|
Name |
Accession |
Description |
Interval |
E-value |
| Eukaryotic_PFK |
cd00764 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
13-796 |
0e+00 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include eukaryotic ATP-dependent phosphofructokinases. These have evolved from the bacterial PFKs by gene duplication and fusion events and exhibit complex allosteric behavior.
Pssm-ID: 238389 [Multi-domain] Cd Length: 762 Bit Score: 1448.10 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 13 GAGKAIGVLTSGGDAQGMNAAVRAVTRMGIYVGAKVFLIYEeqrmpyclspsprgrfgarppswGYEGLVEGGENIKQAN 92
Cdd:cd00764 1 GAGKAIAVLTSGGDAQGMNAAVRAVVRMGIYVGAKVFFVYE-----------------------GYEGLVKGGDYIKQAE 57
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 93 WLSVSNIIQLGGTIIGSARCKAFTTREGRRAAAYNLVQHGITNLCVIGGDGSLTGANIFRSEWGSLLEELVAEGKISETT 172
Cdd:cd00764 58 WESVSNWLQEGGTIIGSARCKEFREREGRLQAAYNLIQRGITNLCVIGGDGSLTGADLFRSEWPSLLEELVKDGKITEEE 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 173 ARTYSHLNIAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITTTAQSHQRTFVLEVMGRHCGYLALVSALASGADWLF 252
Cdd:cd00764 138 VAKYQHLNIVGMVGSIDNDFCGTDMTIGTDSALHRICEVVDAITTTAQSHQRTFVLEVMGRHCGYLALVSGLATGADWIF 217
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 253 IPEAPPEDGWENFMCERLGETRSRGSRLNIIIIAEGAIDRNGKPISSSYVKDLVVQRLGFDTRVTVLGHVQRGGTPSAFD 332
Cdd:cd00764 218 IPERPPEDGWEDQMCRRLSEHRSRGKRLNIIIVAEGAIDDQLKPITSEDVKDLVVERLGLDTRVTTLGHVQRGGTPSAFD 297
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 333 RILSSKMGMEAVMALLEATPDTPACVVTLSGNQSVRLPLMECVQMTKEVQKAMDDKRFDEATQLRGGSFENNWNIYKLLA 412
Cdd:cd00764 298 RILASLMGVEAVMALLEATPDTPACVVSLNGNKAVRLPLMECVQLTKDVQKAMDEKRFDEAAALRGKSFDKNWNLYKLLA 377
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 413 HQKPPK--EKSNFSLAILNVGAPAAGMNAAVRSAVRTGISHGHTVYVVHDGFEGLAKGQVQEVGWHDVAGWLGRGGSMLG 490
Cdd:cd00764 378 IELPQPlpEKTNLNIAIVNVGAPAAGMNAAVRSAVRYGLAHGHRPYAIYDGFEGLAKGQIVELGWIDVGGWTGRGGSELG 457
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 491 TKRTLPKGQLESIVENIRIYGIHALLVVGGFEAYEGVLQLVEARGRYEELCIVMCVIPATISNNVPGTDFSLGSDTAVNA 570
Cdd:cd00764 458 TKRTLPKKDLETIAYNFQKYGIDGLIIVGGFEAYKGLLQLREAREQYEEFCIPMVLIPATVSNNVPGTDFSLGSDTALNA 537
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 571 AMESCDRIKQSASGTKRRVFIVETMGGYCGYLATVTGIAVGADAAYVFEDPFNIHDLKVNVEHMTEKMKTDIQRGLVLRN 650
Cdd:cd00764 538 LMKYCDRIKQSASGTKRRVFIVETMGGYCGYLATMTGLAVGADAAYVFEEPFNIRDLQENVEHLTEKMKTTIGRGLVLRN 617
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 651 EKCHDYYTTEFLYNLYSSEGKGVFDCRTNVLGHLQQGGAPTPFDRNYGTKLGVKAMLWLSEKLREVYRKGRVFANAPDSA 730
Cdd:cd00764 618 EKCNENYTTVFTYELYSEEGKGVFDCRTNVLGHVQQGGAPSPFDRNFGTKFAVKAMKWIEQKLKENYAAGNEFANDPDFN 697
|
730 740 750 760 770 780
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 530419267 731 CVIGLKKKAVAFSPVTELKKDTdFEHRMPREQWWLSLRLMLKMLAQYRISMAAYVSGELEHVTRRT 796
Cdd:cd00764 698 CVNGVKKYAVLFEPVEELKQTT-FEHRIPKEQWWLSLRPLLKILAKYKISADISDHGQLEHVTRGQ 762
|
|
| 6PF1K_euk |
TIGR02478 |
6-phosphofructokinase, eukaryotic type; Members of this family are eukaryotic (with one ... |
16-778 |
0e+00 |
|
6-phosphofructokinase, eukaryotic type; Members of this family are eukaryotic (with one exception) ATP-dependent 6-phosphofructokinases (EC 2.7.1.11) in which two tandem copies of the phosphofructokinase are found. Members are found, often including several isozymes, in animals and fungi and in the bacterium Propionibacterium acnes KPA171202 (a human skin commensal).
Pssm-ID: 274152 [Multi-domain] Cd Length: 746 Bit Score: 1198.31 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 16 KAIGVLTSGGDAQGMNAAVRAVTRMGIYVGAKVFLIYEeqrmpyclspsprgrfgarppswGYEGLVEGGENIKQANWLS 95
Cdd:TIGR02478 1 KRIAVLTSGGDAQGMNAAVRAVVRMAIYVGCRVYAIRE-----------------------GYQGLVDGGDNIEEAQWED 57
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 96 VSNIIQLGGTIIGSARCKAFTTREGRRAAAYNLVQHGITNLCVIGGDGSLTGANIFRSEWGSLLEELVAEGKISETTART 175
Cdd:TIGR02478 58 VRGILSLGGTIIGTARCKEFRERPGRLKAARNLVSNGIDALVVIGGDGSLTGADLFREEWPSLLEELVDTGKITAEQAEE 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 176 YSHLNIAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITTTAQSHQRTFVLEVMGRHCGYLALVSALASGADWLFIPE 255
Cdd:TIGR02478 138 HRHLTIVGLVGSIDNDMCGTDMTIGADSALHRICEAIDAISSTAQSHQRAFVVEVMGRHCGYLALMAAIATGADYVFIPE 217
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 256 APPEDGWENFMCERLGETRSRGSRLNIIIIAEGAIDRNGKPISSSYVKDLVVQRLGFDTRVTVLGHVQRGGTPSAFDRIL 335
Cdd:TIGR02478 218 RPPEEGWEDQLCHKLKRNRKAGKRKTIVIVAEGAIDRDLNPITSEDVKDVLVERLGLDTRITVLGHVQRGGAPSAFDRIL 297
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 336 SSKMGMEAVMALLEATPDTPACVVTLSGNQSVRLPLMECVQMTKEVQKAMDDKRFDEATQLRGGSFENNWNIYKLLAHQK 415
Cdd:TIGR02478 298 ATRQGVEAVLAVLESTPETPSPVISLRGNKIVRKPLVEAVAQTKTVAKAIEEKDFDEAMRLRGREFAENLETFLFLSIPD 377
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 416 PPK-----EKSNFSLAILNVGAPAAGMNAAVRSAVRTGISHGHTVYVVHDGFEGLAKGQVQEVGWHDVAGWLGRGGSMLG 490
Cdd:TIGR02478 378 DDKklvpsEASRLRIAIIHVGAPAGGMNAATRSAVRYALARGHTVIAIHNGFSGLARHDVRELTWSDVEGWVGEGGSELG 457
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 491 TKRTLPKGQLESIVENIRIYGIHALLVVGGFEAYEGVLQLVEARGRYEELCIVMCVIPATISNNVPGTDFSLGSDTAVNA 570
Cdd:TIGR02478 458 TNRSLPGDDLGTIAYYFQQHKIDGLIIIGGFEAFEALYQLDAAREKYPAFRIPMVVIPATISNNVPGTEYSLGSDTALNE 537
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 571 AMESCDRIKQSASGTKRRVFIVETMGGYCGYLATVTGIAVGADAAYVFEDPFNIHDLKVNVEHMTEKMKTDIQRGLVLRN 650
Cdd:TIGR02478 538 ITEYCDNIKQSASASKRRVFVVETMGGYSGYLATMAGLATGADAAYIPEEGISLKDLQEDIEHLKETFAEGRAGKLILRN 617
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 651 EKCHDYYTTEFLYNLYSSEGKGVFDCRTNVLGHLQQGGAPTPFDRNYGTKLGVKAMLWLSEKLREVYRKGRVFANaPDSA 730
Cdd:TIGR02478 618 EKASKVYTTDFIARIISEEGKGRFDARTAVLGHMQQGGSPSPFDRVRATRLAIRAVDFIEEKIKANKHADKLSAD-DTSA 696
|
730 740 750 760
....*....|....*....|....*....|....*....|....*....
