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Conserved domains on  [gi|530372322|ref|XP_005265128|]
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golgin subfamily A member 4 isoform X3 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1501-2142 1.21e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 80.49  E-value: 1.21e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1501 KKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRfdclKGEMEDDKSKMEKKESNLETELKSQTA 1580
Cdd:TIGR02168  248 LKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANE----ISRLEQQKQILRERLANLERQLEELEA 323

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1581 RIMELEDHITQKTIEIESLN---EVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELE 1657
Cdd:TIGR02168  324 QLEELESKLDELAEELAELEeklEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIE 403

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1658 TKKKELEHVNLSVKSKEEELKALEDRLESesaAKLAELKRKAEQKIAAIKKqLLSQMEEKEEQYKKGTEShLSELNTKLQ 1737
Cdd:TIGR02168  404 RLEARLERLEDRRERLQQEIEELLKKLEE---AELKELQAELEELEEELEE-LQEELERLEEALEELREE-LEEAEQALD 478

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1738 EREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQeEADSQGC------VQKTYEEKIS---------VLQRNLTE 1802
Cdd:TIGR02168  479 AAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSG-LSGILGVlselisVDEGYEAAIEaalggrlqaVVVENLNA 557

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1803 KEKLLQrvGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHED--------------------QSMIGH------LQEEL 1856
Cdd:TIGR02168  558 AKKAIA--FLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEgflgvakdlvkfdpklrkalSYLLGGvlvvddLDNAL 635

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1857 EEKNKKYS----------LIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKELdsclvrQKEVHR 1926
Cdd:TIGR02168  636 ELAKKLRPgyrivtldgdLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAEL------RKELEE 709

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1927 VEMEELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQK 2006
Cdd:TIGR02168  710 LEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEA 789

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  2007 DLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIkETINKAQEVEAELL 2086
Cdd:TIGR02168  790 QIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDI-ESLAAEIEELEELI 868

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 530372322  2087 ESHQEETNQLLKKIAEKDDDLKRTAKRYEEiLDAREEEMTAKVRDLQTQLEELQKK 2142
Cdd:TIGR02168  869 EELESELEALLNERASLEEALALLRSELEE-LSEELRELESKRSELRRELEELREK 923
SMC_prok_B super family cl37069
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 796-1720 2.99e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


The actual alignment was detected with superfamily member TIGR02168:

Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 78.95  E-value: 2.99e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   796 KEHEVSIQRTEKALKdqinQLELLLKERDKHLKEHQAHVENLEA--DIKRSEGELQQASAKLDV--FQSYQSATHEQTKA 871
Cdd:TIGR02168  175 KETERKLERTRENLD----RLEDILNELERQLKSLERQAEKAERykELKAELRELELALLVLRLeeLREELEELQEELKE 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   872 YEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGN 951
Cdd:TIGR02168  251 AEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELES 330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   952 KEQEQTKqilvekenmILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQEtlkkklld 1031
Cdd:TIGR02168  331 KLDELAE---------ELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLEL-------- 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1032 QEAKLKKELENTALELSQkekqfnakmlemaqansagISDAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAE 1111
Cdd:TIGR02168  394 QIASLNNEIERLEARLER-------------------LEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQE 454

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1112 ELqEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEegvkqdttlneLQEQLKQKSAHVNSLAQDETKLKAHL 1191
Cdd:TIGR02168  455 EL-ERLEEALEELREELEEAEQALDAAERELAQLQARLDSLER-----------LQENLEGFSEGVKALLKNQSGLSGIL 522

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1192 ----EKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEE 1267
Cdd:TIGR02168  523 gvlsELISVDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLG 602

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1268 LAIQLDICCKKTEALLeaktnelinisssktNAILSRISHCQhrttkvkealliktctvseleaqlrqlteeqntlniSF 1347
Cdd:TIGR02168  603 VAKDLVKFDPKLRKAL---------------SYLLGGVLVVD------------------------------------DL 631

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1348 QQATHQLEEKENQiksmkadiESLVTEKEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSL 1427
Cdd:TIGR02168  632 DNALELAKKLRPG--------YRIVTLDGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAEL 703

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1428 SKQLTDLNVQL-QNSISLSEKEAAISSLRKQYDEEKCE---LLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKK 1503
Cdd:TIGR02168  704 RKELEELEEELeQLRKELEELSRQISALRKDLARLEAEveqLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAE 783

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1504 AQSRftqhQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEkkesNLETELKSQTARIM 1583
Cdd:TIGR02168  784 IEEL----EAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLE----DLEEQIEELSEDIE 855

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1584 ELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGE---EKDNRVKEAEEKILTLENQVYSMKAELETKK 1660
Cdd:TIGR02168  856 SLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEelrELESKRSELRRELEELREKLAQLELRLEGLE 935

                          890       900       910       920       930       940
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 530372322  1661 KELEHVNLSVKSK----EEELKALEDRLESESAAKLAELKRkAEQKIAAIKKQLLSQMEEKEEQ 1720
Cdd:TIGR02168  936 VRIDNLQERLSEEysltLEEAEALENKIEDDEEEARRRLKR-LENKIKELGPVNLAAIEEYEEL 998
PTZ00121 super family cl31754
MAEBL; Provisional
 370-1052 3.90e-13

MAEBL; Provisional


The actual alignment was detected with superfamily member PTZ00121:

Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 75.56  E-value: 3.90e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  370 EKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAknlieqlEQDKGMVIAetkRQMHETLEMKEEEIAQLRSRIKQm 449
Cdd:PTZ00121 1112 EEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKA-------EDAKRVEIA---RKAEDARKAEEARKAEDAKKAEA- 1180

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  450 TTQGEELREQKE--KSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDvMKK 527
Cdd:PTZ00121 1181 ARKAEEVRKAEElrKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRK-FEE 1259

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  528 SSEEQIAKLQKLHEKELARKEQELTKKLQTRErefQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKK---AILT 604
Cdd:PTZ00121 1260 ARMAHFARRQAAIKAEEARKADELKKAEEKKK---ADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKkadAAKK 1336

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  605 ESENKLRDLQQEAETYRTRILELESSLEKS----LQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDA 680
Cdd:PTZ00121 1337 KAEEAKKAAEAAKAEAEAAADEAEAAEEKAeaaeKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAA 1416

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  681 LWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLE--KLDVKQTELESLSSELSEVLKARHKL 758
Cdd:PTZ00121 1417 KKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEakKADEAKKKAEEAKKADEAKKKAEEAK 1496

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  759 EEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLE 838
Cdd:PTZ00121 1497 KKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDK 1576

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  839 ADIKRSEGELQQASAKldvfqsyqsATHEQTKAYEEQLAQLQQKLLDLETERILLTK-QVAEVEAQKKDVCTELDAHKIQ 917
Cdd:PTZ00121 1577 NMALRKAEEAKKAEEA---------RIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEElKKAEEEKKKVEQLKKKEAEEKK 1647

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  918 VQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQilveKENMILQMREGQKKEIEILTQKLSAKEDSIHILN 997
Cdd:PTZ00121 1648 KAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKK----AAEALKKEAEEAKKAEELKKKEAEEKKKAEELKK 1723

                         650       660       670       680       690
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 530372322  998 EEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEK 1052
Cdd:PTZ00121 1724 AEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKE 1778
Grip smart00755
golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;
2220-2263 5.55e-08

golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;


:

Pssm-ID: 197860  Cd Length: 46  Bit Score: 50.68  E-value: 5.55e-08
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*.
gi 530372322   2220 PTEFEYLRKVLFEYMMGRET--KTMAKVITTVLKFPDDQTQKILER 2263
Cdd:smart00755    1 EANFEYLKNVLLQFLTLRESerETLLPVISTVLQLSPEEMQKLLEV 46
SMC_N super family cl47134
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 191-507 1.32e-06

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


The actual alignment was detected with superfamily member TIGR02169:

Pssm-ID: 481474 [Multi-domain]  Cd Length: 1164  Bit Score: 53.92  E-value: 1.32e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   191 KEQLIQRLRRMERSLSSYRGKYSElvtAYQMLqREKKKLQGILSQSQDKSLRRIAELREELQMDQQ---AKKHLQEEFDA 267
Cdd:TIGR02169  690 LSSLQSELRRIENRLDELSQELSD---ASRKI-GEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQeieNVKSELKELEA 765

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   268 SLEEKDQYISVLQTQVSLLKQRLRNGPMNV------DVLKPLPQLEPQAEVFTKEENPESDGEPVVEDgtSVKTLETLQQ 341
Cdd:TIGR02169  766 RIEELEEDLHKLEEALNDLEARLSHSRIPEiqaelsKLEEEVSRIEARLREIEQKLNRLTLEKEYLEK--EIQELQEQRI 843

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   342 RVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGmvi 421
Cdd:TIGR02169  844 DLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLS--- 920

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   422 aetkrQMHETLEMKEEEIAQLRSRIKQMTTQGEE------LREQKEKSERA----------AFEELEKALSTAQKTEEAR 485
Cdd:TIGR02169  921 -----ELKAKLEALEEELSEIEDPKGEDEEIPEEelsledVQAELQRVEEEiralepvnmlAIQEYEEVLKRLDELKEKR 995

                          330       340
                   ....*....|....*....|..
gi 530372322   486 RKLKAEMDEQIKTIEKTSEEER 507
Cdd:TIGR02169  996 AKLEEERKAILERIEEYEKKKR 1017
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1501-2142 1.21e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 80.49  E-value: 1.21e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1501 KKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRfdclKGEMEDDKSKMEKKESNLETELKSQTA 1580
Cdd:TIGR02168  248 LKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANE----ISRLEQQKQILRERLANLERQLEELEA 323

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1581 RIMELEDHITQKTIEIESLN---EVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELE 1657
Cdd:TIGR02168  324 QLEELESKLDELAEELAELEeklEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIE 403

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1658 TKKKELEHVNLSVKSKEEELKALEDRLESesaAKLAELKRKAEQKIAAIKKqLLSQMEEKEEQYKKGTEShLSELNTKLQ 1737
Cdd:TIGR02168  404 RLEARLERLEDRRERLQQEIEELLKKLEE---AELKELQAELEELEEELEE-LQEELERLEEALEELREE-LEEAEQALD 478

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1738 EREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQeEADSQGC------VQKTYEEKIS---------VLQRNLTE 1802
Cdd:TIGR02168  479 AAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSG-LSGILGVlselisVDEGYEAAIEaalggrlqaVVVENLNA 557

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1803 KEKLLQrvGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHED--------------------QSMIGH------LQEEL 1856
Cdd:TIGR02168  558 AKKAIA--FLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEgflgvakdlvkfdpklrkalSYLLGGvlvvddLDNAL 635

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1857 EEKNKKYS----------LIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKELdsclvrQKEVHR 1926
Cdd:TIGR02168  636 ELAKKLRPgyrivtldgdLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAEL------RKELEE 709

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1927 VEMEELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQK 2006
Cdd:TIGR02168  710 LEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEA 789

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  2007 DLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIkETINKAQEVEAELL 2086
Cdd:TIGR02168  790 QIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDI-ESLAAEIEELEELI 868

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 530372322  2087 ESHQEETNQLLKKIAEKDDDLKRTAKRYEEiLDAREEEMTAKVRDLQTQLEELQKK 2142
Cdd:TIGR02168  869 EELESELEALLNERASLEEALALLRSELEE-LSEELRELESKRSELRRELEELREK 923
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 796-1720 2.99e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 78.95  E-value: 2.99e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   796 KEHEVSIQRTEKALKdqinQLELLLKERDKHLKEHQAHVENLEA--DIKRSEGELQQASAKLDV--FQSYQSATHEQTKA 871
Cdd:TIGR02168  175 KETERKLERTRENLD----RLEDILNELERQLKSLERQAEKAERykELKAELRELELALLVLRLeeLREELEELQEELKE 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   872 YEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGN 951
Cdd:TIGR02168  251 AEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELES 330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   952 KEQEQTKqilvekenmILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQEtlkkklld 1031
Cdd:TIGR02168  331 KLDELAE---------ELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLEL-------- 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1032 QEAKLKKELENTALELSQkekqfnakmlemaqansagISDAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAE 1111
Cdd:TIGR02168  394 QIASLNNEIERLEARLER-------------------LEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQE 454

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1112 ELqEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEegvkqdttlneLQEQLKQKSAHVNSLAQDETKLKAHL 1191
Cdd:TIGR02168  455 EL-ERLEEALEELREELEEAEQALDAAERELAQLQARLDSLER-----------LQENLEGFSEGVKALLKNQSGLSGIL 522

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1192 ----EKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEE 1267
Cdd:TIGR02168  523 gvlsELISVDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLG 602

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1268 LAIQLDICCKKTEALLeaktnelinisssktNAILSRISHCQhrttkvkealliktctvseleaqlrqlteeqntlniSF 1347
Cdd:TIGR02168  603 VAKDLVKFDPKLRKAL---------------SYLLGGVLVVD------------------------------------DL 631

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1348 QQATHQLEEKENQiksmkadiESLVTEKEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSL 1427
Cdd:TIGR02168  632 DNALELAKKLRPG--------YRIVTLDGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAEL 703

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1428 SKQLTDLNVQL-QNSISLSEKEAAISSLRKQYDEEKCE---LLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKK 1503
Cdd:TIGR02168  704 RKELEELEEELeQLRKELEELSRQISALRKDLARLEAEveqLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAE 783

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1504 AQSRftqhQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEkkesNLETELKSQTARIM 1583
Cdd:TIGR02168  784 IEEL----EAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLE----DLEEQIEELSEDIE 855

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1584 ELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGE---EKDNRVKEAEEKILTLENQVYSMKAELETKK 1660
Cdd:TIGR02168  856 SLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEelrELESKRSELRRELEELREKLAQLELRLEGLE 935

                          890       900       910       920       930       940
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 530372322  1661 KELEHVNLSVKSK----EEELKALEDRLESESAAKLAELKRkAEQKIAAIKKQLLSQMEEKEEQ 1720
Cdd:TIGR02168  936 VRIDNLQERLSEEysltLEEAEALENKIEDDEEEARRRLKR-LENKIKELGPVNLAAIEEYEEL 998
PTZ00121 PTZ00121
MAEBL; Provisional
 370-1052 3.90e-13

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 75.56  E-value: 3.90e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  370 EKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAknlieqlEQDKGMVIAetkRQMHETLEMKEEEIAQLRSRIKQm 449
Cdd:PTZ00121 1112 EEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKA-------EDAKRVEIA---RKAEDARKAEEARKAEDAKKAEA- 1180

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  450 TTQGEELREQKE--KSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDvMKK 527
Cdd:PTZ00121 1181 ARKAEEVRKAEElrKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRK-FEE 1259

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  528 SSEEQIAKLQKLHEKELARKEQELTKKLQTRErefQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKK---AILT 604
Cdd:PTZ00121 1260 ARMAHFARRQAAIKAEEARKADELKKAEEKKK---ADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKkadAAKK 1336

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  605 ESENKLRDLQQEAETYRTRILELESSLEKS----LQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDA 680
Cdd:PTZ00121 1337 KAEEAKKAAEAAKAEAEAAADEAEAAEEKAeaaeKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAA 1416

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  681 LWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLE--KLDVKQTELESLSSELSEVLKARHKL 758
Cdd:PTZ00121 1417 KKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEakKADEAKKKAEEAKKADEAKKKAEEAK 1496

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  759 EEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLE 838
Cdd:PTZ00121 1497 KKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDK 1576

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  839 ADIKRSEGELQQASAKldvfqsyqsATHEQTKAYEEQLAQLQQKLLDLETERILLTK-QVAEVEAQKKDVCTELDAHKIQ 917
Cdd:PTZ00121 1577 NMALRKAEEAKKAEEA---------RIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEElKKAEEEKKKVEQLKKKEAEEKK 1647

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  918 VQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQilveKENMILQMREGQKKEIEILTQKLSAKEDSIHILN 997
Cdd:PTZ00121 1648 KAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKK----AAEALKKEAEEAKKAEELKKKEAEEKKKAEELKK 1723

                         650       660       670       680       690
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 530372322  998 EEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEK 1052
Cdd:PTZ00121 1724 AEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKE 1778
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 334-856 5.58e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 71.51  E-value: 5.58e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  334 KTLETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDE----------RLQELEKIKDLHMAEKTKLITQL 403
Cdd:COG1196   239 AELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEaqaeeyellaELARLEQDIARLEERRRELEERL 318

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  404 RDAKNLIEQLEQDKGMVIAETKRQmHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEE 483
Cdd:COG1196   319 EELEEELAELEEELEELEEELEEL-EEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAE 397

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  484 ARRKLK--AEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTRERE 561
Cdd:COG1196   398 LAAQLEelEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEA 477

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  562 FQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQ 641
Cdd:COG1196   478 ALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDE 557

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  642 SKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQA 721
Cdd:COG1196   558 VAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALR 637

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  722 HIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVS 801
Cdd:COG1196   638 RAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERL 717

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 530372322  802 IQRTEKALKDQinQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLD 856
Cdd:COG1196   718 EEELEEEALEE--QLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELE 770
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 342-1027 1.84e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 70.09  E-value: 1.84e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   342 RVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDE-RLQELEKIKDLHMAEKTklitqLRDAKNLIEQLEQDKgMV 420
Cdd:TIGR02168  233 RLEELREELEELQEELKEAEEELEELTAELQELEEKLEElRLEVSELEEEIEELQKE-----LYALANEISRLEQQK-QI 306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   421 IAETKRQMHETLEMKEEEIAQLRSRI-------KQMTTQGEELREQKE------KSERAAFEELEKALSTAQKTEEARRK 487
Cdd:TIGR02168  307 LRERLANLERQLEELEAQLEELESKLdelaeelAELEEKLEELKEELEsleaelEELEAELEELESRLEELEEQLETLRS 386

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   488 LKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEkELARKEQELtKKLQTREREFQEQMK 567
Cdd:TIGR02168  387 KVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQA-ELEELEEEL-EELQEELERLEEALE 464

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   568 VAL----EKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILEL-------ESSLEKSLQ 636
Cdd:TIGR02168  465 ELReeleEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELisvdegyEAAIEAALG 544

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   637 EN-------KNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLK------------------- 690
Cdd:TIGR02168  545 GRlqavvveNLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKdlvkfdpklrkalsyllgg 624

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   691 ----QQYQTEMEKLREKCEQE-----KETLLKDKEIIFQAHiEEMNEKTLEK---LDVKQTELESLSSELSEVLKARHKL 758
Cdd:TIGR02168  625 vlvvDDLDNALELAKKLRPGYrivtlDGDLVRPGGVITGGS-AKTNSSILERrreIEELEEKIEELEEKIAELEKALAEL 703

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   759 EEELSVLKDQTDKMKQELEAKMDEQKNHHQQ--QVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDK---HLKEHQAH 833
Cdd:TIGR02168  704 RKELEELEEELEQLRKELEELSRQISALRKDlaRLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEaeeELAEAEAE 783

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   834 VENLEADIKRSEGELQQASAKLDVFQSYQSATHE-----QTKAYEEQLAQLQQKLLDLETERIL--LTKQVAEVEAQKKD 906
Cdd:TIGR02168  784 IEELEAQIEQLKEELKALREALDELRAELTLLNEeaanlRERLESLERRIAATERRLEDLEEQIeeLSEDIESLAAEIEE 863

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   907 VCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVyESKLEDGNKEQEQTKQILVEKENMILQMREgqkkEIEILTQKL 986
Cdd:TIGR02168  864 LEELIEELESELEALLNERASLEEALALLRSELEEL-SEELRELESKRSELRRELEELREKLAQLEL----RLEGLEVRI 938

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|.
gi 530372322   987 SAKEDSihiLNEEYETKFKNQEKKMEKVKQKAKEMQETLKK 1027
Cdd:TIGR02168  939 DNLQER---LSEEYSLTLEEAEALENKIEDDEEEARRRLKR 976
PTZ00121 PTZ00121
MAEBL; Provisional
 440-1179 3.48e-11

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 69.40  E-value: 3.48e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  440 AQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERiSLQQELSRVKQ 519
Cdd:PTZ00121 1083 AKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAED-AKRVEIARKAE 1161

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  520 EVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREfqEQMKVALEKSQSEYLKisQEKEQQESLALEELELQK 599
Cdd:PTZ00121 1162 DARKAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAE--AARKAEEERKAEEARK--AEDAKKAEAVKKAEEAKK 1237

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  600 KAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAvhlEAEKNKHNKEITVMVEKHKTElESLKHQQD 679
Cdd:PTZ00121 1238 DAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELK---KAEEKKKADEAKKAEEKKKAD-EAKKKAEE 1313

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  680 ALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLE 759
Cdd:PTZ00121 1314 AKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKA 1393

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  760 EELSVLKDQTDKMKQELEAKMDEQK--NHHQQQVDSIIKEHEVSIQRTEKALKDQInqlelllkeRDKHLKEHQAHVENL 837
Cdd:PTZ00121 1394 DEAKKKAEEDKKKADELKKAAAAKKkaDEAKKKAEEKKKADEAKKKAEEAKKADEA---------KKKAEEAKKAEEAKK 1464

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  838 EADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEV----EAQKKDVCTELDA 913
Cdd:PTZ00121 1465 KAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAkkaeEAKKADEAKKAEE 1544

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  914 HKiQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSI 993
Cdd:PTZ00121 1545 KK-KADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAE 1623

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  994 HILNEEYETKFKNQ-EKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDA 1072
Cdd:PTZ00121 1624 ELKKAEEEKKKVEQlKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKK 1703

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1073 VSRLETNQKEQIESLTEVHRRElnDVISIWEKKLNQQAEELQEIHEiQLQEKEQEVAELKQKILLFGCEKEEMNKEITWL 1152
Cdd:PTZ00121 1704 AEELKKKEAEEKKKAEELKKAE--EENKIKAEEAKKEAEEDKKKAE-EAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAV 1780

                         730       740
                  ....*....|....*....|....*..
gi 530372322 1153 KEEGVKQDTTLNELQEQLKQKSAHVNS 1179
Cdd:PTZ00121 1781 IEEELDEEDEKRRMEVDKKIKDIFDNF 1807
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1502-2141 4.43e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 68.42  E-value: 4.43e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1502 KKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDclkgEMEDDKSKMEKKESNLETELKSQTAR 1581
Cdd:COG1196   235 RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELE----EAQAEEYELLAELARLEQDIARLEER 310

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1582 IMELEDHITQKTIEIESLNEVLKNYNQQKD---IEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELET 1658
Cdd:COG1196   311 RRELEERLEELEEELAELEEELEELEEELEeleEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLE 390

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1659 KKKELehvnLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQykkgteSHLSELNTKLQE 1738
Cdd:COG1196   391 ALRAA----AELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAA------EEEAELEEEEEA 460

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1739 REREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQRVGQEKEETV 1818
Cdd:COG1196   461 LLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAAL 540

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1819 SSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGH---LQEELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENVFDDVQK 1895
Cdd:COG1196   541 EAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRatfLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGD 620

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1896 TLQEKELTCQILEQKIKELDSCLVRQKEVhRVEMEELtskyeklqalqqmdgrnkptelleenteekskshlvqpkllsn 1975
Cdd:COG1196   621 TLLGRTLVAARLEAALRRAVTLAGRLREV-TLEGEGG------------------------------------------- 656

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1976 meaqhNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMRE 2055
Cdd:COG1196   657 -----SAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLE 731

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 2056 FNTQLAQKEQELEMTIKETINKAQEVEAELLESHQEETNQLLKKIAEK-------DDDLKRTAKRYEEildareeeMTAK 2128
Cdd:COG1196   732 AEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALgpvnllaIEEYEELEERYDF--------LSEQ 803

                         650
                  ....*....|...
gi 530372322 2129 VRDLQTQLEELQK 2141
Cdd:COG1196   804 REDLEEARETLEE 816
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 758-1081 5.34e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 68.42  E-value: 5.34e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  758 LEEELSVLKDQTDKMK--QELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVE 835
Cdd:COG1196   198 LERQLEPLERQAEKAEryRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELE 277

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  836 NLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHK 915
Cdd:COG1196   278 ELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAE 357

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  916 IQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVekenmILQMREGQKKEIEILTQKLSAKEDSIHI 995
Cdd:COG1196   358 AELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEE-----LEEAEEALLERLERLEEELEELEEALAE 432

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  996 LNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSR 1075
Cdd:COG1196   433 LEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKA 512


                  ....*.
gi 530372322 1076 LETNQK 1081
Cdd:COG1196   513 ALLLAG 518
PTZ00121 PTZ00121
MAEBL; Provisional
 1445-1913 6.93e-11

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 68.24  E-value: 6.93e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1445 SEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQiQLEL 1524
Cdd:PTZ00121 1286 AEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAE-AAEE 1364

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1525 KSKEAYEKDEQINLLKEELD---QQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARimeledhitqktieiESLNE 1601
Cdd:PTZ00121 1365 KAEAAEKKKEEAKKKADAAKkkaEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAK---------------KKAEE 1429

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1602 VLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQvysMKAELETKKKELEHVNLSVKSKEEELKALE 1681
Cdd:PTZ00121 1430 KKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAK---KKAEEAKKADEAKKKAEEAKKKADEAKKAA 1506

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1682 DRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETL 1761
Cdd:PTZ00121 1507 EAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEA 1586

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1762 --IVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQ-RNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHA 1838
Cdd:PTZ00121 1587 kkAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEElKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEE 1666

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 530372322 1839 EAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKE 1913
Cdd:PTZ00121 1667 AKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEE 1741
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 370-1237 4.11e-09

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 62.30  E-value: 4.11e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   370 EKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETkrqmheTLEMKEEEIAQLRSRIKQM 449
Cdd:pfam02463  171 KKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEY------LLYLDYLKLNEERIDLLQE 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   450 TTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSS 529
Cdd:pfam02463  245 LLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKK 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   530 EEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKS--QSEYLKISQEKEQQESLALEELELQKKAILTESE 607
Cdd:pfam02463  325 KAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLeqLEEELLAKKKLESERLSSAAKLKEEELELKSEEE 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   608 NKLRDLQQEAETYRTRILELESSLEKSLQENKnqskdLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQ 687
Cdd:pfam02463  405 KEAQLLLELARQLEDLLKEEKKEELEILEEEE-----ESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQL 479

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   688 VLKQQYQTEMEKLREkcEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKD 767
Cdd:pfam02463  480 VKLQEQLELLLSRQK--LEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATA 557

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   768 QTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGE 847
Cdd:pfam02463  558 DEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKL 637

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   848 LQQASAKLDVFQSYQSATHEQTkayEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEK 927
Cdd:pfam02463  638 KESAKAKESGLRKGVSLEEGLA---EKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKK 714

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   928 QNSEMEQKVKSLTQVYESKL-EDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKN 1006
Cdd:pfam02463  715 LKLEAEELLADRVQEAQDKInEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEE 794

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1007 QEKKMEKVKQKAKEmqetlKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIES 1086
Cdd:pfam02463  795 KLKAQEEELRALEE-----ELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELL 869

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1087 LTEVHRRELNDVISIWEKKLNQQAEELQEIHE-IQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNE 1165
Cdd:pfam02463  870 QELLLKEEELEEQKLKDELESKEEKEKEEKKElEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKE 949

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 530372322  1166 LQEQLKQKSAHVNSLAQDEtklKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTD 1237
Cdd:pfam02463  950 KEENNKEEEEERNKRLLLA---KEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQR 1018
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 354-673 8.63e-09

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 60.91  E-value: 8.63e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   354 KETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQ----LEQDKGMVIAETKRQMH 429
Cdd:pfam17380  281 QKAVSERQQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQermaMERERELERIRQEERKR 360

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   430 ETLEMKEEEIAQLRSRIKQMttqgEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEqiktIEKTSEEERIS 509
Cdd:pfam17380  361 ELERIRQEEIAMEISRMREL----ERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQKVE----MEQIRAEQEEA 432

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   510 LQQELSRVKQEVVDVMKKSSEEQIAK---LQKLHEKELARKEQELTKKLQTRER-EFQEQMKVALEKSQSEYLKISQEKE 585
Cdd:pfam17380  433 RQREVRRLEEERAREMERVRLEEQERqqqVERLRQQEEERKRKKLELEKEKRDRkRAEEQRRKILEKELEERKQAMIEEE 512

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   586 QQESLALEELELQKKAILTESEnklrdlQQEAETYRTRILELESslEKSLQENKNQSKDLAVHLEA-EKNKHNKEITVMV 664
Cdd:pfam17380  513 RKRKLLEKEMEERQKAIYEEER------RREAEEERRKQQEMEE--RRRIQEQMRKATEERSRLEAmEREREMMRQIVES 584


                   ....*....
gi 530372322   665 EKHKTELES 673
Cdd:pfam17380  585 EKARAEYEA 593
Grip smart00755
golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;
2220-2263 5.55e-08

golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;


Pssm-ID: 197860  Cd Length: 46  Bit Score: 50.68  E-value: 5.55e-08
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*.
gi 530372322   2220 PTEFEYLRKVLFEYMMGRET--KTMAKVITTVLKFPDDQTQKILER 2263
Cdd:smart00755    1 EANFEYLKNVLLQFLTLRESerETLLPVISTVLQLSPEEMQKLLEV 46
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 191-507 1.32e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 53.92  E-value: 1.32e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   191 KEQLIQRLRRMERSLSSYRGKYSElvtAYQMLqREKKKLQGILSQSQDKSLRRIAELREELQMDQQ---AKKHLQEEFDA 267
Cdd:TIGR02169  690 LSSLQSELRRIENRLDELSQELSD---ASRKI-GEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQeieNVKSELKELEA 765

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   268 SLEEKDQYISVLQTQVSLLKQRLRNGPMNV------DVLKPLPQLEPQAEVFTKEENPESDGEPVVEDgtSVKTLETLQQ 341
Cdd:TIGR02169  766 RIEELEEDLHKLEEALNDLEARLSHSRIPEiqaelsKLEEEVSRIEARLREIEQKLNRLTLEKEYLEK--EIQELQEQRI 843

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   342 RVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGmvi 421
Cdd:TIGR02169  844 DLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLS--- 920

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   422 aetkrQMHETLEMKEEEIAQLRSRIKQMTTQGEE------LREQKEKSERA----------AFEELEKALSTAQKTEEAR 485
Cdd:TIGR02169  921 -----ELKAKLEALEEELSEIEDPKGEDEEIPEEelsledVQAELQRVEEEiralepvnmlAIQEYEEVLKRLDELKEKR 995

                          330       340
                   ....*....|....*....|..
gi 530372322   486 RKLKAEMDEQIKTIEKTSEEER 507
Cdd:TIGR02169  996 AKLEEERKAILERIEEYEKKKR 1017
mukB PRK04863
chromosome partition protein MukB;
192-459 2.98e-06

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 53.04  E-value: 2.98e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  192 EQLIQRLRRMERSLSSYRGKYSELVTAYQMLQREKKKLQGILSQS---QDKSL-RRIAELREELQMDQQAKKHLQ----- 262
Cdd:PRK04863  840 RQLNRRRVELERALADHESQEQQQRSQLEQAKEGLSALNRLLPRLnllADETLaDRVEEIREQLDEAEEAKRFVQqhgna 919

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  263 ----EEFDASLEEKDQYISVLQTQVSLLKQRLRNGPMNVDVLKPLPQlepQAEVFTKEENPESDGEpvvEDGTSvktlET 338
Cdd:PRK04863  920 laqlEPIVSVLQSDPEQFEQLKQDYQQAQQTQRDAKQQAFALTEVVQ---RRAHFSYEDAAEMLAK---NSDLN----EK 989

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  339 LQQRVKRQENLLKRCKETIQSHKEQCTL-------LTSEKEALQEQLDERLQELEKI--------KDLHMAEKTKLITQL 403
Cdd:PRK04863  990 LRQRLEQAEQERTRAREQLRQAQAQLAQynqvlasLKSSYDAKRQMLQELKQELQDLgvpadsgaEERARARRDELHARL 1069

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 530372322  404 RDAKNLIEQLEQdkgmviaetkrqmheTLEMKEEEIAQLRSRIKQMTTQGEELREQ 459
Cdd:PRK04863 1070 SANRSRRNQLEK---------------QLTFCEAEMDNLTKKLRKLERDYHEMREQ 1110
GRIP pfam01465
GRIP domain; The GRIP (golgin-97, RanBP2alpha,Imh1p and p230/golgin-245) domain is found in ...
 2221-2260 1.23e-05

GRIP domain; The GRIP (golgin-97, RanBP2alpha,Imh1p and p230/golgin-245) domain is found in many large coiled-coil proteins. It has been shown to be sufficient for targeting to the Golgi. The GRIP domain contains a completely conserved tyrosine residue. At least some of these domains have been shown to bind to GTPase Arl1, see structures in.


