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Conserved domains on  [gi|530391275|ref|XP_005252124|]
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methylglutaconyl-CoA hydratase, mitochondrial isoform X2 [Homo sapiens]

Protein Classification

Clp protease/crotonase-like domain-containing protein( domain architecture ID 581041)

Clp protease/crotonase-like domain-containing protein similar to Oryza sativa enoyl-CoA delta isomerase which plays a role in fatty acid metabolism, which involves stabilization of an enolate anion intermediate derived from an acyl-CoA substrate

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
crotonase-like super family cl23717
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
 99-333 3.77e-77

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


The actual alignment was detected with superfamily member PRK07657:

Pssm-ID: 474030 [Multi-domain]  Cd Length: 260  Bit Score: 236.94  E-value: 3.77e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275  99 IVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGIFCAGADLKERAKMSSSEVGPFVSKIRAVINDI 178
Cdd:PRK07657  14 VVKITLNRPRAANALSLALLEELQNILTQINEEANVRVVILTGAGEKAFCAGADLKERAGMNEEQVRHAVSLIRTTMEMV 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 179 ANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEA 258
Cdd:PRK07657  94 EQLPQPVIAAINGIALGGGLELALACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISAQEA 173

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 259 KAVGLISHVLEQNQEGDaayrKALDLAREFLPQGPVAMRVAKLAINQGME----------------TIPTKDRLEGLLAF 322
Cdd:PRK07657 174 KEIGLVEFVVPAHLLEE----KAIEIAEKIASNGPIAVRQAKEAISNGIQvdlhtglqiekqayegTIPTKDRLEGLQAF 249

                        250
                 ....*....|.
gi 530391275 323 KEKRPPRYKGE 333
Cdd:PRK07657 250 KEKRKPMYKGE 260
 
Name Accession Description Interval E-value
PRK07657 PRK07657
enoyl-CoA hydratase; Provisional
 99-333 3.77e-77

enoyl-CoA hydratase; Provisional


Pssm-ID: 181069 [Multi-domain]  Cd Length: 260  Bit Score: 236.94  E-value: 3.77e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275  99 IVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGIFCAGADLKERAKMSSSEVGPFVSKIRAVINDI 178
Cdd:PRK07657  14 VVKITLNRPRAANALSLALLEELQNILTQINEEANVRVVILTGAGEKAFCAGADLKERAGMNEEQVRHAVSLIRTTMEMV 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 179 ANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEA 258
Cdd:PRK07657  94 EQLPQPVIAAINGIALGGGLELALACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISAQEA 173

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 259 KAVGLISHVLEQNQEGDaayrKALDLAREFLPQGPVAMRVAKLAINQGME----------------TIPTKDRLEGLLAF 322
Cdd:PRK07657 174 KEIGLVEFVVPAHLLEE----KAIEIAEKIASNGPIAVRQAKEAISNGIQvdlhtglqiekqayegTIPTKDRLEGLQAF 249

                        250
                 ....*....|.
gi 530391275 323 KEKRPPRYKGE 333
Cdd:PRK07657 250 KEKRKPMYKGE 260
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
 98-327 1.54e-54

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 178.44  E-value: 1.54e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275  98 RIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEvPGIFCAGADLKE-RAKMSSSEVGPFVSKIRAVIN 176
Cdd:COG1024    8 GVATITLNRPEKLNALSLEMLAELAAALDEAEADPDVRVVVLTGA-GKAFCAGADLKElAAAADPEEARAFARGLQRLFR 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 177 DIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGK 256
Cdd:COG1024   87 ALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRLVGLARAKELLLTGRRIDAE 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 257 EAKAVGLISHVLEQnqegDAAYRKALDLAREFLPQGPVAMRVAKLAINQGMET----------------IPTKDRLEGLL 320
Cdd:COG1024  167 EALELGLVNRVVPD----DELLAAALALAARLAAGPPLALAATKRALNAALEApldealeleaeafaelFASEDAREGIA 242


                 ....*..
gi 530391275 321 AFKEKRP 327
Cdd:COG1024  243 AFLEKRK 249
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
 98-287 1.59e-46

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 156.18  E-value: 1.59e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275  98 RIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEvPGIFCAGADLKERAKMSSS--EVGPFVSKIRAVI 175
Cdd:cd06558    8 GVATITLNRPEKRNALSLEMLDELAAALDEAEADPDVRVVVLTGA-GKAFCAGADLKELAALSDAgeEARAFIRELQELL 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 176 NDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDG 255
Cdd:cd06558   87 RALLRLPKPVIAAVNGAALGGGLELALACDIRIAAEDAKFGLPEVKLGLVPGGGGTQRLPRLVGPARARELLLTGRRISA 166

                        170       180       190
                 ....*....|....*....|....*....|..
gi 530391275 256 KEAKAVGLISHVLEQnqegDAAYRKALDLARE 287
Cdd:cd06558  167 EEALELGLVDEVVPD----EELLAAALELARR 194
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
 99-332 1.88e-40

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 142.11  E-value: 1.88e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275   99 IVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSeVPGIFCAGADLKERAKMSSSEVGPFVSKIRAVINDI 178
Cdd:pfam00378   6 VAVITLNRPEAVNALSAELITELIQALEKLRTDPSVRAVVLTG-GDKAFCAGADLKEMYGEGPAHQALYRENVLDLWTLL 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275  179 ANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEA 258
Cdd:pfam00378  85 YTCPKPVIAAVNGYAIGGGCELALACDIIIAADNASFGLNETKLGIIPGAGGTDRLPRIIGHSKAMEMLLLGRRISAQEA 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275  259 KAVGLISHVLEQNQegdaAYRKALDLAREFLPQGPVAMRVAK--------------LAINQGM--ETIPTKDRLEGLLAF 322
Cdd:pfam00378 165 LKWGLVDKVVPEDQ----LLDEARELAEKLAEKSPAALAQLKkalnakledalptqLEAEARLfySTFSKDDIIEGLQAF 240

                         250
                  ....*....|
gi 530391275  323 KEKRPPRYKG 332
Cdd:pfam00378 241 LEKRKPPWED 250
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
 99-269 4.10e-17

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 82.19  E-value: 4.10e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275   99 IVVLGINRAYGK-NSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGIFCAGADLKE-RAKMSSSEVGPFVSKIRAVIN 176
Cdd:TIGR02441  23 VAVVKIDSPNSKvNTLSKELFAEFKEVMNELWTNEAIKSAVLISGKPGSFVAGADIQMiAACKTAQEVTQLSQEGQEMFE 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275  177 DIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAK--MGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLD 254
Cdd:TIGR02441 103 RIEKSQKPIVAAISGSCLGGGLELALACHYRIATKDRKtlLGLPEVMLGLLPGAGGTQRLPKLTGVPAALDMMLTGKKIR 182

                         170
                  ....*....|....*
gi 530391275  255 GKEAKAVGLISHVLE 269
Cdd:TIGR02441 183 ADRAKKMGIVDQLVD 197
 
Name Accession Description Interval E-value
PRK07657 PRK07657
enoyl-CoA hydratase; Provisional
 99-333 3.77e-77

enoyl-CoA hydratase; Provisional


Pssm-ID: 181069 [Multi-domain]  Cd Length: 260  Bit Score: 236.94  E-value: 3.77e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275  99 IVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGIFCAGADLKERAKMSSSEVGPFVSKIRAVINDI 178
Cdd:PRK07657  14 VVKITLNRPRAANALSLALLEELQNILTQINEEANVRVVILTGAGEKAFCAGADLKERAGMNEEQVRHAVSLIRTTMEMV 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 179 ANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEA 258
Cdd:PRK07657  94 EQLPQPVIAAINGIALGGGLELALACDFRIAAESASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISAQEA 173

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 259 KAVGLISHVLEQNQEGDaayrKALDLAREFLPQGPVAMRVAKLAINQGME----------------TIPTKDRLEGLLAF 322
Cdd:PRK07657 174 KEIGLVEFVVPAHLLEE----KAIEIAEKIASNGPIAVRQAKEAISNGIQvdlhtglqiekqayegTIPTKDRLEGLQAF 249

                        250
                 ....*....|.
gi 530391275 323 KEKRPPRYKGE 333
Cdd:PRK07657 250 KEKRKPMYKGE 260
PLN02600 PLN02600
enoyl-CoA hydratase
 99-333 2.12e-76

enoyl-CoA hydratase


Pssm-ID: 178210 [Multi-domain]  Cd Length: 251  Bit Score: 234.70  E-value: 2.12e-76
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275  99 IVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGIFCAGADLKERAKMSSSEVGPFVSKIRAVINDI 178
Cdd:PLN02600   5 IVELRLDRPEAKNAIGKEMLRGLRSAFEKIQADASARVVMLRSSVPGVFCAGADLKERRKMSPSEVQKFVNSLRSTFSSL 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 179 ANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEA 258
Cdd:PLN02600  85 EALSIPTIAVVEGAALGGGLELALSCDLRICGEEAVFGLPETGLAIIPGAGGTQRLPRLVGRSRAKELIFTGRRIGAREA 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 259 KAVGLISHVLeqnQEGDaAYRKALDLAREFLPQGPVAMRVAKLAINQGMET----------------IPTKDRLEGLLAF 322
Cdd:PLN02600 165 ASMGLVNYCV---PAGE-AYEKALELAQEINQKGPLAIKMAKKAINEGSEVdmasgleieeecyeqvLKTKDRLEGLAAF 240

                        250
                 ....*....|.
gi 530391275 323 KEKRPPRYKGE 333
Cdd:PLN02600 241 AEKRKPVYTGK 251
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
 98-327 1.54e-54

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 178.44  E-value: 1.54e-54
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275  98 RIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEvPGIFCAGADLKE-RAKMSSSEVGPFVSKIRAVIN 176
Cdd:COG1024    8 GVATITLNRPEKLNALSLEMLAELAAALDEAEADPDVRVVVLTGA-GKAFCAGADLKElAAAADPEEARAFARGLQRLFR 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 177 DIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGK 256
Cdd:COG1024   87 ALRRLPKPVIAAVNGAALGGGLELALACDLRIAAEDARFGLPEVRLGLIPGGGGTQRLPRLVGLARAKELLLTGRRIDAE 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 257 EAKAVGLISHVLEQnqegDAAYRKALDLAREFLPQGPVAMRVAKLAINQGMET----------------IPTKDRLEGLL 320
Cdd:COG1024  167 EALELGLVNRVVPD----DELLAAALALAARLAAGPPLALAATKRALNAALEApldealeleaeafaelFASEDAREGIA 242


                 ....*..
gi 530391275 321 AFKEKRP 327
Cdd:COG1024  243 AFLEKRK 249
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
 98-287 1.59e-46

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 156.18  E-value: 1.59e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275  98 RIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEvPGIFCAGADLKERAKMSSS--EVGPFVSKIRAVI 175
Cdd:cd06558    8 GVATITLNRPEKRNALSLEMLDELAAALDEAEADPDVRVVVLTGA-GKAFCAGADLKELAALSDAgeEARAFIRELQELL 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 176 NDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDG 255
Cdd:cd06558   87 RALLRLPKPVIAAVNGAALGGGLELALACDIRIAAEDAKFGLPEVKLGLVPGGGGTQRLPRLVGPARARELLLTGRRISA 166

                        170       180       190
                 ....*....|....*....|....*....|..
gi 530391275 256 KEAKAVGLISHVLEQnqegDAAYRKALDLARE 287
Cdd:cd06558  167 EEALELGLVDEVVPD----EELLAAALELARR 194
PRK05809 PRK05809
short-chain-enoyl-CoA hydratase;
99-332 1.24e-44

short-chain-enoyl-CoA hydratase;


