|
Name |
Accession |
Description |
Interval |
E-value |
| MCM |
smart00350 |
minichromosome maintenance proteins; |
38-534 |
0e+00 |
|
minichromosome maintenance proteins;
Pssm-ID: 214631 [Multi-domain] Cd Length: 509 Bit Score: 730.60 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 38 KPRVIREVRADSVGKLVTVRGIVTRVSEVKPKMVVATYTCDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSggRLYLQT 117
Cdd:smart00350 1 KPSSIRELRADHLGKLVRISGIVTRTSGVRPKLKRASFTCEKCGATLGPEIQSGRETEPTVCPPRECQSPTP--FSLNHE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 118 RgSRFIKFQEMKMQEHSDQVPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIFLPILrTGFRQVVQGLLSE--TYLEAHR 195
Cdd:smart00350 79 R-STFIDFQKIKLQESPEEVPVGQLPRSVDVILDGDLVDKAKPGDRVEVTGIYRNVP-YGFKLNTVKGLPVfaTYIEANH 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 196 IVK--MNKSEDDESGA----GELTREELRQIAE-EDFYEKLAASIAPEIYGHEDVKKALLLLLVGGVDQS-PRGMKIRGN 267
Cdd:smart00350 157 VRKldYKRSFEDSSFSvqslSDEEEEEIRKLSKdPDIYERLARSLAPSIYGHEDIKKAILLLLFGGVHKNlPDGMKIRGD 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 268 INICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEAD 347
Cdd:smart00350 237 INILLCGDPGTAKSQLLKYVEKTAPRAVYTTGKGSSAVGLTAAVTRDPETREFTLEAGALVLADNGVCCIDEFDKMDDSD 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 348 RTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYGRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLA 427
Cdd:smart00350 317 RTAIHEAMEQQTISIAKAGITTTLNARCSVLAAANPIGGRYDPKLTPEENIDLPAPILSRFDLLFVVLDEVDEERDRELA 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 428 QHITYVHQHSR-QPPSQFE-PLDMKLMRRYIAMCREK-QPMVPESLADYITAAYVEMRREAWASKDAT--YTSARTLLAI 502
Cdd:smart00350 397 KHVVDLHRYSHpEEDEAFEpPLSQEKLRKYIAYAREKiKPKLSEEAADKLVKAYVDLRKEDSQTESRSsiPITVRQLESI 476
|
490 500 510
....*....|....*....|....*....|..
gi 530385909 503 LRLSTALARLRMVDVVEKEDVNEAIRLMEMSK 534
Cdd:smart00350 477 IRLSEAHAKMRLSDVVEEADVEEAIRLLRESI 508
|
|
| MCM7 |
cd17758 |
DNA replication licensing factor Mcm7; Mcm7 is a helicase that play an important role in ... |
228-533 |
0e+00 |
|
DNA replication licensing factor Mcm7; Mcm7 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350664 [Multi-domain] Cd Length: 306 Bit Score: 610.18 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 228 KLAASIAPEIYGHEDVKKALLLLLVGGVDQSPRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGL 307
Cdd:cd17758 1 KLAASIAPEIYGHEDVKKALLLLLVGGVDKRGDGMKIRGDINICLMGDPGVAKSQLLKYICRIAPRSVYTTGRGSSGVGL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 308 TAAVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYGR 387
Cdd:cd17758 81 TAAVMKDPVTGEMTLEGGALVLADQGICCIDEFDKMDESDRTAIHEVMEQQTISIAKAGITTTLNARTSILAAANPAYGR 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 388 YNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHSRQPPSQFEPLDMKLMRRYIAMCREKQPMVP 467
Cdd:cd17758 161 YNPRRSPEQNINLPAALLSRFDLLFLILDKPDRDNDLRLAEHVTYVHQHNKQPDSDFEPLDPKLLRAYIALAKRKRPTVP 240
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 530385909 468 ESLADYITAAYVEMRREAWASKDATYTSARTLLAILRLSTALARLRMVDVVEKEDVNEAIRLMEMS 533
Cdd:cd17758 241 PALADYIVQAYVEMRQEAKRSKDFTFTTPRTLLAILRLSQALARLRLSDSVEIDDVEEALRLMEMS 306
|
|
| Mcm2 |
COG1241 |
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and ... |
36-531 |
3.31e-179 |
|
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and repair];
Pssm-ID: 440854 [Multi-domain] Cd Length: 682 Bit Score: 523.21 E-value: 3.31e-179
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 36 SNKPRV--IREVRADSVGKLVTVRGIVTRVSEVKPKMVVATYTCDQCGAETYQPIQSPTFMPLIMCPSQECQtnrsgGRL 113
Cdd:COG1241 88 TNLPETvpIRDIRSDHIGKLISVEGIVRKATEVKPKITEAAFECPRCGTETYVPQTGEKLQEPHECPGCGRQ-----GPF 162
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 114 YLQTRGSRFIKFQEMKMQEHSDQVPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIflpiLRTGFRQVVQGLLS--ETYL 191
Cdd:COG1241 163 KLLPEKSEFIDAQKIRIQEPPEDLPGGQQPQSIDVILEDDLVGEVRPGDRVTVTGI----LRIEQRTSGRGKSTifDLYL 238
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 192 EAHRIVKMNKSEDDEsgagELTREELRQIAE----EDFYEKLAASIAPEIYGHEDVKKALLL-----LLVGGVDqsprGM 262
Cdd:COG1241 239 EANSIEVEEKEFEEI----EITEEDEEKIKElskdPDIYEKIIASIAPSIYGYEEIKEAIALqlfggVPKVLPD----GS 310
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 263 KIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVLRDSVS-GELTLEGGALVLADQGVCCIDEFD 341
Cdd:COG1241 311 RIRGDIHILLVGDPGTAKSQLLRYAARLAPRGVYTSGKGSTAAGLTAAAVRDDFGtGRWTLEAGALVLADGGLACIDELD 390
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 342 KMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYGRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRD 421
Cdd:COG1241 391 KMREEDRSALHEAMEQQTISIAKAGIVATLNARCSVLAAANPKYGRFDPYEPIAEQIDLPPTLLSRFDLIFVLRDKPDEE 470
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 422 NDLRLAQHITYVHQHSRQPPSQFE--------PLDMKLMRRYIAMCREK-QPMVPESLADYITAAYVEMRREAWASKDAT 492
Cdd:COG1241 471 RDRELARHILKVHRAGELLEQEIEeeteevkpEIDPDLLRKYIAYARRNvFPVLTEEAKDLIEDFYVDMRKKGEDEDSPV 550
|
490 500 510
....*....|....*....|....*....|....*....
