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Conserved domains on  [gi|530367936|ref|XP_005264537|]
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ATP-binding cassette sub-family G member 5 isoform X5 [Homo sapiens]

Protein Classification

ABCG_White domain-containing protein( domain architecture ID 12931634)

ABCG_White domain-containing protein

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
ABCG_White cd03234
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ...
50-275 1.39e-112

White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.


:

Pssm-ID: 213201 [Multi-domain]  Cd Length: 226  Bit Score: 334.24  E-value: 1.39e-112
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  50 RVRPWWDITSCRQQW--TRQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGTFLGEVYVNGRALRREQFQD 127
Cdd:cd03234    2 RVLPWWDVGLKAKNWnkYARILNDVSLHVESGQVMAILGSSGSGKTTLLDAISGRVEGGGTTSGQILFNGQPRKPDQFQK 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 128 CFSYVLQSDTLLSSLTVRETLHYTALLAIRRGNPGSFQKKVEAVMaelSLSHVADRLIGNYSLGGISTGERRRVSIAAQL 207
Cdd:cd03234   82 CVAYVRQDDILLPGLTVRETLTYTAILRLPRKSSDAIRKKRVEDV---LLRDLALTRIGGNLVKGISGGERRRVSIAVQL 158
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 530367936 208 LQDPKVMLFDEPTTGLDCMTANQIVVLLVELARRNRIVVLTIHQPRSELFQLFDKIAILSFGELIFCG 275
Cdd:cd03234  159 LWDPKVLILDEPTSGLDSFTALNLVSTLSQLARRNRIVILTIHQPRSDLFRLFDRILLLSSGEIVYSG 226
3a01204 super family cl36780
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ...
60-548 5.47e-98

The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]


The actual alignment was detected with superfamily member TIGR00955:

Pssm-ID: 273361 [Multi-domain]  Cd Length: 617  Bit Score: 310.06  E-value: 5.47e-98
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936   60 CRQQWTRQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGTFLGEVYVNGRALRREQFQDCFSYVLQSDTLL 139
Cdd:TIGR00955  32 CRERPRKHLLKNVSGVAKPGELLAVMGSSGAGKTTLMNALAFRSPKGVKGSGSVLLNGMPIDAKEMRAISAYVQQDDLFI 111
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  140 SSLTVRETLHYTALLAIRRGNPGSfQKK--VEAVMAELSLSHVADRLIGNYS-LGGISTGERRRVSIAAQLLQDPKVMLF 216
Cdd:TIGR00955 112 PTLTVREHLMFQAHLRMPRRVTKK-EKRerVDEVLQALGLRKCANTRIGVPGrVKGLSGGERKRLAFASELLTDPPLLFC 190
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  217 DEPTTGLDCMTANQIVVLLVELARRNRIVVLTIHQPRSELFQLFDKIAILSFGELIFCGTPAEMLDFFNDCGYPCPEHSN 296
Cdd:TIGR00955 191 DEPTSGLDSFMAYSVVQVLKGLAQKGKTIICTIHQPSSELFELFDKIILMAEGRVAYLGSPDQAVPFFSDLGHPCPENYN 270
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  297 PFDFYMDLTSVDtqsKEREIETSKRVQMIESAYKKSAICHKTLKNIeRMKHLKTLPMV-----PFKTKDSPGVFSKLGVL 371
Cdd:TIGR00955 271 PADFYVQVLAVI---PGSENESRERIEKICDSFAVSDIGRDMLVNT-NLWSGKAGGLVkdsenMEGIGYNASWWTQFYAL 346
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  372 LRRVTRNLVRNKLAVITRLLQNLIMGLF--LLFFVLRVRSnvlKGaIQDRVGLLYQFVGATPYTGMLNAVNLFPVLRAVS 449
Cdd:TIGR00955 347 LKRSWLSVLRDPLLLKVRLIQTMMTAILigLIYLGQGLTQ---KG-VQNINGALFLFLTNMTFQNVFPVINVFTAELPVF 422
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  450 DQESQDGLYQKWQMMLAYALHVLPFSVVATMIFSSVCYWTLGLHPEVARFGYFSAALLAPHLIGEFLTLVLLGIVQNPNI 529
Cdd:TIGR00955 423 LRETRSGLYRVSAYFLAKTIAELPLFIILPALFTSITYWMIGLRSGATHFLTFLFLVTLVANVATSFGYLISCAFSSTSM 502
                         490
                  ....*....|....*....
gi 530367936  530 VNSVVALLSIAgVLVGSGF 548
Cdd:TIGR00955 503 ALTVGPPFVIP-FLLFGGF 520
 
Name Accession Description Interval E-value
ABCG_White cd03234
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ...
50-275 1.39e-112

White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.


Pssm-ID: 213201 [Multi-domain]  Cd Length: 226  Bit Score: 334.24  E-value: 1.39e-112
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  50 RVRPWWDITSCRQQW--TRQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGTFLGEVYVNGRALRREQFQD 127
Cdd:cd03234    2 RVLPWWDVGLKAKNWnkYARILNDVSLHVESGQVMAILGSSGSGKTTLLDAISGRVEGGGTTSGQILFNGQPRKPDQFQK 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 128 CFSYVLQSDTLLSSLTVRETLHYTALLAIRRGNPGSFQKKVEAVMaelSLSHVADRLIGNYSLGGISTGERRRVSIAAQL 207
Cdd:cd03234   82 CVAYVRQDDILLPGLTVRETLTYTAILRLPRKSSDAIRKKRVEDV---LLRDLALTRIGGNLVKGISGGERRRVSIAVQL 158
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 530367936 208 LQDPKVMLFDEPTTGLDCMTANQIVVLLVELARRNRIVVLTIHQPRSELFQLFDKIAILSFGELIFCG 275
Cdd:cd03234  159 LWDPKVLILDEPTSGLDSFTALNLVSTLSQLARRNRIVILTIHQPRSDLFRLFDRILLLSSGEIVYSG 226
3a01204 TIGR00955
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ...
60-548 5.47e-98

The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273361 [Multi-domain]  Cd Length: 617  Bit Score: 310.06  E-value: 5.47e-98
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936   60 CRQQWTRQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGTFLGEVYVNGRALRREQFQDCFSYVLQSDTLL 139
Cdd:TIGR00955  32 CRERPRKHLLKNVSGVAKPGELLAVMGSSGAGKTTLMNALAFRSPKGVKGSGSVLLNGMPIDAKEMRAISAYVQQDDLFI 111
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  140 SSLTVRETLHYTALLAIRRGNPGSfQKK--VEAVMAELSLSHVADRLIGNYS-LGGISTGERRRVSIAAQLLQDPKVMLF 216
Cdd:TIGR00955 112 PTLTVREHLMFQAHLRMPRRVTKK-EKRerVDEVLQALGLRKCANTRIGVPGrVKGLSGGERKRLAFASELLTDPPLLFC 190
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  217 DEPTTGLDCMTANQIVVLLVELARRNRIVVLTIHQPRSELFQLFDKIAILSFGELIFCGTPAEMLDFFNDCGYPCPEHSN 296
Cdd:TIGR00955 191 DEPTSGLDSFMAYSVVQVLKGLAQKGKTIICTIHQPSSELFELFDKIILMAEGRVAYLGSPDQAVPFFSDLGHPCPENYN 270
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  297 PFDFYMDLTSVDtqsKEREIETSKRVQMIESAYKKSAICHKTLKNIeRMKHLKTLPMV-----PFKTKDSPGVFSKLGVL 371
Cdd:TIGR00955 271 PADFYVQVLAVI---PGSENESRERIEKICDSFAVSDIGRDMLVNT-NLWSGKAGGLVkdsenMEGIGYNASWWTQFYAL 346
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  372 LRRVTRNLVRNKLAVITRLLQNLIMGLF--LLFFVLRVRSnvlKGaIQDRVGLLYQFVGATPYTGMLNAVNLFPVLRAVS 449
Cdd:TIGR00955 347 LKRSWLSVLRDPLLLKVRLIQTMMTAILigLIYLGQGLTQ---KG-VQNINGALFLFLTNMTFQNVFPVINVFTAELPVF 422
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  450 DQESQDGLYQKWQMMLAYALHVLPFSVVATMIFSSVCYWTLGLHPEVARFGYFSAALLAPHLIGEFLTLVLLGIVQNPNI 529
Cdd:TIGR00955 423 LRETRSGLYRVSAYFLAKTIAELPLFIILPALFTSITYWMIGLRSGATHFLTFLFLVTLVANVATSFGYLISCAFSSTSM 502
                         490
                  ....*....|....*....
gi 530367936  530 VNSVVALLSIAgVLVGSGF 548
Cdd:TIGR00955 503 ALTVGPPFVIP-FLLFGGF 520
PLN03211 PLN03211
ABC transporter G-25; Provisional
61-552 1.14e-62

ABC transporter G-25; Provisional


Pssm-ID: 215634 [Multi-domain]  Cd Length: 659  Bit Score: 217.44  E-value: 1.14e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  61 RQQWTRQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLgRAGTFLGEVYVNGRALRREQFQDCfSYVLQSDTLLS 140
Cdd:PLN03211  76 RQIQERTILNGVTGMASPGEILAVLGPSGSGKSTLLNALAGRI-QGNNFTGTILANNRKPTKQILKRT-GFVTQDDILYP 153
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 141 SLTVRETLHYTALLAIrrgnPGSFQKKV-----EAVMAELSLSHVADRLIGNYSLGGISTGERRRVSIAAQLLQDPKVML 215
Cdd:PLN03211 154 HLTVRETLVFCSLLRL----PKSLTKQEkilvaESVISELGLTKCENTIIGNSFIRGISGGERKRVSIAHEMLINPSLLI 229
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 216 FDEPTTGLDCMTANQIVVLLVELARRNRIVVLTIHQPRSELFQLFDKIAILSFGELIFCGTPAEMLDFFNDCGYPCPEHS 295
Cdd:PLN03211 230 LDEPTSGLDATAAYRLVLTLGSLAQKGKTIVTSMHQPSSRVYQMFDSVLVLSEGRCLFFGKGSDAMAYFESVGFSPSFPM 309
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 296 NPFDFYMDLTSVDTQS---KEREIETSKrvQMIESAYkkSAICHKTLKNIERMKHLKTLP---MVPFKTKDSPGV----- 364
Cdd:PLN03211 310 NPADFLLDLANGVCQTdgvSEREKPNVK--QSLVASY--NTLLAPKVKAAIEMSHFPQANarfVGSASTKEHRSSdrisi 385
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 365 ---FSKLGVLLRRV---TRNLVRNKLAVITRLLQNLIMGLFLLFFVLRvrsnvlkgAIQDRVGLLY---QFVGATPYTgm 435
Cdd:PLN03211 386 stwFNQFSILLQRSlkeRKHESFNTLRVFQVIAAALLAGLMWWHSDFR--------DVQDRLGLLFfisIFWGVFPSF-- 455
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 436 lNAVNLFPVLRAVSDQESQDGLYQKWQMMLAYALHVLPFSVVATMIFSSVCYWTLGLHPEVARFGYFSAALLAPHLIGEF 515
Cdd:PLN03211 456 -NSVFVFPQERAIFVKERASGMYTLSSYFMARIVGDLPMELILPTIFLTVTYWMAGLKPELGAFLLTLLVLLGYVLVSQG 534
                        490       500       510
                 ....*....|....*....|....*....|....*..
gi 530367936 516 LTLVLLGIVQNPNIVNSVVALLSIAGVLVGSGFLRQL 552
Cdd:PLN03211 535 LGLALGAAIMDAKKASTIVTVTMLAFVLTGGFYVHKL 571
CcmA COG1131
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
66-282 9.46e-51

ABC-type multidrug transport system, ATPase component [Defense mechanisms];


Pssm-ID: 440746 [Multi-domain]  Cd Length: 236  Bit Score: 174.10  E-value: 9.46e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  66 RQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLgRAGTflGEVYVNGRALRRE--QFQDCFSYVLQSDTLLSSLT 143
Cdd:COG1131   13 KTALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLL-RPTS--GEVRVLGEDVARDpaEVRRRIGYVPQEPALYPDLT 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 144 VRETLHYTALLairRGNPGS-FQKKVEAVMAELSLSHVADRLIGNYSLGgistgERRRVSIAAQLLQDPKVMLFDEPTTG 222
Cdd:COG1131   90 VRENLRFFARL---YGLPRKeARERIDELLELFGLTDAADRKVGTLSGG-----MKQRLGLALALLHDPELLILDEPTSG 161
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 223 LDCMTANQIVVLLVELARRNRIVVLTIHQPrSELFQLFDKIAILSFGELIFCGTPAEMLD 282
Cdd:COG1131  162 LDPEARRELWELLRELAAEGKTVLLSTHYL-EEAERLCDRVAIIDKGRIVADGTPDELKA 220
ABC_tran pfam00005
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...
69-221 4.19e-32

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.


Pssm-ID: 394964 [Multi-domain]  Cd Length: 150  Bit Score: 120.83  E-value: 4.19e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936   69 LKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGtflGEVYVNGRALR---REQFQDCFSYVLQSDTLLSSLTVR 145
Cdd:pfam00005   1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTE---GTILLDGQDLTddeRKSLRKEIGYVFQDPQLFPRLTVR 77
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 530367936  146 ETLHYTALLAIRRGNPgsFQKKVEAVMAELSLSHVADRLIGNYSlGGISTGERRRVSIAAQLLQDPKVMLFDEPTT 221
Cdd:pfam00005  78 ENLRLGLLLKGLSKRE--KDARAEEALEKLGLGDLADRPVGERP-GTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150
LPS_export_lptB TIGR04406
LPS export ABC transporter ATP-binding protein; Members of this fmaily are LptB, the ...
66-281 1.36e-28

LPS export ABC transporter ATP-binding protein; Members of this fmaily are LptB, the ATP-binding cassette protein of an ABC transporter involved in lipopolysaccharide export. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]


Pssm-ID: 275199 [Multi-domain]  Cd Length: 239  Bit Score: 113.91  E-value: 1.36e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936   66 RQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGrLGRAGTflGEVYVNGRALRR----EQFQDCFSYVLQSDTLLSS 141
Cdd:TIGR04406  14 RKVVNDVSLSVKSGEIVGLLGPNGAGKTTSFYMIVG-LVRPDA--GKILIDGQDITHlpmhERARLGIGYLPQEASIFRK 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  142 LTVRETLhyTALLAIR-RGNPGSFQKKVEAVMAELSLSHVADRLigNYSLGGistGERRRVSIAAQLLQDPKVMLFDEPT 220
Cdd:TIGR04406  91 LTVEENI--MAVLEIRkDLDRAEREERLEALLEEFQISHLRDNK--AMSLSG---GERRRVEIARALATNPKFILLDEPF 163
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 530367936  221 TGLDCMTANQIVVLLVELARRNRIVVLTIHQPRsELFQLFDKIAILSFGELIFCGTPAEML 281
Cdd:TIGR04406 164 AGVDPIAVGDIKKIIKHLKERGIGVLITDHNVR-ETLDICDRAYIISDGKVLAEGTPAEIV 223
hmuV PRK13548
hemin importer ATP-binding subunit; Provisional
66-281 1.25e-24

hemin importer ATP-binding subunit; Provisional


Pssm-ID: 237422 [Multi-domain]  Cd Length: 258  Bit Score: 102.93  E-value: 1.25e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  66 RQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLgRAGTflGEVYVNGRAL----------RREqfqdcfsyVL-Q 134
Cdd:PRK13548  15 RTLLDDVSLTLRPGEVVAILGPNGAGKSTLLRALSGEL-SPDS--GEVRLNGRPLadwspaelarRRA--------VLpQ 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 135 SDTLLSSLTVRETLhytAL-LAIRRGNPGSFQKKVEAVMAELSLSHVADRLignY-SLGGistGERRRVSIA---AQLLQ 209
Cdd:PRK13548  84 HSSLSFPFTVEEVV---AMgRAPHGLSRAEDDALVAAALAQVDLAHLAGRD---YpQLSG---GEQQRVQLArvlAQLWE 154
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 210 D---PKVMLFDEPTTGLDcmTANQIVVL--LVELARRNR---IVVLtiHqprsELFQ--LF-DKIAILSFGELIFCGTPA 278
Cdd:PRK13548 155 PdgpPRWLLLDEPTSALD--LAHQHHVLrlARQLAHERGlavIVVL--H----DLNLaaRYaDRIVLLHQGRLVADGTPA 226

                 ...
gi 530367936 279 EML 281
Cdd:PRK13548 227 EVL 229
ABC2_membrane pfam01061
ABC-2 type transporter;
371-549 7.27e-16

ABC-2 type transporter;


Pssm-ID: 426023 [Multi-domain]  Cd Length: 204  Bit Score: 76.54  E-value: 7.27e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  371 LLRRVTRNLVRNKLAVITRLLQNLIMGLFL--LFFVLRvrsnvLKGAIQDRVGLLYQFVGATPYTGMLNAVNLFPVLRAV 448
Cdd:pfam01061   1 LLKREFLRRWRDPSLGLWRLIQPILMALIFgtLFGNLG-----NQQGGLNRPGLLFFSILFNAFSALSGISPVFEKERGV 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  449 SDQESQDGLYQKWQMMLAYALHVLPFSVVATMIFSSVCYWTLGLHPEVARFGYFSAALLAPHLIGEFLTLVLLGIVQNPN 528
Cdd:pfam01061  76 LYRELASPLYSPSAYVLAKILSELPLSLLQSLIFLLIVYFMVGLPPSAGRFFLFLLVLLLTALAASSLGLFISALAPSFE 155
                         170       180
                  ....*....|....*....|.
gi 530367936  529 IVNSVVALLSIAGVLVgSGFL 549
Cdd:pfam01061 156 DASQLGPLVLLPLLLL-SGFF 175
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
71-279 2.70e-13

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 72.85  E-value: 2.70e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  71 DVSLYVESGQIMCILGSSGSGKTT-------LLDAMSGR---LGRagtflgEVYVNGRALRREqfqdcFSYVLQSDTLLS 140
Cdd:NF033858 284 HVSFRIRRGEIFGFLGSNGCGKSTtmkmltgLLPASEGEawlFGQ------PVDAGDIATRRR-----VGYMSQAFSLYG 352
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 141 SLTVRE--TLHytALLairrgnpgsFQ-------KKVEAVMAELSLSHVADRLIGNYSLGgistgERRRVSIAAQLLQDP 211
Cdd:NF033858 353 ELTVRQnlELH--ARL---------FHlpaaeiaARVAEMLERFDLADVADALPDSLPLG-----IRQRLSLAVAVIHKP 416
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 530367936 212 KVMLFDEPTTGLDCMTANQIVVLLVELARRNRIvvlTI----HqprselfqlF-------DKIAILSFGELIFCGTPAE 279
Cdd:NF033858 417 ELLILDEPTSGVDPVARDMFWRLLIELSREDGV---TIfistH---------FmneaercDRISLMHAGRVLASDTPAA 483
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
165-280 2.64e-08

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 55.90  E-value: 2.64e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 165 QKKVEAVMAELSLSHVADRLIGNYSlGGIstgeRRRVSIAAQLLQDPKVMLFDEPTTGLDCMTANQIVVLLVELARRNRI 244
Cdd:NF000106 122 RARADELLERFSLTEAAGRAAAKYS-GGM----RRRLDLAASMIGRPAVLYLDEPTTGLDPRTRNEVWDEVRSMVRDGAT 196
                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 530367936 245 VVLTIhQPRSELFQLFDKIAILSFGELIFCGTPAEM 280
Cdd:NF000106 197 VLLTT-QYMEEAEQLAHELTVIDRGRVIADGKVDEL 231
GguA NF040905
sugar ABC transporter ATP-binding protein;
62-272 7.02e-06

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 48.63  E-value: 7.02e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  62 QQWTRQILKDVSLYVESGQIMCILGSSGSGKTTLldAMSgRLGRA-GTFL-GEVYVNGRALR----REQFQDCFSYV--- 132
Cdd:NF040905 269 LHPERKVVDDVSLNVRRGEIVGIAGLMGAGRTEL--AMS-VFGRSyGRNIsGTVFKDGKEVDvstvSDAIDAGLAYVted 345
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 133 -----------LQSDTLLSSLT----------VRETL---HYTALLAIRrgNPGSFQKkveavmaelslshvadrlIGNy 188
Cdd:NF040905 346 rkgyglnliddIKRNITLANLGkvsrrgvideNEEIKvaeEYRKKMNIK--TPSVFQK------------------VGN- 404
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 189 slggISTGERRRVSIAAQLLQDPKVMLFDEPTTGLDCMTANQIVVLLVELARRNRIVVLtIHQPRSELFQLFDKIAILSF 268
Cdd:NF040905 405 ----LSGGNQQKVVLSKWLFTDPDVLILDEPTRGIDVGAKYEIYTIINELAAEGKGVIV-ISSELPELLGMCDRIYVMNE 479

                 ....
gi 530367936 269 GELI 272
Cdd:NF040905 480 GRIT 483
GguA NF040905
sugar ABC transporter ATP-binding protein;
69-121 6.25e-04

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 42.47  E-value: 6.25e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 530367936  69 LKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGrAGTFLGEVYVNGRALR 121
Cdd:NF040905  17 LDDVNLSVREGEIHALCGENGAGKSTLMKVLSGVYP-HGSYEGEILFDGEVCR 68
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
78-127 7.47e-04

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 40.05  E-value: 7.47e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 530367936    78 SGQIMCILGSSGSGKTTLLDAMSGRLGRAGTflGEVYVNGRALRREQFQD 127
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARELGPPGG--GVIYIDGEDILEEVLDQ 48
 
Name Accession Description Interval E-value
ABCG_White cd03234
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ...
50-275 1.39e-112

White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.


Pssm-ID: 213201 [Multi-domain]  Cd Length: 226  Bit Score: 334.24  E-value: 1.39e-112
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  50 RVRPWWDITSCRQQW--TRQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGTFLGEVYVNGRALRREQFQD 127
Cdd:cd03234    2 RVLPWWDVGLKAKNWnkYARILNDVSLHVESGQVMAILGSSGSGKTTLLDAISGRVEGGGTTSGQILFNGQPRKPDQFQK 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 128 CFSYVLQSDTLLSSLTVRETLHYTALLAIRRGNPGSFQKKVEAVMaelSLSHVADRLIGNYSLGGISTGERRRVSIAAQL 207
Cdd:cd03234   82 CVAYVRQDDILLPGLTVRETLTYTAILRLPRKSSDAIRKKRVEDV---LLRDLALTRIGGNLVKGISGGERRRVSIAVQL 158
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 530367936 208 LQDPKVMLFDEPTTGLDCMTANQIVVLLVELARRNRIVVLTIHQPRSELFQLFDKIAILSFGELIFCG 275
Cdd:cd03234  159 LWDPKVLILDEPTSGLDSFTALNLVSTLSQLARRNRIVILTIHQPRSDLFRLFDRILLLSSGEIVYSG 226
3a01204 TIGR00955
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ...
60-548 5.47e-98

The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273361 [Multi-domain]  Cd Length: 617  Bit Score: 310.06  E-value: 5.47e-98
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936   60 CRQQWTRQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGTFLGEVYVNGRALRREQFQDCFSYVLQSDTLL 139
Cdd:TIGR00955  32 CRERPRKHLLKNVSGVAKPGELLAVMGSSGAGKTTLMNALAFRSPKGVKGSGSVLLNGMPIDAKEMRAISAYVQQDDLFI 111
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  140 SSLTVRETLHYTALLAIRRGNPGSfQKK--VEAVMAELSLSHVADRLIGNYS-LGGISTGERRRVSIAAQLLQDPKVMLF 216
Cdd:TIGR00955 112 PTLTVREHLMFQAHLRMPRRVTKK-EKRerVDEVLQALGLRKCANTRIGVPGrVKGLSGGERKRLAFASELLTDPPLLFC 190
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  217 DEPTTGLDCMTANQIVVLLVELARRNRIVVLTIHQPRSELFQLFDKIAILSFGELIFCGTPAEMLDFFNDCGYPCPEHSN 296
Cdd:TIGR00955 191 DEPTSGLDSFMAYSVVQVLKGLAQKGKTIICTIHQPSSELFELFDKIILMAEGRVAYLGSPDQAVPFFSDLGHPCPENYN 270
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  297 PFDFYMDLTSVDtqsKEREIETSKRVQMIESAYKKSAICHKTLKNIeRMKHLKTLPMV-----PFKTKDSPGVFSKLGVL 371
Cdd:TIGR00955 271 PADFYVQVLAVI---PGSENESRERIEKICDSFAVSDIGRDMLVNT-NLWSGKAGGLVkdsenMEGIGYNASWWTQFYAL 346
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  372 LRRVTRNLVRNKLAVITRLLQNLIMGLF--LLFFVLRVRSnvlKGaIQDRVGLLYQFVGATPYTGMLNAVNLFPVLRAVS 449
Cdd:TIGR00955 347 LKRSWLSVLRDPLLLKVRLIQTMMTAILigLIYLGQGLTQ---KG-VQNINGALFLFLTNMTFQNVFPVINVFTAELPVF 422
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  450 DQESQDGLYQKWQMMLAYALHVLPFSVVATMIFSSVCYWTLGLHPEVARFGYFSAALLAPHLIGEFLTLVLLGIVQNPNI 529
Cdd:TIGR00955 423 LRETRSGLYRVSAYFLAKTIAELPLFIILPALFTSITYWMIGLRSGATHFLTFLFLVTLVANVATSFGYLISCAFSSTSM 502
                         490
                  ....*....|....*....
gi 530367936  530 VNSVVALLSIAgVLVGSGF 548
Cdd:TIGR00955 503 ALTVGPPFVIP-FLLFGGF 520
ABCG_EPDR cd03213
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ...
50-275 2.96e-64

Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.


Pssm-ID: 213180 [Multi-domain]  Cd Length: 194  Bit Score: 208.17  E-value: 2.96e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  50 RVRPWWD-----ITSCRQQWTRQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGTfLGEVYVNGRALRREQ 124
Cdd:cd03213    1 GVTLSFRnltvtVKSSPSKSGKQLLKNVSGKAKPGELTAIMGPSGAGKSTLLNALAGRRTGLGV-SGEVLINGRPLDKRS 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 125 FQDCFSYVLQSDTLLSSLTVRETLHYTALLAirrgnpgsfqkkveavmaelslshvadrlignyslgGISTGERRRVSIA 204
Cdd:cd03213   80 FRKIIGYVPQDDILHPTLTVRETLMFAAKLR------------------------------------GLSGGERKRVSIA 123
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 530367936 205 AQLLQDPKVMLFDEPTTGLDCMTANQIVVLLVELARRNRIVVLTIHQPRSELFQLFDKIAILSFGELIFCG 275
Cdd:cd03213  124 LELVSNPSLLFLDEPTSGLDSSSALQVMSLLRRLADTGRTIICSIHQPSSEIFELFDKLLLLSQGRVIYFG 194
PLN03211 PLN03211
ABC transporter G-25; Provisional
61-552 1.14e-62

ABC transporter G-25; Provisional


Pssm-ID: 215634 [Multi-domain]  Cd Length: 659  Bit Score: 217.44  E-value: 1.14e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  61 RQQWTRQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLgRAGTFLGEVYVNGRALRREQFQDCfSYVLQSDTLLS 140
Cdd:PLN03211  76 RQIQERTILNGVTGMASPGEILAVLGPSGSGKSTLLNALAGRI-QGNNFTGTILANNRKPTKQILKRT-GFVTQDDILYP 153
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 141 SLTVRETLHYTALLAIrrgnPGSFQKKV-----EAVMAELSLSHVADRLIGNYSLGGISTGERRRVSIAAQLLQDPKVML 215
Cdd:PLN03211 154 HLTVRETLVFCSLLRL----PKSLTKQEkilvaESVISELGLTKCENTIIGNSFIRGISGGERKRVSIAHEMLINPSLLI 229
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 216 FDEPTTGLDCMTANQIVVLLVELARRNRIVVLTIHQPRSELFQLFDKIAILSFGELIFCGTPAEMLDFFNDCGYPCPEHS 295
Cdd:PLN03211 230 LDEPTSGLDATAAYRLVLTLGSLAQKGKTIVTSMHQPSSRVYQMFDSVLVLSEGRCLFFGKGSDAMAYFESVGFSPSFPM 309
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 296 NPFDFYMDLTSVDTQS---KEREIETSKrvQMIESAYkkSAICHKTLKNIERMKHLKTLP---MVPFKTKDSPGV----- 364
Cdd:PLN03211 310 NPADFLLDLANGVCQTdgvSEREKPNVK--QSLVASY--NTLLAPKVKAAIEMSHFPQANarfVGSASTKEHRSSdrisi 385
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 365 ---FSKLGVLLRRV---TRNLVRNKLAVITRLLQNLIMGLFLLFFVLRvrsnvlkgAIQDRVGLLY---QFVGATPYTgm 435
Cdd:PLN03211 386 stwFNQFSILLQRSlkeRKHESFNTLRVFQVIAAALLAGLMWWHSDFR--------DVQDRLGLLFfisIFWGVFPSF-- 455
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 436 lNAVNLFPVLRAVSDQESQDGLYQKWQMMLAYALHVLPFSVVATMIFSSVCYWTLGLHPEVARFGYFSAALLAPHLIGEF 515
Cdd:PLN03211 456 -NSVFVFPQERAIFVKERASGMYTLSSYFMARIVGDLPMELILPTIFLTVTYWMAGLKPELGAFLLTLLVLLGYVLVSQG 534
                        490       500       510
                 ....*....|....*....|....*....|....*..
gi 530367936 516 LTLVLLGIVQNPNIVNSVVALLSIAGVLVGSGFLRQL 552
Cdd:PLN03211 535 LGLALGAAIMDAKKASTIVTVTMLAFVLTGGFYVHKL 571
CcmA COG1131
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
66-282 9.46e-51

ABC-type multidrug transport system, ATPase component [Defense mechanisms];


Pssm-ID: 440746 [Multi-domain]  Cd Length: 236  Bit Score: 174.10  E-value: 9.46e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  66 RQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLgRAGTflGEVYVNGRALRRE--QFQDCFSYVLQSDTLLSSLT 143
Cdd:COG1131   13 KTALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLL-RPTS--GEVRVLGEDVARDpaEVRRRIGYVPQEPALYPDLT 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 144 VRETLHYTALLairRGNPGS-FQKKVEAVMAELSLSHVADRLIGNYSLGgistgERRRVSIAAQLLQDPKVMLFDEPTTG 222
Cdd:COG1131   90 VRENLRFFARL---YGLPRKeARERIDELLELFGLTDAADRKVGTLSGG-----MKQRLGLALALLHDPELLILDEPTSG 161
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 223 LDCMTANQIVVLLVELARRNRIVVLTIHQPrSELFQLFDKIAILSFGELIFCGTPAEMLD 282
Cdd:COG1131  162 LDPEARRELWELLRELAAEGKTVLLSTHYL-EEAERLCDRVAIIDKGRIVADGTPDELKA 220
3a01205 TIGR00956
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
61-511 1.44e-48

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273362 [Multi-domain]  Cd Length: 1394  Bit Score: 181.85  E-value: 1.44e-48
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936    61 RQQWTRQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRL-GRAGTFLGEVYVNGRALR--REQFQDCFSYVLQSDT 137
Cdd:TIGR00956   69 RDTKTFDILKPMDGLIKPGELTVVLGRPGSGCSTLLKTIASNTdGFHIGVEGVITYDGITPEeiKKHYRGDVVYNAETDV 148
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936   138 LLSSLTVRETLHYTALLAIRRGNPGSFQKKVEA------VMAELSLSHVADRLIGNYSLGGISTGERRRVSIAAQLLQDP 211
Cdd:TIGR00956  149 HFPHLTVGETLDFAARCKTPQNRPDGVSREEYAkhiadvYMATYGLSHTRNTKVGNDFVRGVSGGERKRVSIAEASLGGA 228
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936   212 KVMLFDEPTTGLDCMTANQIVVLLVELAR-RNRIVVLTIHQPRSELFQLFDKIAILSFGELIFCGTPAEMLDFFNDCGYP 290
Cdd:TIGR00956  229 KIQCWDNATRGLDSATALEFIRALKTSANiLDTTPLVAIYQCSQDAYELFDKVIVLYEGYQIYFGPADKAKQYFEKMGFK 308
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936   291 CPEHSNPFDFymdLTSVdTQSKEREI--ETSKRV----QMIESAYKKS-------AICHKTLKNIERMKHLKTLPMVPFK 357
Cdd:TIGR00956  309 CPDRQTTADF---LTSL-TSPAERQIkpGYEKKVprtpQEFETYWRNSpeyaqlmKEIDEYLDRCSESDTKEAYRESHVA 384
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936   358 TKD------SPGVFSKLGVLLRRVTRNLVR---NKLAVITRLLQNLIMGLFLLFFVLRVRSNVLKGAIqdRVGLLYQFVG 428
Cdd:TIGR00956  385 KQSkrtrpsSPYTVSFSMQVKYCLARNFLRmkgNPSFTLFMVFGNIIMALILSSVFYNLPKNTSDFYS--RGGALFFAIL 462
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936   429 ATPYTGMLNAVNLFPVlRAVSDQESQDGLYQKWQMMLAYALHVLPFSVVATMIFSSVCYWTLGLHPEVARFGY-----FS 503
Cdd:TIGR00956  463 FNAFSSLLEIASMYEA-RPIVEKHRKYALYHPSADAIASIISEIPFKIIESVVFNIILYFMVNFRRTAGRFFFyllilFI 541

                   ....*...
gi 530367936   504 AALLAPHL 511
Cdd:TIGR00956  542 CTLAMSHL 549
NatA COG4555
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ...
66-282 4.13e-46

ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 443618 [Multi-domain]  Cd Length: 243  Bit Score: 161.95  E-value: 4.13e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  66 RQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLgRAGTflGEVYVNGRALRRE--QFQDCFSYVLQSDTLLSSLT 143
Cdd:COG4555   14 VPALKDVSFTAKDGEITGLLGPNGAGKTTLLRMLAGLL-KPDS--GSILIDGEDVRKEprEARRQIGVLPDERGLYDRLT 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 144 VRETLHYTALLairRGNPGS-FQKKVEAVMAELSLSHVADRLIGNYSlggisTGERRRVSIAAQLLQDPKVMLFDEPTTG 222
Cdd:COG4555   91 VRENIRYFAEL---YGLFDEeLKKRIEELIELLGLEEFLDRRVGELS-----TGMKKKVALARALVHDPKVLLLDEPTNG 162
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 223 LDCMTANQIVVLLVELARRNRIVVLTIHQPrSELFQLFDKIAILSFGELIFCGTPAEMLD 282
Cdd:COG4555  163 LDVMARRLLREILRALKKEGKTVLFSSHIM-QEVEALCDRVVILHKGKVVAQGSLDELRE 221
3a01205 TIGR00956
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
65-549 7.92e-45

Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273362 [Multi-domain]  Cd Length: 1394  Bit Score: 170.67  E-value: 7.92e-45
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936    65 TRQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGTFLGEVYVNGRAlRREQFQDCFSYVLQSDTLLSSLTV 144
Cdd:TIGR00956  775 KRVILNNVDGWVKPGTLTALMGASGAGKTTLLNVLAERVTTGVITGGDRLVNGRP-LDSSFQRSIGYVQQQDLHLPTSTV 853
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936   145 RETLHYTALLaiRRGNPGSFQKK---VEAVMAELSLSHVADRLIGnYSLGGISTGERRRVSIAAQLLQDPKVMLF-DEPT 220
Cdd:TIGR00956  854 RESLRFSAYL--RQPKSVSKSEKmeyVEEVIKLLEMESYADAVVG-VPGEGLNVEQRKRLTIGVELVAKPKLLLFlDEPT 930
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936   221 TGLDCMTANQIVVLLVELARRNRIVVLTIHQPRSELFQLFDKIAILS-------FGEL-IFCGTpaeMLDFFNDCGYP-C 291
Cdd:TIGR00956  931 SGLDSQTAWSICKLMRKLADHGQAILCTIHQPSAILFEEFDRLLLLQkggqtvyFGDLgENSHT---IINYFEKHGAPkC 1007
                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936   292 PEHSNPFDFYMDLTSVDTqskereieTSKRVQMIESAYKKSAICHKTLKNIERM-KHLKTLPMVPFKTKDSPGVFSKLGV 370
Cdd:TIGR00956 1008 PEDANPAEWMLEVIGAAP--------GAHANQDYHEVWRNSSEYQAVKNELDRLeAELSKAEDDNDPDALSKYAASLWYQ 1079
                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936   371 LLRRVTRNLV---RNKLAVITRLLQNLIMGLFLLFFVLRVRSNvLKGaIQDRVGLLYQFVgaTPYTGMLNA-VNLFPVLR 446
Cdd:TIGR00956 1080 FKLVLWRTFQqywRTPDYLYSKFFLTIFAALFIGFTFFKVGTS-LQG-LQNQMFAVFMAT--VLFNPLIQQyLPPFVAQR 1155
                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936   447 AVSD-QESQDGLYQKWQMMLAYALHVLPFSVVATMIFSSVCYWTLGLHPEVA-------RFGYFSAALLAPHLIgeFLTL 518
Cdd:TIGR00956 1156 DLYEvRERPSRTFSWLAFIAAQITVEIPYNLVAGTIFFFIWYYPVGFYWNASktgqvheRGVLFWLLSTMFFLY--FSTL 1233
                          490       500       510
                   ....*....|....*....|....*....|..
gi 530367936   519 VLLGIVQNPNIVN-SVVALLSIAGVLVGSGFL 549
Cdd:TIGR00956 1234 GQMVISFNPNADNaAVLASLLFTMCLSFCGVL 1265
ABCG_PDR_domain2 cd03232
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ...
65-275 6.60e-42

Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213199 [Multi-domain]  Cd Length: 192  Bit Score: 148.93  E-value: 6.60e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  65 TRQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRlGRAGTFLGEVYVNGRALrREQFQDCFSYVLQSDTLLSSLTV 144
Cdd:cd03232   19 KRQLLNNISGYVKPGTLTALMGESGAGKTTLLDVLAGR-KTAGVITGEILINGRPL-DKNFQRSTGYVEQQDVHSPNLTV 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 145 RETLHYTALLAirrgnpgsfqkkveavmaelslshvadrlignyslgGISTGERRRVSIAAQLLQDPKVMLFDEPTTGLD 224
Cdd:cd03232   97 REALRFSALLR------------------------------------GLSVEQRKRLTIGVELAAKPSILFLDEPTSGLD 140
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 530367936 225 CMTANQIVVLLVELARRNRIVVLTIHQPRSELFQLFDKIAIL-SFGELIFCG 275
Cdd:cd03232  141 SQAAYNIVRFLKKLADSGQAILCTIHQPSASIFEKFDRLLLLkRGGKTVYFG 192
FepC COG1120
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ...
66-282 2.07e-41

ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];


Pssm-ID: 440737 [Multi-domain]  Cd Length: 254  Bit Score: 149.81  E-value: 2.07e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  66 RQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGtflGEVYVNGR---ALRREQFQDCFSYVLQSDTLLSSL 142
Cdd:COG1120   14 RPVLDDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSS---GEVLLDGRdlaSLSRRELARRIAYVPQEPPAPFGL 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 143 TVRETLhytaLLAiRRGNPGSFQK-------KVEAVMAELSLSHVADRLIGNyslggISTGERRRVSIAAQLLQDPKVML 215
Cdd:COG1120   91 TVRELV----ALG-RYPHLGLFGRpsaedreAVEEALERTGLEHLADRPVDE-----LSGGERQRVLIARALAQEPPLLL 160
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 530367936 216 FDEPTTGLDcmTANQIVVL--LVELAR-RNRIVVLTIHQPrsEL-FQLFDKIAILSFGELIFCGTPAEMLD 282
Cdd:COG1120  161 LDEPTSHLD--LAHQLEVLelLRRLAReRGRTVVMVLHDL--NLaARYADRLVLLKDGRIVAQGPPEEVLT 227
ABC_subfamily_A cd03263
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ...
65-279 6.80e-41

ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.