Pssm-ID: 460221 [Multi-domain]  Cd Length: 44  Bit Score: 44.27  E-value: 1.23e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|...
gi 530372322  2221 TEFEYLRKVLFEYMMGRET---KTMAKVITTVLKFPDDQTQKI 2260
Cdd:pfam01465    2 ANLEYLKNVLLQFLESKESserKQLLPVIATLLKFSPEEEQKI 44
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1516-2185 1.59e-05

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 50.36  E-value: 1.59e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1516 KELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIE 1595
Cdd:pfam02463  207 KKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEE 286

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1596 IESLNEVLKNYNQQKDIehkelvqKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEE 1675
Cdd:pfam02463  287 ELKLLAKEEEELKSELL-------KLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEE 359

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1676 ELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQykkgteshlSELNTKLQEREREVHILEEKLKSVES 1755
Cdd:pfam02463  360 ELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEE---------KEAQLLLELARQLEDLLKEEKKEELE 430

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1756 SQSETLIVPRSAKNVAAyTEQEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKL 1835
Cdd:pfam02463  431 ILEEEEESIELKQGKLT-EEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGL 509

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1836 EHAEAkqhedQSMIGHLQEELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKELD 1915
Cdd:pfam02463  510 KVLLA-----LIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLI 584

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1916 SCLVRQKEVHRVEMEELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQ 1995
Cdd:pfam02463  585 PKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEV 664

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1996 KLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIKETI 2075
Cdd:pfam02463  665 KASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQK 744

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  2076 NKAQEVEAELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEENPGN 2155
Cdd:pfam02463  745 IDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLI 824

                          650       660       670
                   ....*....|....*....|....*....|
gi 530372322  2156 DNTQLAQKTTLISDSKLKEQEFREQIHNLE 2185
Cdd:pfam02463  825 EQEEKIKEEELEELALELKEEQKLEKLAEE 854
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
172-459 1.24e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 47.60  E-value: 1.24e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  172 PSDMDSEAEDLVGNSDSLNK-EQLIQRLRRMERSLS---SYRGKYSELVTAYQMLQREKKKLQGILSQSQDKSLR-RIAE 246
Cdd:COG4913   220 EPDTFEAADALVEHFDDLERaHEALEDAREQIELLEpirELAERYAAARERLAELEYLRAALRLWFAQRRLELLEaELEE 299

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  247 LREELQMDQQAKKHLQEEFDASLEEKDQyisvlqtqvsLLKQRLRNGpmnVDVLKPLPQLEPQAEvftkeenpesdgepv 326
Cdd:COG4913   300 LRAELARLEAELERLEARLDALREELDE----------LEAQIRGNG---GDRLEQLEREIERLE--------------- 351

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  327 vedgtsvKTLETLQQRVKRQENLLKRCKETIQSHKEqctlltsEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDA 406
Cdd:COG4913   352 -------RELEERERRRARLEALLAALGLPLPASAE-------EFAALRAEAAALLEALEEELEALEEALAEAEAALRDL 417

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|...
gi 530372322  407 KNLIEQLEQdkgmviaetkrqmhetlemkeeEIAQLRSRIKQMTTQGEELREQ 459
Cdd:COG4913   418 RRELRELEA----------------------EIASLERRKSNIPARLLALRDA 448
 
Name Accession Description Interval E-value
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1501-2142 1.21e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 80.49  E-value: 1.21e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1501 KKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRfdclKGEMEDDKSKMEKKESNLETELKSQTA 1580
Cdd:TIGR02168  248 LKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANE----ISRLEQQKQILRERLANLERQLEELEA 323

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1581 RIMELEDHITQKTIEIESLN---EVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELE 1657
Cdd:TIGR02168  324 QLEELESKLDELAEELAELEeklEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEIE 403

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1658 TKKKELEHVNLSVKSKEEELKALEDRLESesaAKLAELKRKAEQKIAAIKKqLLSQMEEKEEQYKKGTEShLSELNTKLQ 1737
Cdd:TIGR02168  404 RLEARLERLEDRRERLQQEIEELLKKLEE---AELKELQAELEELEEELEE-LQEELERLEEALEELREE-LEEAEQALD 478

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1738 EREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQeEADSQGC------VQKTYEEKIS---------VLQRNLTE 1802
Cdd:TIGR02168  479 AAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSG-LSGILGVlselisVDEGYEAAIEaalggrlqaVVVENLNA 557

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1803 KEKLLQrvGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHED--------------------QSMIGH------LQEEL 1856
Cdd:TIGR02168  558 AKKAIA--FLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEgflgvakdlvkfdpklrkalSYLLGGvlvvddLDNAL 635

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1857 EEKNKKYS----------LIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKELdsclvrQKEVHR 1926
Cdd:TIGR02168  636 ELAKKLRPgyrivtldgdLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAEL------RKELEE 709

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1927 VEMEELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQK 2006
Cdd:TIGR02168  710 LEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEA 789

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  2007 DLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIkETINKAQEVEAELL 2086
Cdd:TIGR02168  790 QIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDI-ESLAAEIEELEELI 868

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 530372322  2087 ESHQEETNQLLKKIAEKDDDLKRTAKRYEEiLDAREEEMTAKVRDLQTQLEELQKK 2142
Cdd:TIGR02168  869 EELESELEALLNERASLEEALALLRSELEE-LSEELRELESKRSELRRELEELREK 923
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 796-1720 2.99e-14

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 78.95  E-value: 2.99e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   796 KEHEVSIQRTEKALKdqinQLELLLKERDKHLKEHQAHVENLEA--DIKRSEGELQQASAKLDV--FQSYQSATHEQTKA 871
Cdd:TIGR02168  175 KETERKLERTRENLD----RLEDILNELERQLKSLERQAEKAERykELKAELRELELALLVLRLeeLREELEELQEELKE 250

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   872 YEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGN 951
Cdd:TIGR02168  251 AEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELES 330

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   952 KEQEQTKqilvekenmILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQEtlkkklld 1031
Cdd:TIGR02168  331 KLDELAE---------ELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLEL-------- 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1032 QEAKLKKELENTALELSQkekqfnakmlemaqansagISDAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAE 1111
Cdd:TIGR02168  394 QIASLNNEIERLEARLER-------------------LEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQE 454

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1112 ELqEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEegvkqdttlneLQEQLKQKSAHVNSLAQDETKLKAHL 1191
Cdd:TIGR02168  455 EL-ERLEEALEELREELEEAEQALDAAERELAQLQARLDSLER-----------LQENLEGFSEGVKALLKNQSGLSGIL 522

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1192 ----EKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEE 1267
Cdd:TIGR02168  523 gvlsELISVDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLG 602

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1268 LAIQLDICCKKTEALLeaktnelinisssktNAILSRISHCQhrttkvkealliktctvseleaqlrqlteeqntlniSF 1347
Cdd:TIGR02168  603 VAKDLVKFDPKLRKAL---------------SYLLGGVLVVD------------------------------------DL 631

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1348 QQATHQLEEKENQiksmkadiESLVTEKEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSL 1427
Cdd:TIGR02168  632 DNALELAKKLRPG--------YRIVTLDGDLVRPGGVITGGSAKTNSSILERRREIEELEEKIEELEEKIAELEKALAEL 703

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1428 SKQLTDLNVQL-QNSISLSEKEAAISSLRKQYDEEKCE---LLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKK 1503
Cdd:TIGR02168  704 RKELEELEEELeQLRKELEELSRQISALRKDLARLEAEveqLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAE 783

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1504 AQSRftqhQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEkkesNLETELKSQTARIM 1583
Cdd:TIGR02168  784 IEEL----EAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLE----DLEEQIEELSEDIE 855

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1584 ELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGE---EKDNRVKEAEEKILTLENQVYSMKAELETKK 1660
Cdd:TIGR02168  856 SLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEelrELESKRSELRRELEELREKLAQLELRLEGLE 935

                          890       900       910       920       930       940
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 530372322  1661 KELEHVNLSVKSK----EEELKALEDRLESESAAKLAELKRkAEQKIAAIKKQLLSQMEEKEEQ 1720
Cdd:TIGR02168  936 VRIDNLQERLSEEysltLEEAEALENKIEDDEEEARRRLKR-LENKIKELGPVNLAAIEEYEEL 998
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 976-1823 1.34e-13

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 77.03  E-value: 1.34e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   976 KKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEK------VKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQ 1049
Cdd:TIGR02169  183 EENIERLDLIIDEKRQQLERLRREREKAERYQALLKEKreyegyELLKEKEALERQKEAIERQLASLEEELEKLTEEISE 262

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1050 KEKQFNAKMLEMAQANsAGISDAVSRLETNQKEQIESLtEVHRRELNDVISIWEKKLNQQAEELQEIhEIQLQEKEQEVA 1129
Cdd:TIGR02169  263 LEKRLEEIEQLLEELN-KKIKDLGEEEQLRVKEKIGEL-EAEIASLERSIAEKERELEDAEERLAKL-EAEIDKLLAEIE 339

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1130 ELKQKIllfgcekEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQ 1209
Cdd:TIGR02169  340 ELEREI-------EEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQ 412

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1210 EQLVELKMLAEEDKRKVSELTSKLKTTDEEfqslkssheksnksLEDKSLEFKKLSEELaiqldiccKKTEALLEAKTNE 1289
Cdd:TIGR02169  413 EELQRLSEELADLNAAIAGIEAKINELEEE--------------KEDKALEIKKQEWKL--------EQLAADLSKYEQE 470

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1290 LINISSsKTNAILSRISHCQHRttkvkealliktctVSELEAQLRQLTEEQntlnISFQQAThqlEEKENQIKSMKADIE 1369
Cdd:TIGR02169  471 LYDLKE-EYDRVEKELSKLQRE--------------LAEAEAQARASEERV----RGGRAVE---EVLKASIQGVHGTVA 528

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1370 SLVTEKE----ALQKEGGNQQQAA-----SEKESCITQLKkelSENINAVTLMKEELKEKKVEISSLSKQ---------L 1431
Cdd:TIGR02169  529 QLGSVGEryatAIEVAAGNRLNNVvveddAVAKEAIELLK---RRKAGRATFLPLNKMRDERRDLSILSEdgvigfavdL 605

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1432 TDLNVQLQNSIS------------------------------LSEKEAAI---SSLRKQYDEEKCELLDQVQDLSFKVDT 1478
Cdd:TIGR02169  606 VEFDPKYEPAFKyvfgdtlvvedieaarrlmgkyrmvtlegeLFEKSGAMtggSRAPRGGILFSRSEPAELQRLRERLEG 685

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1479 LSKEKISALEQVDdwsnkfsewkkKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEME 1558
Cdd:TIGR02169  686 LKRELSSLQSELR-----------RIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIE 754

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1559 DDKSKM---EKKESNLETELKSQTARIMELEDHITQKTI-EIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNR 1634
Cdd:TIGR02169  755 NVKSELkelEARIEELEEDLHKLEEALNDLEARLSHSRIpEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKE 834

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1635 VKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLEsesaaKLAELKRKAEQKIAAIKKQLlsqm 1714
Cdd:TIGR02169  835 IQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLG-----DLKKERDELEAQLRELERKI---- 905

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1715 EEKEEQYKKgTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQ------------EEADSQ 1782
Cdd:TIGR02169  906 EELEAQIEK-KRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQAELQRVEEEiralepvnmlaiQEYEEV 984

                          890       900       910       920
                   ....*....|....*....|....*....|....*....|.
gi 530372322  1783 GCVQKTYEEKISVLQRNLTEKEKLLQRVGQEKEETVSSHFE 1823
Cdd:TIGR02169  985 LKRLDELKEKRAKLEEERKAILERIEEYEKKKREVFMEAFE 1025
PTZ00121 PTZ00121
MAEBL; Provisional
 370-1052 3.90e-13

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 75.56  E-value: 3.90e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  370 EKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAknlieqlEQDKGMVIAetkRQMHETLEMKEEEIAQLRSRIKQm 449
Cdd:PTZ00121 1112 EEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKA-------EDAKRVEIA---RKAEDARKAEEARKAEDAKKAEA- 1180

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  450 TTQGEELREQKE--KSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDvMKK 527
Cdd:PTZ00121 1181 ARKAEEVRKAEElrKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRK-FEE 1259

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  528 SSEEQIAKLQKLHEKELARKEQELTKKLQTRErefQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKK---AILT 604
Cdd:PTZ00121 1260 ARMAHFARRQAAIKAEEARKADELKKAEEKKK---ADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKkadAAKK 1336

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  605 ESENKLRDLQQEAETYRTRILELESSLEKS----LQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDA 680
Cdd:PTZ00121 1337 KAEEAKKAAEAAKAEAEAAADEAEAAEEKAeaaeKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADELKKAAAA 1416

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  681 LWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLE--KLDVKQTELESLSSELSEVLKARHKL 758
Cdd:PTZ00121 1417 KKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEakKADEAKKKAEEAKKADEAKKKAEEAK 1496

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  759 EEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLE 838
Cdd:PTZ00121 1497 KKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDK 1576

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  839 ADIKRSEGELQQASAKldvfqsyqsATHEQTKAYEEQLAQLQQKLLDLETERILLTK-QVAEVEAQKKDVCTELDAHKIQ 917
Cdd:PTZ00121 1577 NMALRKAEEAKKAEEA---------RIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEElKKAEEEKKKVEQLKKKEAEEKK 1647

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  918 VQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQilveKENMILQMREGQKKEIEILTQKLSAKEDSIHILN 997
Cdd:PTZ00121 1648 KAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKK----AAEALKKEAEEAKKAEELKKKEAEEKKKAEELKK 1723

                         650       660       670       680       690
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 530372322  998 EEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEK 1052
Cdd:PTZ00121 1724 AEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKE 1778
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1326-2139 1.35e-12

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 73.55  E-value: 1.35e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1326 VSELEAQLRQLtEEQNTLNISFQQATHQLEEKenQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLKKELSE 1405
Cdd:TIGR02168  195 LNELERQLKSL-ERQAEKAERYKELKAELREL--ELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEE 271

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1406 NINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQnsiSLSEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKIS 1485
Cdd:TIGR02168  272 LRLEVSELEEEIEELQKELYALANEISRLEQQKQ---ILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEE 348

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1486 ALEQVDDWSNKFSEWKKKAQSRftqhQNTVKELQIQLELKSKEAYEKDEQINLLKEELdqqnkrfdclkGEMEDDKSKME 1565
Cdd:TIGR02168  349 LKEELESLEAELEELEAELEEL----ESRLEELEEQLETLRSKVAQLELQIASLNNEI-----------ERLEARLERLE 413

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1566 KKESNLETELKSQTARIMELEDHITQKTIEieslnevlknynqQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTL 1645
Cdd:TIGR02168  414 DRRERLQQEIEELLKKLEEAELKELQAELE-------------ELEEELEELQEELERLEEALEELREELEEAEQALDAA 480

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1646 ENQVYSMKAELETkkkelehvnlsvkskeeeLKALEDRLESESAAKLAELKrkaEQKIAAIKKQLLSQMEEKEEQYKKGT 1725
Cdd:TIGR02168  481 ERELAQLQARLDS------------------LERLQENLEGFSEGVKALLK---NQSGLSGILGVLSELISVDEGYEAAI 539

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1726 ESHLSE-LNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQR------ 1798
Cdd:TIGR02168  540 EAALGGrLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKlrkals 619

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1799 ----------------NLTEKEKLLQRVGQEKEETVSSHF-------EMRCQYQERLIKLEHAEAKQHEDQSMIGHLQEE 1855
Cdd:TIGR02168  620 yllggvlvvddldnalELAKKLRPGYRIVTLDGDLVRPGGvitggsaKTNSSILERRREIEELEEKIEELEEKIAELEKA 699

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1856 LEEKNKKYSLIVAQHVEKEggknniQAKQNLENVFDDVQKTLQEKELTCQILEQKIKELDSCLVRQKEVHRVEMEELTSK 1935
Cdd:TIGR02168  700 LAELRKELEELEEELEQLR------KELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEA 773

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1936 YEKLQALQQMDGRNKPTELLEENTEEKSKSHLvqpkllSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEH 2015
Cdd:TIGR02168  774 EEELAEAEAEIEELEAQIEQLKEELKALREAL------DELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQI 847

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  2016 QQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLESHQE---- 2091
Cdd:TIGR02168  848 EELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKlaql 927

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 530372322  2092 ---------ETNQLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQLEEL 2139
Cdd:TIGR02168  928 elrleglevRIDNLQERLSEEYSLTLEEAEALENKIEDDEEEARRRLKRLENKIKEL 984
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 334-856 5.58e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 71.51  E-value: 5.58e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  334 KTLETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDE----------RLQELEKIKDLHMAEKTKLITQL 403
Cdd:COG1196   239 AELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEaqaeeyellaELARLEQDIARLEERRRELEERL 318

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  404 RDAKNLIEQLEQDKGMVIAETKRQmHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEE 483
Cdd:COG1196   319 EELEEELAELEEELEELEEELEEL-EEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAE 397

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  484 ARRKLK--AEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTRERE 561
Cdd:COG1196   398 LAAQLEelEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEA 477

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  562 FQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQ 641
Cdd:COG1196   478 ALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDE 557

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  642 SKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQA 721
Cdd:COG1196   558 VAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALR 637

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  722 HIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVS 801
Cdd:COG1196   638 RAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERL 717

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 530372322  802 IQRTEKALKDQinQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLD 856
Cdd:COG1196   718 EEELEEEALEE--QLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELE 770
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 336-620 8.51e-12

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 71.12  E-value: 8.51e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  336 LETLQQRVKRQENLLKRCKETIQSHKEQctllTSEKEALQEQLDERLQELEKikdlhmaEKTKLITQLRDAKNLIEQLEQ 415
Cdd:COG1196   234 LRELEAELEELEAELEELEAELEELEAE----LAELEAELEELRLELEELEL-------ELEEAQAEEYELLAELARLEQ 302

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  416 DKgMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSEraafEELEKALSTAQKTEEARRKLKAEMDEQ 495
Cdd:COG1196   303 DI-ARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAE----EELEEAEAELAEAEEALLEAEAELAEA 377

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  496 IKTIEKTSEEERISLQQELSRVKQ-EVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQ 574
Cdd:COG1196   378 EEELEELAEELLEALRAAAELAAQlEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEE 457

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 530372322  575 SEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETY 620
Cdd:COG1196   458 EEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADY 503
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 602-1371 1.62e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 70.09  E-value: 1.62e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   602 ILTESENKLRDLQQEAET---YRtRILELESSLEKSLQENKNQSkdlavhLEAEKNKHNKEITVMVEKHKtELESLKHQQ 678
Cdd:TIGR02168  194 ILNELERQLKSLERQAEKaerYK-ELKAELRELELALLVLRLEE------LREELEELQEELKEAEEELE-ELTAELQEL 265

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   679 DALWTEKlqvlkqqyQTEMEKLREKCEQEKETLLKDKEIIfqAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKL 758
Cdd:TIGR02168  266 EEKLEEL--------RLEVSELEEEIEELQKELYALANEI--SRLEQQKQILRERLANLERQLEELEAQLEELESKLDEL 335

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   759 EEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSiikehevsiQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLE 838
Cdd:TIGR02168  336 AEELAELEEKLEELKEELESLEAELEELEAELEEL---------ESRLEELEEQLETLRSKVAQLELQIASLNNEIERLE 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   839 ADIKRSEGELQQASakldvfqsyQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKdvctELDAHKIQV 918
Cdd:TIGR02168  407 ARLERLEDRRERLQ---------QEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALE----ELREELEEA 473

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   919 QDLMQQLEKQNSEMEQKVKSLtqvyESKLEDGNKEQEQTKQILVEKENM---------ILQMREGQKKEIE--------- 980
Cdd:TIGR02168  474 EQALDAAERELAQLQARLDSL----ERLQENLEGFSEGVKALLKNQSGLsgilgvlseLISVDEGYEAAIEaalggrlqa 549

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   981 ILTQKLSAKEDSIHILNEEYETK-----------FKNQEKKMEKVKQKAKEMQetLKKKLLDQEAKLKKELEN------- 1042
Cdd:TIGR02168  550 VVVENLNAAKKAIAFLKQNELGRvtflpldsikgTEIQGNDREILKNIEGFLG--VAKDLVKFDPKLRKALSYllggvlv 627

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1043 -----TALELSQKEK-QFNAKMLEMAQANSAGISdavsrleTNQKEQIESLTEVHRRELNDVisiwEKKLNQQAEELQEI 1116
Cdd:TIGR02168  628 vddldNALELAKKLRpGYRIVTLDGDLVRPGGVI-------TGGSAKTNSSILERRREIEEL----EEKIEELEEKIAEL 696

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1117 hEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEV 1196
Cdd:TIGR02168  697 -EKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEE 775

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1197 DLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEElaiqldicc 1276
Cdd:TIGR02168  776 ELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQ--------- 846

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1277 KKTEALLEAKTNELINISSSKTNAILSRISHCQHRTTKVKEALliktctvSELEAQLRQLTEEQNTLNISFQQATHQLEE 1356
Cdd:TIGR02168  847 IEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEAL-------ALLRSELEELSEELRELESKRSELRRELEE 919

                          810
                   ....*....|....*
gi 530372322  1357 KENQIKSMKADIESL 1371
Cdd:TIGR02168  920 LREKLAQLELRLEGL 934
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 342-1027 1.84e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 70.09  E-value: 1.84e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   342 RVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDE-RLQELEKIKDLHMAEKTklitqLRDAKNLIEQLEQDKgMV 420
Cdd:TIGR02168  233 RLEELREELEELQEELKEAEEELEELTAELQELEEKLEElRLEVSELEEEIEELQKE-----LYALANEISRLEQQK-QI 306

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   421 IAETKRQMHETLEMKEEEIAQLRSRI-------KQMTTQGEELREQKE------KSERAAFEELEKALSTAQKTEEARRK 487
Cdd:TIGR02168  307 LRERLANLERQLEELEAQLEELESKLdelaeelAELEEKLEELKEELEsleaelEELEAELEELESRLEELEEQLETLRS 386

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   488 LKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEkELARKEQELtKKLQTREREFQEQMK 567
Cdd:TIGR02168  387 KVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQA-ELEELEEEL-EELQEELERLEEALE 464

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   568 VAL----EKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILEL-------ESSLEKSLQ 636
Cdd:TIGR02168  465 ELReeleEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELisvdegyEAAIEAALG 544

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   637 EN-------KNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLK------------------- 690
Cdd:TIGR02168  545 GRlqavvveNLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKdlvkfdpklrkalsyllgg 624

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   691 ----QQYQTEMEKLREKCEQE-----KETLLKDKEIIFQAHiEEMNEKTLEK---LDVKQTELESLSSELSEVLKARHKL 758
Cdd:TIGR02168  625 vlvvDDLDNALELAKKLRPGYrivtlDGDLVRPGGVITGGS-AKTNSSILERrreIEELEEKIEELEEKIAELEKALAEL 703

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   759 EEELSVLKDQTDKMKQELEAKMDEQKNHHQQ--QVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDK---HLKEHQAH 833
Cdd:TIGR02168  704 RKELEELEEELEQLRKELEELSRQISALRKDlaRLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEaeeELAEAEAE 783

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   834 VENLEADIKRSEGELQQASAKLDVFQSYQSATHE-----QTKAYEEQLAQLQQKLLDLETERIL--LTKQVAEVEAQKKD 906
Cdd:TIGR02168  784 IEELEAQIEQLKEELKALREALDELRAELTLLNEeaanlRERLESLERRIAATERRLEDLEEQIeeLSEDIESLAAEIEE 863

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   907 VCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVyESKLEDGNKEQEQTKQILVEKENMILQMREgqkkEIEILTQKL 986
Cdd:TIGR02168  864 LEELIEELESELEALLNERASLEEALALLRSELEEL-SEELRELESKRSELRRELEELREKLAQLEL----RLEGLEVRI 938

                          730       740       750       760
                   ....*....|....*....|....*....|....*....|.
gi 530372322   987 SAKEDSihiLNEEYETKFKNQEKKMEKVKQKAKEMQETLKK 1027
Cdd:TIGR02168  939 DNLQER---LSEEYSLTLEEAEALENKIEDDEEEARRRLKR 976
PTZ00121 PTZ00121
MAEBL; Provisional
 440-1179 3.48e-11

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 69.40  E-value: 3.48e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  440 AQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERiSLQQELSRVKQ 519
Cdd:PTZ00121 1083 AKEDNRADEATEEAFGKAEEAKKTETGKAEEARKAEEAKKKAEDARKAEEARKAEDARKAEEARKAED-AKRVEIARKAE 1161

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  520 EVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREfqEQMKVALEKSQSEYLKisQEKEQQESLALEELELQK 599
Cdd:PTZ00121 1162 DARKAEEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAE--AARKAEEERKAEEARK--AEDAKKAEAVKKAEEAKK 1237