gi 530385909 493 YTSARTLLAILRLSTALARLRMVDVVEKEDVNEAIRLME 531
Cdd:COG1241 551 PITARQLEALIRLAEASARMRLSDTVTEEDAERAIRLVD 589
|
|
| minchrom_main_MCM |
NF040949 |
minichromosome maintenance protein MCM; |
21-531 |
1.41e-169 |
|
minichromosome maintenance protein MCM;
Pssm-ID: 468880 [Multi-domain] Cd Length: 681 Bit Score: 498.68 E-value: 1.41e-169
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 21 AELMRRFELYFQGPSSNKPrvIREVRADSVGKLVTVRGIVTRVSEVKPKMVVATYTCDQCGAETYQPiQSPTFMPLIMCP 100
Cdd:NF040949 81 AEEVAKFHVRFRNLPRTVP--LRDLRSEYIGKLIAVEGIVTRTTPVKPRIVKAVFRCRDCGCEFEWP-EEEEESYEIVEP 157
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 101 SQECQTNRSGGRLYLQTRGSRFIKFQEMKMQEHSDQVPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIFLPILRTGFRQ 180
Cdd:NF040949 158 PTVCPVCGKPGSFRLLQEKSKFIDWQKIVVQERPEELPPGQLPRSIEVVLEDDLVDTARPGDRVTVTGILRIKPDSSLKK 237
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 181 VVQGLLSeTYLEAHRIVKMNKsEDDESgagELTREELRQIAE----EDFYEKLAASIAPEIYGHEDVKKALLLLL-VGGV 255
Cdd:NF040949 238 GSRPIFK-NYIEANHIEVSQK-ELEEV---EITEEDEEKILElakdPWIREKIIASIAPSIYGHWEIKEAIALLLfGGVP 312
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 256 DQSPRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVLRDSVSGELTLEGGALVLADQGVC 335
Cdd:NF040949 313 KVLPDGTRIRGDIHVLIVGDPGTAKSQLLQYVARLAPRAVYTSGKGSTAAGLTAAVVRDKLTGEYYLEAGALVLADGGVA 392
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 336 CIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYGRYNPRRSLEQNIQLPAALLSRFDLLWLIQ 415
Cdd:NF040949 393 VIDEIDKMREEDRSAIHEAMEQQTVSIAKAGIVATLNARASVLAAGNPKFGRYDPNRSVAENIDLPPTILSRFDLIFVIR 472
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 416 DRPDRDNDLRLAQHITYVHQHSrqppSQFEP-LDMKLMRRYIAMCREK-QPMVPESLADYITAAYVEMRREAWASKD--- 490
Cdd:NF040949 473 DKPNEERDRRLARHILDVHSGK----EKVKPeIDPDLLKKYIAYARKYvRPKLTEEAKKLIEDFYVEMRKSSKSSEDpds 548
|
490 500 510 520
....*....|....*....|....*....|....*....|.
gi 530385909 491 ATYTSARTLLAILRLSTALARLRMVDVVEKEDVNEAIRLME 531
Cdd:NF040949 549 PIPITARQLEALIRLSEAHAKMRLKDEVTAEDAERAIRLML 589
|
|
| MCM |
pfam00493 |
MCM P-loop domain; |
215-434 |
3.51e-134 |
|
MCM P-loop domain;
Pssm-ID: 459830 [Multi-domain] Cd Length: 224 Bit Score: 391.12 E-value: 3.51e-134
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 215 EELRQIA-EEDFYEKLAASIAPEIYGHEDVKKALLLLLVG-GVDQSPRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAP 292
Cdd:pfam00493 3 EEIKELAkRPDIYDKLADSIAPSIYGHEDVKKAILLQLFGgVKKILPDGTRLRGDINVLLVGDPGTAKSQLLKYVEKIAP 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 293 RSQYTTGRGSSGVGLTAAVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLN 372
Cdd:pfam00493 83 RAVYTSGKGSSAAGLTAAVVRDPVTGEFVLEAGALVLADGGVCCIDEFDKMNDEDRVALHEAMEQQTISIAKAGIVATLN 162
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 530385909 373 ARCSILAAANPAYGRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVH 434
Cdd:pfam00493 163 ARCSILAAANPIFGRYDPKKSIAENINLPPPLLSRFDLIFVLLDKPDEEKDERLAKHIVDLH 224
|
|
| PTZ00111 |
PTZ00111 |
DNA replication licensing factor MCM4; Provisional |
30-533 |
1.66e-86 |
|
DNA replication licensing factor MCM4; Provisional
Pssm-ID: 173403 [Multi-domain] Cd Length: 915 Bit Score: 288.82 E-value: 1.66e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 30 YFQGPSSNKPRVIREVRADSvgkLVTVRGIVTRVSEVKPKMVVATYTC---DQCGAETYQPIQSPTFMPLIMCPSQE--- 103
Cdd:PTZ00111 209 LMNKPVSDCVGNLEPSMADS---LVQFSGTVVRQTWIVPEITMACFRCrgqKKIGLNDYQPCTCEHYEYVIQGEVNEpll 285