gi 530419267 731 CVIGLKKKAVAFSPV-TELKKDTDFEHRMPREQWWLSLRLMLKMLAQYR 778
Cdd:TIGR02478 697 VVIGIRGSNVLFTPVkQLLANETDFEHRRPKNQWWLQLRPLVRILAGRD 745
|
|
| PFK |
cd00363 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
16-406 |
0e+00 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to PFK family that includes ATP- and pyrophosphate (PPi)- dependent phosphofructokinases. Some members evolved by gene duplication and thus have a large C-terminal/N-terminal extension comprising a second PFK domain. Generally, ATP-PFKs are allosteric homotetramers, and PPi-PFKs are dimeric and nonallosteric except for plant PPi-PFKs which are allosteric heterotetramers.
Pssm-ID: 238216 [Multi-domain] Cd Length: 338 Bit Score: 531.10 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 16 KAIGVLTSGGDAQGMNAAVRAVTRMGIYVGAKVFLIYEeqrmpyclspsprgrfgarppswGYEGLVEGgeNIKQANWLS 95
Cdd:cd00363 1 KKIGVLTSGGDAPGMNAAIRGVVRSAIAEGLEVYGIYE-----------------------GYAGLVEG--DIKELDWES 55
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 96 VSNIIQLGGTIIGSARCKAFTTREGRRAAAYNLVQHGITNLCVIGGDGSLTGANIFRSEWGSlleelvaegkisettarT 175
Cdd:cd00363 56 VSDIINRGGTIIGSARCKEFRTEEGRAKAAENLKKHGIDALVVIGGDGSYTGADLLTEEWPS-----------------K 118
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 176 YSHLNIAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITTTAQSHQRTFVLEVMGRHCGYLALVSALASGADWLFIPE 255
Cdd:cd00363 119 YQGFNVIGLPGTIDNDIKGTDYTIGFDTALKTIVEAIDRIRDTASSHQRTFVVEVMGRHCGDIALEAGLATGADIIFIPE 198
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 256 APPEDGWENFMCERLGETRSRGSRLNIIIIAEGAIDRNGKPISSSYVKDLVVQRLGFDTRVTVLGHVQRGGTPSAFDRIL 335
Cdd:cd00363 199 EPAADEWEEEMVDVIKKRRERGKRHGIVIVAEGAIDFIPKPITEKLLAKLVEERLGFDTRATVLGHVQRGGTPTAFDRIL 278
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 530419267 336 SSKMGMEAVMALLEATPDTPACVVTLSGNQSVRLPLMECVQMTKEVQkamddkrfdeaTQLRGGSFENNWN 406
Cdd:cd00363 279 ASRLGAEAVELLLEGTGGTPVGIQNLNENQVVRHPLTEAVNMTKRVG-----------VDLEGRPFKKFAK 338
|
|
| PFK |
pfam00365 |
Phosphofructokinase; |
18-344 |
4.35e-136 |
|
Phosphofructokinase;
Pssm-ID: 459783 [Multi-domain] Cd Length: 271 Bit Score: 404.03 E-value: 4.35e-136
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 18 IGVLTSGGDAQGMNAAVRAVTRMGIYVGAKVFLIYEeqrmpyclspsprgrfgarppswGYEGLVEGgeNIKQANWLSVS 97
Cdd:pfam00365 2 IGILTSGGDAPGMNAAIRAVVRTAIYRGHEVYGIRN-----------------------GYEGLVEG--DIDELTWRDVS 56
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 98 NIIQLGGTIIGSARCKAFTTREGRRAAAYNLVQHGITNLCVIGGDGSLTGANIFRSEWGslleelvaegkisettartys 177
Cdd:pfam00365 57 GILNRGGTILGTSRSKPFKTEEGREKIAENLKKLGIDALVVIGGDGSLTGANKLSEERG--------------------- 115
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 178 hLNIAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITTTAQSHQRTFVLEVMGRHCGYLALVSALASGADWLFIPEAP 257
Cdd:pfam00365 116 -IPVVGIPKTIDNDIPGTDYTIGFDTALNTIVEAIDRIRDTASSHNRVFVVEVMGRHCGWLALMAGLAGGADAILIPEIP 194
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 258 PEdgwENFMCERLgETRSRGSRLNIIIIAEGAIDrngkpisSSYVKDLVVQRLGFDTRVTVLGHVQRGGTPSAFDRILSS 337
Cdd:pfam00365 195 FD---IEELCEKI-KELRKGKRFSIIVVAEGASD-------GEFLAKLIEEGTGIETRVTVLGHVQRGGTPSAFDRILAT 263
|
....*..