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  600 KAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAvhlEAEKNKHNKEITVMVEKHKTElESLKHQQD 679
Cdd:PTZ00121 1238 DAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELK---KAEEKKKADEAKKAEEKKKAD-EAKKKAEE 1313

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  680 ALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLE 759
Cdd:PTZ00121 1314 AKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKA 1393

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  760 EELSVLKDQTDKMKQELEAKMDEQK--NHHQQQVDSIIKEHEVSIQRTEKALKDQInqlelllkeRDKHLKEHQAHVENL 837
Cdd:PTZ00121 1394 DEAKKKAEEDKKKADELKKAAAAKKkaDEAKKKAEEKKKADEAKKKAEEAKKADEA---------KKKAEEAKKAEEAKK 1464

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  838 EADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEV----EAQKKDVCTELDA 913
Cdd:PTZ00121 1465 KAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAkkaeEAKKADEAKKAEE 1544

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  914 HKiQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSI 993
Cdd:PTZ00121 1545 KK-KADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAE 1623

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  994 HILNEEYETKFKNQ-EKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDA 1072
Cdd:PTZ00121 1624 ELKKAEEEKKKVEQlKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKK 1703

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1073 VSRLETNQKEQIESLTEVHRRElnDVISIWEKKLNQQAEELQEIHEiQLQEKEQEVAELKQKILLFGCEKEEMNKEITWL 1152
Cdd:PTZ00121 1704 AEELKKKEAEEKKKAEELKKAE--EENKIKAEEAKKEAEEDKKKAE-EAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAV 1780

                         730       740
                  ....*....|....*....|....*..
gi 530372322 1153 KEEGVKQDTTLNELQEQLKQKSAHVNS 1179
Cdd:PTZ00121 1781 IEEELDEEDEKRRMEVDKKIKDIFDNF 1807
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 373-692 3.80e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 68.81  E-value: 3.80e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  373 ALQEQLDERLQELEKIKDLHM-AEKTKLITQLRDAKNLIEQLEqdkgmviaetkrqmhETLEMKEEEIAQLRSRIKQMTT 451
Cdd:COG1196   217 ELKEELKELEAELLLLKLRELeAELEELEAELEELEAELEELE---------------AELAELEAELEELRLELEELEL 281

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  452 QGEELREQkEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIektsEEERISLQQELSRVKQEVVDVMKK--SS 529
Cdd:COG1196   282 ELEEAQAE-EYELLAELARLEQDIARLEERRRELEERLEELEEELAEL----EEELEELEEELEELEEELEEAEEEleEA 356

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  530 EEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENK 609
Cdd:COG1196   357 EAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEE 436

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  610 LRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVL 689
Cdd:COG1196   437 EEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLL 516


                  ...
gi 530372322  690 KQQ 692
Cdd:COG1196   517 AGL 519
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1104-1899 4.25e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 68.93  E-value: 4.25e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1104 KKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQK---------- 1173
Cdd:TIGR02168  203 KSLERQAEKAERYKELKAELRELELALLVLRLEELREELEELQEELKEAEEELEELTAELQELEEKLEELrlevseleee 282

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1174 ----SAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEK 1249
Cdd:TIGR02168  283 ieelQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEE 362

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1250 SNKSLEDKSLEFKKLSEE-----------------LAIQLDICCKKTEALLEAKTNELINISSSKTNAILSRISHCQHRT 1312
Cdd:TIGR02168  363 LEAELEELESRLEELEEQletlrskvaqlelqiasLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAEL 442

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1313 TKVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEK 1392
Cdd:TIGR02168  443 EELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGIL 522

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1393 ESCITQLKKE----------LSENINAVTLmkEELKEKKVEISSLSKQL--------------TDLNVQLQNSISLSEKE 1448
Cdd:TIGR02168  523 GVLSELISVDegyeaaieaaLGGRLQAVVV--ENLNAAKKAIAFLKQNElgrvtflpldsikgTEIQGNDREILKNIEGF 600

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1449 AAISSLRKQYDEEKCELLDQVQDLSFKVDTLsKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLElKSKE 1528
Cdd:TIGR02168  601 LGVAKDLVKFDPKLRKALSYLLGGVLVVDDL-DNALELAKKLRPGYRIVTLDGDLVRPGGVITGGSAKTNSSILE-RRRE 678

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1529 AYEKDEQINLLKEELDQQNKRFDCLKGE---MEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKN 1605
Cdd:TIGR02168  679 IEELEEKIEELEEKIAELEKALAELRKEleeLEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTE 758

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1606 YNQQKDIEHKELVQKLQHFQELGEEKdnrvKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLE 1685
Cdd:TIGR02168  759 LEAEIEELEERLEEAEEELAEAEAEI----EELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLERRIA 834

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1686 S--ESAAKLAELKRKAEQKIAAIKKQlLSQMEEKEEQYKKGTESHL---SELNTKLQEREREVHILEEKLKSVES--SQS 1758
Cdd:TIGR02168  835 AteRRLEDLEEQIEELSEDIESLAAE-IEELEELIEELESELEALLnerASLEEALALLRSELEELSEELRELESkrSEL 913

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1759 ETLIVPRSAKNVAAYTEQEEAdsqgcvqktyEEKISVLQRNLTEKEKLLQRVGQEKEETVSSHFEmrcQYQERLIKLEHA 1838
Cdd:TIGR02168  914 RRELEELREKLAQLELRLEGL----------EVRIDNLQERLSEEYSLTLEEAEALENKIEDDEE---EARRRLKRLENK 980

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 530372322  1839 EAKqhedqsmIGHLQ----EELEEKNKKYSLIVAQHVEKEGGKNNIQ---------AKQNLENVFDDVQKTLQE 1899
Cdd:TIGR02168  981 IKE-------LGPVNlaaiEEYEELKERYDFLTAQKEDLTEAKETLEeaieeidreARERFKDTFDQVNENFQR 1047
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1502-2141 4.43e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 68.42  E-value: 4.43e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1502 KKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDclkgEMEDDKSKMEKKESNLETELKSQTAR 1581
Cdd:COG1196   235 RELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELE----EAQAEEYELLAELARLEQDIARLEER 310

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1582 IMELEDHITQKTIEIESLNEVLKNYNQQKD---IEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELET 1658
Cdd:COG1196   311 RRELEERLEELEEELAELEEELEELEEELEeleEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLE 390

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1659 KKKELehvnLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQykkgteSHLSELNTKLQE 1738
Cdd:COG1196   391 ALRAA----AELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAA------EEEAELEEEEEA 460

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1739 REREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQRVGQEKEETV 1818
Cdd:COG1196   461 LLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAAL 540

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1819 SSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGH---LQEELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENVFDDVQK 1895
Cdd:COG1196   541 EAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRatfLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGD 620

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1896 TLQEKELTCQILEQKIKELDSCLVRQKEVhRVEMEELtskyeklqalqqmdgrnkptelleenteekskshlvqpkllsn 1975
Cdd:COG1196   621 TLLGRTLVAARLEAALRRAVTLAGRLREV-TLEGEGG------------------------------------------- 656

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1976 meaqhNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMRE 2055
Cdd:COG1196   657 -----SAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLE 731

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 2056 FNTQLAQKEQELEMTIKETINKAQEVEAELLESHQEETNQLLKKIAEK-------DDDLKRTAKRYEEildareeeMTAK 2128
Cdd:COG1196   732 AEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALgpvnllaIEEYEELEERYDF--------LSEQ 803

                         650
                  ....*....|...
gi 530372322 2129 VRDLQTQLEELQK 2141
Cdd:COG1196   804 REDLEEARETLEE 816
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 758-1081 5.34e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 68.42  E-value: 5.34e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  758 LEEELSVLKDQTDKMK--QELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVE 835
Cdd:COG1196   198 LERQLEPLERQAEKAEryRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELE 277

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  836 NLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHK 915
Cdd:COG1196   278 ELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAE 357

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  916 IQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVekenmILQMREGQKKEIEILTQKLSAKEDSIHI 995
Cdd:COG1196   358 AELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEE-----LEEAEEALLERLERLEEELEELEEALAE 432

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  996 LNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSR 1075
Cdd:COG1196   433 LEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKA 512


                  ....*.
gi 530372322 1076 LETNQK 1081
Cdd:COG1196   513 ALLLAG 518
PTZ00121 PTZ00121
MAEBL; Provisional
 1445-1913 6.93e-11

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 68.24  E-value: 6.93e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1445 SEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQiQLEL 1524
Cdd:PTZ00121 1286 AEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAE-AAEE 1364

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1525 KSKEAYEKDEQINLLKEELD---QQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARimeledhitqktieiESLNE 1601
Cdd:PTZ00121 1365 KAEAAEKKKEEAKKKADAAKkkaEEKKKADEAKKKAEEDKKKADELKKAAAAKKKADEAK---------------KKAEE 1429

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1602 VLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQvysMKAELETKKKELEHVNLSVKSKEEELKALE 1681
Cdd:PTZ00121 1430 KKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADEAK---KKAEEAKKADEAKKKAEEAKKKADEAKKAA 1506

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1682 DRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETL 1761
Cdd:PTZ00121 1507 EAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEA 1586

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1762 --IVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQ-RNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHA 1838
Cdd:PTZ00121 1587 kkAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEElKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEE 1666

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 530372322 1839 EAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKE 1913
Cdd:PTZ00121 1667 AKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEE 1741
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1516-2141 7.05e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 68.04  E-value: 7.05e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1516 KELQIQLELKSKEAYEKdeQINLLKEELDQQNKRFDclkgEMEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIE 1595
Cdd:COG1196   216 RELKEELKELEAELLLL--KLRELEAELEELEAELE----ELEAELEELEAELAELEAELEELRLELEELELELEEAQAE 289

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1596 IESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDN---RVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKS 1672
Cdd:COG1196   290 EYELLAELARLEQDIARLEERRRELEERLEELEEELAEleeELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLE 369

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1673 KEEELKALEDRLESESAAKLAELKRKAEQkiaaikKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKS 1752
Cdd:COG1196   370 AEAELAEAEEELEELAEELLEALRAAAEL------AAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEA 443

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1753 VESSQSETLivprsaknvAAYTEQEEAdsqgcvqktyEEKISVLQRNLTEKEKLLQRVGQEKEETVSshfemrcqyqeRL 1832
Cdd:COG1196   444 LEEAAEEEA---------ELEEEEEAL----------LELLAELLEEAALLEAALAELLEELAEAAA-----------RL 493

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1833 IKLEHAEAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENvfDDVQKTLQEKELTCQILEQKIK 1912
Cdd:COG1196   494 LLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQ--NIVVEDDEVAAAAIEYLKAAKA 571

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1913 ELDSCLVRQKEVHRVEMEELTSKYEKLQA--LQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGA 1990
Cdd:COG1196   572 GRATFLPLDKIRARAALAAALARGAIGAAvdLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTL 651

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1991 EREKQKLGKEIVRLQ-KDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEM 2069
Cdd:COG1196   652 EGEGGSAGGSLTGGSrRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLE 731

                         570       580       590       600       610       620       630
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 530372322 2070 TIKETINKAQEVEAELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEI----LDAREE--EMTAKVRDLQTQLEELQK 2141
Cdd:COG1196   732 AEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALgpvnLLAIEEyeELEERYDFLSEQREDLEE 809
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1059-1944 7.42e-11

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 67.77  E-value: 7.42e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1059 LEMAQANSAGISDAVSRLETN------QKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEiQLQEKEQEVAELK 1132
Cdd:TIGR02168  181 LERTRENLDRLEDILNELERQlkslerQAEKAERYKELKAELRELELALLVLRLEELREELEELQE-ELKEAEEELEELT 259

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1133 QKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQL 1212
Cdd:TIGR02168  260 AELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEEL 339

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1213 VELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEELAIQldicckktealleakTNELIN 1292
Cdd:TIGR02168  340 AELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASL---------------NNEIER 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1293 ISSSktnaiLSRISHCQHRTTKVKEALLIKTctvseLEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLv 1372
Cdd:TIGR02168  405 LEAR-----LERLEDRRERLQQEIEELLKKL-----EEAELKELQAELEELEEELEELQEELERLEEALEELREELEEA- 473

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1373 teKEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEElkekkveisslsKQLTDLNVQLQNSISLSEK-EAAI 1451
Cdd:TIGR02168  474 --EQALDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQ------------SGLSGILGVLSELISVDEGyEAAI 539

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1452 SSLrkqydeekceLLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLELKSKEAYE 1531
Cdd:TIGR02168  540 EAA----------LGGRLQAVVVENLNAAKKAIAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVK 609

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1532 KDEQINLLKEELDQQNKRFDCLKGEMEDDKSKmekkesnletelkSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKD 1611
Cdd:TIGR02168  610 FDPKLRKALSYLLGGVLVVDDLDNALELAKKL-------------RPGYRIVTLDGDLVRPGGVITGGSAKTNSSILERR 676

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1612 IEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESaak 1691
Cdd:TIGR02168  677 REIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLS--- 753

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1692 lAELKRKAEQkiaaikKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETlivprsaknva 1771
Cdd:TIGR02168  754 -KELTELEAE------IEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLL----------- 815

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1772 ayteQEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGH 1851
Cdd:TIGR02168  816 ----NEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALAL 891

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1852 LQEELEEKNKKyslivaqhvEKEGGKNNIQAKQNLENvfddVQKTLQEKELTCQILEQKIKELdscLVRQKEVHRVEMEE 1931
Cdd:TIGR02168  892 LRSELEELSEE---------LRELESKRSELRRELEE----LREKLAQLELRLEGLEVRIDNL---QERLSEEYSLTLEE 955

                          890
                   ....*....|...
gi 530372322  1932 LTSKYEKLQALQQ 1944
Cdd:TIGR02168  956 AEALENKIEDDEE 968
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 372-988 7.74e-11

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 67.65  E-value: 7.74e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  372 EALQEQLDERLQELEKikdlhMAEKTklitqlRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTT 451
Cdd:COG1196   192 EDILGELERQLEPLER-----QAEKA------ERYRELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEA 260

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  452 QGEELREQKEKsERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTS---EEERISLQQELSRVKQEVVDVmkKS 528
Cdd:COG1196   261 ELAELEAELEE-LRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRrelEERLEELEEELAELEEELEEL--EE 337

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  529 SEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEksqseylkisQEKEQQESLALEELELQKKAILTESEN 608
Cdd:COG1196   338 ELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEE----------LEELAEELLEALRAAAELAAQLEELEE 407

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  609 KLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAvHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQV 688
Cdd:COG1196   408 AEEALLERLERLEEELEELEEALAELEEEEEEEEEALE-EAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEEL 486

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  689 LKQQYQTEMEKlrekcEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKAR-HKLEEELSVLKD 767
Cdd:COG1196   487 AEAAARLLLLL-----EAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALqNIVVEDDEVAAA 561

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  768 QTDKMKQELEAKMDEqknhhqQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGE 847
Cdd:COG1196   562 AIEYLKAAKAGRATF------LPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAA 635

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  848 LQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEK 927
Cdd:COG1196   636 LRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEE 715

                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 530372322  928 QNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQM--REGQKKEIEILTQKLSA 988
Cdd:COG1196   716 RLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPpdLEELERELERLEREIEA 778
PTZ00121 PTZ00121
MAEBL; Provisional
 311-838 1.09e-10

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 67.47  E-value: 1.09e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  311 EVFTKEENPESDGEPVVEDGTSVKTLETLQQRVKRQENLLKRCKET---IQSHKEQCTLLTSEKEALQEQLDERLQELEK 387
Cdd:PTZ00121 1282 ELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAkkkADAAKKKAEEAKKAAEAAKAEAEAAADEAEA 1361

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  388 IKDLHMAEKTKLITQLRDAKNLIEQLEQDKGmviAETKRQMHETLEMKEEEIAQLRSRIKQmttqGEELREQKEKSERAa 467
Cdd:PTZ00121 1362 AEEKAEAAEKKKEEAKKKADAAKKKAEEKKK---ADEAKKKAEEDKKKADELKKAAAAKKK----ADEAKKKAEEKKKA- 1433

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  468 fEELEKALSTAQKTEEARRKlkAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARK 547
Cdd:PTZ00121 1434 -DEAKKKAEEAKKADEAKKK--AEEAKKAEEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKK 1510

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  548 EQELTKKLQTR----------EREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEA 617
Cdd:PTZ00121 1511 KADEAKKAEEAkkadeakkaeEAKKADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAE 1590

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  618 ETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEM 697
Cdd:PTZ00121 1591 EARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKA 1670

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  698 EKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSvLKDQTDKMKQELE 777
Cdd:PTZ00121 1671 EEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAK-KEAEEDKKKAEEA 1749

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 530372322  778 AKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQL-ELLLKERDKHLKEHQAHVENLE 838
Cdd:PTZ00121 1750 KKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEEELDEEdEKRRMEVDKKIKDIFDNFANII 1811
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 423-1042 1.26e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 67.27  E-value: 1.26e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  423 ETKRQMHETlemkEEEIAQLRSRIKQMTTQGEELREQKEKSERAAfeELEKALSTAQKTEEARRKLKAEMDEQIKTIEKT 502
Cdd:COG1196   176 EAERKLEAT----EENLERLEDILGELERQLEPLERQAEKAERYR--ELKEELKELEAELLLLKLRELEAELEELEAELE 249

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  503 SEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTkklQTREREFQEQMKVALEKSQSEyLKISQ 582
Cdd:COG1196   250 ELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELAR---LEQDIARLEERRRELEERLEE-LEEEL 325

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  583 EKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEitv 662
Cdd:COG1196   326 AELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQL--- 402

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  663 mvEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEiifQAHIEEMNEKTLEKLDVKQTELE 742
Cdd:COG1196   403 --EELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAEL---EEEEEALLELLAELLEEAALLEA 477

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  743 SLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSII---KEHEVSIQ-RTEKALKDQINQLEL 818
Cdd:COG1196   478 ALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIgveAAYEAALEaALAAALQNIVVEDDE 557

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  819 LLKERDKHLKEHQAH-VENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQV 897
Cdd:COG1196   558 VAAAAIEYLKAAKAGrATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALR 637

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  898 AEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKK 977
Cdd:COG1196   638 RAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERL 717

                         570       580       590       600       610       620
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 530372322  978 EIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLldqeAKLKKELEN 1042
Cdd:COG1196   718 EEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELEREL----ERLEREIEA 778
PTZ00121 PTZ00121
MAEBL; Provisional
 1446-2183 1.46e-10

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 67.09  E-value: 1.46e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1446 EKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSK-------EKISALEQVDDWSNKFSEWKKKAQ-SRFTQHQNTVKE 1517
Cdd:PTZ00121 1209 EEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKaeeernnEEIRKFEEARMAHFARRQAAIKAEeARKADELKKAEE 1288

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1518 LQIQLELKSKEAYEKDEQINLLKEE---LDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMELEdhitqKTI 1594
Cdd:PTZ00121 1289 KKKADEAKKAEEKKKADEAKKKAEEakkADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAE-----AAE 1363

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1595 EIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEkiltlenqvysMKAELETKKKELEhvnlSVKSKE 1674
Cdd:PTZ00121 1364 EKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADE-----------LKKAAAAKKKADE----AKKKAE 1428

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1675 EELKALEDRLESESAAKLAELKRKAEQKIAAikkqllsqmeekEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVE 1754
Cdd:PTZ00121 1429 EKKKADEAKKKAEEAKKADEAKKKAEEAKKA------------EEAKKKAEEAKKADEAKKKAEEAKKADEAKKKAEEAK 1496

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1755 SSQSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQrvgQEKEETVSSHFEMRCQYQERlik 1834
Cdd:PTZ00121 1497 KKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADE---LKKAEELKKAEEKKKAEEAK--- 1570

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1835 lehaeaKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENVF--DDVQKTLQEKELTCQILEQKIK 1912
Cdd:PTZ00121 1571 ------KAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIkaEELKKAEEEKKKVEQLKKKEAE 1644

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1913 EldsclVRQKEVHRVEMEELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSHLVQpkllsnmeaqhndlEFKLAGAER 1992
Cdd:PTZ00121 1645 E-----KKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKK--------------EAEEAKKAE 1705

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1993 EKQKLGKEIVRLQKDLRMLRKEHQQELEILKKEydqEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIK 2072
Cdd:PTZ00121 1706 ELKKKEAEEKKKAEELKKAEEENKIKAEEAKKE---AEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKEKEAVIE 1782

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 2073 ETINKAQEVEAELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEEN 2152
Cdd:PTZ00121 1783 EELDEEDEKRRMEVDKKIKDIFDNFANIIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQLEEADAFEKHKFNKNNENGE 1862

                         730       740       750
                  ....*....|....*....|....*....|...
gi 530372322 2153 PGNDNTQLAQKTTLISD--SKLKEQEFREQIHN 2183
Cdd:PTZ00121 1863 DGNKEADFNKEKDLKEDdeEEIEEADEIEKIDK 1895
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 366-664 1.52e-10

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 66.88  E-value: 1.52e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  366 LLTSEKEALQEQLDERLQELEKIkDLHMAEKTKLITQLRDAKNLIEQLEQDKGmviaETKRQMHETLEMKEEEIAQLRSR 445
Cdd:COG1196   236 ELEAELEELEAELEELEAELEEL-EAELAELEAELEELRLELEELELELEEAQ----AEEYELLAELARLEQDIARLEER 310

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  446 IKQMTTQGEELREQKEKSERAAfEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVM 525
Cdd:COG1196   311 RRELEERLEELEEELAELEEEL-EELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELL 389

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  526 KKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEylKISQEKEQQESLALEELELQKKAILTE 605
Cdd:COG1196   390 EALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEE--EEALEEAAEEEAELEEEEEALLELLAE 467

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 530372322  606 SENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMV 664
Cdd:COG1196   468 LLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAGAV 526
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 343-1135 1.68e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 66.62  E-value: 1.68e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   343 VKRQENLLKRCKETIQSHKE--------QCTLLTSEKEALQEQLDERLQELEKikdlhmaektkLITQLRDAKNLIEQLE 414
Cdd:TIGR02168  198 LERQLKSLERQAEKAERYKElkaelrelELALLVLRLEELREELEELQEELKE-----------AEEELEELTAELQELE 266

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   415 QDkgmvIAETKRQMHEtlemKEEEIAQLRSRIKQMTTQGEELREQKE--KSERAAFEELEKALSTAQKTEEARRKLKAEM 492
Cdd:TIGR02168  267 EK----LEELRLEVSE----LEEEIEELQKELYALANEISRLEQQKQilRERLANLERQLEELEAQLEELESKLDELAEE 338

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   493 DEQIKTIEKTSEEERISLQQELSRVKQEVVDvmkksSEEQIAKLQKLHEKelARKEQELTKKLQTREREFQEQMKVALEK 572
Cdd:TIGR02168  339 LAELEEKLEELKEELESLEAELEELEAELEE-----LESRLEELEEQLET--LRSKVAQLELQIASLNNEIERLEARLER 411

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   573 SQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLavhleAE 652
Cdd:TIGR02168  412 LEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAEREL-----AQ 486

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   653 KNKHNKEITVMVEKHKTELESLKHQQDALWTEK--LQVLKQQYQTEmeklrEKCEQEKETLL---------KDKEIIFQA 721
Cdd:TIGR02168  487 LQARLDSLERLQENLEGFSEGVKALLKNQSGLSgiLGVLSELISVD-----EGYEAAIEAALggrlqavvvENLNAAKKA 561

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   722 hIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQ----------------ELEAKMDEQKN 785
Cdd:TIGR02168  562 -IAFLKQNELGRVTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKlrkalsyllggvlvvdDLDNALELAKK 640

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   786 HHQQ----------------------QVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHqahvENLEADIKR 843
Cdd:TIGR02168  641 LRPGyrivtldgdlvrpggvitggsaKTNSSILERRREIEELEEKIEELEEKIAELEKALAELRKEL----EELEEELEQ 716

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   844 SEGELQQASAKLdvfqsyqSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQ 923
Cdd:TIGR02168  717 LRKELEELSRQI-------SALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEA 789

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   924 QLEKQNSEMEQKVKSLtqvyeSKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETK 1003
Cdd:TIGR02168  790 QIEQLKEELKALREAL-----DELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEEL 864

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1004 FKNQEKKMEKVK--QKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSagisdAVSRLETNQK 1081
Cdd:TIGR02168  865 EELIEELESELEalLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLEL-----RLEGLEVRID 939

                          810       820       830       840       850
                   ....*....|....*....|....*....|....*....|....*....|....
gi 530372322  1082 EQIESLTEVHRRELndvisiwekklnQQAEELQEIHEIQLQEKEQEVAELKQKI 1135
Cdd:TIGR02168  940 NLQERLSEEYSLTL------------EEAEALENKIEDDEEEARRRLKRLENKI 981
PTZ00121 PTZ00121
MAEBL; Provisional
 371-1098 4.05e-10

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 65.55  E-value: 4.05e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  371 KEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNL--IEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQ 448
Cdd:PTZ00121 1173 EDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEErkAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNE 1252

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  449 MTTQGEELREQKEKSERAAF--------EELEKAlSTAQKTEEARrklKAEMDEQIKTIEKTSEEERislqqELSRVKQE 520
Cdd:PTZ00121 1253 EIRKFEEARMAHFARRQAAIkaeearkaDELKKA-EEKKKADEAK---KAEEKKKADEAKKKAEEAK-----KADEAKKK 1323

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  521 VVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKlqtrEREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKK 600
Cdd:PTZ00121 1324 AEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAAD----EAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKK 1399

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  601 AiltESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKdlavhleAEKNKHNKEITVMVEKHKTELESLKHQQDA 680
Cdd:PTZ00121 1400 A---EEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKK-------AEEAKKADEAKKKAEEAKKAEEAKKKAEEA 1469

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  681 LWTEKLQVlKQQYQTEMEKLREKCEQEKEtllKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEE 760
Cdd:PTZ00121 1470 KKADEAKK-KAEEAKKADEAKKKAEEAKK---KADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEK 1545

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  761 ELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKehQAHVENLEAD 840
Cdd:PTZ00121 1546 KKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAK--KAEEAKIKAE 1623

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  841 IKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQV--AEVEAQKKDVCTELDAHKIQV 918
Cdd:PTZ00121 1624 ELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAkkAEEDEKKAAEALKKEAEEAKK 1703

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  919 QDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEkenmiLQMREGQKKEIEILTQKLSAKEDSIHI--- 995
Cdd:PTZ00121 1704 AEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEE-----AKKDEEEKKKIAHLKKEEEKKAEEIRKeke 1778

                         650       660       670       680       690       700       710       720
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  996 ------LNEEYETKFKNQEKKMEKVKQKAKEMQE---------TLKKKLLDQEAKLKKELENTALELSQKEKQ--FNAKM 1058
Cdd:PTZ00121 1779 avieeeLDEEDEKRRMEVDKKIKDIFDNFANIIEggkegnlviNDSKEMEDSAIKEVADSKNMQLEEADAFEKhkFNKNN 1858

                         730       740       750       760
                  ....*....|....*....|....*....|....*....|
gi 530372322 1059 LEMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELNDV 1098
Cdd:PTZ00121 1859 ENGEDGNKEADFNKEKDLKEDDEEEIEEADEIEKIDKDDI 1898
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 765-1559 4.15e-10

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 65.46  E-value: 4.15e-10
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   765 LKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHE---VSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADI 841
Cdd:TIGR02168  218 LKAELRELELALLVLRLEELREELEELQEELKEAEeelEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEI 297

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   842 KRSEGELQQASAKLDvfqsyqsATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDL 921
Cdd:TIGR02168  298 SRLEQQKQILRERLA-------NLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEEL 370

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   922 MQQLEKQNSEMEQKVKSLTQVYEsKLEDGNKEQE----QTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILN 997
Cdd:TIGR02168  371 ESRLEELEEQLETLRSKVAQLEL-QIASLNNEIErleaRLERLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEEL 449

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   998 EEYETKFKNQEKKMEKVKQKAKEMQETLkKKLLDQEAKLKKELENTALELSQKEK-QFNAKMLEMAQANSAGISDAVSRL 1076
Cdd:TIGR02168  450 EELQEELERLEEALEELREELEEAEQAL-DAAERELAQLQARLDSLERLQENLEGfSEGVKALLKNQSGLSGILGVLSEL 528

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1077 ETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAE-------------ELQEIHEIQLQEKEQEVAELKQKILLFGCEKE 1143
Cdd:TIGR02168  529 ISVDEGYEAAIEAALGGRLQAVVVENLNAAKKAIAflkqnelgrvtflPLDSIKGTEIQGNDREILKNIEGFLGVAKDLV 608