Pssm-ID: 180270 [Multi-domain]  Cd Length: 260  Bit Score: 153.36  E-value: 1.24e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275  99 IVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGIFCAGADLKERAKMSSSEVGPFVSKIRAVINDI 178
Cdd:PRK05809  14 IAVVTINRPKALNALNSETLKELDTVLDDIENDDNVYAVILTGAGEKAFVAGADISEMKDLNEEEGRKFGLLGNKVFRKL 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 179 ANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEA 258
Cdd:PRK05809  94 ENLDKPVIAAINGFALGGGCELSMACDIRIASEKAKFGQPEVGLGITPGFGGTQRLARIVGPGKAKELIYTGDMINAEEA 173

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 259 KAVGLISHVLEQNQEGDAAYRkaldLAREFLPQGPVAMRVAKLAINQGMET----------------IPTKDRLEGLLAF 322
Cdd:PRK05809 174 LRIGLVNKVVEPEKLMEEAKA----LANKIAANAPIAVKLCKDAINRGMQVdidtavaieaedfgecFSTEDQTEGMTAF 249

                        250
                 ....*....|
gi 530391275 323 KEKRPPRYKG 332
Cdd:PRK05809 250 VEKREKNFKN 259
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
 99-332 1.88e-40

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 142.11  E-value: 1.88e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275   99 IVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSeVPGIFCAGADLKERAKMSSSEVGPFVSKIRAVINDI 178
Cdd:pfam00378   6 VAVITLNRPEAVNALSAELITELIQALEKLRTDPSVRAVVLTG-GDKAFCAGADLKEMYGEGPAHQALYRENVLDLWTLL 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275  179 ANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEA 258
Cdd:pfam00378  85 YTCPKPVIAAVNGYAIGGGCELALACDIIIAADNASFGLNETKLGIIPGAGGTDRLPRIIGHSKAMEMLLLGRRISAQEA 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275  259 KAVGLISHVLEQNQegdaAYRKALDLAREFLPQGPVAMRVAK--------------LAINQGM--ETIPTKDRLEGLLAF 322
Cdd:pfam00378 165 LKWGLVDKVVPEDQ----LLDEARELAEKLAEKSPAALAQLKkalnakledalptqLEAEARLfySTFSKDDIIEGLQAF 240

                         250
                  ....*....|
gi 530391275  323 KEKRPPRYKG 332
Cdd:pfam00378 241 LEKRKPPWED 250
PRK06688 PRK06688
enoyl-CoA hydratase; Provisional
 98-332 3.62e-40

enoyl-CoA hydratase; Provisional


Pssm-ID: 235852 [Multi-domain]  Cd Length: 259  Bit Score: 141.54  E-value: 3.62e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275  98 RIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSeVPGIFCAGADLKERAKmSSSEVGPFVSKIRAVIND 177
Cdd:PRK06688  14 GVLTITINRPDKKNALTAAMYQALADALEAAATDPAVRVVVLTG-AGRAFSAGGDIKDFPK-APPKPPDELAPVNRFLRA 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 178 IANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKE 257
Cdd:PRK06688  92 IAALPKPVVAAVNGPAVGVGVSLALACDLVYASESAKFSLPFAKLGLCPDAGGSALLPRLIGRARAAEMLLLGEPLSAEE 171

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 258 AKAVGLISHVLEQNqEGDAayrKALDLAREfLPQGP-VAMRVAKLAINQGMET----------------IPTKDRLEGLL 320
Cdd:PRK06688 172 ALRIGLVNRVVPAA-ELDA---EADAQAAK-LAAGPaSALRYTKRAINAATLTeleealareaagfgrlLRTPDFREGAT 246

                        250
                 ....*....|..
gi 530391275 321 AFKEKRPPRYKG 332
Cdd:PRK06688 247 AFIEKRKPDFTG 258
PRK07658 PRK07658
enoyl-CoA hydratase; Provisional
 98-333 1.58e-39

enoyl-CoA hydratase; Provisional


Pssm-ID: 181070 [Multi-domain]  Cd Length: 257  Bit Score: 139.77  E-value: 1.58e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275  98 RIVVLGINRAYGkNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEvpG-IFCAGADLKE-RAKMSSSEVGPFVSKIRAVI 175
Cdd:PRK07658  11 HVAVITLNHPPA-NALSSQVLHELSELLDQVEKDDNVRVVVIHGE--GrFFSAGADIKEfTSVTEAEQATELAQLGQVTF 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 176 NDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDG 255
Cdd:PRK07658  88 ERVEKFSKPVIAAIHGAALGGGLELAMSCHIRFATESAKLGLPELNLGLIPGFAGTQRLPRYVGKAKALEMMLTSEPITG 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 256 KEAKAVGLISHVLEQNQegdaAYRKALDLAREFLPQGPVAMRVA--------KLAINQGM--------ETIPTKDRLEGL 319
Cdd:PRK07658 168 AEALKWGLVNGVFPEET----LLDDAKKLAKKIAGKSPATTRAVlellqttkSSSYYEGVkreakifgEVFTSEDAKEGV 243

                        250
                 ....*....|....
gi 530391275 320 LAFKEKRPPRYKGE 333
Cdd:PRK07658 244 QAFLEKRKPSFSGK 257
PRK09674 PRK09674
enoyl-CoA hydratase-isomerase; Provisional
 94-332 6.85e-38

enoyl-CoA hydratase-isomerase; Provisional


Pssm-ID: 182026 [Multi-domain]  Cd Length: 255  Bit Score: 135.66  E-value: 6.85e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275  94 ADHYRIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEvPGIFCAGADLKERAKMSssevgpfvskIRA 173
Cdd:PRK09674   7 SRQQRVLLLTLNRPEARNALNNALLTQLVNELEAAATDTSIGVCVITGN-ARFFAAGADLNEMAEKD----------LAA 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 174 VIND--------IANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKE 245
Cdd:PRK09674  76 TLNDprpqlwqrLQAFNKPLIAAVNGYALGAGCELALLCDIVIAGENARFGLPEITLGIMPGAGGTQRLIRSVGKSLASQ 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 246 LIFSARVLDGKEAKAVGLISHVLEQnqegDAAYRKALDLAREFLPQGPVAMRVAKLAINQGMET---------------- 309
Cdd:PRK09674 156 MVLTGESITAQQAQQAGLVSEVFPP----ELTLERALQLASKIARHSPLALRAAKQALRQSQEVdlqaglaqerqlftll 231

                        250       260
                 ....*....|....*....|...
gi 530391275 310 IPTKDRLEGLLAFKEKRPPRYKG 332
Cdd:PRK09674 232 AATEDRHEGISAFLEKRTPDFKG 254
PRK09245 PRK09245
crotonase/enoyl-CoA hydratase family protein;
99-333 2.75e-34

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181723  Cd Length: 266  Bit Score: 126.24  E-value: 2.75e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275  99 IVVLGINRAYGKNSLSKN-LIKMLSKAVDALKSDKKVRTIIIRSEVPgIFCAGADLKE-RAKMSSSEVGPFVSK------ 170
Cdd:PRK09245  13 IVTLTMNRPETRNALSDNdAVDALVAACAAINADRSVRAVILTGAGT-AFSSGGNVKDmRARVGAFGGSPADIRqgyrhg 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 171 IRAVINDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSA 250
Cdd:PRK09245  92 IQRIPLALYNLEVPVIAAVNGPAIGAGCDLACMCDIRIASETARFAESFVKLGLIPGDGGAWLLPRIIGMARAAEMAFTG 171

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 251 RVLDGKEAKAVGLISHVLEQNQEGDAayrkALDLAREFLPQGPVAMRVAKLAINQGMETI----------------PTKD 314
Cdd:PRK09245 172 DAIDAATALEWGLVSRVVPADQLLPA----ARALAERIAANPPHALRLTKRLLREGQHASldtllelsaayqalahHTAD 247

                        250
                 ....*....|....*....
gi 530391275 315 RLEGLLAFKEKRPPRYKGE 333
Cdd:PRK09245 248 HREAVDAFLEKRPPVFTGR 266
PRK08138 PRK08138
enoyl-CoA hydratase; Provisional
 99-333 4.47e-34

enoyl-CoA hydratase; Provisional


Pssm-ID: 236162 [Multi-domain]  Cd Length: 261  Bit Score: 125.55  E-value: 4.47e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275  99 IVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEvPGIFCAGADLKERAKMSSSEVgpFVSKIRAVINDI 178
Cdd:PRK08138  18 VALLRLNRPEARNALNMEVRQQLAEHFTELSEDPDIRAIVLTGG-EKVFAAGADIKEFATAGAIEM--YLRHTERYWEAI 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 179 ANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEA 258
Cdd:PRK08138  95 AQCPKPVIAAVNGYALGGGCELAMHADIIVAGESASFGQPEIKVGLMPGAGGTQRLVRAVGKFKAMRMALTGCMVPAPEA 174

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 259 KAVGLISHVLEQNQegdaAYRKALDLAREFLPQGPVAMRVAKLAINQGMET----------------IPTKDRLEGLLAF 322
Cdd:PRK08138 175 LAIGLVSEVVEDEQ----TLPRALELAREIARMPPLALAQIKEVVLAGADApldaalalerkafqllFDSEDQKEGMDAF 250

                        250
                 ....*....|.
gi 530391275 323 KEKRPPRYKGE 333
Cdd:PRK08138 251 LEKRKPAYKGK 261
PRK05862 PRK05862
enoyl-CoA hydratase; Provisional
 98-331 1.11e-33

enoyl-CoA hydratase; Provisional


Pssm-ID: 180295 [Multi-domain]  Cd Length: 257  Bit Score: 124.38  E-value: 1.11e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275  98 RIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIR-SEvpGIFCAGADLKERAKMSSSEVgpFVSKIRAVIN 176
Cdd:PRK05862  13 RVGLITLNRPKALNALNDALMDELGAALAAFDADEGIGAIVITgSE--KAFAAGADIKEMADLSFMDV--YKGDYITNWE 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 177 DIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGK 256
Cdd:PRK05862  89 KVARIRKPVIAAVAGYALGGGCELAMMCDIIIAADTAKFGQPEIKLGVLPGMGGSQRLTRAVGKAKAMDLCLTGRMMDAA 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 257 EAKAVGLISHVLEQNQEGDAAYRKALDLAREFLPqgpvAMRVAKLAINQGMET----------------IPTKDRLEGLL 320
Cdd:PRK05862 169 EAERAGLVSRVVPADKLLDEALAAATTIASFSLP----AVMMAKEAVNRAYETtlaegllferrlfhslFATEDQKEGMA 244

                        250
                 ....*....|.
gi 530391275 321 AFKEKRPPRYK 331
Cdd:PRK05862 245 AFVEKRKPVFK 255
PRK07799 PRK07799
crotonase/enoyl-CoA hydratase family protein;
99-333 2.32e-33

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181122 [Multi-domain]  Cd Length: 263  Bit Score: 124.06  E-value: 2.32e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275  99 IVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIrSEVPGIFCAGADLKERAKMSSSEV---GPF-VSKIRAV 174
Cdd:PRK07799  15 TLIVTMNRPEARNALSTEMLRIMVDAWDRVDNDPDIRSCIL-TGAGGAFCAGMDLKAATKKPPGDSfkdGSYdPSRIDAL 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 175 INDiANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLD 254
Cdd:PRK07799  94 LKG-RRLTKPLIAAVEGPAIAGGTEILQGTDIRVAGESAKFGISEAKWSLFPMGGSAVRLVRQIPYTVACDLLLTGRHIT 172