Pssm-ID: 213230 [Multi-domain]  Cd Length: 220  Bit Score: 147.27  E-value: 6.80e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  65 TRQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLgRAGTflGEVYVNGRALR--REQFQDCFSYVLQSDTLLSSL 142
Cdd:cd03263   14 TKPAVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGEL-RPTS--GTAYINGYSIRtdRKAARQSLGYCPQFDALFDEL 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 143 TVRETLHYTALLairRGNPGSFQKK-VEAVMAELSLSHVADRLIGNYSlggisTGERRRVSIAAQLLQDPKVMLFDEPTT 221
Cdd:cd03263   91 TVREHLRFYARL---KGLPKSEIKEeVELLLRVLGLTDKANKRARTLS-----GGMKRKLSLAIALIGGPSVLLLDEPTS 162
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 530367936 222 GLDCMTANQIVVLLVELaRRNRIVVLTIHQPRsELFQLFDKIAILSFGELIFCGTPAE 279
Cdd:cd03263  163 GLDPASRRAIWDLILEV-RKGRSIILTTHSMD-EAEALCDRIAIMSDGKLRCIGSPQE 218
PLN03140 PLN03140
ABC transporter G family member; Provisional
68-499 5.60e-40

ABC transporter G family member; Provisional


Pssm-ID: 215599 [Multi-domain]  Cd Length: 1470  Bit Score: 156.16  E-value: 5.60e-40
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936   68 ILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGTFLGEVYVNGRALRREQFQDCFSYVLQSDTLLSSLTVRET 147
Cdd:PLN03140  180 ILKDASGIIKPSRMTLLLGPPSSGKTTLLLALAGKLDPSLKVSGEITYNGYRLNEFVPRKTSAYISQNDVHVGVMTVKET 259
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  148 LHYTAL-------------LAIRRGNPGSF-QKKVEAVMAELSLSHVADRLIGNYSLG------------------GIST 195
Cdd:PLN03140  260 LDFSARcqgvgtrydllseLARREKDAGIFpEAEVDLFMKATAMEGVKSSLITDYTLKilgldickdtivgdemirGISG 339
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  196 GERRRVSIAAQLLQDPKVMLFDEPTTGLDCMTANQIVVLLVELARRNRIVVL-TIHQPRSELFQLFDKIAILSFGELIFC 274
Cdd:PLN03140  340 GQKKRVTTGEMIVGPTKTLFMDEISTGLDSSTTYQIVKCLQQIVHLTEATVLmSLLQPAPETFDLFDDIILLSEGQIVYQ 419
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  275 GTPAEMLDFFNDCGYPCPEHSNPFDFYMDLTS--------VDTQSKEREIETSKRVQMIESAYKKSaichktlknieRMK 346
Cdd:PLN03140  420 GPRDHILEFFESCGFKCPERKGTADFLQEVTSkkdqeqywADRNKPYRYISVSEFAERFKSFHVGM-----------QLE 488
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  347 HLKTLPMVPFKTKDSPGVFSKLGVLLRRVTRN--------LVRNKLAVITRLLQNLIMGLFLLFFVLRVR---SNVLKGA 415
Cdd:PLN03140  489 NELSVPFDKSQSHKAALVFSKYSVPKMELLKAcwdkewllMKRNAFVYVFKTVQIIIVAAIASTVFLRTEmhtRNEEDGA 568
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  416 IqdrvgllyqFVGATPYTGMLNAVNLFPVLRAVSDQ-----ESQDGLYQ-KWQMMLAYALHVLPFSVVATMIFSSVCYWT 489
Cdd:PLN03140  569 L---------YIGALLFSMIINMFNGFAELALMIQRlpvfyKQRDLLFHpPWTFTLPTFLLGIPISIIESVVWVVITYYS 639
                         490
                  ....*....|
gi 530367936  490 LGLHPEVARF 499
Cdd:PLN03140  640 IGFAPEASRF 649
MlaF COG1127
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ...
66-282 1.26e-38

ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440744 [Multi-domain]  Cd Length: 241  Bit Score: 141.66  E-value: 1.26e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  66 RQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGtflGEVYVNG-----------RALRREqfqdcFSYVLQ 134
Cdd:COG1127   18 RVVLDGVSLDVPRGEILAIIGGSGSGKSVLLKLIIGLLRPDS---GEILVDGqditglsekelYELRRR-----IGMLFQ 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 135 SDTLLSSLTVRETLHYtALLAIRRGNPGSFQKKVEAVMAELSLSHVADRLIGNyslggISTGERRRVSIAAQLLQDPKVM 214
Cdd:COG1127   90 GGALFDSLTVFENVAF-PLREHTDLSEAEIRELVLEKLELVGLPGAADKMPSE-----LSGGMRKRVALARALALDPEIL 163
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 530367936 215 LFDEPTTGLDCMTANQIVVLLVELARRNRIVVLTI-HQpRSELFQLFDKIAILSFGELIFCGTPAEMLD 282
Cdd:COG1127  164 LYDEPTAGLDPITSAVIDELIRELRDELGLTSVVVtHD-LDSAFAIADRVAVLADGKIIAEGTPEELLA 231
ABC_Org_Solvent_Resistant cd03261
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ...
65-282 1.59e-37

ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213228 [Multi-domain]  Cd Length: 235  Bit Score: 138.40  E-value: 1.59e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  65 TRQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGtflGEVYVNGR---ALRREQFQDC---FSYVLQSDTL 138
Cdd:cd03261   12 GRTVLKGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRPDS---GEVLIDGEdisGLSEAELYRLrrrMGMLFQSGAL 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 139 LSSLTVRETLHYtALLAIRRGNPGSFQKKVEAVMAELSLSHVADRLIGNyslggISTGERRRVSIAAQLLQDPKVMLFDE 218
Cdd:cd03261   89 FDSLTVFENVAF-PLREHTRLSEEEIREIVLEKLEAVGLRGAEDLYPAE-----LSGGMKKRVALARALALDPELLLYDE 162
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 530367936 219 PTTGLDCMTANQIVVLLVELARRNRIVVLTIHQPRSELFQLFDKIAILSFGELIFCGTPAEMLD 282
Cdd:cd03261  163 PTAGLDPIASGVIDDLIRSLKKELGLTSIMVTHDLDTAFAIADRIAVLYDGKIVAEGTPEELRA 226
EcfA2 COG1122
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ...
66-281 1.53e-35

Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];


Pssm-ID: 440739 [Multi-domain]  Cd Length: 230  Bit Score: 132.84  E-value: 1.53e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  66 RQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGrLGRAGTflGEVYVNGRALRREQFQDCFS---YVLQ-SDTLLSS 141
Cdd:COG1122   14 TPALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNG-LLKPTS--GEVLVDGKDITKKNLRELRRkvgLVFQnPDDQLFA 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 142 LTVRETLHYtALLaiRRGNPGSF-QKKVEAVMAELSLSHVADRLIgnYSLggiSTGERRRVSIAAQLLQDPKVMLFDEPT 220
Cdd:COG1122   91 PTVEEDVAF-GPE--NLGLPREEiRERVEEALELVGLEHLADRPP--HEL---SGGQKQRVAIAGVLAMEPEVLVLDEPT 162
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 530367936 221 TGLDCMTANQIVVLLVELARRNRIVVLTIHQPRsELFQLFDKIAILSFGELIFCGTPAEML 281
Cdd:COG1122  163 AGLDPRGRRELLELLKRLNKEGKTVIIVTHDLD-LVAELADRVIVLDDGRIVADGTPREVF 222
CcmA COG4133
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ...
66-252 4.09e-35

ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443308 [Multi-domain]  Cd Length: 206  Bit Score: 131.06  E-value: 4.09e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  66 RQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGtflGEVYVNGRALR--REQFQDCFSYVLQSDTLLSSLT 143
Cdd:COG4133   15 RLLFSGLSFTLAAGEALALTGPNGSGKTTLLRILAGLLPPSA---GEVLWNGEPIRdaREDYRRRLAYLGHADGLKPELT 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 144 VRETLHYTALLAIRRGNPGSfqkkVEAVMAELSLSHVADRLIGNYslggiSTGERRRVSIAAQLLQDPKVMLFDEPTTGL 223
Cdd:COG4133   92 VRENLRFWAALYGLRADREA----IDEALEAVGLAGLADLPVRQL-----SAGQKRRVALARLLLSPAPLWLLDEPFTAL 162
                        170       180
                 ....*....|....*....|....*....
gi 530367936 224 DCMTANQIVVLLVELARRNRIVVLTIHQP 252
Cdd:COG4133  163 DAAGVALLAELIAAHLARGGAVLLTTHQP 191
ABC_cobalt_CbiO_domain1 cd03225
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ...
56-270 4.50e-35

First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213192 [Multi-domain]  Cd Length: 211  Bit Score: 131.05  E-value: 4.50e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  56 DITSCRQQWTRQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGtflGEVYVNGRALRREQFQDCF---SYV 132
Cdd:cd03225    4 NLSFSYPDGARPALDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGPTS---GEVLVDGKDLTKLSLKELRrkvGLV 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 133 LQ-SDTLLSSLTVRETLhytALLAIRRGNPGS-FQKKVEAVMAELSLSHVADRLIgnYSLGGistGERRRVSIAAQLLQD 210
Cdd:cd03225   81 FQnPDDQFFGPTVEEEV---AFGLENLGLPEEeIEERVEEALELVGLEGLRDRSP--FTLSG---GQKQRVAIAGVLAMD 152
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 211 PKVMLFDEPTTGLDCMTANQIVVLLVELARRNRIVVLTIHQPrSELFQLFDKIAILSFGE 270
Cdd:cd03225  153 PDILLLDEPTAGLDPAGRRELLELLKKLKAEGKTIIIVTHDL-DLLLELADRVIVLEDGK 211
ZnuC COG1121
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ...
66-282 3.27e-34

ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440738 [Multi-domain]  Cd Length: 245  Bit Score: 129.82  E-value: 3.27e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  66 RQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGtflGEVYVNGRALRREQFQdcFSYVLQSDTLLSS--LT 143
Cdd:COG1121   19 RPVLEDVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLPPTS---GTVRLFGKPPRRARRR--IGYVPQRAEVDWDfpIT 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 144 VRETL---HYTALLAIRRGNPGSFQkKVEAVMAELSLSHVADRLIGnySLGGistGERRRVSIAAQLLQDPKVMLFDEPT 220
Cdd:COG1121   94 VRDVVlmgRYGRRGLFRRPSRADRE-AVDEALERVGLEDLADRPIG--ELSG---GQQQRVLLARALAQDPDLLLLDEPF 167
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 530367936 221 TGLDCMTANQIVVLLVELARRNRIVVLTIHQPrSELFQLFDKIAILSfGELIFCGTPAEMLD 282
Cdd:COG1121  168 AGVDAATEEALYELLRELRREGKTILVVTHDL-GAVREYFDRVLLLN-RGLVAHGPPEEVLT 227
ABC_DR_subfamily_A cd03230
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ...
65-271 5.13e-34

ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213197 [Multi-domain]  Cd Length: 173  Bit Score: 126.74  E-value: 5.13e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  65 TRQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLgRAGTflGEVYVNGRALRRE--QFQDCFSYVLQSDTLLSSL 142
Cdd:cd03230   12 KKTALDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLL-KPDS--GEIKVLGKDIKKEpeEVKRRIGYLPEEPSLYENL 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 143 TVRETLHYtallairrgnpgsfqkkveavmaelslshvadrlignyslggiSTGERRRVSIAAQLLQDPKVMLFDEPTTG 222
Cdd:cd03230   89 TVRENLKL-------------------------------------------SGGMKQRLALAQALLHDPELLILDEPTSG 125
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 530367936 223 LDCMTANQIVVLLVELARRNRIVVLTIHQPrSELFQLFDKIAILSFGEL 271
Cdd:cd03230  126 LDPESRREFWELLRELKKEGKTILLSSHIL-EEAERLCDRVAILNNGRI 173
PLN03140 PLN03140
ABC transporter G family member; Provisional
67-502 4.22e-33

ABC transporter G family member; Provisional


Pssm-ID: 215599 [Multi-domain]  Cd Length: 1470  Bit Score: 135.36  E-value: 4.22e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936   67 QILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRlgRAGTFL-GEVYVNGRALRREQFQDCFSYVLQSDTLLSSLTVR 145
Cdd:PLN03140  894 QLLREVTGAFRPGVLTALMGVSGAGKTTLMDVLAGR--KTGGYIeGDIRISGFPKKQETFARISGYCEQNDIHSPQVTVR 971
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  146 ETLHYTALLaiRRGNPGSFQKK---VEAVMAELSLSHVADRLIGNYSLGGISTGERRRVSIAAQLLQDPKVMLFDEPTTG 222
Cdd:PLN03140  972 ESLIYSAFL--RLPKEVSKEEKmmfVDEVMELVELDNLKDAIVGLPGVTGLSTEQRKRLTIAVELVANPSIIFMDEPTSG 1049
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  223 LDCMTAnQIVVLLVelarRN-----RIVVLTIHQPRSELFQLFDKIAILSF-GELIFCGT----PAEMLDFFNDC-GYP- 290
Cdd:PLN03140 1050 LDARAA-AIVMRTV----RNtvdtgRTVVCTIHQPSIDIFEAFDELLLMKRgGQVIYSGPlgrnSHKIIEYFEAIpGVPk 1124
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  291 CPEHSNPFDFYMDLTSVDTQSKeREIETSKRvqmiesaYKKSAICHktlKNIERMKHLKTLPM----VPFKTKDSPGVFS 366
Cdd:PLN03140 1125 IKEKYNPATWMLEVSSLAAEVK-LGIDFAEH-------YKSSSLYQ---RNKALVKELSTPPPgasdLYFATQYSQSTWG 1193
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  367 KLGVLL--------RRVTRNLVRNKLAVITRLlqnLIMGLFLLFFVLRVRSNVLKGAIqdrvGLLYqfvGATPYTGMLNA 438
Cdd:PLN03140 1194 QFKSCLwkqwwtywRSPDYNLVRFFFTLAAAL---MVGTIFWKVGTKRSNANDLTMVI----GAMY---AAVLFVGINNC 1263
                         410       420       430       440       450       460
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 530367936  439 VNLFPVL---RAVSDQESQDGLYQKWQMMLAYALHVLPFSVVATMIFSSVCYWTLGLHPEVARFGYF 502
Cdd:PLN03140 1264 STVQPMVaveRTVFYRERAAGMYSALPYAIAQVVCEIPYVLIQTTYYTLIVYAMVAFEWTAAKFFWF 1330
ABC_Iron-Siderophores_B12_Hemin cd03214
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ...
66-275 1.18e-32

ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.


Pssm-ID: 213181 [Multi-domain]  Cd Length: 180  Bit Score: 123.31  E-value: 1.18e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  66 RQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGtflGEVYVNGRALR---REQFQDCFSYVLQsdtllssl 142
Cdd:cd03214   12 RTVLDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSS---GEILLDGKDLAslsPKELARKIAYVPQ-------- 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 143 tvretlhytallairrgnpgsfqkkveaVMAELSLSHVADRLIGNyslggISTGERRRVSIAAQLLQDPKVMLFDEPTTG 222
Cdd:cd03214   81 ----------------------------ALELLGLAHLADRPFNE-----LSGGERQRVLLARALAQEPPILLLDEPTSH 127
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 530367936 223 LDcmTANQIVVL--LVELAR-RNRIVVLTIHQPrsEL-FQLFDKIAILSFGELIFCG 275
Cdd:cd03214  128 LD--IAHQIELLelLRRLAReRGKTVVMVLHDL--NLaARYADRVILLKDGRIVAQG 180
ABCG_PDR_domain1 cd03233
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ...
53-275 3.22e-32

First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213200 [Multi-domain]  Cd Length: 202  Bit Score: 122.76  E-value: 3.22e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  53 PWWDITSCRQQ--WTRQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGTFLGEVYVNGRALR--REQFQDC 128
Cdd:cd03233    5 SWRNISFTTGKgrSKIPILKDFSGVVKPGEMVLVLGRPGSGCSTLLKALANRTEGNVSVEGDIHYNGIPYKefAEKYPGE 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 129 FSYVLQSDTLLSSLTVRETLHYTAllairrgnpgsfqkkveavmaelslshvadRLIGNYSLGGISTGERRRVSIAAQLL 208
Cdd:cd03233   85 IIYVSEEDVHFPTLTVRETLDFAL------------------------------RCKGNEFVRGISGGERKRVSIAEALV 134
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 530367936 209 QDPKVMLFDEPTTGLDCMTANQIVVLLVELARRNRIVVL-TIHQPRSELFQLFDKIAILSFGELIFCG 275
Cdd:cd03233  135 SRASVLCWDNSTRGLDSSTALEILKCIRTMADVLKTTTFvSLYQASDEIYDLFDKVLVLYEGRQIYYG 202
ABC_Carb_Solutes_like cd03259
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ...
67-275 3.83e-32

ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213226 [Multi-domain]  Cd Length: 213  Bit Score: 123.01  E-value: 3.83e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  67 QILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGrLGRAGTflGEVYVNGRAL------RREqfqdcFSYVLQSDTLLS 140
Cdd:cd03259   14 RALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAG-LERPDS--GEILIDGRDVtgvppeRRN-----IGMVFQDYALFP 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 141 SLTVRETLHYTalLAIRRGNPGSFQKKVEAVMAELSLSHVADRLIgnyslGGISTGERRRVSIAAQLLQDPKVMLFDEPT 220
Cdd:cd03259   86 HLTVAENIAFG--LKLRGVPKAEIRARVRELLELVGLEGLLNRYP-----HELSGGQQQRVALARALAREPSLLLLDEPL 158
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 530367936 221 TGLDCMTANQIVVLLVELARRNRI-VVLTIHQPrSELFQLFDKIAILSFGELIFCG 275
Cdd:cd03259  159 SALDAKLREELREELKELQRELGItTIYVTHDQ-EEALALADRIAVMNEGRIVQVG 213
ABC_tran pfam00005
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ...
69-221 4.19e-32

ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.


Pssm-ID: 394964 [Multi-domain]  Cd Length: 150  Bit Score: 120.83  E-value: 4.19e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936   69 LKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGtflGEVYVNGRALR---REQFQDCFSYVLQSDTLLSSLTVR 145
Cdd:pfam00005   1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTE---GTILLDGQDLTddeRKSLRKEIGYVFQDPQLFPRLTVR 77
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 530367936  146 ETLHYTALLAIRRGNPgsFQKKVEAVMAELSLSHVADRLIGNYSlGGISTGERRRVSIAAQLLQDPKVMLFDEPTT 221
Cdd:pfam00005  78 ENLRLGLLLKGLSKRE--KDARAEEALEKLGLGDLADRPVGERP-GTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150
GsiA COG1123
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...
65-282 5.04e-32

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440740 [Multi-domain]  Cd Length: 514  Bit Score: 129.64  E-value: 5.04e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  65 TRQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGTFLGEVYVNGRALRREQFQDC---FSYVLQS-DTLLS 140
Cdd:COG1123   18 DVPAVDGVSLTIAPGETVALVGESGSGKSTLALALMGLLPHGGRISGEVLLDGRDLLELSEALRgrrIGMVFQDpMTQLN 97
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 141 SLTVRETLHYTalLAIRRGNPGSFQKKVEAVMAELSLSHVADRLIGNyslggISTGERRRVSIAAQLLQDPKVMLFDEPT 220
Cdd:COG1123   98 PVTVGDQIAEA--LENLGLSRAEARARVLELLEAVGLERRLDRYPHQ-----LSGGQRQRVAIAMALALDPDLLIADEPT 170
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 530367936 221 TGLDCMTANQIVVLLVELARRNRIVVLTIHQPRSELFQLFDKIAILSFGELIFCGTPAEMLD 282
Cdd:COG1123  171 TALDVTTQAEILDLLRELQRERGTTVLLITHDLGVVAEIADRVVVMDDGRIVEDGPPEEILA 232
ABC_MJ0796_LolCDE_FtsE cd03255
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ...
65-271 5.50e-32

ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.


Pssm-ID: 213222 [Multi-domain]  Cd Length: 218  Bit Score: 122.60  E-value: 5.50e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  65 TRQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGrLGRAGTflGEVYVNGR-----------ALRREQfqdcFSYVL 133
Cdd:cd03255   16 KVQALKGVSLSIEKGEFVAIVGPSGSGKSTLLNILGG-LDRPTS--GEVRVDGTdisklsekelaAFRRRH----IGFVF 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 134 QSDTLLSSLTVRETLhytALLAIRRGNPGSFQK-KVEAVMAELSLSHVADRLIGNyslggISTGERRRVSIAAQLLQDPK 212
Cdd:cd03255   89 QSFNLLPDLTALENV---ELPLLLAGVPKKERReRAEELLERVGLGDRLNHYPSE-----LSGGQQQRVAIARALANDPK 160
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 213 VMLFDEPTTGLDCMTANQIVVLLVELAR-RNRIVVLTIHQPrsELFQLFDKIAILSFGEL 271
Cdd:cd03255  161 IILADEPTGNLDSETGKEVMELLRELNKeAGTTIVVVTHDP--ELAEYADRIIELRDGKI 218
ABC_Metallic_Cations cd03235
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ...
66-275 6.30e-32

ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.


Pssm-ID: 213202 [Multi-domain]  Cd Length: 213  Bit Score: 122.26  E-value: 6.30e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  66 RQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGtflGEVYVNGRALRREQFQdcFSYVLQSDTLLSS--LT 143
Cdd:cd03235   12 HPVLEDVSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLKPTS---GSIRVFGKPLEKERKR--IGYVPQRRSIDRDfpIS 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 144 VRETLhytaLLAiRRGNPGSFQ-------KKVEAVMAELSLSHVADRLIGNyslggISTGERRRVSIAAQLLQDPKVMLF 216
Cdd:cd03235   87 VRDVV----LMG-LYGHKGLFRrlskadkAKVDEALERVGLSELADRQIGE-----LSGGQQQRVLLARALVQDPDLLLL 156
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 530367936 217 DEPTTGLDCMTANQIVVLLVELARRNRIVVLTIHQPrSELFQLFDKIAILSfGELIFCG 275
Cdd:cd03235  157 DEPFAGVDPKTQEDIYELLRELRREGMTILVVTHDL-GLVLEYFDRVLLLN-RTVVASG 213
ABC_Mj1267_LivG_branched cd03219
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ...
69-279 4.10e-31

ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).


Pssm-ID: 213186 [Multi-domain]  Cd Length: 236  Bit Score: 121.00  E-value: 4.10e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  69 LKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLgRAGTflGEVYVNGRALRREQ------------FQdcfsyVLQsd 136
Cdd:cd03219   16 LDDVSFSVRPGEIHGLIGPNGAGKTTLFNLISGFL-RPTS--GSVLFDGEDITGLPpheiarlgigrtFQ-----IPR-- 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 137 tLLSSLTVRETL--------HYTALLAIRRGNPGSFQKKVEAVMAELSLSHVADRLIGNyslggISTGERRRVSIAAQLL 208
Cdd:cd03219   86 -LFPELTVLENVmvaaqartGSGLLLARARREEREARERAEELLERVGLADLADRPAGE-----LSYGQQRRLEIARALA 159
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 530367936 209 QDPKVMLFDEPTTGLDCMTANQIVVLLVELARRNRIVVLTIHQPRSeLFQLFDKIAILSFGELIFCGTPAE 279
Cdd:cd03219  160 TDPKLLLLDEPAAGLNPEETEELAELIRELRERGITVLLVEHDMDV-VMSLADRVTVLDQGRVIAEGTPDE 229
LolD COG1136
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
65-272 5.64e-31

ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440751 [Multi-domain]  Cd Length: 227  Bit Score: 120.15  E-value: 5.64e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  65 TRQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGrLGRAGTflGEVYVNGR-----------ALRREQfqdcFSYVL 133
Cdd:COG1136   20 EVTALRGVSLSIEAGEFVAIVGPSGSGKSTLLNILGG-LDRPTS--GEVLIDGQdisslserelaRLRRRH----IGFVF 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 134 QSDTLLSSLTVRETLhytAL-LAIRRGNPGSFQKKVEAVMAELSLSHVADRLIGNyslggISTGERRRVSIAAQLLQDPK 212
Cdd:COG1136   93 QFFNLLPELTALENV---ALpLLLAGVSRKERRERARELLERVGLGDRLDHRPSQ-----LSGGQQQRVAIARALVNRPK 164
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 530367936 213 VMLFDEPTTGLDCMTANQIVVLLVELARR-NRIVVLTIHQPRseLFQLFDKIAILSFGELI 272
Cdd:COG1136  165 LILADEPTGNLDSKTGEEVLELLRELNRElGTTIVMVTHDPE--LAARADRVIRLRDGRIV 223
ABC_YhbG cd03218
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ...
65-281 5.66e-31

ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.


Pssm-ID: 213185 [Multi-domain]  Cd Length: 232  Bit Score: 120.34  E-value: 5.66e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  65 TRQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGrLGRAGTflGEVYVNGRALRR----EQFQDCFSYVLQSDTLLS 140
Cdd:cd03218   12 KRKVVNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVG-LVKPDS--GKILLDGQDITKlpmhKRARLGIGYLPQEASIFR 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 141 SLTVRETLhyTALLAIRRGNPGSFQKKVEAVMAELSLSHVADRLigNYSLGGistGERRRVSIAAQLLQDPKVMLFDEPT 220
Cdd:cd03218   89 KLTVEENI--LAVLEIRGLSKKEREEKLEELLEEFHITHLRKSK--ASSLSG---GERRRVEIARALATNPKFLLLDEPF 161
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 530367936 221 TGLDCMTANQIVVLLVELARRNRIVVLTIHQPRsELFQLFDKIAILSFGELIFCGTPAEML 281
Cdd:cd03218  162 AGVDPIAVQDIQKIIKILKDRGIGVLITDHNVR-ETLSITDRAYIIYEGKVLAEGTPEEIA 221
ABC_ATPase cd00267
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ...
65-270 3.34e-30

ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213179 [Multi-domain]  Cd Length: 157  Bit Score: 115.80  E-value: 3.34e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  65 TRQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGtflGEVYVNGRALRR---EQFQDCFSYVLQsdtllss 141
Cdd:cd00267   11 GRTALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTS---GEILIDGKDIAKlplEELRRRIGYVPQ------- 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 142 ltvretlhytallairrgnpgsfqkkveavmaelslshvadrlignyslggISTGERRRVSIAAQLLQDPKVMLFDEPTT 221
Cdd:cd00267   81 ---------------------------------------------------LSGGQRQRVALARALLLNPDLLLLDEPTS 109
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 530367936 222 GLDCMTANQIVVLLVELARRNRIVVLTIHQPrSELFQLFDKIAILSFGE 270
Cdd:cd00267  110 GLDPASRERLLELLRELAEEGRTVIIVTHDP-ELAELAADRVIVLKDGK 157
ABC_DrrA cd03265
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ...
69-280 3.56e-30

Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213232 [Multi-domain]  Cd Length: 220  Bit Score: 117.86  E-value: 3.56e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  69 LKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGtflGEVYVNGRALRRE--QFQDCFSYVLQSDTLLSSLTVRE 146
Cdd:cd03265   16 VRGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPTS---GRATVAGHDVVREprEVRRRIGIVFQDLSVDDELTGWE 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 147 TLHYTALLAirrGNPGS-FQKKVEAVMAELSLSHVADRLIGNYSlggisTGERRRVSIAAQLLQDPKVMLFDEPTTGLDC 225
Cdd:cd03265   93 NLYIHARLY---GVPGAeRRERIDELLDFVGLLEAADRLVKTYS-----GGMRRRLEIARSLVHRPEVLFLDEPTIGLDP 164
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 530367936 226 MTANQIVVLLVELARRNRIVVLTIHQPRSELFQLFDKIAILSFGELIFCGTPAEM 280
Cdd:cd03265  165 QTRAHVWEYIEKLKEEFGMTILLTTHYMEEAEQLCDRVAIIDHGRIIAEGTPEEL 219
ABC_NrtD_SsuB_transporters cd03293
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ...
65-267 6.19e-30

ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213260 [Multi-domain]  Cd Length: 220  Bit Score: 117.19  E-value: 6.19e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  65 TRQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGrLGRAGTflGEVYVNGRALRREQFQdcFSYVLQSDTLLSSLTV 144
Cdd:cd03293   16 AVTALEDISLSVEEGEFVALVGPSGCGKSTLLRIIAG-LERPTS--GEVLVDGEPVTGPGPD--RGYVFQQDALLPWLTV 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 145 RETlhyTAL-LAIRRGNPGSFQKKVEAVMAELSLSHVADRLIGNyslggISTGERRRVSIAAQLLQDPKVMLFDEPTTGL 223
Cdd:cd03293   91 LDN---VALgLELQGVPKAEARERAEELLELVGLSGFENAYPHQ-----LSGGMRQRVALARALAVDPDVLLLDEPFSAL 162
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 530367936 224 DCMTANQIVVLLVELARRNRIVVLTIHQPRSELFQLFDKIAILS 267
Cdd:cd03293  163 DALTREQLQEELLDIWRETGKTVLLVTHDIDEAVFLADRVVVLS 206
ABC_drug_resistance_like cd03264
ABC-type multidrug transport system, ATPase component; The biological function of this family ...
66-275 5.62e-29

ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213231 [Multi-domain]  Cd Length: 211  Bit Score: 114.21  E-value: 5.62e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  66 RQILKDVSLYVESGqIMCILGSSGSGKTTLLDAMSGRL-GRAGTflgeVYVNGRALR--REQFQDCFSYVLQSDTLLSSL 142
Cdd:cd03264   13 KRALDGVSLTLGPG-MYGLLGPNGAGKTTLMRILATLTpPSSGT----IRIDGQDVLkqPQKLRRRIGYLPQEFGVYPNF 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 143 TVRETLHYTALLaiRRGNPGSFQKKVEAVMAELSLSHVADRLIGNYSlGGIstgeRRRVSIAAQLLQDPKVMLFDEPTTG 222
Cdd:cd03264   88 TVREFLDYIAWL--KGIPSKEVKARVDEVLELVNLGDRAKKKIGSLS-GGM----RRRVGIAQALVGDPSILIVDEPTAG 160
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 530367936 223 LDcmTANQIVV--LLVELArRNRIVVLTIHQpRSELFQLFDKIAILSFGELIFCG 275
Cdd:cd03264  161 LD--PEERIRFrnLLSELG-EDRIVILSTHI-VEDVESLCNQVAVLNKGKLVFEG 211
ABC_BcrA_bacitracin_resist cd03268
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ...
65-273 5.77e-29

ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.


Pssm-ID: 213235 [Multi-domain]  Cd Length: 208  Bit Score: 113.85  E-value: 5.77e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  65 TRQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGrLGRAGTflGEVYVNGralrrEQFQDCFSYVLQSDTLLSS--- 141
Cdd:cd03268   12 KKRVLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILG-LIKPDS--GEITFDG-----KSYQKNIEALRRIGALIEApgf 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 142 ---LTVRETLHYTALLAIRRgnpgsfQKKVEAVMAELSLSHVADRLIGNYSLggistGERRRVSIAAQLLQDPKVMLFDE 218
Cdd:cd03268   84 ypnLTARENLRLLARLLGIR------KKRIDEVLDVVGLKDSAKKKVKGFSL-----GMKQRLGIALALLGNPDLLILDE 152
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 530367936 219 PTTGLDCMTANQIVVLLVELARRNRIVVLTIHQpRSELFQLFDKIAILSFGELIF 273
Cdd:cd03268  153 PTNGLDPDGIKELRELILSLRDQGITVLISSHL-LSEIQKVADRIGIINKGKLIE 206
LptB COG1137
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ...
66-282 8.60e-29

ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440752 [Multi-domain]  Cd Length: 240  Bit Score: 114.36  E-value: 8.60e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  66 RQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGtflGEVYVNGRAL------RREQFQdcFSYVLQSDTLL 139
Cdd:COG1137   16 RTVVKDVSLEVNQGEIVGLLGPNGAGKTTTFYMIVGLVKPDS---GRIFLDGEDIthlpmhKRARLG--IGYLPQEASIF 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 140 SSLTVRETLhyTALLAIRRGNPGSFQKKVEAVMAELSLSHVADRLigNYSLGGistGERRRVSIAAQLLQDPKVMLFDEP 219
Cdd:COG1137   91 RKLTVEDNI--LAVLELRKLSKKEREERLEELLEEFGITHLRKSK--AYSLSG---GERRRVEIARALATNPKFILLDEP 163
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 530367936 220 TTGLDCMTANQIVVLLVELARRNRIVVLTIHQPRsELFQLFDKIAILSFGELIFCGTPAEMLD 282
Cdd:COG1137  164 FAGVDPIAVADIQKIIRHLKERGIGVLITDHNVR-ETLGICDRAYIISEGKVLAEGTPEEILN 225
LPS_export_lptB TIGR04406
LPS export ABC transporter ATP-binding protein; Members of this fmaily are LptB, the ...
66-281 1.36e-28

LPS export ABC transporter ATP-binding protein; Members of this fmaily are LptB, the ATP-binding cassette protein of an ABC transporter involved in lipopolysaccharide export. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]


Pssm-ID: 275199 [Multi-domain]  Cd Length: 239  Bit Score: 113.91  E-value: 1.36e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936   66 RQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGrLGRAGTflGEVYVNGRALRR----EQFQDCFSYVLQSDTLLSS 141
Cdd:TIGR04406  14 RKVVNDVSLSVKSGEIVGLLGPNGAGKTTSFYMIVG-LVRPDA--GKILIDGQDITHlpmhERARLGIGYLPQEASIFRK 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  142 LTVRETLhyTALLAIR-RGNPGSFQKKVEAVMAELSLSHVADRLigNYSLGGistGERRRVSIAAQLLQDPKVMLFDEPT 220
Cdd:TIGR04406  91 LTVEENI--MAVLEIRkDLDRAEREERLEALLEEFQISHLRDNK--AMSLSG---GERRRVEIARALATNPKFILLDEPF 163
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 530367936  221 TGLDCMTANQIVVLLVELARRNRIVVLTIHQPRsELFQLFDKIAILSFGELIFCGTPAEML 281
Cdd:TIGR04406 164 AGVDPIAVGDIKKIIKHLKERGIGVLITDHNVR-ETLDICDRAYIISDGKVLAEGTPAEIV 223
CydC COG4987
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ...
27-281 1.53e-28

ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 444011 [Multi-domain]  Cd Length: 569  Bit Score: 119.87  E-value: 1.53e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  27 GAPATAPEPHSLGILHASYSvshrvrpwWDitscrqQWTRQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGrlgra 106
Cdd:COG4987  323 AEPAPAPGGPSLELEDVSFR--------YP------GAGRPVLDGLSLTLPPGERVAIVGPSGSGKSTLLALLLR----- 383
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 107 gtFL----GEVYVNG---RALRREQFQDCFSYVLQSDTLLSSlTVRETLhytaLLAirrgNPGSFQKKVEAVMAELSLSH 179
Cdd:COG4987  384 --FLdpqsGSITLGGvdlRDLDEDDLRRRIAVVPQRPHLFDT-TLRENL----RLA----RPDATDEELWAALERVGLGD 452
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 180 VADRLIG--NYSLG----GISTGERRRVSIAAQLLQDPKVMLFDEPTTGLDCMTANQIVVLLVELArRNRIVVLTIHQPR 253
Cdd:COG4987  453 WLAALPDglDTWLGeggrRLSGGERRRLALARALLRDAPILLLDEPTEGLDAATEQALLADLLEAL-AGRTVLLITHRLA 531
                        250       260
                 ....*....|....*....|....*...
gi 530367936 254 seLFQLFDKIAILSFGELIFCGTPAEML 281
Cdd:COG4987  532 --GLERMDRILVLEDGRIVEQGTHEELL 557
ABC_NatA_like cd03267
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ...
41-275 8.59e-28

ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.


Pssm-ID: 213234 [Multi-domain]  Cd Length: 236  Bit Score: 111.66  E-value: 8.59e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  41 LHASYSVsHRVRPWWdITSCRQQWTRQ-----ILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGtflGEVYV 115
Cdd:cd03267    6 LSKSYRV-YSKEPGL-IGSLKSLFKRKyreveALKGISFTIEKGEIVGFIGPNGAGKTTTLKILSGLLQPTS---GEVRV 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 116 NGRA--LRREQFQDCFSYVL-QSDTLLSSLTVRETlhYTALLAIRRGNPGSFQKKVEAVMAELSLSHVADRLIGNYSLGg 192
Cdd:cd03267   81 AGLVpwKRRKKFLRRIGVVFgQKTQLWWDLPVIDS--FYLLAAIYDLPPARFKKRLDELSELLDLEELLDTPVRQLSLG- 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 193 istgERRRVSIAAQLLQDPKVMLFDEPTTGLDCMTANQIVVLLVELAR-RNRIVVLTIHQPRsELFQLFDKIAILSFGEL 271
Cdd:cd03267  158 ----QRMRAEIAAALLHEPEILFLDEPTIGLDVVAQENIRNFLKEYNReRGTTVLLTSHYMK-DIEALARRVLVIDKGRL 232

                 ....
gi 530367936 272 IFCG 275
Cdd:cd03267  233 LYDG 236
GsiA COG1123
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ...
65-282 2.06e-27

ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440740 [Multi-domain]  Cd Length: 514  Bit Score: 115.77  E-value: 2.06e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  65 TRQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGtflGEVYVNG-----------RALRRE-Q--FQDCFS 130
Cdd:COG1123  277 GVRAVDDVSLTLRRGETLGLVGESGSGKSTLARLLLGLLRPTS---GSILFDGkdltklsrrslRELRRRvQmvFQDPYS 353
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 131 yvlqsdTLLSSLTVRETLHYtALLAIRRGNPGSFQKKVEAVMAELSLS-HVADRLIgnYSLGGistGERRRVSIAAQLLQ 209
Cdd:COG1123  354 ------SLNPRMTVGDIIAE-PLRLHGLLSRAERRERVAELLERVGLPpDLADRYP--HELSG---GQRQRVAIARALAL 421
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 210 DPKVMLFDEPTTGLDCMTANQIVVLLVELARRNRivvLTIhqprseLF---------QLFDKIAILSFGELIFCGTPAEM 280
Cdd:COG1123  422 EPKLLILDEPTSALDVSVQAQILNLLRDLQRELG---LTY------LFishdlavvrYIADRVAVMYDGRIVEDGPTEEV 492

                 ..
gi 530367936 281 LD 282
Cdd:COG1123  493 FA 494
drrA TIGR01188
daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin ...
69-280 2.49e-27

daunorubicin resistance ABC transporter ATP-binding subunit; This model describes daunorubicin resistance ABC transporter, ATP binding subunit in bacteria and archaea. This model is restricted in its scope to preferentially recognize the ATP binding subunit associated with effux of the drug, daunorubicin. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporter is the obligatory coupling of ATP hydrolysis to substrate translocation. The minimal configuration of bacterial ABC transport system: an ATPase or ATP binding subunit; An integral membrane protein; a hydrophilic polypetpide, which likely functions as substrate binding protein. In eukaryotes proteins of similar function include p-gyco proteins, multidrug resistance protein etc. [Transport and binding proteins, Other]


Pssm-ID: 130256 [Multi-domain]  Cd Length: 302  Bit Score: 112.10  E-value: 2.49e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936   69 LKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRL----GRAGTFLGEVYVNGRALRREqfqdcFSYVLQSDTLLSSLTV 144
Cdd:TIGR01188   9 VDGVNFKVREGEVFGFLGPNGAGKTTTIRMLTTLLrptsGTARVAGYDVVREPRKVRRS-----IGIVPQYASVDEDLTG 83
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  145 RETLHYTALLairRGNPGSF-QKKVEAVMAELSLSHVADRLIGNYSlGGIstgeRRRVSIAAQLLQDPKVMLFDEPTTGL 223
Cdd:TIGR01188  84 RENLEMMGRL---YGLPKDEaEERAEELLELFELGEAADRPVGTYS-GGM----RRRLDIAASLIHQPDVLFLDEPTTGL 155
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 530367936  224 DCMTANQIVVLLVELARRNRIVVLTIHQpRSELFQLFDKIAILSFGELIFCGTPAEM 280
Cdd:TIGR01188 156 DPRTRRAIWDYIRALKEEGVTILLTTHY-MEEADKLCDRIAIIDHGRIIAEGTPEEL 211
FetA COG4619
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];
60-271 4.14e-27

ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 443661 [Multi-domain]  Cd Length: 209  Bit Score: 108.75  E-value: 4.14e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  60 CRQQWTRQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGtflGEVYVNGR--------ALRREqfqdcFSY 131
Cdd:COG4619    7 SFRVGGKPILSPVSLTLEAGECVAITGPSGSGKSTLLRALADLDPPTS---GEIYLDGKplsampppEWRRQ-----VAY 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 132 VLQSDTLLSSlTVRETLHYTALLAIRRGNPgsfqKKVEAVMAELSLSH-VADRLIGNyslggISTGERRRVSIAAQLLQD 210
Cdd:COG4619   79 VPQEPALWGG-TVRDNLPFPFQLRERKFDR----ERALELLERLGLPPdILDKPVER-----LSGGERQRLALIRALLLQ 148
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 530367936 211 PKVMLFDEPTTGLDCMTANQIVVLLVEL-ARRNRIVVLTIHQPRsELFQLFDKIAILSFGEL 271
Cdd:COG4619  149 PDVLLLDEPTSALDPENTRRVEELLREYlAEEGRAVLWVSHDPE-QIERVADRVLTLEAGRL 209
ABC_ModC_like cd03299
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ...
56-281 6.17e-27

ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213266 [Multi-domain]  Cd Length: 235  Bit Score: 108.96  E-value: 6.17e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  56 DITSCRQQWTRQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGtflGEVYVNGRAL------RREqfqdcF 129
Cdd:cd03299    2 KVENLSKDWKEFKLKNVSLEVERGDYFVILGPTGSGKSVLLETIAGFIKPDS---GKILLNGKDItnlppeKRD-----I 73
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 130 SYVLQSDTLLSSLTVRETLHYTalLAIRRGNPGSFQKKVEAVMAELSLSHVADRlignySLGGISTGERRRVSIAAQLLQ 209
Cdd:cd03299   74 SYVPQNYALFPHMTVYKNIAYG--LKKRKVDKKEIERKVLEIAEMLGIDHLLNR-----KPETLSGGEQQRVAIARALVV 146
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 530367936 210 DPKVMLFDEPTTGLDCMTANQIVVLLVELARRNRIVVLTIHQPRSELFQLFDKIAILSFGELIFCGTPAEML 281
Cdd:cd03299  147 NPKILLLDEPFSALDVRTKEKLREELKKIRKEFGVTVLHVTHDFEEAWALADKVAIMLNGKLIQVGKPEEVF 218
ABC_MetN_methionine_transporter cd03258
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ...
69-281 7.88e-27

ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213225 [Multi-domain]  Cd Length: 233  Bit Score: 108.82  E-value: 7.88e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  69 LKDVSLYVESGQIMCILGSSGSGKTTLLDAM-------SGRLGRAGTFLGEVyvNGRALRreQFQDCFSYVLQSDTLLSS 141
Cdd:cd03258   21 LKDVSLSVPKGEIFGIIGRSGAGKSTLIRCInglerptSGSVLVDGTDLTLL--SGKELR--KARRRIGMIFQHFNLLSS 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 142 LTVRETLHYTALLAirrGNPGSFQ-KKVEAVMAELSLSHVADRLIGNyslggISTGERRRVSIAAQLLQDPKVMLFDEPT 220
Cdd:cd03258   97 RTVFENVALPLEIA---GVPKAEIeERVLELLELVGLEDKADAYPAQ-----LSGGQKQRVGIARALANNPKVLLCDEAT 168
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 530367936 221 TGLDCMTANQIVVLLVELARRNRIVVLTI-HQpRSELFQLFDKIAILSFGELIFCGTPAEML 281
Cdd:cd03258  169 SALDPETTQSILALLRDINRELGLTIVLItHE-MEVVKRICDRVAVMEKGEVVEEGTVEEVF 229
TauB COG1116
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ...
65-267 9.23e-27

ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440733 [Multi-domain]  Cd Length: 260  Bit Score: 109.41  E-value: 9.23e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  65 TRQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGrLGRAGTflGEVYVNGRALRREQfQDCfSYVLQSDTLLSSLTV 144
Cdd:COG1116   23 GVTALDDVSLTVAAGEFVALVGPSGCGKSTLLRLIAG-LEKPTS--GEVLVDGKPVTGPG-PDR-GVVFQEPALLPWLTV 97
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 145 RE--TLHytalLAIRRGNPGSFQKKVEAVMAELSLSHVADRLIGNyslggISTGERRRVSIAAQLLQDPKVMLFDEPTTG 222
Cdd:COG1116   98 LDnvALG----LELRGVPKAERRERARELLELVGLAGFEDAYPHQ-----LSGGMRQRVAIARALANDPEVLLMDEPFGA 168
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 530367936 223 LDCMTANQIVVLLVELARRNRIVVLTI-HQPRsELFQLFDKIAILS 267
Cdd:COG1116  169 LDALTRERLQDELLRLWQETGKTVLFVtHDVD-EAVFLADRVVVLS 213
ABC_cobalt_CbiO_domain2 cd03226
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ...
68-250 1.55e-26

Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.


Pssm-ID: 213193 [Multi-domain]  Cd Length: 205  Bit Score: 106.96  E-value: 1.55e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  68 ILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGtflGEVYVNGRALRREQFQDCFSYVLQ-SDTLLSSLTVRE 146
Cdd:cd03226   15 ILDDLSLDLYAGEIIALTGKNGAGKTTLAKILAGLIKESS---GSILLNGKPIKAKERRKSIGYVMQdVDYQLFTDSVRE 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 147 TLHYTAllairrGNPGSFQKKVEAVMAELSLSHVADRLigNYSLGGistGERRRVSIAAQLLQDPKVMLFDEPTTGLDCM 226
Cdd:cd03226   92 ELLLGL------KELDAGNEQAETVLKDLDLYALKERH--PLSLSG---GQKQRLAIAAALLSGKDLLIFDEPTSGLDYK 160
                        170       180
                 ....*....|....*....|....
gi 530367936 227 TANQIVVLLVELARRNRIVVLTIH 250
Cdd:cd03226  161 NMERVGELIRELAAQGKAVIVITH 184
ABC_PhnC_transporter cd03256
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ...
66-279 1.67e-26

ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213223 [Multi-domain]  Cd Length: 241  Bit Score: 108.04  E-value: 1.67e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  66 RQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGtflGEVYVNG-----------RALRREqfqdcFSYVLQ 134
Cdd:cd03256   14 KKALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVEPTS---GSVLIDGtdinklkgkalRQLRRQ-----IGMIFQ 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 135 SDTLLSSLTVRET-----LHYTALL-AIRRGNPGSFQKKVEAVMAELSLSHVADRLIGNyslggISTGERRRVSIAAQLL 208
Cdd:cd03256   86 QFNLIERLSVLENvlsgrLGRRSTWrSLFGLFPKEEKQRALAALERVGLLDKAYQRADQ-----LSGGQQQRVAIARALM 160
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 530367936 209 QDPKVMLFDEPTTGLDCMTANQIVVLLVELAR-RNRIVVLTIHQPrsELF-QLFDKIAILSFGELIFCGTPAE 279
Cdd:cd03256  161 QQPKLILADEPVASLDPASSRQVMDLLKRINReEGITVIVSLHQV--DLArEYADRIVGLKDGRIVFDGPPAE 231
ABC_NikE_OppD_transporters cd03257
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ...
61-249 3.07e-26

ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.


Pssm-ID: 213224 [Multi-domain]  Cd Length: 228  Bit Score: 106.82  E-value: 3.07e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  61 RQQWTRQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGrLGRAGTflGEVYVNGR---ALRREQFQDC---FSYVLQ 134
Cdd:cd03257   13 TGGGSVKALDDVSFSIKKGETLGLVGESGSGKSTLARAILG-LLKPTS--GSIIFDGKdllKLSRRLRKIRrkeIQMVFQ 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 135 sDTLLS---SLTVRETLhyTALLAIRRGNPGSFQKKvEAVMAELSLSHVADRLIGNY--SLGGistGERRRVSIAAQLLQ 209
Cdd:cd03257   90 -DPMSSlnpRMTIGEQI--AEPLRIHGKLSKKEARK-EAVLLLLVGVGLPEEVLNRYphELSG---GQRQRVAIARALAL 162
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 530367936 210 DPKVMLFDEPTTGLDCMTANQIVVLLVELARRNRIVVLTI 249
Cdd:cd03257  163 NPKLLIADEPTSALDVSVQAQILDLLKKLQEELGLTLLFI 202
ABC_TM1139_LivF_branched cd03224
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ...
67-282 5.81e-26

ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.