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1144 EMNKEIT-----WLkeEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHleklEVDLNKSLKENTFLQEQLVELKML 1218
Cdd:TIGR02168  609 KFDPKLRkalsyLL--GGVLVVDDLDNALELAKKLRPGYRIVTLDGDLVRPG----GVITGGSAKTNSSILERRREIEEL 682

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1219 AEEDKR---KVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEELAIQLdiccKKTEALLEAKTNELINISS 1295
Cdd:TIGR02168  683 EEKIEEleeKIAELEKALAELRKELEELEEELEQLRKELEELSRQISALRKDLARLE----AEVEQLEERIAQLSKELTE 758

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1296 SktnailsrishcQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEK 1375
Cdd:TIGR02168  759 L------------EAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERL 826

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1376 EALQKEGGNQQQAASEkescITQLKKELSENINAVTLmkeelkekkvEISSLSKQLTDLNVQLQ-NSISLSEKEAAISSL 1454
Cdd:TIGR02168  827 ESLERRIAATERRLED----LEEQIEELSEDIESLAA----------EIEELEELIEELESELEaLLNERASLEEALALL 892

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1455 RKQYDeekcELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKA---QSRFTQHQNTVKELQIQLELKSKEAYE 1531
Cdd:TIGR02168  893 RSELE----ELSEELRELESKRSELRRELEELREKLAQLELRLEGLEVRIdnlQERLSEEYSLTLEEAEALENKIEDDEE 968

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|...
gi 530372322  1532 K-DEQINLLK--------------EELDQQNKRFDCLKGEMED 1559
Cdd:TIGR02168  969 EaRRRLKRLEnkikelgpvnlaaiEEYEELKERYDFLTAQKED 1011
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 795-1542 3.13e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 62.78  E-value: 3.13e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   795 IKEHEVSIQRTEK---ALKDQINQLELLLKERDKHLKEHQAHVENLEADIKR-SEGELQQASAKLDVFQSYQSATHEQTK 870
Cdd:TIGR02169  232 KEALERQKEAIERqlaSLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDlGEEEQLRVKEKIGELEAEIASLERSIA 311

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   871 AYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSL------TQVYE 944
Cdd:TIGR02169  312 EKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFaetrdeLKDYR 391

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   945 SKLEDGNKEQEQTKQILVEKENMILQMREgqkkEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQkAKEMQET 1024
Cdd:TIGR02169  392 EKLEKLKREINELKRELDRLQEELQRLSE----ELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQ-LAADLSK 466

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1025 LKKKLLDQEA---KLKKELENTALELSQKEKQ---------FNAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHR 1092
Cdd:TIGR02169  467 YEQELYDLKEeydRVEKELSKLQRELAEAEAQaraseervrGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVAAG 546

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1093 RELNDVISIWEKKLNQQAEELQE----------IHEIQLQEKEQEVAELKQKIL----LFGCEKEEMNKEITWLKEEGVK 1158
Cdd:TIGR02169  547 NRLNNVVVEDDAVAKEAIELLKRrkagratflpLNKMRDERRDLSILSEDGVIGfavdLVEFDPKYEPAFKYVFGDTLVV 626

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1159 QDTT----------LNELQEQLKQKSAHV-------NSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEE 1221
Cdd:TIGR02169  627 EDIEaarrlmgkyrMVTLEGELFEKSGAMtggsrapRGGILFSRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDE 706

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1222 DKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEELA---IQLDICCKKTEALLEAKTNELINISSSKT 1298
Cdd:TIGR02169  707 LSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIEnvkSELKELEARIEELEEDLHKLEEALNDLEA 786

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1299 NAILSRISHCQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEAL 1378
Cdd:TIGR02169  787 RLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEEL 866

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1379 QKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNsisLSEKEAAISSLRKQY 1458
Cdd:TIGR02169  867 EEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEA---LEEELSEIEDPKGED 943

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1459 DEEKCELLDqVQDLSFKVDTLsKEKISALEQVDdwsNKFSEWKKKAQSRFtqhqNTVKELQIQLELKSKEAYEKDEQINL 1538
Cdd:TIGR02169  944 EEIPEEELS-LEDVQAELQRV-EEEIRALEPVN---MLAIQEYEEVLKRL----DELKEKRAKLEEERKAILERIEEYEK 1014


                   ....
gi 530372322  1539 LKEE 1542
Cdd:TIGR02169 1015 KKRE 1018
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1499-2138 3.93e-09

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 62.00  E-value: 3.93e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1499 EWKKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKgEMEDDKSKMEKKESNLETELKSQ 1578
Cdd:PRK03918  179 ERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELE-ELKEEIEELEKELESLEGSKRKL 257

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1579 TARIMELEDHITQKTIEIESLNEVLKNYNQQKdiEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELET 1658
Cdd:PRK03918  258 EEKIRELEERIEELKKEIEELEEKVKELKELK--EKAEEYIKLSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEE 335

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1659 KKKELEHVNLSVKSKEEELKALEDRLES-ESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQ 1737
Cdd:PRK03918  336 KEERLEELKKKLKELEKRLEELEERHELyEEAKAKKEELERLKKRLTGLTPEKLEKELEELEKAKEEIEEEISKITARIG 415

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1738 EREREVHILEEKLKSVESSQSETLIVPRSaknvaaYTEQEEADsqgcVQKTYEEKISVLQRNLTEKEKLLQRVGQEKEEt 1817
Cdd:PRK03918  416 ELKKEIKELKKAIEELKKAKGKCPVCGRE------LTEEHRKE----LLEEYTAELKRIEKELKEIEEKERKLRKELRE- 484

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1818 vsshFEMRCQYQERLIKL-EHAEAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEKEGG----KNNIQAKQNLENVFDD 1892
Cdd:PRK03918  485 ----LEKVLKKESELIKLkELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEikslKKELEKLEELKKKLAE 560

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1893 VQKTLQEKELTCQILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKLqalqqmdgrnkptelleenteekskshlvqpkl 1972
Cdd:PRK03918  561 LEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLEL--------------------------------- 607

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1973 lSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEhqqeLEILKKEYDQEREEKIKQEQEDLELKHNSTLKQL 2052
Cdd:PRK03918  608 -KDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKE----LEELEKKYSEEEYEELREEYLELSRELAGLRAEL 682

                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 2053 mrefntqlaqkeqelemtiketinkaqeveaELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDARE--EEMTAKVR 2130
Cdd:PRK03918  683 -------------------------------EELEKRREEIKKTLEKLKEELEEREKAKKELEKLEKALErvEELREKVK 731


                  ....*...
gi 530372322 2131 DLQTQLEE 2138
Cdd:PRK03918  732 KYKALLKE 739
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 370-1237 4.11e-09

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 62.30  E-value: 4.11e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   370 EKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETkrqmheTLEMKEEEIAQLRSRIKQM 449
Cdd:pfam02463  171 KKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEY------LLYLDYLKLNEERIDLLQE 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   450 TTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSS 529
Cdd:pfam02463  245 LLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKK 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   530 EEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKS--QSEYLKISQEKEQQESLALEELELQKKAILTESE 607
Cdd:pfam02463  325 KAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLeqLEEELLAKKKLESERLSSAAKLKEEELELKSEEE 404

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   608 NKLRDLQQEAETYRTRILELESSLEKSLQENKnqskdLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQ 687
Cdd:pfam02463  405 KEAQLLLELARQLEDLLKEEKKEELEILEEEE-----ESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQL 479

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   688 VLKQQYQTEMEKLREkcEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKD 767
Cdd:pfam02463  480 VKLQEQLELLLSRQK--LEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATA 557

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   768 QTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGE 847
Cdd:pfam02463  558 DEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKL 637

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   848 LQQASAKLDVFQSYQSATHEQTkayEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEK 927
Cdd:pfam02463  638 KESAKAKESGLRKGVSLEEGLA---EKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKK 714

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   928 QNSEMEQKVKSLTQVYESKL-EDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKN 1006
Cdd:pfam02463  715 LKLEAEELLADRVQEAQDKInEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEE 794

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1007 QEKKMEKVKQKAKEmqetlKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIES 1086
Cdd:pfam02463  795 KLKAQEEELRALEE-----ELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELL 869

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1087 LTEVHRRELNDVISIWEKKLNQQAEELQEIHE-IQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNE 1165
Cdd:pfam02463  870 QELLLKEEELEEQKLKDELESKEEKEKEEKKElEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKE 949

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 530372322  1166 LQEQLKQKSAHVNSLAQDEtklKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTD 1237
Cdd:pfam02463  950 KEENNKEEEEERNKRLLLA---KEELGKVNLMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQR 1018
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1973-2193 7.83e-09

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 61.11  E-value: 7.83e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1973 LSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKhnsTLKQL 2052
Cdd:COG1196   269 LEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELE---ELEEE 345

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 2053 MREFNTQLAQKEQELEMTIKETINKAQEVEA--ELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAKVR 2130
Cdd:COG1196   346 LEEAEEELEEAEAELAEAEEALLEAEAELAEaeEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEE 425

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 530372322 2131 DLQTQLEELQKKYQQKLEQEENPGNDNTQLAQKTTLISDSKLKEQEFREQIHNLEDRLKKYEK 2193
Cdd:COG1196   426 LEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAE 488
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 354-673 8.63e-09

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 60.91  E-value: 8.63e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   354 KETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQ----LEQDKGMVIAETKRQMH 429
Cdd:pfam17380  281 QKAVSERQQQEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQermaMERERELERIRQEERKR 360

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   430 ETLEMKEEEIAQLRSRIKQMttqgEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEqiktIEKTSEEERIS 509
Cdd:pfam17380  361 ELERIRQEEIAMEISRMREL----ERLQMERQQKNERVRQELEAARKVKILEEERQRKIQQQKVE----MEQIRAEQEEA 432

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   510 LQQELSRVKQEVVDVMKKSSEEQIAK---LQKLHEKELARKEQELTKKLQTRER-EFQEQMKVALEKSQSEYLKISQEKE 585
Cdd:pfam17380  433 RQREVRRLEEERAREMERVRLEEQERqqqVERLRQQEEERKRKKLELEKEKRDRkRAEEQRRKILEKELEERKQAMIEEE 512

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   586 QQESLALEELELQKKAILTESEnklrdlQQEAETYRTRILELESslEKSLQENKNQSKDLAVHLEA-EKNKHNKEITVMV 664
Cdd:pfam17380  513 RKRKLLEKEMEERQKAIYEEER------RREAEEERRKQQEMEE--RRRIQEQMRKATEERSRLEAmEREREMMRQIVES 584


                   ....*....
gi 530372322   665 EKHKTELES 673
Cdd:pfam17380  585 EKARAEYEA 593
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 910-1738 9.79e-09

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 60.85  E-value: 9.79e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   910 ELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYEsKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAK 989
Cdd:TIGR02169  167 EFDRKKEKALEELEEVEENIERLDLIIDEKRQQLE-RLRREREKAERYQALLKEKREYEGYELLKEKEALERQKEAIERQ 245

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   990 EDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQAnSAGI 1069
Cdd:TIGR02169  246 LASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASLERSIAEKERELEDA-EERL 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1070 SDAVSRLEtNQKEQIESLTE------VHRRELNDVISIWEKKLNQQAEELQEIhEIQLQEKEQEVAELKQKILLFGCEKE 1143
Cdd:TIGR02169  325 AKLEAEID-KLLAEIEELEReieeerKRRDKLTEEYAELKEELEDLRAELEEV-DKEFAETRDELKDYREKLEKLKREIN 402

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1144 EMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLnkslkentflqEQLVELKMLAEEDK 1223
Cdd:TIGR02169  403 ELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKL-----------EQLAADLSKYEQEL 471

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1224 RKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEELAIQLDICCKKTEALLEAKTNELINISSSKTNAI-- 1301
Cdd:TIGR02169  472 YDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASIQGVHGTVAQLGSVGERYATAIEVAAGNRLnn 551

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1302 ----------------------------LSRISHCQHRTTKVKEALLI----------------------KTCTVSELEA 1331
Cdd:TIGR02169  552 vvveddavakeaiellkrrkagratflpLNKMRDERRDLSILSEDGVIgfavdlvefdpkyepafkyvfgDTLVVEDIEA 631

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1332 ------QLRQLTEEQNTL----------NISFQQATHQLEEKEnQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESC 1395
Cdd:TIGR02169  632 arrlmgKYRMVTLEGELFeksgamtggsRAPRGGILFSRSEPA-ELQRLRERLEGLKRELSSLQSELRRIENRLDELSQE 710

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1396 ITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSIS--------LSEKEAAISSLRKQ----YDEEKC 1463
Cdd:TIGR02169  711 LSDASRKIGEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQEIENVKSelkelearIEELEEDLHKLEEAlndlEARLSH 790

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1464 ELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRftqhQNTVKELQIQLELKSKEAYEKDEQINLLKEEL 1543
Cdd:TIGR02169  791 SRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKE----IQELQEQRIDLKEQIKSIEKEIENLNGKKEEL 866

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1544 DQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDiehkelvqklqh 1623
Cdd:TIGR02169  867 EEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSELKAKLEALEEELS------------ 934

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1624 fqELGEEKDNRVKEAEEkILTLEnQVYSMKAELETKKKELEHVNlsvkskeeeLKALEDRleSESAAKLAELKRKaEQKI 1703
Cdd:TIGR02169  935 --EIEDPKGEDEEIPEE-ELSLE-DVQAELQRVEEEIRALEPVN---------MLAIQEY--EEVLKRLDELKEK-RAKL 998

                          890       900       910
                   ....*....|....*....|....*....|....*
gi 530372322  1704 AAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQE 1738
Cdd:TIGR02169  999 EEERKAILERIEEYEKKKREVFMEAFEAINENFNE 1033
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 732-1405 1.82e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 60.07  E-value: 1.82e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   732 EKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQQvdSIIKEHEVSIQRTEKALKD 811
Cdd:TIGR02168  239 EELEELQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEI--SRLEQQKQILRERLANLER 316

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   812 QINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERI 891
Cdd:TIGR02168  317 QLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIA 396

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   892 LLTKQVAEVEAQKKD-------------------VCTELDAHKIQVQDLMQQLEK---QNSEMEQKVKSLTQVYESKLE- 948
Cdd:TIGR02168  397 SLNNEIERLEARLERledrrerlqqeieellkklEEAELKELQAELEELEEELEElqeELERLEEALEELREELEEAEQa 476

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   949 -DGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKfKNQEKKMEKV------------K 1015
Cdd:TIGR02168  477 lDAAERELAQLQARLDSLERLQENLEGFSEGVKALLKNQSGLSGILGVLSELISVD-EGYEAAIEAAlggrlqavvvenL 555

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1016 QKAKEMQETLKKKLLDQEAKL------KKELENTALELSQKEKQFNAKMLEMAQANSAgISDAVS------RLETNQKEQ 1083
Cdd:TIGR02168  556 NAAKKAIAFLKQNELGRVTFLpldsikGTEIQGNDREILKNIEGFLGVAKDLVKFDPK-LRKALSyllggvLVVDDLDNA 634

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1084 IESLTEVHRRE----LNDVISIWEKKLNQQAEElqeiHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEgvkq 1159
Cdd:TIGR02168  635 LELAKKLRPGYrivtLDGDLVRPGGVITGGSAK----TNSSILERRREIEELEEKIEELEEKIAELEKALAELRKE---- 706

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1160 dttLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEE 1239
Cdd:TIGR02168  707 ---LEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAE 783

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1240 FQSLKSSHEKSNKSLEDKSLEFKKLSEELaiqldicckktealleAKTNELINISSSKTNAILSRISHCQHRTTKVKEAL 1319
Cdd:TIGR02168  784 IEELEAQIEQLKEELKALREALDELRAEL----------------TLLNEEAANLRERLESLERRIAATERRLEDLEEQI 847

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1320 LIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQL 1399
Cdd:TIGR02168  848 EELSEDIESLAAEIEELEELIEELESELEALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQL 927


                   ....*.
gi 530372322  1400 KKELSE 1405
Cdd:TIGR02168  928 ELRLEG 933
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 706-1243 2.69e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 59.57  E-value: 2.69e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  706 QEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQtelESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKmDEQKN 785
Cdd:COG1196   216 RELKEELKELEAELLLLKLRELEAELEELEAEL---EELEAELEELEAELAELEAELEELRLELEELELELEEA-QAEEY 291

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  786 HHQQQVDSIIKEHEVSIQRtEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSAT 865
Cdd:COG1196   292 ELLAELARLEQDIARLEER-RRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEA 370

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  866 HEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYES 945
Cdd:COG1196   371 EAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEE 450

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  946 KLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEIltQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKE----- 1020
Cdd:COG1196   451 EAELEEEEEALLELLAELLEEAALLEAALAELLEEL--AEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRGLAgavav 528

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1021 ------------------------MQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGI----SDA 1072
Cdd:COG1196   529 ligveaayeaaleaalaaalqnivVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVdlvaSDL 608

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1073 VSRLETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWL 1152
Cdd:COG1196   609 READARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERL 688

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1153 KEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSK 1232
Cdd:COG1196   689 AEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERE 768

                         570
                  ....*....|.
gi 530372322 1233 LKTTDEEFQSL 1243
Cdd:COG1196   769 LERLEREIEAL 779
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 342-735 4.56e-08

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 58.91  E-value: 4.56e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   342 RVKRQENLLKRCKEtIQSHKEQCTLLTSEKEALQEQLDE---RLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKG 418
Cdd:TIGR02168  665 SAKTNSSILERRRE-IEELEEKIEELEEKIAELEKALAElrkELEELEEELEQLRKELEELSRQISALRKDLARLEAEVE 743

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   419 MViAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSEraafEELEKALSTAQKTEEARRKLKAEM-DEQIK 497
Cdd:TIGR02168  744 QL-EERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELE----AQIEQLKEELKALREALDELRAELtLLNEE 818

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   498 TIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEkelarkeqeltkKLQTREREFQEQMKVALEKSQSEY 577
Cdd:TIGR02168  819 AANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIE------------ELEELIEELESELEALLNERASLE 886

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   578 LKISQEKEQQESLALEELELQKKAilTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHN 657
Cdd:TIGR02168  887 EALALLRSELEELSEELRELESKR--SELRRELEELREKLAQLELRLEGLEVRIDNLQERLSEEYSLTLEEAEALENKIE 964

                          330       340       350       360       370       380       390
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 530372322   658 KEItvmvEKHKTELESLKHQQDALWTEKLQVLkQQYQTEMEKLREKcEQEKETLLKDKEIIFQAhIEEMNEKTLEKLD 735
Cdd:TIGR02168  965 DDE----EEARRRLKRLENKIKELGPVNLAAI-EEYEELKERYDFL-TAQKEDLTEAKETLEEA-IEEIDREARERFK 1035
Grip smart00755
golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;
2220-2263 5.55e-08

golgin-97, RanBP2alpha,Imh1p and p230/golgin-245;


Pssm-ID: 197860  Cd Length: 46  Bit Score: 50.68  E-value: 5.55e-08
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|....*.
gi 530372322   2220 PTEFEYLRKVLFEYMMGRET--KTMAKVITTVLKFPDDQTQKILER 2263
Cdd:smart00755    1 EANFEYLKNVLLQFLTLRESerETLLPVISTVLQLSPEEMQKLLEV 46
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1608-2190 9.40e-08

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 57.64  E-value: 9.40e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1608 QQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESE 1687
Cdd:COG1196   221 ELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARL 300

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1688 SAAK--LAELKRKAEQKIAAIKKQLLSQMEEKEEQykkgtESHLSELNTKLQEREREVHILEEKLKSVESSQSETL--IV 1763
Cdd:COG1196   301 EQDIarLEERRRELEERLEELEEELAELEEELEEL-----EEELEELEEELEEAEEELEEAEAELAEAEEALLEAEaeLA 375

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1764 PRSAKNVAAYTEQEEADSQgcvQKTYEEKISVLQRNLTEKEKLLQRVGQEKEEtvsshfemrcQYQERLIKLEHAEAKQH 1843
Cdd:COG1196   376 EAEEELEELAEELLEALRA---AAELAAQLEELEEAEEALLERLERLEEELEE----------LEEALAELEEEEEEEEE 442

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1844 EDQSMIGHLQEELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKELDScLVRQKE 1923
Cdd:COG1196   443 ALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALL-LAGLRG 521

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1924 VHRVEMEELTSKYEKLQALQQMDGRnkptelleenteekskshLVQPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVR 2003
Cdd:COG1196   522 LAGAVAVLIGVEAAYEAALEAALAA------------------ALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIR 583

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 2004 LQKDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEA 2083
Cdd:COG1196   584 ARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLT 663

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 2084 ELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEENPGNDNTQLAQK 2163
Cdd:COG1196   664 GGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLE 743

                         570       580       590
                  ....*....|....*....|....*....|....*
gi 530372322 2164 TTLIS--------DSKLKEQEFREQIHNLEDRLKK 2190
Cdd:COG1196   744 EEELLeeealeelPEPPDLEELERELERLEREIEA 778
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 423-1181 9.47e-08

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 57.77  E-value: 9.47e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   423 ETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERaaFEELEKALSTAQKTEEARRKLKAEmdEQIKTIEKt 502
Cdd:TIGR02169  170 RKKEKALEELEEVEENIERLDLIIDEKRQQLERLRREREKAER--YQALLKEKREYEGYELLKEKEALE--RQKEAIER- 244

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   503 seeERISLQQELSRVKQEVVDVMKKSseEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQmkVALEKSQSEYLKISQ 582
Cdd:TIGR02169  245 ---QLASLEEELEKLTEEISELEKRL--EEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAE--IASLERSIAEKEREL 317

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   583 EKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKeitv 662
Cdd:TIGR02169  318 EDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREK---- 393

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   663 mVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEME---KLREKCEQEKETLLKDKEIifqAHIEEMNEKTLEKLDVKQT 739
Cdd:TIGR02169  394 -LEKLKREINELKRELDRLQEELQRLSEELADLNAAiagIEAKINELEEEKEDKALEI---KKQEWKLEQLAADLSKYEQ 469

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   740 ELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQ------QVDSIIKEHEVSIQRTEKALKDQI 813
Cdd:TIGR02169  470 ELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVEEVLKASiqgvhgTVAQLGSVGERYATAIEVAAGNRL 549

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   814 NQL----ELLLKERDKHLKEHQA-----------HVENLEADIKRSEGELQQASAKLDVFQSYQSATH------------ 866
Cdd:TIGR02169  550 NNVvvedDAVAKEAIELLKRRKAgratflplnkmRDERRDLSILSEDGVIGFAVDLVEFDPKYEPAFKyvfgdtlvvedi 629

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   867 EQTKAYEEQLAQLQQKLLDLE----------TERILLTKQVAEvEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKv 936
Cdd:TIGR02169  630 EAARRLMGKYRMVTLEGELFEksgamtggsrAPRGGILFSRSE-PAELQRLRERLEGLKRELSSLQSELRRIENRLDEL- 707

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   937 KSLTQVYESKLEDGNKEQEQtkqilvekenmILQMREGQKKEIEILTQKLSAKEDSIhilneeyetkfKNQEKKMEKVKQ 1016
Cdd:TIGR02169  708 SQELSDASRKIGEIEKEIEQ-----------LEQEEEKLKERLEELEEDLSSLEQEI-----------ENVKSELKELEA 765

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1017 KAKEMQETLKKkLLDQEAKLKKELENTALELSQKEKQfnaKMLEMAQANSAGISDAVSRLetNQKEQIESLTEVHRRELN 1096
Cdd:TIGR02169  766 RIEELEEDLHK-LEEALNDLEARLSHSRIPEIQAELS---KLEEEVSRIEARLREIEQKL--NRLTLEKEYLEKEIQELQ 839

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1097 DVISIWEKKLNQQAEELQEIhEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAH 1176
Cdd:TIGR02169  840 EQRIDLKEQIKSIEKEIENL-NGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKR 918


                   ....*
gi 530372322  1177 VNSLA 1181
Cdd:TIGR02169  919 LSELK 923
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1315-2166 1.53e-07

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 57.00  E-value: 1.53e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1315 VKEALLIKTCTVSELEAQLRQLTEEQNTLnISFQQATHQLEEKENQIKSmkADIESLVTEKEALQKEggnqqqaASEKES 1394
Cdd:TIGR02169  182 VEENIERLDLIIDEKRQQLERLRREREKA-ERYQALLKEKREYEGYELL--KEKEALERQKEAIERQ-------LASLEE 251

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1395 CITQLKKELSENinavtlmKEELKEKKVEISSLSKQLTDLNVQLQNSIS--LSEKEAAISSLRKQYDEEKcellDQVQDL 1472
Cdd:TIGR02169  252 ELEKLTEEISEL-------EKRLEEIEQLLEELNKKIKDLGEEEQLRVKekIGELEAEIASLERSIAEKE----RELEDA 320

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1473 SFKVDTLSKEKISALEQVDDWSNKFSEWKKkaqsRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDC 1552
Cdd:TIGR02169  321 EERLAKLEAEIDKLLAEIEELEREIEEERK----RRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEK 396

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1553 LKGEMEDdkskMEKKESNLETELKSQTARIMELEdhitqktieieslnevlknyNQQKDIEhkelvQKLQHFQELGEEKD 1632
Cdd:TIGR02169  397 LKREINE----LKRELDRLQEELQRLSEELADLN--------------------AAIAGIE-----AKINELEEEKEDKA 447

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1633 NRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLeseSAAKLAELKRKAEQKIAAIKKQ--- 1709
Cdd:TIGR02169  448 LEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQA---RASEERVRGGRAVEEVLKASIQgvh 524

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1710 -LLSQMEEKEEQYKKGTESHLS-ELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSaknvaayteqeeADSQGCVQK 1787
Cdd:TIGR02169  525 gTVAQLGSVGERYATAIEVAAGnRLNNVVVEDDAVAKEAIELLKRRKAGRATFLPLNKM------------RDERRDLSI 592

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1788 TYEEKISVLQRNLTEKEKLLQRVgqekeetvsshfeMRCQYQERLIKLEHAEAKQHEDQSMIGHLQEELEEKNkkySLIV 1867
Cdd:TIGR02169  593 LSEDGVIGFAVDLVEFDPKYEPA-------------FKYVFGDTLVVEDIEAARRLMGKYRMVTLEGELFEKS---GAMT 656

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1868 AQHVEKEGGKNNiqakqnlenvfddvQKTLQEKELTCQILEQKIKELDSCLVRQKEVHRVEMEELTSkyeKLQALQQMDG 1947
Cdd:TIGR02169  657 GGSRAPRGGILF--------------SRSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQ---ELSDASRKIG 719

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1948 RNKPTELLEENTEEKSKshlvqpKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKehqqELEILKKEYD 2027
Cdd:TIGR02169  720 EIEKEIEQLEQEEEKLK------ERLEELEEDLSSLEQEIENVKSELKELEARIEELEEDLHKLEE----ALNDLEARLS 789

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  2028 QEREEKIKQEQEDLELKHNSTLKQLmREFNTQLAQKEQELEMTIKETINKAQEVEA--ELLESHQEETNQLLKKIAEKDD 2105
Cdd:TIGR02169  790 HSRIPEIQAELSKLEEEVSRIEARL-REIEQKLNRLTLEKEYLEKEIQELQEQRIDlkEQIKSIEKEIENLNGKKEELEE 868

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 530372322  2106 DLKRTAKRYEEiLDAREEEMTAKVRDLQTQLEELQKKYQQ-KLEQEENPGNDNTQLAQKTTL 2166
Cdd:TIGR02169  869 ELEELEAALRD-LESRLGDLKKERDELEAQLRELERKIEElEAQIEKKRKRLSELKAKLEAL 929
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
336-573 2.14e-07

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 56.46  E-value: 2.14e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  336 LETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQ------------EQLDERLQELEKikDLHMAEKT-----K 398
Cdd:COG4913   612 LAALEAELAELEEELAEAEERLEALEAELDALQERREALQrlaeyswdeidvASAEREIAELEA--ELERLDASsddlaA 689

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  399 LITQLRDAKNLIEQLEQDKGMVIAETKRqmhetlemKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTA 478
Cdd:COG4913   690 LEEQLEELEAELEELEEELDELKGEIGR--------LEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALGD 761

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  479 QKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVM--KKSSEEQIAKLQKLHEKELARKEQELTKKLQ 556
Cdd:COG4913   762 AVERELRENLEERIDALRARLNRAEEELERAMRAFNREWPAETADLDadLESLPEYLALLDRLEEDGLPEYEERFKELLN 841

                         250
                  ....*....|....*..
gi 530372322  557 TREREFQEQMKVALEKS 573
Cdd:COG4913   842 ENSIEFVADLLSKLRRA 858
PTZ00121 PTZ00121
MAEBL; Provisional
 1601-2194 2.71e-07

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 56.30  E-value: 2.71e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1601 EVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKAL 1680
Cdd:PTZ00121 1167 EEARKAEDAKKAEAARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAE 1246