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 255 GKEAKAVGLISHVLEQNQegdaAYRKALDLAREFLPQGPVAMRVAKLAINQ----------------GMETIPTKDRLEG 318
Cdd:PRK07799 173 AAEAKEIGLIGHVVPDGQ----ALDKALELAELINANGPLAVQAILRTIREtegmheneafkidtkiGIPVFLSEDAKEG 248

                        250
                 ....*....|....*
gi 530391275 319 LLAFKEKRPPRYKGE 333
Cdd:PRK07799 249 PRAFAEKRAPNFQGR 263
PRK07509 PRK07509
crotonase/enoyl-CoA hydratase family protein;
104-331 5.65e-31

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181008 [Multi-domain]  Cd Length: 262  Bit Score: 117.29  E-value: 5.65e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 104 INRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEvPGIFCAGADLKERAKMSSSEVGpfvsKIRAVINDIAN--- 180
Cdd:PRK07509  18 LNRPDKMNALDFAMFEELIATIKRLKKDRGIRAVILSGE-GGAFCAGLDVKSVASSPGNAVK----LLFKRLPGNANlaq 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 181 --------LPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARV 252
Cdd:PRK07509  93 rvslgwrrLPVPVIAALEGVCFGGGLQIALGADIRIAAPDTKLSIMEAKWGLVPDMAGTVSLRGLVRKDVARELTYTARV 172

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 253 LDGKEAKAVGLISHVLEQnqegdaAYRKALDLAREFLPQGPVAMRVAKLAINQgMETIP-----------------TKDR 315
Cdd:PRK07509 173 FSAEEALELGLVTHVSDD------PLAAALALAREIAQRSPDAIAAAKRLINR-SWTASvrallaresveqirlllGKNQ 245

                        250
                 ....*....|....*.
gi 530391275 316 LEGLLAFKEKRPPRYK 331
Cdd:PRK07509 246 KIAVKAQMKKRAPKFL 261
fadB PRK11730
fatty acid oxidation complex subunit alpha FadB;
111-277 1.02e-26

fatty acid oxidation complex subunit alpha FadB;


Pssm-ID: 183293 [Multi-domain]  Cd Length: 715  Bit Score: 110.72  E-value: 1.02e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 111 NSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPgIFCAGADLKERA---KMSSSEVGPFVSKIRAVINDIANLPVPTIA 187
Cdd:PRK11730  29 NKLDRATLASLGEALDALEAQSDLKGLLLTSAKD-AFIVGADITEFLslfAAPEEELSQWLHFANSIFNRLEDLPVPTVA 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 188 AIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEAKAVGLISHV 267
Cdd:PRK11730 108 AINGYALGGGCECVLATDYRVASPDARIGLPETKLGIMPGFGGTVRLPRLIGADNALEWIAAGKDVRAEDALKVGAVDAV 187

                        170
                 ....*....|
gi 530391275 268 LEQNQEGDAA 277
Cdd:PRK11730 188 VAPEKLQEAA 197
PRK08252 PRK08252
crotonase/enoyl-CoA hydratase family protein;
98-333 1.78e-26

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181325 [Multi-domain]  Cd Length: 254  Bit Score: 105.07  E-value: 1.78e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275  98 RIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIrSEVPGIFCAGADLKERAKmsssevGPFVSKIRAVIND 177
Cdd:PRK08252  12 RVLIITINRPEARNAVNAAVAQGLAAALDELDADPDLSVGIL-TGAGGTFCAGMDLKAFAR------GERPSIPGRGFGG 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 178 IANLPV--PTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDG 255
Cdd:PRK08252  85 LTERPPrkPLIAAVEGYALAGGFELALACDLIVAARDAKFGLPEVKRGLVAAGGGLLRLPRRIPYHIAMELALTGDMLTA 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 256 KEAKAVGLISHVLEQNQEGDAayrkALDLAREFLPQGPVAMRVAKLAI-------------NQGMETIP---TKDRLEGL 319
Cdd:PRK08252 165 ERAHELGLVNRLTEPGQALDA----ALELAERIAANGPLAVAASKRIVvesgdwsedemfaRQRELIAPvftSADAKEGA 240

                        250
                 ....*....|....
gi 530391275 320 LAFKEKRPPRYKGE 333
Cdd:PRK08252 241 TAFAEKRAPVWTGK 254
PRK06127 PRK06127
enoyl-CoA hydratase; Provisional
 98-332 3.28e-26

enoyl-CoA hydratase; Provisional


Pssm-ID: 235705  Cd Length: 269  Bit Score: 104.79  E-value: 3.28e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275  98 RIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGIFCAGADLKERAKMSSSE--VGPFVSKIRAVI 175
Cdd:PRK06127  20 GLGRITFNNPARHNAMSLDMWEALPQALAAAEDDDAIRVVVLTGAGEKAFVSGADISQFEESRSDAeaVAAYEQAVEAAQ 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 176 NDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDG 255
Cdd:PRK06127 100 AALADYAKPTIACIRGYCIGGGMGIALACDIRIAAEDSRFGIPAARLGLGYGYDGVKNLVDLVGPSAAKDLFYTARRFDA 179

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 256 KEAKAVGLISHVLEqNQEGDAAyrkALDLAREFLPQGPVAMRVAKLAINQ----------------GMETIPTKDRLEGL 319
Cdd:PRK06127 180 AEALRIGLVHRVTA-ADDLETA---LADYAATIAGNAPLTLRAAKRAIAEllkdeperdmaacqalVAACFDSEDYREGR 255

                        250
                 ....*....|...
gi 530391275 320 LAFKEKRPPRYKG 332
Cdd:PRK06127 256 AAFMEKRKPVFKG 268
PRK06494 PRK06494
enoyl-CoA hydratase; Provisional
 98-332 4.26e-26

enoyl-CoA hydratase; Provisional


Pssm-ID: 180591 [Multi-domain]  Cd Length: 259  Bit Score: 104.35  E-value: 4.26e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275  98 RIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGIFCAGADLKERAKMSSSEVGP--FVSkiravI 175
Cdd:PRK06494  13 HVTIVTLNRPEVMNALHLDAHFELEEVFDDFAADPEQWVAIVTGAGDKAFSAGNDLKEQAAGGKRGWPEsgFGG-----L 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 176 NDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDG 255
Cdd:PRK06494  88 TSRFDLDKPIIAAVNGVAMGGGFELALACDLIVAAENATFALPEPRVGLAALAGGLHRLPRQIGLKRAMGMILTGRRVTA 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 256 KEAKAVGLISHVLEQnQEGDAAyrkALDLAREFLPQGPVAMRVAKLAINQGMET------------------IPTKDRLE 317
Cdd:PRK06494 168 REGLELGFVNEVVPA-GELLAA---AERWADDILACSPLSIRASKQAVYRGLEVsleeaitaqrdypavearRASQDYIE 243

                        250
                 ....*....|....*
gi 530391275 318 GLLAFKEKRPPRYKG 332
Cdd:PRK06494 244 GPKAFAEKRPPRWKG 258
PRK11423 PRK11423
methylmalonyl-CoA decarboxylase; Provisional
 98-333 5.28e-26

methylmalonyl-CoA decarboxylase; Provisional


Pssm-ID: 236908 [Multi-domain]  Cd Length: 261  Bit Score: 104.34  E-value: 5.28e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275  98 RIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKkVRTIIIRSEVPG-IFCAGADLKE-----RAKMSSSEvgPFVSKI 171
Cdd:PRK11423  13 KIATITFNNPAKRNALSKVLIDDLMQALSDLNRPE-IRVVILRAPSGSkVWSAGHDIHElpsggRDPLSYDD--PLRQIL 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 172 RAvindIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSAR 251
Cdd:PRK11423  90 RM----IQKFPKPVIAMVEGSVWGGAFELIMSCDLIIAASTSTFAMTPANLGVPYNLSGILNFTNDAGFHIVKEMFFTAS 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 252 VLDGKEAKAVGLISHVLEQNQEGDAAYrkalDLAREFLPQGPVAMRVAK--LAINQGMETIP----------------TK 313
Cdd:PRK11423 166 PITAQRALAVGILNHVVEVEELEDFTL----QMAHHISEKAPLAIAVIKeqLRVLGEAHPMNpdeferiqglrravydSE 241

                        250       260
                 ....*....|....*....|
gi 530391275 314 DRLEGLLAFKEKRPPRYKGE 333
Cdd:PRK11423 242 DYQEGMNAFLEKRKPVFVGH 261
PRK09076 PRK09076
enoyl-CoA hydratase; Provisional
 121-331 3.18e-25

enoyl-CoA hydratase; Provisional


Pssm-ID: 236373 [Multi-domain]  Cd Length: 258  Bit Score: 101.92  E-value: 3.18e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 121 LSKAVDALKSDKKVRTIIIRSEVPGIFCAGADLKErakmsssevgpFVSKIRAVINDIA-----------NLPVPTIAAI 189
Cdd:PRK09076  34 LKQLVLELNADKDVYALVITGDGEKFFSAGADLNL-----------FADGDKAVAREMArrfgeafealsAFRGVSIAAI 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 190 DGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEAKAVGLISHVLE 269
Cdd:PRK09076 103 NGYAMGGGLECALACDIRIAEEQAQMALPEASVGLLPCAGGTQNLPWLVGEGWAKRMILCGERVDAATALRIGLVEEVVE 182

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 530391275 270 QNQEGDAayrkALDLAREFLPQGPVAMRVAKLAINQGMETIP----------------TKDRLEGLLAFKEKRPPRYK 331
Cdd:PRK09076 183 KGEAREA----ALALAQKVANQSPSAVAACKTLIQAARNGPRaaalalerelfvdlfdTEDQREGVNAFLEKRAPQWK 256
PRK05980 PRK05980
crotonase/enoyl-CoA hydratase family protein;
98-330 8.92e-25

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180335 [Multi-domain]  Cd Length: 260  Bit Score: 100.99  E-value: 8.92e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275  98 RIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGIFCAGADLKE----RAKMSSSEVGPFVSKIRA 173
Cdd:PRK05980  12 GIALLTLNRPEKLNALNYALIDRLLARLDAIEVDESVRAVILTGAGDRAFSAGADIHEfsasVAAGADVALRDFVRRGQA 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 174 VINDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVL 253
Cdd:PRK05980  92 MTARLEAFPKPVIAAVNGLAFGGGCEITEAVHLAIASERALFAKPEIRLGMPPTFGGTQRLPRLAGRKRALELLLTGDAF 171

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 254 DGKEAKAVGLISHVLEQnqegDAAYRKALDLAREFLPQGPVAM--------RVAKLAINQGMET--------IPTKDRLE 317
Cdd:PRK05980 172 SAERALEIGLVNAVVPH----EELLPAARALARRIIRHSPVAVaailtavtRGLNLSIAEGLLIeseqfarmAGSADLRE 247

                        250
                 ....*....|...
gi 530391275 318 GLLAFKEKRPPRY 330
Cdd:PRK05980 248 GLAAWIERRRPAY 260
PRK06210 PRK06210
enoyl-CoA hydratase; Provisional
 94-332 4.13e-24

enoyl-CoA hydratase; Provisional


Pssm-ID: 180472  Cd Length: 272  Bit Score: 99.39  E-value: 4.13e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275  94 ADHYRIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGiFCAGADLKE------RAKMSSSEVGPF 167
Cdd:PRK06210  11 VADSGVAVITLNRPDRLNAWTPVMEAEVYAAMDRAEADPAVRVIVLTGAGRG-FCAGADMGElqtidpSDGRRDTDVRPF 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 168 VSKIRAVIND----IANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLA 243
Cdd:PRK06210  90 VGNRRPDYQTryhfLTALRKPVIAAINGACAGIGLTHALMCDVRFAADGAKFTTAFARRGLIAEHGISWILPRLVGHANA 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 244 KELIFSARVLDGKEAKAVGLISHVLEQNQEGDAAYRKALDLAREFlpqGPVAMRVAKLAI---------------NQGM- 307
Cdd:PRK06210 170 LDLLLSARTFYAEEALRLGLVNRVVPPDELMERTLAYAEDLARNV---SPASMAVIKRQLyedafqtlaeataraNREMh 246