gi 530419267 338 KMGMEAV 344
Cdd:pfam00365 264 RLGVKAV 270
|
|
| PFK |
pfam00365 |
Phosphofructokinase; |
425-706 |
3.58e-121 |
|
Phosphofructokinase;
Pssm-ID: 459783 [Multi-domain] Cd Length: 271 Bit Score: 365.51 E-value: 3.58e-121
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 425 LAILNVGAPAAGMNAAVRSAVRTGISHGHTVYVVHDGFEGLAKGQVQEVGWHDVAGWLGRGGSMLGTKRTLPKGQLES-- 502
Cdd:pfam00365 2 IGILTSGGDAPGMNAAIRAVVRTAIYRGHEVYGIRNGYEGLVEGDIDELTWRDVSGILNRGGTILGTSRSKPFKTEEGre 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 503 -IVENIRIYGIHALLVVGGFEAYEGVLQLVEARGryeelcIVMCVIPATISNNVPGTDFSLGSDTAVNAAMESCDRIKQS 581
Cdd:pfam00365 82 kIAENLKKLGIDALVVIGGDGSLTGANKLSEERG------IPVVGIPKTIDNDIPGTDYTIGFDTALNTIVEAIDRIRDT 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 582 ASGTkRRVFIVETMGGYCGYLATVTGIAVGADAAYVFEDPFNIHDLKVNVEHMTeKMKTDIqrgLVLRNEKCHDyytTEF 661
Cdd:pfam00365 156 ASSH-NRVFVVEVMGRHCGWLALMAGLAGGADAILIPEIPFDIEELCEKIKELR-KGKRFS---IIVVAEGASD---GEF 227
|
250 260 270 280
....*....|....*....|....*....|....*....|....*
gi 530419267 662 LYNLYssEGKGVFDCRTNVLGHLQQGGAPTPFDRNYGTKLGVKAM 706
Cdd:pfam00365 228 LAKLI--EEGTGIETRVTVLGHVQRGGTPSAFDRILATRLGVKAV 270
|
|
| PfkA |
COG0205 |
6-phosphofructokinase [Carbohydrate transport and metabolism]; 6-phosphofructokinase is part ... |
16-381 |
8.14e-117 |
|
6-phosphofructokinase [Carbohydrate transport and metabolism]; 6-phosphofructokinase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439975 [Multi-domain] Cd Length: 344 Bit Score: 357.08 E-value: 8.14e-117
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 16 KAIGVLTSGGDAQGMNAAVRAVTRMGIYVGAKVFLIYEeqrmpyclspsprgrfgarppswGYEGLVEGgeNIKQANWLS 95
Cdd:COG0205 2 KRIGILTSGGDAPGLNAAIRAVVRTAIKYGIEVYGIRD-----------------------GYEGLLEG--DIIDLTRED 56
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 96 VSNIIQLGGTIIGSARCKAFTTREGRRAAAYNLVQHGITNLCVIGGDGSLTGANIFRSEWGslleelvaegkisettart 175
Cdd:COG0205 57 VSGILQRGGTILGSSRSKPFKTEEGREKALENLKKLGIDALVVIGGDGSLDGAAKLAEEYG------------------- 117
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 176 yshLNIAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITTTAQSHQRTFVLEVMGRHCGYLALVSALASGADWLFIPE 255
Cdd:COG0205 118 ---IPVVGIPKTIDNDLPGTDYTIGFDTAVNTAAEAIDRLRDTAASHERVFVVEVMGRHAGWLALAAGLAGGADLILIPE 194
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 256 APPEdgwENFMCERLGETRSRGSRLNIIIIAEGAIDRNGKPISSS---------------YVKDLVVQRLGFDTRVTVLG 320
Cdd:COG0205 195 VPFD---LDKLLEKLKERRKRGKGYSIIVVAEGAGDEDGEAVLEAdtdafghvrlggigeYLAKEIEERTGIETRVTVLG 271
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 530419267 321 HVQRGGTPSAFDRILSSKMGMEAVMALLEatpDTPACVVTLSGNQSVRLPLMECVQMTKEV 381
Cdd:COG0205 272 HLQRGGSPSAFDRVLASRLGAAAVELLLE---GKTGVMVGIRRGEIVLVPLEEVANKEKPV 329
|
|
| PRK03202 |
PRK03202 |
ATP-dependent 6-phosphofructokinase; |
16-388 |
6.80e-116 |
|
ATP-dependent 6-phosphofructokinase;
Pssm-ID: 235111 [Multi-domain] Cd Length: 320 Bit Score: 353.62 E-value: 6.80e-116
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 16 KAIGVLTSGGDAQGMNAAVRAVTRMGIYVGAKVFLIYEeqrmpyclspsprgrfgarppswGYEGLVEGgeNIKQANWLS 95
Cdd:PRK03202 2 KRIGVLTSGGDAPGMNAAIRAVVRTAISEGLEVYGIYD-----------------------GYAGLLEG--DIVKLDLKS 56
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 96 VSNIIQLGGTIIGSARCKAFTTREGRRAAAYNLVQHGITNLCVIGGDGSLTGANIFrSEWGslleelvaegkisettart 175
Cdd:PRK03202 57 VSDIINRGGTILGSARFPEFKDEEGRAKAIENLKKLGIDALVVIGGDGSYMGAKRL-TEHG------------------- 116
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 176 yshLNIAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITTTAQSHQRTFVLEVMGRHCGYLALVSALASGADWLFIPE 255
Cdd:PRK03202 117 ---IPVIGLPGTIDNDIAGTDYTIGFDTALNTAVEAIDRLRDTASSHERVFIVEVMGRHAGDLALHAGIAGGAEVILIPE 193
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 256 AP--PEDgwenfMCERLGETRSRGSRLNIIIIAEGAIDRNGkpisssyVKDLVVQRLGFDTRVTVLGHVQRGGTPSAFDR 333
Cdd:PRK03202 194 VPfdIEE-----LCAKIKKGRERGKKHAIIVVAEGVMPAEE-------LAKEIEERTGLETRVTVLGHIQRGGSPTAFDR 261
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
gi 530419267 334 ILSSKMGMEAVMALLEATPDTpacVVTLSGNQSVRLPLMECV-QMTKEVQKAMDDK 388
Cdd:PRK03202 262 VLASRMGAHAVELLLEGKGGR---MVGIQNNKIVHVPIEEAVeNMKHPFDKDLYEL 314
|
|
| PFKA_ATP |
TIGR02482 |
6-phosphofructokinase; 6-phosphofructokinase (EC 2.7.1.11) catalyzes the addition of phosphate ... |
18-373 |
2.35e-105 |
|
6-phosphofructokinase; 6-phosphofructokinase (EC 2.7.1.11) catalyzes the addition of phosphate from ATP to fructose 6-phosphate to give fructose 1,6-bisphosphate. This represents a key control step in glycolysis. This model hits bacterial ATP-dependent 6-phosphofructokinases which lack a beta-hairpin loop present in TIGR02483 family members. TIGR02483 contains members that are ATP-dependent as well as members that are pyrophosphate-dependent. TIGR02477 represents the pyrophosphate-dependent phosphofructokinase, diphosphate--fructose-6-phosphate 1-phosphotransferase (EC 2.7.1.90). [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 213713 [Multi-domain] Cd Length: 301 Bit Score: 325.84 E-value: 2.35e-105
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 18 IGVLTSGGDAQGMNAAVRAVTRMGIYVGAKVFLIYEeqrmpyclspsprgrfgarppswGYEGLVEGgeNIKQANWLSVS 97
Cdd:TIGR02482 2 IGILTSGGDAPGMNAAIRAVVRTAIYHGFEVYGIRR-----------------------GYKGLING--KIEPLESKNVS 56
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 98 NIIQLGGTIIGSARCKAFTTREGRRAAAYNLVQHGITNLCVIGGDGSLTGANIfrsewgslleeLVAEGKIsettartys 177
Cdd:TIGR02482 57 GIIHRGGTILGTARCPEFKTEEVREKAVENLKKLGIEGLVVIGGDGSYTGAQK-----------LYEEGGI--------- 116
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 178 hlNIAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITTTAQSHQRTFVLEVMGRHCGYLALVSALASGADWLFIPEA- 256
Cdd:TIGR02482 117 --PVIGLPGTIDNDIPGTDYTIGFDTALNTIIDAVDKIRDTATSHERAFVIEVMGRHAGDLALYAGIATGAEIIIIPEFd 194
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 257 -PPEDgwenfMCERLGETRSRGSRLNIIIIAEGAIDRNGKPISSSyVKDlvvqRLGFDTRVTVLGHVQRGGTPSAFDRIL 335
Cdd:TIGR02482 195 yDIDE-----LIQRLKEQHEAGKKHSIIIVAEGNIVGSAKEVAKK-IEE----KTGIETRVTVLGHTQRGGSPSAFDRVL 264
|
330 340 350
....*....|....*....|....*....|....*...
gi 530419267 336 SSKMGMEAVMALLEatpDTPACVVTLSGNQSVRLPLME 373
Cdd:TIGR02482 265 ASRLGAKAVELLLE---GKGGVMIGIQNNKIVTHPIEE 299
|
|
| Bacterial_PFK |
cd00763 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
16-385 |
5.16e-93 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent phosphofructokinases. These are allosrterically regulated homotetramers; the subunits are of about 320 amino acids.