Pssm-ID: 213191 [Multi-domain]  Cd Length: 222  Bit Score: 105.98  E-value: 5.81e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  67 QILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGtflGEVYVNGRALRR----EQFQDCFSYVLQSDTLLSSL 142
Cdd:cd03224   14 QILFGVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPRS---GSIRFDGRDITGlpphERARAGIGYVPEGRRIFPEL 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 143 TVRETLhytaLLAIRRGNPGSFQKKVEAVMAELS-LSHVADRLIGNyslggISTGERRRVSIAAQLLQDPKVMLFDEPTT 221
Cdd:cd03224   91 TVEENL----LLGAYARRRAKRKARLERVYELFPrLKERRKQLAGT-----LSGGEQQMLAIARALMSRPKLLLLDEPSE 161
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 530367936 222 GLDCMTANQIVVLLVELARRnRIVVLTIHQPRSELFQLFDKIAILSFGELIFCGTPAEMLD 282
Cdd:cd03224  162 GLAPKIVEEIFEAIRELRDE-GVTILLVEQNARFALEIADRAYVLERGRVVLEGTAAELLA 221
ABC_ModC_molybdenum_transporter cd03297
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ...
69-275 1.03e-25

ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213264 [Multi-domain]  Cd Length: 214  Bit Score: 105.07  E-value: 1.03e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  69 LKDVSL---YVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGtflGEVYVNGRALRREQFQDCFS-------YVLQSDTL 138
Cdd:cd03297   10 LPDFTLkidFDLNEEVTGIFGASGAGKSTLLRCIAGLEKPDG---GTIVLNGTVLFDSRKKINLPpqqrkigLVFQQYAL 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 139 LSSLTVRETLHYtallAIRRGNPGSFQKKVEAVMAELSLSHVADRlignySLGGISTGERRRVSIAAQLLQDPKVMLFDE 218
Cdd:cd03297   87 FPHLNVRENLAF----GLKRKRNREDRISVDELLDLLGLDHLLNR-----YPAQLSGGEKQRVALARALAAQPELLLLDE 157
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 530367936 219 PTTGLDCMTANQIVVLLVELARRNRIVVLTIHQPRSELFQLFDKIAILSFGELIFCG 275
Cdd:cd03297  158 PFSALDRALRLQLLPELKQIKKNLNIPVIFVTHDLSEAEYLADRIVVMEDGRLQYIG 214
YbbA COG4181
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase ...
68-253 4.18e-25

Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443338 [Multi-domain]  Cd Length: 233  Bit Score: 103.67  E-value: 4.18e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  68 ILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGrLGRAGTflGEVYVNGR-----------ALRREQfqdcFSYVLQSD 136
Cdd:COG4181   27 ILKGISLEVEAGESVAIVGASGSGKSTLLGLLAG-LDRPTS--GTVRLAGQdlfaldedaraRLRARH----VGFVFQSF 99
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 137 TLLSSLTVREtlhYTALLAIRRGNPGSFQkKVEAVMAELSLSHvadRLiGNYSlGGISTGERRRVSIAAQLLQDPKVMLF 216
Cdd:COG4181  100 QLLPTLTALE---NVMLPLELAGRRDARA-RARALLERVGLGH---RL-DHYP-AQLSGGEQQRVALARAFATEPAILFA 170
                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 530367936 217 DEPTTGLDCMTANQIVVLLVELARRNRI-VVLTIHQPR 253
Cdd:COG4181  171 DEPTGNLDAATGEQIIDLLFELNRERGTtLVLVTHDPA 208
ABC_NatA_sodium_exporter cd03266
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ...
67-275 7.95e-25

ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.


Pssm-ID: 213233 [Multi-domain]  Cd Length: 218  Bit Score: 102.45  E-value: 7.95e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  67 QILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLgRAGTflGEVYVNGRALRREQFQDC--FSYVLQSDTLLSSLTV 144
Cdd:cd03266   19 QAVDGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLL-EPDA--GFATVDGFDVVKEPAEARrrLGFVSDSTGLYDRLTA 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 145 RETLHYTALLairRG-NPGSFQKKVEAVMAELSLSHVADRlignySLGGISTGERRRVSIAAQLLQDPKVMLFDEPTTGL 223
Cdd:cd03266   96 RENLEYFAGL---YGlKGDELTARLEELADRLGMEELLDR-----RVGGFSTGMRQKVAIARALVHDPPVLLLDEPTTGL 167
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 530367936 224 DCMTANQIVVLLVELARRNRIVVLTIHQpRSELFQLFDKIAILSFGELIFCG 275
Cdd:cd03266  168 DVMATRALREFIRQLRALGKCILFSTHI-MQEVERLCDRVVVLHRGRVVYEG 218
ABC_Class3 cd03229
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ...
66-270 8.40e-25

ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213196 [Multi-domain]  Cd Length: 178  Bit Score: 101.11  E-value: 8.40e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  66 RQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGtflGEVYVNGRAL-----RREQFQDCFSYVLQSDTLLS 140
Cdd:cd03229   13 KTVLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEPDS---GSILIDGEDLtdledELPPLRRRIGMVFQDFALFP 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 141 SLTVRETLHYtallairrgnpgsfqkkveavmaelslshvadrlignyslgGISTGERRRVSIAAQLLQDPKVMLFDEPT 220
Cdd:cd03229   90 HLTVLENIAL-----------------------------------------GLSGGQQQRVALARALAMDPDVLLLDEPT 128
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 530367936 221 TGLDCMTANQIVVLLVELARRNRI-VVLTIHQPRsELFQLFDKIAILSFGE 270
Cdd:cd03229  129 SALDPITRREVRALLKSLQAQLGItVVLVTHDLD-EAARLADRVVVLRDGK 178
hmuV PRK13548
hemin importer ATP-binding subunit; Provisional
66-281 1.25e-24

hemin importer ATP-binding subunit; Provisional


Pssm-ID: 237422 [Multi-domain]  Cd Length: 258  Bit Score: 102.93  E-value: 1.25e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  66 RQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLgRAGTflGEVYVNGRAL----------RREqfqdcfsyVL-Q 134
Cdd:PRK13548  15 RTLLDDVSLTLRPGEVVAILGPNGAGKSTLLRALSGEL-SPDS--GEVRLNGRPLadwspaelarRRA--------VLpQ 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 135 SDTLLSSLTVRETLhytAL-LAIRRGNPGSFQKKVEAVMAELSLSHVADRLignY-SLGGistGERRRVSIA---AQLLQ 209
Cdd:PRK13548  84 HSSLSFPFTVEEVV---AMgRAPHGLSRAEDDALVAAALAQVDLAHLAGRD---YpQLSG---GEQQRVQLArvlAQLWE 154
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 210 D---PKVMLFDEPTTGLDcmTANQIVVL--LVELARRNR---IVVLtiHqprsELFQ--LF-DKIAILSFGELIFCGTPA 278
Cdd:PRK13548 155 PdgpPRWLLLDEPTSALD--LAHQHHVLrlARQLAHERGlavIVVL--H----DLNLaaRYaDRIVLLHQGRLVADGTPA 226

                 ...
gi 530367936 279 EML 281
Cdd:PRK13548 227 EVL 229
ModF COG1119
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ...
66-281 1.64e-24

ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];


Pssm-ID: 440736 [Multi-domain]  Cd Length: 250  Bit Score: 102.47  E-value: 1.64e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  66 RQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLgrAGTFLGEVYVNGRALRREQFQD------CFSYVLQsDTLL 139
Cdd:COG1119   16 KTILDDISWTVKPGEHWAILGPNGAGKSTLLSLITGDL--PPTYGNDVRLFGERRGGEDVWElrkrigLVSPALQ-LRFP 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 140 SSLTVRETL------------HYTALLairrgnpgsfQKKVEAVMAELSLSHVADRLIGNyslggISTGERRRVSIAAQL 207
Cdd:COG1119   93 RDETVLDVVlsgffdsiglyrEPTDEQ----------RERARELLELLGLAHLADRPFGT-----LSQGEQRRVLIARAL 157
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 530367936 208 LQDPKVMLFDEPTTGLDCMTANQIVVLLVELARRNRIVVLTI-HQPrSELFQLFDKIAILSFGELIFCGTPAEML 281
Cdd:COG1119  158 VKDPELLILDEPTAGLDLGARELLLALLDKLAAEGAPTLVLVtHHV-EEIPPGITHVLLLKDGRVVAAGPKEEVL 231
PQQ_ABC_ATP TIGR03864
ABC transporter, ATP-binding subunit, PQQ-dependent alcohol dehydrogenase system; Members of ...
66-281 2.00e-24

ABC transporter, ATP-binding subunit, PQQ-dependent alcohol dehydrogenase system; Members of this protein family are the ATP-binding subunit of an ABC transporter system that is associated with PQQ biosynthesis and PQQ-dependent alcohol dehydrogenases. While this family shows homology to several efflux ABC transporter subunits, the presence of a periplasmic substrate-binding protein and association with systems for catabolism of alcohols suggests a role in import rather than detoxification. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 274822 [Multi-domain]  Cd Length: 236  Bit Score: 101.98  E-value: 2.00e-24
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936   66 RQILKDVSLYVESGQIMCILGSSGSGKTTLLdAMSGRLGRAGTflGEVYVNGRALRREQFQDCFSY--VLQSDTLLSSLT 143
Cdd:TIGR03864  14 RRALDDVSFTVRPGRFVALLGPNGAGKSTLF-SLLTRLYVAQS--GQISVAGHDLRRAPRAALARLgvVFQQPTLDLDLS 90
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  144 VRETLHYTALL-AIRRGNPgsfQKKVEAVMAELSLSHVADRLIGnySLGGistGERRRVSIAAQLLQDPKVMLFDEPTTG 222
Cdd:TIGR03864  91 VRQNLRYHAALhGLSRAEA---RARIAELLARLGLAERADDKVR--ELNG---GHRRRVEIARALLHRPALLLLDEPTVG 162
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 530367936  223 LDCMTANQIVVLLVELARRNRIVVL-TIHqprselfqLFDKIA------ILSFGELIFCGTPAEML 281
Cdd:TIGR03864 163 LDPASRAAITAHVRALARDQGLSVLwATH--------LVDEIEasdrlvVLHRGRVLADGAAAELR 220
ABCC_MRP_Like cd03228
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ...
66-270 3.52e-24

ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213195 [Multi-domain]  Cd Length: 171  Bit Score: 99.38  E-value: 3.52e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  66 RQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGrlgragtFL----GEVYVNGRALR---REQFQDCFSYVLQsDTL 138
Cdd:cd03228   15 KPVLKDVSLTIKPGEKVAIVGPSGSGKSTLLKLLLR-------LYdptsGEILIDGVDLRdldLESLRKNIAYVPQ-DPF 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 139 LSSLTVRETLhytallairrgnpgsfqkkveavmaelslshvadrlignyslggISTGERRRVSIAAQLLQDPKVMLFDE 218
Cdd:cd03228   87 LFSGTIRENI--------------------------------------------LSGGQRQRIAIARALLRDPPILILDE 122
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 530367936 219 PTTGLDCMTANQIVVLLVELaRRNRIVVLTIHqpRSELFQLFDKIAILSFGE 270
Cdd:cd03228  123 ATSALDPETEALILEALRAL-AKGKTVIVIAH--RLSTIRDADRIIVLDDGR 171
SunT COG2274
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ...
68-281 7.41e-24

ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];


Pssm-ID: 441875 [Multi-domain]  Cd Length: 711  Bit Score: 106.07  E-value: 7.41e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  68 ILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGrlgragtFL----GEVYVNGRALR---REQFQDCFSYVLQSDTLLS 140
Cdd:COG2274  490 VLDNISLTIKPGERVAIVGRSGSGKSTLLKLLLG-------LYeptsGRILIDGIDLRqidPASLRRQIGVVLQDVFLFS 562
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 141 SlTVRETlhytallaIRRGNPGSFQKKVEAVMAELSLSHVADRLIGNYSL------GGISTGERRRVSIAAQLLQDPKVM 214
Cdd:COG2274  563 G-TIREN--------ITLGDPDATDEEIIEAARLAGLHDFIEALPMGYDTvvgeggSNLSGGQRQRLAIARALLRNPRIL 633
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 530367936 215 LFDEPTTGLDCMTANQIVVLLVELArRNRIVVLTIHqpRSELFQLFDKIAILSFGELIFCGTPAEML 281
Cdd:COG2274  634 ILDEATSALDAETEAIILENLRRLL-KGRTVIIIAH--RLSTIRLADRIIVLDKGRIVEDGTHEELL 697
PotA COG3842
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ...
67-279 8.86e-24

ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443052 [Multi-domain]  Cd Length: 353  Bit Score: 102.87  E-value: 8.86e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  67 QILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGrlgragtFL----GEVYVNGRAL------RREqfqdcFSYVLQSD 136
Cdd:COG3842   19 TALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAG-------FEtpdsGRILLDGRDVtglppeKRN-----VGMVFQDY 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 137 TLLSSLTVRETLHYTalLAIRRGNPGSFQKKVEAVMAELSLSHVADRLIGNyslggISTGERRRVSIAAQLLQDPKVMLF 216
Cdd:COG3842   87 ALFPHLTVAENVAFG--LRMRGVPKAEIRARVAELLELVGLEGLADRYPHQ-----LSGGQQQRVALARALAPEPRVLLL 159
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 530367936 217 DEPTTGLDCMTANQIVVLLVELARRNRIVVLTI-HQpRSELFQLFDKIAILSFGELIFCGTPAE 279
Cdd:COG3842  160 DEPLSALDAKLREEMREELRRLQRELGITFIYVtHD-QEEALALADRIAVMNDGRIEQVGTPEE 222
LolD_lipo_ex TIGR02211
lipoprotein releasing system, ATP-binding protein; This model represents LolD, a member of the ...
67-253 1.92e-23

lipoprotein releasing system, ATP-binding protein; This model represents LolD, a member of the ABC transporter family (pfam00005). LolD is involved in localization of lipoproteins in some bacteria. It works with a transmembrane protein LolC, which in some species is a paralogous pair LolC and LolE. Depending on whether the residue immediately following the new, modified N-terminal Cys residue, the nascent lipoprotein may be carried further by LolA and LolB to the outer membrane, or remain at the inner membrane. The top scoring proteins excluded by this model include homologs from the archaeal genus Methanosarcina. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 131266 [Multi-domain]  Cd Length: 221  Bit Score: 98.58  E-value: 1.92e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936   67 QILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGrLGRAGTflGEVYVNGR-----------ALRREQFqdcfSYVLQS 135
Cdd:TIGR02211  19 RVLKGVSLSIGKGEIVAIVGSSGSGKSTLLHLLGG-LDNPTS--GEVLFNGQslsklssneraKLRNKKL----GFIYQF 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  136 DTLLSSLTVRETLHYTALlaIRRGNPGSFQKKVEAVMAELSLSHvadRLigNYSLGGISTGERRRVSIAAQLLQDPKVML 215
Cdd:TIGR02211  92 HHLLPDFTALENVAMPLL--IGKKSVKEAKERAYEMLEKVGLEH---RI--NHRPSELSGGERQRVAIARALVNQPSLVL 164
                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 530367936  216 FDEPTTGLDCMTANQIVVLLVELARRNRI-VVLTIHQPR 253
Cdd:TIGR02211 165 ADEPTGNLDNNNAKIIFDLMLELNRELNTsFLVVTHDLE 203
ABC_Pro_Gly_Betaine cd03294
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ...
69-287 1.98e-23

ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213261 [Multi-domain]  Cd Length: 269  Bit Score: 100.03  E-value: 1.98e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  69 LKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGtflGEVYVNG-----------RALRREQFqdcfSYVLQSDT 137
Cdd:cd03294   40 VNDVSLDVREGEIFVIMGLSGSGKSTLLRCINRLIEPTS---GKVLIDGqdiaamsrkelRELRRKKI----SMVFQSFA 112
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 138 LLSSLTVRETLHYTalLAIRRGNPGSFQKKVEAVMAELSLSHVADRLIGNyslggISTGERRRVSIAAQLLQDPKVMLFD 217
Cdd:cd03294  113 LLPHRTVLENVAFG--LEVQGVPRAEREERAAEALELVGLEGWEHKYPDE-----LSGGMQQRVGLARALAVDPDILLMD 185
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 218 EPTTGLDCMTANQIVVLLVEL-ARRNRIVVLTIHQPrSELFQLFDKIAILSFGELIFCGTPAEML---------DFFNDC 287
Cdd:cd03294  186 EAFSALDPLIRREMQDELLRLqAELQKTIVFITHDL-DEALRLGDRIAIMKDGRLVQVGTPEEILtnpandyvrEFFRGV 264
ModC COG4148
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ...
71-281 2.35e-23

ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis


Pssm-ID: 443319 [Multi-domain]  Cd Length: 358  Bit Score: 101.72  E-value: 2.35e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  71 DVSLYVESGQIMCILGSSGSGKTTLLDAMSGrLGRAGTflGEVYVNGRAL---RREQF----QDCFSYVLQSDTLLSSLT 143
Cdd:COG4148   17 DVDFTLPGRGVTALFGPSGSGKTTLLRAIAG-LERPDS--GRIRLGGEVLqdsARGIFlpphRRRIGYVFQEARLFPHLS 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 144 VRETLHYtallAIRRGNPGSFQKKVEAVMAELSLSHVADRLIGNyslggISTGERRRVSIAAQLLQDPKVMLFDEPTTGL 223
Cdd:COG4148   94 VRGNLLY----GRKRAPRAERRISFDEVVELLGIGHLLDRRPAT-----LSGGERQRVAIGRALLSSPRLLLMDEPLAAL 164
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 530367936 224 DCMTANQIVVLLVELARRNRIVVLTI-HQPRsELFQLFDKIAILSFGELIFCGTPAEML 281
Cdd:COG4148  165 DLARKAEILPYLERLRDELDIPILYVsHSLD-EVARLADHVVLLEQGRVVASGPLAEVL 222
ABC_OpuCA_Osmoprotection cd03295
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ...
69-281 3.57e-23

ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213262 [Multi-domain]  Cd Length: 242  Bit Score: 98.53  E-value: 3.57e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  69 LKDVSLYVESGQIMCILGSSGSGKTTLLdAMSGRLGRAGTflGEVYVNGR--------ALRREqfqdcFSYVLQSDTLLS 140
Cdd:cd03295   17 VNNLNLEIAKGEFLVLIGPSGSGKTTTM-KMINRLIEPTS--GEIFIDGEdireqdpvELRRK-----IGYVIQQIGLFP 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 141 SLTVRETLhyTALLAIRRGNPGSFQKKVEAVMAELSL--SHVADRlignYSlGGISTGERRRVSIAAQLLQDPKVMLFDE 218
Cdd:cd03295   89 HMTVEENI--ALVPKLLKWPKEKIRERADELLALVGLdpAEFADR----YP-HELSGGQQQRVGVARALAADPPLLLMDE 161
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 530367936 219 PTTGLDCMTANQIVVLLVELARR-NRIVVLTIHQpRSELFQLFDKIAILSFGELIFCGTPAEML 281
Cdd:cd03295  162 PFGALDPITRDQLQEEFKRLQQElGKTIVFVTHD-IDEAFRLADRIAIMKNGEIVQVGTPDEIL 224
FtsE COG2884
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
66-250 6.61e-23

Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442130 [Multi-domain]  Cd Length: 223  Bit Score: 97.05  E-value: 6.61e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  66 RQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSG--RLGRagtflGEVYVNGR---ALRREQ-----------FQDCf 129
Cdd:COG2884   15 REALSDVSLEIEKGEFVFLTGPSGAGKSTLLKLLYGeeRPTS-----GQVLVNGQdlsRLKRREipylrrrigvvFQDF- 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 130 syvlqsdTLLSSLTVRETLHYtALLAIRRgNPGSFQKKVEAVMAELSLSHVADRLIGNyslggISTGERRRVSIAAQLLQ 209
Cdd:COG2884   89 -------RLLPDRTVYENVAL-PLRVTGK-SRKEIRRRVREVLDLVGLSDKAKALPHE-----LSGGEQQRVAIARALVN 154
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 530367936 210 DPKVMLFDEPTTGLDCMTANQIVVLLVELARRNRIVVLTIH 250
Cdd:COG2884  155 RPELLLADEPTGNLDPETSWEIMELLEEINRRGTTVLIATH 195
MalK COG3839
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ...
67-282 1.20e-22

ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];


Pssm-ID: 443050 [Multi-domain]  Cd Length: 352  Bit Score: 99.38  E-value: 1.20e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  67 QILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGrlgragtfL-----GEVYVNGR------ALRREqfqdcFSYVLQS 135
Cdd:COG3839   17 EALKDIDLDIEDGEFLVLLGPSGCGKSTLLRMIAG--------LedptsGEILIGGRdvtdlpPKDRN-----IAMVFQS 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 136 DTLLSSLTVRETLhytAL-LAIRRGNPGSFQKKVEAVMAELSLSHVADRLIGNysLGGistGERRRVSIAAQLLQDPKVM 214
Cdd:COG3839   84 YALYPHMTVYENI---AFpLKLRKVPKAEIDRRVREAAELLGLEDLLDRKPKQ--LSG---GQRQRVALGRALVREPKVF 155
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 215 LFDEPTTGLDCMTANQIVVLLVELARRNRIVVL--TiHQPrSELFQLFDKIAILSFGELIFCGTPAEMLD 282
Cdd:COG3839  156 LLDEPLSNLDAKLRVEMRAEIKRLHRRLGTTTIyvT-HDQ-VEAMTLADRIAVMNDGRIQQVGTPEELYD 223
YhaQ COG4152
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
65-279 1.80e-22

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443322 [Multi-domain]  Cd Length: 298  Bit Score: 97.87  E-value: 1.80e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  65 TRQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLgRAGTflGEVYVNGRALRREQfQDCFSYVLQSDTLLSSLTV 144
Cdd:COG4152   13 DKTAVDDVSFTVPKGEIFGLLGPNGAGKTTTIRIILGIL-APDS--GEVLWDGEPLDPED-RRRIGYLPEERGLYPKMKV 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 145 RETLHYtalLAIRRG-NPGSFQKKVEAVMAELSLSHVADRLIGNYSLGgistgERRRVSIAAQLLQDPKVMLFDEPTTGL 223
Cdd:COG4152   89 GEQLVY---LARLKGlSKAEAKRRADEWLERLGLGDRANKKVEELSKG-----NQQKVQLIAALLHDPELLILDEPFSGL 160
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 530367936 224 DCMTANQIVVLLVELARRNRIVVLTIHQPRS-ElfQLFDKIAILSFGELIFCGTPAE 279
Cdd:COG4152  161 DPVNVELLKDVIRELAAKGTTVIFSSHQMELvE--ELCDRIVIINKGRKVLSGSVDE 215
PRK10895 PRK10895
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
66-281 2.50e-22

lipopolysaccharide ABC transporter ATP-binding protein; Provisional


Pssm-ID: 182817 [Multi-domain]  Cd Length: 241  Bit Score: 96.12  E-value: 2.50e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  66 RQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGR-AGTFLGE------VYVNGRALRReqfqdcFSYVLQSDTL 138
Cdd:PRK10895  16 RRVVEDVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRdAGNIIIDdedislLPLHARARRG------IGYLPQEASI 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 139 LSSLTVRETLhyTALLAIRRG-NPGSFQKKVEAVMAELSLSHVADrlignySLG-GISTGERRRVSIAAQLLQDPKVMLF 216
Cdd:PRK10895  90 FRRLSVYDNL--MAVLQIRDDlSAEQREDRANELMEEFHIEHLRD------SMGqSLSGGERRRVEIARALAANPKFILL 161
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 530367936 217 DEPTTGLDCMTANQIVVLLVELARRNRIVVLTIHQPRsELFQLFDKIAILSFGELIFCGTPAEML 281
Cdd:PRK10895 162 DEPFAGVDPISVIDIKRIIEHLRDSGLGVLITDHNVR-ETLAVCERAYIVSQGHLIAHGTPTEIL 225
ABCC_Glucan_exporter_like cd03254
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ...
66-282 2.81e-22

ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213221 [Multi-domain]  Cd Length: 229  Bit Score: 95.76  E-value: 2.81e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  66 RQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGtflGEVYVNG---RALRREQFQDCFSYVLQsDTLLSSL 142
Cdd:cd03254   16 KPVLKDINFSIKPGETVAIVGPTGAGKTTLINLLMRFYDPQK---GQILIDGidiRDISRKSLRSMIGVVLQ-DTFLFSG 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 143 TVRETlhytallaIRRGNPGSFQKKVEAVMAELSLSHVADRLIGNY------SLGGISTGERRRVSIAAQLLQDPKVMLF 216
Cdd:cd03254   92 TIMEN--------IRLGRPNATDEEVIEAAKEAGAHDFIMKLPNGYdtvlgeNGGNLSQGERQLLAIARAMLRDPKILIL 163
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 530367936 217 DEPTTGLDCMTANQIVVLLVELaRRNRIVVLTIHQPRSELFQlfDKIAILSFGELIFCGTPAEMLD 282
Cdd:cd03254  164 DEATSNIDTETEKLIQEALEKL-MKGRTSIIIAHRLSTIKNA--DKILVLDDGKIIEEGTHDELLA 226
ccmA TIGR01189
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ...
59-253 5.39e-21

heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]


Pssm-ID: 273491 [Multi-domain]  Cd Length: 198  Bit Score: 90.88  E-value: 5.39e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936   59 SCRQQWtRQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGtflGEVYVNGRAL--RREQFQDCFSYVLQSD 136
Cdd:TIGR01189   7 ACSRGE-RMLFEGLSFTLNAGEALQVTGPNGIGKTTLLRILAGLLRPDS---GEVRWNGTPLaeQRDEPHENILYLGHLP 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  137 TLLSSLTVRETLHYTALLAirrgnpGSFQKKVEAVMAELSLSHVADRLIGNyslggISTGERRRVSIAAQLLQDPKVMLF 216
Cdd:TIGR01189  83 GLKPELSALENLHFWAAIH------GGAQRTIEDALAAVGLTGFEDLPAAQ-----LSAGQQRRLALARLWLSRRPLWIL 151
                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 530367936  217 DEPTTGLDCMTANQIVVLLVELARRNRIVVLTIHQPR 253
Cdd:TIGR01189 152 DEPTTALDKAGVALLAGLLRAHLARGGIVLLTTHQDL 188
ABC_MalK_N cd03301
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ...
68-271 6.36e-21

The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.


Pssm-ID: 213268 [Multi-domain]  Cd Length: 213  Bit Score: 91.16  E-value: 6.36e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  68 ILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGtflGEVYVNGRALRREQFQD-CFSYVLQSDTLLSSLTVRE 146
Cdd:cd03301   15 ALDDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPTS---GRIYIGGRDVTDLPPKDrDIAMVFQNYALYPHMTVYD 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 147 TLHYTalLAIRRGNPGSFQKKVEAVMAELSLSHVADRLIGNyslggISTGERRRVSIAAQLLQDPKVMLFDEPTTGLDCM 226
Cdd:cd03301   92 NIAFG--LKLRKVPKDEIDERVREVAELLQIEHLLDRKPKQ-----LSGGQRQRVALGRAIVREPKVFLMDEPLSNLDAK 164
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 530367936 227 TANQIVVLLVELARRNRIVVLTIHQPRSELFQLFDKIAILSFGEL 271
Cdd:cd03301  165 LRVQMRAELKRLQQRLGTTTIYVTHDQVEAMTMADRIAVMNDGQI 209
GlnQ COG1126
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and ...
67-282 1.56e-20

ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440743 [Multi-domain]  Cd Length: 239  Bit Score: 90.82  E-value: 1.56e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  67 QILKDVSLYVESGQIMCILGSSGSGKTTLLdamsgrlgRAGTFL-----GEVYVNG----------RALRREqfqdcFSY 131
Cdd:COG1126   15 EVLKGISLDVEKGEVVVIIGPSGSGKSTLL--------RCINLLeepdsGTITVDGedltdskkdiNKLRRK-----VGM 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 132 VLQSDTLLSSLTVRE--TLhytALLAIRRgnpgsfQKKVEAV---MAELS---LSHVADRlignY--SLGGistGERRRV 201
Cdd:COG1126   82 VFQQFNLFPHLTVLEnvTL---APIKVKK------MSKAEAEeraMELLErvgLADKADA----YpaQLSG---GQQQRV 145
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 202 SIAAQLLQDPKVMLFDEPTTGLDCMTANQIVVLLVELARRNR-IVVLTiHqprsEL-F--QLFDKIAILSFGELIFCGTP 277
Cdd:COG1126  146 AIARALAMEPKVMLFDEPTSALDPELVGEVLDVMRDLAKEGMtMVVVT-H----EMgFarEVADRVVFMDGGRIVEEGPP 220

                 ....*
gi 530367936 278 AEMLD 282
Cdd:COG1126  221 EEFFE 225
ABCC_ATM1_transporter cd03253
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ...
66-282 1.60e-20

ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213220 [Multi-domain]  Cd Length: 236  Bit Score: 90.75  E-value: 1.60e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  66 RQILKDVSLYVESGQIMCILGSSGSGKTTLL-------DAMSGRlgragtflgeVYVNGRALRR---EQFQDCFSYVLQs 135
Cdd:cd03253   14 RPVLKDVSFTIPAGKKVAIVGPSGSGKSTILrllfrfyDVSSGS----------ILIDGQDIREvtlDSLRRAIGVVPQ- 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 136 DTLLSSLTVRETlhytallaIRRGNPGSFQKKVEAVmAELSlsHVADRLIG---NYS--LG--G--ISTGERRRVSIAAQ 206
Cdd:cd03253   83 DTVLFNDTIGYN--------IRYGRPDATDEEVIEA-AKAA--QIHDKIMRfpdGYDtiVGerGlkLSGGEKQRVAIARA 151
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 530367936 207 LLQDPKVMLFDEPTTGLDCMTANQIVVLLVELArRNRIVVLTIHQPRSELFQlfDKIAILSFGELIFCGTPAEMLD 282
Cdd:cd03253  152 ILKNPPILLLDEATSALDTHTEREIQAALRDVS-KGRTTIVIAHRLSTIVNA--DKIIVLKDGRIVERGTHEELLA 224
PRK13539 PRK13539
cytochrome c biogenesis protein CcmA; Provisional
66-252 2.36e-20

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 237421 [Multi-domain]  Cd Length: 207  Bit Score: 89.55  E-value: 2.36e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  66 RQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGtflGEVYVNGRALRREQFQDCFSYVLQSDTLLSSLTVR 145
Cdd:PRK13539  15 RVLFSGLSFTLAAGEALVLTGPNGSGKTTLLRLIAGLLPPAA---GTIKLDGGDIDDPDVAEACHYLGHRNAMKPALTVA 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 146 ETLHYTAllAIRRGNPGSfqkkVEAVMAELSLSHVADRLIGNyslggISTGERRRVSIAAQLLQDPKVMLFDEPTTGLDc 225
Cdd:PRK13539  92 ENLEFWA--AFLGGEELD----IAAALEAVGLAPLAHLPFGY-----LSAGQKRRVALARLLVSNRPIWILDEPTAALD- 159
                        170       180
                 ....*....|....*....|....*....
gi 530367936 226 mTANQIVVLLVELARRNR--IVVLTIHQP 252
Cdd:PRK13539 160 -AAAVALFAELIRAHLAQggIVIAATHIP 187
MdlB COG1132
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
66-281 3.05e-20

ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];


Pssm-ID: 440747 [Multi-domain]  Cd Length: 579  Bit Score: 94.46  E-value: 3.05e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  66 RQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGrlgragtFL----GEVYVNG---RALRREQFQDCFSYVLQsDTL 138
Cdd:COG1132  353 RPVLKDISLTIPPGETVALVGPSGSGKSTLVNLLLR-------FYdptsGRILIDGvdiRDLTLESLRRQIGVVPQ-DTF 424
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 139 LSSLTVREtlhytallAIRRGNPGSFQKKVEAVMAELSLSHVADRL-------IGNyslGGI--STGERRRVSIAAQLLQ 209
Cdd:COG1132  425 LFSGTIRE--------NIRYGRPDATDEEVEEAAKAAQAHEFIEALpdgydtvVGE---RGVnlSGGQRQRIAIARALLK 493
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 530367936 210 DPKVMLFDEPTTGLDCMTANQIVVLLVELaRRNRIVVL------TIhqprselfQLFDKIAILSFGELIFCGTPAEML 281
Cdd:COG1132  494 DPPILILDEATSALDTETEALIQEALERL-MKGRTTIViahrlsTI--------RNADRILVLDDGRIVEQGTHEELL 562
ABC_CcmA_heme_exporter cd03231
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ...
60-269 4.30e-20

Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.


Pssm-ID: 213198 [Multi-domain]  Cd Length: 201  Bit Score: 88.70  E-value: 4.30e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  60 CRQQWtRQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGtflGEVYVNGRAL--RREQFQDCFSYVLQSDT 137
Cdd:cd03231    8 CERDG-RALFSGLSFTLAAGEALQVTGPNGSGKTTLLRILAGLSPPLA---GRVLLNGGPLdfQRDSIARGLLYLGHAPG 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 138 LLSSLTVRETLHYTALLAIRRGnpgsfqkkVEAVMAELSLSHVADRLIGNyslggISTGERRRVSIAAQLLQDPKVMLFD 217
Cdd:cd03231   84 IKTTLSVLENLRFWHADHSDEQ--------VEEALARVGLNGFEDRPVAQ-----LSAGQQRRVALARLLLSGRPLWILD 150
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 530367936 218 EPTTGLDCMTANQIVVLLVELARRNRIVVLTIHQPrseLFQLFDKIAILSFG 269
Cdd:cd03231  151 EPTTALDKAGVARFAEAMAGHCARGGMVVLTTHQD---LGLSEAGARELDLG 199
ABC_HisP_GlnQ cd03262
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ...
65-251 4.92e-20

ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.


Pssm-ID: 213229 [Multi-domain]  Cd Length: 213  Bit Score: 88.74  E-value: 4.92e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  65 TRQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSgRLGRAGTflGEVYVNGRAL--RREQFQDCFSY---VLQSDTLL 139
Cdd:cd03262   12 DFHVLKGIDLTVKKGEVVVIIGPSGSGKSTLLRCIN-LLEEPDS--GTIIIDGLKLtdDKKNINELRQKvgmVFQQFNLF 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 140 SSLTVRETLHYtALLAIRRGNPGSFQKKVEAVMAELSLSHVADRLIGNyslggISTGERRRVSIAAQLLQDPKVMLFDEP 219
Cdd:cd03262   89 PHLTVLENITL-APIKVKGMSKAEAEERALELLEKVGLADKADAYPAQ-----LSGGQQQRVAIARALAMNPKVMLFDEP 162
                        170       180       190
                 ....*....|....*....|....*....|..
gi 530367936 220 TTGLDCMTANQIVVLLVELARRNRIVVLTIHQ 251
Cdd:cd03262  163 TSALDPELVGEVLDVMKDLAEEGMTMVVVTHE 194
ABC_putative_ATPase cd03269
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ...
65-275 5.33e-20

ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213236 [Multi-domain]  Cd Length: 210  Bit Score: 88.49  E-value: 5.33e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  65 TRQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMsgrlgrAGTFL---GEVYVNGRALRREQFQDcFSYVLQSDTLLSS 141
Cdd:cd03269   12 RVTALDDISFSVEKGEIFGLLGPNGAGKTTTIRMI------LGIILpdsGEVLFDGKPLDIAARNR-IGYLPEERGLYPK 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 142 LTVRETLHYTALLairRG-NPGSFQKKVEAVMAELSLSHVADRlignySLGGISTGERRRVSIAAQLLQDPKVMLFDEPT 220
Cdd:cd03269   85 MKVIDQLVYLAQL---KGlKKEEARRRIDEWLERLELSEYANK-----RVEELSKGNQQKVQFIAAVIHDPELLILDEPF 156
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 530367936 221 TGLDCMTANQIVVLLVELARRNRIVVLTIHQpRSELFQLFDKIAILSFGELIFCG 275
Cdd:cd03269  157 SGLDPVNVELLKDVIRELARAGKTVILSTHQ-MELVEELCDRVLLLNKGRAVLYG 210
ABC_FtsE cd03292
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ...
69-250 6.65e-20

Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages


Pssm-ID: 213259 [Multi-domain]  Cd Length: 214  Bit Score: 88.23  E-value: 6.65e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  69 LKDVSLYVESGQIMCILGSSGSGKTTLLDAMsgrLGRAGTFLGEVYVNGRA---LRREQ---FQDCFSYVLQSDTLLSSL 142
Cdd:cd03292   17 LDGINISISAGEFVFLVGPSGAGKSTLLKLI---YKEELPTSGTIRVNGQDvsdLRGRAipyLRRKIGVVFQDFRLLPDR 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 143 TVRETLHYTalLAIRRGNPGSFQKKVEAVMAELSLSHVADRLIGnyslgGISTGERRRVSIAAQLLQDPKVMLFDEPTTG 222
Cdd:cd03292   94 NVYENVAFA--LEVTGVPPREIRKRVPAALELVGLSHKHRALPA-----ELSGGEQQRVAIARAIVNSPTILIADEPTGN 166
                        170       180
                 ....*....|....*....|....*...
gi 530367936 223 LDCMTANQIVVLLVELARRNRIVVLTIH 250
Cdd:cd03292  167 LDPDTTWEIMNLLKKINKAGTTVVVATH 194
fecE PRK11231
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
65-281 6.67e-20

Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;


Pssm-ID: 183044 [Multi-domain]  Cd Length: 255  Bit Score: 89.30  E-value: 6.67e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  65 TRQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSgRLGRagTFLGEVYVNGRALRR---EQFQDCFSYVLQSDTLLSS 141
Cdd:PRK11231  14 TKRILNDLSLSLPTGKITALIGPNGCGKSTLLKCFA-RLLT--PQSGTVFLGDKPISMlssRQLARRLALLPQHHLTPEG 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 142 LTVREtlhytaLLAIRRGNPGSF--------QKKVEAVMAELSLSHVADRLIGNyslggISTGERRRVSIAAQLLQDPKV 213
Cdd:PRK11231  91 ITVRE------LVAYGRSPWLSLwgrlsaedNARVNQAMEQTRINHLADRRLTD-----LSGGQRQRAFLAMVLAQDTPV 159
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 530367936 214 MLFDEPTTGLDCMTANQIVVLLVELARRNRIVVLTIHqprsELFQ---LFDKIAILSFGELIFCGTPAEML 281
Cdd:PRK11231 160 VLLDEPTTYLDINHQVELMRLMRELNTQGKTVVTVLH----DLNQasrYCDHLVVLANGHVMAQGTPEEVM 226
ABCC_Hemolysin cd03252
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ...
66-282 7.79e-20

ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.


Pssm-ID: 213219 [Multi-domain]  Cd Length: 237  Bit Score: 88.70  E-value: 7.79e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  66 RQILKDVSLYVESGQIMCILGSSGSGKTTLLD-------AMSGRLGRAGTFLGEVYVNgrALRREqfqdcFSYVLQSDTL 138
Cdd:cd03252   15 PVILDNISLRIKPGEVVGIVGRSGSGKSTLTKliqrfyvPENGRVLVDGHDLALADPA--WLRRQ-----VGVVLQENVL 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 139 LSSlTVRETlhytallaIRRGNPGSFQKKVEAVmAELSLSHV--------ADRLIGNYSLGgISTGERRRVSIAAQLLQD 210
Cdd:cd03252   88 FNR-SIRDN--------IALADPGMSMERVIEA-AKLAGAHDfiselpegYDTIVGEQGAG-LSGGQRQRIAIARALIHN 156
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 530367936 211 PKVMLFDEPTTGLDCMTANQIVVLLVELArRNRIVVLTIHqpRSELFQLFDKIAILSFGELIFCGTPAEMLD 282
Cdd:cd03252  157 PRILIFDEATSALDYESEHAIMRNMHDIC-AGRTVIIIAH--RLSTVKNADRIIVMEKGRIVEQGSHDELLA 225
ABC_CysA_sulfate_importer cd03296
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ...
69-282 8.64e-20

ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213263 [Multi-domain]  Cd Length: 239  Bit Score: 88.55  E-value: 8.64e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  69 LKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGrLGRAGTflGEVYVNGRALRREQFQD-CFSYVLQSDTLLSSLTVRET 147
Cdd:cd03296   18 LDDVSLDIPSGELVALLGPSGSGKTTLLRLIAG-LERPDS--GTILFGGEDATDVPVQErNVGFVFQHYALFRHMTVFDN 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 148 LHYTalLAIR----RGNPGSFQKKVEAVMAELSLSHVADRLIGNyslggISTGERRRVSIAAQLLQDPKVMLFDEPTTGL 223
Cdd:cd03296   95 VAFG--LRVKprseRPPEAEIRAKVHELLKLVQLDWLADRYPAQ-----LSGGQRQRVALARALAVEPKVLLLDEPFGAL 167
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 530367936 224 DCMTANQIVVLLVELARRNRIVVLTIHQPRSELFQLFDKIAILSFGELIFCGTPAEMLD 282
Cdd:cd03296  168 DAKVRKELRRWLRRLHDELHVTTVFVTHDQEEALEVADRVVVMNKGRIEQVGTPDEVYD 226
cbiO TIGR01166
cobalt transport protein ATP-binding subunit; This model describes the ATP binding subunit of ...
67-250 1.03e-19

cobalt transport protein ATP-binding subunit; This model describes the ATP binding subunit of the multisubunit cobalt transporter in bacteria and its equivalents in archaea. The model is restricted to ATP subunit that is a part of the cobalt transporter, which belongs to the ABC transporter superfamily (ATP Binding Cassette). The model excludes ATP binding subunit that are associated with other transporters belonging to ABC transporter superfamily. This superfamily includes two groups, one which catalyze the uptake of small molecules, including ions from the external milieu and the other group which is engaged in the efflux of small molecular weight compounds and ions from within the cell. Energy derived from the hydrolysis of ATP drive the both the process of uptake and efflux. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 130234 [Multi-domain]  Cd Length: 190  Bit Score: 87.09  E-value: 1.03e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936   67 QILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGtflGEVYVNGRAL---------RREQFQdcfsYVLQS-D 136
Cdd:TIGR01166   6 EVLKGLNFAAERGEVLALLGANGAGKSTLLLHLNGLLRPQS---GAVLIDGEPLdysrkglleRRQRVG----LVFQDpD 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  137 TLLSSLTVRETLHYTAL-LAirrGNPGSFQKKVEAVMAELSLSHVADRLIGNyslggISTGERRRVSIAAQLLQDPKVML 215
Cdd:TIGR01166  79 DQLFAADVDQDVAFGPLnLG---LSEAEVERRVREALTAVGASGLRERPTHC-----LSGGEKKRVAIAGAVAMRPDVLL 150
                         170       180       190
                  ....*....|....*....|....*....|....*
gi 530367936  216 FDEPTTGLDCMTANQIVVLLVELARRNRIVVLTIH 250
Cdd:TIGR01166 151 LDEPTAGLDPAGREQMLAILRRLRAEGMTVVISTH 185
ArtP COG4161
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];
67-239 1.10e-19

ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443326 [Multi-domain]  Cd Length: 242  Bit Score: 88.53  E-value: 1.10e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  67 QILKDVSLYVESGQIMCILGSSGSGKTTLLDAM-------SGRLGRAG-TFLGEVYVN---GRALRREqfqdcFSYVLQS 135
Cdd:COG4161   16 QALFDINLECPSGETLVLLGPSGAGKSSLLRVLnlletpdSGQLNIAGhQFDFSQKPSekaIRLLRQK-----VGMVFQQ 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 136 DTLLSSLTVRETLhYTALLAIRRGNPGSFQKKVEAVMAELSLSHVADRlignYSLGgISTGERRRVSIAAQLLQDPKVML 215
Cdd:COG4161   91 YNLWPHLTVMENL-IEAPCKVLGLSKEQAREKAMKLLARLRLTDKADR----FPLH-LSGGQQQRVAIARALMMEPQVLL 164
                        170       180
                 ....*....|....*....|....
gi 530367936 216 FDEPTTGLDCMTANQIVVLLVELA 239
Cdd:COG4161  165 FDEPTAALDPEITAQVVEIIRELS 188
CydD TIGR02857
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ...
65-266 1.21e-19

thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD


Pssm-ID: 274323 [Multi-domain]  Cd Length: 529  Bit Score: 92.35  E-value: 1.21e-19
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936   65 TRQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGrLGRAGTflGEVYVNGRALR---REQFQDCFSYVLQSDTLLSS 141
Cdd:TIGR02857 334 RRPALRPVSFTVPPGERVALVGPSGAGKSTLLNLLLG-FVDPTE--GSIAVNGVPLAdadADSWRDQIAWVPQHPFLFAG 410
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  142 lTVRETLhytaLLAIRRGNPGSFQKKVEAV-----MAELSLSHvaDRLIGNYSlGGISTGERRRVSIAAQLLQDPKVMLF 216
Cdd:TIGR02857 411 -TIAENI----RLARPDASDAEIREALERAgldefVAALPQGL--DTPIGEGG-AGLSGGQAQRLALARAFLRDAPLLLL 482
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 530367936  217 DEPTTGLDCMTANQIVVLLVELArRNRIVVLTIHQPrsELFQLFDKIAIL 266
Cdd:TIGR02857 483 DEPTAHLDAETEAEVLEALRALA-QGRTVLLVTHRL--ALAALADRIVVL 529
cbiO PRK13636
cobalt transporter ATP-binding subunit; Provisional
69-281 1.51e-19