                        250       260
                 ....*....|....*....|....*
gi 530391275 308 ETIPTKDRLEGLLAFKEKRPPRYKG 332
Cdd:PRK06210 247 ESLQRPDFIEGVASFLEKRPPRFPG 271
PRK07468 PRK07468
crotonase/enoyl-CoA hydratase family protein;
88-332 9.17e-24

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180987 [Multi-domain]  Cd Length: 262  Bit Score: 98.21  E-value: 9.17e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275  88 DSSSMAADHYRIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGiFCAGADLK-ERAKMSSSEVGP 166
Cdd:PRK07468   4 ETIRIAVDARGVATLTLNRPEKHNALSARMIAELTTAARRLAADAAVRVVVLTGAGKS-FCAGGDLGwMRAQMTADRATR 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 167 FVS--KIRAVINDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRaIGMSLAK 244
Cdd:PRK07468  83 IEEarRLAMMLKALNDLPKPLIGRIQGQAFGGGVGLISVCDVAIAVSGARFGLTETRLGLIPATISPYVVAR-MGEANAR 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 245 ELIFSARVLDGKEAKAVGLISHVLEQnQEGDAAYRKALdlaREFLPQGPVAMRVAK-LA---------------INQGME 308
Cdd:PRK07468 162 RVFMSARLFDAEEAVRLGLLSRVVPA-ERLDAAVEAEV---TPYLSCAPGAVAAAKaLVralgapideavidatIEALAD 237

                        250       260
                 ....*....|....*....|....
gi 530391275 309 TIPTKDRLEGLLAFKEKRPPRYKG 332
Cdd:PRK07468 238 TWETEEAREGIAAFFDKRAPAWRG 261
PRK06190 PRK06190
enoyl-CoA hydratase; Provisional
 94-309 5.02e-23

enoyl-CoA hydratase; Provisional


Pssm-ID: 235733  Cd Length: 258  Bit Score: 95.81  E-value: 5.02e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275  94 ADHYRIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPgIFCAGADLKERAKMSSSEVGPFVSK--I 171
Cdd:PRK06190   9 ETHDRVRTLTLNRPEARNALSAALRRALFAALAEADADDDVDVVVLTGADP-AFCAGLDLKELGGDGSAYGAQDALPnpS 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 172 RAVindiANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSAR 251
Cdd:PRK06190  88 PAW----PAMRKPVIGAINGAAVTGGLELALACDILIASERARFADTHARVGILPGWGLSVRLPQKVGIGRARRMSLTGD 163

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 530391275 252 VLDGKEAKAVGLISHVLEQNQEGDAayrkALDLAREFLPQGPVAMRVAKLAINQGMET 309
Cdd:PRK06190 164 FLDAADALRAGLVTEVVPHDELLPR----ARRLAASIAGNNPAAVRALKASYDDGAAA 217
PRK05869 PRK05869
enoyl-CoA hydratase; Validated
 111-304 6.01e-23

enoyl-CoA hydratase; Validated


Pssm-ID: 235632 [Multi-domain]  Cd Length: 222  Bit Score: 94.91  E-value: 6.01e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 111 NSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEvPGIFCAGADLKERAKMSSSEVGPFVSKIRAVINDIANLPVPTIAAID 190
Cdd:PRK05869  29 NALTRQVYREIVAAANELGRRDDVAAVILYGG-HEIFSAGDDMPELRTLSAQEADTAARVRQQAVDAVAAIPKPTVAAIT 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 191 GLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEAKAVGLISHVLEQ 270
Cdd:PRK05869 108 GYALGAGLTLALAADWRVSGDNVKFGATEILAGLAPSGDGMARLTRAAGPSRAKELVFSGRFFDAEEALALGLIDEMVAP 187

                        170       180       190
                 ....*....|....*....|....*....|....
gi 530391275 271 nqegDAAYRKALDLAREFLPQGPVAMRVAKLAIN 304
Cdd:PRK05869 188 ----DDVYDAAAAWARRFLDGPPHALAAAKAGIS 217
PRK05995 PRK05995
enoyl-CoA hydratase; Provisional
 104-333 6.59e-23

enoyl-CoA hydratase; Provisional


Pssm-ID: 235664 [Multi-domain]  Cd Length: 262  Bit Score: 95.76  E-value: 6.59e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 104 INRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGiFCAGADL---KERAKMSSSEVGPFVSKIRAVINDIAN 180
Cdd:PRK05995  19 LNRPDVRNAFNETVIAELTAAFRALDADDSVRAVVLAGAGKA-FCAGADLnwmKKMAGYSDDENRADARRLADMLRAIYR 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 181 LPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPggggTQRLP---RAIGMSLAKELIFSARVLDGKE 257
Cdd:PRK05995  98 CPKPVIARVHGDAYAGGMGLVAACDIAVAADHAVFCLSEVRLGLIP----ATISPyviRAMGERAARRYFLTAERFDAAE 173

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 258 AKAVGLISHVLEQnQEGDAayrKALDLAREFLPQGPVAMRVAKLAInQGMETIPTKDRL------------------EGL 319
Cdd:PRK05995 174 ALRLGLVHEVVPA-EALDA---KVDELLAALVANSPQAVRAGKRLV-RDVAGRPIDAALiadtasrialirateearEGV 248

                        250
                 ....*....|....
gi 530391275 320 LAFKEKRPPRYKGE 333
Cdd:PRK05995 249 AAFLEKRKPAWRGR 262
PRK06144 PRK06144
enoyl-CoA hydratase; Provisional
 105-332 7.10e-23

enoyl-CoA hydratase; Provisional


Pssm-ID: 180424 [Multi-domain]  Cd Length: 262  Bit Score: 95.83  E-value: 7.10e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 105 NRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGIFCAGADLKERAKMSSSEVG-PFVSKIRAVINDIANLPV 183
Cdd:PRK06144  24 NRPAARNAMTWAMYEGLAEICEAIAADPSIRAVVLRGAGDKAFVAGTDIAQFRAFSTAEDAvAYERRIDRVLGALEQLRV 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 184 PTIAAIDGLALGGGLELALACDIRVAASSAKMG----------LVETKLAiipggggtqRLPRAIGMSLAKELIFSARVL 253
Cdd:PRK06144 104 PTIAAIAGACVGGGAAIAAACDLRIATPSARFGfpiartlgncLSMSNLA---------RLVALLGAARVKDMLFTARLL 174

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 254 DGKEAKAVGLISHVLEQnqegDAAYRKALDLAREFLPQGPVAMRVAKLAIN-QGMETIPTKDRL-----------EGLLA 321
Cdd:PRK06144 175 EAEEALAAGLVNEVVED----AALDARADALAELLAAHAPLTLRATKEALRrLRREGLPDGDDLirmcymsedfrEGVEA 250

                        250
                 ....*....|.
gi 530391275 322 FKEKRPPRYKG 332
Cdd:PRK06144 251 FLEKRPPKWKG 261
PRK08150 PRK08150
crotonase/enoyl-CoA hydratase family protein;
98-286 7.78e-23

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181254  Cd Length: 255  Bit Score: 95.47  E-value: 7.78e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275  98 RIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDkkVRTIIIRSEVPGiFCAGADLKERAKMSSSEVGPFVSKIRAVIND 177
Cdd:PRK08150  11 GVATIGLNRPAKRNALNDGLIAALRAAFARLPEG--VRAVVLHGEGDH-FCAGLDLSELRERDAGEGMHHSRRWHRVFDK 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 178 IANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKE 257
Cdd:PRK08150  88 IQYGRVPVIAALHGAVVGGGLELASAAHIRVADESTYFALPEGQRGIFVGGGGSVRVPRLIGVARMTDMMLTGRVYDAQE 167

                        170       180
                 ....*....|....*....|....*....
gi 530391275 258 AKAVGLISHVLEQNQegdaAYRKALDLAR 286
Cdd:PRK08150 168 GERLGLAQYLVPAGE----ALDKAMELAR 192
PRK08260 PRK08260
enoyl-CoA hydratase; Provisional
 99-332 1.28e-21

enoyl-CoA hydratase; Provisional


Pssm-ID: 236206 [Multi-domain]  Cd Length: 296  Bit Score: 92.76  E-value: 1.28e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275  99 IVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIirseVPG---IFCAGADL---------KERAKMSSS---- 162
Cdd:PRK08260  14 IATITLNRPDKLNAFTVTMARELIEAFDAADADDAVRAVI----VTGagrAFCAGADLsaggntfdlDAPRTPVEAdeed 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 163 EVGPFVSKIR----AVINDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAI 238
Cdd:PRK08260  90 RADPSDDGVRdgggRVTLRIFDSLKPVIAAVNGPAVGVGATMTLAMDIRLASTAARFGFVFGRRGIVPEAASSWFLPRLV 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 239 GMSLAKELIFSARVLDGKEAKAVGLISHVLEQNQEGDAAYrkalDLAREFLPQ-GPV--------------------AMR 297
Cdd:PRK08260 170 GLQTALEWVYSGRVFDAQEALDGGLVRSVHPPDELLPAAR----ALAREIADNtSPVsvaltrqmmwrmagadhpmeAHR 245

                        250       260       270
                 ....*....|....*....|....*....|....*
gi 530391275 298 VAKLAINqgmETIPTKDRLEGLLAFKEKRPPRYKG 332
Cdd:PRK08260 246 VDSRAIY---SRGRSGDGKEGVSSFLEKRPAVFPG 277
PRK03580 PRK03580
crotonobetainyl-CoA hydratase;
127-333 1.18e-20

crotonobetainyl-CoA hydratase;


Pssm-ID: 179599 [Multi-domain]  Cd Length: 261  Bit Score: 89.37  E-value: 1.18e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 127 ALKSDKKVRTIIIRSEVPGIFCAGADLKERAKMSSSE----VGPFvskirAVINDIANLPVPTIAAIDGLALGGGLELAL 202
Cdd:PRK03580  40 NFRDDPELRVAIITGAGEKFFSAGWDLKAAAEGEAPDadfgPGGF-----AGLTEIFDLDKPVIAAVNGYAFGGGFELAL 114

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 203 ACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEAKAVGLISHVLEQNQEGDAAYrkal 282
Cdd:PRK03580 115 AADFIVCADNASFALPEAKLGIVPDSGGVLRLPKRLPPAIANEMVMTGRRMDAEEALRWGIVNRVVPQAELMDRAR---- 190

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 530391275 283 DLAREFLPQGPVAMRVAK--------LAINQGM--------ETIP----TKDRLEGLLAFKEKRPPRYKGE 333
Cdd:PRK03580 191 ELAQQLVNSAPLAIAALKeiyretseMPVEEAYryirsgvlKHYPsvlhSEDALEGPRAFAEKRDPVWKGR 261
PRK06143 PRK06143
enoyl-CoA hydratase; Provisional
 99-300 1.79e-20

enoyl-CoA hydratase; Provisional


Pssm-ID: 180423  Cd Length: 256  Bit Score: 88.94  E-value: 1.79e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275  99 IVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGIFCAGADLKERAKMSSSEVGPFVSKIRAVINDI 178
Cdd:PRK06143  17 VATLTIRNAGSLNILGTPVILALTQALRWLAADPDVRVLVLRGAGEKAFIGGADIKEMATLDQASAEAFISRLRDLCDAV 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 179 ANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAiIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEA 258
Cdd:PRK06143  97 RHFPVPVIARIPGWCLGGGLELAAACDLRIAAHDAQFGMPEVRVG-IPSVIHAALLPRLIGWARTRWLLLTGETIDAAQA 175