Pssm-ID: 238388 [Multi-domain] Cd Length: 317 Bit Score: 293.93 E-value: 5.16e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 16 KAIGVLTSGGDAQGMNAAVRAVTRMGIYVGAKVFLIYEeqrmpyclspsprgrfgarppswGYEGLVEGgeNIKQANWLS 95
Cdd:cd00763 1 KRIGVLTSGGDAPGMNAAIRGVVRSAIAEGLEVYGIRD-----------------------GYAGLIAG--DIVPLDRYS 55
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 96 VSNIIQLGGTIIGSARCKAFTTREGRRAAAYNLVQHGITNLCVIGGDGSLTGAnifrsewgsllEELVAEGkisettart 175
Cdd:cd00763 56 VSDIINRGGTFLGSARFPEFKDEEGQAKAIEQLKKHGIDALVVIGGDGSYMGA-----------MRLTEHG--------- 115
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 176 yshLNIAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITTTAQSHQRTFVLEVMGRHCGYLALVSALASGADWLFIPE 255
Cdd:cd00763 116 ---FPCVGLPGTIDNDIPGTDYTIGFDTALNTVVEAIDRIRDTSSSHQRISVVEVMGRHCGDIALAAGIAGGAEFIVIPE 192
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 256 AP--PEDgwenfMCERLGETRSRGSRLNIIIIAEGAIDRNGkpisssyVKDLVVQRLGFDTRVTVLGHVQRGGTPSAFDR 333
Cdd:cd00763 193 AEfdREE-----VANRIKAGIERGKKHAIVVVAEGVYDVDE-------LAKEIEEATGFETRATVLGHIQRGGSPTAFDR 260
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|..
gi 530419267 334 ILSSKMGMEAVMALLEAtpdTPACVVTLSGNQSVRLPLMECVQMTKEVQKAM 385
Cdd:cd00763 261 ILASRMGAYAVELLLAG---KGGLAVGIQNEQLVHHDIIDAIENMKPFKKDW 309
|
|
| PFK_mixed |
TIGR02483 |
phosphofructokinase; Members of this family that are characterized, save one, are ... |
18-375 |
7.65e-73 |
|
phosphofructokinase; Members of this family that are characterized, save one, are phosphofructokinases dependent on pyrophosphate (EC 2.7.1.90) rather than ATP (EC 2.7.1.11). The exception is one of three phosphofructokinases from Streptomyces coelicolor. Family members are both bacterial and archaeal. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 274155 [Multi-domain] Cd Length: 324 Bit Score: 241.05 E-value: 7.65e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 18 IGVLTSGGDAQGMNAAVRAVTRMGIYV-GAKVFLIYEeqrmpyclspsprgrfgarppswGYEGLVEGGEnIKQANWLSV 96
Cdd:TIGR02483 2 IGVLTGGGDCPGLNAVIRGVVRRAIAEyGWEVIGIRD-----------------------GWRGLLEGDT-VPLLDLEDV 57
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 97 SNIIQLGGTIIGSARCKAFTT-REGRRAAAYNLVQHGITNLCVIGGDGSLTGANifrsewgslleELVAEGkisettart 175
Cdd:TIGR02483 58 RGILPRGGTILGSSRTNPFKYeEDGDDKIVANLKELGLDALIAIGGDGTLGIAR-----------RLADKG--------- 117
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 176 yshLNIAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITTTAQSHQRTFVLEVMGRHCGYLALVSALASGADWLFIPE 255
Cdd:TIGR02483 118 ---LPVVGVPKTIDNDLEATDYTFGFDTAVEIATEALDRLHTTAESHHRVMVVEVMGRHAGWIALHSGIAGGADVILIPE 194
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 256 APPEdgWENfMCERLGETRSRGSRLNIIIIAEGAIDRNGKPISSSYVKD----------------LVVQRLGFDTRVTVL 319
Cdd:TIGR02483 195 IPFD--IDS-VCEKVRERFARGKRFAIVVVAEGAKPKGGEMVVQEGVKDafghvrlggignwlaeEIERRTGIETRATVL 271
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
gi 530419267 320 GHVQRGGTPSAFDRILSSKMGMEAVMALLEATPDTpacVVTLSGNQSVRLPLMECV 375
Cdd:TIGR02483 272 GHLQRGGSPSAFDRVLATRFGVAAVDLVHEGQFGH---MVALRGTDIVYVPIAEAV 324
|
|
| PfkA |
COG0205 |
6-phosphofructokinase [Carbohydrate transport and metabolism]; 6-phosphofructokinase is part ... |
425-711 |
2.24e-67 |
|
6-phosphofructokinase [Carbohydrate transport and metabolism]; 6-phosphofructokinase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439975 [Multi-domain] Cd Length: 344 Bit Score: 226.88 E-value: 2.24e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 425 LAILNVGAPAAGMNAAVRSAVRTGISHGHTVYVVHDGFEGLAKGQVQEVGWHDVAGWLGRGGSMLGTKRTLPK---GQLE 501
Cdd:COG0205 4 IGILTSGGDAPGLNAAIRAVVRTAIKYGIEVYGIRDGYEGLLEGDIIDLTREDVSGILQRGGTILGSSRSKPFkteEGRE 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 502 SIVENIRIYGIHALLVVGGFEAYEGVLQLVEARGryeelciVMCV-IPATISNNVPGTDFSLGSDTAVNAAMESCDRIKQ 580
Cdd:COG0205 84 KALENLKKLGIDALVVIGGDGSLDGAAKLAEEYG-------IPVVgIPKTIDNDLPGTDYTIGFDTAVNTAAEAIDRLRD 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 581 SASGTkRRVFIVETMGGYCGYLATVTGIAVGADAAYVFEDPFNIHDLkvnVEHMTEKMKTDIQRGLVL--------RNEK 652
Cdd:COG0205 157 TAASH-ERVFVVEVMGRHAGWLALAAGLAGGADLILIPEVPFDLDKL---LEKLKERRKRGKGYSIIVvaegagdeDGEA 232
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 530419267 653 CHDYYTTEFLYNLYSSEGKGV---------FDCRTNVLGHLQQGGAPTPFDRNYGTKLGVKAMLWLSE 711
Cdd:COG0205 233 VLEADTDAFGHVRLGGIGEYLakeieertgIETRVTVLGHLQRGGSPSAFDRVLASRLGAAAVELLLE 300
|
|
| PRK03202 |
PRK03202 |
ATP-dependent 6-phosphofructokinase; |
425-705 |
3.13e-66 |
|
ATP-dependent 6-phosphofructokinase;
Pssm-ID: 235111 [Multi-domain] Cd Length: 320 Bit Score: 223.03 E-value: 3.13e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 425 LAILNVGAPAAGMNAAVRSAVRTGISHGHTVYVVHDGFEGLAKGQVQEVGWHDVAGWLGRGGSMLGTKRT----LPKGQL 500
Cdd:PRK03202 4 IGVLTSGGDAPGMNAAIRAVVRTAISEGLEVYGIYDGYAGLLEGDIVKLDLKSVSDIINRGGTILGSARFpefkDEEGRA 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 501 EsIVENIRIYGIHALLVVGGFEAYEGVLQLVEARgryeelciVMCV-IPATISNNVPGTDFSLGSDTAVNAAMESCDRIK 579
Cdd:PRK03202 84 K-AIENLKKLGIDALVVIGGDGSYMGAKRLTEHG--------IPVIgLPGTIDNDIAGTDYTIGFDTALNTAVEAIDRLR 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 580 QSASgTKRRVFIVETMGGYCGYLATVTGIAVGADAAYVFEDPFNIHDLkvnVEHMTEKMKTDIQRGLVLRNEKCHD--YY 657
Cdd:PRK03202 155 DTAS-SHERVFIVEVMGRHAGDLALHAGIAGGAEVILIPEVPFDIEEL---CAKIKKGRERGKKHAIIVVAEGVMPaeEL 230
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 530419267 658 TTEFlynlyssEGKGVFDCRTNVLGHLQQGGAPTPFDRNYGTKLGVKA 705
Cdd:PRK03202 231 AKEI-------EERTGLETRVTVLGHIQRGGSPTAFDRVLASRMGAHA 271
|
|
| PFK |
cd00363 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
424-748 |
3.05e-60 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to PFK family that includes ATP- and pyrophosphate (PPi)- dependent phosphofructokinases. Some members evolved by gene duplication and thus have a large C-terminal/N-terminal extension comprising a second PFK domain. Generally, ATP-PFKs are allosteric homotetramers, and PPi-PFKs are dimeric and nonallosteric except for plant PPi-PFKs which are allosteric heterotetramers.