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1681 EDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEE--KEEQYKKGTESHLSELNTKLQEREREVhilEEKLKSVESSQS 1758
Cdd:PTZ00121 1247 EERNNEEIRKFEEARMAHFARRQAAIKAEEARKADElkKAEEKKKADEAKKAEEKKKADEAKKKA---EEAKKADEAKKK 1323

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1759 ETlivPRSAKNVAAYTEQEEADSQGCVQKTYEEKisvlQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHA 1838
Cdd:PTZ00121 1324 AE---EAKKKADAAKKKAEEAKKAAEAAKAEAEA----AADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEA 1396

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1839 EAKQHEDQSMIGHLQEELEEKNKKYSLivAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKELDSCL 1918
Cdd:PTZ00121 1397 KKKAEEDKKKADELKKAAAAKKKADEA--KKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAKKADE 1474

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1919 VRQKEVHRVEMEELTSKYEklQALQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQKLG 1998
Cdd:PTZ00121 1475 AKKKAEEAKKADEAKKKAE--EAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADELK 1552

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1999 K-EIVRLQKDLRMLRKEHQQE---------LEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELE 2068
Cdd:PTZ00121 1553 KaEELKKAEEKKKAEEAKKAEedknmalrkAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAKIKAEELKKAEEEK 1632

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 2069 MTIKETINKAQE--VEAELLESHQEETNQLLKKIAEKDDDLKRTAkryEEILDAREEEMTAKVRDLQTQLEELQKKYQQK 2146
Cdd:PTZ00121 1633 KKVEQLKKKEAEekKKAEELKKAEEENKIKAAEEAKKAEEDKKKA---EEAKKAEEDEKKAAEALKKEAEEAKKAEELKK 1709

                         570       580       590       600
                  ....*....|....*....|....*....|....*....|....*...
gi 530372322 2147 LEQEENPGNDNTQLAQKTTLISDSKLKEQEFREQIHNLEDRLKKYEKN 2194
Cdd:PTZ00121 1710 KEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKK 1757
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 468-1272 4.96e-07

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 55.36  E-value: 4.96e-07
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   468 FEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARK 547
Cdd:pfam02463  159 EEEAAGSRLKRKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEER 238

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   548 EQELTKKLQTREREF----------QEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEA 617
Cdd:pfam02463  239 IDLLQELLRDEQEEIesskqeiekeEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKE 318

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   618 ETYRTRILELESSLEKSLQENKNQSKDLavhLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEM 697
Cdd:pfam02463  319 SEKEKKKAEKELKKEKEEIEELEKELKE---LEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEE 395

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   698 EKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELE 777
Cdd:pfam02463  396 ELELKSEEEKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLK 475

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   778 AKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKrsegelqQASAKLDV 857
Cdd:pfam02463  476 ETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVEN-------YKVAISTA 548

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   858 FQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTK-QVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKV 936
Cdd:pfam02463  549 VIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKlKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGI 628

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   937 KSLTqvYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQ 1016
Cdd:pfam02463  629 LKDT--ELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQ 706

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1017 KAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQ-FNAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHRREL 1095
Cdd:pfam02463  707 REKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQkIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKL 786

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1096 NDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCE---KEEMNKEITWLKEEGVKQDTTLNELQEQLKQ 1172
Cdd:pfam02463  787 KVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEeelEELALELKEEQKLEKLAEEELERLEEEITKE 866

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1173 KSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTfLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNK 1252
Cdd:pfam02463  867 ELLQELLLKEEELEEQKLKDELESKEEKEKEEKK-ELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEA 945

                          810       820
                   ....*....|....*....|
gi 530372322  1253 SLEDKSLEFKKLSEELAIQL 1272
Cdd:pfam02463  946 DEKEKEENNKEEEEERNKRL 965
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1543-2068 5.70e-07

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 55.05  E-value: 5.70e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1543 LDQQNKRFDCLKGEMEDDKSK-MEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDiEHKELVQKL 1621
Cdd:PRK02224  182 LSDQRGSLDQLKAQIEEKEEKdLHERLNGLESELAELDEEIERYEEQREQARETRDEADEVLEEHEERRE-ELETLEAEI 260

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1622 QHFQEL-------GEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLEsESAAKLAE 1694
Cdd:PRK02224  261 EDLRETiaetereREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLE-ECRVAAQA 339

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1695 LKRKAEQKIAAIKkQLLSQMEEKEEQYKKgTESHLSELNTKLQEREREVHILEEKLKSVESSQSETlivPRSAKNVAAYT 1774
Cdd:PRK02224  340 HNEEAESLREDAD-DLEERAEELREEAAE-LESELEEAREAVEDRREEIEELEEEIEELRERFGDA---PVDLGNAEDFL 414

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1775 E--QEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQ-----RVGQEKEEtvSSHFEMRCQYQERLIKLEhAEAKQHEDQs 1847
Cdd:PRK02224  415 EelREERDELREREAELEATLRTARERVEEAEALLEagkcpECGQPVEG--SPHVETIEEDRERVEELE-AELEDLEEE- 490

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1848 mighlQEELEEKNKKYSLIVAQHVEKEGGKNNiqaKQNLENVFDDVQKTLQEKELTCQILEQKIKELDSCLVRQKEVHRV 1927
Cdd:PRK02224  491 -----VEEVEERLERAEDLVEAEDRIERLEER---REDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAE 562

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1928 EMEELTSKYEKLQALQQMDGRNKPTELleenteekskshlvqpkllsnmeaQHNDLEFKLAGAErekqKLGKEIVRLQKd 2007
Cdd:PRK02224  563 AEEEAEEAREEVAELNSKLAELKERIE------------------------SLERIRTLLAAIA----DAEDEIERLRE- 613

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 530372322 2008 lrmlRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELE 2068
Cdd:PRK02224  614 ----KREALAELNDERRERLAEKRERKRELEAEFDEARIEEAREDKERAEEYLEQVEEKLD 670
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 895-1751 1.19e-06

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 54.21  E-value: 1.19e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   895 KQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMilqmreg 974
Cdd:pfam02463  176 KKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRD------- 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   975 QKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQF 1054
Cdd:pfam02463  249 EQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEK 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1055 NAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELN--DVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELK 1132
Cdd:pfam02463  329 ELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQleEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQ 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1133 QKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQL 1212
Cdd:pfam02463  409 LLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLEL 488

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1213 VELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSnksledKSLEFKKLSEELAIQLDICCKKTEALLEAKTNELIN 1292
Cdd:pfam02463  489 LLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIIS------AHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEE 562

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1293 ISSSKTNAILSRISHCQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLV 1372
Cdd:pfam02463  563 RQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAK 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1373 TEKEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEAAIS 1452
Cdd:pfam02463  643 AKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEEL 722

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1453 SLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLELKSKEAYEK 1532
Cdd:pfam02463  723 LADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEE 802

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1533 DEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELksqtariMELEDHITQKTIEIESLNEVLKNYNQQKDI 1612
Cdd:pfam02463  803 LRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEE-------QKLEKLAEEELERLEEEITKEELLQELLLK 875

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1613 EHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKL 1692
Cdd:pfam02463  876 EEELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKEENNK 955

                          810       820       830       840       850       860
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 530372322  1693 AELKRKAEQKIAAIKK------QLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLK 1751
Cdd:pfam02463  956 EEEEERNKRLLLAKEElgkvnlMAIEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQRLK 1020
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 191-507 1.32e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 53.92  E-value: 1.32e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   191 KEQLIQRLRRMERSLSSYRGKYSElvtAYQMLqREKKKLQGILSQSQDKSLRRIAELREELQMDQQ---AKKHLQEEFDA 267
Cdd:TIGR02169  690 LSSLQSELRRIENRLDELSQELSD---ASRKI-GEIEKEIEQLEQEEEKLKERLEELEEDLSSLEQeieNVKSELKELEA 765

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   268 SLEEKDQYISVLQTQVSLLKQRLRNGPMNV------DVLKPLPQLEPQAEVFTKEENPESDGEPVVEDgtSVKTLETLQQ 341
Cdd:TIGR02169  766 RIEELEEDLHKLEEALNDLEARLSHSRIPEiqaelsKLEEEVSRIEARLREIEQKLNRLTLEKEYLEK--EIQELQEQRI 843

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   342 RVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGmvi 421
Cdd:TIGR02169  844 DLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLS--- 920

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   422 aetkrQMHETLEMKEEEIAQLRSRIKQMTTQGEE------LREQKEKSERA----------AFEELEKALSTAQKTEEAR 485
Cdd:TIGR02169  921 -----ELKAKLEALEEELSEIEDPKGEDEEIPEEelsledVQAELQRVEEEiralepvnmlAIQEYEEVLKRLDELKEKR 995

                          330       340
                   ....*....|....*....|..
gi 530372322   486 RKLKAEMDEQIKTIEKTSEEER 507
Cdd:TIGR02169  996 AKLEEERKAILERIEEYEKKKR 1017
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1565-1909 1.43e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 53.92  E-value: 1.43e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1565 EKKESNLEtELKSQTARIMELEDHITQKTIEIESLNEvlknyNQQKDIEHKELVQKLQHFQelGEEKDNRVKEAEEKILT 1644
Cdd:TIGR02169  170 RKKEKALE-ELEEVEENIERLDLIIDEKRQQLERLRR-----EREKAERYQALLKEKREYE--GYELLKEKEALERQKEA 241

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1645 LENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAE---------QKIAAIKKQLLSQME 1715
Cdd:TIGR02169  242 IERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGeleaeiaslERSIAEKERELEDAE 321

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1716 EKEEQYKKGTESHLSELnTKLQEREREVHILEEKLKSVESSQSETLIVPRSAknvaayTEQEEADSQGCVQKT--YEEKI 1793
Cdd:TIGR02169  322 ERLAKLEAEIDKLLAEI-EELEREIEEERKRRDKLTEEYAELKEELEDLRAE------LEEVDKEFAETRDELkdYREKL 394

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1794 SVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRcqyqerlIKLEHAEAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEK 1873
Cdd:TIGR02169  395 EKLKREINELKRELDRLQEELQRLSEELADLN-------AAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKY 467

                          330       340       350
                   ....*....|....*....|....*....|....*..
gi 530372322  1874 EGGKNNIQAKQN-LENVFDDVQKTLQEKELTCQILEQ 1909
Cdd:TIGR02169  468 EQELYDLKEEYDrVEKELSKLQRELAEAEAQARASEE 504
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 1186-1755 1.75e-06

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 53.40  E-value: 1.75e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1186 KLKAHLEKLEVDLnkSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLS 1265
Cdd:COG1196   217 ELKEELKELEAEL--LLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELL 294

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1266 EELAiqldicckKTEALLEAKTNELINISSSKTNAILSRISHCQHRttkvkealliktctvSELEAQLRQLTEEQNTLNI 1345
Cdd:COG1196   295 AELA--------RLEQDIARLEERRRELEERLEELEEELAELEEEL---------------EELEEELEELEEELEEAEE 351

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1346 SFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEIS 1425
Cdd:COG1196   352 ELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALA 431

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1426 SLSKQLTDLNVQLQNSIS----LSEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWK 1501
Cdd:COG1196   432 ELEEEEEEEEEALEEAAEeeaeLEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVK 511

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1502 KKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTAR 1581
Cdd:COG1196   512 AALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAA 591

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1582 IMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKlqhfQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKK 1661
Cdd:COG1196   592 LARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAA----RLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSR 667

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1662 ELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQERER 1741
Cdd:COG1196   668 RELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEEL 747

                         570
                  ....*....|....
gi 530372322 1742 EVHILEEKLKSVES 1755
Cdd:COG1196   748 LEEEALEELPEPPD 761
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 225-1064 2.13e-06

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 53.44  E-value: 2.13e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   225 EKKKLQGILSQSQDKSLRRIAELREELQMDQQAKKHLQEEFDASLEEKDQYISVLQTQVSLLKQRLRNgpmnvdvlkplp 304
Cdd:pfam02463  174 ALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDL------------ 241

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   305 qlEPQAEVFTKEENPESDGEPVVEdgtsvktlETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQE 384
Cdd:pfam02463  242 --LQELLRDEQEEIESSKQEIEKE--------EEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVD 311

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   385 LEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSE 464
Cdd:pfam02463  312 DEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAK 391

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   465 RAAFEELEKALSTAQKTEEARRKLKAEMD-----EQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKL 539
Cdd:pfam02463  392 LKEEELELKSEEEKEAQLLLELARQLEDLlkeekKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSE 471

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   540 HEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRD---LQQE 616
Cdd:pfam02463  472 DLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAistAVIV 551

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   617 AETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTE 696
Cdd:pfam02463  552 EVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKD 631

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   697 MEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQEL 776
Cdd:pfam02463  632 TELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEE 711

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   777 EAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLD 856
Cdd:pfam02463  712 LKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEE 791

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   857 VFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKV 936
Cdd:pfam02463  792 KEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQE 871

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   937 KSLTQVYESKLED-GNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVK 1015
Cdd:pfam02463  872 LLLKEEELEEQKLkDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEPEELLLEEADEKEKE 951

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....*....
gi 530372322  1016 QKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQA 1064
Cdd:pfam02463  952 ENNKEEEEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDELEKERL 1000
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 244-1024 2.22e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 53.15  E-value: 2.22e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   244 IAELREELQMDQQAKKHLqEEFDASLEEKDQYisvlqTQVSLLKQRLRNGPMNVDVLKPLPQLEPQAEVFTKEENpesdg 323
Cdd:TIGR02169  193 IDEKRQQLERLRREREKA-ERYQALLKEKREY-----EGYELLKEKEALERQKEAIERQLASLEEELEKLTEEIS----- 261

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   324 EPVVEDGTSVKTLETLQQRVKR----QENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKL 399
Cdd:TIGR02169  262 ELEKRLEEIEQLLEELNKKIKDlgeeEQLRVKEKIGELEAEIASLERSIAEKERELEDAEERLAKLEAEIDKLLAEIEEL 341

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   400 ITQLRDAKNLIEQLeQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQ 479
Cdd:TIGR02169  342 EREIEEERKRRDKL-TEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRLSE 420

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   480 KTEEARRKLK----------AEMDEQIKTIEKtSEEERISLQQELSRVKQEVVDvmKKSSEEQIAKLQKLHEKELARKEQ 549
Cdd:TIGR02169  421 ELADLNAAIAgieakineleEEKEDKALEIKK-QEWKLEQLAADLSKYEQELYD--LKEEYDRVEKELSKLQRELAEAEA 497

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   550 ELtKKLQTREREFQEQMKVALEKSQSEYLKISQ---EKEQQESLALEELELQKKAILTESE-------NKLRDLQQEAET 619
Cdd:TIGR02169  498 QA-RASEERVRGGRAVEEVLKASIQGVHGTVAQlgsVGERYATAIEVAAGNRLNNVVVEDDavakeaiELLKRRKAGRAT 576

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   620 Y--RTRILELESSLEKSLqenKNQSKDLAVHLEAEKNKHNKEI------TVMVEkhktELESLKHQQD------------ 679
Cdd:TIGR02169  577 FlpLNKMRDERRDLSILS---EDGVIGFAVDLVEFDPKYEPAFkyvfgdTLVVE----DIEAARRLMGkyrmvtlegelf 649

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   680 ---------ALWTEKLQVLKQQYQTEMEKLREkceqEKETLLKDKEIIFQ--AHIEEMNEKTLEKLDVKQTELESLSSEL 748
Cdd:TIGR02169  650 eksgamtggSRAPRGGILFSRSEPAELQRLRE----RLEGLKRELSSLQSelRRIENRLDELSQELSDASRKIGEIEKEI 725

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   749 SEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKnhhqqQVDSIIKEHEVSIQRTEKALKD--------QINQLELLL 820
Cdd:TIGR02169  726 EQLEQEEEKLKERLEELEEDLSSLEQEIENVKSELK-----ELEARIEELEEDLHKLEEALNDlearlshsRIPEIQAEL 800

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   821 KERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEV 900
Cdd:TIGR02169  801 SKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDL 880

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   901 EAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVK--SLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQkKE 978
Cdd:TIGR02169  881 ESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKrlSELKAKLEALEEELSEIEDPKGEDEEIPEEELSLEDVQ-AE 959

                          810       820       830       840
                   ....*....|....*....|....*....|....*....|....*....
gi 530372322   979 IEILTQKLSAKEDSIHILNEEYET---KFKNQEKKMEKVKQKAKEMQET 1024
Cdd:TIGR02169  960 LQRVEEEIRALEPVNMLAIQEYEEvlkRLDELKEKRAKLEEERKAILER 1008
mukB PRK04863
chromosome partition protein MukB;
192-459 2.98e-06

chromosome partition protein MukB;


Pssm-ID: 235316 [Multi-domain]  Cd Length: 1486  Bit Score: 53.04  E-value: 2.98e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  192 EQLIQRLRRMERSLSSYRGKYSELVTAYQMLQREKKKLQGILSQS---QDKSL-RRIAELREELQMDQQAKKHLQ----- 262
Cdd:PRK04863  840 RQLNRRRVELERALADHESQEQQQRSQLEQAKEGLSALNRLLPRLnllADETLaDRVEEIREQLDEAEEAKRFVQqhgna 919

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  263 ----EEFDASLEEKDQYISVLQTQVSLLKQRLRNGPMNVDVLKPLPQlepQAEVFTKEENPESDGEpvvEDGTSvktlET 338
Cdd:PRK04863  920 laqlEPIVSVLQSDPEQFEQLKQDYQQAQQTQRDAKQQAFALTEVVQ---RRAHFSYEDAAEMLAK---NSDLN----EK 989

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  339 LQQRVKRQENLLKRCKETIQSHKEQCTL-------LTSEKEALQEQLDERLQELEKI--------KDLHMAEKTKLITQL 403
Cdd:PRK04863  990 LRQRLEQAEQERTRAREQLRQAQAQLAQynqvlasLKSSYDAKRQMLQELKQELQDLgvpadsgaEERARARRDELHARL 1069

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 530372322  404 RDAKNLIEQLEQdkgmviaetkrqmheTLEMKEEEIAQLRSRIKQMTTQGEELREQ 459
Cdd:PRK04863 1070 SANRSRRNQLEK---------------QLTFCEAEMDNLTKKLRKLERDYHEMREQ 1110
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 794-1260 3.92e-06

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 52.33  E-value: 3.92e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   794 IIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYE 873
Cdd:TIGR04523   79 ILEQQIKDLNDKLKKNKDKINKLNSDLSKINSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLN 158

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   874 EQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDA---------HKIQVQDLMQ----QLEKQNSEMEQKVKSLT 940
Cdd:TIGR04523  159 NKYNDLKKQKEELENELNLLEKEKLNIQKNIDKIKNKLLKlelllsnlkKKIQKNKSLEsqisELKKQNNQLKDNIEKKQ 238

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   941 QVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKkEIEILTQKLSAKEDSIHILNEEYE---------------TKFK 1005
Cdd:TIGR04523  239 QEINEKTTEISNTQTQLNQLKDEQNKIKKQLSEKQK-ELEQNNKKIKELEKQLNQLKSEISdlnnqkeqdwnkelkSELK 317

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1006 NQEKKMEKVKQKAKEMQETLKKkLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISdavsrletnQKEQIE 1085
Cdd:TIGR04523  318 NQEKKLEEIQNQISQNNKIISQ-LNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQS---------YKQEIK 387

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1086 SLtEVHRRELNDVISIwEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNE 1165
Cdd:TIGR04523  388 NL-ESQINDLESKIQN-QEKLNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDNTRES 465

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1166 LQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKS 1245
Cdd:TIGR04523  466 LETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLED 545

                          490
                   ....*....|....*
gi 530372322  1246 SHEKSNKSLEDKSLE 1260
Cdd:TIGR04523  546 ELNKDDFELKKENLE 560
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 923-1755 5.87e-06

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 51.90  E-value: 5.87e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   923 QQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYET 1002
Cdd:pfam02463  169 RKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRD 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1003 KfkNQEKKMEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKE 1082
Cdd:pfam02463  249 E--QEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKA 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1083 QIESLTEVHRRELndvISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTT 1162
Cdd:pfam02463  327 EKELKKEKEEIEE---LEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEE 403

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1163 LNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQS 1242
Cdd:pfam02463  404 EKEAQLLLELARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQ 483

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1243 LKSSHEKSNKSLEDKSLEFKKLSEELAIQLDICCKKTEALLEAKTNELINISSSKTNAILSRISHCQHRTTKVKEALLIK 1322
Cdd:pfam02463  484 EQLELLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEER 563

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1323 TCTVSELEAQLRQLTEEQnTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLKKE 1402
Cdd:pfam02463  564 QKLVRALTELPLGARKLR-LLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAK 642

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1403 LSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKE 1482
Cdd:pfam02463  643 AKESGLRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEEL 722

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1483 KISALEQVDDWSNKFSEWKKKAQSRFTQhqntvKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKS 1562
Cdd:pfam02463  723 LADRVQEAQDKINEELKLLKQKIDEEEE-----EEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLK 797

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1563 KMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKI 1642
Cdd:pfam02463  798 AQEEELRALEEELKEEAELLEEEQLLIEQEEKIKEEELEELALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEE 877

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1643 LTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQ-----KIAAIKKQLLSQMEEK 1717
Cdd:pfam02463  878 ELEEQKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEEEpeellLEEADEKEKEENNKEE 957

                          810       820       830
                   ....*....|....*....|....*....|....*...
gi 530372322  1718 EEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVES 1755
Cdd:pfam02463  958 EEERNKRLLLAKEELGKVNLMAIEEFEEKEERYNKDEL 995
PTZ00121 PTZ00121
MAEBL; Provisional
 771-1282 6.01e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 52.07  E-value: 6.01e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  771 KMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQ 850
Cdd:PTZ00121 1230 KKAEEAKKDAEEAKKAEEERNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEKKKADEAKK 1309

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  851 ASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKdvctELDAHKIQVQDLMQQLEKQNS 930
Cdd:PTZ00121 1310 KAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEE----KAEAAEKKKEEAKKKADAAKK 1385

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  931 EMEQKVKSlTQVYESKLEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKK 1010
Cdd:PTZ00121 1386 KAEEKKKA-DEAKKKAEEDKKKADELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKK 1464

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1011 MEKVKQKAKEMQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQK-EQIESLTE 1089
Cdd:PTZ00121 1465 KAEEAKKADEAKKKAEEAKKADEAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKaDEAKKAEE 1544

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1090 VHRRElndviSIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQ 1169
Cdd:PTZ00121 1545 KKKAD-----ELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEAK 1619

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1170 LK----QKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQlveLKMLAEEDKRKVSELTSKLKTTDEEFQSLKS 1245
Cdd:PTZ00121 1620 IKaeelKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAE---EAKKAEEDKKKAEEAKKAEEDEKKAAEALKK 1696

                         490       500       510
                  ....*....|....*....|....*....|....*....
gi 530372322 1246 SHEKSNKS--LEDKSLEFKKLSEELAIQLDICCKKTEAL 1282
Cdd:PTZ00121 1697 EAEEAKKAeeLKKKEAEEKKKAEELKKAEEENKIKAEEA 1735
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1457-2189 8.01e-06

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 51.61  E-value: 8.01e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1457 QYDEEK---CELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWK----KKAQSRFTQHQNTVKELQIQLELKSKEA 1529
Cdd:TIGR02169  167 EFDRKKekaLEELEEVEENIERLDLIIDEKRQQLERLRREREKAERYQallkEKREYEGYELLKEKEALERQKEAIERQL 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1530 YEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESN----LETELKSQTARIMELEDHITQKTIEIESLNEVLKN 1605
Cdd:TIGR02169  247 ASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEeqlrVKEKIGELEAEIASLERSIAEKERELEDAEERLAK 326

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1606 YNQQ---KDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLS---VKSKEEELKA 1679
Cdd:TIGR02169  327 LEAEidkLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKlekLKREINELKR 406

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1680 LEDRLESES---AAKLAELKRKAEQKIAAIKkQLLSQMEEKEEQYKKGT-------------ESHLSELNTKLQEREREV 1743
Cdd:TIGR02169  407 ELDRLQEELqrlSEELADLNAAIAGIEAKIN-ELEEEKEDKALEIKKQEwkleqlaadlskyEQELYDLKEEYDRVEKEL 485

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1744 HILEEKLKSVESSQSetLIVPRSAKNVAAyTEQEEADSQGcVQKTYEEKISVLQRNLTEKE----KLLQRVGQEKEETVS 1819
Cdd:TIGR02169  486 SKLQRELAEAEAQAR--ASEERVRGGRAV-EEVLKASIQG-VHGTVAQLGSVGERYATAIEvaagNRLNNVVVEDDAVAK 561

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1820 SHFEMRCQYQ-ERLIKLEHAEAKQHEDQSMIGHLQE------ELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENVFDD 1892
Cdd:TIGR02169  562 EAIELLKRRKaGRATFLPLNKMRDERRDLSILSEDGvigfavDLVEFDPKYEPAFKYVFGDTLVVEDIEAARRLMGKYRM 641

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1893 VQktlqekeLTCQILEQK--IKELDSCLVRQKEVHRVEMEELTSKYEKLQALQqmdgrnkptelleenteekskshlvqp 1970
Cdd:TIGR02169  642 VT-------LEGELFEKSgaMTGGSRAPRGGILFSRSEPAELQRLRERLEGLK--------------------------- 687

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1971 KLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQELEILK------KEYDQEREE----------KI 2034
Cdd:TIGR02169  688 RELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEeleedlSSLEQEIENvkselkeleaRI 767

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  2035 KQEQEDL---ELKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLESHQE------ETNQLLKKIAEKDD 2105
Cdd:TIGR02169  768 EELEEDLhklEEALNDLEARLSHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEkeylekEIQELQEQRIDLKE 847

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  2106 DLKRTAKRYEEI------LDAREEEMTAKVRDLQTQLEELQKKYQ----QKLEQEENPGNDNTQLAQKTTLISDSKLKEQ 2175
Cdd:TIGR02169  848 QIKSIEKEIENLngkkeeLEEELEELEAALRDLESRLGDLKKERDeleaQLRELERKIEELEAQIEKKRKRLSELKAKLE 927

                          810
                   ....*....|....
gi 530372322  2176 EFREQIHNLEDRLK 2189
Cdd:TIGR02169  928 ALEEELSEIEDPKG 941
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 354-1270 8.63e-06

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 51.20  E-value: 8.63e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   354 KETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLhmaEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLE 433
Cdd:TIGR00606  151 NNVIFCHQEDSNWPLSEGKALKQKFDEIFSATRYIKAL---ETLRQVRQTQGQKVQEHQMELKYLKQYKEKACEIRDQIT 227

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   434 MKEEEIAQLRSRIKQMTTQGEELREQKEKSE--RAAFEELEKALSTAQKTEEARRKLKAEM-----------DEQIKTIE 500
Cdd:TIGR00606  228 SKEAQLESSREIVKSYENELDPLKNRLKEIEhnLSKIMKLDNEIKALKSRKKQMEKDNSELelkmekvfqgtDEQLNDLY 307

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   501 -------KTSEEERISLQQELSRVKQEVVDVMKKSSEEQIA------KLQKLHEKELARKEQELTKKLQTREREFQEQMK 567
Cdd:TIGR00606  308 hnhqrtvREKERELVDCQRELEKLNKERRLLNQEKTELLVEqgrlqlQADRHQEHIRARDSLIQSLATRLELDGFERGPF 387

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   568 VALEKSQSEYLKIS-QEKEQQESLALEELELQKKAILTESENKLRDlqqeAETYRTRILELESSLeksLQENKNQSKDLA 646
Cdd:TIGR00606  388 SERQIKNFHTLVIErQEDEAKTAAQLCADLQSKERLKQEQADEIRD----EKKGLGRTIELKKEI---LEKKQEELKFVI 460

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   647 VHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEM 726
Cdd:TIGR00606  461 KELQQLEGSSDRILELDQELRKAERELSKAEKNSLTETLKKEVKSLQNEKADLDRKLRKLDQEMEQLNHHTTTRTQMEML 540

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   727 NEKTLEKLD----------VKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELeAKMDEQKNHHQQQVDSiIK 796
Cdd:TIGR00606  541 TKDKMDKDEqirkiksrhsDELTSLLGYFPNKKQLEDWLHSKSKEINQTRDRLAKLNKEL-ASLEQNKNHINNELES-KE 618

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   797 EHEVSIQR------TEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTK 870
Cdd:TIGR00606  619 EQLSSYEDklfdvcGSQDEESDLERLKEEIEKSSKQRAMLAGATAVYSQFITQLTDENQSCCPVCQRVFQTEAELQEFIS 698

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   871 AYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMeQKVKSLTQVYESKLEDG 950
Cdd:TIGR00606  699 DLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELRNKLQKVNRDI-QRLKNDIEEQETLLGTI 777