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 530391275 259 KAVGLISHVLEqNQEGDAAYRKaldLAREFLPQGPVAMRVAK 300
Cdd:PRK06143 176 LAWGLVDRVVP-LAELDAAVER---LAASLAGCGPQALRQQK 213
PRK06563 PRK06563
crotonase/enoyl-CoA hydratase family protein;
99-332 2.02e-20

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180625 [Multi-domain]  Cd Length: 255  Bit Score: 88.86  E-value: 2.02e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275  99 IVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGiFCAGADLKERA--------KMSSSEVGPF--- 167
Cdd:PRK06563   9 VLLIGLDRPAKRNAFDSAMLDDLALALGEYEADDELRVAVLFAHGEH-FTAGLDLADVApklaaggfPFPEGGIDPWgtv 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 168 ---VSKiravindianlpvPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAK 244
Cdd:PRK06563  88 grrLSK-------------PLVVAVQGYCLTLGIELMLAADIVVAADNTRFAQLEVQRGILPFGGATLRFPQAAGWGNAM 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 245 ELIFSARVLDGKEAKAVGLISHVLEQNQEgdaaYRKALDLAREFLPQGPVAMRV----AKLAINQG----METIP----- 311
Cdd:PRK06563 155 RYLLTGDEFDAQEALRLGLVQEVVPPGEQ----LERAIELAERIARAAPLGVQAtlasARAAVREGeaaaAAQLPpelrp 230

                        250       260
                 ....*....|....*....|....
gi 530391275 312 ---TKDRLEGLLAFKEKRPPRYKG 332
Cdd:PRK06563 231 lftSEDAKEGVQAFLERRPARFKG 254
fadJ PRK11154
fatty acid oxidation complex subunit alpha FadJ;
128-282 4.72e-20

fatty acid oxidation complex subunit alpha FadJ;


Pssm-ID: 236864 [Multi-domain]  Cd Length: 708  Bit Score: 91.11  E-value: 4.72e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 128 LKSDKKVRTIIIRSEVPGIFCAGADLKERAKMSSSEVGPFVS-KIRAVINDIANLPVPTIAAIDGLALGGGLELALACDI 206
Cdd:PRK11154  46 LREDKELKGVVFISGKPDNFIAGADINMLAACKTAQEAEALArQGQQLFAEIEALPIPVVAAIHGACLGGGLELALACHY 125

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 530391275 207 RVAASSAK--MGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEAKAVGLISHVLEQNQEGDAAYRKAL 282
Cdd:PRK11154 126 RVCTDDPKtvLGLPEVQLGLLPGSGGTQRLPRLIGVSTALDMILTGKQLRAKQALKLGLVDDVVPHSILLEVAVELAK 203
PRK06142 PRK06142
crotonase/enoyl-CoA hydratase family protein;
94-332 6.85e-20

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 235714  Cd Length: 272  Bit Score: 87.72  E-value: 6.85e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275  94 ADHyrIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGiFCAGADLKERA-----KMSSSEVGP-- 166
Cdd:PRK06142  13 ADH--VAQVTLNRPGKGNAMNPAFWSELPEIFRWLDADPEVRAVVLSGSGKH-FSYGIDLPAMAgvfgqLGKDGLARPrt 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 167 -FVSKIR---AVINDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSL 242
Cdd:PRK06142  90 dLRREILrlqAAINAVADCRKPVIAAVQGWCIGGGVDLISACDMRYASADAKFSVREVDLGMVADVGSLQRLPRIIGDGH 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 243 AKELIFSARVLDGKEAKAVGLISHVLEqnqEGDAAYRKALDLAREFLPQGPVAMRVAKLAINQ--------GMETI---- 310
Cdd:PRK06142 170 LRELALTGRDIDAAEAEKIGLVNRVYD---DADALLAAAHATAREIAAKSPLAVRGTKEVLDYmrdhrvadGLRYVatwn 246

                        250       260
                 ....*....|....*....|....*.
gi 530391275 311 ----PTKDRLEGLLAFKEKRPPRYKG 332
Cdd:PRK06142 247 aamlPSKDLTEAIAAHMEKRPPEFTG 272
PLN02888 PLN02888
enoyl-CoA hydratase
 99-307 1.14e-19

enoyl-CoA hydratase


Pssm-ID: 215480  Cd Length: 265  Bit Score: 86.73  E-value: 1.14e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275  99 IVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGiFCAGADLKerakmSSSEVGPFVSKIRAvINDI 178
Cdd:PLN02888  20 IATITINRPKALNALTRPMMVELAAAFKRLDEDDSVKVIILTGSGRA-FCSGVDLT-----AAEEVFKGDVKDVE-TDPV 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 179 ANLP---VPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDG 255
Cdd:PLN02888  93 AQMErcrKPIIGAINGFAITAGFEIALACDILVASRGAKFIDTHAKFGIFPSWGLSQKLSRIIGANRAREVSLTAMPLTA 172

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 530391275 256 KEAKAVGLISHVLEQNQegdaAYRKALDLAREFLPQGPVAMRVAKLAINQGM 307
Cdd:PLN02888 173 ETAERWGLVNHVVEESE----LLKKAREVAEAIIKNNQGMVLRYKSVINDGL 220
PRK07511 PRK07511
enoyl-CoA hydratase; Provisional
 101-332 1.24e-19

enoyl-CoA hydratase; Provisional


Pssm-ID: 181009 [Multi-domain]  Cd Length: 260  Bit Score: 86.59  E-value: 1.24e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 101 VLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEvPGIFCAGADLK---ERAKMSSSEVGPFVSKIRAVIND 177
Cdd:PRK07511  15 VLTLSNPGARNALHPDMYAAGIEALNTAERDPSIRAVVLTGA-GGFFCAGGNLNrllENRAKPPSVQAASIDGLHDWIRA 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 178 IANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKE 257
Cdd:PRK07511  94 IRAFPKPVIAAVEGAAAGAGFSLALACDLLVAARDAKFVMAYVKVGLTPDGGGSWFLARALPRQLATELLLEGKPISAER 173

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 258 AKAVGLISHVLEQNQEGDAayrkALDLAREFLPQGPVAMRVAKLAINQG----------------METIPTKDRLEGLLA 321
Cdd:PRK07511 174 LHALGVVNRLAEPGQALAE----ALALADQLAAGSPNALARIKSLIADApeatlaaqleaerdhfVASLHHADALEGIAA 249

                        250
                 ....*....|.
gi 530391275 322 FKEKRPPRYKG 332
Cdd:PRK07511 250 FLEKRAPDYKR 260
PRK06495 PRK06495
enoyl-CoA hydratase/isomerase family protein;
111-332 1.76e-19

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 168580 [Multi-domain]  Cd Length: 257  Bit Score: 86.29  E-value: 1.76e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 111 NSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEvPGIFCAGADLKERAKMSSSEvGPFVS---KIRAVINDIANLPVPTIA 187
Cdd:PRK06495  25 NALSRELRDELIAVFDEISERPDVRVVVLTGA-GKVFCAGADLKGRPDVIKGP-GDLRAhnrRTRECFHAIRECAKPVIA 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 188 AIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIpggGGTQRLPRAIGMSLAKELIFSARVLDGKEAKAVGLISHV 267
Cdd:PRK06495 103 AVNGPALGAGLGLVASCDIIVASENAVFGLPEIDVGLA---GGGKHAMRLFGHSLTRRMMLTGYRVPAAELYRRGVIEAC 179

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 268 LeqnqEGDAAYRKALDLAREFLPQGPVAMRVAKLAINQgMETIP-----------------TKDRLEGLLAFKEKRPPRY 330
Cdd:PRK06495 180 L----PPEELMPEAMEIAREIASKSPLATRLAKDALNT-IENMSlrdgyryeqditaklakTEDAKEAQRAFLEKRPPVF 254


                 ..
gi 530391275 331 KG 332
Cdd:PRK06495 255 KG 256
PLN02664 PLN02664
enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase
 99-330 2.59e-19

enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase


Pssm-ID: 178269 [Multi-domain]  Cd Length: 275  Bit Score: 86.11  E-value: 2.59e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275  99 IVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVrTIIIRSEVPGIFCAGADLKERAKMS----SSEVGPFVSKIR-- 172
Cdd:PLN02664  18 VFHLNLNRPSQRNALSLDFFTEFPKALSSLDQNPNV-SVIILSGAGDHFCSGIDLKTLNSISeqssSGDRGRSGERLRrk 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 173 -----AVINDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELI 247
Cdd:PLN02664  97 ikflqDAITAIEQCRKPVIAAIHGACIGGGVDIVTACDIRYCSEDAFFSVKEVDLAITADLGTLQRLPSIVGYGNAMELA 176

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 248 FSARVLDGKEAKAVGLISHVLEQNQEGDAAYRKaldLAREFLPQGPVA--------MRVAKLAINQGMETIPT------- 312
Cdd:PLN02664 177 LTGRRFSGSEAKELGLVSRVFGSKEDLDEGVRL---IAEGIAAKSPLAvtgtkavlLRSRELSVEQGLDYVATwnsamlv 253

                        250
                 ....*....|....*....
gi 530391275 313 -KDRLEGLLAFKEKRPPRY 330
Cdd:PLN02664 254 sDDLNEAVSAQIQKRKPVF 272
PRK08139 PRK08139
enoyl-CoA hydratase; Validated
 99-333 2.95e-19

enoyl-CoA hydratase; Validated


Pssm-ID: 181249  Cd Length: 266  Bit Score: 85.76  E-value: 2.95e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275  99 IVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPgIFCAGADLKE-RAKMSSSEVGPFVSKIRAVIND 177
Cdd:PRK08139  21 VATLTLNRPQAFNALSEAMLAALQAALDAIAADPSVRVVVLAAAGK-AFCAGHDLKEmRAARGLAYFRALFARCSRVMQA 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 178 IANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAII---PGGGgtqrLPRAIGMSLAKELIFSARVLD 254
Cdd:PRK08139 100 IVALPQPVIARVHGIATAAGCQLVASCDLAVAADTARFAVPGVNIGLFcstPMVA----LSRNVPRKQAMEMLLTGEFID 175

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 255 GKEAKAVGLISHVLEQNQEGDAAYRkaldLAREFLPQGPVAMRVAKLAINQ--GM--------------ETIPTKDRLEG 318
Cdd:PRK08139 176 AATAREWGLVNRVVPADALDAAVAR----LAAVIAAKSPAAVRIGKEAFYRqaEMpladayayagdvmaENMMAEDAEEG 251