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 104 CQTNRSGGRLYLQTRGSRFIKFQEMKMQEHSDQVPVGNIP-RSITVLVEGENTRI-------------------AQPGDH 163
Cdd:PTZ00111 286 CNECNSKYTFELNHNMCVYSTKKIVKLLQSNSSLNNPDKDgLDNSVDNSGLNGEIymkdnevinlnlyddlidsVKTGDR 365
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 164 VSVTGIF--LPIlRTGFRQVVQGLLSETYLEA-H-RIVKMNKSEDDESG------AGELTREELRQIAE----EDFYEKL 229
Cdd:PTZ00111 366 VTVVGILkvTPI-RTSTTRRTLKSLYTYFVNViHvKVINSTNANQPEKGlkylgnENDFSDLQVYKILElsrnPMIYRIL 444
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 230 AASIAPEIYGHEDVKK----------ALLLLLVGGVDQSPRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTG 299
Cdd:PTZ00111 445 LDSFAPSIKARNNVKIgllcqlfsgnKNSSDFNKSPDACYKVDNFRGIINVLLCGDPGTAKSQLLHYTHLLSPRSIYTSG 524
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 300 RGSSGVGLTAAV-LRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSIL 378
Cdd:PTZ00111 525 KSSSSVGLTASIkFNESDNGRAMIQPGAVVLANGGVCCIDELDKCHNESRLSLYEVMEQQTVTIAKAGIVATLKAETAIL 604
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 379 AAANPAYGRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHI-----------------TY-------VH 434
Cdd:PTZ00111 605 ASCNPINSRYNKNKAVIENINISPSLFTRFDLIYLVLDHIDQDTDQLISLSIakdfllphmtgsgndedTYdrsntmhVE 684
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 435 QHSRQPPSQFEPLDMKLMRRYIAMCR-EKQPMVPESLADYITAAYVEMRREAWASKD----------------------- 490
Cdd:PTZ00111 685 DESLRSEKDYNKNDLDMLRMYIKFSKlHCFPKLSDEAKKVITREYVKMRQGNFQTSNldelehaqedddddlyyqssgtr 764
|
570 580 590 600
....*....|....*....|....*....|....*....|...
gi 530385909 491 ATYTSARTLLAILRLSTALARLRMVDVVEKEDVNEAIRLMEMS 533
Cdd:PTZ00111 765 MIYVSSRMISSIIRISVSLARMRLSTVVTPADALQAVQIVKSS 807
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| MCM |
smart00350 |
minichromosome maintenance proteins; |
38-534 |
0e+00 |
|
minichromosome maintenance proteins;
Pssm-ID: 214631 [Multi-domain] Cd Length: 509 Bit Score: 730.60 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 38 KPRVIREVRADSVGKLVTVRGIVTRVSEVKPKMVVATYTCDQCGAETYQPIQSPTFMPLIMCPSQECQTNRSggRLYLQT 117
Cdd:smart00350 1 KPSSIRELRADHLGKLVRISGIVTRTSGVRPKLKRASFTCEKCGATLGPEIQSGRETEPTVCPPRECQSPTP--FSLNHE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 118 RgSRFIKFQEMKMQEHSDQVPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIFLPILrTGFRQVVQGLLSE--TYLEAHR 195
Cdd:smart00350 79 R-STFIDFQKIKLQESPEEVPVGQLPRSVDVILDGDLVDKAKPGDRVEVTGIYRNVP-YGFKLNTVKGLPVfaTYIEANH 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 196 IVK--MNKSEDDESGA----GELTREELRQIAE-EDFYEKLAASIAPEIYGHEDVKKALLLLLVGGVDQS-PRGMKIRGN 267
Cdd:smart00350 157 VRKldYKRSFEDSSFSvqslSDEEEEEIRKLSKdPDIYERLARSLAPSIYGHEDIKKAILLLLFGGVHKNlPDGMKIRGD 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 268 INICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEAD 347
Cdd:smart00350 237 INILLCGDPGTAKSQLLKYVEKTAPRAVYTTGKGSSAVGLTAAVTRDPETREFTLEAGALVLADNGVCCIDEFDKMDDSD 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 348 RTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYGRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLA 427
Cdd:smart00350 317 RTAIHEAMEQQTISIAKAGITTTLNARCSVLAAANPIGGRYDPKLTPEENIDLPAPILSRFDLLFVVLDEVDEERDRELA 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 428 QHITYVHQHSR-QPPSQFE-PLDMKLMRRYIAMCREK-QPMVPESLADYITAAYVEMRREAWASKDAT--YTSARTLLAI 502
Cdd:smart00350 397 KHVVDLHRYSHpEEDEAFEpPLSQEKLRKYIAYAREKiKPKLSEEAADKLVKAYVDLRKEDSQTESRSsiPITVRQLESI 476
|
490 500 510
....*....|....*....|....*....|..