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184196 [Multi-domain]  Cd Length: 283  Bit Score: 89.14  E-value: 1.51e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  69 LKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGtflGEVYVNGRALRRE-----QFQDCFSYVLQS-DTLLSSL 142
Cdd:PRK13636  22 LKGININIKKGEVTAILGGNGAGKSTLFQNLNGILKPSS---GRILFDGKPIDYSrkglmKLRESVGMVFQDpDNQLFSA 98
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 143 TVRETLHYTALlaiRRGNP-GSFQKKVEAVMAELSLSHVADRlignySLGGISTGERRRVSIAAQLLQDPKVMLFDEPTT 221
Cdd:PRK13636  99 SVYQDVSFGAV---NLKLPeDEVRKRVDNALKRTGIEHLKDK-----PTHCLSFGQKKRVAIAGVLVMEPKVLVLDEPTA 170
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 530367936 222 GLDCMTANQIVVLLVELARRNRIVVLtIHQPRSELFQLF-DKIAILSFGELIFCGTPAEML 281
Cdd:PRK13636 171 GLDPMGVSEIMKLLVEMQKELGLTII-IATHDIDIVPLYcDNVFVMKEGRVILQGNPKEVF 230
lolD PRK11629
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
68-241 1.64e-19

lipoprotein-releasing ABC transporter ATP-binding protein LolD;


Pssm-ID: 183244 [Multi-domain]  Cd Length: 233  Bit Score: 87.56  E-value: 1.64e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  68 ILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGtflGEVYVNGRAL-------RREQFQDCFSYVLQSDTLLS 140
Cdd:PRK11629  24 VLHNVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTS---GDVIFNGQPMsklssaaKAELRNQKLGFIYQFHHLLP 100
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 141 SLTVRETLHYTALlaIRRGNPGSFQKKVEAVMAELSLSHVAdrligNYSLGGISTGERRRVSIAAQLLQDPKVMLFDEPT 220
Cdd:PRK11629 101 DFTALENVAMPLL--IGKKKPAEINSRALEMLAAVGLEHRA-----NHRPSELSGGERQRVAIARALVNNPRLVLADEPT 173
                        170       180
                 ....*....|....*....|.
gi 530367936 221 TGLDCMTANQIVVLLVELARR 241
Cdd:PRK11629 174 GNLDARNADSIFQLLGELNRL 194
cbiO PRK13639
cobalt transporter ATP-binding subunit; Provisional
67-280 2.01e-19

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184199 [Multi-domain]  Cd Length: 275  Bit Score: 88.60  E-value: 2.01e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  67 QILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGtflGEVYVNGRALRRE-----QFQDCFSYVLQ-SDTLLS 140
Cdd:PRK13639  16 EALKGINFKAEKGEMVALLGPNGAGKSTLFLHFNGILKPTS---GEVLIKGEPIKYDkksllEVRKTVGIVFQnPDDQLF 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 141 SLTVRETLHYTALlairrgNPG----SFQKKVEAVMAELSLSHVADRLIGNyslggISTGERRRVSIAAQLLQDPKVMLF 216
Cdd:PRK13639  93 APTVEEDVAFGPL------NLGlskeEVEKRVKEALKAVGMEGFENKPPHH-----LSGGQKKRVAIAGILAMKPEIIVL 161
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 530367936 217 DEPTTGLDCMTANQIVVLLVELARRNRIVVLTIHQprSELFQLF-DKIAILSFGELIFCGTPAEM 280
Cdd:PRK13639 162 DEPTSGLDPMGASQIMKLLYDLNKEGITIIISTHD--VDLVPVYaDKVYVMSDGKIIKEGTPKEV 224
ABCC_MsbA cd03251
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ...
68-282 2.09e-19

ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213218 [Multi-domain]  Cd Length: 234  Bit Score: 87.29  E-value: 2.09e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  68 ILKDVSLYVESGQIMCILGSSGSGKTTLL-------DAMSGRLGRAGTFLGEVYVNgrALRREqfqdcFSYVLQsDTLLS 140
Cdd:cd03251   17 VLRDISLDIPAGETVALVGPSGSGKSTLVnliprfyDVDSGRILIDGHDVRDYTLA--SLRRQ-----IGLVSQ-DVFLF 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 141 SLTVRETlhytallaIRRGNPGSFQKKVEAVmAELSLSH-VADRLIGNY--SLG--GI--STGERRRVSIAAQLLQDPKV 213
Cdd:cd03251   89 NDTVAEN--------IAYGRPGATREEVEEA-ARAANAHeFIMELPEGYdtVIGerGVklSGGQRQRIAIARALLKDPPI 159
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 530367936 214 MLFDEPTTGLDCMTANQIVVLLVELArRNRIVVLTIHqpRSELFQLFDKIAILSFGELIFCGTPAEMLD 282
Cdd:cd03251  160 LILDEATSALDTESERLVQAALERLM-KNRTTFVIAH--RLSTIENADRIVVLEDGKIVERGTHEELLA 225
ABC_PotA_N cd03300
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ...
67-282 2.42e-19

ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213267 [Multi-domain]  Cd Length: 232  Bit Score: 87.29  E-value: 2.42e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  67 QILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGtflGEVYVNGRAL------RREqfqdcFSYVLQSDTLLS 140
Cdd:cd03300   14 VALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTS---GEILLDGKDItnlpphKRP-----VNTVFQNYALFP 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 141 SLTVRETLHYTalLAIRRGNPGSFQKKVEAVMAELSLSHVADRLIGNyslggISTGERRRVSIAAQLLQDPKVMLFDEPT 220
Cdd:cd03300   86 HLTVFENIAFG--LRLKKLPKAEIKERVAEALDLVQLEGYANRKPSQ-----LSGGQQQRVAIARALVNEPKVLLLDEPL 158
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 530367936 221 TGLDCMTANQIVVLLVELARRNRIVVLTIHQPRSELFQLFDKIAILSFGELIFCGTPAEMLD 282
Cdd:cd03300  159 GALDLKLRKDMQLELKRLQKELGITFVFVTHDQEEALTMSDRIAVMNKGKIQQIGTPEEIYE 220
CysA COG1118
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ...
65-282 3.46e-19

ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440735 [Multi-domain]  Cd Length: 348  Bit Score: 89.05  E-value: 3.46e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  65 TRQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGrLGRAGTflGEVYVNGRalrreqfqDCFS----------YVLQ 134
Cdd:COG1118   14 SFTLLDDVSLEIASGELVALLGPSGSGKTTLLRIIAG-LETPDS--GRIVLNGR--------DLFTnlpprerrvgFVFQ 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 135 SDTLLSSLTVRETLHYTalLAIRRGNPGSFQKKVEAVMAELSLSHVADRLIGNyslggISTGERRRVSIAAQLLQDPKVM 214
Cdd:COG1118   83 HYALFPHMTVAENIAFG--LRVRPPSKAEIRARVEELLELVQLEGLADRYPSQ-----LSGGQRQRVALARALAVEPEVL 155
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 530367936 215 LFDEPTTGLDCMTANQIVVLLVELARRNRIVVLTI-HQpRSELFQLFDKIAILSFGELIFCGTPAEMLD 282
Cdd:COG1118  156 LLDEPFGALDAKVRKELRRWLRRLHDELGGTTVFVtHD-QEEALELADRVVVMNQGRIEQVGTPDEVYD 223
ABC_PstB_phosphate_transporter cd03260
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ...
66-272 4.26e-19

ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).


Pssm-ID: 213227 [Multi-domain]  Cd Length: 227  Bit Score: 86.47  E-value: 4.26e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  66 RQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGTFL--GEVYVNGR----------ALRREqfqdcFSYVL 133
Cdd:cd03260   13 KHALKDISLDIPKGEITALIGPSGCGKSTLLRLLNRLNDLIPGAPdeGEVLLDGKdiydldvdvlELRRR-----VGMVF 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 134 QSDTLLSsLTVRETLHYTalLAIRrgnpGSFQKKVEAVMAELSLS------HVADRLIGnyslGGISTGERRRVSIAAQL 207
Cdd:cd03260   88 QKPNPFP-GSIYDNVAYG--LRLH----GIKLKEELDERVEEALRkaalwdEVKDRLHA----LGLSGGQQQRLCLARAL 156
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 530367936 208 LQDPKVMLFDEPTTGLDCMTANQIVVLLVELARRNRIVVLT--IHQPRSelfqLFDKIAILSFGELI 272
Cdd:cd03260  157 ANEPEVLLLDEPTSALDPISTAKIEELIAELKKEYTIVIVThnMQQAAR----VADRTAFLLNGRLV 219
artP PRK11124
arginine transporter ATP-binding subunit; Provisional
67-251 5.84e-19

arginine transporter ATP-binding subunit; Provisional


Pssm-ID: 182980 [Multi-domain]  Cd Length: 242  Bit Score: 86.22  E-value: 5.84e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  67 QILKDVSLYVESGQIMCILGSSGSGKTTLLDAM-------SGRLGRAGT---FLGEVYVN-GRALRREqfqdcFSYVLQS 135
Cdd:PRK11124  16 QALFDITLDCPQGETLVLLGPSGAGKSSLLRVLnllemprSGTLNIAGNhfdFSKTPSDKaIRELRRN-----VGMVFQQ 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 136 DTLLSSLTVRETLhYTALLAIRRGNPGSFQKKVEAVMAELSLSHVADRlignYSLGgISTGERRRVSIAAQLLQDPKVML 215
Cdd:PRK11124  91 YNLWPHLTVQQNL-IEAPCRVLGLSKDQALARAEKLLERLRLKPYADR----FPLH-LSGGQQQRVAIARALMMEPQVLL 164
                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 530367936 216 FDEPTTGLDCMTANQIVVLLVELARRNRIVVLTIHQ 251
Cdd:PRK11124 165 FDEPTAALDPEITAQIVSIIRELAETGITQVIVTHE 200
PRK10851 PRK10851
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
66-279 6.33e-19

sulfate/thiosulfate ABC transporter ATP-binding protein CysA;


Pssm-ID: 182778 [Multi-domain]  Cd Length: 353  Bit Score: 88.22  E-value: 6.33e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  66 RQILKDVSLYVESGQIMCILGSSGSGKTTLLDAM-------SGRLGRAGTFLGEVYVNGRALrreqfqdcfSYVLQSDTL 138
Cdd:PRK10851  15 TQVLNDISLDIPSGQMVALLGPSGSGKTTLLRIIaglehqtSGHIRFHGTDVSRLHARDRKV---------GFVFQHYAL 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 139 LSSLTVRETLHY--TALLAIRRGNPGSFQKKVEAVMAELSLSHVADRLIGNyslggISTGERRRVSIAAQLLQDPKVMLF 216
Cdd:PRK10851  86 FRHMTVFDNIAFglTVLPRRERPNAAAIKAKVTQLLEMVQLAHLADRYPAQ-----LSGGQKQRVALARALAVEPQILLL 160
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 530367936 217 DEPTTGLDCMTANQIVVLLVELARRNRIVVLTIHQPRSELFQLFDKIAILSFGELIFCGTPAE 279
Cdd:PRK10851 161 DEPFGALDAQVRKELRRWLRQLHEELKFTSVFVTHDQEEAMEVADRVVVMSQGNIEQAGTPDQ 223
PRK11160 PRK11160
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
67-281 1.04e-18

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed


Pssm-ID: 236865 [Multi-domain]  Cd Length: 574  Bit Score: 89.50  E-value: 1.04e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  67 QILKDVSLYVESGQIMCILGSSGSGKTTLL-------DAMSGrlgragtflgEVYVNGRALRR---EQFQDCFSYVLQSD 136
Cdd:PRK11160 354 PVLKGLSLQIKAGEKVALLGRTGCGKSTLLqlltrawDPQQG----------EILLNGQPIADyseAALRQAISVVSQRV 423
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 137 TLLSSlTVRETLhytaLLAirrgNPGSFQKKVEAVMAELSLSHVADrliGNYSL------GG--ISTGERRRVSIAAQLL 208
Cdd:PRK11160 424 HLFSA-TLRDNL----LLA----APNASDEALIEVLQQVGLEKLLE---DDKGLnawlgeGGrqLSGGEQRRLGIARALL 491
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 530367936 209 QDPKVMLFDEPTTGLDCMTANQIVVLLVELArRNRIVVLTIHqpRSELFQLFDKIAILSFGELIFCGTPAEML 281
Cdd:PRK11160 492 HDAPLLLLDEPTEGLDAETERQILELLAEHA-QNKTVLMITH--RLTGLEQFDRICVMDNGQIIEQGTHQELL 561
ECF_ATPase_2 TIGR04521
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ...
66-279 1.10e-18

energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the downstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]


Pssm-ID: 275314 [Multi-domain]  Cd Length: 277  Bit Score: 86.35  E-value: 1.10e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936   66 RQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLgRAGTflGEVYVNG-----------RALRRE-----QF---Q 126
Cdd:TIGR04521  18 KKALDDVSLTIEDGEFVAIIGHTGSGKSTLIQHLNGLL-KPTS--GTVTIDGrditakkkkklKDLRKKvglvfQFpehQ 94
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  127 dcfsyvlqsdtlLSSLTVRETLHYtallairrGnPGSF-------QKKVEAVMAELSLSH-VADRlignySLGGISTGER 198
Cdd:TIGR04521  95 ------------LFEETVYKDIAF--------G-PKNLglseeeaEERVKEALELVGLDEeYLER-----SPFELSGGQM 148
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  199 RRVSIAAQLLQDPKVMLFDEPTTGLDCMTANQIVVLLVELAR-RNRIVVLTIHQpRSELFQLFDKIAILSFGELIFCGTP 277
Cdd:TIGR04521 149 RRVAIAGVLAMEPEVLILDEPTAGLDPKGRKEILDLFKRLHKeKGLTVILVTHS-MEDVAEYADRVIVMHKGKIVLDGTP 227

                  ..
gi 530367936  278 AE 279
Cdd:TIGR04521 228 RE 229
btuD PRK09536
corrinoid ABC transporter ATPase; Reviewed
68-281 1.14e-18

corrinoid ABC transporter ATPase; Reviewed


Pssm-ID: 236554 [Multi-domain]  Cd Length: 402  Bit Score: 88.36  E-value: 1.14e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  68 ILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGtflGEVYVNGRALR----REQFQDCFSyVLQSDTLLSSLT 143
Cdd:PRK09536  18 VLDGVDLSVREGSLVGLVGPNGAGKTTLLRAINGTLTPTA---GTVLVAGDDVEalsaRAASRRVAS-VPQDTSLSFEFD 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 144 VRETL------HYTallaiRRGNPGSFQKK-VEAVMAELSLSHVADRlignySLGGISTGERRRVSIAAQLLQDPKVMLF 216
Cdd:PRK09536  94 VRQVVemgrtpHRS-----RFDTWTETDRAaVERAMERTGVAQFADR-----PVTSLSGGERQRVLLARALAQATPVLLL 163
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 530367936 217 DEPTTGLDCMTANQIVVLLVELARRNRIVVLTIHQprSELFQLF-DKIAILSFGELIFCGTPAEML 281
Cdd:PRK09536 164 DEPTASLDINHQVRTLELVRRLVDDGKTAVAAIHD--LDLAARYcDELVLLADGRVRAAGPPADVL 227
metN PRK11153
DL-methionine transporter ATP-binding subunit; Provisional
62-272 1.65e-18

DL-methionine transporter ATP-binding subunit; Provisional


Pssm-ID: 236863 [Multi-domain]  Cd Length: 343  Bit Score: 86.78  E-value: 1.65e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  62 QQWTRQI--LKDVSLYVESGQIMCILGSSGSGKTTLLDAMSgRLGRAGTflGEVYVNGR--------ALRREQ------F 125
Cdd:PRK11153  12 PQGGRTIhaLNNVSLHIPAGEIFGVIGASGAGKSTLIRCIN-LLERPTS--GRVLVDGQdltalsekELRKARrqigmiF 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 126 QDcFSyvlqsdtLLSSLTVRETLhytAL-LAIRRGNPGSFQKKVEAVMAELSLSHVADRLIGNyslggISTGERRRVSIA 204
Cdd:PRK11153  89 QH-FN-------LLSSRTVFDNV---ALpLELAGTPKAEIKARVTELLELVGLSDKADRYPAQ-----LSGGQKQRVAIA 152
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 530367936 205 AQLLQDPKVMLFDEPTTGLDCMTANQIVVLLVELARRNRIVVLTI-HQpRSELFQLFDKIAILSFGELI 272
Cdd:PRK11153 153 RALASNPKVLLCDEATSALDPATTRSILELLKDINRELGLTIVLItHE-MDVVKRICDRVAVIDAGRLV 220
ThiQ COG3840
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
73-282 2.67e-18

ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];


Pssm-ID: 443051 [Multi-domain]  Cd Length: 232  Bit Score: 84.04  E-value: 2.67e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  73 SLYVESGQIMCILGSSGSGKTTLLDAMSGrlgragtFL----GEVYVNGRAL-RREQFQDCFSYVLQSDTLLSSLTVRET 147
Cdd:COG3840   19 DLTIAAGERVAILGPSGAGKSTLLNLIAG-------FLppdsGRILWNGQDLtALPPAERPVSMLFQENNLFPHLTVAQN 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 148 LhytaLLAIR-RGNPGSFQK-KVEAVMAELSLSHVADRLIGNyslggISTGERRRVSIAAQLLQDPKVMLFDEPTTGLDC 225
Cdd:COG3840   92 I----GLGLRpGLKLTAEQRaQVEQALERVGLAGLLDRLPGQ-----LSGGQRQRVALARCLVRKRPILLLDEPFSALDP 162
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 530367936 226 MTANQIVVLLVELARRNRIVVLTI-HQPRsELFQLFDKIAILSFGELIFCGTPAEMLD 282
Cdd:COG3840  163 ALRQEMLDLVDELCRERGLTVLMVtHDPE-DAARIADRVLLVADGRIAADGPTAALLD 219
ABCC_Protease_Secretion cd03246
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ...
68-271 3.04e-18

ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.


Pssm-ID: 213213 [Multi-domain]  Cd Length: 173  Bit Score: 82.26  E-value: 3.04e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  68 ILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGtflGEVYVNGRALR---REQFQDCFSYVLQSDTLLSsltv 144
Cdd:cd03246   17 VLRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLRPTS---GRVRLDGADISqwdPNELGDHVGYLPQDDELFS---- 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 145 retlhytallairrgnpGSfqkkveavmaelslshVADRLignyslggISTGERRRVSIAAQLLQDPKVMLFDEPTTGLD 224
Cdd:cd03246   90 -----------------GS----------------IAENI--------LSGGQRQRLGLARALYGNPRILVLDEPNSHLD 128
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 530367936 225 CMTANQIVVLLVELARRNRIVVLTIHQPrsELFQLFDKIAILSFGEL 271
Cdd:cd03246  129 VEGERALNQAIAALKAAGATRIVIAHRP--ETLASADRILVLEDGRV 173
ABC_Carb_Monos_II cd03215
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ...
69-271 3.66e-18

Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213182 [Multi-domain]  Cd Length: 182  Bit Score: 82.48  E-value: 3.66e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  69 LKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGtflGEVYVNGRALRReqfqdcfsyvlqsdtllssLTVREtl 148
Cdd:cd03215   16 VRDVSFEVRAGEIVGIAGLVGNGQTELAEALFGLRPPAS---GEITLDGKPVTR-------------------RSPRD-- 71
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 149 hytallAIRRGN---PGSfqKKVEAVMAELSlshVADRLIGNYSLGGistGERRRVSIAAQLLQDPKVMLFDEPTTGLDC 225
Cdd:cd03215   72 ------AIRAGIayvPED--RKREGLVLDLS---VAENIALSSLLSG---GNQQKVVLARWLARDPRVLILDEPTRGVDV 137
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 530367936 226 MTANQIVVLLVELARRNR-IVVLTIHQPrsELFQLFDKIAILSFGEL 271
Cdd:cd03215  138 GAKAEIYRLIRELADAGKaVLLISSELD--ELLGLCDRILVMYEGRI 182
cbiO PRK13632
cobalt transporter ATP-binding subunit; Provisional
65-281 4.49e-18

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237452 [Multi-domain]  Cd Length: 271  Bit Score: 84.27  E-value: 4.49e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  65 TRQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGtflGEVYVNGRALRRE---QFQDCFSYVLQS-DTLLS 140
Cdd:PRK13632  21 ENNALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLLKPQS---GEIKIDGITISKEnlkEIRKKIGIIFQNpDNQFI 97
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 141 SLTVRETLHYTalLAIRRGNPGSFQKKVEAVMAELSLSHVADRLIGNyslggISTGERRRVSIAAQLLQDPKVMLFDEPT 220
Cdd:PRK13632  98 GATVEDDIAFG--LENKKVPPKKMKDIIDDLAKKVGMEDYLDKEPQN-----LSGGQKQRVAIASVLALNPEIIIFDEST 170
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 530367936 221 TGLDCMTANQIVVLLVELARRNRIVVLTIHQPRSELFqLFDKIAILSFGELIFCGTPAEML 281
Cdd:PRK13632 171 SMLDPKGKREIKKIMVDLRKTRKKTLISITHDMDEAI-LADKVIVFSEGKLIAQGKPKEIL 230
CydC TIGR02868
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ...
68-252 4.55e-18

thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.


Pssm-ID: 274331 [Multi-domain]  Cd Length: 530  Bit Score: 87.42  E-value: 4.55e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936   68 ILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGtflGEVYVNG---RALRREQFQDCFSYVLQSDTLLSSlTV 144
Cdd:TIGR02868 350 VLDGVSLDLPPGERVAILGPSGSGKSTLLATLAGLLDPLQ---GEVTLDGvpvSSLDQDEVRRRVSVCAQDAHLFDT-TV 425
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  145 RETLhytallaiRRGNPGSFQKKVEAVMAELSLSHVADRLIGNYS--LGG----ISTGERRRVSIAAQLLQDPKVMLFDE 218
Cdd:TIGR02868 426 RENL--------RLARPDATDEELWAALERVGLADWLRALPDGLDtvLGEggarLSGGERQRLALARALLADAPILLLDE 497
                         170       180       190
                  ....*....|....*....|....*....|....
gi 530367936  219 PTTGLDCMTANQIVVLLVElARRNRIVVLTIHQP 252
Cdd:TIGR02868 498 PTEHLDAETADELLEDLLA-ALSGRTVVLITHHL 530
ABCC_cytochrome_bd cd03247
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ...
67-275 4.89e-18

ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.


Pssm-ID: 213214 [Multi-domain]  Cd Length: 178  Bit Score: 81.98  E-value: 4.89e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  67 QILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAgtfLGEVYVNGR--ALRREQFQDCFSYVLQSDTLLSSlTV 144
Cdd:cd03247   16 QVLKNLSLELKQGEKIALLGRSGSGKSTLLQLLTGDLKPQ---QGEITLDGVpvSDLEKALSSLISVLNQRPYLFDT-TL 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 145 RETLHytallaiRRgnpgsfqkkveavmaelslshvadrlignyslggISTGERRRVSIAAQLLQDPKVMLFDEPTTGLD 224
Cdd:cd03247   92 RNNLG-------RR----------------------------------FSGGERQRLALARILLQDAPIVLLDEPTVGLD 130
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 530367936 225 CMTANQIVVLLVELArRNRIVVLTIHQPRSelFQLFDKIAILSFGELIFCG 275
Cdd:cd03247  131 PITERQLLSLIFEVL-KDKTLIWITHHLTG--IEHMDKILFLENGKIIMQG 178
DppD COG0444
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ...
71-241 6.24e-18

ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440213 [Multi-domain]  Cd Length: 320  Bit Score: 84.72  E-value: 6.24e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  71 DVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGTFLGEVYVNGR---ALRREQFQD----CFSYVLQSDtlLSSL- 142
Cdd:COG0444   23 GVSFDVRRGETLGLVGESGSGKSTLARAILGLLPPPGITSGEILFDGEdllKLSEKELRKirgrEIQMIFQDP--MTSLn 100
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 143 ---TVRETLHYtALLAIRRGNPGSFQKKVEAVMAELSLSHVADRLiGNY--SLGGistGERRRVSIAAQLLQDPKVMLFD 217
Cdd:COG0444  101 pvmTVGDQIAE-PLRIHGGLSKAEARERAIELLERVGLPDPERRL-DRYphELSG---GMRQRVMIARALALEPKLLIAD 175
                        170       180
                 ....*....|....*....|....
gi 530367936 218 EPTTGLDCMTANQIVVLLVELARR 241
Cdd:COG0444  176 EPTTALDVTIQAQILNLLKDLQRE 199
PRK14246 PRK14246
phosphate ABC transporter ATP-binding protein; Provisional
66-281 2.72e-17

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172734 [Multi-domain]  Cd Length: 257  Bit Score: 82.02  E-value: 2.72e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  66 RQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSgRL-----------GRAGTFLGEVY-VNGRALRREqfqdcFSYVL 133
Cdd:PRK14246  23 KAILKDITIKIPNNSIFGIMGPSGSGKSTLLKVLN-RLieiydskikvdGKVLYFGKDIFqIDAIKLRKE-----VGMVF 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 134 QSDTLLSSLTVRETLHYtALLAIRRGNPGSFQKKVEAVMAELSL-SHVADRLigNYSLGGISTGERRRVSIAAQLLQDPK 212
Cdd:PRK14246  97 QQPNPFPHLSIYDNIAY-PLKSHGIKEKREIKKIVEECLRKVGLwKEVYDRL--NSPASQLSGGQQQRLTIARALALKPK 173
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 530367936 213 VMLFDEPTTGLDCMTANQIVVLLVELARRNRIVVLTiHQPRsELFQLFDKIAILSFGELIFCGTPAEML 281
Cdd:PRK14246 174 VLLMDEPTSMIDIVNSQAIEKLITELKNEIAIVIVS-HNPQ-QVARVADYVAFLYNGELVEWGSSNEIF 240
hmuV PRK13547
heme ABC transporter ATP-binding protein;
66-281 2.86e-17

heme ABC transporter ATP-binding protein;


Pssm-ID: 184132 [Multi-domain]  Cd Length: 272  Bit Score: 82.18  E-value: 2.86e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  66 RQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRL-----GRAGTFLGEVYVNGRALRREQFQD--CFSYVL-QSDT 137
Cdd:PRK13547  14 RAILRDLSLRIEPGRVTALLGRNGAGKSTLLKALAGDLtgggaPRGARVTGDVTLNGEPLAAIDAPRlaRLRAVLpQAAQ 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 138 LLSSLTVRETLHYTALLAIRRGNPGSFQKKvEAVMAELSLSHvADRLIGNySLGGISTGERRRVSIA---AQL------L 208
Cdd:PRK13547  94 PAFAFSAREIVLLGRYPHARRAGALTHRDG-EIAWQALALAG-ATALVGR-DVTTLSGGELARVQFArvlAQLwpphdaA 170
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 530367936 209 QDPKVMLFDEPTTGLDCMTANQIVVLLVELARRNRIVVLTI-HQPRSELfQLFDKIAILSFGELIFCGTPAEML 281
Cdd:PRK13547 171 QPPRYLLLDEPTAALDLAHQHRLLDTVRRLARDWNLGVLAIvHDPNLAA-RHADRIAMLADGAIVAHGAPADVL 243
PRK10535 PRK10535
macrolide ABC transporter ATP-binding protein/permease MacB;
67-252 3.36e-17

macrolide ABC transporter ATP-binding protein/permease MacB;


Pssm-ID: 182528 [Multi-domain]  Cd Length: 648  Bit Score: 85.16  E-value: 3.36e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  67 QILKDVSLYVESGQIMCILGSSGSGKTTLLDAMsGRLGRAGTflGEVYVNGR-----------ALRREQFqdcfSYVLQS 135
Cdd:PRK10535  22 EVLKGISLDIYAGEMVAIVGASGSGKSTLMNIL-GCLDKPTS--GTYRVAGQdvatldadalaQLRREHF----GFIFQR 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 136 DTLLSSLTVRETLHYTALLAirrGNP-GSFQKKVEAVMAELSLshvADRLigNYSLGGISTGERRRVSIAAQLLQDPKVM 214
Cdd:PRK10535  95 YHLLSHLTAAQNVEVPAVYA---GLErKQRLLRAQELLQRLGL---EDRV--EYQPSQLSGGQQQRVSIARALMNGGQVI 166
                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 530367936 215 LFDEPTTGLDCMTANQIVVLLVELARRNRIVVLTIHQP 252
Cdd:PRK10535 167 LADEPTGALDSHSGEEVMAILHQLRDRGHTVIIVTHDP 204
ABC_ThiQ_thiamine_transporter cd03298
ATP-binding cassette domain of the thiamine transport system; Part of the ...
71-275 4.22e-17

ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213265 [Multi-domain]  Cd Length: 211  Bit Score: 80.23  E-value: 4.22e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  71 DVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGtflGEVYVNGRALRREQFQD-CFSYVLQSDTLLSSLTVRETLH 149
Cdd:cd03298   16 HFDLTFAQGEITAIVGPSGSGKSTLLNLIAGFETPQS---GRVLINGVDVTAAPPADrPVSMLFQENNLFAHLTVEQNVG 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 150 ytalLAIrrgNPG-----SFQKKVEAVMAELSLSHVADRLIGNyslggISTGERRRVSIAAQLLQDPKVMLFDEPTTGLD 224
Cdd:cd03298   93 ----LGL---SPGlkltaEDRQAIEVALARVGLAGLEKRLPGE-----LSGGERQRVALARVLVRDKPVLLLDEPFAALD 160
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 530367936 225 CMTANQIVVLLVELARRNRIVVLTI-HQPrSELFQLFDKIAILSFGELIFCG 275
Cdd:cd03298  161 PALRAEMLDLVLDLHAETKMTVLMVtHQP-EDAKRLAQRVVFLDNGRIAAQG 211
AbcC COG1135
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
69-294 4.28e-17

ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 440750 [Multi-domain]  Cd Length: 339  Bit Score: 82.82  E-value: 4.28e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  69 LKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGrLGRAGTflGEVYVNG-----------RALRREqfqdcFSYVLQSDT 137
Cdd:COG1135   21 LDDVSLTIEKGEIFGIIGYSGAGKSTLIRCINL-LERPTS--GSVLVDGvdltalserelRAARRK-----IGMIFQHFN 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 138 LLSSLTVRETLhytAL-LAIRRGNPGSFQKKVEAVMAELSLSHVADRLIGNyslggISTGERRRVSIAAQLLQDPKVMLF 216
Cdd:COG1135   93 LLSSRTVAENV---ALpLEIAGVPKAEIRKRVAELLELVGLSDKADAYPSQ-----LSGGQKQRVGIARALANNPKVLLC 164
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 217 DEPTTGLDCMTANQIVVLLVELARRNRI-VVLTIHQP---RselfQLFDKIAILSFGELIFCGTpaeMLDFFNDcgypcP 292
Cdd:COG1135  165 DEATSALDPETTRSILDLLKDINRELGLtIVLITHEMdvvR----RICDRVAVLENGRIVEQGP---VLDVFAN-----P 232

                 ..
gi 530367936 293 EH 294
Cdd:COG1135  233 QS 234
PRK10575 PRK10575
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
66-281 4.40e-17

Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;


Pssm-ID: 182561 [Multi-domain]  Cd Length: 265  Bit Score: 81.37  E-value: 4.40e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  66 RQILKDVSLYVESGQIMCILGSSGSGKTTLLDaMSGRLGRAGTflGEVYVNGRAL---RREQFQDCFSYVLQSDTLLSSL 142
Cdd:PRK10575  24 RTLLHPLSLTFPAGKVTGLIGHNGSGKSTLLK-MLGRHQPPSE--GEILLDAQPLeswSSKAFARKVAYLPQQLPAAEGM 100
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 143 TVREtlhytaLLAIRR----GNPGSF----QKKVEAVMAELSLSHVADRLIGnySLGGistGERRRVSIAAQLLQDPKVM 214
Cdd:PRK10575 101 TVRE------LVAIGRypwhGALGRFgaadREKVEEAISLVGLKPLAHRLVD--SLSG---GERQRAWIAMLVAQDSRCL 169
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 530367936 215 LFDEPTTGLDcmTANQIVVL-LVE-LARRNRIVVLTIHQPRSELFQLFDKIAILSFGELIFCGTPAEML 281
Cdd:PRK10575 170 LLDEPTSALD--IAHQVDVLaLVHrLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGTPAELM 236
PRK13538 PRK13538
cytochrome c biogenesis heme-transporting ATPase CcmA;
66-252 6.22e-17

cytochrome c biogenesis heme-transporting ATPase CcmA;


Pssm-ID: 184125 [Multi-domain]  Cd Length: 204  Bit Score: 79.46  E-value: 6.22e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  66 RQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGrLGRAGTflGEVYVNGRALR--REQFQDCFSYVLQSDTLLSSLT 143
Cdd:PRK13538  14 RILFSGLSFTLNAGELVQIEGPNGAGKTSLLRILAG-LARPDA--GEVLWQGEPIRrqRDEYHQDLLYLGHQPGIKTELT 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 144 VRETLHYTALLAirrGNPGSFQkkVEAVMAELSLSHVADRLIGNyslggISTGERRRVSIAAQLLQDPKVMLFDEPTTGL 223
Cdd:PRK13538  91 ALENLRFYQRLH---GPGDDEA--LWEALAQVGLAGFEDVPVRQ-----LSAGQQRRVALARLWLTRAPLWILDEPFTAI 160
                        170       180
                 ....*....|....*....|....*....
gi 530367936 224 DCMTANQIVVLLVELARRNRIVVLTIHQP 252
Cdd:PRK13538 161 DKQGVARLEALLAQHAEQGGMVILTTHQD 189
PRK10584 PRK10584
putative ABC transporter ATP-binding protein YbbA; Provisional
68-253 6.78e-17

putative ABC transporter ATP-binding protein YbbA; Provisional


Pssm-ID: 182569 [Multi-domain]  Cd Length: 228  Bit Score: 79.82  E-value: 6.78e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  68 ILKDVSLYVESGQIMCILGSSGSGKTTLL-------DAMSGRLGRAGTFLGEVYVNGRALRREQFqdcFSYVLQSDTLLS 140
Cdd:PRK10584  25 ILTGVELVVKRGETIALIGESGSGKSTLLailagldDGSSGEVSLVGQPLHQMDEEARAKLRAKH---VGFVFQSFMLIP 101
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 141 SLTVRETLHYTALLaiRRGNPGSFQKKVEAVMAELSLSHVADRLIGNyslggISTGERRRVSIAAQLLQDPKVMLFDEPT 220
Cdd:PRK10584 102 TLNALENVELPALL--RGESSRQSRNGAKALLEQLGLGKRLDHLPAQ-----LSGGEQQRVALARAFNGRPDVLFADEPT 174
                        170       180       190
                 ....*....|....*....|....*....|....
gi 530367936 221 TGLDCMTANQIVVLLVELARR-NRIVVLTIHQPR 253
Cdd:PRK10584 175 GNLDRQTGDKIADLLFSLNREhGTTLILVTHDLQ 208
PRK15056 PRK15056
manganese/iron ABC transporter ATP-binding protein;
69-250 2.21e-16

manganese/iron ABC transporter ATP-binding protein;


Pssm-ID: 185016 [Multi-domain]  Cd Length: 272  Bit Score: 79.54  E-value: 2.21e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  69 LKDVSLYVESGQIMCILGSSGSGKTTLLDAMSG--RLGRagtflGEVYVNGRALRREQFQDCFSYVLQSDTLLSSLTVre 146
Cdd:PRK15056  23 LRDASFTVPGGSIAALVGVNGSGKSTLFKALMGfvRLAS-----GKISILGQPTRQALQKNLVAYVPQSEEVDWSFPV-- 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 147 tLHYTALLAIRRGNPGSF-------QKKVEAVMAELSLSHVADRLIGNyslggISTGERRRVSIAAQLLQDPKVMLFDEP 219
Cdd:PRK15056  96 -LVEDVVMMGRYGHMGWLrrakkrdRQIVTAALARVDMVEFRHRQIGE-----LSGGQKKRVFLARAIAQQGQVILLDEP 169
                        170       180       190
                 ....*....|....*....|....*....|.
gi 530367936 220 TTGLDCMTANQIVVLLVELARRNRIVVLTIH 250
Cdd:PRK15056 170 FTGVDVKTEARIISLLRELRDEGKTMLVSTH 200
PRK09984 PRK09984
phosphonate ABC transporter ATP-binding protein;
67-276 2.29e-16

phosphonate ABC transporter ATP-binding protein;


Pssm-ID: 182182 [Multi-domain]  Cd Length: 262  Bit Score: 79.29  E-value: 2.29e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  67 QILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGTFLGEVYVNGRALRRE--------QFQDCFSYVLQSDTL 138
Cdd:PRK09984  18 QALHAVDLNIHHGEMVALLGPSGSGKSTLLRHLSGLITGDKSAGSHIELLGRTVQREgrlardirKSRANTGYIFQQFNL 97
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 139 LSSLTVRETLHYTAL-------LAIRRGNPGSFQKKVEAvMAELSLSHVADRLIGNyslggISTGERRRVSIAAQLLQDP 211
Cdd:PRK09984  98 VNRLSVLENVLIGALgstpfwrTCFSWFTREQKQRALQA-LTRVGMVHFAHQRVST-----LSGGQQQRVAIARALMQQA 171
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 530367936 212 KVMLFDEPTTGLDCMTANQIVVLLVELARRNRI-VVLTIHQPRSELfQLFDKIAILSFGELIFCGT 276
Cdd:PRK09984 172 KVILADEPIASLDPESARIVMDTLRDINQNDGItVVVTLHQVDYAL-RYCERIVALRQGHVFYDGS 236
PRK10619 PRK10619
histidine ABC transporter ATP-binding protein HisP;
67-251 2.44e-16

histidine ABC transporter ATP-binding protein HisP;


Pssm-ID: 182592 [Multi-domain]  Cd Length: 257  Bit Score: 78.86  E-value: 2.44e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  67 QILKDVSLYVESGQIMCILGSSGSGKTTLLdamsgrlgRAGTFL-----GEVYVNGRALR-------------REQFQDC 128
Cdd:PRK10619  19 EVLKGVSLQANAGDVISIIGSSGSGKSTFL--------RCINFLekpseGSIVVNGQTINlvrdkdgqlkvadKNQLRLL 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 129 ---FSYVLQSDTLLSSLTVRETLHYTALLAIrrgnpgSFQKKVEAVMAELSLSHVA--DRLIGNYSLGgISTGERRRVSI 203
Cdd:PRK10619  91 rtrLTMVFQHFNLWSHMTVLENVMEAPIQVL------GLSKQEARERAVKYLAKVGidERAQGKYPVH-LSGGQQQRVSI 163
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 530367936 204 AAQLLQDPKVMLFDEPTTGLDCMTANQIVVLLVELARRNRIVVLTIHQ 251
Cdd:PRK10619 164 ARALAMEPEVLLFDEPTSALDPELVGEVLRIMQQLAEEGKTMVVVTHE 211
ABCC_bacteriocin_exporters cd03245
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ...
69-272 2.63e-16

ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.


Pssm-ID: 213212 [Multi-domain]  Cd Length: 220  Bit Score: 78.02  E-value: 2.63e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  69 LKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGrLGRAGTflGEVYVNG--------RALRREqfqdcFSYVLQSDTLLS 140
Cdd:cd03245   20 LDNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAG-LYKPTS--GSVLLDGtdirqldpADLRRN-----IGYVPQDVTLFY 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 141 SlTVRETLHYTALLAirrgnpgsfqkKVEAVMAELSLSHVADrLIGNYSLG----------GISTGERRRVSIAAQLLQD 210
Cdd:cd03245   92 G-TLRDNITLGAPLA-----------DDERILRAAELAGVTD-FVNKHPNGldlqigergrGLSGGQRQAVALARALLND 158
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 530367936 211 PKVMLFDEPTTGLDCMTANQIVVLLVELARRNRIVVLTiHqpRSELFQLFDKIAILSFGELI 272
Cdd:cd03245  159 PPILLLDEPTSAMDMNSEERLKERLRQLLGDKTLIIIT-H--RPSLLDLVDRIIVMDSGRIV 217
ABC_Carb_Monos_I cd03216
First domain of the ATP-binding cassette component of monosaccharide transport system; This ...
67-272 2.68e-16

First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.