Pssm-ID: 238216 [Multi-domain] Cd Length: 338 Bit Score: 207.54 E-value: 3.05e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 424 SLAILNVGAPAAGMNAAVRSAVRTGISHGHTVYVVHDGFEGLAKGQVQEVGWHDVAGWLGRGGSMLGTKRT----LPKGQ 499
Cdd:cd00363 2 KIGVLTSGGDAPGMNAAIRGVVRSAIAEGLEVYGIYEGYAGLVEGDIKELDWESVSDIINRGGTIIGSARCkefrTEEGR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 500 LESIvENIRIYGIHALLVVGGFEAYEGVLQLVE-ARGRYEELCIVMCviPATISNNVPGTDFSLGSDTAVNAAMESCDRI 578
Cdd:cd00363 82 AKAA-ENLKKHGIDALVVIGGDGSYTGADLLTEeWPSKYQGFNVIGL--PGTIDNDIKGTDYTIGFDTALKTIVEAIDRI 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 579 KQSASgTKRRVFIVETMGGYCGYLATVTGIAVGADAAYVFEDPFNihdlKVNVEHMTEKMKTDIQRG----LVLRNEKch 654
Cdd:cd00363 159 RDTAS-SHQRTFVVEVMGRHCGDIALEAGLATGADIIFIPEEPAA----DEWEEEMVDVIKKRRERGkrhgIVIVAEG-- 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 655 dyyTTEFLYNLYSSEG-------KGVFDCRTNVLGHLQQGGAPTPFDRNYGTKLGVKAMLWLSEKLREVyrkgrvfanap 727
Cdd:cd00363 232 ---AIDFIPKPITEKLlaklveeRLGFDTRATVLGHVQRGGTPTAFDRILASRLGAEAVELLLEGTGGT----------- 297
|
330 340
....*....|....*....|.
gi 530419267 728 dSACVIGLKKKAVAFSPVTEL 748
Cdd:cd00363 298 -PVGIQNLNENQVVRHPLTEA 317
|
|
| Bacterial_PFK |
cd00763 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
425-705 |
1.03e-57 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent phosphofructokinases. These are allosrterically regulated homotetramers; the subunits are of about 320 amino acids.
Pssm-ID: 238388 [Multi-domain] Cd Length: 317 Bit Score: 199.94 E-value: 1.03e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 425 LAILNVGAPAAGMNAAVRSAVRTGISHGHTVYVVHDGFEGLAKGQVQEVGWHDVAGWLGRGGSMLGTKR----TLPKGQL 500
Cdd:cd00763 3 IGVLTSGGDAPGMNAAIRGVVRSAIAEGLEVYGIRDGYAGLIAGDIVPLDRYSVSDIINRGGTFLGSARfpefKDEEGQA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 501 ESIvENIRIYGIHALLVVGGFEAYEGVLQLVEARgryeelciVMCV-IPATISNNVPGTDFSLGSDTAVNAAMESCDRIK 579
Cdd:cd00763 83 KAI-EQLKKHGIDALVVIGGDGSYMGAMRLTEHG--------FPCVgLPGTIDNDIPGTDYTIGFDTALNTVVEAIDRIR 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 580 QSASgTKRRVFIVETMGGYCGYLATVTGIAVGADAAYVFEDPFNIHDLKVNVEHMTEKMKtdiQRGLVLRNEkcHDYYTT 659
Cdd:cd00763 154 DTSS-SHQRISVVEVMGRHCGDIALAAGIAGGAEFIVIPEAEFDREEVANRIKAGIERGK---KHAIVVVAE--GVYDVD 227
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 530419267 660 EFLYNLyssEGKGVFDCRTNVLGHLQQGGAPTPFDRNYGTKLGVKA 705
Cdd:cd00763 228 ELAKEI---EEATGFETRATVLGHIQRGGSPTAFDRILASRMGAYA 270
|
|
| PRK14071 |
PRK14071 |
ATP-dependent 6-phosphofructokinase; |
13-382 |
6.54e-53 |
|
ATP-dependent 6-phosphofructokinase;
Pssm-ID: 184487 [Multi-domain] Cd Length: 360 Bit Score: 187.97 E-value: 6.54e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 13 GAGKAIGVLTSGGDAQGMNAAVRAVTR--MGIYvGAKVFLIYEeqrmpyclspsprGRFG--ARPPSwgYEGLveggeNI 88
Cdd:PRK14071 2 GEKKRIGILTSGGDCAGLNAVIRAVVHraRGTY-GWEVIGIRD-------------ATQGlmARPPQ--YIEL-----DL 60
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 89 KQanwlsVSNIIQLGGTIIGSARcK----AFTTREG----RRA---AAYNlvQHGITNLCVIGGDGSLtganifrsewgS 157
Cdd:PRK14071 61 DQ-----VDDLLRMGGTILGTTN-KgdpfAFPMPDGslrdRSQeiiDGYH--SLGLDALIGIGGDGSL-----------A 121
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 158 LLEELVAEGKIsettartyshlNIAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITTTAQSHQRTFVLEVMGRHCGY 237
Cdd:PRK14071 122 ILRRLAQQGGI-----------NLVGIPKTIDNDVGATEVSIGFDTAVNIATEALDRLHFTAASHNRVMILEVMGRDAGH 190
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 238 LALVSALASGADWLFIPEAPPEdgWENfMCERLGETRSRGSRLNIIIIAEGAIDRNGKPIS-------------SSYVKD 304
Cdd:PRK14071 191 IALAAGIAGGADVILIPEIPYT--LEN-VCKKIRERQEEGKNFCLVVVSEAVRTEEGEQVTktqalgedryggiGQYLAE 267
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 530419267 305 LVVQRLGFDTRVTVLGHVQRGGTPSAFDRILSSKMGMEAVMALLEATPDTpacVVTLSGNQSVRLPLMECVQMTKEVQ 382
Cdd:PRK14071 268 QIAERTGAETRVTVLGHIQRGGIPSPRDRLLASAFGVAAVDLIAQGKFDR---MVAWQNRQVVSVPIAEAIATYRAVD 342
|
|
| 6PF1K_euk |
TIGR02478 |
6-phosphofructokinase, eukaryotic type; Members of this family are eukaryotic (with one ... |
9-365 |
7.36e-49 |
|
6-phosphofructokinase, eukaryotic type; Members of this family are eukaryotic (with one exception) ATP-dependent 6-phosphofructokinases (EC 2.7.1.11) in which two tandem copies of the phosphofructokinase are found. Members are found, often including several isozymes, in animals and fungi and in the bacterium Propionibacterium acnes KPA171202 (a human skin commensal).