gi 530385909 503 LRLSTALARLRMVDVVEKEDVNEAIRLMEMSK 534
Cdd:smart00350 477 IRLSEAHAKMRLSDVVEEADVEEAIRLLRESI 508
|
|
| MCM7 |
cd17758 |
DNA replication licensing factor Mcm7; Mcm7 is a helicase that play an important role in ... |
228-533 |
0e+00 |
|
DNA replication licensing factor Mcm7; Mcm7 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350664 [Multi-domain] Cd Length: 306 Bit Score: 610.18 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 228 KLAASIAPEIYGHEDVKKALLLLLVGGVDQSPRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGL 307
Cdd:cd17758 1 KLAASIAPEIYGHEDVKKALLLLLVGGVDKRGDGMKIRGDINICLMGDPGVAKSQLLKYICRIAPRSVYTTGRGSSGVGL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 308 TAAVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYGR 387
Cdd:cd17758 81 TAAVMKDPVTGEMTLEGGALVLADQGICCIDEFDKMDESDRTAIHEVMEQQTISIAKAGITTTLNARTSILAAANPAYGR 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 388 YNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHSRQPPSQFEPLDMKLMRRYIAMCREKQPMVP 467
Cdd:cd17758 161 YNPRRSPEQNINLPAALLSRFDLLFLILDKPDRDNDLRLAEHVTYVHQHNKQPDSDFEPLDPKLLRAYIALAKRKRPTVP 240
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 530385909 468 ESLADYITAAYVEMRREAWASKDATYTSARTLLAILRLSTALARLRMVDVVEKEDVNEAIRLMEMS 533
Cdd:cd17758 241 PALADYIVQAYVEMRQEAKRSKDFTFTTPRTLLAILRLSQALARLRLSDSVEIDDVEEALRLMEMS 306
|
|
| Mcm2 |
COG1241 |
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and ... |
36-531 |
3.31e-179 |
|
DNA replicative helicase MCM subunit Mcm2, Cdc46/Mcm family [Replication, recombination and repair];
Pssm-ID: 440854 [Multi-domain] Cd Length: 682 Bit Score: 523.21 E-value: 3.31e-179
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 36 SNKPRV--IREVRADSVGKLVTVRGIVTRVSEVKPKMVVATYTCDQCGAETYQPIQSPTFMPLIMCPSQECQtnrsgGRL 113
Cdd:COG1241 88 TNLPETvpIRDIRSDHIGKLISVEGIVRKATEVKPKITEAAFECPRCGTETYVPQTGEKLQEPHECPGCGRQ-----GPF 162
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 114 YLQTRGSRFIKFQEMKMQEHSDQVPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIflpiLRTGFRQVVQGLLS--ETYL 191
Cdd:COG1241 163 KLLPEKSEFIDAQKIRIQEPPEDLPGGQQPQSIDVILEDDLVGEVRPGDRVTVTGI----LRIEQRTSGRGKSTifDLYL 238
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 192 EAHRIVKMNKSEDDEsgagELTREELRQIAE----EDFYEKLAASIAPEIYGHEDVKKALLL-----LLVGGVDqsprGM 262
Cdd:COG1241 239 EANSIEVEEKEFEEI----EITEEDEEKIKElskdPDIYEKIIASIAPSIYGYEEIKEAIALqlfggVPKVLPD----GS 310
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 263 KIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVLRDSVS-GELTLEGGALVLADQGVCCIDEFD 341
Cdd:COG1241 311 RIRGDIHILLVGDPGTAKSQLLRYAARLAPRGVYTSGKGSTAAGLTAAAVRDDFGtGRWTLEAGALVLADGGLACIDELD 390
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 342 KMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYGRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRD 421
Cdd:COG1241 391 KMREEDRSALHEAMEQQTISIAKAGIVATLNARCSVLAAANPKYGRFDPYEPIAEQIDLPPTLLSRFDLIFVLRDKPDEE 470
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 422 NDLRLAQHITYVHQHSRQPPSQFE--------PLDMKLMRRYIAMCREK-QPMVPESLADYITAAYVEMRREAWASKDAT 492
Cdd:COG1241 471 RDRELARHILKVHRAGELLEQEIEeeteevkpEIDPDLLRKYIAYARRNvFPVLTEEAKDLIEDFYVDMRKKGEDEDSPV 550
|
490 500 510
....*....|....*....|....*....|....*....
gi 530385909 493 YTSARTLLAILRLSTALARLRMVDVVEKEDVNEAIRLME 531
Cdd:COG1241 551 PITARQLEALIRLAEASARMRLSDTVTEEDAERAIRLVD 589
|
|
| minchrom_main_MCM |
NF040949 |
minichromosome maintenance protein MCM; |
21-531 |
1.41e-169 |
|
minichromosome maintenance protein MCM;
Pssm-ID: 468880 [Multi-domain] Cd Length: 681 Bit Score: 498.68 E-value: 1.41e-169
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 21 AELMRRFELYFQGPSSNKPrvIREVRADSVGKLVTVRGIVTRVSEVKPKMVVATYTCDQCGAETYQPiQSPTFMPLIMCP 100
Cdd:NF040949 81 AEEVAKFHVRFRNLPRTVP--LRDLRSEYIGKLIAVEGIVTRTTPVKPRIVKAVFRCRDCGCEFEWP-EEEEESYEIVEP 157
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 101 SQECQTNRSGGRLYLQTRGSRFIKFQEMKMQEHSDQVPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIFLPILRTGFRQ 180
Cdd:NF040949 158 PTVCPVCGKPGSFRLLQEKSKFIDWQKIVVQERPEELPPGQLPRSIEVVLEDDLVDTARPGDRVTVTGILRIKPDSSLKK 237
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 181 VVQGLLSeTYLEAHRIVKMNKsEDDESgagELTREELRQIAE----EDFYEKLAASIAPEIYGHEDVKKALLLLL-VGGV 255
Cdd:NF040949 238 GSRPIFK-NYIEANHIEVSQK-ELEEV---EITEEDEEKILElakdPWIREKIIASIAPSIYGHWEIKEAIALLLfGGVP 312
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 256 DQSPRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVLRDSVSGELTLEGGALVLADQGVC 335
Cdd:NF040949 313 KVLPDGTRIRGDIHVLIVGDPGTAKSQLLQYVARLAPRAVYTSGKGSTAAGLTAAVVRDKLTGEYYLEAGALVLADGGVA 392
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 336 CIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYGRYNPRRSLEQNIQLPAALLSRFDLLWLIQ 415
Cdd:NF040949 393 VIDEIDKMREEDRSAIHEAMEQQTVSIAKAGIVATLNARASVLAAGNPKFGRYDPNRSVAENIDLPPTILSRFDLIFVIR 472
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 416 DRPDRDNDLRLAQHITYVHQHSrqppSQFEP-LDMKLMRRYIAMCREK-QPMVPESLADYITAAYVEMRREAWASKD--- 490
Cdd:NF040949 473 DKPNEERDRRLARHILDVHSGK----EKVKPeIDPDLLKKYIAYARKYvRPKLTEEAKKLIEDFYVEMRKSSKSSEDpds 548
|
490 500 510 520
....*....|....*....|....*....|....*....|.
