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Conserved domains on  [gi|528470084|ref|XP_005171182|]
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mitochondrial ubiquitin ligase activator of nfkb 1-A [Danio rerio]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
GIDE super family cl13864
E3 Ubiquitin ligase; This domain family is found in bacteria, archaea and eukaryotes, and is ...
 108-218 5.84e-09

E3 Ubiquitin ligase; This domain family is found in bacteria, archaea and eukaryotes, and is typically between 150 and 163 amino acids in length. There is a single completely conserved residue E that may be functionally important. GIDE is an E3 ubiquitin ligase which is involved in inducing apoptosis.


The actual alignment was detected with superfamily member pfam12483:

Pssm-ID: 403620  Cd Length: 160  Bit Score: 53.92  E-value: 5.84e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528470084  108 SWVSKKVNKQQTTNTVPFTLVQPGSFisdvcVRVDSPLEASGDFLQQVHRRVRNAKEGLMDAVLGEISG--EKPIALEER 185
Cdd:pfam12483  14 RWRRRSETLASNERSVPFYLRDDTGR-----VLVNVDPSGAEIELTVVYDRFEPSEGSLPSLLFGFFSGdlYLTLGYRYV 88

                          90       100       110
                  ....*....|....*....|....*....|...
gi 528470084  186 EDLLRVGVPLTAFGELVLEQEKIMRIQPPKDGR 218
Cdd:pfam12483  89 ERVLPPGTRLTVVGEAVSDEDGVLRIQKPEEKG 121
 
Name Accession Description Interval E-value
GIDE pfam12483
E3 Ubiquitin ligase; This domain family is found in bacteria, archaea and eukaryotes, and is ...
 108-218 5.84e-09

E3 Ubiquitin ligase; This domain family is found in bacteria, archaea and eukaryotes, and is typically between 150 and 163 amino acids in length. There is a single completely conserved residue E that may be functionally important. GIDE is an E3 ubiquitin ligase which is involved in inducing apoptosis.


Pssm-ID: 403620  Cd Length: 160  Bit Score: 53.92  E-value: 5.84e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528470084  108 SWVSKKVNKQQTTNTVPFTLVQPGSFisdvcVRVDSPLEASGDFLQQVHRRVRNAKEGLMDAVLGEISG--EKPIALEER 185
Cdd:pfam12483  14 RWRRRSETLASNERSVPFYLRDDTGR-----VLVNVDPSGAEIELTVVYDRFEPSEGSLPSLLFGFFSGdlYLTLGYRYV 88

                          90       100       110
                  ....*....|....*....|....*....|...
gi 528470084  186 EDLLRVGVPLTAFGELVLEQEKIMRIQPPKDGR 218
Cdd:pfam12483  89 ERVLPPGTRLTVVGEAVSDEDGVLRIQKPEEKG 121
 
Name Accession Description Interval E-value
GIDE pfam12483
E3 Ubiquitin ligase; This domain family is found in bacteria, archaea and eukaryotes, and is ...
 108-218 5.84e-09

E3 Ubiquitin ligase; This domain family is found in bacteria, archaea and eukaryotes, and is typically between 150 and 163 amino acids in length. There is a single completely conserved residue E that may be functionally important. GIDE is an E3 ubiquitin ligase which is involved in inducing apoptosis.


Pssm-ID: 403620  Cd Length: 160  Bit Score: 53.92  E-value: 5.84e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 528470084  108 SWVSKKVNKQQTTNTVPFTLVQPGSFisdvcVRVDSPLEASGDFLQQVHRRVRNAKEGLMDAVLGEISG--EKPIALEER 185
Cdd:pfam12483  14 RWRRRSETLASNERSVPFYLRDDTGR-----VLVNVDPSGAEIELTVVYDRFEPSEGSLPSLLFGFFSGdlYLTLGYRYV 88

                          90       100       110
                  ....*....|....*....|....*....|...
gi 528470084  186 EDLLRVGVPLTAFGELVLEQEKIMRIQPPKDGR 218
Cdd:pfam12483  89 ERVLPPGTRLTVVGEAVSDEDGVLRIQKPEEKG 121
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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