Pssm-ID: 213183 [Multi-domain]  Cd Length: 163  Bit Score: 76.31  E-value: 2.68e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  67 QILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGtflGEVYVNGRALrreqfqdcfsyvlqsdtllSSLTVRE 146
Cdd:cd03216   14 KALDGVSLSVRRGEVHALLGENGAGKSTLMKILSGLYKPDS---GEILVDGKEV-------------------SFASPRD 71
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 147 tlhytallAIRRGnpgsfqkkVEAVmaelslshvadrlignYSLggiSTGERRRVSIAAQLLQDPKVMLFDEPTTGLDCM 226
Cdd:cd03216   72 --------ARRAG--------IAMV----------------YQL---SVGERQMVEIARALARNARLLILDEPTAALTPA 116
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 530367936 227 TANQIVVLLVELARRNRIVVLTIHQPRsELFQLFDKIAILSFGELI 272
Cdd:cd03216  117 EVERLFKVIRRLRAQGVAVIFISHRLD-EVFEIADRVTVLRDGRVV 161
COG4586 COG4586
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ...
69-250 2.75e-16

ABC-type uncharacterized transport system, ATPase component [General function prediction only];


Pssm-ID: 443643 [Multi-domain]  Cd Length: 323  Bit Score: 80.13  E-value: 2.75e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  69 LKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGtflGEVYVNGR--ALRREQFQDCFSYVL-QSDTLLSSLTVR 145
Cdd:COG4586   38 VDDISFTIEPGEIVGFIGPNGAGKSTTIKMLTGILVPTS---GEVRVLGYvpFKRRKEFARRIGVVFgQRSQLWWDLPAI 114
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 146 ETLHYTAllAIRRGNPGSFQKKVEAVMAELSLSHVADRLIGNYSLGgistgERRRVSIAAQLLQDPKVMLFDEPTTGLDC 225
Cdd:COG4586  115 DSFRLLK--AIYRIPDAEYKKRLDELVELLDLGELLDTPVRQLSLG-----QRMRCELAAALLHRPKILFLDEPTIGLDV 187
                        170       180
                 ....*....|....*....|....*.
gi 530367936 226 MTANQIVVLLVEL-ARRNRIVVLTIH 250
Cdd:COG4586  188 VSKEAIREFLKEYnRERGTTILLTSH 213
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
80-287 3.14e-16

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 82.75  E-value: 3.14e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936    80 QIMCILGSSGSGKTTLLDAMSGRLGRAGtflGEVYVNGRALRR--EQFQDCFSYVLQSDTLLSSLTVRETLHYTALLAIR 157
Cdd:TIGR01257  957 QITAFLGHNGAGKTTTLSILTGLLPPTS---GTVLVGGKDIETnlDAVRQSLGMCPQHNILFHHLTVAEHILFYAQLKGR 1033
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936   158 RGNPGsfQKKVEAVMAELSLSHVAdrligNYSLGGISTGERRRVSIAAQLLQDPKVMLFDEPTTGLDCMTANQIVVLLVE 237
Cdd:TIGR01257 1034 SWEEA--QLEMEAMLEDTGLHHKR-----NEEAQDLSGGMQRKLSVAIAFVGDAKVVVLDEPTSGVDPYSRRSIWDLLLK 1106
                          170       180       190       200       210
                   ....*....|....*....|....*....|....*....|....*....|
gi 530367936   238 LARRNRIVVLTIHQPRSELfqLFDKIAILSFGELIFCGTPAemldFFNDC 287
Cdd:TIGR01257 1107 YRSGRTIIMSTHHMDEADL--LGDRIAIISQGRLYCSGTPL----FLKNC 1150
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
67-284 4.60e-16

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 81.00  E-value: 4.60e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936   67 QILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSG-------------------------RLGRAGT------------- 108
Cdd:TIGR03269  14 EVLKNISFTIEEGEVLGILGRSGAGKSVLMHVLRGmdqyeptsgriiyhvalcekcgyveRPSKVGEpcpvcggtlepee 93
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  109 --FLGEVYVNGRALRRE---QFQDCFSYVLQSDTLLSSLTVRETLHYTALLAIRRGnpgsfQKKVEAVMAELSLSHVADR 183
Cdd:TIGR03269  94 vdFWNLSDKLRRRIRKRiaiMLQRTFALYGDDTVLDNVLEALEEIGYEGKEAVGRA-----VDLIEMVQLSHRITHIARD 168
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  184 LIGnyslggistGERRRVSIAAQLLQDPKVMLFDEPTTGLDCMTANQIVVLLVELARRNRI-VVLTIHQPRSeLFQLFDK 262
Cdd:TIGR03269 169 LSG---------GEKQRVVLARQLAKEPFLFLADEPTGTLDPQTAKLVHNALEEAVKASGIsMVLTSHWPEV-IEDLSDK 238
                         250       260
                  ....*....|....*....|..
gi 530367936  263 IAILSFGELIFCGTPAEMLDFF 284
Cdd:TIGR03269 239 AIWLENGEIKEEGTPDEVVAVF 260
PRK10070 PRK10070
proline/glycine betaine ABC transporter ATP-binding protein ProV;
69-282 5.27e-16

proline/glycine betaine ABC transporter ATP-binding protein ProV;


Pssm-ID: 182221 [Multi-domain]  Cd Length: 400  Bit Score: 80.08  E-value: 5.27e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  69 LKDVSLYVESGQIMCILGSSGSGKTTLLDAMSgRLGRAGTflGEVYVNG-----------RALRREQFqdcfSYVLQSDT 137
Cdd:PRK10070  44 VKDASLAIEEGEIFVIMGLSGSGKSTMVRLLN-RLIEPTR--GQVLIDGvdiakisdaelREVRRKKI----AMVFQSFA 116
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 138 LLSSLTVRETLHYTALLAirrGNPGSFQKkveavmaELSLSHVADRLIGNYSLG---GISTGERRRVSIAAQLLQDPKVM 214
Cdd:PRK10070 117 LMPHMTVLDNTAFGMELA---GINAEERR-------EKALDALRQVGLENYAHSypdELSGGMRQRVGLARALAINPDIL 186
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 530367936 215 LFDEPTTGLDCMTANQIVVLLVELARRNRIVVLTIHQPRSELFQLFDKIAILSFGELIFCGTPAEMLD 282
Cdd:PRK10070 187 LMDEAFSALDPLIRTEMQDELVKLQAKHQRTIVFISHDLDEAMRIGDRIAIMQNGEVVQVGTPDEILN 254
cbiO PRK13631
cobalt transporter ATP-binding subunit; Provisional
68-285 5.83e-16

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237451 [Multi-domain]  Cd Length: 320  Bit Score: 79.12  E-value: 5.83e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  68 ILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRL-GRAGTF-LGEVYVNGRALRREQFQDCFSYVLQSDTLLSSLT-- 143
Cdd:PRK13631  41 ALNNISYTFEKNKIYFIIGNSGSGKSTLVTHFNGLIkSKYGTIqVGDIYIGDKKNNHELITNPYSKKIKNFKELRRRVsm 120
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 144 VRETLHY-----TALLAIRRGNPGSFQKKVEAvmAELSLSHVADRLIGNYSLG----GISTGERRRVSIAAQLLQDPKVM 214
Cdd:PRK13631 121 VFQFPEYqlfkdTIEKDIMFGPVALGVKKSEA--KKLAKFYLNKMGLDDSYLErspfGLSGGQKRRVAIAGILAIQPEIL 198
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 530367936 215 LFDEPTTGLDCMTANQIVVLLVELARRNRIVVLTIHQpRSELFQLFDKIAILSFGELIFCGTPAEMldFFN 285
Cdd:PRK13631 199 IFDEPTAGLDPKGEHEMMQLILDAKANNKTVFVITHT-MEHVLEVADEVIVMDKGKILKTGTPYEI--FTD 266
rim_protein TIGR01257
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ...
76-289 6.01e-16

retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]


Pssm-ID: 130324 [Multi-domain]  Cd Length: 2272  Bit Score: 81.60  E-value: 6.01e-16
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936    76 VESGQIMCILGSSGSGKTTLLDAMSGRLGRAGtflGEVYVNGRALRR--EQFQDCFSYVLQSDTLLSSLTVRETLHYTAL 153
Cdd:TIGR01257 1962 VRPGECFGLLGVNGAGKTTTFKMLTGDTTVTS---GDATVAGKSILTniSDVHQNMGYCPQFDAIDDLLTGREHLYLYAR 2038
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936   154 LairRGNPGsfqKKVEAV----MAELSLSHVADRLIGNYSlggisTGERRRVSIAAQLLQDPKVMLFDEPTTGLDCMTAN 229
Cdd:TIGR01257 2039 L---RGVPA---EEIEKVanwsIQSLGLSLYADRLAGTYS-----GGNKRKLSTAIALIGCPPLVLLDEPTTGMDPQARR 2107
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936   230 QIVVLLVELARRNRIVVLTIHQpRSELFQLFDKIAILSFGELIFCGTPAEMLDFFNDcGY 289
Cdd:TIGR01257 2108 MLWNTIVSIIREGRAVVLTSHS-MEECEALCTRLAIMVKGAFQCLGTIQHLKSKFGD-GY 2165
PRK03695 PRK03695
vitamin B12-transporter ATPase; Provisional
72-281 6.96e-16

vitamin B12-transporter ATPase; Provisional


Pssm-ID: 235150 [Multi-domain]  Cd Length: 248  Bit Score: 77.28  E-value: 6.96e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  72 VSLYVESGQIMCILGSSGSGKTTLLDAMSGRLgragTFLGEVYVNGRAL----------RReqfqdcfSYVLQSDTLLSS 141
Cdd:PRK03695  15 LSAEVRAGEILHLVGPNGAGKSTLLARMAGLL----PGSGSIQFAGQPLeawsaaelarHR-------AYLSQQQTPPFA 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 142 LTVretLHYTALLAIRRGNPGSFQKKVEAVMAELSLshvADRLigNYSLGGISTGERRRVSIAAQLLQ-------DPKVM 214
Cdd:PRK03695  84 MPV---FQYLTLHQPDKTRTEAVASALNEVAEALGL---DDKL--GRSVNQLSGGEWQRVRLAAVVLQvwpdinpAGQLL 155
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 530367936 215 LFDEPTTGLDCMTANQIVVLLVELARRNRIVVLTIHQPRSELFQLfDKIAILSFGELIFCGTPAEML 281
Cdd:PRK03695 156 LLDEPMNSLDVAQQAALDRLLSELCQQGIAVVMSSHDLNHTLRHA-DRVWLLKQGKLLASGRRDEVL 221
ABC2_membrane pfam01061
ABC-2 type transporter;
371-549 7.27e-16

ABC-2 type transporter;


Pssm-ID: 426023 [Multi-domain]  Cd Length: 204  Bit Score: 76.54  E-value: 7.27e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  371 LLRRVTRNLVRNKLAVITRLLQNLIMGLFL--LFFVLRvrsnvLKGAIQDRVGLLYQFVGATPYTGMLNAVNLFPVLRAV 448
Cdd:pfam01061   1 LLKREFLRRWRDPSLGLWRLIQPILMALIFgtLFGNLG-----NQQGGLNRPGLLFFSILFNAFSALSGISPVFEKERGV 75
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  449 SDQESQDGLYQKWQMMLAYALHVLPFSVVATMIFSSVCYWTLGLHPEVARFGYFSAALLAPHLIGEFLTLVLLGIVQNPN 528
Cdd:pfam01061  76 LYRELASPLYSPSAYVLAKILSELPLSLLQSLIFLLIVYFMVGLPPSAGRFFLFLLVLLLTALAASSLGLFISALAPSFE 155
                         170       180
                  ....*....|....*....|.
gi 530367936  529 IVNSVVALLSIAGVLVgSGFL 549
Cdd:pfam01061 156 DASQLGPLVLLPLLLL-SGFF 175
tauB PRK11248
taurine ABC transporter ATP-binding subunit;
66-249 8.90e-16

taurine ABC transporter ATP-binding subunit;


Pssm-ID: 183056 [Multi-domain]  Cd Length: 255  Bit Score: 77.43  E-value: 8.90e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  66 RQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLG-RAGTF-LGEVYVNGRALRReqfqdcfSYVLQSDTLLSSLT 143
Cdd:PRK11248  14 KPALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPyQHGSItLDGKPVEGPGAER-------GVVFQNEGLLPWRN 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 144 VRETLHYTALLAirrGNPGSFQKKVEAVM-AELSLSHVADRLIgnYSLGGistGERRRVSIAAQLLQDPKVMLFDEPTTG 222
Cdd:PRK11248  87 VQDNVAFGLQLA---GVEKMQRLEIAHQMlKKVGLEGAEKRYI--WQLSG---GQRQRVGIARALAANPQLLLLDEPFGA 158
                        170       180
                 ....*....|....*....|....*..
gi 530367936 223 LDCMTANQIVVLLVELARRNRIVVLTI 249
Cdd:PRK11248 159 LDAFTREQMQTLLLKLWQETGKQVLLI 185
SufC COG0396
Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, ...
66-253 9.51e-16

Fe-S cluster assembly ATPase SufC [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440165 [Multi-domain]  Cd Length: 245  Bit Score: 77.03  E-value: 9.51e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  66 RQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGTfLGEVYVNG----------RAlRREQFqdcfsYVLQS 135
Cdd:COG0396   13 KEILKGVNLTIKPGEVHAIMGPNGSGKSTLAKVLMGHPKYEVT-SGSILLDGedilelspdeRA-RAGIF-----LAFQY 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 136 DTLLSSLTVRETLHyTALLAIRRGNPGS--FQKKVEAVMAELSLSH-VADRlignySL-GGISTGERRRVSIAAQLLQDP 211
Cdd:COG0396   86 PVEIPGVSVSNFLR-TALNARRGEELSAreFLKLLKEKMKELGLDEdFLDR-----YVnEGFSGGEKKRNEILQMLLLEP 159
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 530367936 212 KVMLFDEPTTGLDcMTANQIVVLLV-ELARRNRIVVLTIHQPR 253
Cdd:COG0396  160 KLAILDETDSGLD-IDALRIVAEGVnKLRSPDRGILIITHYQR 201
PRK11000 PRK11000
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
68-280 1.02e-15

maltose/maltodextrin ABC transporter ATP-binding protein MalK;


Pssm-ID: 182893 [Multi-domain]  Cd Length: 369  Bit Score: 78.92  E-value: 1.02e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  68 ILKDVSLYVESGQIMCILGSSGSGKTTLL-------DAMSGRLgragtFLGEVYVN-----GRALrreqfqdcfSYVLQS 135
Cdd:PRK11000  18 ISKDINLDIHEGEFVVFVGPSGCGKSTLLrmiagleDITSGDL-----FIGEKRMNdvppaERGV---------GMVFQS 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 136 DTLLSSLTVRETLHYTALLAirRGNPGSFQKKVEAVMAELSLSHVADRlignySLGGISTGERRRVSIAAQLLQDPKVML 215
Cdd:PRK11000  84 YALYPHLSVAENMSFGLKLA--GAKKEEINQRVNQVAEVLQLAHLLDR-----KPKALSGGQRQRVAIGRTLVAEPSVFL 156
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 530367936 216 FDEPTTGLDCMTANQIVVLLVELARR-NRIVVLTIHQpRSELFQLFDKIAILSFGELIFCGTPAEM 280
Cdd:PRK11000 157 LDEPLSNLDAALRVQMRIEISRLHKRlGRTMIYVTHD-QVEAMTLADKIVVLDAGRVAQVGKPLEL 221
cbiO PRK13637
energy-coupling factor transporter ATPase;
69-279 1.15e-15

energy-coupling factor transporter ATPase;


Pssm-ID: 237455 [Multi-domain]  Cd Length: 287  Bit Score: 77.40  E-value: 1.15e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  69 LKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGtflGEVYVNG----------RALRRE-----QFQDcfsYVL 133
Cdd:PRK13637  23 LDNVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLKPTS---GKIIIDGvditdkkvklSDIRKKvglvfQYPE---YQL 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 134 QSDTLLSSLtvretlhytALLAIRRG-NPGSFQKKVEAVMAELSLSH--VADRlignySLGGISTGERRRVSIAAQLLQD 210
Cdd:PRK13637  97 FEETIEKDI---------AFGPINLGlSEEEIENRVKRAMNIVGLDYedYKDK-----SPFELSGGQKRRVAIAGVVAME 162
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 530367936 211 PKVMLFDEPTTGLDCMTANQIVVLLVELARRNRIVVLTIHQPRSELFQLFDKIAILSFGELIFCGTPAE 279
Cdd:PRK13637 163 PKILILDEPTAGLDPKGRDEILNKIKELHKEYNMTIILVSHSMEDVAKLADRIIVMNKGKCELQGTPRE 231
ABCC_MRP_domain1 cd03250
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ...
61-266 1.37e-15

ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213217 [Multi-domain]  Cd Length: 204  Bit Score: 75.58  E-value: 1.37e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  61 RQQWTRQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGtflGEVYVNGRalrreqfqdcFSYVLQSDTLLS 140
Cdd:cd03250   13 GEQETSFTLKDINLEVPKGELVAIVGPVGSGKSSLLSALLGELEKLS---GSVSVPGS----------IAYVSQEPWIQN 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 141 SlTVRETlhytallaIRRGNPgsFQKK-----VEA--------VMAELSLSHVADRlignyslgGI--STGERRRVSIAA 205
Cdd:cd03250   80 G-TIREN--------ILFGKP--FDEEryekvIKAcalepdleILPDGDLTEIGEK--------GInlSGGQKQRISLAR 140
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 530367936 206 QLLQDPKVMLFDEPTTGLDCMTANQIV--VLLVELaRRNRIVVLTIHQPrsELFQLFDKIAIL 266
Cdd:cd03250  141 AVYSDADIYLLDDPLSAVDAHVGRHIFenCILGLL-LNNKTRILVTHQL--QLLPHADQIVVL 200
PRK11264 PRK11264
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
66-251 2.88e-15

putative amino-acid ABC transporter ATP-binding protein YecC; Provisional


Pssm-ID: 183063 [Multi-domain]  Cd Length: 250  Bit Score: 75.56  E-value: 2.88e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  66 RQILKDVSLYVESGQIMCILGSSGSGKTTLLDAM-------SGRLGragtfLGEVYVNG-RALRREQ-----FQDCFSYV 132
Cdd:PRK11264  16 QTVLHGIDLEVKPGEVVAIIGPSGSGKTTLLRCInlleqpeAGTIR-----VGDITIDTaRSLSQQKglirqLRQHVGFV 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 133 LQSDTLLSSLTVRETLHYTALlaIRRGNP-GSFQKKVEAVMAELSLSHVAD----RLIGnyslggistGERRRVSIAAQL 207
Cdd:PRK11264  91 FQNFNLFPHRTVLENIIEGPV--IVKGEPkEEATARARELLAKVGLAGKETsyprRLSG---------GQQQRVAIARAL 159
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 530367936 208 LQDPKVMLFDEPTTGLDCMTANQIVVLLVELARRNRIVVLTIHQ 251
Cdd:PRK11264 160 AMRPEVILFDEPTSALDPELVGEVLNTIRQLAQEKRTMVIVTHE 203
glnQ PRK09493
glutamine ABC transporter ATP-binding protein GlnQ;
67-282 3.80e-15

glutamine ABC transporter ATP-binding protein GlnQ;


Pssm-ID: 181906 [Multi-domain]  Cd Length: 240  Bit Score: 75.13  E-value: 3.80e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  67 QILKDVSLYVESGQIMCILGSSGSGKTTLLDAM-------SGRLGRAGTFLGEVYVNGRALRREQfqdcfSYVLQSDTLL 139
Cdd:PRK09493  15 QVLHNIDLNIDQGEVVVIIGPSGSGKSTLLRCInkleeitSGDLIVDGLKVNDPKVDERLIRQEA-----GMVFQQFYLF 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 140 SSLTVRETLHYTALlAIRRGNPGSFQKKVEAVMAELSLSHVAdrligNYSLGGISTGERRRVSIAAQLLQDPKVMLFDEP 219
Cdd:PRK09493  90 PHLTALENVMFGPL-RVRGASKEEAEKQARELLAKVGLAERA-----HHYPSELSGGQQQRVAIARALAVKPKLMLFDEP 163
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 530367936 220 TTGLDCMTANQIVVLLVELARRNRIVVLTIHQprselFQLFDKIAilsfGELIFC--------GTPAEMLD 282
Cdd:PRK09493 164 TSALDPELRHEVLKVMQDLAEEGMTMVIVTHE-----IGFAEKVA----SRLIFIdkgriaedGDPQVLIK 225
PRK14247 PRK14247
phosphate ABC transporter ATP-binding protein; Provisional
67-281 6.11e-15

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172735 [Multi-domain]  Cd Length: 250  Bit Score: 74.95  E-value: 6.11e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  67 QILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSG--RLGRAGTFLGEVYVNGRAL---------RREQFqdcfsyVLQS 135
Cdd:PRK14247  17 EVLDGVNLEIPDNTITALMGPSGSGKSTLLRVFNRliELYPEARVSGEVYLDGQDIfkmdvielrRRVQM------VFQI 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 136 DTLLSSLTVRETLHYTALLAIRRGNPGSFQKKVEAVMAELSL-SHVADRLigNYSLGGISTGERRRVSIAAQLLQDPKVM 214
Cdd:PRK14247  91 PNPIPNLSIFENVALGLKLNRLVKSKKELQERVRWALEKAQLwDEVKDRL--DAPAGKLSGGQQQRLCIARALAFQPEVL 168
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 530367936 215 LFDEPTTGLDCMTANQIVVLLVELARRNRIVVLTiHQPrSELFQLFDKIAILSFGELIFCGTPAEML 281
Cdd:PRK14247 169 LADEPTANLDPENTAKIESLFLELKKDMTIVLVT-HFP-QQAARISDYVAFLYKGQIVEWGPTREVF 233
ABC_MTABC3_MDL1_MDL2 cd03249
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ...
67-281 6.61e-15

ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.


Pssm-ID: 213216 [Multi-domain]  Cd Length: 238  Bit Score: 74.50  E-value: 6.61e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  67 QILKDVSLYVESGQIMCILGSSGSGKTTLLdAMSGRLgrAGTFLGEVYVNGRALRR---EQFQDCFSYVLQSDTLLSSlT 143
Cdd:cd03249   17 PILKGLSLTIPPGKTVALVGSSGCGKSTVV-SLLERF--YDPTSGEILLDGVDIRDlnlRWLRSQIGLVSQEPVLFDG-T 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 144 VRETlhytallaIRRGNPGSFQKKVEAV--MAEL-----SLSHVADRLIGNY--SLGGistGERRRVSIAAQLLQDPKVM 214
Cdd:cd03249   93 IAEN--------IRYGKPDATDEEVEEAakKANIhdfimSLPDGYDTLVGERgsQLSG---GQKQRIAIARALLRNPKIL 161
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 530367936 215 LFDEPTTGLDcmTANQIVVL-LVELARRNRIVVLTIHqpRSELFQLFDKIAILSFGELIFCGTPAEML 281
Cdd:cd03249  162 LLDEATSALD--AESEKLVQeALDRAMKGRTTIVIAH--RLSTIRNADLIAVLQNGQVVEQGTHDELM 225
cbiO PRK13643
energy-coupling factor transporter ATPase;
69-294 7.04e-15

energy-coupling factor transporter ATPase;


Pssm-ID: 184203 [Multi-domain]  Cd Length: 288  Bit Score: 75.16  E-value: 7.04e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  69 LKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLG-RAGTF-LGEVYVNGRALRREqfqdcFSYVLQSDTLLSSLTVRE 146
Cdd:PRK13643  22 LFDIDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQpTEGKVtVGDIVVSSTSKQKE-----IKPVRKKVGVVFQFPESQ 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 147 TLHYTALLAIRRG--NPGSFQKKVEAVMAElSLSHVA-DRLIGNYSLGGISTGERRRVSIAAQLLQDPKVMLFDEPTTGL 223
Cdd:PRK13643  97 LFEETVLKDVAFGpqNFGIPKEKAEKIAAE-KLEMVGlADEFWEKSPFELSGGQMRRVAIAGILAMEPEVLVLDEPTAGL 175
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 530367936 224 DCMTANQIVVLLVELARRNRIVVLTIHQpRSELFQLFDKIAILSFGELIFCGTPAEM---LDFF--NDCGYPCPEH 294
Cdd:PRK13643 176 DPKARIEMMQLFESIHQSGQTVVLVTHL-MDDVADYADYVYLLEKGHIISCGTPSDVfqeVDFLkaHELGVPKATH 250
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
65-224 9.01e-15

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 77.03  E-value: 9.01e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  65 TRQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGtflGEVYVNGRaLRreqfqdcFSYVLQSDTLLSSLTV 144
Cdd:COG0488   10 GRPLLDDVSLSINPGDRIGLVGRNGAGKSTLLKILAGELEPDS---GEVSIPKG-LR-------IGYLPQEPPLDDDLTV 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 145 RETL-----------------------------HYTALLA-IRRGNPGSFQKKVEAVMAELSLSHV-ADRLIGNYSlgGi 193
Cdd:COG0488   79 LDTVldgdaelraleaeleeleaklaepdedleRLAELQEeFEALGGWEAEARAEEILSGLGFPEEdLDRPVSELS--G- 155
                        170       180       190
                 ....*....|....*....|....*....|.
gi 530367936 194 stGERRRVSIAAQLLQDPKVMLFDEPTTGLD 224
Cdd:COG0488  156 --GWRRRVALARALLSEPDLLLLDEPTNHLD 184
HisP COG4598
ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];
67-224 1.28e-14

ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];


Pssm-ID: 443652 [Multi-domain]  Cd Length: 259  Bit Score: 74.07  E-value: 1.28e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  67 QILKDVSLYVESGQIMCILGSSGSGKTTLLdamsgrlgRAGTFL-----GEVYVNGRALR-------------REQFQDC 128
Cdd:COG4598   22 EVLKGVSLTARKGDVISIIGSSGSGKSTFL--------RCINLLetpdsGEIRVGGEEIRlkpdrdgelvpadRRQLQRI 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 129 ---FSYVLQSDTLLSSLTVRET-----LHytaLLAIRRGNPgsfQKKVEAVMAELSLSHVADrlignYSLGGISTGERRR 200
Cdd:COG4598   94 rtrLGMVFQSFNLWSHMTVLENvieapVH---VLGRPKAEA---IERAEALLAKVGLADKRD-----AYPAHLSGGQQQR 162
                        170       180
                 ....*....|....*....|....
gi 530367936 201 VSIAAQLLQDPKVMLFDEPTTGLD 224
Cdd:COG4598  163 AAIARALAMEPEVMLFDEPTSALD 186
PRK14267 PRK14267
phosphate ABC transporter ATP-binding protein; Provisional
67-294 1.57e-14

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184596 [Multi-domain]  Cd Length: 253  Bit Score: 73.72  E-value: 1.57e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  67 QILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSG--RLGRAGTFLGEVYVNGRALRRE-----QFQDCFSYVLQSDTLL 139
Cdd:PRK14267  18 HVIKGVDLKIPQNGVFALMGPSGCGKSTLLRTFNRllELNEEARVEGEVRLFGRNIYSPdvdpiEVRREVGMVFQYPNPF 97
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 140 SSLTVRET----LHYTALLAIRrgnpGSFQKKVEAVMAELSL-SHVADRLigNYSLGGISTGERRRVSIAAQLLQDPKVM 214
Cdd:PRK14267  98 PHLTIYDNvaigVKLNGLVKSK----KELDERVEWALKKAALwDEVKDRL--NDYPSNLSGGQRQRLVIARALAMKPKIL 171
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 215 LFDEPTTGLDCMTANQIVVLLVELARRNRIVVLTiHQPrSELFQLFDKIAILSFGELIFCGtPAEMLdFFNdcgypcPEH 294
Cdd:PRK14267 172 LMDEPTANIDPVGTAKIEELLFELKKEYTIVLVT-HSP-AQAARVSDYVAFLYLGKLIEVG-PTRKV-FEN------PEH 241
PRK13536 PRK13536
nodulation factor ABC transporter ATP-binding protein NodI;
68-282 1.87e-14

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237419 [Multi-domain]  Cd Length: 340  Bit Score: 74.87  E-value: 1.87e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  68 ILKDVSLYVESGQIMCILGSSGSGKTT----LLDAMSGRLGRAgTFLGE-VYVNGRALRREqfqdcFSYVLQSDTLLSSL 142
Cdd:PRK13536  56 VVNGLSFTVASGECFGLLGPNGAGKSTiarmILGMTSPDAGKI-TVLGVpVPARARLARAR-----IGVVPQFDNLDLEF 129
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 143 TVRETL----HYTALLAirrgnpgsfqKKVEAVMAEL----SLSHVADRLIGNyslggISTGERRRVSIAAQLLQDPKVM 214
Cdd:PRK13536 130 TVRENLlvfgRYFGMST----------REIEAVIPSLlefaRLESKADARVSD-----LSGGMKRRLTLARALINDPQLL 194
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 530367936 215 LFDEPTTGLDCMTANQIVVLLVELARRNRIVVLTIHQpRSELFQLFDKIAILSFGELIFCGTPAEMLD 282
Cdd:PRK13536 195 ILDEPTTGLDPHARHLIWERLRSLLARGKTILLTTHF-MEEAERLCDRLCVLEAGRKIAEGRPHALID 261
PRK11174 PRK11174
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
67-279 2.97e-14

cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed


Pssm-ID: 236870 [Multi-domain]  Cd Length: 588  Bit Score: 75.65  E-value: 2.97e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  67 QILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGrlgragtFL---GEVYVNG---RALRREQFQDCFSYVLQSDTLLS 140
Cdd:PRK11174 364 TLAGPLNFTLPAGQRIALVGPSGAGKTSLLNALLG-------FLpyqGSLKINGielRELDPESWRKHLSWVGQNPQLPH 436
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 141 SlTVRETLhytaLLairrGNPGSFQKKVEAVMAELSLSHVADRL-------IGNYSlGGISTGERRRVSIAAQLLQDPKV 213
Cdd:PRK11174 437 G-TLRDNV----LL----GNPDASDEQLQQALENAWVSEFLPLLpqgldtpIGDQA-AGLSVGQAQRLALARALLQPCQL 506
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 530367936 214 MLFDEPTTGLDCMTANQIVVLLVELARRNRIVVLTiHQprseLFQL--FDKIAILSFGELIFCGTPAE 279
Cdd:PRK11174 507 LLLDEPTASLDAHSEQLVMQALNAASRRQTTLMVT-HQ----LEDLaqWDQIWVMQDGQIVQQGDYAE 569
YejF COG4172
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...
69-241 3.33e-14

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443332 [Multi-domain]  Cd Length: 533  Bit Score: 75.11  E-value: 3.33e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  69 LKDVSLYVESGQIMCILGSSGSGKTTLLDAMSgRLGRAGtflGEVYVNG-----------RALRRE-Q--FQDCFSyvlq 134
Cdd:COG4172  302 VDGVSLTLRRGETLGLVGESGSGKSTLGLALL-RLIPSE---GEIRFDGqdldglsrralRPLRRRmQvvFQDPFG---- 373
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 135 sdtllsSL----TVRET------LHYTALLAIRRgnpgsfQKKVEAVMAELSLSH-VADRLIGNYSlgGistGERRRVSI 203
Cdd:COG4172  374 ------SLsprmTVGQIiaeglrVHGPGLSAAER------RARVAEALEEVGLDPaARHRYPHEFS--G---GQRQRIAI 436
                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 530367936 204 AAQLLQDPKVMLFDEPTTGLDCMTANQIVVLLVELARR 241
Cdd:COG4172  437 ARALILEPKLLVLDEPTSALDVSVQAQILDLLRDLQRE 474
PRK13537 PRK13537
nodulation factor ABC transporter ATP-binding protein NodI;
68-282 4.81e-14

nodulation factor ABC transporter ATP-binding protein NodI;


Pssm-ID: 237420 [Multi-domain]  Cd Length: 306  Bit Score: 72.92  E-value: 4.81e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  68 ILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSG-RLGRAGT--FLGEVyVNGRALRREQFqdcFSYVLQSDTLLSSLTV 144
Cdd:PRK13537  22 VVDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGlTHPDAGSisLCGEP-VPSRARHARQR---VGVVPQFDNLDPDFTV 97
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 145 RETL----HYTALLAirrgnpGSFQKKVEAVMAELSLSHVADRLIGNyslggISTGERRRVSIAAQLLQDPKVMLFDEPT 220
Cdd:PRK13537  98 RENLlvfgRYFGLSA------AAARALVPPLLEFAKLENKADAKVGE-----LSGGMKRRLTLARALVNDPDVLVLDEPT 166
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 530367936 221 TGLDCMTANQIVVLLVELARRNRIVVLTIHQpRSELFQLFDKIAILSFGELIFCGTPAEMLD 282
Cdd:PRK13537 167 TGLDPQARHLMWERLRSLLARGKTILLTTHF-MEEAERLCDRLCVIEEGRKIAEGAPHALIE 227
cbiO PRK13652
cobalt transporter ATP-binding subunit; Provisional
65-280 5.51e-14

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 172200 [Multi-domain]  Cd Length: 277  Bit Score: 72.53  E-value: 5.51e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  65 TRQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGtflGEVYVNGRALRREQFQDCFSYV----LQSDTLLS 140
Cdd:PRK13652  16 SKEALNNINFIAPRNSRIAVIGPNGAGKSTLFRHFNGILKPTS---GSVLIRGEPITKENIREVRKFVglvfQNPDDQIF 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 141 SLTVRETLhytALLAIRRG-NPGSFQKKVEAVMAELSLSHVADRLIGNyslggISTGERRRVSIAAQLLQDPKVMLFDEP 219
Cdd:PRK13652  93 SPTVEQDI---AFGPINLGlDEETVAHRVSSALHMLGLEELRDRVPHH-----LSGGEKKRVAIAGVIAMEPQVLVLDEP 164
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 530367936 220 TTGLDCMTANQIVVLLVELARR-NRIVVLTIHQpRSELFQLFDKIAILSFGELIFCGTPAEM 280
Cdd:PRK13652 165 TAGLDPQGVKELIDFLNDLPETyGMTVIFSTHQ-LDLVPEMADYIYVMDKGRIVAYGTVEEI 225
PRK14239 PRK14239
phosphate transporter ATP-binding protein; Provisional
66-300 6.61e-14

phosphate transporter ATP-binding protein; Provisional


Pssm-ID: 184585 [Multi-domain]  Cd Length: 252  Bit Score: 71.73  E-value: 6.61e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  66 RQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMS--GRLGRAGTFLGEVYVNGR----------ALRREqfqdcFSYVL 133
Cdd:PRK14239  18 KKALNSVSLDFYPNEITALIGPSGSGKSTLLRSINrmNDLNPEVTITGSIVYNGHniysprtdtvDLRKE-----IGMVF 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 134 QSDTLLSsLTVRETLHYTALLAirrgnpGSFQKKV--EAVmaELSL------SHVADRLigNYSLGGISTGERRRVSIAA 205
Cdd:PRK14239  93 QQPNPFP-MSIYENVVYGLRLK------GIKDKQVldEAV--EKSLkgasiwDEVKDRL--HDSALGLSGGQQQRVCIAR 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 206 QLLQDPKVMLFDEPTTGLDCMTANQIVVLLVELarRNRIVVLTIHQPRSELFQLFDKIAILSFGELIFCGTPAEMldFFN 285
Cdd:PRK14239 162 VLATSPKIILLDEPTSALDPISAGKIEETLLGL--KDDYTMLLVTRSMQQASRISDRTGFFLDGDLIEYNDTKQM--FMN 237
                        250
                 ....*....|....*
gi 530367936 286 dcgypcPEHSNPFDF 300
Cdd:PRK14239 238 ------PKHKETEDY 246
NupO COG3845
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...
69-223 7.61e-14

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];


Pssm-ID: 443055 [Multi-domain]  Cd Length: 504  Bit Score: 73.91  E-value: 7.61e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  69 LKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGrlgragtFL----GEVYVNGRALRREQFQDCFSY----VLQSDTLLS 140
Cdd:COG3845   21 NDDVSLTVRPGEIHALLGENGAGKSTLMKILYG-------LYqpdsGEILIDGKPVRIRSPRDAIALgigmVHQHFMLVP 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 141 SLTVRETLhytaLLAIRRGNPGSF-----QKKVEAVMAELSLSHVADRLIGNyslggISTGERRRVSIAAQLLQDPKVML 215
Cdd:COG3845   94 NLTVAENI----VLGLEPTKGGRLdrkaaRARIRELSERYGLDVDPDAKVED-----LSVGEQQRVEILKALYRGARILI 164

                 ....*...
gi 530367936 216 FDEPTTGL 223
Cdd:COG3845  165 LDEPTAVL 172
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
69-280 8.42e-14

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 73.90  E-value: 8.42e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  69 LKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLgRAGTflGEVYVNGRALRREQFQDCF----SYVLQSDTLLSSLTV 144
Cdd:COG1129   20 LDGVSLELRPGEVHALLGENGAGKSTLMKILSGVY-QPDS--GEILLDGEPVRFRSPRDAQaagiAIIHQELNLVPNLSV 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 145 RETLhYTALLAIRRG--NPGSFQKKVEAVMAELSLSHVADRLIGNYSLggistGERRRVSIAAQLLQDPKVMLFDEPTTG 222
Cdd:COG1129   97 AENI-FLGREPRRGGliDWRAMRRRARELLARLGLDIDPDTPVGDLSV-----AQQQLVEIARALSRDARVLILDEPTAS 170
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 530367936 223 LdcmTANQIVVLLV---ELARRNRIVVLTIHqpR-SELFQLFDKIAILSFGELIFCGTPAEM 280
Cdd:COG1129  171 L---TEREVERLFRiirRLKAQGVAIIYISH--RlDEVFEIADRVTVLRDGRLVGTGPVAEL 227
xylG TIGR02633
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...
34-286 1.33e-13

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 131681 [Multi-domain]  Cd Length: 500  Bit Score: 73.32  E-value: 1.33e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936   34 EPHSLG--ILHASYSVShrvrpwWDITSCRqqwtRQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGrlGRAGTFLG 111
Cdd:TIGR02633 249 EPHEIGdvILEARNLTC------WDVINPH----RKRVDDVSFSLRRGEILGVAGLVGAGRTELVQALFG--AYPGKFEG 316
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  112 EVYVNGRALRREQFQDCFSYVL-------QSDTLLSSLTVRETLHYTAL---LAIRRGNPGSFQKKVEAVMAELSLSHVA 181
Cdd:TIGR02633 317 NVFINGKPVDIRNPAQAIRAGIamvpedrKRHGIVPILGVGKNITLSVLksfCFKMRIDAAAELQIIGSAIQRLKVKTAS 396
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  182 DRLignySLGGISTGERRRVSIAAQLLQDPKVMLFDEPTTGLDCMTANQIVVLLVELARRNrIVVLTIHQPRSELFQLFD 261
Cdd:TIGR02633 397 PFL----PIGRLSGGNQQKAVLAKMLLTNPRVLILDEPTRGVDVGAKYEIYKLINQLAQEG-VAIIVVSSELAEVLGLSD 471
                         250       260
                  ....*....|....*....|....*
gi 530367936  262 KIAILSFGELifCGtpaemlDFFND 286
Cdd:TIGR02633 472 RVLVIGEGKL--KG------DFVNH 488
PRK11831 PRK11831
phospholipid ABC transporter ATP-binding protein MlaF;
66-280 1.96e-13

phospholipid ABC transporter ATP-binding protein MlaF;


Pssm-ID: 236997 [Multi-domain]  Cd Length: 269  Bit Score: 70.56  E-value: 1.96e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  66 RQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGtflGEVYVNGR---ALRREQFQDC---FSYVLQSDTLL 139
Cdd:PRK11831  20 RCIFDNISLTVPRGKITAIMGPSGIGKTTLLRLIGGQIAPDH---GEILFDGEnipAMSRSRLYTVrkrMSMLFQSGALF 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 140 SSLTVRETLHY-----TALlairrgnPGSFQKKVeaVMaeLSLSHVADRLIGNYSLGGISTGERRRVSIAAQLLQDPKVM 214
Cdd:PRK11831  97 TDMNVFDNVAYplrehTQL-------PAPLLHST--VM--MKLEAVGLRGAAKLMPSELSGGMARRAALARAIALEPDLI 165
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 530367936 215 LFDEPTTGLDCMTANQIVVLLVELARRNRIVVLTIHQPRSELFQLFDKIAILSFGELIFCGTPAEM 280
Cdd:PRK11831 166 MFDEPFVGQDPITMGVLVKLISELNSALGVTCVVVSHDVPEVLSIADHAYIVADKKIVAHGSAQAL 231
livF PRK11614
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
67-281 2.08e-13

high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;


Pssm-ID: 183231 [Multi-domain]  Cd Length: 237  Bit Score: 69.91  E-value: 2.08e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  67 QILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRlGRAGTflGEVYVNGRALRREQ----FQDCFSYVLQSDTLLSSL 142
Cdd:PRK11614  19 QALHEVSLHINQGEIVTLIGANGAGKTTLLGTLCGD-PRATS--GRIVFDGKDITDWQtakiMREAVAIVPEGRRVFSRM 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 143 TVRETLHYTALLAIRRgnpgSFQKKVEAVMAelSLSHVADRLIgnYSLGGISTGERRRVSIAAQLLQDPKVMLFDEPTTG 222
Cdd:PRK11614  96 TVEENLAMGGFFAERD----QFQERIKWVYE--LFPRLHERRI--QRAGTMSGGEQQMLAIGRALMSQPRLLLLDEPSLG 167
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 530367936 223 LDCMTANQIVVLLVELaRRNRIVVLTIHQPRSELFQLFDKIAILSFGELIFCGTPAEML 281
Cdd:PRK11614 168 LAPIIIQQIFDTIEQL-REQGMTIFLVEQNANQALKLADRGYVLENGHVVLEDTGDALL 225
potG PRK11607
putrescine ABC transporter ATP-binding subunit PotG;
71-280 2.11e-13

putrescine ABC transporter ATP-binding subunit PotG;


Pssm-ID: 183226 [Multi-domain]  Cd Length: 377  Bit Score: 71.79  E-value: 2.11e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  71 DVSLYVESGQIMCILGSSGSGKTTLLDAMSGrlgragtF----LGEVYVNGRALRR-EQFQDCFSYVLQSDTLLSSLTVR 145
Cdd:PRK11607  37 DVSLTIYKGEIFALLGASGCGKSTLLRMLAG-------FeqptAGQIMLDGVDLSHvPPYQRPINMMFQSYALFPHMTVE 109
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 146 ETLHYTalLAIRRGNPGSFQKKVEAVMAELSLSHVADRliGNYSLGGistGERRRVSIAAQLLQDPKVMLFDEPTTGLDC 225
Cdd:PRK11607 110 QNIAFG--LKQDKLPKAEIASRVNEMLGLVHMQEFAKR--KPHQLSG---GQRQRVALARSLAKRPKLLLLDEPMGALDK 182
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 530367936 226 MTANQIVVLLVELARRNRIVVLTIHQPRSELFQLFDKIAILSFGELIFCGTPAEM 280
Cdd:PRK11607 183 KLRDRMQLEVVDILERVGVTCVMVTHDQEEAMTMAGRIAIMNRGKFVQIGEPEEI 237
ABC2_perm_RbbA NF033858
ribosome-associated ATPase/putative transporter RbbA;
71-279 2.70e-13

ribosome-associated ATPase/putative transporter RbbA;


Pssm-ID: 468210 [Multi-domain]  Cd Length: 907  Bit Score: 72.85  E-value: 2.70e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  71 DVSLYVESGQIMCILGSSGSGKTT-------LLDAMSGR---LGRagtflgEVYVNGRALRREqfqdcFSYVLQSDTLLS 140
Cdd:NF033858 284 HVSFRIRRGEIFGFLGSNGCGKSTtmkmltgLLPASEGEawlFGQ------PVDAGDIATRRR-----VGYMSQAFSLYG 352
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 141 SLTVRE--TLHytALLairrgnpgsFQ-------KKVEAVMAELSLSHVADRLIGNYSLGgistgERRRVSIAAQLLQDP 211
Cdd:NF033858 353 ELTVRQnlELH--ARL---------FHlpaaeiaARVAEMLERFDLADVADALPDSLPLG-----IRQRLSLAVAVIHKP 416
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 530367936 212 KVMLFDEPTTGLDCMTANQIVVLLVELARRNRIvvlTI----HqprselfqlF-------DKIAILSFGELIFCGTPAE 279
Cdd:NF033858 417 ELLILDEPTSGVDPVARDMFWRLLIELSREDGV---TIfistH---------FmneaercDRISLMHAGRVLASDTPAA 483
ABCC_CFTR1 cd03291
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The ...
68-322 4.24e-13

ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The CFTR subfamily domain 1. The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits, or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.


Pssm-ID: 213258 [Multi-domain]  Cd Length: 282  Bit Score: 69.89  E-value: 4.24e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  68 ILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGtflGEVYVNGRAlrreQFQDCFSYVLQSdtllsslTVRET 147
Cdd:cd03291   52 VLKNINLKIEKGEMLAITGSTGSGKTSLLMLILGELEPSE---GKIKHSGRI----SFSSQFSWIMPG-------TIKEN 117
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 148 LHYTALLAIRRgnpgsFQKKVEAVMAELSLSHVADRLIGNYSLGGI--STGERRRVSIAAQLLQDPKVMLFDEPTTGLDC 225
Cdd:cd03291  118 IIFGVSYDEYR-----YKSVVKACQLEEDITKFPEKDNTVLGEGGItlSGGQRARISLARAVYKDADLYLLDSPFGYLDV 192
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 226 MTANQIVVLLV--ELARRNRIVVLTihqpRSELFQLFDKIAILSFGELIFCGTPAEMLDFFndcgypcPEHSNPFdfyMD 303
Cdd:cd03291  193 FTEKEIFESCVckLMANKTRILVTS----KMEHLKKADKILILHEGSSYFYGTFSELQSLR-------PDFSSKL---MG 258
                        250       260
                 ....*....|....*....|...
gi 530367936 304 LTSVDTQSKERE----IETSKRV 322
Cdd:cd03291  259 YDTFDQFSAERRnsilTETLRRF 281
CFTR_protein TIGR01271
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...
68-280 5.32e-13

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]


Pssm-ID: 273530 [Multi-domain]  Cd Length: 1490  Bit Score: 72.25  E-value: 5.32e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936    68 ILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGtflGEVYVNGRAlrreQFQDCFSYVLQS---DTLLSSLTV 144
Cdd:TIGR01271  441 VLKNISFKLEKGQLLAVAGSTGSGKSSLLMMIMGELEPSE---GKIKHSGRI----SFSPQTSWIMPGtikDNIIFGLSY 513
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936   145 REtLHYTALlairrgnpgsfqkkVEAVMAELSLSHVADRLIGNYSLGGI--STGERRRVSIAAQLLQDPKVMLFDEPTTG 222
Cdd:TIGR01271  514 DE-YRYTSV--------------IKACQLEEDIALFPEKDKTVLGEGGItlSGGQRARISLARAVYKDADLYLLDSPFTH 578
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936   223 LDCMTANQIV--VLLVELARRNRIVVLTihqpRSELFQLFDKIAILSFGELIFCGTPAEM 280
Cdd:TIGR01271  579 LDVVTEKEIFesCLCKLMSNKTRILVTS----KLEHLKKADKILLLHEGVCYFYGTFSEL 634
fbpC PRK11432
ferric ABC transporter ATP-binding protein;
68-280 7.08e-13

ferric ABC transporter ATP-binding protein;


Pssm-ID: 183133 [Multi-domain]  Cd Length: 351  Bit Score: 70.13  E-value: 7.08e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  68 ILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGrLGRAGTflGEVYVNGRALRREQFQD---CFsyVLQSDTLLSSLTV 144
Cdd:PRK11432  21 VIDNLNLTIKQGTMVTLLGPSGCGKTTVLRLVAG-LEKPTE--GQIFIDGEDVTHRSIQQrdiCM--VFQSYALFPHMSL 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 145 RETLHYTalLAIRRGNPGSFQKKVEAVMAELSLSHVADRLIGNyslggISTGERRRVSIAAQLLQDPKVMLFDEPTTGLD 224
Cdd:PRK11432  96 GENVGYG--LKMLGVPKEERKQRVKEALELVDLAGFEDRYVDQ-----ISGGQQQRVALARALILKPKVLLFDEPLSNLD 168
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 530367936 225 CMTANQIVVLLVELARRNRIVVLTIHQPRSELFQLFDKIAILSFGELIFCGTPAEM 280
Cdd:PRK11432 169 ANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDTVIVMNKGKIMQIGSPQEL 224
ABC_FeS_Assembly cd03217
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ...
66-289 7.17e-13

ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.