gi 530385909 491 ATYTSARTLLAILRLSTALARLRMVDVVEKEDVNEAIRLME 531
Cdd:NF040949 549 PIPITARQLEALIRLSEAHAKMRLKDEVTAEDAERAIRLML 589
|
|
| MCM |
cd17706 |
MCM helicase family; MCM helicases are a family of helicases that play an important role in ... |
228-533 |
2.47e-140 |
|
MCM helicase family; MCM helicases are a family of helicases that play an important role in replication and homologous recombination repair. The heterohexameric ring-shaped Mcm2-7 complex is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases. Mcm8 and Mcm9, form a complex required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350658 [Multi-domain] Cd Length: 311 Bit Score: 410.20 E-value: 2.47e-140
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 228 KLAASIAPEIYGHEDVKKALLLLLVGGVDQS-PRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVG 306
Cdd:cd17706 1 ILADSIAPSIYGHEDVKKAVLLQLFGGVQKIlEDGTRIRGDIHILLVGDPGTAKSQILKYVLKIAPRGVYTSGKGSSGAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 307 LTAAVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYG 386
Cdd:cd17706 81 LTAAVVRDSETGEWYLEAGALVLADGGVCCIDEFDKMKELDRTALHEAMEQQTISIAKAGIVTTLNARCSILAAANPKGG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 387 RYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHS-----RQPPSQFEPLDMKLMRRYIAMCRE 461
Cdd:cd17706 161 RYNPKLSPIENINLPSPLLSRFDLIFVIRDDPDEERDEELAEHIIDLHRGSdpeeqVKPEEDGIPIDIELLRKYILYARQ 240
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 530385909 462 KQPMVPESLADYITAAYVEMRREAwASKDATYTSARTLLAILRLSTALARLRMVDVVEKEDVNEAIRLMEMS 533
Cdd:cd17706 241 IHPKISEEAREKLVRWYVELRKES-ERRSTIPITARQLESVIRLAEAHAKMRLSEVVTEEDVEEAIRLVRHS 311
|
|
| MCM |
pfam00493 |
MCM P-loop domain; |
215-434 |
3.51e-134 |
|
MCM P-loop domain;
Pssm-ID: 459830 [Multi-domain] Cd Length: 224 Bit Score: 391.12 E-value: 3.51e-134
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 215 EELRQIA-EEDFYEKLAASIAPEIYGHEDVKKALLLLLVG-GVDQSPRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAP 292
Cdd:pfam00493 3 EEIKELAkRPDIYDKLADSIAPSIYGHEDVKKAILLQLFGgVKKILPDGTRLRGDINVLLVGDPGTAKSQLLKYVEKIAP 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 293 RSQYTTGRGSSGVGLTAAVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLN 372
Cdd:pfam00493 83 RAVYTSGKGSSAAGLTAAVVRDPVTGEFVLEAGALVLADGGVCCIDEFDKMNDEDRVALHEAMEQQTISIAKAGIVATLN 162
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 530385909 373 ARCSILAAANPAYGRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVH 434
Cdd:pfam00493 163 ARCSILAAANPIFGRYDPKKSIAENINLPPPLLSRFDLIFVLLDKPDEEKDERLAKHIVDLH 224
|
|
| MCM4 |
cd17755 |
DNA replication licensing factor Mcm4; Mcm4 is a helicase that play an important role in ... |
228-530 |
2.93e-122 |
|
DNA replication licensing factor Mcm4; Mcm4 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350661 [Multi-domain] Cd Length: 309 Bit Score: 364.06 E-value: 2.93e-122
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 228 KLAASIAPEIYGHEDVKKALLLLL--VGGVDQSPRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGV 305
Cdd:cd17755 1 RLARSIAPSIYELEDVKKGILLQLfgGTRKDFTKTGGKYRGDINILLCGDPGTSKSQLLQYVHKISPRGVYTSGKGSSAV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 306 GLTAAVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAY 385
Cdd:cd17755 81 GLTAYVTRDPDTKQLVLESGALVLSDGGICCIDEFDKMSDSTRSVLHEVMEQQTLSIAKAGIITTLNARTSILASANPIG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 386 GRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHSRQPPSQFEPLDMKLMRRYIAMCREK-QP 464
Cdd:cd17755 161 SRYNPKLTVVENIDLPPTLLSRFDLIYLVLDKVDEKYDRRLAKHLVSLYLEDTPEHIQDEVLDVEVLTDYISYAREHiHP 240
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 530385909 465 MVPESLADYITAAYVEMRReAWASKDATYTSA-RTLLAILRLSTALARLRMVDVVEKEDVNEAIRLM 530
Cdd:cd17755 241 KLSEEAAQELVQAYVDMRK-MGSDARKRITATpRQLESLIRLAEAHAKMRLSNVVEAEDVEEAVRLI 306
|
|
| MCM5 |
cd17756 |
DNA replication licensing factor Mcm5; Mcm5 is a helicase that play an important role in ... |
228-533 |
1.94e-121 |
|
DNA replication licensing factor Mcm5; Mcm5 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350662 [Multi-domain] Cd Length: 317 Bit Score: 362.09 E-value: 1.94e-121
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 228 KLAASIAPEIYGHEDVKKALLLLLVGGVDQS-PRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVG 306
Cdd:cd17756 1 IISKSIAPSIYGNEDIKKAIACLLFGGSRKRlPDGMRLRGDINVLLLGDPGTAKSQLLKFVEKVAPIGVYTSGKGSSAAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 307 LTAAVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYG 386
Cdd:cd17756 81 LTASVMRDPSTREFYLEGGAMVLADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRTSVLAAANPVFG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 387 RYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHSR--QPPSQFEP-LDMKLMRRYIAMCREK- 462