Pssm-ID: 274152 [Multi-domain] Cd Length: 746 Bit Score: 184.85 E-value: 7.36e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 9 LRASGAGKAIGVLTSGGDAQGMNAAVRAVTRMGIYVGAKVFLIYEeqrmpyclspsprgrfgarppswGYEGLVEGGenI 88
Cdd:TIGR02478 383 VPSEASRLRIAIIHVGAPAGGMNAATRSAVRYALARGHTVIAIHN-----------------------GFSGLARHD--V 437
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 89 KQANWLSVSNIIQLGGTIIGSARCkafTTREGRRAAAYNLVQHGITNLCVIGGDGSLTGANIFRsewgslleelvaegki 168
Cdd:TIGR02478 438 RELTWSDVEGWVGEGGSELGTNRS---LPGDDLGTIAYYFQQHKIDGLIIIGGFEAFEALYQLD---------------- 498
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 169 setTART-YSHLNI--AGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITTTAQ-SHQRTFVLEVMGRHCGYLALVSAL 244
Cdd:TIGR02478 499 ---AAREkYPAFRIpmVVIPATISNNVPGTEYSLGSDTALNEITEYCDNIKQSASaSKRRVFVVETMGGYSGYLATMAGL 575
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 245 ASGADWLFIPEAP-PEDGWEN---FMCERLGETRSRGsrlnIIIIAEGAIdrngKPISSSYVKDLVVQ--RLGFDTRVTV 318
Cdd:TIGR02478 576 ATGADAAYIPEEGiSLKDLQEdieHLKETFAEGRAGK----LILRNEKAS----KVYTTDFIARIISEegKGRFDARTAV 647
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*...
gi 530419267 319 LGHVQRGGTPSAFDRILSSKMGMEAVMALLEATP-----------DTPACVVTLSGNQ 365
Cdd:TIGR02478 648 LGHMQQGGSPSPFDRVRATRLAIRAVDFIEEKIKankhadklsadDTSAVVIGIRGSN 705
|
|
| PRK14071 |
PRK14071 |
ATP-dependent 6-phosphofructokinase; |
427-705 |
1.33e-30 |
|
ATP-dependent 6-phosphofructokinase;
Pssm-ID: 184487 [Multi-domain] Cd Length: 360 Bit Score: 124.03 E-value: 1.33e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 427 ILNVGAPAAGMNAAVRSAVRTGISH-GHTVYVVHDGFEGLAKG--QVQEVGWHDVAGWLGRGGSMLGTKRT-------LP 496
Cdd:PRK14071 9 ILTSGGDCAGLNAVIRAVVHRARGTyGWEVIGIRDATQGLMARppQYIELDLDQVDDLLRMGGTILGTTNKgdpfafpMP 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 497 KGQL----ESIVENIRIYGIHALLVVGGfeayEGVLQLVEargryeELC----IVMCVIPATISNNVPGTDFSLGSDTAV 568
Cdd:PRK14071 89 DGSLrdrsQEIIDGYHSLGLDALIGIGG----DGSLAILR------RLAqqggINLVGIPKTIDNDVGATEVSIGFDTAV 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 569 NAAMESCDRIKQSASgTKRRVFIVETMGGYCGYLATVTGIAVGADAAYVFEDPFNIhdlkvnvEHMTEKMKTDIQRG--- 645
Cdd:PRK14071 159 NIATEALDRLHFTAA-SHNRVMILEVMGRDAGHIALAAGIAGGADVILIPEIPYTL-------ENVCKKIRERQEEGknf 230
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 530419267 646 -LVLRNEKCHDY------YTTEFLYNLYSSEGKGVFD---------CRTNVLGHLQQGGAPTPFDRNYGTKLGVKA 705
Cdd:PRK14071 231 cLVVVSEAVRTEegeqvtKTQALGEDRYGGIGQYLAEqiaertgaeTRVTVLGHIQRGGIPSPRDRLLASAFGVAA 306
|
|
| PTZ00286 |
PTZ00286 |
6-phospho-1-fructokinase; Provisional |
18-289 |
3.06e-26 |
|
6-phospho-1-fructokinase; Provisional
Pssm-ID: 185539 Cd Length: 459 Bit Score: 112.83 E-value: 3.06e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 18 IGVLTSGGDAQGMNAAVRAVTRMGIYVgakvfliYEEQRMpyclspsprgrFGARppsWGYEGLVEggENIKQANWLSVS 97
Cdd:PTZ00286 90 AGIVTCGGLCPGLNVVIRELVMNLINN-------YGVKTI-----------YGAK---YGYKGLYK--EDWIKLDPKDVK 146
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 98 NIIQLGGTIIGSARcKAFTTREgrraAAYNLVQHGITNLCVIGGDGSLTGANifrsewgSLLEELVAEG-KISettarty 176
Cdd:PTZ00286 147 TIHRLGGTILGSSR-GGFDPKV----MVDTLIRHGINILFTLGGDGTHRGAL-------AIYKELRRRKlNIS------- 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 177 shlnIAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITTTAQSHQRTF-VLEVMGRHCGYLALVSALASG-ADWLFIP 254
Cdd:PTZ00286 208 ----VVGIPKTIDNDIPIIDESFGFQTAVEEAQNAIRAAYVEAKSAKNGVgIVKLMGRDSGFIALHASVASAdVNVCLIP 283
|
250 260 270
....*....|....*....|....*....|....*.
gi 530419267 255 EAP-PEDGWENFMCERLGETRSRgsrlnIIIIAEGA 289
Cdd:PTZ00286 284 EFDiPLEGVLEYIEQRLQKKGHC-----VIVVAEGA 314
|
|
| PTZ00286 |
PTZ00286 |
6-phospho-1-fructokinase; Provisional |
417-624 |
5.39e-18 |
|
6-phospho-1-fructokinase; Provisional
Pssm-ID: 185539 Cd Length: 459 Bit Score: 87.79 E-value: 5.39e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 417 PKEKSNFS-----LAILNVGAPAAGMNAAVRSAVRTGIS--HGHTVYVVHDGFEGLAKGQVQEVGWHDVAGWLGRGGSML 489
Cdd:PTZ00286 77 PRKHLYFNpkevkAGIVTCGGLCPGLNVVIRELVMNLINnyGVKTIYGAKYGYKGLYKEDWIKLDPKDVKTIHRLGGTIL 156
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 490 GTKRTlpkGQ-LESIVENIRIYGIHALLVVGGFEAYEGVLQL-VEARGRYEELCIvmCVIPATISNNVPGTDFSLGSDTA 567
Cdd:PTZ00286 157 GSSRG---GFdPKVMVDTLIRHGINILFTLGGDGTHRGALAIyKELRRRKLNISV--VGIPKTIDNDIPIIDESFGFQTA 231
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 530419267 568 VNAAMESCDRIKQSASGTKRRVFIVETMGGYCGYLATVTGIAVG-ADAAYVFEDPFNI 624
Cdd:PTZ00286 232 VEEAQNAIRAAYVEAKSAKNGVGIVKLMGRDSGFIALHASVASAdVNVCLIPEFDIPL 289
|
|
| PRK06830 |
PRK06830 |
ATP-dependent 6-phosphofructokinase; |
77-289 |
2.19e-17 |
|
ATP-dependent 6-phosphofructokinase;