Pssm-ID: 213184 [Multi-domain]  Cd Length: 200  Bit Score: 67.55  E-value: 7.17e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  66 RQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGTfLGEVYVNGralrreqfQDcfsyvlqsdtlLSSLTVR 145
Cdd:cd03217   13 KEILKGVNLTIKKGEVHALMGPNGSGKSTLAKTIMGHPKYEVT-EGEILFKG--------ED-----------ITDLPPE 72
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 146 ETlhytallaIRRGNPGSFQKKVEavMAELSLSHVADRLigNYslgGISTGERRRVSIAAQLLQDPKVMLFDEPTTGLDC 225
Cdd:cd03217   73 ER--------ARLGIFLAFQYPPE--IPGVKNADFLRYV--NE---GFSGGEKKRNEILQLLLLEPDLAILDEPDSGLDI 137
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 530367936 226 MTANQIVVLLVELARRNRIVVLTIHQPRSELFQLFDKIAILSFGELIFCGtPAEMLDFFNDCGY 289
Cdd:cd03217  138 DALRLVAEVINKLREEGKSVLIITHYQRLLDYIKPDRVHVLYDGRIVKSG-DKELALEIEKKGY 200
PRK13540 PRK13540
cytochrome c biogenesis protein CcmA; Provisional
68-251 1.22e-12

cytochrome c biogenesis protein CcmA; Provisional


Pssm-ID: 184127 [Multi-domain]  Cd Length: 200  Bit Score: 66.90  E-value: 1.22e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  68 ILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGtflGEVYVNGRALRREQ--FQDCFSYVLQSDTLLSSLTVR 145
Cdd:PRK13540  16 LLQQISFHLPAGGLLHLKGSNGAGKTTLLKLIAGLLNPEK---GEILFERQSIKKDLctYQKQLCFVGHRSGINPYLTLR 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 146 ETLHYTalLAIRRGNPGsfqkkVEAVMAELSLSHVADrlignYSLGGISTGERRRVSIAAQLLQDPKVMLFDEPTTGLDC 225
Cdd:PRK13540  93 ENCLYD--IHFSPGAVG-----ITELCRLFSLEHLID-----YPCGLLSSGQKRQVALLRLWMSKAKLWLLDEPLVALDE 160
                        170       180
                 ....*....|....*....|....*.
gi 530367936 226 MTANQIVVLLVELARRNRIVVLTIHQ 251
Cdd:PRK13540 161 LSLLTIITKIQEHRAKGGAVLLTSHQ 186
potA PRK09452
spermidine/putrescine ABC transporter ATP-binding protein PotA;
65-279 1.66e-12

spermidine/putrescine ABC transporter ATP-binding protein PotA;


Pssm-ID: 236523 [Multi-domain]  Cd Length: 375  Bit Score: 69.21  E-value: 1.66e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  65 TRQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGrlgragtF----LGEVYVNGRALRR---EQFQdcFSYVLQSDT 137
Cdd:PRK09452  26 GKEVISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAG-------FetpdSGRIMLDGQDITHvpaENRH--VNTVFQSYA 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 138 LLSSLTVRETLHYtALLAIRRGNPgSFQKKVEAVMAELSLSHVADRLIGNyslggISTGERRRVSIAAQLLQDPKVMLFD 217
Cdd:PRK09452  97 LFPHMTVFENVAF-GLRMQKTPAA-EITPRVMEALRMVQLEEFAQRKPHQ-----LSGGQQQRVAIARAVVNKPKVLLLD 169
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 530367936 218 EPTTGLDCMTANQIVVLLVELARRNRIVVLTIHQPRSELFQLFDKIAILSFGELIFCGTPAE 279
Cdd:PRK09452 170 ESLSALDYKLRKQMQNELKALQRKLGITFVFVTHDQEEALTMSDRIVVMRDGRIEQDGTPRE 231
PRK09700 PRK09700
D-allose ABC transporter ATP-binding protein AlsA;
70-271 1.73e-12

D-allose ABC transporter ATP-binding protein AlsA;


Pssm-ID: 182036 [Multi-domain]  Cd Length: 510  Bit Score: 69.81  E-value: 1.73e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  70 KDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGtflGEVYVNGRALR----REQFQDCFSYVLQS---DTLLSSL 142
Cdd:PRK09700 280 RDISFSVCRGEILGFAGLVGSGRTELMNCLFGVDKRAG---GEIRLNGKDISprspLDAVKKGMAYITESrrdNGFFPNF 356
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 143 TVRETLHYTALLAIRR--GNPGSFQKKVEAVMAELSLSHVADRLIG-NYSLGGISTGERRRVSIAAQLLQDPKVMLFDEP 219
Cdd:PRK09700 357 SIAQNMAISRSLKDGGykGAMGLFHEVDEQRTAENQRELLALKCHSvNQNITELSGGNQQKVLISKWLCCCPEVIIFDEP 436
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 530367936 220 TTGLDCMTANQIVVLLVELARRNrIVVLTIHQPRSELFQLFDKIAILSFGEL 271
Cdd:PRK09700 437 TRGIDVGAKAEIYKVMRQLADDG-KVILMVSSELPEIITVCDRIAVFCEGRL 487
ABCC_MRP_domain2 cd03244
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ...
68-277 1.95e-12

ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213211 [Multi-domain]  Cd Length: 221  Bit Score: 66.75  E-value: 1.95e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  68 ILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGtflGEVYVNGR---ALRREQFQDCFSYVLQsDTLLSSLTV 144
Cdd:cd03244   19 VLKNISFSIKPGEKVGIVGRTGSGKSSLLLALFRLVELSS---GSILIDGVdisKIGLHDLRSRISIIPQ-DPVLFSGTI 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 145 RETL----HYTallairrgnpgsfQKKVEAVMAELSL-SHVADRLIGNYSL---GG--ISTGERRRVSIAAQLLQDPKVM 214
Cdd:cd03244   95 RSNLdpfgEYS-------------DEELWQALERVGLkEFVESLPGGLDTVveeGGenLSVGQRQLLCLARALLRKSKIL 161
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 530367936 215 LFDEPTTGLDCMTANQIVVLLVElARRNRIvVLTI-HqpRSELFQLFDKIAILSFGELIFCGTP 277
Cdd:cd03244  162 VLDEATASVDPETDALIQKTIRE-AFKDCT-VLTIaH--RLDTIIDSDRILVLDKGRVVEFDSP 221
oppD PRK09473
oligopeptide transporter ATP-binding component; Provisional
71-250 2.22e-12

oligopeptide transporter ATP-binding component; Provisional


Pssm-ID: 181888 [Multi-domain]  Cd Length: 330  Bit Score: 68.21  E-value: 2.22e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  71 DVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGTFLGEVYVNGRA-----------LRREQ----FQDCFSyvlqs 135
Cdd:PRK09473  34 DLNFSLRAGETLGIVGESGSGKSQTAFALMGLLAANGRIGGSATFNGREilnlpekelnkLRAEQismiFQDPMT----- 108
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 136 dTLLSSLTVRETLHYTALLAIRRGNPGSFQKKV---EAV-MAElslshvADRLIGNYSlGGISTGERRRVSIAAQLLQDP 211
Cdd:PRK09473 109 -SLNPYMRVGEQLMEVLMLHKGMSKAEAFEESVrmlDAVkMPE------ARKRMKMYP-HEFSGGMRQRVMIAMALLCRP 180
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 530367936 212 KVMLFDEPTTGLDCMTANQIVVLLVELARR-NRIVVLTIH 250
Cdd:PRK09473 181 KLLIADEPTTALDVTVQAQIMTLLNELKREfNTAIIMITH 220
cbiO PRK13635
energy-coupling factor ABC transporter ATP-binding protein;
65-279 3.16e-12

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184195 [Multi-domain]  Cd Length: 279  Bit Score: 67.35  E-value: 3.16e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  65 TRQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGtflGEVYVNGRALRREQFQDC---FSYVLQS-DTLLS 140
Cdd:PRK13635  19 ATYALKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLLPEA---GTITVGGMVLSEETVWDVrrqVGMVFQNpDNQFV 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 141 SLTVRETLhytALLAIRRGNPGS-FQKKVEAVMAELSLSHVADRliGNYSLGGistGERRRVSIAAQLLQDPKVMLFDEP 219
Cdd:PRK13635  96 GATVQDDV---AFGLENIGVPREeMVERVDQALRQVGMEDFLNR--EPHRLSG---GQKQRVAIAGVLALQPDIIILDEA 167
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 220 TTGLDCMTANQIVVLLVELARRNRIVVLTIHQPRSELFQLfDKIAILSFGELIFCGTPAE 279
Cdd:PRK13635 168 TSMLDPRGRREVLETVRQLKEQKGITVLSITHDLDEAAQA-DRVIVMNKGEILEEGTPEE 226
phnK PRK11701
phosphonate C-P lyase system protein PhnK; Provisional
65-224 3.37e-12

phosphonate C-P lyase system protein PhnK; Provisional


Pssm-ID: 183280 [Multi-domain]  Cd Length: 258  Bit Score: 66.87  E-value: 3.37e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  65 TRQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRL----------GRAGTFLgEVYVNGRALRREQFQDCFSYVLQ 134
Cdd:PRK11701  18 PRKGCRDVSFDLYPGEVLGIVGESGSGKTTLLNALSARLapdagevhyrMRDGQLR-DLYALSEAERRRLLRTEWGFVHQ 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 135 S--DTLLSSLT----VRETL------HYTALlairRGNPGSFQKKVEAVMAELslshvaDRLIGNYSlGGIstgeRRRVS 202
Cdd:PRK11701  97 HprDGLRMQVSaggnIGERLmavgarHYGDI----RATAGDWLERVEIDAARI------DDLPTTFS-GGM----QQRLQ 161
                        170       180
                 ....*....|....*....|..
gi 530367936 203 IAAQLLQDPKVMLFDEPTTGLD 224
Cdd:PRK11701 162 IARNLVTHPRLVFMDEPTGGLD 183
araG PRK11288
L-arabinose ABC transporter ATP-binding protein AraG;
69-272 3.65e-12

L-arabinose ABC transporter ATP-binding protein AraG;


Pssm-ID: 183077 [Multi-domain]  Cd Length: 501  Bit Score: 68.78  E-value: 3.65e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  69 LKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGrLGRAGTflGEVYVNGRALR----REQFQDCFSYVLQSDTLLSSLTV 144
Cdd:PRK11288  20 LDDISFDCRAGQVHALMGENGAGKSTLLKILSG-NYQPDA--GSILIDGQEMRfastTAALAAGVAIIYQELHLVPEMTV 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 145 RETLhYTALLAIRRGnpgSFQKKVEAVMAELSLSHVADRLIGNYSLGGISTGERRRVSIAAQLLQDPKVMLFDEPTTGLD 224
Cdd:PRK11288  97 AENL-YLGQLPHKGG---IVNRRLLNYEAREQLEHLGVDIDPDTPLKYLSIGQRQMVEIAKALARNARVIAFDEPTSSLS 172
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 530367936 225 CMTANQIVVLLVELARRNRIVVLTIHQpRSELFQLFDKIAILSFGELI 272
Cdd:PRK11288 173 AREIEQLFRVIRELRAEGRVILYVSHR-MEEIFALCDAITVFKDGRYV 219
MglA COG1129
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
65-272 3.84e-12

ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440745 [Multi-domain]  Cd Length: 497  Bit Score: 68.51  E-value: 3.84e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  65 TRQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGtflGEVYVNGRALRREQFQDC----FSYV---LQSDT 137
Cdd:COG1129  264 VGGVVRDVSFSVRAGEILGIAGLVGAGRTELARALFGADPADS---GEIRLDGKPVRIRSPRDAiragIAYVpedRKGEG 340
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 138 LLSSLTVRETLHYTALLAIRRG---NPGSFQKKVEAVMAELSL-SHVADRLIGNYSlgGistGERRRVSIAAQLLQDPKV 213
Cdd:COG1129  341 LVLDLSIRENITLASLDRLSRGgllDRRRERALAEEYIKRLRIkTPSPEQPVGNLS--G---GNQQKVVLAKWLATDPKV 415
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 530367936 214 MLFDEPTTGLDCMTANQIVVLLVELARRNR-IVVLTihqprSEL---FQLFDKIAILSFGELI 272
Cdd:COG1129  416 LILDEPTRGIDVGAKAEIYRLIRELAAEGKaVIVIS-----SELpelLGLSDRILVMREGRIV 473
thiQ PRK10771
thiamine ABC transporter ATP-binding protein ThiQ;
73-249 4.15e-12

thiamine ABC transporter ATP-binding protein ThiQ;


Pssm-ID: 182716 [Multi-domain]  Cd Length: 232  Bit Score: 66.14  E-value: 4.15e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  73 SLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGtflGEVYVNGralrreqfQDC---------FSYVLQSDTLLSSLT 143
Cdd:PRK10771  19 DLTVERGERVAILGPSGAGKSTLLNLIAGFLTPAS---GSLTLNG--------QDHtttppsrrpVSMLFQENNLFSHLT 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 144 VRETLHytalLAIrrgNPG-----SFQKKVEAVMAELSLSHVADRLIGNyslggISTGERRRVSIAAQLLQDPKVMLFDE 218
Cdd:PRK10771  88 VAQNIG----LGL---NPGlklnaAQREKLHAIARQMGIEDLLARLPGQ-----LSGGQRQRVALARCLVREQPILLLDE 155
                        170       180       190
                 ....*....|....*....|....*....|.
gi 530367936 219 PTTGLDCMTANQIVVLLVELARRNRIVVLTI 249
Cdd:PRK10771 156 PFSALDPALRQEMLTLVSQVCQERQLTLLMV 186
cbiO PRK13646
energy-coupling factor transporter ATPase;
56-289 4.26e-12

energy-coupling factor transporter ATPase;


Pssm-ID: 184205 [Multi-domain]  Cd Length: 286  Bit Score: 66.73  E-value: 4.26e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  56 DITSCRQQWT---RQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLgRAGTflGEVYVNG------------RAL 120
Cdd:PRK13646   7 NVSYTYQKGTpyeHQAIHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALL-KPTT--GTVTVDDitithktkdkyiRPV 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 121 RREqfqdcFSYVLQ-SDTLLSSLTV-RETLHytallairrgNPGSFQKKVEAVMA---ELSLSHVADRLIGNYSLGGIST 195
Cdd:PRK13646  84 RKR-----IGMVFQfPESQLFEDTVeREIIF----------GPKNFKMNLDEVKNyahRLLMDLGFSRDVMSQSPFQMSG 148
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 196 GERRRVSIAAQLLQDPKVMLFDEPTTGLDCMTANQIVVLLVELA-RRNRIVVLTIHQpRSELFQLFDKIAILSFGELIFC 274
Cdd:PRK13646 149 GQMRKIAIVSILAMNPDIIVLDEPTAGLDPQSKRQVMRLLKSLQtDENKTIILVSHD-MNEVARYADEVIVMKEGSIVSQ 227
                        250
                 ....*....|....*
gi 530367936 275 GTPAEMldfFNDCGY 289
Cdd:PRK13646 228 TSPKEL---FKDKKK 239
PRK13633 PRK13633
energy-coupling factor transporter ATPase;
69-280 6.86e-12

energy-coupling factor transporter ATPase;


Pssm-ID: 237453 [Multi-domain]  Cd Length: 280  Bit Score: 66.26  E-value: 6.86e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  69 LKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGtflGEVYVNGRALRREQ----FQDCFSYVLQS-DTLLSSLT 143
Cdd:PRK13633  26 LDDVNLEVKKGEFLVILGRNGSGKSTIAKHMNALLIPSE---GKVYVDGLDTSDEEnlwdIRNKAGMVFQNpDNQIVATI 102
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 144 VRETLHYTAL-LAIRrgnPGSFQKKVEAVMAELSLSHVADrlignYSLGGISTGERRRVSIAAQLLQDPKVMLFDEPTTG 222
Cdd:PRK13633 103 VEEDVAFGPEnLGIP---PEEIRERVDESLKKVGMYEYRR-----HAPHLLSGGQKQRVAIAGILAMRPECIIFDEPTAM 174
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 530367936 223 LDCMTANQIVVLLVELARRNRIVVLTIHQPRSELFQLfDKIAILSFGELIFCGTPAEM 280
Cdd:PRK13633 175 LDPSGRREVVNTIKELNKKYGITIILITHYMEEAVEA-DRIIVMDSGKVVMEGTPKEI 231
nikE PRK10419
nickel ABC transporter ATP-binding protein NikE;
40-249 7.13e-12

nickel ABC transporter ATP-binding protein NikE;


Pssm-ID: 236689 [Multi-domain]  Cd Length: 268  Bit Score: 65.86  E-value: 7.13e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  40 ILHASySVSHRVRPWWdiTSCRQQWtRQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGrLGRAGTflGEVYVNGR- 118
Cdd:PRK10419   3 LLNVS-GLSHHYAHGG--LSGKHQH-QTVLNNVSLSLKSGETVALLGRSGCGKSTLARLLVG-LESPSQ--GNVSWRGEp 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 119 --ALRREQ-----------FQDCFSYVLQSDTLLSSLtvRETL-HYTALLAIRRgnpgsfQKKVEAV--MAELSLSHvAD 182
Cdd:PRK10419  76 laKLNRAQrkafrrdiqmvFQDSISAVNPRKTVREII--REPLrHLLSLDKAER------LARASEMlrAVDLDDSV-LD 146
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 530367936 183 RLIGNyslggISTGERRRVSIAAQLLQDPKVMLFDEPTTGLDCMTANQIVVLLVELARRNRIVVLTI 249
Cdd:PRK10419 147 KRPPQ-----LSGGQLQRVCLARALAVEPKLLILDEAVSNLDLVLQAGVIRLLKKLQQQFGTACLFI 208
ABCC_TAP cd03248
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ...
66-271 7.86e-12

ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.


Pssm-ID: 213215 [Multi-domain]  Cd Length: 226  Bit Score: 65.18  E-value: 7.86e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  66 RQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGtflGEVYVNGRALrrEQFQDCF-----SYVLQSDTLLS 140
Cdd:cd03248   27 TLVLQDVSFTLHPGEVTALVGPSGSGKSTVVALLENFYQPQG---GQVLLDGKPI--SQYEHKYlhskvSLVGQEPVLFA 101
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 141 SlTVRETLHYtallairrgnpGSFQKKVEAVMAELSLSHvADRLIGNYSLG----------GISTGERRRVSIAAQLLQD 210
Cdd:cd03248  102 R-SLQDNIAY-----------GLQSCSFECVKEAAQKAH-AHSFISELASGydtevgekgsQLSGGQKQRVAIARALIRN 168
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 530367936 211 PKVMLFDEPTTGLDCMTANQIVVLLVELARRNRIVVLTiHqpRSELFQLFDKIAILSFGEL 271
Cdd:cd03248  169 PQVLILDEATSALDAESEQQVQQALYDWPERRTVLVIA-H--RLSTVERADQILVLDGGRI 226
PRK10253 PRK10253
iron-enterobactin ABC transporter ATP-binding protein;
68-281 1.16e-11

iron-enterobactin ABC transporter ATP-binding protein;


Pssm-ID: 182336 [Multi-domain]  Cd Length: 265  Bit Score: 65.39  E-value: 1.16e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  68 ILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGtflGEVYVNGRALRREQFQDC---FSYVLQSDTLLSSLTV 144
Cdd:PRK10253  22 VAENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMTPAH---GHVWLDGEHIQHYASKEVarrIGLLAQNATTPGDITV 98
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 145 RETL------HYTALLAIRRGNpgsfQKKVEAVMAELSLSHVADRlignySLGGISTGERRRVSIAAQLLQDPKVMLFDE 218
Cdd:PRK10253  99 QELVargrypHQPLFTRWRKED----EEAVTKAMQATGITHLADQ-----SVDTLSGGQRQRAWIAMVLAQETAIMLLDE 169
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 530367936 219 PTTGLDCMTANQIVVLLVELARRNRIVVLTIHQPRSELFQLFDKIAILSFGELIFCGTPAEML 281
Cdd:PRK10253 170 PTTWLDISHQIDLLELLSELNREKGYTLAAVLHDLNQACRYASHLIALREGKIVAQGAPKEIV 232
met_CoM_red_A2 TIGR03269
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ...
72-281 1.22e-11

methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]


Pssm-ID: 132313 [Multi-domain]  Cd Length: 520  Bit Score: 67.13  E-value: 1.22e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936   72 VSLYVESGQIMCILGSSGSGKTTLLDAMSGRL----GRAGTFLGEVYVN---------GRALRR----EQFQDCFSYvlq 134
Cdd:TIGR03269 303 VSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLeptsGEVNVRVGDEWVDmtkpgpdgrGRAKRYigilHQEYDLYPH--- 379
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  135 sDTLLSSLTVRETLHYTALLAIRRG-----NPGSFQKKVEAVmaelsLSHVADRLignyslggiSTGERRRVSIAAQLLQ 209
Cdd:TIGR03269 380 -RTVLDNLTEAIGLELPDELARMKAvitlkMVGFDEEKAEEI-----LDKYPDEL---------SEGERHRVALAQVLIK 444
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  210 DPKVMLFDEPTTGLDCMTANQivvllvelarrnriVVLTIHQPRSELFQLF--------------DKIAILSFGELIFCG 275
Cdd:TIGR03269 445 EPRIVILDEPTGTMDPITKVD--------------VTHSILKAREEMEQTFiivshdmdfvldvcDRAALMRDGKIVKIG 510

                  ....*.
gi 530367936  276 TPAEML 281
Cdd:TIGR03269 511 DPEEIV 516
PRK15112 PRK15112
peptide ABC transporter ATP-binding protein SapF;
69-281 1.35e-11

peptide ABC transporter ATP-binding protein SapF;


Pssm-ID: 185067 [Multi-domain]  Cd Length: 267  Bit Score: 65.20  E-value: 1.35e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  69 LKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGtflGEVYVNGRALrreQFQDcFSYVLQSDTLL-----SSLT 143
Cdd:PRK15112  29 VKPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPTS---GELLIDDHPL---HFGD-YSYRSQRIRMIfqdpsTSLN 101
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 144 VRETLHYTALLAIRRGNPGSFQKKVEAVMAELslshvadRLIG------NYSLGGISTGERRRVSIAAQLLQDPKVMLFD 217
Cdd:PRK15112 102 PRQRISQILDFPLRLNTDLEPEQREKQIIETL-------RQVGllpdhaSYYPHMLAPGQKQRLGLARALILRPKVIIAD 174
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 530367936 218 EPTTGLDCMTANQIVVLLVELARRNRIVVLTIHQPRSELFQLFDKIAILSFGELIFCGTPAEML 281
Cdd:PRK15112 175 EALASLDMSMRSQLINLMLELQEKQGISYIYVTQHLGMMKHISDQVLVMHQGEVVERGSTADVL 238
modC PRK11144
molybdenum ABC transporter ATP-binding protein ModC;
71-272 1.49e-11

molybdenum ABC transporter ATP-binding protein ModC;


Pssm-ID: 182993 [Multi-domain]  Cd Length: 352  Bit Score: 66.05  E-value: 1.49e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  71 DVSLYVESGQIMCILGSSGSGKTTLLDAMSGrLGRAGTflGEVYVNGRALRREQFQDCFS-------YVLQSDTLLSSLT 143
Cdd:PRK11144  16 TVNLTLPAQGITAIFGRSGAGKTSLINAISG-LTRPQK--GRIVLNGRVLFDAEKGICLPpekrrigYVFQDARLFPHYK 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 144 VRETLHYtallAIRRGNPGSFQKKVEAvmaeLSLSHVADRLIGnySLGGistGERRRVSIAAQLLQDPKVMLFDEPTTGL 223
Cdd:PRK11144  93 VRGNLRY----GMAKSMVAQFDKIVAL----LGIEPLLDRYPG--SLSG---GEKQRVAIGRALLTAPELLLMDEPLASL 159
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 530367936 224 DCMTANQIVVLLVELARRNRIVVLTIHQPRSELFQLFDKIAILSFGELI 272
Cdd:PRK11144 160 DLPRKRELLPYLERLAREINIPILYVSHSLDEILRLADRVVVLEQGKVK 208
cbiO PRK13638
energy-coupling factor ABC transporter ATP-binding protein;
64-281 1.97e-11

energy-coupling factor ABC transporter ATP-binding protein;


Pssm-ID: 184198 [Multi-domain]  Cd Length: 271  Bit Score: 64.64  E-value: 1.97e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  64 WTR----QILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGtflGEVYVNGRALR---------REQ----FQ 126
Cdd:PRK13638   8 WFRyqdePVLKGLNLDFSLSPVTGLVGANGCGKSTLFMNLSGLLRPQK---GAVLWQGKPLDyskrgllalRQQvatvFQ 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 127 D----CFSYVLQSDTLLS--SLTVRETlhytallairrgnpgSFQKKVEAVMAELSLSHVADRLIGnyslgGISTGERRR 200
Cdd:PRK13638  85 DpeqqIFYTDIDSDIAFSlrNLGVPEA---------------EITRRVDEALTLVDAQHFRHQPIQ-----CLSHGQKKR 144
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 201 VSIAAQLLQDPKVMLFDEPTTGLDCMTANQIVVLLVELARRNRIVVLTIHQPrSELFQLFDKIAILSFGELIFCGTPAEM 280
Cdd:PRK13638 145 VAIAGALVLQARYLLLDEPTAGLDPAGRTQMIAIIRRIVAQGNHVIISSHDI-DLIYEISDAVYVLRQGQILTHGAPGEV 223

                 .
gi 530367936 281 L 281
Cdd:PRK13638 224 F 224
ABC_KpsT_Wzt cd03220
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ...
65-275 2.12e-11

ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.


Pssm-ID: 213187 [Multi-domain]  Cd Length: 224  Bit Score: 63.71  E-value: 2.12e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  65 TRQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLgraGTFLGEVYVNGRAlrreqfqdcfSYVLQSDT-LLSSLT 143
Cdd:cd03220   34 EFWALKDVSFEVPRGERIGLIGRNGAGKSTLLRLLAGIY---PPDSGTVTVRGRV----------SSLLGLGGgFNPELT 100
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 144 VRETLHYTALLairRGNPGSFQKKVEAVMAELS-LSHVADRLIGNYslggiSTGERRRVSIAAQLLQDPKVMLFDEPTTG 222
Cdd:cd03220  101 GRENIYLNGRL---LGLSRKEIDEKIDEIIEFSeLGDFIDLPVKTY-----SSGMKARLAFAIATALEPDILLIDEVLAV 172
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 530367936 223 LDCMTANQIVVLLVELARRNRIVVLTIHQPRSeLFQLFDKIAILSFGELIFCG 275
Cdd:cd03220  173 GDAAFQEKCQRRLRELLKQGKTVILVSHDPSS-IKRLCDRALVLEKGKIRFDG 224
xylG TIGR02633
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ...
69-282 2.32e-11

D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 131681 [Multi-domain]  Cd Length: 500  Bit Score: 66.00  E-value: 2.32e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936   69 LKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGrLGRAGTFLGEVYVNGRALRREQFQDC----FSYVLQSDTLLSSLTV 144
Cdd:TIGR02633  17 LDGIDLEVRPGECVGLCGENGAGKSTLMKILSG-VYPHGTWDGEIYWSGSPLKASNIRDTeragIVIIHQELTLVPELSV 95
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  145 RET--LHYTALLAIRRGNPGSFQKKVEAVMAELSLSHVAD-RLIGNYSLggistGERRRVSIAAQLLQDPKVMLFDEPTT 221
Cdd:TIGR02633  96 AENifLGNEITLPGGRMAYNAMYLRAKNLLRELQLDADNVtRPVGDYGG-----GQQQLVEIAKALNKQARLLILDEPSS 170
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 530367936  222 GLdcmTANQIVVLL---VELARRNrIVVLTIHQPRSELFQLFDKIAILSFGELIfCGTPAEMLD 282
Cdd:TIGR02633 171 SL---TEKETEILLdiiRDLKAHG-VACVYISHKLNEVKAVCDTICVIRDGQHV-ATKDMSTMS 229
Uup COG0488
ATPase components of ABC transporters with duplicated ATPase domains [General function ...
66-224 2.88e-11

ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];


Pssm-ID: 440254 [Multi-domain]  Cd Length: 520  Bit Score: 65.86  E-value: 2.88e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  66 RQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLG-RAGTFlgevyVNGRALRreqfqdcFSYVLQS-DTLLSSLT 143
Cdd:COG0488  328 KTLLDDLSLRIDRGDRIGLIGPNGAGKSTLLKLLAGELEpDSGTV-----KLGETVK-------IGYFDQHqEELDPDKT 395
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 144 VRETlhytallaIRRGNPGSFQKKVEAVMAELSLS-HVADRLIGnySLGGistGERRRVSIAAQLLQDPKVMLFDEPTTG 222
Cdd:COG0488  396 VLDE--------LRDGAPGGTEQEVRGYLGRFLFSgDDAFKPVG--VLSG---GEKARLALAKLLLSPPNVLLLDEPTNH 462

                 ..
gi 530367936 223 LD 224
Cdd:COG0488  463 LD 464
ABCC_SUR1_N cd03290
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The ...
64-251 3.13e-11

ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The sulfonylurea receptor SUR is an ATP transporter of the ABCC/MRP family with tandem ATPase binding domains. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.


Pssm-ID: 213257 [Multi-domain]  Cd Length: 218  Bit Score: 63.12  E-value: 3.13e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  64 WTRQI--LKDVSLYVESGQIMCILGSSGSGKTTLLDAMsgrLGRAGTFLGEVYVNGRALRREQFQDCFS-------YVLQ 134
Cdd:cd03290   10 WGSGLatLSNINIRIPTGQLTMIVGQVGCGKSSLLLAI---LGEMQTLEGKVHWSNKNESEPSFEATRSrnrysvaYAAQ 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 135 SDTLLSSlTVRETLHYtallairrGNPGSFQKkVEAVMAELSLSHVADRL-------IGNYSLGgISTGERRRVSIAAQL 207
Cdd:cd03290   87 KPWLLNA-TVEENITF--------GSPFNKQR-YKAVTDACSLQPDIDLLpfgdqteIGERGIN-LSGGQRQRICVARAL 155
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 530367936 208 LQDPKVMLFDEPTTGLDCMTANQIVV--LLVELARRNRIVVLTIHQ 251
Cdd:cd03290  156 YQNTNIVFLDDPFSALDIHLSDHLMQegILKFLQDDKRTLVLVTHK 201
MK0520 COG2401
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ...
65-252 3.15e-11

ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];


Pssm-ID: 441957 [Multi-domain]  Cd Length: 222  Bit Score: 63.05  E-value: 3.15e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  65 TRQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGrlgragtflgevyvngrALRREQFQDCFsyVLQSDTLLSSLTV 144
Cdd:COG2401   42 ERYVLRDLNLEIEPGEIVLIVGASGSGKSTLLRLLAG-----------------ALKGTPVAGCV--DVPDNQFGREASL 102
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 145 RETLhytallairrGNPGSFQKKVEaVMAELSLSHVA------DRLignyslggiSTGERRRVSIAAQLLQDPKVMLFDE 218
Cdd:COG2401  103 IDAI----------GRKGDFKDAVE-LLNAVGLSDAVlwlrrfKEL---------STGQKFRFRLALLLAERPKLLVIDE 162
                        170       180       190
                 ....*....|....*....|....*....|....*
gi 530367936 219 PTTGLDCMTANQIVVLLVELARRNRI-VVLTIHQP 252
Cdd:COG2401  163 FCSHLDRQTAKRVARNLQKLARRAGItLVVATHHY 197
cbiO PRK13645
energy-coupling factor transporter ATPase;
69-281 3.44e-11

energy-coupling factor transporter ATPase;


Pssm-ID: 184204 [Multi-domain]  Cd Length: 289  Bit Score: 64.26  E-value: 3.44e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  69 LKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRL--GRAGTFLGEVYVNG--------RALRRE-----QFQDcfsYVL 133
Cdd:PRK13645  27 LNNTSLTFKKNKVTCVIGTTGSGKSTMIQLTNGLIisETGQTIVGDYAIPAnlkkikevKRLRKEiglvfQFPE---YQL 103
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 134 QSDTLLSSLtvretlhytALLAIRRG-NPGSFQKKVEAVMAELSLShvadRLIGNYSLGGISTGERRRVSIAAQLLQDPK 212
Cdd:PRK13645 104 FQETIEKDI---------AFGPVNLGeNKQEAYKKVPELLKLVQLP----EDYVKRSPFELSGGQKRRVALAGIIAMDGN 170
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 530367936 213 VMLFDEPTTGLDCMTANQIVVLLVELARRNRIVVLTIHQPRSELFQLFDKIAILSFGELIFCGTPAEML 281
Cdd:PRK13645 171 TLVLDEPTGGLDPKGEEDFINLFERLNKEYKKRIIMVTHNMDQVLRIADEVIVMHEGKVISIGSPFEIF 239
PRK10762 PRK10762
D-ribose transporter ATP binding protein; Provisional
69-272 3.68e-11

D-ribose transporter ATP binding protein; Provisional


Pssm-ID: 236755 [Multi-domain]  Cd Length: 501  Bit Score: 65.41  E-value: 3.68e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  69 LKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGR-AGT--FLG-EVYVNGralRREQFQDCFSYVLQSDTLLSSLTV 144
Cdd:PRK10762  20 LSGAALNVYPGRVMALVGENGAGKSTMMKVLTGIYTRdAGSilYLGkEVTFNG---PKSSQEAGIGIIHQELNLIPQLTI 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 145 RETLhytaLLAIRRGNP-GSFQ-KKV----EAVMAELSLSHVADRLIGNYSLggistGERRRVSIAAQLLQDPKVMLFDE 218
Cdd:PRK10762  97 AENI----FLGREFVNRfGRIDwKKMyaeaDKLLARLNLRFSSDKLVGELSI-----GEQQMVEIAKVLSFESKVIIMDE 167
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 530367936 219 PTTGL-DCMTANQIVVlLVELARRNRIVVLTIHQPRsELFQLFDKIAILSFGELI 272
Cdd:PRK10762 168 PTDALtDTETESLFRV-IRELKSQGRGIVYISHRLK-EIFEICDDVTVFRDGQFI 220
PRK15134 PRK15134
microcin C ABC transporter ATP-binding protein YejF; Provisional
61-269 4.17e-11

microcin C ABC transporter ATP-binding protein YejF; Provisional


Pssm-ID: 237917 [Multi-domain]  Cd Length: 529  Bit Score: 65.50  E-value: 4.17e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  61 RQQWTRQILKDVSLYVESGQIMCILGSSGSGKT-TLLDAMsgRLGRAGTFL---GEVYVNG-----------RALRREQF 125
Cdd:PRK15134  17 QQQTVRTVVNDVSLQIEAGETLALVGESGSGKSvTALSIL--RLLPSPPVVypsGDIRFHGesllhaseqtlRGVRGNKI 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 126 QDCFSYVLQSdtlLSSLTVRETLHYTaLLAIRRGnpgsfqKKVEAVMAEL-------SLSHVADRLiGNYSlGGISTGER 198
Cdd:PRK15134  95 AMIFQEPMVS---LNPLHTLEKQLYE-VLSLHRG------MRREAARGEIlncldrvGIRQAAKRL-TDYP-HQLSGGER 162
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 530367936 199 RRVSIAAQLLQDPKVMLFDEPTTGLDCMTANQIVVLLVELARRNRIVVLTIHQPRSELFQLFDKIAILSFG 269
Cdd:PRK15134 163 QRVMIAMALLTRPELLIADEPTTALDVSVQAQILQLLRELQQELNMGLLFITHNLSIVRKLADRVAVMQNG 233
YejF COG4172
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ...
65-249 4.88e-11

ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443332 [Multi-domain]  Cd Length: 533  Bit Score: 65.09  E-value: 4.88e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  65 TRQILKDVSLYVESGQIMCILGSSGSGKT-TLLDAMsgRL--GRAGTFLGEVYVNG--------RALRREQ-------FQ 126
Cdd:COG4172   22 TVEAVKGVSFDIAAGETLALVGESGSGKSvTALSIL--RLlpDPAAHPSGSILFDGqdllglseRELRRIRgnriamiFQ 99
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 127 DCfsyvlqsdtlLSSLT--------VRETLhytallAIRRGNPGsfqKKVEAVMAELsLSHV----ADRLIGNY--SLGG 192
Cdd:COG4172  100 EP----------MTSLNplhtigkqIAEVL------RLHRGLSG---AAARARALEL-LERVgipdPERRLDAYphQLSG 159
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 530367936 193 istGERRRVSIAAQLLQDPKVMLFDEPTTGLDCMTANQIVVLLVELARRNRIVVLTI 249
Cdd:COG4172  160 ---GQRQRVMIAMALANEPDLLIADEPTTALDVTVQAQILDLLKDLQRELGMALLLI 213
TagH COG1134
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ...
65-286 5.15e-11

ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];


Pssm-ID: 440749 [Multi-domain]  Cd Length: 245  Bit Score: 63.18  E-value: 5.15e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  65 TRQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMsgrlgrAGTFL---GEVYVNGRAlrreqfqdcfsyvlqsDTLLS- 140
Cdd:COG1134   38 EFWALKDVSFEVERGESVGIIGRNGAGKSTLLKLI------AGILEptsGRVEVNGRV----------------SALLEl 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 141 ------SLTVRETLHYTALLAirrgnpGSFQKKVEAVM---AELS-LSHVADRLIGNYslggiSTGERRRV--SIAAQLl 208
Cdd:COG1134   96 gagfhpELTGRENIYLNGRLL------GLSRKEIDEKFdeiVEFAeLGDFIDQPVKTY-----SSGMRARLafAVATAV- 163
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 209 qDPKVMLFDEpttgldcmtanqivVLLV--------------ELARRNRIVVLTIHQPRSeLFQLFDKIAILSFGELIFC 274
Cdd:COG1134  164 -DPDILLVDE--------------VLAVgdaafqkkclarirELRESGRTVIFVSHSMGA-VRRLCDRAIWLEKGRLVMD 227
                        250
                 ....*....|..
gi 530367936 275 GTPAEMLDFFND 286
Cdd:COG1134  228 GDPEEVIAAYEA 239
PLN03232 PLN03232
ABC transporter C family member; Provisional
55-280 5.22e-11

ABC transporter C family member; Provisional


Pssm-ID: 215640 [Multi-domain]  Cd Length: 1495  Bit Score: 65.77  E-value: 5.22e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936   55 WDITScrqqwTRQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGTflGEVYVNGRAlrreqfqdcfSYVLQ 134
Cdd:PLN03232  624 WDSKT-----SKPTLSDINLEIPVGSLVAIVGGTGEGKTSLISAMLGELSHAET--SSVVIRGSV----------AYVPQ 686
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  135 SDTLLSSlTVRETLHYTAllairRGNPGSFQKKVEAVmaelSLSHVADRLIGN--YSLG----GISTGERRRVSIAAQLL 208
Cdd:PLN03232  687 VSWIFNA-TVRENILFGS-----DFESERYWRAIDVT----ALQHDLDLLPGRdlTEIGergvNISGGQKQRVSMARAVY 756
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 530367936  209 QDPKVMLFDEPTTGLDCMTANQIVVLLVELARRNRIVVLTIHQprSELFQLFDKIAILSFGELIFCGTPAEM 280
Cdd:PLN03232  757 SNSDIYIFDDPLSALDAHVAHQVFDSCMKDELKGKTRVLVTNQ--LHFLPLMDRIILVSEGMIKEEGTFAEL 826
ABCC_NFT1 cd03369
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ...
67-277 5.28e-11

ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.