Cdd:cd17756 161 RYDDLKTPGDNIDFQTTILSRFDMIFIVKDKHDEERDITIAKHVINIHASARkaSQSQENEGeIPISKLKRYIAYCRAKc 240
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 530385909 463 QPMVPESLADYITAAYVEMRREAWASKDATYTSA------RTLLAILRLSTALARLRMVDVVEKEDVNEAIRLMEMS 533
Cdd:cd17756 241 APRLSEEAAEKLSNHYVTIRKDVRQNELESDNRSsipitvRQLEAIIRISESLAKMELSPIATEKHVEEAIRLFQVS 317
|
|
| MCM_arch |
cd17761 |
archaeal MCM protein; archaeal MCM proteins form a homohexameric ring homologous to the ... |
227-530 |
1.01e-119 |
|
archaeal MCM protein; archaeal MCM proteins form a homohexameric ring homologous to the eukaryotic Mcm2-7 helicase and also function as the replicative helicase at the replication fork
Pssm-ID: 350667 [Multi-domain] Cd Length: 308 Bit Score: 357.53 E-value: 1.01e-119
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 227 EKLAASIAPEIYGHEDVKKALLLLL-VGGVDQSPRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGV 305
Cdd:cd17761 1 EKIISSIAPSIYGHEDVKEAIALQLfGGVPKVLPDGTRIRGDIHILLVGDPGTAKSQLLKYVSKVAPRAVYTTGKGSTAA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 306 GLTAAVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAY 385
Cdd:cd17761 81 GLTAAVVRDEGTGEWYLEAGALVLADKGIAVVDEIDKMRKEDRSALHEAMEQQTISIAKAGIVATLNARAAVLAAANPKF 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 386 GRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHSRqpPSQFEP-LDMKLMRRYIAMCREK-Q 463
Cdd:cd17761 161 GRFDSYRPVAEQIDLPPTLLSRFDLIFVLKDTPNEEKDRRLANHILDTHSGGE--MREIKPeIDPDLLRKYIAYARKNvR 238
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 530385909 464 PMVPESLADYITAAYVEMRREAWASKDATYTSARTLLAILRLSTALARLRMVDVVEKEDVNEAIRLM 530
Cdd:cd17761 239 PVLTEEAKQLIKDFYVEMRKSGQETPSPVPITARQLEALVRLSEASARMRLSQEVTLEDAERAIRIM 305
|
|
| MCM6 |
cd17757 |
DNA replication licensing factor Mcm6; Mcm6 is a helicase that play an important role in ... |
228-533 |
4.83e-118 |
|
DNA replication licensing factor Mcm6; Mcm6 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350663 [Multi-domain] Cd Length: 307 Bit Score: 353.21 E-value: 4.83e-118
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 228 KLAASIAPEIYGHEDVKKALLLLLVG-GVDQSPRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVG 306
Cdd:cd17757 1 NLVRSIAPSIYGHEEVKKGILLMLLGgVHKITREGISLRGDINVCIVGDPSTAKSQFLKYVEEFSPRAVYTSGKASSAAG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 307 LTAAVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYG 386
Cdd:cd17757 81 LTAAVVRDEETGDFVIEAGALMLADNGICCIDEFDKMDIKDQVAIHEAMEQQTISITKAGIQATLNARTSILAAANPVGG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 387 RYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHItyVHQHSRQPPSQFEPLDMKLMRRYIAMCREKQPMV 466
Cdd:cd17757 161 RYDRSKSLKQNINISAPIMSRFDLFFVLLDECNEVTDYAIASHI--VDLHSKREEAIEPPFTAEQLKRYIAYARTFKPKL 238
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 530385909 467 PESLADYITAAYVEMR-REAWASKDATY-TSARTLLAILRLSTALARLRMVDVVEKEDVNEAIRLMEMS 533
Cdd:cd17757 239 TKEAKDELVEQYKELRqDDASGSTRSSYrITVRQLESLIRLSEAIARLHCSDEVTPEHVEEAARLLKKS 307
|
|
| MCM2 |
cd17753 |
DNA replication licensing factor Mcm2; Mcm2 is a helicase that play an important role in ... |
228-530 |
9.94e-118 |
|
DNA replication licensing factor Mcm2; Mcm2 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350659 [Multi-domain] Cd Length: 325 Bit Score: 352.91 E-value: 9.94e-118
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 228 KLAASIAPEIYGHEDVKKALLLLLVGGVDQSPRGM-KIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVG 306
Cdd:cd17753 1 RIINSIAPSIYGHDDIKTAIALALFGGVAKNPGGKhRIRGDINVLLLGDPGTAKSQFLKYVEKTAHRAVFTTGQGASAVG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 307 LTAAVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYG 386
Cdd:cd17753 81 LTASVRKDPVTKEWTLEGGALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCSVIAAANPIGG 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 387 RYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHItyVHQHSRQPPS--------------------QFEP 446
Cdd:cd17753 161 RYNPTLTFAQNVNLTEPILSRFDILCVVRDTVDPEEDERLAKFV--VGSHVRSHPEndedregeeeknqrqrpketKVEP 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 447 LDMKLMRRYIAMCREK-QPMVPESLADYITAAYVEMRREAWASKDATYTsARTLLAILRLSTALARLRMVDVVEKEDVNE 525
Cdd:cd17753 239 IPQELLRKYIHYAREKvRPKLNQMDMDKVSRVYADLRKESMATGSLPIT-VRHLESIIRISEAHAKMHLREYVSEEDVDM 317
|
....*
gi 530385909 526 AIRLM 530
Cdd:cd17753 318 AIRVM 322
|
|
| MCM3 |
cd17754 |
DNA replication licensing factor Mcm3; Mcm3 is a helicase that play an important role in ... |
229-530 |
2.26e-113 |
|
DNA replication licensing factor Mcm3; Mcm3 is a helicase that play an important role in replication. It is part of the heterohexameric ring-shaped Mcm2-7 complex, which is part of the replicative helicase that unwinds parental double-stranded DNA at a replication fork to provide single-stranded DNA templates for the replicative polymerases.