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   951 NKEQEQTKQILVEKEnmILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEK--KMEKVKQKAKEMQetlkkK 1028
Cdd:TIGR00606  778 MPEEESAKVCLTDVT--IMERFQMELKDVERKIAQQAAKLQGSDLDRTVQQVNQEKQEKqhELDTVVSKIELNR-----K 850

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1029 LLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANsagisdavSRLETNQKEQIESLTEV-HRRELNDVISIWEKKLN 1107
Cdd:TIGR00606  851 LIQDQQEQIQHLKSKTNELKSEKLQIGTNLQRRQQFE--------EQLVELSTEVQSLIREIkDAKEQDSPLETFLEKDQ 922

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1108 QQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQ-DTTLNELQEQLKQKSAHVNSLAQDetk 1186
Cdd:TIGR00606  923 QEKEELISSKETSNKKAQDKVNDIKEKVKNIHGYMKDIENKIQDGKDDYLKQkETELNTVNAQLEECEKHQEKINED--- 999

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1187 lkahLEKLEVDLNKSLKENTFLQEQLVELKMlaeedKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSE 1266
Cdd:TIGR00606 1000 ----MRLMRQDIDTQKIQERWLQDNLTLRKR-----ENELKEVEEELKQHLKEMGQMQVLQMKQEHQKLEENIDLIKRNH 1070


                   ....
gi 530372322  1267 ELAI 1270
Cdd:TIGR00606 1071 VLAL 1074
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 193-734 1.17e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 50.71  E-value: 1.17e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  193 QLIQRLRRMERSLSSYRGKYSELVTAYQMLQREKKKLQgilsQSQDKSLRRIAELREELQMDQQAKKHLQEEFDASLEEK 272
Cdd:COG1196   292 ELLAELARLEQDIARLEERRRELEERLEELEEELAELE----EELEELEEELEELEEELEEAEEELEEAEAELAEAEEAL 367

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  273 DQYISVLQTQVSLLKQRLRngpmnvDVLKPLPQLEPQAEVFTKEENPESDGEpvVEDGTSVKTLETLQQRVKRQENLLKR 352
Cdd:COG1196   368 LEAEAELAEAEEELEELAE------ELLEALRAAAELAAQLEELEEAEEALL--ERLERLEEELEELEEALAELEEEEEE 439

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  353 CKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETL 432
Cdd:COG1196   440 EEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGL 519

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  433 EMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQ 512
Cdd:COG1196   520 RGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGA 599

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  513 ELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALE-KSQSEYLKISQEKEQQESLA 591
Cdd:COG1196   600 AVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAgGSLTGGSRRELLAALLEAEA 679

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  592 LEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTEL 671
Cdd:COG1196   680 ELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEP 759

                         490       500       510       520       530       540       550
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 530372322  672 ESLKHQQdalwtEKLQVLKQQYQT----------EMEKLREKCE---QEKETLLKDKEIIFQAhIEEMNEKTLEKL 734
Cdd:COG1196   760 PDLEELE-----RELERLEREIEAlgpvnllaieEYEELEERYDflsEQREDLEEARETLEEA-IEEIDRETRERF 829
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 491-1201 1.23e-05

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 50.89  E-value: 1.23e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   491 EMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIaklqklhekelarkEQELTKKLQTREREFQEQMKVAL 570
Cdd:pfam15921   82 EYSHQVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQEMQM--------------ERDAMADIRRRESQSQEDLRNQL 147

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   571 EKSQSEYLKISQEKEQQESLALEELELQKKAILTEsENKLRDLqqeaetyRTRILELESSLEKSLQENKNQSkdlAVHLE 650
Cdd:pfam15921  148 QNTVHELEAAKCLKEDMLEDSNTQIEQLRKMMLSH-EGVLQEI-------RSILVDFEEASGKKIYEHDSMS---TMHFR 216

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   651 AeknkHNKEITVMVEKHKTELESLKHQQDALwTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIifqaHIEEMNEKT 730
Cdd:pfam15921  217 S----LGSAISKILRELDTEISYLKGRIFPV-EDQLEALKSESQNKIELLLQQHQDRIEQLISEHEV----EITGLTEKA 287

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   731 LEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQEL-EAKMDEQKNHHQQQVDSIIKEHEVSIQRTEK-- 807
Cdd:pfam15921  288 SSARSQANSIQSQLEIIQEQARNQNSMYMRQLSDLESTVSQLRSELrEAKRMYEDKIEELEKQLVLANSELTEARTERdq 367

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   808 ------ALKDQINQLELLLKERDKHLKEHQAH--------------VENLEADIKRSEGELQQASAKLDVFQSYQSATHE 867
Cdd:pfam15921  368 fsqesgNLDDQLQKLLADLHKREKELSLEKEQnkrlwdrdtgnsitIDHLRRELDDRNMEVQRLEALLKAMKSECQGQME 447

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   868 QTKAY----EEQLAQLQQKLLDLETERILLTKQVAEVEAQKkdvcTELDAHKIQVQDLMQQLEKQNSEME------QKVK 937
Cdd:pfam15921  448 RQMAAiqgkNESLEKVSSLTAQLESTKEMLRKVVEELTAKK----MTLESSERTVSDLTASLQEKERAIEatnaeiTKLR 523

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   938 SLTQVYESKLEDGNKEQEQTKQILVEKENMILQMREgQKKEIEILTQKLsakEDSIHILNEEYETKFKNQEKKMEKVK-- 1015
Cdd:pfam15921  524 SRVDLKLQELQHLKNEGDHLRNVQTECEALKLQMAE-KDKVIEILRQQI---ENMTQLVGQHGRTAGAMQVEKAQLEKei 599

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1016 -------QKAKEMQETLKKKLLDQEAKLKK-ELENTALELSQKE--------KQFNAKMLEMAQANSAGISDAVSRLET- 1078
Cdd:pfam15921  600 ndrrlelQEFKILKDKKDAKIRELEARVSDlELEKVKLVNAGSErlravkdiKQERDQLLNEVKTSRNELNSLSEDYEVl 679

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1079 -----NQKEQIESLTEVHRRELNDVISIWEKKLNQ-QAEELQEIHEI--------QLQEKEQEVAELKQKILLFGCEKEE 1144
Cdd:pfam15921  680 krnfrNKSEEMETTTNKLKMQLKSAQSELEQTRNTlKSMEGSDGHAMkvamgmqkQITAKRGQIDALQSKIQFLEEAMTN 759

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*..
gi 530372322  1145 MNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKS 1201
Cdd:pfam15921  760 ANKEKHFLKEEKNKLSQELSTVATEKNKMAGELEVLRSQERRLKEKVANMEVALDKA 816
GRIP pfam01465
GRIP domain; The GRIP (golgin-97, RanBP2alpha,Imh1p and p230/golgin-245) domain is found in ...
 2221-2260 1.23e-05

GRIP domain; The GRIP (golgin-97, RanBP2alpha,Imh1p and p230/golgin-245) domain is found in many large coiled-coil proteins. It has been shown to be sufficient for targeting to the Golgi. The GRIP domain contains a completely conserved tyrosine residue. At least some of these domains have been shown to bind to GTPase Arl1, see structures in.


Pssm-ID: 460221 [Multi-domain]  Cd Length: 44  Bit Score: 44.27  E-value: 1.23e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|...
gi 530372322  2221 TEFEYLRKVLFEYMMGRET---KTMAKVITTVLKFPDDQTQKI 2260
Cdd:pfam01465    2 ANLEYLKNVLLQFLESKESserKQLLPVIATLLKFSPEEEQKI 44
PRK05771 PRK05771
V-type ATP synthase subunit I; Validated
 1514-1742 1.26e-05

V-type ATP synthase subunit I; Validated


Pssm-ID: 235600 [Multi-domain]  Cd Length: 646  Bit Score: 50.70  E-value: 1.26e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1514 TVKELQ----IQLELKSKEayEKDEQINLLKEELDQQNKRFDCLKGEME----DDKSKMEKKESNLETELKSQTARIMEL 1585
Cdd:PRK05771   21 VLEALHelgvVHIEDLKEE--LSNERLRKLRSLLTKLSEALDKLRSYLPklnpLREEKKKVSVKSLEELIKDVEEELEKI 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1586 EDHITQKTIEIESLNEVLKNYNQQKDIehkelVQKLQHF----QELGEEKD-----NRVKEAEEKILTLENQVYsmKAEL 1656
Cdd:PRK05771   99 EKEIKELEEEISELENEIKELEQEIER-----LEPWGNFdldlSLLLGFKYvsvfvGTVPEDKLEELKLESDVE--NVEY 171

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1657 ETKKKELEHVNLSVKSK-----EEELKALE-DRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLS 1730
Cdd:PRK05771  172 ISTDKGYVYVVVVVLKElsdevEEELKKLGfERLELEEEGTPSELIREIKEELEEIEKERESLLEELKELAKKYLEELLA 251

                         250
                  ....*....|..
gi 530372322 1731 ELNTKLQERERE 1742
Cdd:PRK05771  252 LYEYLEIELERA 263
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1516-2185 1.59e-05

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 50.36  E-value: 1.59e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1516 KELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIE 1595
Cdd:pfam02463  207 KKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEE 286

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1596 IESLNEVLKNYNQQKDIehkelvqKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEE 1675
Cdd:pfam02463  287 ELKLLAKEEEELKSELL-------KLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEELEKELKELEIKREAEEEEEE 359

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1676 ELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQykkgteshlSELNTKLQEREREVHILEEKLKSVES 1755
Cdd:pfam02463  360 ELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEE---------KEAQLLLELARQLEDLLKEEKKEELE 430

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1756 SQSETLIVPRSAKNVAAyTEQEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKL 1835
Cdd:pfam02463  431 ILEEEEESIELKQGKLT-EEKEELEKQELKLLKDELELKKSEDLLKETQLVKLQEQLELLLSRQKLEERSQKESKARSGL 509

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1836 EHAEAkqhedQSMIGHLQEELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKELD 1915
Cdd:pfam02463  510 KVLLA-----LIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLI 584

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1916 SCLVRQKEVHRVEMEELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQ 1995
Cdd:pfam02463  585 PKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEV 664

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1996 KLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIKETI 2075
Cdd:pfam02463  665 KASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQK 744

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  2076 NKAQEVEAELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEENPGN 2155
Cdd:pfam02463  745 IDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLI 824

                          650       660       670
                   ....*....|....*....|....*....|
gi 530372322  2156 DNTQLAQKTTLISDSKLKEQEFREQIHNLE 2185
Cdd:pfam02463  825 EQEEKIKEEELEELALELKEEQKLEKLAEE 854
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1633-2152 1.68e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 50.45  E-value: 1.68e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1633 NRVKEAEEKILT----LENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLEsesaaklaELKRKAEqKIAAIKK 1708
Cdd:PRK03918  175 KRRIERLEKFIKrtenIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVK--------ELEELKE-EIEELEK 245

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1709 QLlsqmeEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADSQGcvQKT 1788
Cdd:PRK03918  246 EL-----ESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDELREIEKR--LSR 318

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1789 YEEKISVLQRNLTEKEKLLQRVGQEKEETVsshfemrcQYQERLIKLEhaeaKQHEDQSMIGHLQEELEEKNKKYSLIVA 1868
Cdd:PRK03918  319 LEEEINGIEERIKELEEKEERLEELKKKLK--------ELEKRLEELE----ERHELYEEAKAKKEELERLKKRLTGLTP 386

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1869 QHVEKEGgKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKELDS----CLVRQKEVHRVEMEELTSKY-------- 1936
Cdd:PRK03918  387 EKLEKEL-EELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKakgkCPVCGRELTEEHRKELLEEYtaelkrie 465

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1937 EKLQALQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEF----KLAGAEREKQKLGKEIVRLQKDLRMLR 2012
Cdd:PRK03918  466 KELKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLKKynleELEKKAEEYEKLKEKLIKLKGEIKSLK 545

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 2013 KEhQQELEILKKEYDQEREEKIKQEQEDLELKHNstLKQLMREFNTQLAQKEQELEMTIKETIN-----KAQEVEAELLE 2087
Cdd:PRK03918  546 KE-LEKLEELKKKLAELEKKLDELEEELAELLKE--LEELGFESVEELEERLKELEPFYNEYLElkdaeKELEREEKELK 622

                         490       500       510       520       530       540
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 530372322 2088 SHQEETNQLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEEN 2152
Cdd:PRK03918  623 KLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELREEYLELSRELAGLRAELEELEK 687
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
350-577 1.74e-05

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 50.30  E-value: 1.74e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  350 LKRCKETIQSHKEQCTLLTSEKEALQE--QLDERLQELEKIKdlHMAEKTKLITQLRDAKNLIEQLEQDkgmviaetkrq 427
Cdd:COG4913   237 LERAHEALEDAREQIELLEPIRELAERyaAARERLAELEYLR--AALRLWFAQRRLELLEAELEELRAE----------- 303

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  428 mhetLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEER 507
Cdd:COG4913   304 ----LARLEAELERLEARLDALREELDELEAQIRGNGGDRLEQLEREIERLERELEERERRRARLEALLAALGLPLPASA 379

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  508 islqQELSRVKQEVVDVMKKSSEEQIAKLQKLHekELARKEQELTKKLQTREREFQeqmkvALEKSQSEY 577
Cdd:COG4913   380 ----EEFAALRAEAAALLEALEEELEALEEALA--EAEAALRDLRRELRELEAEIA-----SLERRKSNI 438
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 611-1172 1.76e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 50.32  E-value: 1.76e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  611 RDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLK 690
Cdd:COG1196   216 RELKEELKELEAELLLLKLRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLA 295

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  691 QQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTD 770
Cdd:COG1196   296 ELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELA 375

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  771 KMKQELEAKMDEQKNHHQQQVDsiIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQ 850
Cdd:COG1196   376 EAEEELEELAEELLEALRAAAE--LAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAE 453

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  851 ASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVcteLDAHKIQVQDLMQQLEKQNS 930
Cdd:COG1196   454 LEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGV---KAALLLAGLRGLAGAVAVLI 530

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  931 EMEQKVKSLTQVYESKLEDGNkeQEQTKQILVEKENMILQMREGQKKEIEILTQK-LSAKEDSIHILNEEYETKFKNQEK 1009
Cdd:COG1196   531 GVEAAYEAALEAALAAALQNI--VVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRaRAALAAALARGAIGAAVDLVASDL 608

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1010 KMEKVKQKAKEMQ---ETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKmLEMAQANSAGISDAVSRLETNQKEQIES 1086
Cdd:COG1196   609 READARYYVLGDTllgRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAG-GSLTGGSRRELLAALLEAEAELEELAER 687

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1087 LTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFgcEKEEMNKEITWLKEEGVKQDTTLNEL 1166
Cdd:COG1196   688 LAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLE--ELLEEEELLEEEALEELPEPPDLEEL 765


                  ....*.
gi 530372322 1167 QEQLKQ 1172
Cdd:COG1196   766 ERELER 771
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1636-1944 1.83e-05

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 50.07  E-value: 1.83e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1636 KEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLE--SESAAKLAELKRKAEQKIAAIKKQLLSQ 1713
Cdd:TIGR02169  670 RSEPAELQRLRERLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGeiEKEIEQLEQEEEKLKERLEELEEDLSSL 749

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1714 MEEKEEQykkgtESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIvprsaknvaaYTEQEEADSQGCVQKTYEEKI 1793
Cdd:TIGR02169  750 EQEIENV-----KSELKELEARIEELEEDLHKLEEALNDLEARLSHSRI----------PEIQAELSKLEEEVSRIEARL 814

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1794 SVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEK 1873
Cdd:TIGR02169  815 REIEQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLGDLKKERDEL 894

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 530372322  1874 EGGKNNIQAKQN-LENVFDDVQKTLQEKELTCQILEQKIKELDSCLVRQKEVHRVEMeELTSKYEKLQALQQ 1944
Cdd:TIGR02169  895 EAQLRELERKIEeLEAQIEKKRKRLSELKAKLEALEEELSEIEDPKGEDEEIPEEEL-SLEDVQAELQRVEE 965
Mplasa_alph_rch TIGR04523
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ...
 1152-1777 2.01e-05

helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.


Pssm-ID: 275316 [Multi-domain]  Cd Length: 745  Bit Score: 50.02  E-value: 2.01e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1152 LKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTS 1231
Cdd:TIGR04523   24 YKNIANKQDTEEKQLEKKLKTIKNELKNKEKELKNLDKNLNKDEEKINNSNNKIKILEQQIKDLNDKLKKNKDKINKLNS 103

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1232 KLKTTDEEFQSLKSshEKSNKSLEDKSLE-FKKLSEELAIQLDICCKKTEALLEAKTNELINISSSKT------NAILSR 1304
Cdd:TIGR04523  104 DLSKINSEIKNDKE--QKNKLEVELNKLEkQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEelenelNLLEKE 181

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1305 ISHCQHRTTKVKEALLIKTCTVSELEAqlrqLTEEQNTLNIsfqqathQLEEKENQIKSMKADIESLVTEKEALQKEGGN 1384
Cdd:TIGR04523  182 KLNIQKNIDKIKNKLLKLELLLSNLKK----KIQKNKSLES-------QISELKKQNNQLKDNIEKKQQEINEKTTEISN 250

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1385 QQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSIS------LSEKEAAISSLRKQY 1458
Cdd:TIGR04523  251 TQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSEISDLNNQKEQDWNkelkseLKNQEKKLEEIQNQI 330

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1459 DEEK---CELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQN---TVKELQIQLELKSKEAYEK 1532
Cdd:TIGR04523  331 SQNNkiiSQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNlesQINDLESKIQNQEKLNQQK 410

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1533 DEQINLLKEELDQQNKRFDCLKGEMEDDKSKMekkeSNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDI 1612
Cdd:TIGR04523  411 DEQIKKLQQEKELLEKEIERLKETIIKNNSEI----KDLTNQDSVKELIIKNLDNTRESLETQLKVLSRSINKIKQNLEQ 486

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1613 EHKELVQKLQHFQELGEEKdnrvKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKL 1692
Cdd:TIGR04523  487 KQKELKSKEKELKKLNEEK----KELEEKVKDLTKKISSLKEKIEKLESEKKEKESKISDLEDELNKDDFELKKENLEKE 562

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1693 AELKRKAEQKIAAIKKQLLSQMEEKEEQYKKgTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAA 1772
Cdd:TIGR04523  563 IDEKNKEIEELKQTQKSLKKKQEEKQELIDQ-KEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKN 641


                   ....*
gi 530372322  1773 YTEQE 1777
Cdd:TIGR04523  642 KLKQE 646
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 242-552 2.68e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 49.67  E-value: 2.68e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   242 RRIAELREELQMDQQAKKHLQEEFDASLEEKDQyisvLQTQVSLLKQRLRngpmnvDVLKPLPQLEPQAEVFTKEEnpes 321
Cdd:TIGR02168  677 REIEELEEKIEELEEKIAELEKALAELRKELEE----LEEELEQLRKELE------ELSRQISALRKDLARLEAEV---- 742

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   322 dgepvvedgtsvktlETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLit 401
Cdd:TIGR02168  743 ---------------EQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREAL-- 805

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   402 qlrDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEEL---REQKEKSERAAFEELEKALSTA 478
Cdd:TIGR02168  806 ---DELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLaaeIEELEELIEELESELEALLNER 882

                          250       260       270       280       290       300       310
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 530372322   479 QKTEEARRKLKAEMDEQIKTIEKTsEEERISLQQELSRVKQEVVDVmkkSSEEQIAKLQKLHEKELARKEQELT 552
Cdd:TIGR02168  883 ASLEEALALLRSELEELSEELREL-ESKRSELRRELEELREKLAQL---ELRLEGLEVRIDNLQERLSEEYSLT 952
PRK12704 PRK12704
phosphodiesterase; Provisional
 1604-1717 3.05e-05

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 49.01  E-value: 3.05e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1604 KNYNQQKDIEHKELVQKL--QHFQELgEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALE 1681
Cdd:PRK12704   52 EAIKKEALLEAKEEIHKLrnEFEKEL-RERRNELQKLEKRLLQKEENLDRKLELLEKREEELEKKEKELEQKQQELEKKE 130

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 530372322 1682 DRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEK 1717
Cdd:PRK12704  131 EELEELIEEQLQELERISGLTAEEAKEILLEKVEEE 166
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1504-1727 3.33e-05

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 48.67  E-value: 3.33e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1504 AQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLET---ELKSQTA 1580
Cdd:COG3883    14 ADPQIQAKQKELSELQAELEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEErreELGERAR 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1581 RIMELEDHITQKTI--EIESLNEVLKNYNQQKDIE--HKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAEL 1656
Cdd:COG3883    94 ALYRSGGSVSYLDVllGSESFSDFLDRLSALSKIAdaDADLLEELKADKAELEAKKAELEAKLAELEALKAELEAAKAEL 173

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 530372322 1657 ETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTES 1727
Cdd:COG3883   174 EAQQAEQEALLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA 244
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
1325-1860 3.42e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 49.27  E-value: 3.42e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1325 TVSELEAQLRQLTEEQNTLNISFQQATHQL----------EEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKES 1394
Cdd:PRK02224  207 RLNGLESELAELDEEIERYEEQREQARETRdeadevleehEERREELETLEAEIEDLRETIAETEREREELAEEVRDLRE 286

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1395 CITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQL-QNSISLSEKEAAISSLRKQYDEekceLLDQVQDLS 1473
Cdd:PRK02224  287 RLEELEEERDDLLAEAGLDDADAEAVEARREELEDRDEELRDRLeECRVAAQAHNEEAESLREDADD----LEERAEELR 362

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1474 FKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKE-ELDQQNKRFDC 1552
Cdd:PRK02224  363 EEAAELESELEEAREAVEDRREEIEELEEEIEELRERFGDAPVDLGNAEDFLEELREERDELREREAElEATLRTARERV 442

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1553 LKGEMEDDKSK-----MEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHK--ELVQKLQHFQ 1625
Cdd:PRK02224  443 EEAEALLEAGKcpecgQPVEGSPHVETIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAEDRieRLEERREDLE 522

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1626 ELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLEsESAAKLAELKRKAEqkiaa 1705
Cdd:PRK02224  523 ELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAELNSKLA-ELKERIESLERIRT----- 596

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1706 ikkqLLSQMEEKEEQYKKGTE--SHLSELNTKLQEREREvhiLEEKLKSVESSQSETLIvprsaknvaayteqEEADSQG 1783
Cdd:PRK02224  597 ----LLAAIADAEDEIERLREkrEALAELNDERRERLAE---KRERKRELEAEFDEARI--------------EEAREDK 655

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1784 CVQKTYEEKISVLQRNLTEKE-KLLQRVGQEKEE--TVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGHLQEELEEKN 1860
Cdd:PRK02224  656 ERAEEYLEQVEEKLDELREERdDLQAEIGAVENEleELEELRERREALENRVEALEALYDEAEELESMYGDLRAELRQRN 735
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1391-2125 3.48e-05

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 49.20  E-value: 3.48e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1391 EKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCELLDQVQ 1470
Cdd:pfam02463  206 AKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQELLRDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQE 285

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1471 DLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLE--LKSKEAYEKDEQINLLKEELDQQNK 1548
Cdd:pfam02463  286 EELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEKELKKEKEEIEelEKELKELEIKREAEEEEEEELEKLQ 365

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1549 RFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLknyNQQKDIEHKELVQKLQHFQELG 1628
Cdd:pfam02463  366 EKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQLLLELARQLEDL---LKEEKKEELEILEEEEESIELK 442

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1629 EEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEhvnlSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKK 1708
Cdd:pfam02463  443 QGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQ----LVKLQEQLELLLSRQKLEERSQKESKARSGLKVLLALIKD 518

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1709 QLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADsqgcvqkt 1788
Cdd:pfam02463  519 GVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKLVRALTELPLGARKLRLLIPKLKLP-------- 590

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1789 yEEKISVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGHLQEELEEKNKKYSLIVA 1868
Cdd:pfam02463  591 -LKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEGILKDTELTKLKESAKAKESGLRKGVSLEEGLAEKSEVKASLS 669

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1869 QHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKLQALQQMDGR 1948
Cdd:pfam02463  670 ELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRVQEAQDKINEELKLLKQKIDEEE 749

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1949 NKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQ 2028
Cdd:pfam02463  750 EEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEKLKVEEEKEEKLKAQEEELRALEEELKEEAELLEEEQLLIEQEEK 829

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  2029 EREEKIKQEQEDLEL-----KHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLESHQEETNQLLKKIAEK 2103
Cdd:pfam02463  830 IKEEELEELALELKEeqkleKLAEEELERLEEEITKEELLQELLLKEEELEEQKLKDELESKEEKEKEEKKELEEESQKL 909

                          730       740
                   ....*....|....*....|..
gi 530372322  2104 DDDLKRTAKRYEEILDAREEEM 2125
Cdd:pfam02463  910 NLLEEKENEIEERIKEEAEILL 931
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
376-939 4.84e-05

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 48.91  E-value: 4.84e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  376 EQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHEtLEMKEEEIAQLRSRIKQMTTQGEE 455
Cdd:PRK03918  161 ENAYKNLGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSE-LPELREELEKLEKEVKELEELKEE 239

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  456 LREQKEK--SERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIE--KTSEEERISLQQELSRVKQEVVDVMKKSS-- 529
Cdd:PRK03918  240 IEELEKEleSLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKelKEKAEEYIKLSEFYEEYLDELREIEKRLSrl 319

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  530 EEQIAKLQKLHEK--ELARKEQELTKKLQTREREFQEqmkvaLEKSQSEYLKISQEKEQqeslaleeLELQKKAILTESE 607
Cdd:PRK03918  320 EEEINGIEERIKEleEKEERLEELKKKLKELEKRLEE-----LEERHELYEEAKAKKEE--------LERLKKRLTGLTP 386

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  608 NKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITV---MVEKHKTELESLKHQQDALWTE 684
Cdd:PRK03918  387 EKLEKELEELEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCgreLTEEHRKELLEEYTAELKRIEK 466

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  685 KLQVLKQQyqteMEKLREKCEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKAR-HKLEEELS 763
Cdd:PRK03918  467 ELKEIEEK----ERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKlIKLKGEIK 542

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  764 VLKDQTDKmKQELE---AKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKhLKEHQAHVENLEAD 840
Cdd:PRK03918  543 SLKKELEK-LEELKkklAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEYLE-LKDAEKELEREEKE 620

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  841 IKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERilLTKQVAEVEAQKKdvctELDAHKIQVQD 920
Cdd:PRK03918  621 LKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELREEYLE--LSRELAGLRAELE----ELEKRREEIKK 694

                         570
                  ....*....|....*....
gi 530372322  921 LMQQLEKQNSEMEQKVKSL 939
Cdd:PRK03918  695 TLEKLKEELEEREKAKKEL 713
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 511-839 5.06e-05

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 48.58  E-value: 5.06e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   511 QQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQeltkkLQTREREFQEQMKVALEKSQsEYLKISQEKEQQESL 590
Cdd:pfam17380  290 QEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKARQAE-----MDRQAAIYAEQERMAMERER-ELERIRQEERKRELE 363

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   591 ALEElelQKKAILTESENKLRDLQQEAETYRTRIL-ELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEitvmvEKHKT 669
Cdd:pfam17380  364 RIRQ---EEIAMEISRMRELERLQMERQQKNERVRqELEAARKVKILEEERQRKIQQQKVEMEQIRAEQE-----EARQR 435

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   670 ELESLKHQQdALWTEKLQVLKQQYQTEMEKLRE-KCEQEKETLLKDKEIIFQAHIEEMNEKTLEKldvkqtELESLSSEL 748
Cdd:pfam17380  436 EVRRLEEER-AREMERVRLEEQERQQQVERLRQqEEERKRKKLELEKEKRDRKRAEEQRRKILEK------ELEERKQAM 508

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   749 SEVLKARHKLEEElsvLKDQTDKMKQELEAKMDEQKNHHQQQVdsiikEHEVSIQRTEKALKDQINQLELLLKERD--KH 826
Cdd:pfam17380  509 IEEERKRKLLEKE---MEERQKAIYEEERRREAEEERRKQQEM-----EERRRIQEQMRKATEERSRLEAMEREREmmRQ 580

                          330
                   ....*....|...
gi 530372322   827 LKEHQAHVENLEA 839
Cdd:pfam17380  581 IVESEKARAEYEA 593
PTZ00121 PTZ00121
MAEBL; Provisional
 334-659 5.77e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 48.60  E-value: 5.77e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  334 KTLETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKnlIEQL 413
Cdd:PTZ00121 1535 KADEAKKAEEKKKADELKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMK--AEEA 1612

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  414 EQdkgmviAETKRQMHETLEMKEEE---IAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARrklKA 490
Cdd:PTZ00121 1613 KK------AEEAKIKAEELKKAEEEkkkVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAK---KA 1683