Pssm-ID: 235869 Cd Length: 443 Bit Score: 85.69 E-value: 2.19e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 77 GYEGLV-EGGENIKQANWLSVSNIIQLGGTIIGSARckafttreGRRAAAY---NLVQHGITNLCVIGGDGSLTGANifr 152
Cdd:PRK06830 121 GYQGLIpRYGHDPVELTPEVVADIHEFGGTILGSSR--------GPQDPEEivdTLERMNINILFVIGGDGTLRGAS--- 189
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 153 sewgslleelvaegKISETTARTYSHLNIAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITTTAQSHQRTFVL-EVM 231
Cdd:PRK06830 190 --------------AIAEEIERRGLKISVIGIPKTIDNDINFIQKSFGFETAVEKATEAIRCAHVEANGAPNGIGLvKLM 255
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 232 GRHCGYLALVSALASG-ADWLFIPEAPPE-DGWENFMcERLgETRSRGSRLNIIIIAEGA 289
Cdd:PRK06830 256 GRHSGFIAAYAALASKdVNFVLIPEVPFDlEGPNGLL-AAL-EKRLAERGHAVIVVAEGA 313
|
|
| PLN02564 |
PLN02564 |
6-phosphofructokinase |
95-289 |
7.59e-15 |
|
6-phosphofructokinase
Pssm-ID: 178178 Cd Length: 484 Bit Score: 77.87 E-value: 7.59e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 95 SVSNIIQLGGTIIGSARCKAFTTRegrraAAYNLVQHGITNLCVIGGDGSLTGANifrsewgSLLEELVAEG-KISetta 173
Cdd:PLN02564 144 VVNDIHKRGGTILGTSRGGHDTSK-----IVDSIQDRGINQVYIIGGDGTQKGAS-------VIYEEIRRRGlKVA---- 207
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 174 rtyshlnIAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITTTAQS-HQRTFVLEVMGRHCGYLALVSALAS-GADWL 251
Cdd:PLN02564 208 -------VAGIPKTIDNDIPVIDKSFGFDTAVEEAQRAINAAHVEAESvENGIGLVKLMGRYSGFIAMYATLASrDVDCC 280
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 530419267 252 FIPEAP----PEDGWENFMCERLGETRSRgsrlnIIIIAEGA 289
Cdd:PLN02564 281 LIPESPfyleGKGGLFEFIEKRLKENGHM-----VIVVAEGA 317
|
|
| PRK14072 |
PRK14072 |
diphosphate--fructose-6-phosphate 1-phosphotransferase; |
188-355 |
9.30e-15 |
|
diphosphate--fructose-6-phosphate 1-phosphotransferase;
Pssm-ID: 237600 [Multi-domain] Cd Length: 416 Bit Score: 77.21 E-value: 9.30e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 188 IDNDFCGTDMTIGTDSALHRI----MEV-IDAITTTAQShqRTFVLEVMGRHCGYLALVSALAS-----GADWLFIPEAP 257
Cdd:PRK14072 142 IDNDLPGTDHCPGFGSAAKYIatsvLEAaLDVAAMANTS--KVFILEVMGRHAGWLAAAAALAKqnpddAPHLIYLPERP 219
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 258 PEDgwENFMcERLGETRSRGSRLnIIIIAEGAIDRNGKPISSS-----------------YVKDLVVQRLGFDTRVTVLG 320
Cdd:PRK14072 220 FDE--EKFL-ADVRAIVKRYGYC-VVVVSEGIRDADGKFIAEAglaedafghaqlggvapVLANLIKEKLGKKVHWAVLD 295
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 530419267 321 HVQR--GGTPSAFDR---ILSSKM-------GMEAVMALLEATPDTP 355
Cdd:PRK14072 296 YLQRaaRHIASKTDVeeaYAVGKAaveyalaGKNGVMPAIRRTSDDP 342
|
|
| PLN02884 |
PLN02884 |
6-phosphofructokinase |
413-637 |
1.12e-11 |
|
6-phosphofructokinase
Pssm-ID: 178472 [Multi-domain] Cd Length: 411 Bit Score: 67.53 E-value: 1.12e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 413 HQKPPKEKSNF-----SLAILNVGAPAAGMNAAVRSAVRT----------GISHGHTvyvvhdGF--EGLA-----KGQV 470
Cdd:PLN02884 39 HRAGPRKKIYFepeevKAAIVTCGGLCPGLNDVIRQIVFTleiygvknivGIPFGYR------GFfeKGLSemplsRKVV 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 471 QEVGWHdvagwlgrGGSMLGTKRTLPKgqLESIVENIRIYGIHALLVVGGFEAYEGVLQL-VEARGRYEELCIVmCViPA 549
Cdd:PLN02884 113 QNIHLS--------GGSLLGVSRGGAK--TSDIVDSIEARGINMLFVLGGNGTHAGANAIhNECRKRKMKVSVV-GV-PK 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 550 TISNNVPGTDFSLGSDTAVNAAMESCDRIKQSASGTKRRVFIVETMGGYCGYLATVTGIAVG-ADAAYVFEDPFNIH--- 625
Cdd:PLN02884 181 TIDNDILLMDKTFGFDTAVEEAQRAINSAYIEAHSAYHGIGLVKLMGRSSGFIAMHASLASGqVDICLIPEVPFTLDgpn 260
|
250
....*....|..
gi 530419267 626 DLKVNVEHMTEK 637
Cdd:PLN02884 261 GVLRHLEHLIET 272
|
|
| PLN02884 |
PLN02884 |
6-phosphofructokinase |
75-381 |
1.14e-11 |
|
6-phosphofructokinase
Pssm-ID: 178472 [Multi-domain] Cd Length: 411 Bit Score: 67.53 E-value: 1.14e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 75 SWGYEGLVEggENIKQANwLS---VSNIIQLGGTIIGSARCKAFTTRegrraAAYNLVQHGITNLCVIGGDGSLTGANIf 151
Cdd:PLN02884 91 PFGYRGFFE--KGLSEMP-LSrkvVQNIHLSGGSLLGVSRGGAKTSD-----IVDSIEARGINMLFVLGGNGTHAGANA- 161
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 152 rsewgslleelvaegkISETTARTYSHLNIAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITTTAQSHQRTF-VLEV 230
Cdd:PLN02884 162 ----------------IHNECRKRKMKVSVVGVPKTIDNDILLMDKTFGFDTAVEEAQRAINSAYIEAHSAYHGIgLVKL 225
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 231 MGRHCGYLALVSALASG-ADWLFIPEAPPE-DGWENFM--CERLGETRSRGsrlnIIIIAEGA-IDRNGKPISSSYVKDL 305
Cdd:PLN02884 226 MGRSSGFIAMHASLASGqVDICLIPEVPFTlDGPNGVLrhLEHLIETKGSA----VVCVAEGAgQDLLQKTNATDASGNP 301
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 306 VVQRLGFDTRVTVLGHVQRGGTPS-----------------AFDRILSSKMGMEAVMAlleATPDTPACVVTLSGNQSVR 368
Cdd:PLN02884 302 VLGDIGVHLQQEIKKHFKDIGVPAdvkyidptymiracranASDAILCTVLGQNAVHG---AFAGFSGITVGICNTHYVY 378
|
330
....*....|...