Pssm-ID: 350660 [Multi-domain] Cd Length: 299 Bit Score: 340.98 E-value: 2.26e-113
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 229 LAASIAPEIYGHEDVKKALLLLLVGGVDQS-PRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGL 307
Cdd:cd17754 2 LSKSLAPSIYGHEYIKKAILLMLLGGVEKNlENGSHLRGDINILLVGDPSVAKSQLLRYVLNTAPLAIATTGRGSSGVGL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 308 TAAVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYGR 387
Cdd:cd17754 82 TAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDIDRVAIHEVMEQQTVTIAKAGIHASLNARCSVLAAANPVYGR 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 388 YNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHsrqppsqfepldMKLMRRYIAMCREK-QPMV 466
Cdd:cd17754 162 YDVYKTPMENIGLPDSLLSRFDLLFIVLDDIDEERDRSISEHVLRMHRY------------IKFLRKYIHYAKERiKPKL 229
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 530385909 467 PESLADYITAAYVEMRREAWASKDATYTS---ARTLLAILRLSTALARLRMVDVVEKEDVNEAIRLM 530
Cdd:cd17754 230 TQEAAEYIAEEYADLRNDDNTKTDKARTSpitARTLETLIRLATAHAKARLSKTVDKVDAEVALNLL 296
|
|
| PTZ00111 |
PTZ00111 |
DNA replication licensing factor MCM4; Provisional |
30-533 |
1.66e-86 |
|
DNA replication licensing factor MCM4; Provisional
Pssm-ID: 173403 [Multi-domain] Cd Length: 915 Bit Score: 288.82 E-value: 1.66e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 30 YFQGPSSNKPRVIREVRADSvgkLVTVRGIVTRVSEVKPKMVVATYTC---DQCGAETYQPIQSPTFMPLIMCPSQE--- 103
Cdd:PTZ00111 209 LMNKPVSDCVGNLEPSMADS---LVQFSGTVVRQTWIVPEITMACFRCrgqKKIGLNDYQPCTCEHYEYVIQGEVNEpll 285
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 104 CQTNRSGGRLYLQTRGSRFIKFQEMKMQEHSDQVPVGNIP-RSITVLVEGENTRI-------------------AQPGDH 163
Cdd:PTZ00111 286 CNECNSKYTFELNHNMCVYSTKKIVKLLQSNSSLNNPDKDgLDNSVDNSGLNGEIymkdnevinlnlyddlidsVKTGDR 365
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 164 VSVTGIF--LPIlRTGFRQVVQGLLSETYLEA-H-RIVKMNKSEDDESG------AGELTREELRQIAE----EDFYEKL 229
Cdd:PTZ00111 366 VTVVGILkvTPI-RTSTTRRTLKSLYTYFVNViHvKVINSTNANQPEKGlkylgnENDFSDLQVYKILElsrnPMIYRIL 444
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 230 AASIAPEIYGHEDVKK----------ALLLLLVGGVDQSPRGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTG 299
Cdd:PTZ00111 445 LDSFAPSIKARNNVKIgllcqlfsgnKNSSDFNKSPDACYKVDNFRGIINVLLCGDPGTAKSQLLHYTHLLSPRSIYTSG 524
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 300 RGSSGVGLTAAV-LRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSIL 378
Cdd:PTZ00111 525 KSSSSVGLTASIkFNESDNGRAMIQPGAVVLANGGVCCIDELDKCHNESRLSLYEVMEQQTVTIAKAGIVATLKAETAIL 604
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 379 AAANPAYGRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHI-----------------TY-------VH 434
Cdd:PTZ00111 605 ASCNPINSRYNKNKAVIENINISPSLFTRFDLIYLVLDHIDQDTDQLISLSIakdfllphmtgsgndedTYdrsntmhVE 684
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 435 QHSRQPPSQFEPLDMKLMRRYIAMCR-EKQPMVPESLADYITAAYVEMRREAWASKD----------------------- 490
Cdd:PTZ00111 685 DESLRSEKDYNKNDLDMLRMYIKFSKlHCFPKLSDEAKKVITREYVKMRQGNFQTSNldelehaqedddddlyyqssgtr 764
|
570 580 590 600
....*....|....*....|....*....|....*....|...
gi 530385909 491 ATYTSARTLLAILRLSTALARLRMVDVVEKEDVNEAIRLMEMS 533
Cdd:PTZ00111 765 MIYVSSRMISSIIRISVSLARMRLSTVVTPADALQAVQIVKSS 807
|
|
| MCM9 |
cd17760 |
DNA helicase Mcm9; Mcm9 plays an important role homologous recombination repair. It forms a ... |
229-533 |
5.50e-82 |
|
DNA helicase Mcm9; Mcm9 plays an important role homologous recombination repair. It forms a complex with Mcm8 that is required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350666 [Multi-domain] Cd Length: 299 Bit Score: 259.79 E-value: 5.50e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 229 LAASIAPEIYGHEDVKKALLLLLV---GGVDQSprGMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGV 305
Cdd:cd17760 2 ILASLCPQVFGLYNVKLAVAMVLAggvQRIDAS--GTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTAGIGSTSA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 306 GLTAAVLRDSvsGELTLEGGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAy 385
Cdd:cd17760 80 GLTVTAVKDG--GEWNLEAGALVLADGGLCCIDEFNSLKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAATNPK- 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 386 GRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITyvhqHSRQPPSQFEPL-DMKLMRRYIAMCREKQP 464
Cdd:cd17760 157 GQYDPNESISVNIALASPLLSRFDLVLVLLDTKNEDWDRIISSFIL----ENKGEPSKSSKLwSMEKMRTYFCLIKNLRP 232
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 530385909 465 MVPESlADYITAAYVEMRREAwASKDATYTSARTLLAILRLSTALARLRMVDVVEKEDVNEAIRLMEMS 533
Cdd:cd17760 233 VLSDE-ANAILLRYYQLQRQS-DCRNAARTTIRMLESLIRLAEAHARLMFRETVTEEDAITVVSVMESS 299
|
|
| MCM8 |
cd17759 |
DNA helicase Mcm8; Mcm8 plays an important role homologous recombination repair. It forms a ... |
229-533 |
4.65e-74 |
|
DNA helicase Mcm8; Mcm8 plays an important role homologous recombination repair. It forms a complex with Mcm9 that is required for homologous recombination (HR) repair induced by DNA interstrand crosslinks (ICLs).