                        250
                 ....*....|....*
gi 530391275 319 LLAFKEKRPPRYKGE 333
Cdd:PRK08139 252 IDAFLEKRPPEWRGR 266
PRK08140 PRK08140
enoyl-CoA hydratase; Provisional
 94-333 5.32e-19

enoyl-CoA hydratase; Provisional


Pssm-ID: 236163  Cd Length: 262  Bit Score: 84.97  E-value: 5.32e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275  94 ADHYRIVVLGINRAYGKNSLSKNLIKMLSKAVDALKsDKKVRTIIIRSEVPGiFCAGADLKERAKMSSSEV--------- 164
Cdd:PRK08140   9 AIEAGVATLTLNRPDKLNSFTREMHRELREALDQVE-DDGARALLLTGAGRG-FCAGQDLADRDVTPGGAMpdlgesiet 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 165 --GPFVSKIRAvindianLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSL 242
Cdd:PRK08140  87 fyNPLVRRLRA-------LPLPVIAAVNGVAAGAGANLALACDIVLAARSASFIQAFVKIGLVPDSGGTWFLPRLVGMAR 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 243 AKELIFSARVLDGKEAKAVGLISHVLEqnqegDAAYR-KALDLAREFLPQGPVAMRVAKLAINQGM-------------- 307
Cdd:PRK08140 160 ALGLALLGEKLSAEQAEQWGLIWRVVD-----DAALAdEAQQLAAHLATQPTRGLALIKQAMNASAtntldaqldlerdl 234

                        250       260
                 ....*....|....*....|....*...
gi 530391275 308 --ETIPTKDRLEGLLAFKEKRPPRYKGE 333
Cdd:PRK08140 235 qrEAGRSADYAEGVSAFLEKRAPRFTGR 262
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
 99-269 4.10e-17

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 82.19  E-value: 4.10e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275   99 IVVLGINRAYGK-NSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGIFCAGADLKE-RAKMSSSEVGPFVSKIRAVIN 176
Cdd:TIGR02441  23 VAVVKIDSPNSKvNTLSKELFAEFKEVMNELWTNEAIKSAVLISGKPGSFVAGADIQMiAACKTAQEVTQLSQEGQEMFE 102

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275  177 DIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAK--MGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLD 254
Cdd:TIGR02441 103 RIEKSQKPIVAAISGSCLGGGLELALACHYRIATKDRKtlLGLPEVMLGLLPGAGGTQRLPKLTGVPAALDMMLTGKKIR 182

                         170
                  ....*....|....*
gi 530391275  255 GKEAKAVGLISHVLE 269
Cdd:TIGR02441 183 ADRAKKMGIVDQLVD 197
PRK05870 PRK05870
enoyl-CoA hydratase; Provisional
 98-269 8.19e-17

enoyl-CoA hydratase; Provisional


Pssm-ID: 180298  Cd Length: 249  Bit Score: 78.61  E-value: 8.19e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275  98 RIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGiFCAGADLKERAKMSSSEVGPFVSKIRAVIND 177
Cdd:PRK05870  12 GVALITVNDPDRRNAVTAEMSAQLRAAVAAAEADPDVHALVVTGAGKA-FCAGADLTALGAAPGRPAEDGLRRIYDGFLA 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 178 IANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKE 257
Cdd:PRK05870  91 VASCPLPTIAAVNGAAVGAGLNLALAADVRIAGPKALFDARFQKLGLHPGGGATWMLQRAVGPQVARAALLFGMRFDAEA 170

                        170
                 ....*....|..
gi 530391275 258 AKAVGLISHVLE 269
Cdd:PRK05870 171 AVRHGLALMVAD 182
PRK07854 PRK07854
enoyl-CoA hydratase; Provisional
 98-332 3.53e-16

enoyl-CoA hydratase; Provisional


Pssm-ID: 236115 [Multi-domain]  Cd Length: 243  Bit Score: 76.60  E-value: 3.53e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275  98 RIVVLGINRAYGKNSLSKNLIKMLSKAVDALkSDKKVRTIIIRSEVPgIFCAGADLKERAKMSSsevgpFVSKIRAVIND 177
Cdd:PRK07854   9 QVLTIELQRPERRNALNAELCEELREAVRKA-VDESARAIVLTGQGT-VFCAGADLSGDVYADD-----FPDALIEMLHA 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 178 IANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKE 257
Cdd:PRK07854  82 IDAAPVPVIAAINGPAIGAGLQLAMACDLRVVAPEAYFQFPVAKYGIALDNWTIRRLSSLVGGGRARAMLLGAEKLTAEQ 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 258 AKAVGLIshvleqNQEGDAAyrKALDLAREFLPQGPVAMRVAKLAINQGMETIP--------------TKDRLEGLLAFK 323
Cdd:PRK07854 162 ALATGMA------NRIGTLA--DAQAWAAEIAGLAPLALQHAKRVLNDDGAIEEawpahkelfdkawaSQDAIEAQVARI 233


                 ....*....
gi 530391275 324 EKRPPRYKG 332
Cdd:PRK07854 234 EKRPPKFQG 242
PRK07827 PRK07827
enoyl-CoA hydratase family protein;
98-330 4.80e-15

enoyl-CoA hydratase family protein;


Pssm-ID: 236109 [Multi-domain]  Cd Length: 260  Bit Score: 73.95  E-value: 4.80e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275  98 RIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIrSEVPGIFCAGADLKERAKMSSSEVGPFVSKIRAVIN- 176
Cdd:PRK07827  15 GVATLTLDSPHNRNALSARLVAQLHDGLRAAAADPAVRAVVL-THTGGTFCAGADLSEAGGGGGDPYDAAVARAREMTAl 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 177 --DIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARvLD 254
Cdd:PRK07827  94 lrAIVELPKPVIAAIDGHVRAGGFGLVGACDIVVAGPESTFALTEARIGVAPAIISLTLLPRLSPRAAARYYLTGEK-FG 172

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 255 GKEAKAVGLIShvlEQNQEGDAAYRKALDLAREFLPQGPVAM-------------RVAKLAINQGMETIPTKDRLEGLLA 321
Cdd:PRK07827 173 AAEAARIGLVT---AAADDVDAAVAALLADLRRGSPQGLAESkalttaavlagfdRDAEELTEESARLFVSDEAREGMTA 249


                 ....*....
gi 530391275 322 FKEKRPPRY 330
Cdd:PRK07827 250 FLQKRPPRW 258
PRK08258 PRK08258
enoyl-CoA hydratase family protein;
98-332 1.24e-14

enoyl-CoA hydratase family protein;


Pssm-ID: 181329  Cd Length: 277  Bit Score: 72.69  E-value: 1.24e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275  98 RIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGiFCAGADLKE----RAKMSSSEVGPFVSKIRA 173
Cdd:PRK08258  26 GVATITLNRPERKNPLTFESYAELRDLFRELVYADDVKAVVLTGAGGN-FCSGGDVHEiigpLTKMDMPELLAFTRMTGD 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 174 VINDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETK--LAiipGG--GGTQRLPRAIGMSLAKELIFS 249
Cdd:PRK08258 105 LVKAMRACPQPIIAAVDGVCAGAGAILAMASDLRLGTPSAKTAFLFTRvgLA---GAdmGACALLPRIIGQGRASELLYT 181

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 250 ARVLDGKEAKAVGLISHVLEQNQEGDAAYRKALDLAReflpqGPV---AMRVAKLA------INQGMET--------IPT 312
Cdd:PRK08258 182 GRSMSAEEGERWGFFNRLVEPEELLAEAQALARRLAA-----GPTfahGMTKTMLHqewdmgLEEAIEAeaqaqaicMQT 256

                        250       260
                 ....*....|....*....|
gi 530391275 313 KDRLEGLLAFKEKRPPRYKG 332
Cdd:PRK08258 257 EDFRRAYEAFVAKRKPVFEG 276
PLN02921 PLN02921
naphthoate synthase
 104-330 1.44e-14

naphthoate synthase


Pssm-ID: 178509 [Multi-domain]  Cd Length: 327  Bit Score: 73.28  E-value: 1.44e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 104 INRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGIFCAGADLKERAKmsSSEVGPFVSKIRAVIN---DIAN 180
Cdd:PLN02921  82 INRPERRNAFRPRTVKELQRAFNDARDDSSVGVIILTGKGTKAFCSGGDQAVRGK--DGYVGPDDAGRLNVLDlqiQIRR 159

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 181 LPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEAKA 260
Cdd:PLN02921 160 LPKPVIAMVAGYAVGGGHILHMVCDLTIAADNAVFGQTGPKVGSFDAGYGSSIMARLVGQKKAREMWFLARFYTASEALK 239

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 261 VGLISHVLEQNQ-EGDAAyrkalDLAREFLPQGPVAMRVAKLAINQ------------GMETI---PTKDRLEGLLAFKE 324
Cdd:PLN02921 240 MGLVNTVVPLDElEGETV-----KWCREILRNSPTAIRVLKSALNAaddghaglqelgGNATLlfyGSEEGNEGRTAYLE 314


                 ....*.
gi 530391275 325 KRPPRY 330
Cdd:PLN02921 315 GRAPDF 320
PRK07659 PRK07659
enoyl-CoA hydratase; Provisional
 98-333 1.73e-14

enoyl-CoA hydratase; Provisional


Pssm-ID: 236073 [Multi-domain]  Cd Length: 260  Bit Score: 72.37  E-value: 1.73e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275  98 RIVVLGINRAYGKNSLSKNLIKMLSKAVDALK-SDKKVrtIIIRSEVPGiFCAGADLKERAKMSSSEVGPFVSK-IRAVI 175
Cdd:PRK07659  15 RVATIMLNRPEALNALDEPMLKELLQALKEVAeSSAHI--VVLRGNGRG-FSAGGDIKMMLSSNDESKFDGVMNtISEIV 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 176 NDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDG 255
Cdd:PRK07659  92 VTLYTMPKLTISAIHGPAAGLGLSIALTADYVIADISAKLAMNFIGIGLIPDGGGHFFLQKRVGENKAKQIIWEGKKLSA 171

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 256 KEAKAVGLISHVLEqnQEGDAAYRKALDlarEFLPQGPVAM----------------RVAKLAINQGMETIPTKDRLEGL 319
Cdd:PRK07659 172 TEALDLGLIDEVIG--GDFQTAAKQKIS---EWLQKPLKAMietkqiycelnrsqleQVLQLEKRAQYAMRQTADHKEGI 246

                        250
                 ....*....|....
gi 530391275 320 LAFKEKRPPRYKGE 333
Cdd:PRK07659 247 RAFLEKRLPVFKGE 260
PRK07327 PRK07327
enoyl-CoA hydratase/isomerase family protein;
98-332 1.23e-13

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 235991  Cd Length: 268  Bit Score: 69.66  E-value: 1.23e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275  98 RIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGiFCAGADLKERAKMSSS-EVGPFVSK-IRAVI 175
Cdd:PRK07327  21 GVLEIVLNGPGALNAADARMHRELADIWRDVDRDPDVRVVLIRGEGKA-FSAGGDLALVEEMADDfEVRARVWReARDLV 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 176 NDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDG 255
Cdd:PRK07327 100 YNVINCDKPIVSAIHGPAVGAGLVAALLADISIAAKDARIIDGHTRLGVAAGDHAAIVWPLLCGMAKAKYYLLLCEPVSG 179

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 256 KEAKAVGLISHVLEQnqegDAAYRKALDLAREfLPQG-PVAMRVAKLAINQGMETI-PT--------------KDRLEGL 319
Cdd:PRK07327 180 EEAERIGLVSLAVDD----DELLPKALEVAER-LAAGsQTAIRWTKYALNNWLRMAgPTfdtslalefmgfsgPDVREGL 254

                        250
                 ....*....|...
gi 530391275 320 LAFKEKRPPRYKG 332
Cdd:PRK07327 255 ASLREKRAPDFPG 267
PRK05981 PRK05981
enoyl-CoA hydratase/isomerase;
111-332 1.30e-13