gi 530419267 369 LPLMECVQMTKEV 381
Cdd:PLN02884 379 LPIPEVIAYPRRV 391
|
|
| PRK06830 |
PRK06830 |
ATP-dependent 6-phosphofructokinase; |
436-625 |
2.13e-10 |
|
ATP-dependent 6-phosphofructokinase;
Pssm-ID: 235869 Cd Length: 443 Bit Score: 63.73 E-value: 2.13e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 436 GMNAAVRSAVRTGishgHTVYVVHD------GFEGLakgqVQEVGwHD--------VAGWLGRGGSMLGTKRtlpkGQ-- 499
Cdd:PRK06830 94 GLNDVIRAIVLEL----HHHYGVRRilgiryGYQGL----IPRYG-HDpveltpevVADIHEFGGTILGSSR----GPqd 160
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 500 LESIVENIRIYGIHALLVVGGFEAYEGVLQLV-EARGRYEELCIVmcVIPATISNNVPGTDFSLGSDTAVNAAMESCDRI 578
Cdd:PRK06830 161 PEEIVDTLERMNINILFVIGGDGTLRGASAIAeEIERRGLKISVI--GIPKTIDNDINFIQKSFGFETAVEKATEAIRCA 238
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 530419267 579 KQSASGTKRRVFIVETMGGYCGYLATVTGIAVgADAAYVF--EDPFNIH 625
Cdd:PRK06830 239 HVEANGAPNGIGLVKLMGRHSGFIAAYAALAS-KDVNFVLipEVPFDLE 286
|
|
| PLN02564 |
PLN02564 |
6-phosphofructokinase |
484-622 |
9.40e-10 |
|
6-phosphofructokinase
Pssm-ID: 178178 Cd Length: 484 Bit Score: 61.69 E-value: 9.40e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 484 RGGSMLGTKRtlpKGQ-LESIVENIRIYGIHALLVVGGFEAYEG---VLQLVEARGryeeLCIVMCVIPATISNNVPGTD 559
Cdd:PLN02564 151 RGGTILGTSR---GGHdTSKIVDSIQDRGINQVYIIGGDGTQKGasvIYEEIRRRG----LKVAVAGIPKTIDNDIPVID 223
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 530419267 560 FSLGSDTAVNAAMESCDRIKQSASGTKRRVFIVETMGGYCGYLATVTGIAV-GADAAYVFEDPF 622
Cdd:PLN02564 224 KSFGFDTAVEEAQRAINAAHVEAESVENGIGLVKLMGRYSGFIAMYATLASrDVDCCLIPESPF 287
|
|
| PRK06555 |
PRK06555 |
pyrophosphate--fructose-6-phosphate 1-phosphotransferase; Validated |
77-289 |
1.14e-07 |
|
pyrophosphate--fructose-6-phosphate 1-phosphotransferase; Validated
Pssm-ID: 180620 [Multi-domain] Cd Length: 403 Bit Score: 55.01 E-value: 1.14e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 77 GYEGLVeGGENI-------KQANWLSvsniiQLGGTIIGSARCKAFTT---------REGR---RAAAYNLVQHGITNLC 137
Cdd:PRK06555 44 GYQGLL-LGDSIeitpavrANAGLLH-----RYGGSPIGNSRVKLTNVadcvkrglvKEGEnplKVAAERLAADGVDILH 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 138 VIGGDGSLTGAnifrsewGSLLEELVAEGkisettartYsHLNIAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITT 217
Cdd:PRK06555 118 TIGGDDTNTTA-------ADLAAYLAENG---------Y-DLTVVGLPKTIDNDVVPIRQSLGAWTAAEQGARFFDNVIN 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 218 TAQSHQRTFVL-EVMGRHCGYLALVSALA-----SGADWL---------------FIPEAPPEDGWEnfmCERLGETRSR 276
Cdd:PRK06555 181 EHSANPRMLIIhEVMGRNCGWLTAATARAyrewlDRQEYVpgfglsaerwdihavYLPEMAFDLEAE---AERLKAVMDE 257
|
250
....*....|...
gi 530419267 277 GSRLNiIIIAEGA 289
Cdd:PRK06555 258 VGNVN-IFLSEGA 269
|
|
| PRK14072 |
PRK14072 |
diphosphate--fructose-6-phosphate 1-phosphotransferase; |
431-689 |
8.33e-07 |
|
diphosphate--fructose-6-phosphate 1-phosphotransferase;
Pssm-ID: 237600 [Multi-domain] Cd Length: 416 Bit Score: 52.17 E-value: 8.33e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 431 GAPAAGMNAAVRSAVRTGISHG--HTVYVVHDGFEGLAKGQV---QEVGWHDVAGWLGRGGSMLGTKRTLPKG------Q 499
Cdd:PRK14072 12 GGPTAVINASAAGVIEEARKHKkiGKVYGARNGIIGILDEDLidlSKESDEALAALAHTPSGALGSCRYKLKSleedraE 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 500 LESIVENIRIYGIHALLVVGG---FEAYEGVLQLVEARGrYEELCIVmcvIPATISNNVPGTDFSLGSDTAVN----AAM 572
Cdd:PRK14072 92 YERLLEVFKAHDIGYFFYNGGndsMDTALKVSQLAKKMG-YPIRCIG---IPKTIDNDLPGTDHCPGFGSAAKyiatSVL 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 573 E-SCDrikQSASGTKRRVFIVETMGGYCGYLATVTGIA-----VGADAAYVFEDPFNIHDLKVNVEHMTEKMKtdiqRGL 646
Cdd:PRK14072 168 EaALD---VAAMANTSKVFILEVMGRHAGWLAAAAALAkqnpdDAPHLIYLPERPFDEEKFLADVRAIVKRYG----YCV 240
|
250 260 270 280
....*....|....*....|....*....|....*....|....*
gi 530419267 647 VLRNEKCHDyytteflynlysSEGKGVFD--CRTNVLGHLQQGGA 689
Cdd:PRK14072 241 VVVSEGIRD------------ADGKFIAEagLAEDAFGHAQLGGV 273
|
|
| PTZ00287 |
PTZ00287 |
6-phosphofructokinase; Provisional |
18-291 |
6.48e-06 |
|
6-phosphofructokinase; Provisional
Pssm-ID: 240345 [Multi-domain] Cd Length: 1419 Bit Score: 50.04 E-value: 6.48e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 18 IGVLTSGGDAQGMNAAVRavtrmGIYVGAKvfliyeeqrmpyclspsprgRFGARPPSWGYEGLVEGgenIKQANWLSVS 97
Cdd:PTZ00287 180 IGIILSGGPAPGGHNVIS-----GIYDYAK--------------------RYNEQSQVIGFLGGIDG---LYSKNYVTIT 231
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 98 NII-----QLGG-TIIGSARCKafTTREGRRAAAYNLVQH-GITNLCVIGGDGSLTGAnifrsewgSLLEELVAEGKISe 170
Cdd:PTZ00287 232 DSLmnrfrNLGGfNMLWSGRGK--VRNKDDLIAIENIVAKlKLNGLVIIGGDGSNSNA--------ALISEYFAERQIP- 300
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 171 ttartyshLNIAGLVGSIDNDFC--GTDMTIGTDSALHRIMEVIDAITTTAQS-HQRTFVLEVMGRHCGYLALVSALASG 247
Cdd:PTZ00287 301 --------ISIIGIPKTIDGDLKseAIEISFGFDTATKTYSEVIGNLCTDVKTgHNVYHVVRVMGRSASHVVLECALQTR 372
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 530419267 248 ADWLFIPEAPPEDGWE---------NFMCERlgetRSRGSRLNIIIIAEGAID 291
Cdd:PTZ00287 373 PNIVLIGEEVEKENLSlkdivsnivNTILKR----RSLNKNYGVILIPEGLIE 421
|
|
| PTZ00468 |
PTZ00468 |
phosphofructokinase family protein; Provisional |
96-291 |
3.44e-04 |
|
phosphofructokinase family protein; Provisional
Pssm-ID: 185647 [Multi-domain] Cd Length: 1328 Bit Score: 44.19 E-value: 3.44e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 96 VSNIIQLGG-TIIGSARCKaFTTREGRRAAAYNLVQHGITNLCVIGGDGSLTGANIfrsewgslleelvaegkISETTAR 174
Cdd:PTZ00468 160 INGILNQGGfNIICSGRHK-IETEEQMRASLEICEKLKLHGLVVIGGDDSNTNAAV-----------------LAEYFKR 221
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530419267 175 TYSHLNIAGLVGSIDNDFCG--TDMTIGTDSALHRIMEVIDAITTTAQSHQ-RTFVLEVMGRHCGYLALVSALASGADWL 251
Cdd:PTZ00468 222 NSSSTVVVGCPKTIDGDLKNevIETSFGYDTAVKTYSEQIGSIMDAIKTEGyGYYFVRLMGRSASHITLECGLQTRANMI 301
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 530419267 252 FIPEAPPEDGWE-----NFMCERLGETRSRGSRLNIIIIAEGAID 291
Cdd:PTZ00468 302 LIGEEIKEENRSlmsivDEIVEMILKRDSLGKKHGIVLLPEGLIE 346
|
|
| |