Pssm-ID: 213269 [Multi-domain]  Cd Length: 207  Bit Score: 62.43  E-value: 5.28e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  67 QILKDVSLYVESGQIMCILGSSGSGKTTL-------LDAMSGRLGRAGTFLGEVYVngRALRREqfqdcFSYVLQSDTLL 139
Cdd:cd03369   22 PVLKNVSFKVKAGEKIGIVGRTGAGKSTLilalfrfLEAEEGKIEIDGIDISTIPL--EDLRSS-----LTIIPQDPTLF 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 140 SSlTVRETL----HYTAllairrgnpgsfqkkvEAVMAELSLSHVADRLignyslggiSTGERRRVSIAAQLLQDPKVML 215
Cdd:cd03369   95 SG-TIRSNLdpfdEYSD----------------EEIYGALRVSEGGLNL---------SQGQRQLLCLARALLKRPRVLV 148
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 530367936 216 FDEPTTGLDCMTANQIVVLLVELArrNRIVVLTI-HQPRSELfqLFDKIAILSFGELIFCGTP 277
Cdd:cd03369  149 LDEATASIDYATDALIQKTIREEF--TNSTILTIaHRLRTII--DYDKILVMDAGEVKEYDHP 207
cbiO PRK13634
cobalt transporter ATP-binding subunit; Provisional
66-280 5.41e-11

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237454 [Multi-domain]  Cd Length: 290  Bit Score: 63.50  E-value: 5.41e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  66 RQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLG-RAGTF-LGE-VYVNG------RALRRE-----QFQD--CF 129
Cdd:PRK13634  20 RRALYDVNVSIPSGSYVAIIGHTGSGKSTLLQHLNGLLQpTSGTVtIGErVITAGkknkklKPLRKKvgivfQFPEhqLF 99
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 130 SYVLQSDtllssltvretlhytallaIRRGnPGSF-------QKKVEAVMAELSLSH-VADRlignySLGGISTGERRRV 201
Cdd:PRK13634 100 EETVEKD-------------------ICFG-PMNFgvseedaKQKAREMIELVGLPEeLLAR-----SPFELSGGQMRRV 154
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 202 SIAAQLLQDPKVMLFDEPTTGLDCMTANQIVVLLVELAR-RNRIVVLTIHQpRSELFQLFDKIAILSFGELIFCGTPAEM 280
Cdd:PRK13634 155 AIAGVLAMEPEVLVLDEPTAGLDPKGRKEMMEMFYKLHKeKGLTTVLVTHS-MEDAARYADQIVVMHKGTVFLQGTPREI 233
cbiO PRK13640
energy-coupling factor transporter ATPase;
66-280 5.60e-11

energy-coupling factor transporter ATPase;


Pssm-ID: 184200 [Multi-domain]  Cd Length: 282  Bit Score: 63.67  E-value: 5.60e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  66 RQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGTFLGEVYVNGRALRRE---QFQDCFSYVLQS-DTLLSS 141
Cdd:PRK13640  20 KPALNDISFSIPRGSWTALIGHNGSGKSTISKLINGLLLPDDNPNSKITVDGITLTAKtvwDIREKVGIVFQNpDNQFVG 99
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 142 LTVRETLhytALLAIRRGNPGS-FQKKVEAVMAELSLSHVADRLIGNyslggISTGERRRVSIAAQLLQDPKVMLFDEPT 220
Cdd:PRK13640 100 ATVGDDV---AFGLENRAVPRPeMIKIVRDVLADVGMLDYIDSEPAN-----LSGGQKQRVAIAGILAVEPKIIILDEST 171
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 221 TGLDCMTANQIVVLLVELARRNRIVVLTIHQPRSELfQLFDKIAILSFGELIFCGTPAEM 280
Cdd:PRK13640 172 SMLDPAGKEQILKLIRKLKKKNNLTVISITHDIDEA-NMADQVLVLDDGKLLAQGSPVEI 230
cbiO PRK13641
energy-coupling factor transporter ATPase;
69-280 6.94e-11

energy-coupling factor transporter ATPase;


Pssm-ID: 237456 [Multi-domain]  Cd Length: 287  Bit Score: 63.31  E-value: 6.94e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  69 LKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGtflGEVYVNG------------RALRREqfqdcFSYVLQ-S 135
Cdd:PRK13641  23 LDNISFELEEGSFVALVGHTGSGKSTLMQHFNALLKPSS---GTITIAGyhitpetgnknlKKLRKK-----VSLVFQfP 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 136 DTLLSSLTVRETLHYTALlairrgNPG-SFQKKVEAVMAELSLSHVADRLIgNYSLGGISTGERRRVSIAAQLLQDPKVM 214
Cdd:PRK13641  95 EAQLFENTVLKDVEFGPK------NFGfSEDEAKEKALKWLKKVGLSEDLI-SKSPFELSGGQMRRVAIAGVMAYEPEIL 167
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 530367936 215 LFDEPTTGLDCMTANQIVVLLVELARRNRIVVLTIHQpRSELFQLFDKIAILSFGELIFCGTPAEM 280
Cdd:PRK13641 168 CLDEPAAGLDPEGRKEMMQLFKDYQKAGHTVILVTHN-MDDVAEYADDVLVLEHGKLIKHASPKEI 232
ABC_RNaseL_inhibitor_domain1 cd03236
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
76-250 1.10e-10

The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213203 [Multi-domain]  Cd Length: 255  Bit Score: 62.38  E-value: 1.10e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  76 VESGQIMCILGSSGSGKTTLLDAMSGRL-GRAGTFLGEVYVNG--RALRREQFQDCFSYVLQSDtllssLTVRETLHYTA 152
Cdd:cd03236   23 PREGQVLGLVGPNGIGKSTALKILAGKLkPNLGKFDDPPDWDEilDEFRGSELQNYFTKLLEGD-----VKVIVKPQYVD 97
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 153 LL-AIRRGNPGSFQKKV------EAVMAELSLSHVADRLIGNyslggISTGERRRVSIAAQLLQDPKVMLFDEPTTGLDC 225
Cdd:cd03236   98 LIpKAVKGKVGELLKKKdergklDELVDQLELRHVLDRNIDQ-----LSGGELQRVAIAAALARDADFYFFDEPSSYLDI 172
                        170       180
                 ....*....|....*....|....*...
gi 530367936 226 ---MTANQIVvllVELARRNRIVVLTIH 250
Cdd:cd03236  173 kqrLNAARLI---RELAEDDNYVLVVEH 197
cbiO PRK13649
energy-coupling factor transporter ATPase;
69-280 1.16e-10

energy-coupling factor transporter ATPase;


Pssm-ID: 184208 [Multi-domain]  Cd Length: 280  Bit Score: 62.45  E-value: 1.16e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  69 LKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGtflGEVYVNGRALRREQFQDCFSYVLQSDTLLSSLTVRETL 148
Cdd:PRK13649  23 LFDVNLTIEDGSYTAFIGHTGSGKSTIMQLLNGLHVPTQ---GSVRVDDTLITSTSKNKDIKQIRKKVGLVFQFPESQLF 99
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 149 HYTALLAIRRG--NPGSFQKKVEAVMAE-LSLSHVADRLIGN--YSLGGistGERRRVSIAAQLLQDPKVMLFDEPTTGL 223
Cdd:PRK13649 100 EETVLKDVAFGpqNFGVSQEEAEALAREkLALVGISESLFEKnpFELSG---GQMRRVAIAGILAMEPKILVLDEPTAGL 176
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 530367936 224 DCMTANQIVVLLVELARRNRIVVLTIHqprselfqLFDKIA-------ILSFGELIFCGTPAEM 280
Cdd:PRK13649 177 DPKGRKELMTLFKKLHQSGMTIVLVTH--------LMDDVAnyadfvyVLEKGKLVLSGKPKDI 232
NupO COG3845
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ...
69-280 1.27e-10

ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];


Pssm-ID: 443055 [Multi-domain]  Cd Length: 504  Bit Score: 63.89  E-value: 1.27e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  69 LKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGtflGEVYVNGRALRR---EQFQDC-FSYVL---QSDTLLSS 141
Cdd:COG3845  274 LKDVSLEVRAGEILGIAGVAGNGQSELAEALAGLRPPAS---GSIRLDGEDITGlspRERRRLgVAYIPedrLGRGLVPD 350
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 142 LTVRE----TLHYTALLAiRRG--NPGSFQKKVEAVMAELSL-SHVADRLIGNYSLGGIstgerRRVSIAAQLLQDPKVM 214
Cdd:COG3845  351 MSVAEnlilGRYRRPPFS-RGGflDRKAIRAFAEELIEEFDVrTPGPDTPARSLSGGNQ-----QKVILARELSRDPKLL 424
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 530367936 215 LFDEPTTGLDCMTANQIVVLLVELARRNRIVVLtIHQPRSELFQLFDKIAILSFGELIFCGTPAEM 280
Cdd:COG3845  425 IAAQPTRGLDVGAIEFIHQRLLELRDAGAAVLL-ISEDLDEILALSDRIAVMYEGRIVGEVPAAEA 489
PRK10247 PRK10247
putative ABC transporter ATP-binding protein YbbL; Provisional
65-267 1.33e-10

putative ABC transporter ATP-binding protein YbbL; Provisional


Pssm-ID: 182331 [Multi-domain]  Cd Length: 225  Bit Score: 61.27  E-value: 1.33e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  65 TRQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAgtfLGEVYVNGR---ALRREQFQDCFSYVLQSDTLLSS 141
Cdd:PRK10247  19 DAKILNNISFSLRAGEFKLITGPSGCGKSTLLKIVASLISPT---SGTLLFEGEdisTLKPEIYRQQVSYCAQTPTLFGD 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 142 lTVRETLHYTALlaIRRGNPGsfQKKVEAVMAELSLshvaDRLIGNYSLGGISTGERRRVSIAAQLLQDPKVMLFDEPTT 221
Cdd:PRK10247  96 -TVYDNLIFPWQ--IRNQQPD--PAIFLDDLERFAL----PDTILTKNIAELSGGEKQRISLIRNLQFMPKVLLLDEITS 166
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 530367936 222 GLDcmTANQIVV--LLVELARRNRIVVLTIHQPRSELFQLfDKIAILS 267
Cdd:PRK10247 167 ALD--ESNKHNVneIIHRYVREQNIAVLWVTHDKDEINHA-DKVITLQ 211
cbiO PRK13644
energy-coupling factor transporter ATPase;
69-281 1.39e-10

energy-coupling factor transporter ATPase;


Pssm-ID: 106587 [Multi-domain]  Cd Length: 274  Bit Score: 62.31  E-value: 1.39e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  69 LKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLG-RAGTFLGEVYVNGRALRREQFQDCFSYVLQS-DTLLSSLTVRE 146
Cdd:PRK13644  18 LENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLRpQKGKVLVSGIDTGDFSKLQGIRKLVGIVFQNpETQFVGRTVEE 97
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 147 TLHYTAL-LAIrrgNPGSFQKKVEAVMAELSLSHVADRlignySLGGISTGERRRVSIAAQLLQDPKVMLFDEPTTGLDC 225
Cdd:PRK13644  98 DLAFGPEnLCL---PPIEIRKRVDRALAEIGLEKYRHR-----SPKTLSGGQGQCVALAGILTMEPECLIFDEVTSMLDP 169
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 530367936 226 MTANQIVVLLVELARRNRIVVLTIHQprSELFQLFDKIAILSFGELIFCGTPAEML 281
Cdd:PRK13644 170 DSGIAVLERIKKLHEKGKTIVYITHN--LEELHDADRIIVMDRGKIVLEGEPENVL 223
cbiO PRK13647
cobalt transporter ATP-binding subunit; Provisional
67-282 2.03e-10

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 237457 [Multi-domain]  Cd Length: 274  Bit Score: 61.68  E-value: 2.03e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  67 QILKDVSLYVESGQIMCILGSSGSGKTTLLdamsgrLGRAGTFL---GEVYVNGRALRREQ-----------FQDcfsyv 132
Cdd:PRK13647  19 KALKGLSLSIPEGSKTALLGPNGAGKSTLL------LHLNGIYLpqrGRVKVMGREVNAENekwvrskvglvFQD----- 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 133 lqSDTLLSSLTVRETLhytALLAIRRG-NPGSFQKKVEAVMAELSLSHVADRliGNYSLggiSTGERRRVSIAAQLLQDP 211
Cdd:PRK13647  88 --PDDQVFSSTVWDDV---AFGPVNMGlDKDEVERRVEEALKAVRMWDFRDK--PPYHL---SYGQKKRVAIAGVLAMDP 157
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 530367936 212 KVMLFDEPTTGLDCMTANQIVVLLVELARRNRIVVLTIHQPRSELfQLFDKIAILSFGELIFCGTPAEMLD 282
Cdd:PRK13647 158 DVIVLDEPMAYLDPRGQETLMEILDRLHNQGKTVIVATHDVDLAA-EWADQVIVLKEGRVLAEGDKSLLTD 227
ABC_RNaseL_inhibitor_domain2 cd03237
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ...
69-224 2.07e-10

The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213204 [Multi-domain]  Cd Length: 246  Bit Score: 61.27  E-value: 2.07e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  69 LKDVSLYVESG-----QIMCILGSSGSGKTTLLDAMSGRL----GRAGTFLGEVyvngralrreqfqdcfSYVLQSDTLL 139
Cdd:cd03237   10 LGEFTLEVEGGsisesEVIGILGPNGIGKTTFIKMLAGVLkpdeGDIEIELDTV----------------SYKPQYIKAD 73
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 140 SSLTVRETLHytallAIRRGNPGSFQKKVEaVMAELSLSHVADRLIGNyslggISTGERRRVSIAAQLLQDPKVMLFDEP 219
Cdd:cd03237   74 YEGTVRDLLS-----SITKDFYTHPYFKTE-IAKPLQIEQILDREVPE-----LSGGELQRVAIAACLSKDADIYLLDEP 142

                 ....*
gi 530367936 220 TTGLD 224
Cdd:cd03237  143 SAYLD 147
livG PRK11300
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
72-279 2.54e-10

leucine/isoleucine/valine transporter ATP-binding subunit; Provisional


Pssm-ID: 183080 [Multi-domain]  Cd Length: 255  Bit Score: 61.16  E-value: 2.54e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  72 VSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGtflGEVYVNGRALR--------REQFQDCFSYV--LQSDTLLSS 141
Cdd:PRK11300  24 VNLEVREQEIVSLIGPNGAGKTTVFNCLTGFYKPTG---GTILLRGQHIEglpghqiaRMGVVRTFQHVrlFREMTVIEN 100
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 142 LTVRETLHY-TALLAIRRGNPGSFQKKVEAV-MAELSLSHVADRLIGNYSLGGISTGERRRVSIAAQLLQDPKVMLFDEP 219
Cdd:PRK11300 101 LLVAQHQQLkTGLFSGLLKTPAFRRAESEALdRAATWLERVGLLEHANRQAGNLAYGQQRRLEIARCMVTQPEILMLDEP 180
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 220 TTGLDCMTANQIVVLLVELARRNRIVVLTIHQPRSELFQLFDKIAILSFGELIFCGTPAE 279
Cdd:PRK11300 181 AAGLNPKETKELDELIAELRNEHNVTVLLIEHDMKLVMGISDRIYVVNQGTPLANGTPEE 240
PRK13549 PRK13549
xylose transporter ATP-binding subunit; Provisional
69-282 2.57e-10

xylose transporter ATP-binding subunit; Provisional


Pssm-ID: 184134 [Multi-domain]  Cd Length: 506  Bit Score: 63.02  E-value: 2.57e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  69 LKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGrLGRAGTFLGEVYVNGRALR----REQFQDCFSYVLQSDTLLSSLTV 144
Cdd:PRK13549  21 LDNVSLKVRAGEIVSLCGENGAGKSTLMKVLSG-VYPHGTYEGEIIFEGEELQasniRDTERAGIAIIHQELALVKELSV 99
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 145 RET------------LHYTALLAirrgnpgsfqkKVEAVMAELSLSHVADRLIGNYSLggistGERRRVSIAAQLLQDPK 212
Cdd:PRK13549 100 LENiflgneitpggiMDYDAMYL-----------RAQKLLAQLKLDINPATPVGNLGL-----GQQQLVEIAKALNKQAR 163
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 530367936 213 VMLFDEPTTGLdcmTANQIVVLL--VELARRNRIVVLTIHQPRSELFQLFDKIAILSFGELIfcGT-PAEMLD 282
Cdd:PRK13549 164 LLILDEPTASL---TESETAVLLdiIRDLKAHGIACIYISHKLNEVKAISDTICVIRDGRHI--GTrPAAGMT 231
PRK13549 PRK13549
xylose transporter ATP-binding subunit; Provisional
34-271 2.78e-10

xylose transporter ATP-binding subunit; Provisional


Pssm-ID: 184134 [Multi-domain]  Cd Length: 506  Bit Score: 62.64  E-value: 2.78e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  34 EPHSLG--ILHA-SYSVSHRVRPwwditscrqqwTRQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGrlGRAGTFL 110
Cdd:PRK13549 251 EPHTIGevILEVrNLTAWDPVNP-----------HIKRVDDVSFSLRRGEILGIAGLVGAGRTELVQCLFG--AYPGRWE 317
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 111 GEVYVNGRALRREQFQDCFSYVL-------QSDTLLSSLTVRETLHYTALLAIRRG---NPGSFQKKVEAVMAELSLSHV 180
Cdd:PRK13549 318 GEIFIDGKPVKIRNPQQAIAQGIamvpedrKRDGIVPVMGVGKNITLAALDRFTGGsriDDAAELKTILESIQRLKVKTA 397
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 181 ADRLignySLGGISTGERRRVSIAAQLLQDPKVMLFDEPTTGLDCMTANQIVVLLVELARRNrIVVLTIHQPRSELFQLF 260
Cdd:PRK13549 398 SPEL----AIARLSGGNQQKAVLAKCLLLNPKILILDEPTRGIDVGAKYEIYKLINQLVQQG-VAIIVISSELPEVLGLS 472
                        250
                 ....*....|.
gi 530367936 261 DKIAILSFGEL 271
Cdd:PRK13549 473 DRVLVMHEGKL 483
PRK13657 PRK13657
glucan ABC transporter ATP-binding protein/ permease;
65-243 3.00e-10

glucan ABC transporter ATP-binding protein/ permease;


Pssm-ID: 184214 [Multi-domain]  Cd Length: 588  Bit Score: 62.67  E-value: 3.00e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  65 TRQILKDVSLYVESGQIMCILGSSGSGKTTLL-------DAMSGRLGRAGTFLGEVyvNGRALRREqfqdcFSYVLQsDT 137
Cdd:PRK13657 347 SRQGVEDVSFEAKPGQTVAIVGPTGAGKSTLInllqrvfDPQSGRILIDGTDIRTV--TRASLRRN-----IAVVFQ-DA 418
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 138 LLSSLTVRETlhytallaIRRGNPGSFQKKV-EAVMAELSLSHVADRLIGNYSLGG-----ISTGERRRVSIAAQLLQDP 211
Cdd:PRK13657 419 GLFNRSIEDN--------IRVGRPDATDEEMrAAAERAQAHDFIERKPDGYDTVVGergrqLSGGERQRLAIARALLKDP 490
                        170       180       190
                 ....*....|....*....|....*....|..
gi 530367936 212 KVMLFDEPTTGLDCMTANQIVVLLVELaRRNR 243
Cdd:PRK13657 491 PILILDEATSALDVETEAKVKAALDEL-MKGR 521
ABC_ABC_ChvD TIGR03719
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ...
66-224 3.71e-10

ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.


Pssm-ID: 274744 [Multi-domain]  Cd Length: 552  Bit Score: 62.26  E-value: 3.71e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936   66 RQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGrlgragtfLGEVYvNGRALRREQFQdcFSYVLQSDTLLSSLTVR 145
Cdd:TIGR03719  18 KEILKDISLSFFPGAKIGVLGLNGAGKSTLLRIMAG--------VDKDF-NGEARPQPGIK--VGYLPQEPQLDPTKTVR 86
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  146 ETL--------------------------HYTALLAirrgNPGSFQKKVEAVMA---ELSLSHVADRL---IGNYSLGGI 193
Cdd:TIGR03719  87 ENVeegvaeikdaldrfneisakyaepdaDFDKLAA----EQAELQEIIDAADAwdlDSQLEIAMDALrcpPWDADVTKL 162
                         170       180       190
                  ....*....|....*....|....*....|.
gi 530367936  194 STGERRRVSIAAQLLQDPKVMLFDEPTTGLD 224
Cdd:TIGR03719 163 SGGERRRVALCRLLLSKPDMLLLDEPTNHLD 193
PstB COG1117
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ...
65-280 5.04e-10

ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];


Pssm-ID: 440734 [Multi-domain]  Cd Length: 258  Bit Score: 60.05  E-value: 5.04e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  65 TRQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSgRL------GRAGtflGEVYVNGR----------ALRREqfqdc 128
Cdd:COG1117   23 DKQALKDINLDIPENKVTALIGPSGCGKSTLLRCLN-RMndlipgARVE---GEILLDGEdiydpdvdvvELRRR----- 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 129 FSYVLQSDTLLsSLTVRETLHYTA-LLAIRRgnpgsfqKKVEAVMAELSLSHVA------DRLigNYSLGGISTGERRRV 201
Cdd:COG1117   94 VGMVFQKPNPF-PKSIYDNVAYGLrLHGIKS-------KSELDEIVEESLRKAAlwdevkDRL--KKSALGLSGGQQQRL 163
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 202 SIAAQLLQDPKVMLFDEPTTGLDCMTANQIVVLLVELARRNRIVVLT--IHQPRselfQLFDKIAILSFGELIFCGTPAE 279
Cdd:COG1117  164 CIARALAVEPEVLLMDEPTSALDPISTAKIEELILELKKDYTIVIVThnMQQAA----RVSDYTAFFYLGELVEFGPTEQ 239

                 .
gi 530367936 280 M 280
Cdd:COG1117  240 I 240
PRK09700 PRK09700
D-allose ABC transporter ATP-binding protein AlsA;
67-275 6.20e-10

D-allose ABC transporter ATP-binding protein AlsA;


Pssm-ID: 182036 [Multi-domain]  Cd Length: 510  Bit Score: 61.72  E-value: 6.20e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  67 QILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGtflGEVYVNGRALRR----EQFQDCFSYVLQSDTLLSSL 142
Cdd:PRK09700  19 HALKSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPTK---GTITINNINYNKldhkLAAQLGIGIIYQELSVIDEL 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 143 TVRETLhYTALLAIRR--GNP----GSFQKKVEAVMAELSLSHVADRLIGNYSlggIStgERRRVSIAAQLLQDPKVMLF 216
Cdd:PRK09700  96 TVLENL-YIGRHLTKKvcGVNiidwREMRVRAAMMLLRVGLKVDLDEKVANLS---IS--HKQMLEIAKTLMLDAKVIIM 169
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 530367936 217 DEPTTGLDCMTANQIVVLLVELARRNRIVVLTIHQpRSELFQLFDKIAILSFGELIFCG 275
Cdd:PRK09700 170 DEPTSSLTNKEVDYLFLIMNQLRKEGTAIVYISHK-LAEIRRICDRYTVMKDGSSVCSG 227
PRK14258 PRK14258
phosphate ABC transporter ATP-binding protein; Provisional
65-270 6.22e-10

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 184593 [Multi-domain]  Cd Length: 261  Bit Score: 60.05  E-value: 6.22e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  65 TRQILKDVSLYVESGQIMCILGSSGSGKTTLLDAmsgrLGRAGTFLGEVYVNGRA----------------LRREqfqdc 128
Cdd:PRK14258  19 TQKILEGVSMEIYQSKVTAIIGPSGCGKSTFLKC----LNRMNELESEVRVEGRVeffnqniyerrvnlnrLRRQ----- 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 129 FSYVLQSDTLLSsLTVRETLHYTALLAIRRGNPgSFQKKVEAVMAELSL-SHVADRLigNYSLGGISTGERRRVSIAAQL 207
Cdd:PRK14258  90 VSMVHPKPNLFP-MSVYDNVAYGVKIVGWRPKL-EIDDIVESALKDADLwDEIKHKI--HKSALDLSGGQQQRLCIARAL 165
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 530367936 208 LQDPKVMLFDEPTTGLDCMTANQIVVLLVELARRNRIVVLTIHQPRSELFQLFDKIAILSFGE 270
Cdd:PRK14258 166 AVKPKVLLMDEPCFGLDPIASMKVESLIQSLRLRSELTMVIVSHNLHQVSRLSDFTAFFKGNE 228
ABCF_EF-3 cd03221
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ...
66-250 6.72e-10

ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.


Pssm-ID: 213188 [Multi-domain]  Cd Length: 144  Bit Score: 57.46  E-value: 6.72e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  66 RQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLgraGTFLGEVYVNGRALrreqfqdcFSYVLQsdtlLSSltvr 145
Cdd:cd03221   13 KLLLKDISLTINPGDRIGLVGRNGAGKSTLLKLIAGEL---EPDEGIVTWGSTVK--------IGYFEQ----LSG---- 73
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 146 etlhytallairrgnpgsfqkkveavmaelslshvadrlignyslggistGERRRVSIAAQLLQDPKVMLFDEPTTGLDc 225
Cdd:cd03221   74 --------------------------------------------------GEKMRLALAKLLLENPNLLLLDEPTNHLD- 102
                        170       180
                 ....*....|....*....|....*
gi 530367936 226 MTAnqIVVLLVELARRNRIVVLTIH 250
Cdd:cd03221  103 LES--IEALEEALKEYPGTVILVSH 125
MRP_assoc_pro TIGR00957
multi drug resistance-associated protein (MRP); This model describes multi drug ...
31-281 6.98e-10

multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]


Pssm-ID: 188098 [Multi-domain]  Cd Length: 1522  Bit Score: 62.27  E-value: 6.98e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936    31 TAPE---PHSLGILHASYSVshRVRPWWDItscrqqwtrqILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSgRLGRAG 107
Cdd:TIGR00957 1273 TAPPsgwPPRGRVEFRNYCL--RYREDLDL----------VLRHINVTIHGGEKVGIVGRTGAGKSSLTLGLF-RINESA 1339
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936   108 TflGEVYVNGRALRREQFQDCFS--YVLQSDTLLSSLTVRETLhytallairrgNPGSfQKKVEAVMAELSLSHV----- 180
Cdd:TIGR00957 1340 E--GEIIIDGLNIAKIGLHDLRFkiTIIPQDPVLFSGSLRMNL-----------DPFS-QYSDEEVWWALELAHLktfvs 1405
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936   181 --ADRLIGNYSLGG--ISTGERRRVSIAAQLLQDPKVMLFDEPTTGLDCMTANqivvlLVELARRNRI---VVLTIHQpR 253
Cdd:TIGR00957 1406 alPDKLDHECAEGGenLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDN-----LIQSTIRTQFedcTVLTIAH-R 1479
                          250       260
                   ....*....|....*....|....*...
gi 530367936   254 SELFQLFDKIAILSFGELIFCGTPAEML 281
Cdd:TIGR00957 1480 LNTIMDYTRVIVLDKGEVAEFGAPSNLL 1507
PRK10908 PRK10908
cell division ATP-binding protein FtsE;
66-250 8.48e-10

cell division ATP-binding protein FtsE;


Pssm-ID: 182829 [Multi-domain]  Cd Length: 222  Bit Score: 59.12  E-value: 8.48e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  66 RQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGrLGRAGTflGEVYVNGRALRREQFQDC------FSYVLQSDTLL 139
Cdd:PRK10908  15 RQALQGVTFHMRPGEMAFLTGHSGAGKSTLLKLICG-IERPSA--GKIWFSGHDITRLKNREVpflrrqIGMIFQDHHLL 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 140 SSLTVRETLHYTALLAIRRGNpgSFQKKVEAVMAELSLSHVADrligNYSLGgISTGERRRVSIAAQLLQDPKVMLFDEP 219
Cdd:PRK10908  92 MDRTVYDNVAIPLIIAGASGD--DIRRRVSAALDKVGLLDKAK----NFPIQ-LSGGEQQRVGIARAVVNKPAVLLADEP 164
                        170       180       190
                 ....*....|....*....|....*....|.
gi 530367936 220 TTGLDCMTANQIVVLLVELARRNRIVVLTIH 250
Cdd:PRK10908 165 TGNLDDALSEGILRLFEEFNRVGVTVLMATH 195
PRK10762 PRK10762
D-ribose transporter ATP binding protein; Provisional
69-224 9.70e-10

D-ribose transporter ATP binding protein; Provisional


Pssm-ID: 236755 [Multi-domain]  Cd Length: 501  Bit Score: 61.17  E-value: 9.70e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  69 LKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGtflGEVYVNGRALRREQFQDCFSYVL-------QSDTLLSS 141
Cdd:PRK10762 268 VNDVSFTLRKGEILGVSGLMGAGRTELMKVLYGALPRTS---GYVTLDGHEVVTRSPQDGLANGIvyisedrKRDGLVLG 344
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 142 LTVRETLHYTALLAIRRGNpGSFQKKVE--AVMAELSLSHV----ADRLIGNyslggISTGERRRVSIAAQLLQDPKVML 215
Cdd:PRK10762 345 MSVKENMSLTALRYFSRAG-GSLKHADEqqAVSDFIRLFNIktpsMEQAIGL-----LSGGNQQKVAIARGLMTRPKVLI 418

                 ....*....
gi 530367936 216 FDEPTTGLD 224
Cdd:PRK10762 419 LDEPTRGVD 427
dppF PRK11308
dipeptide transporter ATP-binding subunit; Provisional
61-238 1.01e-09

dipeptide transporter ATP-binding subunit; Provisional


Pssm-ID: 236898 [Multi-domain]  Cd Length: 327  Bit Score: 59.98  E-value: 1.01e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  61 RQQWTRQILKDVSLYVESGQIMCILGSSGSGKTTLldamsgrlGRAGTFL-----GEVYVNG----------RALRREQF 125
Cdd:PRK11308  23 KPERLVKALDGVSFTLERGKTLAVVGESGCGKSTL--------ARLLTMIetptgGELYYQGqdllkadpeaQKLLRQKI 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 126 QdcfsYVLQSDtlLSSLTVRETLHY---------TALLAIRRgnpgsfQKKVEAVMAELSL--SHvADRLIGNYSlggis 194
Cdd:PRK11308  95 Q----IVFQNP--YGSLNPRKKVGQileepllinTSLSAAER------REKALAMMAKVGLrpEH-YDRYPHMFS----- 156
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 530367936 195 TGERRRVSIAAQLLQDPKVMLFDEPTTGLDCMTANQIVVLLVEL 238
Cdd:PRK11308 157 GGQRQRIAIARALMLDPDVVVADEPVSALDVSVQAQVLNLMMDL 200
ssuB PRK11247
aliphatic sulfonates transport ATP-binding subunit; Provisional
66-271 1.05e-09

aliphatic sulfonates transport ATP-binding subunit; Provisional


Pssm-ID: 183055 [Multi-domain]  Cd Length: 257  Bit Score: 59.31  E-value: 1.05e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  66 RQILKDVSLYVESGQIMCILGSSGSGKTTLL-------DAMSGRLGRAGTFLGEVyvngRALRREQFQDCfsyvlqsdTL 138
Cdd:PRK11247  25 RTVLNQLDLHIPAGQFVAVVGRSGCGKSTLLrllagleTPSAGELLAGTAPLAEA----REDTRLMFQDA--------RL 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 139 LSSLTVRETLHytalLAIRrgnpGSFQKKVEAVMAELSLshvADRliGNYSLGGISTGERRRVSIAAQLLQDPKVMLFDE 218
Cdd:PRK11247  93 LPWKKVIDNVG----LGLK----GQWRDAALQALAAVGL---ADR--ANEWPAALSGGQKQRVALARALIHRPGLLLLDE 159
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 530367936 219 PTTGLDCMTANQIVVLLVELARRNRIVVLTIHQPRSELFQLFDKIAILSFGEL 271
Cdd:PRK11247 160 PLGALDALTRIEMQDLIESLWQQHGFTVLLVTHDVSEAVAMADRVLLIEEGKI 212
YddA COG4178
ABC-type uncharacterized transport system, permease and ATPase components [General function ...
66-267 1.18e-09

ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];


Pssm-ID: 443337 [Multi-domain]  Cd Length: 571  Bit Score: 60.98  E-value: 1.18e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  66 RQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGrLGRAGTflgevyvnGRALRREQFQDCF----SYvLQSDTLlss 141
Cdd:COG4178  376 RPLLEDLSLSLKPGERLLITGPSGSGKSTLLRAIAG-LWPYGS--------GRIARPAGARVLFlpqrPY-LPLGTL--- 442
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 142 ltvRETLHYTALlairrgnPGSF-QKKVEAVMAELSLSHVADRLIGNYSLGGI-STGERRRVSIAAQLLQDPKVMLFDEP 219
Cdd:COG4178  443 ---REALLYPAT-------AEAFsDAELREALEAVGLGHLAERLDEEADWDQVlSLGEQQRLAFARLLLHKPDWLFLDEA 512
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 530367936 220 TTGLDCMTANQIVVLLVElaRRNRIVVLTI-HqpRSELFQLFDKIAILS 267
Cdd:COG4178  513 TSALDEENEAALYQLLRE--ELPGTTVISVgH--RSTLAAFHDRVLELT 557
PRK15134 PRK15134
microcin C ABC transporter ATP-binding protein YejF; Provisional
67-249 1.43e-09

microcin C ABC transporter ATP-binding protein YejF; Provisional


Pssm-ID: 237917 [Multi-domain]  Cd Length: 529  Bit Score: 60.49  E-value: 1.43e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  67 QILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSgRLGRAGtflGEVYVNGRAL------------RREQ--FQDCFSyv 132
Cdd:PRK15134 300 VVVKNISFTLRPGETLGLVGESGSGKSTTGLALL-RLINSQ---GEIWFDGQPLhnlnrrqllpvrHRIQvvFQDPNS-- 373
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 133 lqsdTLLSSLTVRE------TLHYTALLAIRRgnpgsfQKKVEAVMAELSLSHVA-DRLIGNYSlggisTGERRRVSIAA 205
Cdd:PRK15134 374 ----SLNPRLNVLQiieeglRVHQPTLSAAQR------EQQVIAVMEEVGLDPETrHRYPAEFS-----GGQRQRIAIAR 438
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 530367936 206 QLLQDPKVMLFDEPTTGLDCMTANQIVVLLVELARRNRIVVLTI 249
Cdd:PRK15134 439 ALILKPSLIILDEPTSSLDKTVQAQILALLKSLQQKHQLAYLFI 482
dppD PRK11022
dipeptide transporter ATP-binding subunit; Provisional
72-250 1.94e-09

dipeptide transporter ATP-binding subunit; Provisional


Pssm-ID: 182906 [Multi-domain]  Cd Length: 326  Bit Score: 59.37  E-value: 1.94e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  72 VSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGTFLGE-VYVNGRAL-------RREQFQDCFSYVLQSDtlLSSLT 143
Cdd:PRK11022  26 ISYSVKQGEVVGIVGESGSGKSVSSLAIMGLIDYPGRVMAEkLEFNGQDLqrisekeRRNLVGAEVAMIFQDP--MTSLN 103
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 144 VRETLHYTALLAIRRGNPGSFQKKVEAVMAELSLSHVAD---RL-IGNYSLGGistGERRRVSIAAQLLQDPKVMLFDEP 219
Cdd:PRK11022 104 PCYTVGFQIMEAIKVHQGGNKKTRRQRAIDLLNQVGIPDpasRLdVYPHQLSG---GMSQRVMIAMAIACRPKLLIADEP 180
                        170       180       190
                 ....*....|....*....|....*....|..
gi 530367936 220 TTGLDCMTANQIVVLLVELARR-NRIVVLTIH 250
Cdd:PRK11022 181 TTALDVTIQAQIIELLLELQQKeNMALVLITH 212
PRK11176 PRK11176
lipid A ABC transporter ATP-binding protein/permease MsbA;
69-281 2.20e-09

lipid A ABC transporter ATP-binding protein/permease MsbA;


Pssm-ID: 183016 [Multi-domain]  Cd Length: 582  Bit Score: 60.03  E-value: 2.20e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  69 LKDVSLYVESGQIMCILGSSGSGKTT---LL----DAMSGrlgragtflgEVYVNGRALR-------REQFqdcfSYVLQ 134
Cdd:PRK11176 359 LRNINFKIPAGKTVALVGRSGSGKSTianLLtrfyDIDEG----------EILLDGHDLRdytlaslRNQV----ALVSQ 424
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 135 S-----DTLLSSLTVRETLHYT---ALLAIRRGNPGSFQKKVEavmaelslsHVADRLIG-NYSLggISTGERRRVSIAA 205
Cdd:PRK11176 425 NvhlfnDTIANNIAYARTEQYSreqIEEAARMAYAMDFINKMD---------NGLDTVIGeNGVL--LSGGQRQRIAIAR 493
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 530367936 206 QLLQDPKVMLFDEPTTGLDCMTANQIVVLLVELaRRNRIVVLTIHqpRSELFQLFDKIAILSFGELIFCGTPAEML 281
Cdd:PRK11176 494 ALLRDSPILILDEATSALDTESERAIQAALDEL-QKNRTSLVIAH--RLSTIEKADEILVVEDGEIVERGTHAELL 566
PRK13651 PRK13651
cobalt transporter ATP-binding subunit; Provisional
67-250 2.37e-09

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184210 [Multi-domain]  Cd Length: 305  Bit Score: 58.94  E-value: 2.37e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  67 QILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRL----GRAGTFLGEVYVNGRALRREQFQDcfSYVLQSDTLLSSL 142
Cdd:PRK13651  21 KALDNVSVEINQGEFIAIIGQTGSGKTTFIEHLNALLlpdtGTIEWIFKDEKNKKKTKEKEKVLE--KLVIQKTRFKKIK 98
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 143 TVREtlhytallaIRRGNPGSFQkkveavMAELSLSHVA---DRLIGNYSLG---------------------------- 191
Cdd:PRK13651  99 KIKE---------IRRRVGVVFQ------FAEYQLFEQTiekDIIFGPVSMGvskeeakkraakyielvgldesylqrsp 163
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 192 -GISTGERRRVSIAAQLLQDPKVMLFDEPTTGLDCMTANQIVVLLVELARRNRIVVLTIH 250
Cdd:PRK13651 164 fELSGGQKRRVALAGILAMEPDFLVFDEPTAGLDPQGVKEILEIFDNLNKQGKTIILVTH 223
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
77-250 2.40e-09

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 59.80  E-value: 2.40e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  77 ESGQIMCILGSSGSGKTTLLDAMSGR----LGR--------------AGTFLGEvY----VNG--RALRREQFQDCFSYV 132
Cdd:COG1245   97 KKGKVTGILGPNGIGKSTALKILSGElkpnLGDydeepswdevlkrfRGTELQD-YfkklANGeiKVAHKPQYVDLIPKV 175
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 133 LqsdtllsSLTVRETLHYTAllaiRRGnpgsfqkKVEAVMAELSLSHVADRLIGNyslggISTGERRRVSIAAQLLQDPK 212
Cdd:COG1245  176 F-------KGTVRELLEKVD----ERG-------KLDELAEKLGLENILDRDISE-----LSGGELQRVAIAAALLRDAD 232
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 530367936 213 VMLFDEPTTGLDC---MTANQIVvllVELARRNRIVVLTIH 250
Cdd:COG1245  233 FYFFDEPSSYLDIyqrLNVARLI---RELAEEGKYVLVVEH 270
PLN03130 PLN03130
ABC transporter C family member; Provisional
55-246 2.49e-09

ABC transporter C family member; Provisional


Pssm-ID: 215595 [Multi-domain]  Cd Length: 1622  Bit Score: 60.52  E-value: 2.49e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936   55 WDITScrqqwTRQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLgrAGTFLGEVYVNGRAlrreqfqdcfSYVLQ 134
Cdd:PLN03130  624 WDSKA-----ERPTLSNINLDVPVGSLVAIVGSTGEGKTSLISAMLGEL--PPRSDASVVIRGTV----------AYVPQ 686
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  135 SDTLLSSlTVRETLHYTALLairrgNPGSFQKKVEAVmaelSLSHVADRL-------IGNYSLGgISTGERRRVSIAAQL 207
Cdd:PLN03130  687 VSWIFNA-TVRDNILFGSPF-----DPERYERAIDVT----ALQHDLDLLpggdlteIGERGVN-ISGGQKQRVSMARAV 755
                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 530367936  208 LQDPKVMLFDEPTTGLDCMTANQIV--VLLVELARRNRIVV 246
Cdd:PLN03130  756 YSNSDVYIFDDPLSALDAHVGRQVFdkCIKDELRGKTRVLV 796
PRK15439 PRK15439
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
68-282 2.81e-09

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional


Pssm-ID: 185336 [Multi-domain]  Cd Length: 510  Bit Score: 59.68  E-value: 2.81e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  68 ILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGtflGEVYVNGRALRR---EQFQDCFSY-VLQSDTLLSSLT 143
Cdd:PRK15439  26 VLKGIDFTLHAGEVHALLGGNGAGKSTLMKIIAGIVPPDS---GTLEIGGNPCARltpAKAHQLGIYlVPQEPLLFPNLS 102
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 144 VRETlhytalLAIRRGNPGSFQKKVEAVMAELSLShvadrLIGNYSLGGISTGERRRVSIAAQLLQDPKVMLFDEPTTGL 223
Cdd:PRK15439 103 VKEN------ILFGLPKRQASMQKMKQLLAALGCQ-----LDLDSSAGSLEVADRQIVEILRGLMRDSRILILDEPTASL 171
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 530367936 224 DCMTANQIVVLLVELARRNRIVVLTIHQPRsELFQLFDKIAILSFGELIFCGTPAEMLD 282
Cdd:PRK15439 172 TPAETERLFSRIRELLAQGVGIVFISHKLP-EIRQLADRISVMRDGTIALSGKTADLST 229
3a01208 TIGR00958
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
66-282 3.67e-09

Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]


Pssm-ID: 273363 [Multi-domain]  Cd Length: 711  Bit Score: 59.35  E-value: 3.67e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936   66 RQILKDVSLYVESGQIMCILGSSGSGKTTLLdAMSGRLGRAGTflGEVYVNGRALrrEQFQDCFSY----VLQSDTLLSS 141
Cdd:TIGR00958 494 VPVLKGLTFTLHPGEVVALVGPSGSGKSTVA-ALLQNLYQPTG--GQVLLDGVPL--VQYDHHYLHrqvaLVGQEPVLFS 568
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  142 LTVRETLHYtallairrgnpGSFQKKVEAVMAELSLSHvADRLIGNYSLGG----------ISTGERRRVSIAAQLLQDP 211
Cdd:TIGR00958 569 GSVRENIAY-----------GLTDTPDEEIMAAAKAAN-AHDFIMEFPNGYdtevgekgsqLSGGQKQRIAIARALVRKP 636
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 530367936  212 KVMLFDEPTTGLDCmtanQIVVLLVEL-ARRNRIVVLTIHqpRSELFQLFDKIAILSFGELIFCGTPAEMLD 282
Cdd:TIGR00958 637 RVLILDEATSALDA----ECEQLLQESrSRASRTVLLIAH--RLSTVERADQILVLKKGSVVEMGTHKQLME 702
ugpC PRK11650
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;
67-224 7.20e-09

sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;


Pssm-ID: 236947 [Multi-domain]  Cd Length: 356  Bit Score: 57.55  E-value: 7.20e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  67 QILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGrlgragtfL-----GEVYVNGR-------ALRreqfqDCfSYVLQ 134
Cdd:PRK11650  18 QVIKGIDLDVADGEFIVLVGPSGCGKSTLLRMVAG--------LeritsGEIWIGGRvvnelepADR-----DI-AMVFQ 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 135 SDTLLSSLTVRETLHYTalLAIRRGNPGSFQKKVEAVMAELSLSHVADR----LignyslggiSTGERRRVSIAAQLLQD 210
Cdd:PRK11650  84 NYALYPHMSVRENMAYG--LKIRGMPKAEIEERVAEAARILELEPLLDRkpreL---------SGGQRQRVAMGRAIVRE 152
                        170
                 ....*....|....
gi 530367936 211 PKVMLFDEPTTGLD 224
Cdd:PRK11650 153 PAVFLFDEPLSNLD 166
PRK15439 PRK15439
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
70-271 8.15e-09

autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional


Pssm-ID: 185336 [Multi-domain]  Cd Length: 510  Bit Score: 58.14  E-value: 8.15e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  70 KDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGtflGEVYVNGRALRREQFQDCFS----YvLQSDTLLSSLTVR 145
Cdd:PRK15439 280 RNISLEVRAGEILGLAGVVGAGRTELAETLYGLRPARG---GRIMLNGKEINALSTAQRLArglvY-LPEDRQSSGLYLD 355
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 146 ETLHYTAlLAIRRGNPGSFQK-KVEAVMAE-------LSLSHVadrligNYSLGGISTGERRRVSIAAQLLQDPKVMLFD 217
Cdd:PRK15439 356 APLAWNV-CALTHNRRGFWIKpARENAVLEryrralnIKFNHA------EQAARTLSGGNQQKVLIAKCLEASPQLLIVD 428
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 530367936 218 EPTTGLDCMTANQIVVLLVELARRNrIVVLTIHQPRSELFQLFDKIAILSFGEL 271
Cdd:PRK15439 429 EPTRGVDVSARNDIYQLIRSIAAQN-VAVLFISSDLEEIEQMADRVLVMHQGEI 481
PRK14271 PRK14271
phosphate ABC transporter ATP-binding protein; Provisional
66-314 1.09e-08

phosphate ABC transporter ATP-binding protein; Provisional


Pssm-ID: 172759 [Multi-domain]  Cd Length: 276  Bit Score: 56.64  E-value: 1.09e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  66 RQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAG--TFLGEVYVNGRALRreQFQDCFSYVLQSDTLLSSLT 143
Cdd:PRK14271  34 KTVLDQVSMGFPARAVTSLMGPTGSGKTTFLRTLNRMNDKVSgyRYSGDVLLGGRSIF--NYRDVLEFRRRVGMLFQRPN 111
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 144 VRETLHYTALLAIRRGNP----GSFQKKVEAVMAELSL-SHVADRLigNYSLGGISTGERRRVSIAAQLLQDPKVMLFDE 218
Cdd:PRK14271 112 PFPMSIMDNVLAGVRAHKlvprKEFRGVAQARLTEVGLwDAVKDRL--SDSPFRLSGGQQQLLCLARTLAVNPEVLLLDE 189
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 219 PTTGLDCMTANQIVVLLVELArrNRIVVLTIHQPRSELFQLFDKIAILSFGELIFCGtPAEMLdffndcgYPCPEHSNPF 298
Cdd:PRK14271 190 PTSALDPTTTEKIEEFIRSLA--DRLTVIIVTHNLAQAARISDRAALFFDGRLVEEG-PTEQL-------FSSPKHAETA 259
                        250
                 ....*....|....*.
gi 530367936 299 DFYMDLTSvDTQSKER 314
Cdd:PRK14271 260 RYVAGLSG-DVKDAKR 274
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
73-224 1.19e-08

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 57.51  E-value: 1.19e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  73 SLY----VESGQIMCILGSSGSGKTTLLDAMSGR----LGR--------------AGTFLG----EVYVNG-RALRREQF 125
Cdd:PRK13409  89 KLYglpiPKEGKVTGILGPNGIGKTTAVKILSGElipnLGDyeeepswdevlkrfRGTELQnyfkKLYNGEiKVVHKPQY 168
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 126 QDCFSYVLQSdtllsslTVRETLHYTAllaiRRGnpgsfqkKVEAVMAELSLSHVADRLIGNyslggISTGERRRVSIAA 205
Cdd:PRK13409 169 VDLIPKVFKG-------KVRELLKKVD----ERG-------KLDEVVERLGLENILDRDISE-----LSGGELQRVAIAA 225
                        170
                 ....*....|....*....
gi 530367936 206 QLLQDPKVMLFDEPTTGLD 224
Cdd:PRK13409 226 ALLRDADFYFFDEPTSYLD 244
CFTR_protein TIGR01271
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ...
66-251 1.22e-08

cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]


Pssm-ID: 273530 [Multi-domain]  Cd Length: 1490  Bit Score: 58.00  E-value: 1.22e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936    66 RQILKDVSLYVESGQIMCILGSSGSGKTTLLDAmsgrLGRAGTFLGEVYVNG---RALRREQFQDCFSYVLQSDTLLSSl 142
Cdd:TIGR01271 1232 RAVLQDLSFSVEGGQRVGLLGRTGSGKSTLLSA----LLRLLSTEGEIQIDGvswNSVTLQTWRKAFGVIPQKVFIFSG- 1306
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936   143 TVRETLHYTALLAirrgnpgsfQKKVEAVMAELSLSHVADRLIG--NYSL--GG--ISTGERRRVSIAAQLLQDPKVMLF 216
Cdd:TIGR01271 1307 TFRKNLDPYEQWS---------DEEIWKVAEEVGLKSVIEQFPDklDFVLvdGGyvLSNGHKQLMCLARSILSKAKILLL 1377
                          170       180       190
                   ....*....|....*....|....*....|....*
gi 530367936   217 DEPTTGLDCMTAnQIVVLLVELARRNRIVVLTIHQ 251
Cdd:TIGR01271 1378 DEPSAHLDPVTL-QIIRKTLKQSFSNCTVILSEHR 1411
PRK13543 PRK13543
heme ABC exporter ATP-binding protein CcmA;
68-224 1.67e-08

heme ABC exporter ATP-binding protein CcmA;


Pssm-ID: 184129 [Multi-domain]  Cd Length: 214  Bit Score: 55.24  E-value: 1.67e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  68 ILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGrLGRAGTflGEVYVNGRALRREQFQDCFSYVLQSDTLLSSLTVRET 147
Cdd:PRK13543  26 VFGPLDFHVDAGEALLVQGDNGAGKTTLLRVLAG-LLHVES--GQIQIDGKTATRGDRSRFMAYLGHLPGLKADLSTLEN 102
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 530367936 148 LHYTALLAIRRGN--PGSfqkkveaVMAELSLSHVADRLIGNyslggISTGERRRVSIAAQLLQDPKVMLFDEPTTGLD 224
Cdd:PRK13543 103 LHFLCGLHGRRAKqmPGS-------ALAIVGLAGYEDTLVRQ-----LSAGQKKRLALARLWLSPAPLWLLDEPYANLD 169
ABCD_peroxisomal_ALDP cd03223
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ...
66-267 1.71e-08

ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).