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235661  Cd Length: 266  Bit Score: 69.76  E-value: 1.30e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 111 NSLSKNLIKMLSKAVDALKSDK-KVRTIIIRSEVPGiFCAGADLKER---AKMSSSEVG----------PFVSKIRavin 176
Cdd:PRK05981  26 NAVSIDMLGGLAEALDAIEDGKaEVRCLVLTGAGRG-FCTGANLQGRgsgGRESDSGGDagaaletayhPFLRRLR---- 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 177 diaNLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGK 256
Cdd:PRK05981 101 ---NLPCPIVTAVNGPAAGVGMSFALMGDLILCARSAYFLQAFRRIGLVPDGGSTWLLPRLVGKARAMELSLLGEKLPAE 177

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 257 EAKAVGLISHVLEQNQEGDAAYRKALDLA----------REFLPQGPVAMRVAKLAINQGMETIP--TKDRLEGLLAFKE 324
Cdd:PRK05981 178 TALQWGLVNRVVDDAELMAEAMKLAHELAngptvalgliRKLYWDSPENDFEEQLNLEREAQRIAgkTEDFKEGVGAFLQ 257


                 ....*...
gi 530391275 325 KRPPRYKG 332
Cdd:PRK05981 258 KRPAQFKG 265
PRK08259 PRK08259
crotonase/enoyl-CoA hydratase family protein;
145-291 1.52e-13

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236205  Cd Length: 254  Bit Score: 69.54  E-value: 1.52e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 145 GIFCAGADLKERAKMSSSEV-----GPF-VSKIRavindianLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLV 218
Cdd:PRK08259  58 GTFCAGADLKAVGTGRGNRLhpsgdGPMgPSRMR--------LSKPVIAAVSGYAVAGGLELALWCDLRVAEEDAVFGVF 129

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 530391275 219 ETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEAKAVGLISHVLEQNQEGDAAYRKALDLARefLPQ 291
Cdd:PRK08259 130 CRRWGVPLIDGGTVRLPRLIGHSRAMDLILTGRPVDADEALAIGLANRVVPKGQARAAAEELAAELAA--FPQ 200
PRK05864 PRK05864
enoyl-CoA hydratase; Provisional
 95-330 1.56e-13

enoyl-CoA hydratase; Provisional


Pssm-ID: 168278 [Multi-domain]  Cd Length: 276  Bit Score: 69.86  E-value: 1.56e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275  95 DHYR--IVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGiFCAGADLKERAKMSSSE-VGPFVSKI 171
Cdd:PRK05864  14 DHPRpeIALITLNRPERMNSMAFDVMVPLKEALAEVSYDNSVRVVVLTGAGRG-FSSGADHKSAGVVPHVEgLTRPTYAL 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 172 RA------VINDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKM-------GLVETKLaiipggGGTQRLPRAI 238
Cdd:PRK05864  93 RSmellddVILALRRLHQPVIAAVNGPAIGGGLCLALAADIRVASSSAYFraaginnGLTASEL------GLSYLLPRAI 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 239 GMSLAKELIFSARVLDGKEAKAVGLISHVLEQNQEGDAAY----------RKALDLAREFLPQGPVAMRVAKLAINQGME 308
Cdd:PRK05864 167 GSSRAFEIMLTGRDVDAEEAERIGLVSRQVPDEQLLDTCYaiaarmagfsRPGIELTKRTLWSGLDAASLEAHMQAEGLG 246

                        250       260
                 ....*....|....*....|....*.
gi 530391275 309 T----IPTKDRLEGLLAFKEKRPPRY 330
Cdd:PRK05864 247 QlfvrLLTANFEEAVAARAEKRPPVF 272
PRK07110 PRK07110
polyketide biosynthesis enoyl-CoA hydratase; Validated
 98-286 2.22e-12

polyketide biosynthesis enoyl-CoA hydratase; Validated


Pssm-ID: 235936  Cd Length: 249  Bit Score: 65.76  E-value: 2.22e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275  98 RIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSeVPGIFCAGADLK-----ERAKMSSSEVgPFVSKIr 172
Cdd:PRK07110  14 GIAQVTMQDRVNKNAFSDELCDQLHEAFDTIAQDPRYKVVILTG-YPNYFATGGTQEgllslQTGKGTFTEA-NLYSLA- 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 173 avindiANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARV 252
Cdd:PRK07110  91 ------LNCPIPVIAAMQGHAIGGGLVLGLYADIVVLSRESVYTANFMKYGFTPGMGATAILPEKLGLALGQEMLLTARY 164

                        170       180       190
                 ....*....|....*....|....*....|....
gi 530391275 253 LDGKEAKAVGLISHVLEQNQEGDAAYRKALDLAR 286
Cdd:PRK07110 165 YRGAELKKRGVPFPVLPRAEVLEKALELARSLAE 198
PRK06072 PRK06072
enoyl-CoA hydratase; Provisional
 95-333 2.23e-12

enoyl-CoA hydratase; Provisional


Pssm-ID: 168377 [Multi-domain]  Cd Length: 248  Bit Score: 65.96  E-value: 2.23e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275  95 DHYRIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGiFCAGADLkerakmsSSEVGPFVSKIRA- 173
Cdd:PRK06072   6 SREGYAIVTMSRPDKLNALNLEMRNEFISKLKQINADPKIRVVIVTGEGRA-FCVGADL-------SEFAPDFAIDLREt 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 174 ---VINDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELI--- 247
Cdd:PRK06072  78 fypIIREIRFSDKIYISAINGVTAGACIGIALSTDFKFASRDVKFVTAFQRLGLASDTGVAYFLLKLTGQRFYEILVlgg 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 248 -FSArvldgKEAKAVGLISHVleqnqegDAAYRKALDLAREFLpQGP-----VAMRVAKLAINQGMETI----------- 310
Cdd:PRK06072 158 eFTA-----EEAERWGLLKIS-------EDPLSDAEEMANRIS-NGPfqsyiAAKRMINLVLYNDLEEFleyesaiqgyl 224

                        250       260
                 ....*....|....*....|....
gi 530391275 311 -PTKDRLEGLLAFKEKRPPRYKGE 333
Cdd:PRK06072 225 gKTEDFKEGISSFKEKREPKFKGI 248
PRK05674 PRK05674
gamma-carboxygeranoyl-CoA hydratase; Validated
 102-333 1.23e-11

gamma-carboxygeranoyl-CoA hydratase; Validated


Pssm-ID: 168168  Cd Length: 265  Bit Score: 64.06  E-value: 1.23e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 102 LGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGiFCAGADL---KERAKMSSSEVGPFVSKIRAVINDI 178
Cdd:PRK05674  19 LWLSRADKNNAFNAQMIRELILALDQVQSDASLRFLLLRGRGRH-FSAGADLawmQQSADLDYNTNLDDARELAELMYNL 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 179 ANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTqRLPRAIGMSLAKELIFSARVLDGKEA 258
Cdd:PRK05674  98 YRLKIPTLAVVQGAAFGGALGLISCCDMAIGADDAQFCLSEVRIGLAPAVISP-FVVKAIGERAARRYALTAERFDGRRA 176

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 259 KAVGLISHVLEQnQEGDAAYRKALDlarEFLPQGPVAMRVAK------------LAINQGMETIPTKDRL-----EGLLA 321
Cdd:PRK05674 177 RELGLLAESYPA-AELEAQVEAWIA---NLLLNSPQALRASKdllrevgdgelsPALRRYCENAIARIRVsaegqEGLRA 252

                        250
                 ....*....|..
gi 530391275 322 FKEKRPPRYKGE 333
Cdd:PRK05674 253 FLEKRTPAWQTD 264
PRK07938 PRK07938
enoyl-CoA hydratase family protein;
121-317 1.71e-11

enoyl-CoA hydratase family protein;


Pssm-ID: 181174  Cd Length: 249  Bit Score: 63.45  E-value: 1.71e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 121 LSKAVDALKSDKKVRTIIIRSEVPGiFCAGADLKERAKMSSSEV------GPFVSkIRAVINDianlPVPTIAAIDGLAL 194
Cdd:PRK07938  33 LADAITAAGADPDTRVVVLRAEGRG-FNAGVDIKELQATPGFTAlidanrGCFAA-FRAVYEC----AVPVIAAVHGFCL 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 195 GGGLELALACDIRVAASSAKMGLVETKLAIIpgGGGTQrLPRAIGMSLAKELIFSARVLDGKEAKAVGLISHVLEQNQEG 274
Cdd:PRK07938 107 GGGIGLVGNADVIVASDDATFGLPEVDRGAL--GAATH-LQRLVPQHLMRALFFTAATITAAELHHFGSVEEVVPRDQLD 183

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 530391275 275 DAayrkALDLAREFLPQGPVAMRVAKLAINqGMETIPTKD--RLE 317
Cdd:PRK07938 184 EA----ALEVARKIAAKDTRVIRAAKEALN-GIDPQDVERsyRWE 223
PRK07396 PRK07396
dihydroxynaphthoic acid synthetase; Validated
 104-331 2.96e-11

dihydroxynaphthoic acid synthetase; Validated


Pssm-ID: 180958 [Multi-domain]  Cd Length: 273  Bit Score: 62.99  E-value: 2.96e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 104 INRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGIFCAGADLKERAK---MSSSEVGPFvsKIRAVINDIAN 180
Cdd:PRK07396  28 INRPEVRNAFRPKTVKEMIDAFADARDDDNIGVIILTGAGDKAFCSGGDQKVRGYggyVDDDGVPRL--NVLDLQRLIRT 105

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 181 LPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEAKA 260
Cdd:PRK07396 106 CPKPVIAMVAGYAIGGGHVLHLVCDLTIAADNAIFGQTGPKVGSFDGGYGASYLARIVGQKKAREIWFLCRQYDAQEALD 185

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 261 VGLISHV--LEQNQEgdaayrKALDLAREFLPQGPVAMRVAKLAIN------QGMETIP---------TKDRLEGLLAFK 323
Cdd:PRK07396 186 MGLVNTVvpLADLEK------ETVRWCREMLQNSPMALRCLKAALNadcdgqAGLQELAgnatmlfymTEEAQEGRNAFN 259


                 ....*...
gi 530391275 324 EKRPPRYK 331
Cdd:PRK07396 260 EKRQPDFS 267
PRK08788 PRK08788
enoyl-CoA hydratase; Validated
 118-300 7.04e-10

enoyl-CoA hydratase; Validated


Pssm-ID: 236338  Cd Length: 287  Bit Score: 59.15  E-value: 7.04e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 118 IKMLSKAVDALKSDKK--VRTIIIRSEVPGIFCAGADL---------KERAKMsssevgpfVSKIRAVINDI------AN 180
Cdd:PRK08788  48 IMNLQRAIRQRLDDSGlpVDFWVLASDVPGVFNLGGDLalfaeliraGDRDAL--------LAYARACVDGVhafhrgFG 119

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 181 LPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEAKA 260
Cdd:PRK08788 120 AGAISIALVQGDALGGGFEAALSHHTIIAERGAKMGFPEILFNLFPGMGAYSFLARRVGPKLAEELILSGKLYTAEELHD 199

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 530391275 261 VGLISHVLEQNQeGDAAYRKALDLAREfLPQGPVAMRVAK 300
Cdd:PRK08788 200 MGLVDVLVEDGQ-GEAAVRTFIRKSKR-KLNGWRAMLRAR 237
PRK08290 PRK08290
enoyl-CoA hydratase; Provisional
 98-305 1.09e-09

enoyl-CoA hydratase; Provisional


Pssm-ID: 236220 [Multi-domain]  Cd Length: 288  Bit Score: 58.43  E-value: 1.09e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275  98 RIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGiFCAGADLKERAKMSSSEVGPF---VSKIRAV 174
Cdd:PRK08290  13 RIARITLNRPEARNAQNRQMLYELDAAFRRAEADDAVRVIVLAGAGKH-FSAGHDLGSGTPGRDRDPGPDqhpTLWWDGA 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 175 IND-------------------IANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIipggGGTQRL- 234
Cdd:PRK08290  92 TKPgveqryarewevylgmcrrWRDLPKPTIAQVQGACIAGGLMLAWVCDLIVASDDAFFSDPVVRMGI----PGVEYFa 167