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  491 EMDEQIKTIEKTSEEERISLQQELSRVKQEVV---DVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMK 567
Cdd:PTZ00121 1684 EEDEKKAAEALKKEAEEAKKAEELKKKEAEEKkkaEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLK 1763

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  568 VALEKSQSEYLK-----ISQEKEQQESLALEELELQKKAILTESENkLRDLQQEAETYRTRILELESSLEKSLQENKNQS 642
Cdd:PTZ00121 1764 KEEEKKAEEIRKekeavIEEELDEEDEKRRMEVDKKIKDIFDNFAN-IIEGGKEGNLVINDSKEMEDSAIKEVADSKNMQ 1842

                         330
                  ....*....|....*..
gi 530372322  643 KDLAVHLEAEKNKHNKE 659
Cdd:PTZ00121 1843 LEEADAFEKHKFNKNNE 1859
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 337-1011 5.79e-05

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 48.43  E-value: 5.79e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   337 ETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLdeRLQELEKIKDLHMAEKTKLITQLRDAKNLIEQ---- 412
Cdd:TIGR00618  215 DTYHERKQVLEKELKHLREALQQTQQSHAYLTQKREAQEEQL--KKQQLLKQLRARIEELRAQEAVLEETQERINRarka 292

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   413 ----LEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKL 488
Cdd:TIGR00618  293 aplaAHIKAVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIRDAHEVATSIREISC 372

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   489 KAEMDEQ----IKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHekelARKEQELTKKLQTREREF-- 562
Cdd:TIGR00618  373 QQHTLTQhihtLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAH----AKKQQELQQRYAELCAAAit 448

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   563 -QEQMKVALEKSQSEYLKISQEKEQQESLALEELElQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQ 641
Cdd:TIGR00618  449 cTAQCEKLEKIHLQESAQSLKEREQQLQTKEQIHL-QETRKKAVVLARLLELQEEPCPLCGSCIHPNPARQDIDNPGPLT 527

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   642 SKDLAVHLEaeknkhnkeitvmVEKHKTELESLKHQQDALwTEKLQVLKQQYQTEMEKLREKCEQEKET-----LLKDKE 716
Cdd:TIGR00618  528 RRMQRGEQT-------------YAQLETSEEDVYHQLTSE-RKQRASLKEQMQEIQQSFSILTQCDNRSkedipNLQNIT 593

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   717 IIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQELEAKMDEQKnHHQQQVDSIIK 796
Cdd:TIGR00618  594 VRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQLTLTQERVR-EHALSIRVLPK 672

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   797 EHEVSIQRTEKAL----------KDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDvfQSYQSATH 866
Cdd:TIGR00618  673 ELLASRQLALQKMqsekeqltywKEMLAQCQTLLRELETHIEEYDREFNEIENASSSLGSDLAAREDALN--QSLKELMH 750

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   867 EQTKAYEEQLAQLQQKLLDLETERILLTkqvaeveaQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESK 946
Cdd:TIGR00618  751 QARTVLKARTEAHFNNNEEVTAALQTGA--------ELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQ 822

                          650       660       670       680       690       700
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 530372322   947 LEDGNKEQEQTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKM 1011
Cdd:TIGR00618  823 CETLVQEEEQFLSRLEEKSATLGEITHQLLKYEECSKQLAQLTQEQAKIIQLSDKLNGINQIKIQ 887
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 1300-1862 6.41e-05

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 48.30  E-value: 6.41e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1300 AILSRISHCQHRTTKVKEALLIKTCTVSELEAQLRQlteEQNTLNISFQQATHQLEEKENQ--------IKSMKADIE-- 1369
Cdd:pfam12128  273 LIASRQEERQETSAELNQLLRTLDDQWKEKRDELNG---ELSAADAAVAKDRSELEALEDQhgafldadIETAAADQEql 349

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1370 -SLVTEKEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEKE 1448
Cdd:pfam12128  350 pSWQSELENLEERLKALTGKHQDVTAKYNRRRSKIKEQNNRDIAGIKDKLAKIREARDRQLAVAEDDLQALESELREQLE 429

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1449 AAISSLRkqydEEKCELLDQVQDLSFKVD--TLSKEKISALEQVDDWSNKfsewkkkAQSRFTQHQNTVKELQIQLELKS 1526
Cdd:pfam12128  430 AGKLEFN----EEEYRLKSRLGELKLRLNqaTATPELLLQLENFDERIER-------AREEQEAANAEVERLQSELRQAR 498

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1527 KEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMELED-HITQKTIEI--ESLNEVL 1603
Cdd:pfam12128  499 KRRDQASEALRQASRRLEERQSALDELELQLFPQAGTLLHFLRKEAPDWEQSIGKVISPELlHRTDLDPEVwdGSVGGEL 578

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1604 KNYNQQKDIEHKELVQKLQHFQELGEEKD---NRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKAL 1680
Cdd:pfam12128  579 NLYGVKLDLKRIDVPEWAASEEELRERLDkaeEALQSAREKQAAAEEQLVQANGELEKASREETFARTALKNARLDLRRL 658

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1681 EDRLESESAAK---LAELKRKAEQKIAAIKKQlLSQMEEKEEQYKKGTESHLSELNTKLQEREREVhilEEKLKSVESSQ 1757
Cdd:pfam12128  659 FDEKQSEKDKKnkaLAERKDSANERLNSLEAQ-LKQLDKKHQAWLEEQKEQKREARTEKQAYWQVV---EGALDAQLALL 734

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1758 SETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQY----QERLI 1833
Cdd:pfam12128  735 KAAIAARRSGAKAELKALETWYKRDLASLGVDPDVIAKLKREIRTLERKIERIAVRRQEVLRYFDWYQETWlqrrPRLAT 814

                          570       580
                   ....*....|....*....|....*....
gi 530372322  1834 KLEHAEAKQHEDQSMIGHLQEELEEKNKK 1862
Cdd:pfam12128  815 QLSNIERAISELQQQLARLIADTKLRRAK 843
DUF3584 pfam12128
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ...
 613-1265 8.05e-05

Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.


Pssm-ID: 432349 [Multi-domain]  Cd Length: 1191  Bit Score: 48.30  E-value: 8.05e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   613 LQQEAETYRTRILEL-------------ESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQD 679
Cdd:pfam12128  246 LQQEFNTLESAELRLshlhfgyksdetlIASRQEERQETSAELNQLLRTLDDQWKEKRDELNGELSAADAAVAKDRSELE 325

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   680 ALWTEKLQVLKQQYQTEmeklreKCEQEKETLlkdkeiiFQAHIEEMNEKtLEKLDVKQteLESLSSELSEVLKARHKLE 759
Cdd:pfam12128  326 ALEDQHGAFLDADIETA------AADQEQLPS-------WQSELENLEER-LKALTGKH--QDVTAKYNRRRSKIKEQNN 389

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   760 EELSVLKDQTDKMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKA----------LKDQINQL----ELLLKERDK 825
Cdd:pfam12128  390 RDIAGIKDKLAKIREARDRQLAVAEDDLQALESELREQLEAGKLEFNEEeyrlksrlgeLKLRLNQAtatpELLLQLENF 469

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   826 -----HLKEHQ----AHVENLEADIKRSEG-------ELQQASAKLDVFQSYQSATHEQTKA---------YEEQLAQLQ 880
Cdd:pfam12128  470 derieRAREEQeaanAEVERLQSELRQARKrrdqaseALRQASRRLEERQSALDELELQLFPqagtllhflRKEAPDWEQ 549

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   881 QKLLDLETERILLTKQVAEV-EAQKKDVCT----ELDAHKIQVQDLMQqlekqnseMEQKVKSLTQVYESKLEDGNKEQE 955
Cdd:pfam12128  550 SIGKVISPELLHRTDLDPEVwDGSVGGELNlygvKLDLKRIDVPEWAA--------SEEELRERLDKAEEALQSAREKQA 621

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   956 QTKQILVEKENmilQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQ--ETLKKKLLDQE 1033
Cdd:pfam12128  622 AAEEQLVQANG---ELEKASREETFARTALKNARLDLRRLFDEKQSEKDKKNKALAERKDSANERLNslEAQLKQLDKKH 698

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1034 AKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELN--DVISIWEKKLNQQAE 1111
Cdd:pfam12128  699 QAWLEEQKEQKREARTEKQAYWQVVEGALDAQLALLKAAIAARRSGAKAELKALETWYKRDLAslGVDPDVIAKLKREIR 778

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1112 ELQEIHEiQLQEKEQEVAELKQkillfgCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNS-LAQDETKLKAh 1190
Cdd:pfam12128  779 TLERKIE-RIAVRRQEVLRYFD------WYQETWLQRRPRLATQLSNIERAISELQQQLARLIADTKLrRAKLEMERKA- 850

                          650       660       670       680       690       700       710
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 530372322  1191 LEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSeLTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLS 1265
Cdd:pfam12128  851 SEKQQVRLSENLRGLRCEMSKLATLKEDANSEQAQGS-IGERLAQLEDLKLKRDYLSESVKKYVEHFKNVIADHS 924
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
403-874 8.39e-05

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 48.11  E-value: 8.39e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  403 LRDAKNLIEQLEQDkgmvIAETK-RQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSE---------RAAFEELE 472
Cdd:PRK02224  182 LSDQRGSLDQLKAQ----IEEKEeKDLHERLNGLESELAELDEEIERYEEQREQARETRDEADevleeheerREELETLE 257

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  473 KALSTAQKTEEARRKLKAEMDEQIKTIEKTSEE-------------------ERISLQQE-LSRVKQEVVDVMkksseEQ 532
Cdd:PRK02224  258 AEIEDLRETIAETEREREELAEEVRDLRERLEEleeerddllaeaglddadaEAVEARREeLEDRDEELRDRL-----EE 332

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  533 IAKLQKLHEKElARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKK-----AILTESE 607
Cdd:PRK02224  333 CRVAAQAHNEE-AESLREDADDLEERAEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRERfgdapVDLGNAE 411

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  608 NKLRDLQQEAETYRTRILELESSLeKSLQENKNQSKDLavhLEA----------EKNKHNKEIT---VMVEKHKTELESL 674
Cdd:PRK02224  412 DFLEELREERDELREREAELEATL-RTARERVEEAEAL---LEAgkcpecgqpvEGSPHVETIEedrERVEELEAELEDL 487

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  675 KHQQDALwTEKLQVLKQQYQTE--MEKLREKCEQEKEtLLKDKEiifqAHIEEMNEKTLEKLDVKQTELESLSSELSEVL 752
Cdd:PRK02224  488 EEEVEEV-EERLERAEDLVEAEdrIERLEERREDLEE-LIAERR----ETIEEKRERAEELRERAAELEAEAEEKREAAA 561

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  753 KARHKLEEELSVLKdqtdkmkqELEAKMDEQKNHHQQ--QVDSIIKEHEVSIQRTEKaLKDQINQLELLLKERDKHLKEH 830
Cdd:PRK02224  562 EAEEEAEEAREEVA--------ELNSKLAELKERIESleRIRTLLAAIADAEDEIER-LREKREALAELNDERRERLAEK 632

                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....
gi 530372322  831 QAHVENLEADIkrSEGELQQASAKLDVFQSYQSATHEQTKAYEE 874
Cdd:PRK02224  633 RERKRELEAEF--DEARIEEAREDKERAEEYLEQVEEKLDELRE 674
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1973-2189 9.57e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 47.74  E-value: 9.57e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1973 LSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEhQQELEILKKEYDQEREEKIKQEQEDLELKHNST--LK 2050
Cdd:TIGR02168  269 LEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRER-LANLERQLEELEAQLEELESKLDELAEELAELEekLE 347

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  2051 QLMREFNtQLAQKEQELEMTIKETINKAQEVEAELLE------SHQEETNQLLKKIAEKDDDLKRTAKRYE----EILDA 2120
Cdd:TIGR02168  348 ELKEELE-SLEAELEELEAELEELESRLEELEEQLETlrskvaQLELQIASLNNEIERLEARLERLEDRRErlqqEIEEL 426

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 530372322  2121 REEEMTAKVRDLQTQLEELQKKYQQKLEQEENPgndNTQLAQKTTLISDSKLKEQEFREQIHNLEDRLK 2189
Cdd:TIGR02168  427 LKKLEEAELKELQAELEELEEELEELQEELERL---EEALEELREELEEAEQALDAAERELAQLQARLD 492
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 1983-2202 1.07e-04

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 47.74  E-value: 1.07e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1983 LEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEH---QQELEILKKEYDQereekIKQEQEDLELKhnstlKQLMREFNTQ 2059
Cdd:TIGR02168  244 LQEELKEAEEELEELTAELQELEEKLEELRLEVselEEEIEELQKELYA-----LANEISRLEQQ-----KQILRERLAN 313

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  2060 LAQKEQELEMTIKETINKAQEVEAELLEShQEETNQLLKKIAEKDDDLKRtakryeeiLDAREEEMTAKVRDLQTQLEEL 2139
Cdd:TIGR02168  314 LERQLEELEAQLEELESKLDELAEELAEL-EEKLEELKEELESLEAELEE--------LEAELEELESRLEELEEQLETL 384

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 530372322  2140 QKKYQQKLEQEEnpgNDNTQLAQKTTLISDSKLKEQEFREQIHNLEDRLKKYEKNVYATTVGT 2202
Cdd:TIGR02168  385 RSKVAQLELQIA---SLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEAELKELQAELEE 444
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 422-643 1.17e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 47.07  E-value: 1.17e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  422 AETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAfEELEKALSTAQKTEEARRKLKAEMDEQIKTIEK 501
Cdd:COG4942    19 ADAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQLAALERRI-AALARRIRALEQELAALEAELAELEKEIAELRA 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  502 TSEE------ERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLheKELARKEQELTKKLQTREREFQEQmKVALEKSQS 575
Cdd:COG4942    98 ELEAqkeelaELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYL--KYLAPARREQAEELRADLAELAAL-RAELEAERA 174

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 530372322  576 EyLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSK 643
Cdd:COG4942   175 E-LEALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAE 241
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 668-1750 1.22e-04

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 47.74  E-value: 1.22e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   668 KTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNeKTLEKLDVKQTELESLSSE 747
Cdd:TIGR01612  695 KAKLDDLKSKIDKEYDKIQNMETATVELHLSNIENKKNELLDIIVEIKKHIHGEINKDLN-KILEDFKNKEKELSNKIND 773

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   748 LSEVLKARHKLEEELSVLKDQTDKmKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHL 827
Cdd:TIGR01612  774 YAKEKDELNKYKSKISEIKNHYND-QINIDNIKDEDAKQNYDKSKEYIKTISIKEDEIFKIINEMKFMKDDFLNKVDKFI 852

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   828 KEHQAHVENLEADIK---------RSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILL-TKQV 897
Cdd:TIGR01612  853 NFENNCKEKIDSEHEqfaeltnkiKAEISDDKLNDYEKKFNDSKSLINEINKSIEEEYQNINTLKKVDEYIKICEnTKES 932

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   898 AEVEAQKKDVCTELDAHKIQVQDLMQQLEK------QNSEMEQKV---KSLTQVYESKLEDGNKEQEQTKQILVE----- 963
Cdd:TIGR01612  933 IEKFHNKQNILKEILNKNIDTIKESNLIEKsykdkfDNTLIDKINeldKAFKDASLNDYEAKNNELIKYFNDLKAnlgkn 1012

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   964 KENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEmqetlkkkLLDQEAKLKKELENT 1043
Cdd:TIGR01612 1013 KENMLYHQFDEKEKATNDIEQKIEDANKNIPNIEIAIHTSIYNIIDEIEKEIGKNIE--------LLNKEILEEAEINIT 1084

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1044 AL-ELSQKEKQFN----AKMLEMAQANSAG-ISDAVSRLETNQKEQIESLTEVHRRELNDVisiweKKLNQQAEELQEIH 1117
Cdd:TIGR01612 1085 NFnEIKEKLKHYNfddfGKEENIKYADEINkIKDDIKNLDQKIDHHIKALEEIKKKSENYI-----DEIKAQINDLEDVA 1159

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1118 EIQLQEKEQEVAELKQKILLFGCEK-----EEMNKEITWLKEEGvKQDTTLNELQEQLKQKSAHVNSL---AQDETKLKA 1189
Cdd:TIGR01612 1160 DKAISNDDPEEIEKKIENIVTKIDKkkniyDEIKKLLNEIAEIE-KDKTSLEEVKGINLSYGKNLGKLfleKIDEEKKKS 1238

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1190 H-----LEKLEVDLNKSLKentflQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKL 1264
Cdd:TIGR01612 1239 EhmikaMEAYIEDLDEIKE-----KSPEIENEMGIEMDIKAEMETFNISHDDDKDHHIISKKHDENISDIREKSLKIIED 1313

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1265 SEELAIQLDICCKKTEALLEAKTNelinisSSKTNAILSRISHCQHrttkvkealLIKTCTVSELEAQLRQLTEEQNTLN 1344
Cdd:TIGR01612 1314 FSEESDINDIKKELQKNLLDAQKH------NSDINLYLNEIANIYN---------ILKLNKIKKIIDEVKEYTKEIEENN 1378

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1345 isfQQATHQLEEKENQIKSMKADIeslvtekealqkeggNQQQAASEKESCITQlkKELSENINAVTLMKEELKEKKVEI 1424
Cdd:TIGR01612 1379 ---KNIKDELDKSEKLIKKIKDDI---------------NLEECKSKIESTLDD--KDIDECIKKIKELKNHILSEESNI 1438

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1425 SSLSKQLTDLNvqlqNSISLSEKEAAISSLRKQYDEeKCELLDQVQDLSFKVDTLsKEKISALEQVDDWSNKFSEWKKKA 1504
Cdd:TIGR01612 1439 DTYFKNADENN----ENVLLLFKNIEMADNKSQHIL-KIKKDNATNDHDFNINEL-KEHIDKSKGCKDEADKNAKAIEKN 1512

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1505 QSRFTQHQNTVKEL---QIQLELKSKEAYEKDEQINLLKEELDQQNKRFdcLKGEMEDDKSKMEKKEsnlETELKSQTAR 1581
Cdd:TIGR01612 1513 KELFEQYKKDVTELlnkYSALAIKNKFAKTKKDSEIIIKEIKDAHKKFI--LEAEKSEQKIKEIKKE---KFRIEDDAAK 1587

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1582 IMELEDHITQKTIEIESL-NEVLKNYNQQKDI-----EHKELVQKLQHFQElgEEKDNRVKEAEEKILTLENQVYSMKAE 1655
Cdd:TIGR01612 1588 NDKSNKAAIDIQLSLENFeNKFLKISDIKKKIndclkETESIEKKISSFSI--DSQDTELKENGDNLNSLQEFLESLKDQ 1665

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1656 ---LETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSEl 1732
Cdd:TIGR01612 1666 kknIEDKKKELDELDSEIEKIEIDVDQHKKNYEIGIIEKIKEIAIANKEEIESIKELIEPTIENLISSFNTNDLEGIDP- 1744

                         1130
                   ....*....|....*...
gi 530372322  1733 NTKLQEREREVHILEEKL 1750
Cdd:TIGR01612 1745 NEKLEEYNTEIGDIYEEF 1762
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
172-459 1.24e-04

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 47.60  E-value: 1.24e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  172 PSDMDSEAEDLVGNSDSLNK-EQLIQRLRRMERSLS---SYRGKYSELVTAYQMLQREKKKLQGILSQSQDKSLR-RIAE 246
Cdd:COG4913   220 EPDTFEAADALVEHFDDLERaHEALEDAREQIELLEpirELAERYAAARERLAELEYLRAALRLWFAQRRLELLEaELEE 299

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  247 LREELQMDQQAKKHLQEEFDASLEEKDQyisvlqtqvsLLKQRLRNGpmnVDVLKPLPQLEPQAEvftkeenpesdgepv 326
Cdd:COG4913   300 LRAELARLEAELERLEARLDALREELDE----------LEAQIRGNG---GDRLEQLEREIERLE--------------- 351

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  327 vedgtsvKTLETLQQRVKRQENLLKRCKETIQSHKEqctlltsEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDA 406
Cdd:COG4913   352 -------RELEERERRRARLEALLAALGLPLPASAE-------EFAALRAEAAALLEALEEELEALEEALAEAEAALRDL 417

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|...
gi 530372322  407 KNLIEQLEQdkgmviaetkrqmhetlemkeeEIAQLRSRIKQMTTQGEELREQ 459
Cdd:COG4913   418 RRELRELEA----------------------EIASLERRKSNIPARLLALRDA 448
rad50 TIGR00606
rad50; All proteins in this family for which functions are known are involvedin recombination, ...
 1009-1756 2.10e-04

rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).


Pssm-ID: 129694 [Multi-domain]  Cd Length: 1311  Bit Score: 46.96  E-value: 2.10e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1009 KKMEKVKQKAKEMQETL--KKKLLDQEAKLKKELENTALELSQKEKQfnakmLEMAQANSAGISDAVSRLETNQKEQies 1086
Cdd:TIGR00606  210 KYLKQYKEKACEIRDQItsKEAQLESSREIVKSYENELDPLKNRLKE-----IEHNLSKIMKLDNEIKALKSRKKQM--- 281

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1087 ltEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNEL 1166
Cdd:TIGR00606  282 --EKDNSELELKMEKVFQGTDEQLNDLYHNHQRTVREKERELVDCQRELEKLNKERRLLNQEKTELLVEQGRLQLQADRH 359

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1167 QEQLKQKSAHVNSLAqdetkLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSS 1246
Cdd:TIGR00606  360 QEHIRARDSLIQSLA-----TRLELDGFERGPFSERQIKNFHTLVIERQEDEAKTAAQLCADLQSKERLKQEQADEIRDE 434

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1247 HEKSNKSLEDKSLEFKKLSEELAI------QLDICCKKTEALLEAKTNELINISSSKTNAILSRISHCQHRTTKVKEALL 1320
Cdd:TIGR00606  435 KKGLGRTIELKKEILEKKQEELKFvikelqQLEGSSDRILELDQELRKAERELSKAEKNSLTETLKKEVKSLQNEKADLD 514

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1321 IKTCTVSELEAQLRQLTEEQNTLnisfQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLK 1400
Cdd:TIGR00606  515 RKLRKLDQEMEQLNHHTTTRTQM----EMLTKDKMDKDEQIRKIKSRHSDELTSLLGYFPNKKQLEDWLHSKSKEINQTR 590

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1401 KELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCEL-------------LD 1467
Cdd:TIGR00606  591 DRLAKLNKELASLEQNKNHINNELESKEEQLSSYEDKLFDVCGSQDEESDLERLKEEIEKSSKQRamlagatavysqfIT 670

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1468 QVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQN 1547
Cdd:TIGR00606  671 QLTDENQSCCPVCQRVFQTEAELQEFISDLQSKLRLAPDKLKSTESELKKKEKRRDEMLGLAPGRQSIIDLKEKEIPELR 750

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1548 KRFDCLKGEMEDDKSKMEKKESNLETELKSQTA----------------RIMELEDHITQKTIEIESLN-----EVLKNY 1606
Cdd:TIGR00606  751 NKLQKVNRDIQRLKNDIEEQETLLGTIMPEEESakvcltdvtimerfqmELKDVERKIAQQAAKLQGSDldrtvQQVNQE 830

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1607 NQQKDIEHKELVQKLQHFQELGEE----------KDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEE 1676
Cdd:TIGR00606  831 KQEKQHELDTVVSKIELNRKLIQDqqeqiqhlksKTNELKSEKLQIGTNLQRRQQFEEQLVELSTEVQSLIREIKDAKEQ 910

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1677 LKALEDRLE------SESAAKLAELKRKAEQKIAAIKKQ----------LLSQMEEKEEQYKKGTESHLSELNTKLQERE 1740
Cdd:TIGR00606  911 DSPLETFLEkdqqekEELISSKETSNKKAQDKVNDIKEKvknihgymkdIENKIQDGKDDYLKQKETELNTVNAQLEECE 990

                          810
                   ....*....|....*.
gi 530372322  1741 REVHILEEKLKSVESS 1756
Cdd:TIGR00606  991 KHQEKINEDMRLMRQD 1006
ClpA COG0542
ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein ...
 401-554 2.97e-04

ATP-dependent Clp protease, ATP-binding subunit ClpA [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440308 [Multi-domain]  Cd Length: 836  Bit Score: 46.23  E-value: 2.97e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  401 TQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMttqgeelrEQKEKSERAAFEELekalstaqk 480
Cdd:COG0542   411 EELDELERRLEQLEIEKEALKKEQDEASFERLAELRDELAELEEELEAL--------KARWEAEKELIEEI--------- 473

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  481 teearRKLKAEMDEQ---IKTIEKTSEEERISLQQELSRVKQEVvdvmkksSEEQIAK---------LQKLHEKE---LA 545
Cdd:COG0542   474 -----QELKEELEQRygkIPELEKELAELEEELAELAPLLREEV-------TEEDIAEvvsrwtgipVGKLLEGErekLL 541


                  ....*....
gi 530372322  546 RKEQELTKK 554
Cdd:COG0542   542 NLEEELHER 550
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
331-782 3.06e-04

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 46.19  E-value: 3.06e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  331 TSVKTLETLQQRVKRQENL---LKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLITQLRDAK 407
Cdd:PRK02224  231 QARETRDEADEVLEEHEERreeLETLEAEIEDLRETIAETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAE 310

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  408 NLIEQLE--QDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKekseraafEELEKALSTAQKTEEAR 485
Cdd:PRK02224  311 AVEARREelEDRDEELRDRLEECRVAAQAHNEEAESLREDADDLEERAEELREEA--------AELESELEEAREAVEDR 382

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  486 RKLKAEMDEQIKTIEKT----------SEEERISLQQELSRVKQEVVDVMK--KSSEEQIAKLQKLHEkelARKEQELTK 553
Cdd:PRK02224  383 REEIEELEEEIEELRERfgdapvdlgnAEDFLEELREERDELREREAELEAtlRTARERVEEAEALLE---AGKCPECGQ 459

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  554 KLQTRER-EFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTES-ENKLRDLQQEAETYRTRILELESSL 631
Cdd:PRK02224  460 PVEGSPHvETIEEDRERVEELEAELEDLEEEVEEVEERLERAEDLVEAEDRIERlEERREDLEELIAERRETIEEKRERA 539

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  632 EkSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKT---ELESLKHQQDALWT-EKLQVLKQQYQTEMEKLREKceqe 707
Cdd:PRK02224  540 E-ELRERAAELEAEAEEKREAAAEAEEEAEEAREEVAElnsKLAELKERIESLERiRTLLAAIADAEDEIERLREK---- 614

                         410       420       430       440       450       460       470
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 530372322  708 ketllkdkeiifQAHIEEMNEKTLEKLDVKQTELESLSSELSEV--LKARHKLEEELSVLKDQTDKMkQELEAKMDE 782
Cdd:PRK02224  615 ------------REALAELNDERRERLAEKRERKRELEAEFDEAriEEAREDKERAEEYLEQVEEKL-DELREERDD 678
PRK12704 PRK12704
phosphodiesterase; Provisional
 1101-1231 3.28e-04

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 45.92  E-value: 3.28e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1101 IWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGceKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSL 1180
Cdd:PRK12704   24 VRKKIAEAKIKEAEEEAKRILEEAKKEAEAIKKEALLEA--KEEIHKLRNEFEKELRERRNELQKLEKRLLQKEENLDRK 101

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 530372322 1181 AQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTS 1231
Cdd:PRK12704  102 LELLEKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQELERISGLTA 152
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1449-2076 3.48e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 45.88  E-value: 3.48e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1449 AAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQVddwsnkFSEWKKKAQSRFTQHQNTVKELQIQLELKSKE 1528
Cdd:pfam15921  220 SAISKILRELDTEISYLKGRIFPVEDQLEALKSESQNKIELL------LQQHQDRIEQLISEHEVEITGLTEKASSARSQ 293

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1529 AYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEkkeSNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQ 1608
Cdd:pfam15921  294 ANSIQSQLEIIQEQARNQNSMYMRQLSDLESTVSQLR---SELREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQ 370

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1609 qkdiEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESES 1688
Cdd:pfam15921  371 ----ESGNLDDQLQKLLADLHKREKELSLEKEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSECQGQM 446

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1689 AAKLAELKRKAE--QKIAAIKKQLLSQMEE-----KEEQYKKGT----ESHLSELNTKLQEREREVHILEEKLKSVESSQ 1757
Cdd:pfam15921  447 ERQMAAIQGKNEslEKVSSLTAQLESTKEMlrkvvEELTAKKMTlessERTVSDLTASLQEKERAIEATNAEITKLRSRV 526

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1758 SETLIVPRSAKNVAAYTEQEEADSQGcVQKTYEEKISVLQRNLTEKEKLLQRVGQ----------EKEETVSSHFEMRCQ 1827
Cdd:pfam15921  527 DLKLQELQHLKNEGDHLRNVQTECEA-LKLQMAEKDKVIEILRQQIENMTQLVGQhgrtagamqvEKAQLEKEINDRRLE 605

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1828 YQERLIKLEHAEAKQHEDQSMIGHLQEEleeknkKYSLIVAQHVEKEGGKNNIQAKQNL----ENVFDDVQKTLQEKELT 1903
Cdd:pfam15921  606 LQEFKILKDKKDAKIRELEARVSDLELE------KVKLVNAGSERLRAVKDIKQERDQLlnevKTSRNELNSLSEDYEVL 679

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1904 CQILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSHLvqpkllSNMEAQHNDL 1983
Cdd:pfam15921  680 KRNFRNKSEEMETTTNKLKMQLKSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQITAKRGQI------DALQSKIQFL 753

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1984 EFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQ---ELEILKKEydqerEEKIKQEQEDLELKHNSTLKQLMREFNTQL 2060
Cdd:pfam15921  754 EEAMTNANKEKHFLKEEKNKLSQELSTVATEKNKmagELEVLRSQ-----ERRLKEKVANMEVALDKASLQFAECQDIIQ 828

                          650
                   ....*....|....*.
gi 530372322  2061 AQKEQELEMTIKETIN 2076
Cdd:pfam15921  829 RQEQESVRLKLQHTLD 844
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 368-565 3.63e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 45.14  E-value: 3.63e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  368 TSEKEALQEQLDE---RLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDkgmvIAETKRQMHETlemkEEEIAQLRS 444
Cdd:COG4942    19 ADAAAEAEAELEQlqqEIAELEKELAALKKEEKALLKQLAALERRIAALARR----IRALEQELAAL----EAELAELEK 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  445 RIKQMTTQGEELREQKEKSERAA-----------------FEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEE-- 505
Cdd:COG4942    91 EIAELRAELEAQKEELAELLRALyrlgrqpplalllspedFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAEle 170

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 530372322  506 -----------ERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLheKELARKEQELTKKLQTREREFQEQ 565
Cdd:COG4942   171 aeraeleallaELEEERAALEALKAERQKLLARLEKELAELAAEL--AELQQEAEELEALIARLEAEAAAA 239
Macoilin pfam09726
Macoilin family; The Macoilin proteins has an N-terminal portion that is composed of 5 ...
 904-1135 4.48e-04

Macoilin family; The Macoilin proteins has an N-terminal portion that is composed of 5 trasnmembrane helices, followed by a C-terminal coiled-coil region. Macoilin is a highly conserved protein present in eukaryotes. Macoilin appears to be found in the ER and be involved in the function of neurons.


