS 605
Cdd:pfam13520  339 LLFLLSPAAYNallsLSAYGYLLSYLLPIIGLL--ILRKKRPDLGRIPGRWPVAIFGILFSLFLIVAlffppvgpatgSS 416
                          250
                   ....*....|
gi 528520540   606 WYYALVAMLI 615
Cdd:pfam13520  417 LNYAIILIVA 426
2A0308 TIGR00911
L-type amino acid transporter; [Transport and binding proteins, Amino acids, peptides and ...
413-606 3.80e-06

L-type amino acid transporter; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273332 [Multi-domain]  Cd Length: 501  Bit Score: 50.90  E-value: 3.80e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540   413 GDLRDAQRSIPIGTILAIATTTIIY-LSCVVLFGACIEGVVLRDKFGDSVKGNLVIGTLSWPSPwvIVIGsfFSCCGAGL 491
Cdd:TIGR00911  259 EEVKNPYRTLPIAIIISMPIVTFIYvLTNIAYFTVLSPEELLASLAVAVDFGERLLGVMSWAMP--ALVG--LSCFGSVN 334
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540   492 QSLTGAPRLLQAIARDGIVPFLEVFGHGKANgEPTWALLLTaliCESGILIASLDAVAPILSMFFLMCYLFVNLACALQT 571
Cdd:TIGR00911  335 GSLFSSSRLFFVGGREGHLPSLLSMIHVKRL-TPLPSLLIV---CTLTLLMLFSGDIYSLINLISFANWLFNALAVAGLL 410
                          170       180       190
                   ....*....|....*....|....*....|....*..
gi 528520540   572 LLR--TPNWRPRFKyYHWALSFLGMSLCLALMFISSW 606
Cdd:TIGR00911  411 WLRykRPEMNRPIK-VPLFFPVFFLLSCLFLIILSLY 446
2A0303 TIGR00906
cationic amino acid transport permease; [Transport and binding proteins, Amino acids, peptides ...
361-569 5.26e-03

cationic amino acid transport permease; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273330 [Multi-domain]  Cd Length: 557  Bit Score: 40.57  E-value: 5.26e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540   361 LVEKDIPSVSAS-DSSQDKYMPYVVNDI-----TAFFTLLvgiyfpsvtGIMAGSNRSGDLRDAQRSIPIGTILAIATTT 434
Cdd:TIGR00906  206 FTKADVANWSITeEKGAGGFMPYGFTGVlsgaaTCFFAFI---------GFDAIATTGEEVKNPQRAIPIGIVTSLLVCF 276
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528520540   435 IIYlscvVLFGACIEGVVLRDKFGDSVKGNLVIGTLSW-PSPWVIVIGSFFSCCGAGLQSLTGAPRLLQAIARDGIV-PF 512
Cdd:TIGR00906  277 VAY----FLMSAALTLMMPYYLLDPDAPFPVAFEYVGWdPAKYIVAVGALCGMSTSLLGGMFPLPRVIYAMARDGLLfKW 352
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 528520540   513 LEVFghGKANGEPTWALLLTALICESGILIASLDAVAPILSMFFLMCYLFVNlACAL 569
Cdd:TIGR00906  353 LAQI--NSKTKTPINATVVSGAIAALMAFLFDLKALVDLLSIGTLLAYSLVA-ACVL 406
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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