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 530391275 235 -PRAIGMSLAKELIFSARVLDGKEAKAVGLISHV-----LEQnqegdaayrKALDLAREFLPQGPVAMRVAKLAINQ 305
Cdd:PRK08290 168 hPWELGPRKAKELLFTGDRLTADEAHRLGMVNRVvprdeLEA---------ETLELARRIAAMPPFGLRLTKRAVNQ 235
PLN03214 PLN03214
probable enoyl-CoA hydratase/isomerase; Provisional
 111-303 1.92e-09

probable enoyl-CoA hydratase/isomerase; Provisional


Pssm-ID: 215635  Cd Length: 278  Bit Score: 57.58  E-value: 1.92e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 111 NSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEV-PGIFCAGADLKE--RAKMSSSEVGPFVSKIRAVINDIANLPVPTIA 187
Cdd:PLN03214  33 NSMTLAMWRSLDDALTALENDPTVRGVVFASGLrRDVFTAGNDIAElyAPKTSAARYAEFWLTQTTFLVRLLRSRLATVC 112

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 188 AIDGLALGGGLELALACDIRVAASSAKMGLVETKLAI-IPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEAKAVGLISH 266
Cdd:PLN03214 113 AIRGACPAGGCAVSLCCDYRLQTTEGTMGLNEVALGIpVPKFWARLFMGRVIDRKVAESLLLRGRLVRPAEAKQLGLIDE 192

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 530391275 267 VLEQNQEGDAAYRKaldlAREFLPQGPVAMRVAKLAI 303
Cdd:PLN03214 193 VVPAAALMEAAASA----MERALKLPSAARAATKALL 225
PRK09120 PRK09120
p-hydroxycinnamoyl CoA hydratase/lyase; Validated
 105-303 2.01e-09

p-hydroxycinnamoyl CoA hydratase/lyase; Validated


Pssm-ID: 236383  Cd Length: 275  Bit Score: 57.71  E-value: 2.01e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 105 NRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGiFCAGADLKE--RAKMSSSEVGpfVSKIRAVIND----I 178
Cdd:PRK09120  24 NRPEKRNAMSPTLNREMIDVLDALEFDDDAGVLVLTGAGDA-WSAGMDLKEyfRETDAQPEIL--QERIRREAYGwwrrL 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 179 ANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEA 258
Cdd:PRK09120 101 RWYQKPTIAMVNGWCFGGGFSPLVACDLAIAADEAQFGLSEINWGIPPGGGVSKAMADTVGHRDALYYIMTGETFTGRKA 180

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 530391275 259 KAVGLISHVLEQNQEgDAAYRKaldLAREFLPQGPVAMRVAKLAI 303
Cdd:PRK09120 181 AEMGLVNESVPLAQL-RARTRE---LAAKLLEKNPVVLRAAKDGF 221
PRK06023 PRK06023
crotonase/enoyl-CoA hydratase family protein;
96-300 1.97e-08

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 168351  Cd Length: 251  Bit Score: 54.41  E-value: 1.97e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275  96 HYRIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSeVPGIFCAGADLKE--RAKMSSSEVGPfvsKIRA 173
Cdd:PRK06023  13 HPGVQVIRFNRPEKKNAITRAMYATMAKALKAADADDAIRAHVFLG-TEGCFSAGNDMQDflAAAMGGTSFGS---EILD 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 174 VINDIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVL 253
Cdd:PRK06023  89 FLIALAEAEKPIVSGVDGLAIGIGTTIHLHCDLTFASPRSLFRTPFVDLALVPEAGSSLLAPRLMGHQRAFALLALGEGF 168

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 530391275 254 DGKEAKAVGLISHVLEQnqegDAAYRKALDLAREFLPQGPVAMRVAK 300
Cdd:PRK06023 169 SAEAAQEAGLIWKIVDE----EAVEAETLKAAEELAAKPPQALQIAR 211
PRK07260 PRK07260
enoyl-CoA hydratase; Provisional
 99-326 2.49e-08

enoyl-CoA hydratase; Provisional


Pssm-ID: 180910 [Multi-domain]  Cd Length: 255  Bit Score: 53.98  E-value: 2.49e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275  99 IVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPgIFCAGADLKERAKMSSSEVGPFVSKIRAVINDI 178
Cdd:PRK07260  12 LATLTLNRPEVSNGFNIPMCQEILEALRLAEEDPSVRFLLINANGK-VFSVGGDLVEMKRAVDEDDVQSLVKIAELVNEI 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 179 A----NLPVPTIAAIDGLALGGGLELALACDIRVAASSAKM--GLVETKLAiiPGGGGTQRLPRAIGMSLAKELIFSARV 252
Cdd:PRK07260  91 SfaikQLPKPVIMCVDGAVAGAAANMAVAADFCIASTKTKFiqAFVGVGLA--PDAGGLFLLTRAIGLNRATHLAMTGEA 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 253 LDGKEAKAVGLISHVLEQNQegdaaYRKALDLAREFLPQGPV----AMR-------------VAKLAINQGMETIPTKDR 315
Cdd:PRK07260 169 LTAEKALEYGFVYRVAESEK-----LEKTCEQLLKKLRRGSSnsyaAIKslvwesffkgwedYAKLELALQESLAFKEDF 243

                        250
                 ....*....|.
gi 530391275 316 LEGLLAFKEKR 326
Cdd:PRK07260 244 KEGVRAFSERR 254
PRK08272 PRK08272
crotonase/enoyl-CoA hydratase family protein;
98-308 1.10e-07

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236213  Cd Length: 302  Bit Score: 52.35  E-value: 1.10e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275  98 RIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGiFCAGADLKERAK-MSSSEVGPFVSKIRAVIN 176
Cdd:PRK08272  19 RIARITLNRPEKGNAITADTPLELRAAVERADLDPGVHVILVSGAGKG-FCAGYDLSAYAEgSSSGGGGGAYPGKRQAVN 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 177 DIANLP------------------------VPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGG--- 229
Cdd:PRK08272  98 HLPDDPwdpmidyqmmsrfvrgfmslwhahKPTVAKVHGYCVAGGTDIALHCDQVIAADDAKIGYPPTRVWGVPATGmwa 177

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 230 ---GTQRlpraigmslAKELIFSARVLDGKEAKAVGLISHVLEQNQEGDAAYRKALDLAreFLPQGPVAMrvAKLAINQG 306
Cdd:PRK08272 178 yrlGPQR---------AKRLLFTGDCITGAQAAEWGLAVEAVPPEELDERTERLVERIA--AVPVNQLAM--VKLAVNSA 244


                 ..
gi 530391275 307 ME 308
Cdd:PRK08272 245 LL 246
PRK08321 PRK08321
1,4-dihydroxy-2-naphthoyl-CoA synthase;
99-331 1.30e-07

1,4-dihydroxy-2-naphthoyl-CoA synthase;


Pssm-ID: 181386  Cd Length: 302  Bit Score: 52.33  E-value: 1.30e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275  99 IVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIR----SEVPGI--FCAGADLKERA----KMSSSEVGPFV 168
Cdd:PRK08321  35 TVRIAFDRPEVRNAFRPHTVDELYRALDHARMSPDVGCVLLTgngpSPKDGGwaFCSGGDQRIRGrdgyQYAEGDEADTV 114

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 169 SKIRA-------VINDIANLPVPTIAAIDGLALGGGLELALACDIRVAASS-AKMGLVETKLAIIPGGGGTQRLPRAIGM 240
Cdd:PRK08321 115 DPARAgrlhileVQRLIRFMPKVVIAVVPGWAAGGGHSLHVVCDLTLASREhARFKQTDADVGSFDGGYGSAYLARQVGQ 194

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 241 SLAKELIFSARVLDGKEAKAVGLISHVLEQNQEGDAayrkALDLAREFLPQGPVAMRVAKLAIN---QGM--------ET 309
Cdd:PRK08321 195 KFAREIFFLGRTYSAEEAHDMGAVNAVVPHAELETE----ALEWAREINGKSPTAMRMLKYAFNltdDGLvgqqlfagEA 270

                        250       260
                 ....*....|....*....|....*.
gi 530391275 310 IP----TKDRLEGLLAFKEKRPPRYK 331
Cdd:PRK08321 271 TRlaymTDEAQEGRDAFLEKRDPDWS 296
ECH_2 pfam16113
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
 111-269 1.05e-06

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.


Pssm-ID: 465024 [Multi-domain]  Cd Length: 331  Bit Score: 49.78  E-value: 1.05e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275  111 NSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGIFCAGADLKERAKM----SSSEVGPFVSKIRAVINDIANLPVPTI 186
Cdd:pfam16113  13 NALNLEMVRALLAALKAWEDDPAVKLVVLKGAGERAFCAGGDVRALYEAakagGGEAGRDFFREEYRLNYLIATYPKPYV 92

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275  187 AAIDGLalggglelalaCDIRVAASSAKMGLVETKLAIIPGGGGT---QRLPRAIGMSLAkeliFSARVLDGKEAKAVGL 263
Cdd:pfam16113  93 ALMDGIvmgggvglsvhGSFRVVTERTRFAMPETAIGLFPDVGGSyflSRLPGELGLYLA----LTGARLNGADALAAGL 168


                  ....*.
gi 530391275  264 ISHVLE 269
Cdd:pfam16113 169 ATHYVP 174
PRK05617 PRK05617
3-hydroxyisobutyryl-CoA hydrolase; Provisional
 98-282 7.19e-05

3-hydroxyisobutyryl-CoA hydrolase; Provisional


Pssm-ID: 235533 [Multi-domain]  Cd Length: 342  Bit Score: 44.04  E-value: 7.19e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275  98 RIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGIFCAGADLKE-----RAKMSSSEVGPFVSKIR 172
Cdd:PRK05617  12 GVGVITLNRPKALNALSLEMIRAIDAALDAWEDDDAVAAVVIEGAGERGFCAGGDIRAlyeaaRAGDPLAADRFFREEYR 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 173 avIN-DIANLPVPTIAAIDGLALGGGLELALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRA---IGMSLAkeliF 248
Cdd:PRK05617  92 --LNaLIARYPKPYIALMDGIVMGGGVGISAHGSHRIVTERTKMAMPETGIGFFPDVGGTYFLSRApgaLGTYLA----L 165

                        170       180       190
                 ....*....|....*....|....*....|....
gi 530391275 249 SARVLDGKEAKAVGLISHVLEQNQEgdAAYRKAL 282
Cdd:PRK05617 166 TGARISAADALYAGLADHFVPSADL--PALLDAL 197
PLN02267 PLN02267
enoyl-CoA hydratase/isomerase family protein
 109-189 1.82e-03

enoyl-CoA hydratase/isomerase family protein


Pssm-ID: 215151  Cd Length: 239  Bit Score: 39.31  E-value: 1.82e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530391275 109 GKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGIFCAGADLK--ERAKMSSSEVGPFVSKIRAVINDIANLPVPTI 186
Cdd:PLN02267  19 GEHRLNPTLIDSIRSALRQVKSQATPGSVLITTAEGKFFSNGFDLAwaQAAGSAPSRLHLMVAKLRPLVADLISLPMPTI 98


                 ...
gi 530391275 187 AAI 189
Cdd:PLN02267  99 AAV 101
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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