Pssm-ID: 213190 [Multi-domain]  Cd Length: 166  Bit Score: 54.08  E-value: 1.71e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  66 RQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGrLGRAGTflGEVyvnGRALRREQFqdcfsYVLQSdTLLSSLTVR 145
Cdd:cd03223   14 RVLLKDLSFEIKPGDRLLITGPSGTGKSSLFRALAG-LWPWGS--GRI---GMPEGEDLL-----FLPQR-PYLPLGTLR 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 146 ETLHYtallairrgnpgsfqkkveAVMAELSLshvadrlignyslggistGERRRVSIAAQLLQDPKVMLFDEPTTGLDC 225
Cdd:cd03223   82 EQLIY-------------------PWDDVLSG------------------GEQQRLAFARLLLHKPKFVFLDEATSALDE 124
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 530367936 226 MTANQIVVLLVELarrnRIVVLTI-HqpRSELFQLFDKIAILS 267
Cdd:cd03223  125 ESEDRLYQLLKEL----GITVISVgH--RPSLWKFHDRVLDLD 161
PTZ00243 PTZ00243
ABC transporter; Provisional
66-279 2.37e-08

ABC transporter; Provisional


Pssm-ID: 240327 [Multi-domain]  Cd Length: 1560  Bit Score: 57.10  E-value: 2.37e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936   66 RQILKDVSLYVESGQIMCILGSSGSGKTTLLdamsgrlgraGTFLGEVYVN-GRALRREQfqdcFSYVLQSDTLLSSlTV 144
Cdd:PTZ00243  673 KVLLRDVSVSVPRGKLTVVLGATGSGKSTLL----------QSLLSQFEISeGRVWAERS----IAYVPQQAWIMNA-TV 737
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  145 RETlhytaLLAIRRGNPGSFQKKVEAVMAELSLSHVADRL---IGNYSLgGISTGERRRVSIAAQLLQDPKVMLFDEPTT 221
Cdd:PTZ00243  738 RGN-----ILFFDEEDAARLADAVRVSQLEADLAQLGGGLeteIGEKGV-NLSGGQKARVSLARAVYANRDVYLLDDPLS 811
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  222 GLDCMTANQIV--VLLVELARRNRivVLTIHQprSELFQLFDKIAILSFGELIFCGTPAE 279
Cdd:PTZ00243  812 ALDAHVGERVVeeCFLGALAGKTR--VLATHQ--VHVVPRADYVVALGDGRVEFSGSSAD 867
cbiO PRK13648
cobalt transporter ATP-binding subunit; Provisional
69-282 2.45e-08

cobalt transporter ATP-binding subunit; Provisional


Pssm-ID: 184207 [Multi-domain]  Cd Length: 269  Bit Score: 55.53  E-value: 2.45e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  69 LKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGrLGRAGTflGEVYVNGRALRREQFQDCFSY---VLQSDtllSSLTVR 145
Cdd:PRK13648  25 LKDVSFNIPKGQWTSIVGHNGSGKSTIAKLMIG-IEKVKS--GEIFYNNQAITDDNFEKLRKHigiVFQNP---DNQFVG 98
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 146 ETLHYTALLAIRrGNPGSFQKKVEAVMAELSLSHVADRliGNYSLGGISTGERRRVSIAAQLLQDPKVMLFDEPTTGLDC 225
Cdd:PRK13648  99 SIVKYDVAFGLE-NHAVPYDEMHRRVSEALKQVDMLER--ADYEPNALSGGQKQRVAIAGVLALNPSVIILDEATSMLDP 175
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 530367936 226 MTANQIVVLLVELARRNRIVVLTIHQPRSELFQLfDKIAILSFGELIFCGTPAEMLD 282
Cdd:PRK13648 176 DARQNLLDLVRKVKSEHNITIISITHDLSEAMEA-DHVIVMNKGTVYKEGTPTEIFD 231
40850658_otr NF000106
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
165-280 2.64e-08

oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;


Pssm-ID: 411078 [Multi-domain]  Cd Length: 351  Bit Score: 55.90  E-value: 2.64e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 165 QKKVEAVMAELSLSHVADRLIGNYSlGGIstgeRRRVSIAAQLLQDPKVMLFDEPTTGLDCMTANQIVVLLVELARRNRI 244
Cdd:NF000106 122 RARADELLERFSLTEAAGRAAAKYS-GGM----RRRLDLAASMIGRPAVLYLDEPTTGLDPRTRNEVWDEVRSMVRDGAT 196
                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 530367936 245 VVLTIhQPRSELFQLFDKIAILSFGELIFCGTPAEM 280
Cdd:NF000106 197 VLLTT-QYMEEAEQLAHELTVIDRGRVIADGKVDEL 231
cbiO PRK13642
energy-coupling factor transporter ATPase;
69-296 4.14e-08

energy-coupling factor transporter ATPase;


Pssm-ID: 184202 [Multi-domain]  Cd Length: 277  Bit Score: 54.71  E-value: 4.14e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  69 LKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRagtFLGEVYVNGRALRREQFQDC---FSYVLQS-DTLLSSLTV 144
Cdd:PRK13642  23 LNGVSFSITKGEWVSIIGQNGSGKSTTARLIDGLFEE---FEGKVKIDGELLTAENVWNLrrkIGMVFQNpDNQFVGATV 99
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 145 RETLhytALLAIRRGNP-GSFQKKVEAVMAELSLSHVADRlignySLGGISTGERRRVSIAAQLLQDPKVMLFDEPTTGL 223
Cdd:PRK13642 100 EDDV---AFGMENQGIPrEEMIKRVDEALLAVNMLDFKTR-----EPARLSGGQKQRVAVAGIIALRPEIIILDESTSML 171
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 530367936 224 DCMTANQIVVLLVELARRNRIVVLTIHQPRSELFQlFDKIAILSFGELIFCGTPAEMLDFFND---CGYPCPEHSN 296
Cdd:PRK13642 172 DPTGRQEIMRVIHEIKEKYQLTVLSITHDLDEAAS-SDRILVMKAGEIIKEAAPSELFATSEDmveIGLDVPFSSN 246
PRK11819 PRK11819
putative ABC transporter ATP-binding protein; Reviewed
66-224 4.19e-08

putative ABC transporter ATP-binding protein; Reviewed


Pssm-ID: 236992 [Multi-domain]  Cd Length: 556  Bit Score: 55.90  E-value: 4.19e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  66 RQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMsgrlgrAGT---FLGEVyvngralrreQFQDCFS--YVLQSDTLLS 140
Cdd:PRK11819  20 KQILKDISLSFFPGAKIGVLGLNGAGKSTLLRIM------AGVdkeFEGEA----------RPAPGIKvgYLPQEPQLDP 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 141 SLTVRETL-----HYTALLA------IRRGNPGSFQKKVEAVMAELS--------------LSHVADRL---IGNYSLGG 192
Cdd:PRK11819  84 EKTVRENVeegvaEVKAALDrfneiyAAYAEPDADFDALAAEQGELQeiidaadawdldsqLEIAMDALrcpPWDAKVTK 163
                        170       180       190
                 ....*....|....*....|....*....|..
gi 530367936 193 ISTGERRRVSIAAQLLQDPKVMLFDEPTTGLD 224
Cdd:PRK11819 164 LSGGERRRVALCRLLLEKPDMLLLDEPTNHLD 195
znuC PRK09544
high-affinity zinc transporter ATPase; Reviewed
66-224 6.46e-08

high-affinity zinc transporter ATPase; Reviewed


Pssm-ID: 181939 [Multi-domain]  Cd Length: 251  Bit Score: 53.96  E-value: 6.46e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  66 RQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMsgrlgragtfLGEVYVNGRALRREQfQDCFSYVLQS---DTLLsSL 142
Cdd:PRK09544  17 RRVLSDVSLELKPGKILTLLGPNGAGKSTLVRVV----------LGLVAPDEGVIKRNG-KLRIGYVPQKlylDTTL-PL 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 143 TVRETLhytallairRGNPGSFQKKVEAVMAELSLSHVADrlignYSLGGISTGERRRVSIAAQLLQDPKVMLFDEPTTG 222
Cdd:PRK09544  85 TVNRFL---------RLRPGTKKEDILPALKRVQAGHLID-----APMQKLSGGETQRVLLARALLNRPQLLVLDEPTQG 150

                 ..
gi 530367936 223 LD 224
Cdd:PRK09544 151 VD 152
ycf16 CHL00131
sulfate ABC transporter protein; Validated
65-276 8.72e-08

sulfate ABC transporter protein; Validated


Pssm-ID: 214372 [Multi-domain]  Cd Length: 252  Bit Score: 53.49  E-value: 8.72e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  65 TRQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGTFlGEVYVNGRALRREQFQD--------CFSY----- 131
Cdd:CHL00131  19 ENEILKGLNLSINKGEIHAIMGPNGSGKSTLSKVIAGHPAYKILE-GDILFKGESILDLEPEErahlgiflAFQYpieip 97
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 132 -VLQSDTL-LSSLTVRETLHYTALlairrgNPGSFqkkVEAVMAELSLSHVADRLIGNYSLGGISTGERRRVSIAAQLLQ 209
Cdd:CHL00131  98 gVSNADFLrLAYNSKRKFQGLPEL------DPLEF---LEIINEKLKLVGMDPSFLSRNVNEGFSGGEKKRNEILQMALL 168
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 530367936 210 DPKVMLFDEPTTGLDCMTANQIVVLLVELARRNRIVVLTIHQPRSELFQLFDKIAILSFGELIFCGT 276
Cdd:CHL00131 169 DSELAILDETDSGLDIDALKIIAEGINKLMTSENSIILITHYQRLLDYIKPDYVHVMQNGKIIKTGD 235
PRK10982 PRK10982
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
69-269 1.24e-07

galactose/methyl galaxtoside transporter ATP-binding protein; Provisional


Pssm-ID: 182880 [Multi-domain]  Cd Length: 491  Bit Score: 54.35  E-value: 1.24e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  69 LKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGtflGEVYVNGRALRR----EQFQDCFSYVLQS--------- 135
Cdd:PRK10982 264 IRDVSFDLHKGEILGIAGLVGAKRTDIVETLFGIREKSA---GTITLHGKKINNhnanEAINHGFALVTEErrstgiyay 340
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 136 -DTLLSSL--TVRETLHYTALLAIRRGNpgSFQKKVEAVMAELSLSHVAdrlignySLGGISTGERRRVSIAAQLLQDPK 212
Cdd:PRK10982 341 lDIGFNSLisNIRNYKNKVGLLDNSRMK--SDTQWVIDSMRVKTPGHRT-------QIGSLSGGNQQKVIIGRWLLTQPE 411
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 530367936 213 VMLFDEPTTGLDCMTANQIVVLLVELARRNR-IVVLTIHQPrsELFQLFDKIAILSFG 269
Cdd:PRK10982 412 ILMLDEPTRGIDVGAKFEIYQLIAELAKKDKgIIIISSEMP--ELLGITDRILVMSNG 467
MRP_assoc_pro TIGR00957
multi drug resistance-associated protein (MRP); This model describes multi drug ...
64-282 1.28e-07

multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]


Pssm-ID: 188098 [Multi-domain]  Cd Length: 1522  Bit Score: 54.95  E-value: 1.28e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936    64 WTRQI---LKDVSLYVESGQIMCILGSSGSGKTTLLDAMsgrLGRAGTFLGEVYVNGRAlrreqfqdcfSYVLQSdTLLS 140
Cdd:TIGR00957  646 WARDLpptLNGITFSIPEGALVAVVGQVGCGKSSLLSAL---LAEMDKVEGHVHMKGSV----------AYVPQQ-AWIQ 711
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936   141 SLTVRETLHYTALLairrgNPGSFQKKVEA--VMAELSLSHVADRL-IGNYSLGgISTGERRRVSIAAQLLQDPKVMLFD 217
Cdd:TIGR00957  712 NDSLRENILFGKAL-----NEKYYQQVLEAcaLLPDLEILPSGDRTeIGEKGVN-LSGGQKQRVSLARAVYSNADIYLFD 785
                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 530367936   218 EPTTGLDCMTANQIV--VLLVELARRNRIVVLTIHQpRSELFQLfDKIAILSFGELIFCGTPAEMLD 282
Cdd:TIGR00957  786 DPLSAVDAHVGKHIFehVIGPEGVLKNKTRILVTHG-ISYLPQV-DVIIVMSGGKISEMGSYQELLQ 850
cbiO PRK13650
energy-coupling factor transporter ATPase;
62-286 3.63e-07

energy-coupling factor transporter ATPase;


Pssm-ID: 184209 [Multi-domain]  Cd Length: 279  Bit Score: 52.04  E-value: 3.63e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  62 QQWTRQILKDVSLYVESGQIMCILGSSGSGKTT-------LLDAMSgrlgragtflGEVYVNGRALRREQFQDC---FSY 131
Cdd:PRK13650  16 EDQEKYTLNDVSFHVKQGEWLSIIGHNGSGKSTtvrlidgLLEAES----------GQIIIDGDLLTEENVWDIrhkIGM 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 132 VLQS-DTLLSSLTVRETlhytalLAIRRGNPG-SFQKKVEAVMAELSLSHVAD-------RLIGnyslggistGERRRVS 202
Cdd:PRK13650  86 VFQNpDNQFVGATVEDD------VAFGLENKGiPHEEMKERVNEALELVGMQDfkerepaRLSG---------GQKQRVA 150
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 203 IAAQLLQDPKVMLFDEPTTGLDCMTANQIVVLLVELARRNRIVVLTIHQPRSELfQLFDKIAILSFGELIFCGTPAEMLD 282
Cdd:PRK13650 151 IAGAVAMRPKIIILDEATSMLDPEGRLELIKTIKGIRDDYQMTVISITHDLDEV-ALSDRVLVMKNGQVESTSTPRELFS 229

                 ....
gi 530367936 283 FFND 286
Cdd:PRK13650 230 RGND 233
PRK15079 PRK15079
oligopeptide ABC transporter ATP-binding protein OppF; Provisional
70-240 4.30e-07

oligopeptide ABC transporter ATP-binding protein OppF; Provisional


Pssm-ID: 185037 [Multi-domain]  Cd Length: 331  Bit Score: 52.02  E-value: 4.30e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  70 KDVSLYVESGQIMCILGSSGSGKTT-------LLDAMSGR---LGRAGTFLGEVyvNGRALRRE-Q--FQDCfsyvlqsd 136
Cdd:PRK15079  38 DGVTLRLYEGETLGVVGESGCGKSTfaraiigLVKATDGEvawLGKDLLGMKDD--EWRAVRSDiQmiFQDP-------- 107
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 137 tlLSSLTVRETLHYTALLAIRRGNP----GSFQKKVEAVMAELSLshvADRLIGNYSlGGISTGERRRVSIAAQLLQDPK 212
Cdd:PRK15079 108 --LASLNPRMTIGEIIAEPLRTYHPklsrQEVKDRVKAMMLKVGL---LPNLINRYP-HEFSGGQCQRIGIARALILEPK 181
                        170       180
                 ....*....|....*....|....*...
gi 530367936 213 VMLFDEPTTGLDCMTANQIVVLLVELAR 240
Cdd:PRK15079 182 LIICDEPVSALDVSIQAQVVNLLQQLQR 209
PRK10789 PRK10789
SmdA family multidrug ABC transporter permease/ATP-binding protein;
17-251 6.13e-07

SmdA family multidrug ABC transporter permease/ATP-binding protein;


Pssm-ID: 182732 [Multi-domain]  Cd Length: 569  Bit Score: 52.02  E-value: 6.13e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  17 VNRGS------QSSLEGAPA----TAPEPHSLGILHAsysvshrvrpwwDITS-CRQQWTRQILKDVSLYVESGQIMCIL 85
Cdd:PRK10789 280 VERGSaaysriRAMLAEAPVvkdgSEPVPEGRGELDV------------NIRQfTYPQTDHPALENVNFTLKPGQMLGIC 347
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  86 GSSGSGKTTLLdAMSGRLGRAGTflGEVYVNGRALRREQFQDC---FSYVLQSDTLLSSlTVRETlhytallaIRRGNPG 162
Cdd:PRK10789 348 GPTGSGKSTLL-SLIQRHFDVSE--GDIRFHDIPLTKLQLDSWrsrLAVVSQTPFLFSD-TVANN--------IALGRPD 415
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 163 SFQKKVEAVMaelSLSHVAD---RLIGNY--SLGG----ISTGERRRVSIAAQLLQDPKVMLFDEPTTGLDCMTANQIVV 233
Cdd:PRK10789 416 ATQQEIEHVA---RLASVHDdilRLPQGYdtEVGErgvmLSGGQKQRISIARALLLNAEILILDDALSAVDGRTEHQILH 492
                        250
                 ....*....|....*...
gi 530367936 234 LLVELaRRNRIVVLTIHQ 251
Cdd:PRK10789 493 NLRQW-GEGRTVIISAHR 509
PRK13409 PRK13409
ribosome biogenesis/translation initiation ATPase RLI;
69-224 6.26e-07

ribosome biogenesis/translation initiation ATPase RLI;


Pssm-ID: 184037 [Multi-domain]  Cd Length: 590  Bit Score: 52.12  E-value: 6.26e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  69 LKDVSLYVESGQIMC-----ILGSSGSGKTTLLDAMSGRLG-RAGTFLGEVYVngralrreqfqdcfSYVLQSDTLLSSL 142
Cdd:PRK13409 350 LGDFSLEVEGGEIYEgevigIVGPNGIGKTTFAKLLAGVLKpDEGEVDPELKI--------------SYKPQYIKPDYDG 415
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 143 TVREtlhytaLLAIRRGNPGSFQKKVEaVMAELSLSHVADRlignySLGGISTGERRRVSIAAQLLQDPKVMLFDEPTTG 222
Cdd:PRK13409 416 TVED------LLRSITDDLGSSYYKSE-IIKPLQLERLLDK-----NVKDLSGGELQRVAIAACLSRDADLYLLDEPSAH 483

                 ..
gi 530367936 223 LD 224
Cdd:PRK13409 484 LD 485
PRK10261 PRK10261
glutathione transporter ATP-binding protein; Provisional
65-275 7.15e-07

glutathione transporter ATP-binding protein; Provisional


Pssm-ID: 182342 [Multi-domain]  Cd Length: 623  Bit Score: 52.17  E-value: 7.15e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  65 TRQI--LKDVSLYVESGQIMCILGSSGSGKTTlldamSGR--LGRAGTFLGEVYVNGR-----------ALRREQ---FQ 126
Cdd:PRK10261 334 TREVhaVEKVSFDLWPGETLSLVGESGSGKST-----TGRalLRLVESQGGEIIFNGQridtlspgklqALRRDIqfiFQ 408
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 127 DCFsyvlqsdtllSSLTVRETLHYTALLAIR---RGNPGSFQKKVEAVMAELSL--SHvADRLIGNYslggiSTGERRRV 201
Cdd:PRK10261 409 DPY----------ASLDPRQTVGDSIMEPLRvhgLLPGKAAAARVAWLLERVGLlpEH-AWRYPHEF-----SGGQRQRI 472
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 530367936 202 SIAAQLLQDPKVMLFDEPTTGLDCMTANQIVVLLVELARRNRIVVLTIHQPRSELFQLFDKIAILSFGELIFCG 275
Cdd:PRK10261 473 CIARALALNPKVIIADEAVSALDVSIRGQIINLLLDLQRDFGIAYLFISHDMAVVERISHRVAVMYLGQIVEIG 546
Rli1 COG1245
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ...
50-224 8.48e-07

Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440858 [Multi-domain]  Cd Length: 592  Bit Score: 51.71  E-value: 8.48e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  50 RVRPW---WDITSCRQQWTRQIL----------KDVSLYVESGQIMC-----ILGSSGSGKTTLLDAMSGRLG-RAGTFL 110
Cdd:COG1245  319 RIRDEpieFEVHAPRREKEEETLveypdltksyGGFSLEVEGGEIREgevlgIVGPNGIGKTTFAKILAGVLKpDEGEVD 398
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 111 GEVYVngralrreqfqdcfSY---VLQSDtllSSLTVRETLhytallaiRRGNPGSFQ-KKVEAVMAE-LSLSHVADRli 185
Cdd:COG1245  399 EDLKI--------------SYkpqYISPD---YDGTVEEFL--------RSANTDDFGsSYYKTEIIKpLGLEKLLDK-- 451
                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 530367936 186 gnySLGGISTGERRRVSIAAQLLQDPKVMLFDEPTTGLD 224
Cdd:COG1245  452 ---NVKDLSGGELQRVAIAACLSRDADLYLLDEPSAHLD 487
PRK15093 PRK15093
peptide ABC transporter ATP-binding protein SapD;
193-281 3.01e-06

peptide ABC transporter ATP-binding protein SapD;


Pssm-ID: 185049 [Multi-domain]  Cd Length: 330  Bit Score: 49.42  E-value: 3.01e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 193 ISTGERRRVSIAAQLLQDPKVMLFDEPTTGLDCMTANQIVVLLVELARRNRIVVLTIHQPRSELFQLFDKIAILSFGELI 272
Cdd:PRK15093 159 LTEGECQKVMIAIALANQPRLLIADEPTNAMEPTTQAQIFRLLTRLNQNNNTTILLISHDLQMLSQWADKINVLYCGQTV 238

                 ....*....
gi 530367936 273 FCGTPAEML 281
Cdd:PRK15093 239 ETAPSKELV 247
ABCC_CFTR2 cd03289
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ...
68-251 6.76e-06

ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.


Pssm-ID: 213256 [Multi-domain]  Cd Length: 275  Bit Score: 47.93  E-value: 6.76e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  68 ILKDVSLYVESGQIMCILGSSGSGKTTLLDAmsgrLGRAGTFLGEVYVNG---RALRREQFQDCFSYVLQSDTLLSSlTV 144
Cdd:cd03289   19 VLENISFSISPGQRVGLLGRTGSGKSTLLSA----FLRLLNTEGDIQIDGvswNSVPLQKWRKAFGVIPQKVFIFSG-TF 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 145 RETLhytallairrgNPGSFQKKVE--AVMAELSLSHVADRLIG--NYSL--GG--ISTGERRRVSIAAQLLQDPKVMLF 216
Cdd:cd03289   94 RKNL-----------DPYGKWSDEEiwKVAEEVGLKSVIEQFPGqlDFVLvdGGcvLSHGHKQLMCLARSVLSKAKILLL 162
                        170       180       190
                 ....*....|....*....|....*....|....*
gi 530367936 217 DEPTTGLDCMTAnQIVVLLVELARRNRIVVLTIHQ 251
Cdd:cd03289  163 DEPSAHLDPITY-QVIRKTLKQAFADCTVILSEHR 196
GguA NF040905
sugar ABC transporter ATP-binding protein;
62-272 7.02e-06

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 48.63  E-value: 7.02e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  62 QQWTRQILKDVSLYVESGQIMCILGSSGSGKTTLldAMSgRLGRA-GTFL-GEVYVNGRALR----REQFQDCFSYV--- 132
Cdd:NF040905 269 LHPERKVVDDVSLNVRRGEIVGIAGLMGAGRTEL--AMS-VFGRSyGRNIsGTVFKDGKEVDvstvSDAIDAGLAYVted 345
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 133 -----------LQSDTLLSSLT----------VRETL---HYTALLAIRrgNPGSFQKkveavmaelslshvadrlIGNy 188
Cdd:NF040905 346 rkgyglnliddIKRNITLANLGkvsrrgvideNEEIKvaeEYRKKMNIK--TPSVFQK------------------VGN- 404
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 189 slggISTGERRRVSIAAQLLQDPKVMLFDEPTTGLDCMTANQIVVLLVELARRNRIVVLtIHQPRSELFQLFDKIAILSF 268
Cdd:NF040905 405 ----LSGGNQQKVVLSKWLFTDPDVLILDEPTRGIDVGAKYEIYTIINELAAEGKGVIV-ISSELPELLGMCDRIYVMNE 479

                 ....
gi 530367936 269 GELI 272
Cdd:NF040905 480 GRIT 483
araG PRK11288
L-arabinose ABC transporter ATP-binding protein AraG;
72-247 8.24e-06

L-arabinose ABC transporter ATP-binding protein AraG;


Pssm-ID: 183077 [Multi-domain]  Cd Length: 501  Bit Score: 48.37  E-value: 8.24e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  72 VSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGtflGEVYVNGRALRREQFQDCFS--YVL-----QSDTLLSSLTV 144
Cdd:PRK11288 272 ISFSVRAGEIVGLFGLVGAGRSELMKLLYGATRRTA---GQVYLDGKPIDIRSPRDAIRagIMLcpedrKAEGIIPVHSV 348
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 145 RETLhytALLAIRRGNPGSF--QKKVEAVMAELSLSHV------ADRLIGNyslggISTGERRRVSIAAQLLQDPKVMLF 216
Cdd:PRK11288 349 ADNI---NISARRHHLRAGCliNNRWEAENADRFIRSLniktpsREQLIMN-----LSGGNQQKAILGRWLSEDMKVILL 420
                        170       180       190
                 ....*....|....*....|....*....|.
gi 530367936 217 DEPTTGLDCMTANQIVVLLVELARRNRIVVL 247
Cdd:PRK11288 421 DEPTRGIDVGAKHEIYNVIYELAAQGVAVLF 451
PRK10938 PRK10938
putative molybdenum transport ATP-binding protein ModF; Provisional
73-281 1.13e-05

putative molybdenum transport ATP-binding protein ModF; Provisional


Pssm-ID: 182852 [Multi-domain]  Cd Length: 490  Bit Score: 48.09  E-value: 1.13e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  73 SLYVESGQIMCILGSSGSGKTTLLDAMSGRLgragTFL-GEVYVNGRALRR---EQFQDCFSYVLQSDT--LLS------ 140
Cdd:PRK10938  23 SLTLNAGDSWAFVGANGSGKSALARALAGEL----PLLsGERQSQFSHITRlsfEQLQKLVSDEWQRNNtdMLSpgeddt 98
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 141 SLTVRETLhytaLLAIRRGNpgsfqkKVEAVMAELSLSHVADRLIgNYslggISTGERRRVSIAAQLLQDPKVMLFDEPT 220
Cdd:PRK10938  99 GRTTAEII----QDEVKDPA------RCEQLAQQFGITALLDRRF-KY----LSTGETRKTLLCQALMSEPDLLILDEPF 163
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 530367936 221 TGLDCMTANQIVVLLVELARRNRIVVLTIHQpRSELFQLFDKIAILSFGELIFCGTPAEML 281
Cdd:PRK10938 164 DGLDVASRQQLAELLASLHQSGITLVLVLNR-FDEIPDFVQFAGVLADCTLAETGEREEIL 223
PRK11147 PRK11147
ABC transporter ATPase component; Reviewed
68-224 1.16e-05

ABC transporter ATPase component; Reviewed


Pssm-ID: 236861 [Multi-domain]  Cd Length: 635  Bit Score: 48.02  E-value: 1.16e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  68 ILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSG------------------RLG----RAGTflGEVY------VNGRA 119
Cdd:PRK11147  18 LLDNAELHIEDNERVCLVGRNGAGKSTLMKILNGevllddgriiyeqdlivaRLQqdppRNVE--GTVYdfvaegIEEQA 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 120 LRREQFQDCFSYVLQ--SDTLLSSL-TVRETLHYTallairrgNPGSFQKKVEAVMAELSLShvadrliGNYSLGGISTG 196
Cdd:PRK11147  96 EYLKRYHDISHLVETdpSEKNLNELaKLQEQLDHH--------NLWQLENRINEVLAQLGLD-------PDAALSSLSGG 160
                        170       180
                 ....*....|....*....|....*...
gi 530367936 197 ERRRVSIAAQLLQDPKVMLFDEPTTGLD 224
Cdd:PRK11147 161 WLRKAALGRALVSNPDVLLLDEPTNHLD 188
ABCC_SUR2 cd03288
ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The ...
66-281 1.21e-05

ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The sulfonylurea receptor SUR is an ATP binding cassette (ABC) protein of the ABCC/MRP family. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.


Pssm-ID: 213255 [Multi-domain]  Cd Length: 257  Bit Score: 47.21  E-value: 1.21e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  66 RQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMsgrLGRAGTFLGEVYVNG---RALRREQFQDCFSYVLQsDTLLSSL 142
Cdd:cd03288   34 KPVLKHVKAYIKPGQKVGICGRTGSGKSSLSLAF---FRMVDIFDGKIVIDGidiSKLPLHTLRSRLSIILQ-DPILFSG 109
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 143 TVR---------------ETLHYTALLAIRRGNPGSfqkkVEAVMAElslshvadrlignyslGG--ISTGERRRVSIAA 205
Cdd:cd03288  110 SIRfnldpeckctddrlwEALEIAQLKNMVKSLPGG----LDAVVTE----------------GGenFSVGQRQLFCLAR 169
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 530367936 206 QLLQDPKVMLFDEPTTGLDCMTANqIVVLLVELARRNRIVVLTIHQPRSELFQlfDKIAILSFGELIFCGTPAEML 281
Cdd:cd03288  170 AFVRKSSILIMDEATASIDMATEN-ILQKVVMTAFADRTVVTIAHRVSTILDA--DLVLVLSRGILVECDTPENLL 242
PTZ00265 PTZ00265
multidrug resistance protein (mdr1); Provisional
176-267 2.74e-05

multidrug resistance protein (mdr1); Provisional


Pssm-ID: 240339 [Multi-domain]  Cd Length: 1466  Bit Score: 47.33  E-value: 2.74e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  176 SLSHVADRLIGNYSlGGISTGERRRVSIAAQLLQDPKVMLFDEPTTGLDCMTANQIVVLLVELARRNRIVVLTIHQpRSE 255
Cdd:PTZ00265 1343 SLPNKYDTNVGPYG-KSLSGGQKQRIAIARALLREPKILLLDEATSSLDSNSEKLIEKTIVDIKDKADKTIITIAH-RIA 1420
                          90
                  ....*....|..
gi 530367936  256 LFQLFDKIAILS 267
Cdd:PTZ00265 1421 SIKRSDKIVVFN 1432
PvdE COG4615
ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion ...
72-218 3.22e-05

ABC-type siderophore export system, fused ATPase and permease components [Inorganic ion transport and metabolism];


Pssm-ID: 443659 [Multi-domain]  Cd Length: 547  Bit Score: 46.71  E-value: 3.22e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  72 VSLYVESGQIMCILGSSGSGKTTLLDAMSGrLGRAGTflGEVYVNGRAL---RREQFQDCFSYVLqSDTLLssltvretl 148
Cdd:COG4615  351 IDLTIRRGELVFIVGGNGSGKSTLAKLLTG-LYRPES--GEILLDGQPVtadNREAYRQLFSAVF-SDFHL--------- 417
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 530367936 149 hYTALLAIrrgNPGSFQKKVEAVMAELSLSH---VADRLIGNYSLggiSTGERRRVSIAAQLLQDPKVMLFDE 218
Cdd:COG4615  418 -FDRLLGL---DGEADPARARELLERLELDHkvsVEDGRFSTTDL---SQGQRKRLALLVALLEDRPILVFDE 483
sufC PRK09580
cysteine desulfurase ATPase component; Reviewed
66-253 3.24e-05

cysteine desulfurase ATPase component; Reviewed


Pssm-ID: 181965 [Multi-domain]  Cd Length: 248  Bit Score: 45.55  E-value: 3.24e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  66 RQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGTFlGEVYVNGRALRREQFQD--------CFSYVLQ--- 134
Cdd:PRK09580  14 KAILRGLNLEVRPGEVHAIMGPNGSGKSTLSATLAGREDYEVTG-GTVEFKGKDLLELSPEDragegifmAFQYPVEipg 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 135 -SDTLLSSLTVRETLHYTALLAIRRGNpgsFQKKVEAVMAELSLShvADRLIGNYSLgGISTGERRRVSIAAQLLQDPKV 213
Cdd:PRK09580  93 vSNQFFLQTALNAVRSYRGQEPLDRFD---FQDLMEEKIALLKMP--EDLLTRSVNV-GFSGGEKKRNDILQMAVLEPEL 166
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 530367936 214 MLFDEPTTGLDcMTANQIVVLLVELARR-NRIVVLTIHQPR 253
Cdd:PRK09580 167 CILDESDSGLD-IDALKIVADGVNSLRDgKRSFIIVTHYQR 206
PLN03232 PLN03232
ABC transporter C family member; Provisional
68-281 4.97e-05

ABC transporter C family member; Provisional


Pssm-ID: 215640 [Multi-domain]  Cd Length: 1495  Bit Score: 46.51  E-value: 4.97e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936   68 ILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSgRLGRAGTflGEVYVNGRALRREQFQD---CFSYVLQSDTLLSSlTV 144
Cdd:PLN03232 1251 VLHGLSFFVSPSEKVGVVGRTGAGKSSMLNALF-RIVELEK--GRIMIDDCDVAKFGLTDlrrVLSIIPQSPVLFSG-TV 1326
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  145 RETLhytallairrgNPgsFQKKVEAVMAE-LSLSHVADrLIGNYSLG----------GISTGERRRVSIAAQLLQDPKV 213
Cdd:PLN03232 1327 RFNI-----------DP--FSEHNDADLWEaLERAHIKD-VIDRNPFGldaevseggeNFSVGQRQLLSLARALLRRSKI 1392
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 530367936  214 MLFDEPTTGLDCMTANQIVVLLVELARRNRIVVLTiHqpRSELFQLFDKIAILSFGELIFCGTPAEML 281
Cdd:PLN03232 1393 LVLDEATASVDVRTDSLIQRTIREEFKSCTMLVIA-H--RLNTIIDCDKILVLSSGQVLEYDSPQELL 1457
PRK10261 PRK10261
glutathione transporter ATP-binding protein; Provisional
69-276 5.12e-05

glutathione transporter ATP-binding protein; Provisional


Pssm-ID: 182342 [Multi-domain]  Cd Length: 623  Bit Score: 46.00  E-value: 5.12e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  69 LKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGRAGtflGEVYVNGRALRR---------EQFQDCFSYVLQSDTLL 139
Cdd:PRK10261  32 VRNLSFSLQRGETLAIVGESGSGKSVTALALMRLLEQAG---GLVQCDKMLLRRrsrqvielsEQSAAQMRHVRGADMAM 108
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 140 ------SSLTVRETLHYTALLAIRRGNPGSFQKKVEAVMAELSLSHV--ADRLIGNYSlGGISTGERRRVSIAAQLLQDP 211
Cdd:PRK10261 109 ifqepmTSLNPVFTVGEQIAESIRLHQGASREEAMVEAKRMLDQVRIpeAQTILSRYP-HQLSGGMRQRVMIAMALSCRP 187
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 530367936 212 KVMLFDEPTTGLDCMTANQIVVLLVELARRNRIVVLTIHQPRSELFQLFDKIAILSFGELIFCGT 276
Cdd:PRK10261 188 AVLIADEPTTALDVTIQAQILQLIKVLQKEMSMGVIFITHDMGVVAEIADRVLVMYQGEAVETGS 252
PRK10790 PRK10790
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;
66-281 8.22e-05

SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;


Pssm-ID: 182733 [Multi-domain]  Cd Length: 592  Bit Score: 45.48  E-value: 8.22e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  66 RQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMsgrLGRAGTFLGEVYVNGR--------ALRRE----QfQDCfsyVL 133
Cdd:PRK10790 354 NLVLQNINLSVPSRGFVALVGHTGSGKSTLASLL---MGYYPLTEGEIRLDGRplsslshsVLRQGvamvQ-QDP---VV 426
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 134 QSDTLLSSLTVretlhytallairrGNPGSfQKKVEAVMAELSLSHVADRLI-GNYSLGG-----ISTGERRRVSIAAQL 207
Cdd:PRK10790 427 LADTFLANVTL--------------GRDIS-EEQVWQALETVQLAELARSLPdGLYTPLGeqgnnLSVGQKQLLALARVL 491
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 530367936 208 LQDPKVMLFDEPTTGLDCMTANQIVVLLVELARRNRIVVL-----TIHQPrselfqlfDKIAILSFGELIFCGTPAEML 281
Cdd:PRK10790 492 VQTPQILILDEATANIDSGTEQAIQQALAAVREHTTLVVIahrlsTIVEA--------DTILVLHRGQAVEQGTHQQLL 562
ABC_UvrA cd03238
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in ...
69-253 1.48e-04

ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.


Pssm-ID: 213205 [Multi-domain]  Cd Length: 176  Bit Score: 42.70  E-value: 1.48e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  69 LKDVSLYVESGQIMCILGSSGSGKTTLLdamsgrlgragtflgevyvngralrreqfQDCFSYVLQSdTLLSSLTVREtl 148
Cdd:cd03238   11 LQNLDVSIPLNVLVVVTGVSGSGKSTLV-----------------------------NEGLYASGKA-RLISFLPKFS-- 58
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 149 hYTALLAIrrgnpGSFQKKVEAVMAELSLshvadrligNYSLGGISTGERRRVSIAAQLLQDPK--VMLFDEPTTGLDCM 226
Cdd:cd03238   59 -RNKLIFI-----DQLQFLIDVGLGYLTL---------GQKLSTLSGGELQRVKLASELFSEPPgtLFILDEPSTGLHQQ 123
                        170       180
                 ....*....|....*....|....*..
gi 530367936 227 TANQIVVLLVELARRNRIVVLTIHQPR 253
Cdd:cd03238  124 DINQLLEVIKGLIDLGNTVILIEHNLD 150
ABC_Class2 cd03227
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems ...
78-268 3.56e-04

ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterized by the fact that the ABC subunit is made up of duplicated, fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins.


Pssm-ID: 213194 [Multi-domain]  Cd Length: 162  Bit Score: 41.19  E-value: 3.56e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  78 SGQIMCILGSSGSGKTTLLDAMSGRLGRAGTFLGevyvngralRREQFQdcfsyvlqsdtllssltvretlhytallair 157
Cdd:cd03227   20 EGSLTIITGPNGSGKSTILDAIGLALGGAQSATR---------RRSGVK------------------------------- 59
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936 158 rgnPGSFqkkVEAVMAELslshvadrligNYSLGGISTGERRRVSIAAQL----LQDPKVMLFDEPTTGLDCMTANQIVV 233
Cdd:cd03227   60 ---AGCI---VAAVSAEL-----------IFTRLQLSGGEKELSALALILalasLKPRPLYILDEIDRGLDPRDGQALAE 122
                        170       180       190
                 ....*....|....*....|....*....|....*
gi 530367936 234 LLVELARRNRIVVLTIHQPrsELFQLFDKIAILSF 268
Cdd:cd03227  123 AILEHLVKGAQVIVITHLP--ELAELADKLIHIKK 155
PTZ00243 PTZ00243
ABC transporter; Provisional
68-280 5.80e-04

ABC transporter; Provisional


Pssm-ID: 240327 [Multi-domain]  Cd Length: 1560  Bit Score: 42.84  E-value: 5.80e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936   68 ILKDVSLYVESGQIMCILGSSGSGKTTLLDamsgrlgragTFL-------GEVYVNGR--------ALRREqfqdcFSYV 132
Cdd:PTZ00243 1325 VLRGVSFRIAPREKVGIVGRTGSGKSTLLL----------TFMrmvevcgGEIRVNGReigayglrELRRQ-----FSMI 1389
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  133 LQsDTLLSSLTVRETLhytallairrgNPGSfQKKVEAVMAELSL----SHVADRLIG----------NYSLGgistgER 198
Cdd:PTZ00243 1390 PQ-DPVLFDGTVRQNV-----------DPFL-EASSAEVWAALELvglrERVASESEGidsrvleggsNYSVG-----QR 1451
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530367936  199 RRVSIAAQLLQ-DPKVMLFDEPTTGLDCMTANQIVVLlVELARRNRIVVLTIHqpRSELFQLFDKIAILSFGELIFCGTP 277
Cdd:PTZ00243 1452 QLMCMARALLKkGSGFILMDEATANIDPALDRQIQAT-VMSAFSAYTVITIAH--RLHTVAQYDKIIVMDHGAVAEMGSP 1528

                  ...
gi 530367936  278 AEM 280
Cdd:PTZ00243 1529 REL 1531
GguA NF040905
sugar ABC transporter ATP-binding protein;
69-121 6.25e-04

sugar ABC transporter ATP-binding protein;


Pssm-ID: 468840 [Multi-domain]  Cd Length: 500  Bit Score: 42.47  E-value: 6.25e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 530367936  69 LKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRLGrAGTFLGEVYVNGRALR 121
Cdd:NF040905  17 LDDVNLSVREGEIHALCGENGAGKSTLMKVLSGVYP-HGSYEGEILFDGEVCR 68
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
78-127 7.47e-04

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 40.05  E-value: 7.47e-04
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|
gi 530367936    78 SGQIMCILGSSGSGKTTLLDAMSGRLGRAGTflGEVYVNGRALRREQFQD 127
Cdd:smart00382   1 PGEVILIVGPPGSGKTTLARALARELGPPGG--GVIYIDGEDILEEVLDQ 48
PTZ00265 PTZ00265
multidrug resistance protein (mdr1); Provisional
176-251 1.34e-03

multidrug resistance protein (mdr1); Provisional


Pssm-ID: 240339 [Multi-domain]  Cd Length: 1466  Bit Score: 41.94  E-value: 1.34e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 530367936  176 SLSHVADRLIGNySLGGISTGERRRVSIAAQLLQDPKVMLFDEPTTGLDCMTANQIVVLLVEL-ARRNRIVVLTIHQ 251
Cdd:PTZ00265  564 ALPDKYETLVGS-NASKLSGGQKQRISIARAIIRNPKILILDEATSSLDNKSEYLVQKTINNLkGNENRITIIIAHR 639
EF-G_bact cd04170
Elongation factor G (EF-G) family; Translocation is mediated by EF-G (also called translocase). ...
84-108 1.64e-03

Elongation factor G (EF-G) family; Translocation is mediated by EF-G (also called translocase). The structure of EF-G closely resembles that of the complex between EF-Tu and tRNA. This is an example of molecular mimicry; a protein domain evolved so that it mimics the shape of a tRNA molecule. EF-G in the GTP form binds to the ribosome, primarily through the interaction of its EF-Tu-like domain with the 50S subunit. The binding of EF-G to the ribosome in this manner stimulates the GTPase activity of EF-G. On GTP hydrolysis, EF-G undergoes a conformational change that forces its arm deeper into the A site on the 30S subunit. To accommodate this domain, the peptidyl-tRNA in the A site moves to the P site, carrying the mRNA and the deacylated tRNA with it. The ribosome may be prepared for these rearrangements by the initial binding of EF-G as well. The dissociation of EF-G leaves the ribosome ready to accept the next aminoacyl-tRNA into the A site. This group contains only bacterial members.


Pssm-ID: 206733 [Multi-domain]  Cd Length: 268  Bit Score: 40.65  E-value: 1.64e-03
                         10        20
                 ....*....|....*....|....*...
gi 530367936  84 ILGSSGSGKTTLLDAM---SGRLGRAGT 108
Cdd:cd04170    4 LVGHSGSGKTTLAEALlyaTGAIDRLGR 31
ABC_RNaseL_inhibitor cd03222
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a ...
193-246 2.78e-03

ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins, and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains, which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.


Pssm-ID: 213189 [Multi-domain]  Cd Length: 177  Bit Score: 39.09  E-value: 2.78e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 530367936 193 ISTGERRRVSIAAQLLQDPKVMLFDEPTTGLDC---MTANQIVVLLVELARRNRIVV 246
Cdd:cd03222   72 LSGGELQRVAIAAALLRNATFYLFDEPSAYLDIeqrLNAARAIRRLSEEGKKTALVV 128
PRK15064 PRK15064
ABC transporter ATP-binding protein; Provisional
66-103 5.64e-03

ABC transporter ATP-binding protein; Provisional


Pssm-ID: 237894 [Multi-domain]  Cd Length: 530  Bit Score: 39.49  E-value: 5.64e-03
                         10        20        30
                 ....*....|....*....|....*....|....*...
gi 530367936  66 RQILKDVSLYVESGQIMCILGSSGSGKTTLLDAMSGRL 103
Cdd:PRK15064 332 GPLFKNLNLLLEAGERLAIIGENGVGKTTLLRTLVGEL 369
uvra TIGR00630
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ...
69-108 6.37e-03

excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273184 [Multi-domain]  Cd Length: 925  Bit Score: 39.61  E-value: 6.37e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 530367936   69 LKDVSLYVESGQIMCILGSSGSGKTTLLD-----AMSGRLGRAGT 108
Cdd:TIGR00630 624 LKNITVSIPLGLFTCITGVSGSGKSTLINdtlypALANRLNGAKT 668
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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