Pssm-ID: 350665 [Multi-domain] Cd Length: 289 Bit Score: 238.59 E-value: 4.65e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 229 LAASIAPEIYGHEDVKKALLLL----LVGGVDQSPRgMKIRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSG 304
Cdd:cd17759 2 IVNSLCPAIYGHELVKAGLLLSlfggKQKYADDKNR-IPIRGDPHVLIVGDPGLGKSQMLQAACNIAPRGVYVCGNTTTT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 305 VGLTAAVLRDSVSGELTLEGGALVLADQGVCCIDEFDKMAEaDRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPA 384
Cdd:cd17759 81 SGLTVTLTKDGRSGDFALEAGALVLGDQGICGIDEFDKMGS-QHQALLEAMEQQSVSLAKAGVVCSLPARTSVIAAANPV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 385 YGRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHityvhqhsrqppsqfepldMKLMRRYIAMCR-EKQ 463
Cdd:cd17759 160 GGHYNKGKTVSENLKMGPALLSRFDLVFILLDTPSEEHDHLLSEH-------------------HQLLRKYISYARqYVN 220
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 464 PMVPESLADYITAAYVEMRREAwASKDATYTSARTLLAILRLSTALARLRMVDVVEKEDVNEAIRLMEMS 533
Cdd:cd17759 221 PVLSKDASEALQEFYLELRKQN-QLADSSPITTRQLESLIRLTEARARLELREEATKEDAEDVIEIMKES 289
|
|
| MCM_OB |
pfam17207 |
MCM OB domain; This family contains an OB-fold found within MCM proteins. This domain contains ... |
42-173 |
6.23e-52 |
|
MCM OB domain; This family contains an OB-fold found within MCM proteins. This domain contains an insertion at the zinc binding motif.
Pssm-ID: 465381 [Multi-domain] Cd Length: 126 Bit Score: 174.21 E-value: 6.23e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 42 IREVRADSVGKLVTVRGIVTRVSEVKPKMVVATYTCDQCGAETYQPIQSPTfmpliMCPSQECQtnrSGGRLYLQTRGSR 121
Cdd:pfam17207 2 IRDLRSEHIGKLVSVSGIVTRTSEVRPKLKKATFTCRKCGHTVGVKITEPT-----KCPNPECG---NKDPFKLVHEKSK 73
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 530385909 122 FIKFQEMKMQEHSDQVPVGNIPRSITVLVEGENTRIAQPGDHVSVTGIFLPI 173
Cdd:pfam17207 74 FVDFQKIKIQESPEEVPAGELPRSLDVILDDDLVDRVKPGDRVTVTGIYRVV 125
|
|
| MCM_lid |
pfam17855 |
MCM AAA-lid domain; This entry represents the AAA-lid domain found in MCM proteins. |
451-534 |
1.81e-26 |
|
MCM AAA-lid domain; This entry represents the AAA-lid domain found in MCM proteins.
Pssm-ID: 465534 [Multi-domain] Cd Length: 86 Bit Score: 103.01 E-value: 1.81e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 451 LMRRYIAMCREK-QPMVPESLADYITAAYVEMRREAWASKDATYTSARTLLAILRLSTALARLRMVDVVEKEDVNEAIRL 529
Cdd:pfam17855 2 LLRKYIAYAREKiKPKLSEEAREKLVDAYVELRKESTGSGSSIPITVRQLESLIRLSEAHAKMRLSEIVTEEDVEEAIRL 81
|
....*
gi 530385909 530 MEMSK 534
Cdd:pfam17855 82 LKESL 86
|
|
| AAA_5 |
pfam07728 |
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not ... |
269-408 |
1.02e-05 |
|
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.
Pssm-ID: 400191 [Multi-domain] Cd Length: 135 Bit Score: 45.36 E-value: 1.02e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 269 NICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSgvGLTAAVLRDSVS---GELTLEGGALVLADQ--GVCCIDEFDKm 343
Cdd:pfam07728 1 GVLLVGPPGTGKTELAERLAAALSNRPVFYVQLTR--DTTEEDLFGRRNidpGGASWVDGPLVRAARegEIAVLDEINR- 77
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 530385909 344 AEADRTAI-HEVMEQQTISIAKAGILTTLNARC-SILAAANPAYGRYNPrrsleqniqLPAALLSRF 408
Cdd:pfam07728 78 ANPDVLNSlLSLLDERRLLLPDGGELVKAAPDGfRLIATMNPLDRGLNE---------LSPALRSRF 135
|
|
| MoxR |
COG0714 |
MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway ... |
337-523 |
5.52e-05 |
|
MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis
Pssm-ID: 440478 [Multi-domain] Cd Length: 292 Bit Score: 45.54 E-value: 5.52e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 337 IDEFDKmaeAD-RT--AIHEVMEQQTISIAKAGIltTLNARCSILAAANP--AYGRYnprrsleqniQLPAALLSRFDL- 410
Cdd:COG0714 100 ADEINR---APpKTqsALLEAMEERQVTIPGGTY--KLPEPFLVIATQNPieQEGTY----------PLPEAQLDRFLLk 164
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530385909 411 LWLiqDRPDRDNDLRLaqhityVHQHSRQPPSQFEPLdmkLMRRYIAMCRE--KQPMVPESLADYITAAYVEMRREAWAS 488
Cdd:COG0714 165 LYI--GYPDAEEEREI------LRRHTGRHLAEVEPV---LSPEELLALQElvRQVHVSEAVLDYIVDLVRATREHPDLR 233
|
170 180 190
....*....|....*....|....*....|....*
gi 530385909 489 KDAtytSARTLLAILRLSTALARLRMVDVVEKEDV 523
Cdd:COG0714 234 KGP---SPRASIALLRAARALALLDGRDYVTPDDV 265
|
|
| |