Pssm-ID: 462859 [Multi-domain]  Cd Length: 670  Bit Score: 45.61  E-value: 4.48e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   904 KKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYES-KLEDGNKEQEQtkQILVEKENMILQMREGQKKEIEIL 982
Cdd:pfam09726  393 KPDALVRLEQDIKKLKAELQASRQTEQELRSQISSLTSLERSlKSELGQLRQEN--DLLQTKLHNAVSAKQKDKQTVQQL 470

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   983 TQKLSAKEDSI----HILNEEYETKFKNQEKKMEKVKQKA---KEMQETLKKKLLDQEAKLKK-------------ELEN 1042
Cdd:pfam09726  471 EKRLKAEQEARasaeKQLAEEKKRKKEEEATAARAVALAAasrGECTESLKQRKRELESEIKKlthdiklkeeqirELEI 550

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1043 TALELSQKEKqfNAKMLEMAQANSAGISDAVSRLEtnqkeqiESLTEVHRRELnDVISiwekKLNQQAEELqEIHEIQLQ 1122
Cdd:pfam09726  551 KVQELRKYKE--SEKDTEVLMSALSAMQDKNQHLE-------NSLSAETRIKL-DLFS----ALGDAKRQL-EIAQGQIY 615

                          250
                   ....*....|...
gi 530372322  1123 EKEQEVAELKQKI 1135
Cdd:pfam09726  616 QKDQEIKDLKQKI 628
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
409-569 5.02e-04

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 45.23  E-value: 5.02e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  409 LIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQ-KEKSERAafEELEKALSTAQKteEARRK 487
Cdd:COG2433   385 LIEKELPEEEPEAEREKEHEERELTEEEEEIRRLEEQVERLEAEVEELEAElEEKDERI--ERLERELSEARS--EERRE 460

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  488 LKaemdeqiKTIEKTSEEERIS-LQQELSRVKQEVvdvmkKSSEEQIAKLQKLHEKElARKEQELTKKLQ--TRE--REF 562
Cdd:COG2433   461 IR-------KDREISRLDREIErLERELEEERERI-----EELKRKLERLKELWKLE-HSGELVPVKVVEkfTKEaiRRL 527


                  ....*..
gi 530372322  563 QEQMKVA 569
Cdd:COG2433   528 EEEYGLK 534
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 753-941 5.22e-04

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 44.75  E-value: 5.22e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  753 KARHKLEEELSVLKDQTDKMKQELEAKMDEQKNHHQQqvdsiIKEHEVSIQRTEKALKD---QINQLELLLKERDKHLKE 829
Cdd:COG4942    20 DAAAEAEAELEQLQQEIAELEKELAALKKEEKALLKQ-----LAALERRIAALARRIRAleqELAALEAELAELEKEIAE 94

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  830 HQAHVENLEADIKR------------------SEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERI 891
Cdd:COG4942    95 LRAELEAQKEELAEllralyrlgrqpplalllSPEDFLDAVRRLQYLKYLAPARREQAEELRADLAELAALRAELEAERA 174

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 530372322  892 LLTKQVAEVEAQKKdvctELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQ 941
Cdd:COG4942   175 ELEALLAELEEERA----ALEALKAERQKLLARLEKELAELAAELAELQQ 220
COG2433 COG2433
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
1597-1749 6.37e-04

Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];


Pssm-ID: 441980 [Multi-domain]  Cd Length: 644  Bit Score: 44.85  E-value: 6.37e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1597 ESLNEVLKnynqqkDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVysmkAELETKKKELEHvnlSVKSKEEE 1676
Cdd:COG2433   376 LSIEEALE------ELIEKELPEEEPEAEREKEHEERELTEEEEEIRRLEEQV----ERLEAEVEELEA---ELEEKDER 442

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 530372322 1677 LKALEDRLESESAAKLAELKRKAE-QKIAAIKKQLLSQMEEKEEqykkgtesHLSELNTKLqEREREVHILEEK 1749
Cdd:COG2433   443 IERLERELSEARSEERREIRKDREiSRLDREIERLERELEEERE--------RIEELKRKL-ERLKELWKLEHS 507
46 PHA02562
endonuclease subunit; Provisional
 1165-1408 7.66e-04

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 44.62  E-value: 7.66e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1165 ELQEQLKQKSAHVNSLaqdETKLKAHlEKLEVDLNKSLKEN-TFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSL 1243
Cdd:PHA02562  178 ELNQQIQTLDMKIDHI---QQQIKTY-NKNIEEQRKKNGENiARKQNKYDELVEEAKTIKAEIEELTDELLNLVMDIEDP 253

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1244 KSSHEKSNKSLEDKSLEFKKLSEELAIQLD--ICCKKTEALLEakTNELINisssktnAILSRISHCQHRTTKVKEAlli 1321
Cdd:PHA02562  254 SAALNKLNTAAAKIKSKIEQFQKVIKMYEKggVCPTCTQQISE--GPDRIT-------KIKDKLKELQHSLEKLDTA--- 321

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1322 ktctVSELEAQLRQLTEEQNTLNisfqqathqleEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLKK 1401
Cdd:PHA02562  322 ----IDELEEIMDEFNEQSKKLL-----------ELKNKISTNKQSLITLVDKAKKVKAAIEELQAEFVDNAEELAKLQD 386


                  ....*..
gi 530372322 1402 ELSENIN 1408
Cdd:PHA02562  387 ELDKIVK 393
SMC_N pfam02463
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ...
 1186-2044 8.01e-04

RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.


Pssm-ID: 426784 [Multi-domain]  Cd Length: 1161  Bit Score: 44.96  E-value: 8.01e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1186 KLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEfKKLS 1265
Cdd:pfam02463  170 KKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLNEERIDLLQE-LLRD 248

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1266 EELAIQLDICCKKTEALLEAKTNELINISSSKTNAILSRISHCQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNI 1345
Cdd:pfam02463  249 EQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLERRKVDDEEKLKESEKEKKKAEK 328

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1346 SFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEKKVEIS 1425
Cdd:pfam02463  329 ELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKEAQ 408

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1426 S---LSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDwSNKFSEWKK 1502
Cdd:pfam02463  409 LlleLARQLEDLLKEEKKEELEILEEEEESIELKQGKLTEEKEELEKQELKLLKDELELKKSEDLLKETQ-LVKLQEQLE 487

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1503 KAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTA-- 1580
Cdd:pfam02463  488 LLLSRQKLEERSQKESKARSGLKVLLALIKDGVGGRIISAHGRLGDLGVAVENYKVAISTAVIVEVSATADEVEERQKlv 567

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1581 RIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAE------EKILTLENQVYSMKA 1654
Cdd:pfam02463  568 RALTELPLGARKLRLLIPKLKLPLKSIAVLEIDPILNLAQLDKATLEADEDDKRAKVVEgilkdtELTKLKESAKAKESG 647

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1655 ELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNT 1734
Cdd:pfam02463  648 LRKGVSLEEGLAEKSEVKASLSELTKELLEIQELQEKAESELAKEEILRRQLEIKKKEQREKEELKKLKLEAEELLADRV 727

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1735 KLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKisvlQRNLTEKEKLLQRVGQEK 1814
Cdd:pfam02463  728 QEAQDKINEELKLLKQKIDEEEEEEEKSRLKKEEKEEEKSELSLKEKELAEEREKTEK----LKVEEEKEEKLKAQEEEL 803

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1815 EETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMigHLQEELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENVFDDVQ 1894
Cdd:pfam02463  804 RALEEELKEEAELLEEEQLLIEQEEKIKEEELEE--LALELKEEQKLEKLAEEELERLEEEITKEELLQELLLKEEELEE 881

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1895 KTLQEKELTCQILEQKIKELDSCLVRQKEVHRVEMEELTSKYEKLQALQQMDGRnkptelleenteEKSKSHLVQPKLLS 1974
Cdd:pfam02463  882 QKLKDELESKEEKEKEEKKELEEESQKLNLLEEKENEIEERIKEEAEILLKYEE------------EPEELLLEEADEKE 949

                          810       820       830       840       850       860       870
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1975 NMEAQHNDLEFKLAGAEREKQKLGKEIVRLqkDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELK 2044
Cdd:pfam02463  950 KEENNKEEEEERNKRLLLAKEELGKVNLMA--IEEFEEKEERYNKDELEKERLEEEKKKLIRAIIEETCQ 1017
PRK03918 PRK03918
DNA double-strand break repair ATPase Rad50;
1163-1754 8.16e-04

DNA double-strand break repair ATPase Rad50;


Pssm-ID: 235175 [Multi-domain]  Cd Length: 880  Bit Score: 44.67  E-value: 8.16e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1163 LNELQEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELkmlaEEDKRKVSELTSKLKTTDEEFQS 1242
Cdd:PRK03918  167 LGEVIKEIKRRIERLEKFIKRTENIEELIKEKEKELEEVLREINEISSELPEL----REELEKLEKEVKELEELKEEIEE 242

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1243 LK---SSHEKSNKSLEDKSLEFKKLSEELaiqldiccKKTEALLEAKTNELINISSSKTNAIlsRISHCQHRTTKVKEAL 1319
Cdd:PRK03918  243 LEkelESLEGSKRKLEEKIRELEERIEEL--------KKEIEELEEKVKELKELKEKAEEYI--KLSEFYEEYLDELREI 312

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1320 LIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLvteKEALQKEGGNQQQAASEKESCITQL 1399
Cdd:PRK03918  313 EKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELY---EEAKAKKEELERLKKRLTGLTPEKL 389

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1400 KKELSENINAVTLMKEELKEKKVEISSLSKQLTDLNvqlQNSISLSEKEAAISSLRKQYDEEkcELLDQVQDLSFKVDTL 1479
Cdd:PRK03918  390 EKELEELEKAKEEIEEEISKITARIGELKKEIKELK---KAIEELKKAKGKCPVCGRELTEE--HRKELLEEYTAELKRI 464

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1480 SKEKISALEQVDDWSNKFSEWKK--KAQSRFTQHQNTVKELqiqlelksKEAYEKDEQINLlkEELDQQNKRFDCLKGEM 1557
Cdd:PRK03918  465 EKELKEIEEKERKLRKELRELEKvlKKESELIKLKELAEQL--------KELEEKLKKYNL--EELEKKAEEYEKLKEKL 534

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1558 eddkSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKdNRVKE 1637
Cdd:PRK03918  535 ----IKLKGEIKSLKKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNEY-LELKD 609

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1638 AEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQlLSQMEEK 1717
Cdd:PRK03918  610 AEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEELREEYLELSRELAGLRAE-LEELEKR 688

                         570       580       590
                  ....*....|....*....|....*....|....*..
gi 530372322 1718 EEQYKKGTEShLSELNTKLQEREREVHILEEKLKSVE 1754
Cdd:PRK03918  689 REEIKKTLEK-LKEELEEREKAKKELEKLEKALERVE 724
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1526-1759 1.01e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 43.98  E-value: 1.01e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1526 SKEAYEKDEQINLLKEELDQQNKRFDCLKGE---MEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLnev 1602
Cdd:COG4942    19 ADAAAEAEAELEQLQQEIAELEKELAALKKEekaLLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAEL--- 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1603 lknyNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEhvnlSVKSKEEELKALED 1682
Cdd:COG4942    96 ----RAELEAQKEELAELLRALYRLGRQPPLALLLSPEDFLDAVRRLQYLKYLAPARREQAE----ELRADLAELAALRA 167

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 530372322 1683 RLESESAAKLAELKRKAEQkiaaiKKQLLSQMEEKEEQYKKgTESHLSELNTKLQEREREVHILEEKLKSVESSQSE 1759
Cdd:COG4942   168 ELEAERAELEALLAELEEE-----RAALEALKAERQKLLAR-LEKELAELAAELAELQQEAEELEALIARLEAEAAA 238
PRK01156 PRK01156
chromosome segregation protein; Provisional
 809-1405 1.12e-03

chromosome segregation protein; Provisional


Pssm-ID: 100796 [Multi-domain]  Cd Length: 895  Bit Score: 44.12  E-value: 1.12e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  809 LKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQ---SATHEQTKAYEEQLAQLQQKLLD 885
Cdd:PRK01156  188 LEEKLKSSNLELENIKKQIADDEKSHSITLKEIERLSIEYNNAMDDYNNLKSALnelSSLEDMKNRYESEIKTAESDLSM 267

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  886 LETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQnSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKE 965
Cdd:PRK01156  268 ELEKNNYYKELEERHMKIINDPVYKNRNYINDYFKYKNDIENK-KQILSNIDAEINKYHAIIKKLSVLQKDYNDYIKKKS 346

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  966 nmilqmregQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEA--KLKKELENT 1043
Cdd:PRK01156  347 ---------RYDDLNNQILELEGYEMDYNSYLKSIESLKKKIEEYSKNIERMSAFISEILKIQEIDPDAikKELNEINVK 417

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1044 ALELSQKEKQFNAKMLEMAQaNSAGISDAVSRLETNQKEQIESlTEVHRRELNDVISIWEKKLNQQAEELQEIhEIQLQE 1123
Cdd:PRK01156  418 LQDISSKVSSLNQRIRALRE-NLDELSRNMEMLNGQSVCPVCG-TTLGEEKSNHIINHYNEKKSRLEEKIREI-EIEVKD 494

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1124 KEQEVAELKQkiLLFGCEKEEMNKEITwlkeegvkQDTTLNELQEQLKQKSAHVNSLAQDETKLKA--------HLEKLE 1195
Cdd:PRK01156  495 IDEKIVDLKK--RKEYLESEEINKSIN--------EYNKIESARADLEDIKIKINELKDKHDKYEEiknrykslKLEDLD 564

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1196 VDLNKSLKENTFLQEQLVE-LKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEF---KKLSEELAIQ 1271
Cdd:PRK01156  565 SKRTSWLNALAVISLIDIEtNRSRSNEIKKQLNDLESRLQEIEIGFPDDKSYIDKSIREIENEANNLnnkYNEIQENKIL 644

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1272 LDICCKKTEALLEaKTNELINISSSKtNAILSRISHCQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQAT 1351
Cdd:PRK01156  645 IEKLRGKIDNYKK-QIAEIDSIIPDL-KEITSRINDIEDNLKKSRKALDDAKANRARLESTIEILRTRINELSDRINDIN 722

                         570       580       590       600       610
                  ....*....|....*....|....*....|....*....|....*....|....
gi 530372322 1352 HQLEEKenqiKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLKKELSE 1405
Cdd:PRK01156  723 ETLESM----KKIKKAIGDLKRLREAFDKSGVPAMIRKSASQAMTSLTRKYLFE 772
235kDa-fam TIGR01612
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ...
 334-1777 1.42e-03

reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.


Pssm-ID: 130673 [Multi-domain]  Cd Length: 2757  Bit Score: 44.27  E-value: 1.42e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   334 KTLETLQQRVKRQENLLKRCKETIQSHKE--QCTLLTSEKEALQEQLDERLQELEKIKDLHmAEKTKLITQLRDAKNLIE 411
Cdd:TIGR01612 1129 HHIKALEEIKKKSENYIDEIKAQINDLEDvaDKAISNDDPEEIEKKIENIVTKIDKKKNIY-DEIKKLLNEIAEIEKDKT 1207

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   412 QLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFE-------------------ELE 472
Cdd:TIGR01612 1208 SLEEVKGINLSYGKNLGKLFLEKIDEEKKKSEHMIKAMEAYIEDLDEIKEKSPEIENEmgiemdikaemetfnishdDDK 1287

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   473 KALSTAQKTEEARRKLKaemDEQIKTIEKTSEEERI-----SLQQELSRVKQEVVDVMKKSSE----EQIAKLQKLheKE 543
Cdd:TIGR01612 1288 DHHIISKKHDENISDIR---EKSLKIIEDFSEESDIndikkELQKNLLDAQKHNSDINLYLNEianiYNILKLNKI--KK 1362

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   544 LARKEQELTKKLQtrerEFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAIltesenklRDLQQEAETYRTR 623
Cdd:TIGR01612 1363 IIDEVKEYTKEIE----ENNKNIKDELDKSEKLIKKIKDDINLEECKSKIESTLDDKDI--------DECIKKIKELKNH 1430

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   624 ILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEK-------HKTELESLKHQQD------------ALWTE 684
Cdd:TIGR01612 1431 ILSEESNIDTYFKNADENNENVLLLFKNIEMADNKSQHILKIKkdnatndHDFNINELKEHIDkskgckdeadknAKAIE 1510

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   685 KLQVLKQQYQTEMEKLREK-----CEQEKETLLKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLE 759
Cdd:TIGR01612 1511 KNKELFEQYKKDVTELLNKysalaIKNKFAKTKKDSEIIIKEIKDAHKKFILEAEKSEQKIKEIKKEKFRIEDDAAKNDK 1590

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   760 EELSVLKDQTDkmKQELEAKMDEQKNhHQQQVDSIIKEHEvSIQRTEKALkdQINQLELLLKERDKHLKEHQAHVENLEA 839
Cdd:TIGR01612 1591 SNKAAIDIQLS--LENFENKFLKISD-IKKKINDCLKETE-SIEKKISSF--SIDSQDTELKENGDNLNSLQEFLESLKD 1664

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   840 DIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVaeVEAQKKDVCTELDAHKIQVQ 919
Cdd:TIGR01612 1665 QKKNIEDKKKELDELDSEIEKIEIDVDQHKKNYEIGIIEKIKEIAIANKEEIESIKEL--IEPTIENLISSFNTNDLEGI 1742

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   920 DLMQQLEKQNSEMEQKVKSLTQVYE---SKLEDGNKEQ---EQTKQILVEKENMILQMREGQKK-----------EIEIL 982
Cdd:TIGR01612 1743 DPNEKLEEYNTEIGDIYEEFIELYNiiaGCLETVSKEPityDEIKNTRINAQNEFLKIIEIEKKsksylddieakEFDRI 1822

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   983 TQKLSAKEDSIHI-LNEEYET---KFKNQEKKMEKVKQKAKE---------MQETLKKKLLDQEAKLKKELENTALELSQ 1049
Cdd:TIGR01612 1823 INHFKKKLDHVNDkFTKEYSKineGFDDISKSIENVKNSTDEnllfdilnkTKDAYAGIIGKKYYSYKDEAEKIFINISK 1902

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1050 KEKQFNAKMlemaqANSAGIS-------DAVSRLETNQKEQI----------ESLTEVhRRELNDVISIWEKKLNQQAEE 1112
Cdd:TIGR01612 1903 LANSINIQI-----QNNSGIDlfdniniAILSSLDSEKEDTLkfipspekepEIYTKI-RDSYDTLLDIFKKSQDLHKKE 1976

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1113 LQEIHEI----QLQEKEQEVAELKQKILLFGCEKEEMNKEITWLkeegVKQDTTLNELQEQLKQKSAHVNSLAQDETKLK 1188
Cdd:TIGR01612 1977 QDTLNIIfenqQLYEKIQASNELKDTLSDLKYKKEKILNDVKLL----LHKFDELNKLSCDSQNYDTILELSKQDKIKEK 2052

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1189 A-----HLEKLEVDLNKSLKENTFLQ-----EQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKS 1258
Cdd:TIGR01612 2053 IdnyekEKEKFGIDFDVKAMEEKFDNdikdiEKFENNYKHSEKDNHDFSEEKDNIIQSKKKLKELTEAFNTEIKIIEDKI 2132

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1259 LEFKKLSEELAIQLDICCKKTEA-LLEAKTNELINISSSKTNAilsrishcqhrttkvkeallikTCTVSELEAQLRQLT 1337
Cdd:TIGR01612 2133 IEKNDLIDKLIEMRKECLLFSYAtLVETLKSKVINHSEFITSA----------------------AKFSKDFFEFIEDIS 2190

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1338 EEQNTlNISFQQATHQLEEKENQIKSMKADIESlvTEKEALQKEggnqqQAASEKESCITQLKKELSENINAVTLMKEEL 1417
Cdd:TIGR01612 2191 DSLND-DIDALQIKYNLNQTKKHMISILADATK--DHNNLIEKE-----KEATKIINNLTELFTIDFNNADADILHNNKI 2262

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1418 kekkveisslskQLTDLNVQLQNSislsekeaaISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEkisaleqvddwsnkF 1497
Cdd:TIGR01612 2263 ------------QIIYFNSELHKS---------IESIKKLYKKINAFKLLNISHINEKYFDISKE--------------F 2307

                         1290      1300      1310      1320      1330      1340      1350      1360
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1498 SEWKKKAQSRFTQHQNTVKELqiqlelkskEAYEKDEQINLLKEELDQQNKRFDCLKgEMEDDKSKMEKKESNLETELKS 1577
Cdd:TIGR01612 2308 DNIIQLQKHKLTENLNDLKEI---------DQYISDKKNIFLHALNENTNFNFNALK-EIYDDIINRENKADEIENINNK 2377

                         1370      1380      1390      1400      1410      1420      1430      1440
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1578 QTARIMELEDHITQKTIEIESL----------NEVLKNYNQQKDIEH-----KELVQKLQHFQELgeekDNRVKEAEEKI 1642
Cdd:TIGR01612 2378 ENENIMQYIDTITKLTEKIQDIlifvttyendNNIIKQHIQDNDENDvskikDNLKKTIQSFQEI----LNKIDEIKAQF 2453

                         1450      1460      1470      1480      1490      1500      1510      1520
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1643 LTlENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYK 1722
Cdd:TIGR01612 2454 YG-GNNINNIIITISQNANDVKNHFSKDLTIENELIQIQKRLEDIKNAAHEIRSEQITKYTNAIHNHIEEQFKKIENNSN 2532

                         1530      1540      1550      1560      1570
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 530372322  1723 KGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQE 1777
Cdd:TIGR01612 2533 KDEVYKINEIDNIIEKIINYNKEPEVKLHAIIDNKNEFASIIPDIKNLIALIESE 2587
DR0291 COG1579
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ...
 1542-1713 1.72e-03

Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];


Pssm-ID: 441187 [Multi-domain]  Cd Length: 236  Bit Score: 42.22  E-value: 1.72e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1542 ELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDiehkeLVQKL 1621
Cdd:COG1579    14 ELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELEDLEKEIKRLELEIEEVEARIKKYEEQLG-----NVRNN 88

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1622 QHFQELGEEKDNrvkeAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESA---AKLAELKRK 1698
Cdd:COG1579    89 KEYEALQKEIES----LKRRISDLEDEILELMERIEELEEELAELEAELAELEAELEEKKAELDEELAeleAELEELEAE 164

                         170
                  ....*....|....*
gi 530372322 1699 AEQKIAAIKKQLLSQ 1713
Cdd:COG1579   165 REELAAKIPPELLAL 179
MukB COG3096
Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell ...
 192-443 1.73e-03

Chromosome condensin MukBEF, ATPase and DNA-binding subunit MukB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 442330 [Multi-domain]  Cd Length: 1470  Bit Score: 43.79  E-value: 1.73e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  192 EQLIQRLRRMERSLSSYRGKYSELVTAYQMLQREKKKLQGILSQS---QDKSL-RRIAELREELQMDQQAKKHLQeEFDA 267
Cdd:COG3096   839 AALRQRRSELERELAQHRAQEQQLRQQLDQLKEQLQLLNKLLPQAnllADETLaDRLEELREELDAAQEAQAFIQ-QHGK 917

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  268 SLEEKDQYISVLQT---QVSLLKQRLRNGPMNVDVLKplPQLEPQAEVFTKEENPESDGEPVVEDGTSVKTlETLQQRVK 344
Cdd:COG3096   918 ALAQLEPLVAVLQSdpeQFEQLQADYLQAKEQQRRLK--QQIFALSEVVQRRPHFSYEDAVGLLGENSDLN-EKLRARLE 994

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  345 RQENLLKRCKETIQSHKEQC-------TLLTSEKEALQEQLDERLQELEKIK---DLHMAEKTK-----LITQLRDAKNL 409
Cdd:COG3096   995 QAEEARREAREQLRQAQAQYsqynqvlASLKSSRDAKQQTLQELEQELEELGvqaDAEAEERARirrdeLHEELSQNRSR 1074

                         250       260       270
                  ....*....|....*....|....*....|....
gi 530372322  410 IEQLEQDKGMVIAETKrQMHETLEMKEEEIAQLR 443
Cdd:COG3096  1075 RSQLEKQLTRCEAEMD-SLQKRLRKAERDYKQER 1107
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
819-1243 1.75e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 43.60  E-value: 1.75e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  819 LLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERIL-----L 893
Cdd:COG4717    51 LEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLlqllpL 130

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  894 TKQVAEVEAQKKDVCTELDAHKIQVQDLmQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTKQILVEKENMILQMRE 973
Cdd:COG4717   131 YQELEALEAELAELPERLEELEERLEEL-RELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLA 209

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  974 GQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKA-------KEMQETLKKKLLDQEAKLKKELENTALE 1046
Cdd:COG4717   210 ELEEELEEAQEELEELEEELEQLENELEAAALEERLKEARLLLLIaaallalLGLGGSLLSLILTIAGVLFLVLGLLALL 289

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1047 LSQKEKQFNAKMLEMAQANSAGISDAVSRLE-TNQKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKE 1125
Cdd:COG4717   290 FLLLAREKASLGKEAEELQALPALEELEEEElEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELE 369

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1126 QEVAELKQKillFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQ--KSAHVNSLAQDETKLKAHLEKLEVDLNKSLK 1203
Cdd:COG4717   370 QEIAALLAE---AGVEDEEELRAALEQAEEYQELKEELEELEEQLEEllGELEELLEALDEEELEEELEELEEELEELEE 446

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|..
gi 530372322 1204 ENTFLQEQLVELK--MLAEEDKRKVSELTSKLKTTDEEFQSL 1243
Cdd:COG4717   447 ELEELREELAELEaeLEQLEEDGELAELLQELEELKAELREL 488
PRK12704 PRK12704
phosphodiesterase; Provisional
 369-506 1.88e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 43.23  E-value: 1.88e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  369 SEKEALQEQLDERLQELEKIKDLhmaeKTKLITQLRDAKNLIEQLEQdKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQ 448
Cdd:PRK12704   47 AKKEAEAIKKEALLEAKEEIHKL----RNEFEKELRERRNELQKLEK-RLLQKEENLDRKLELLEKREEELEKKEKELEQ 121

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 530372322  449 MTTQGEELREQKEKSERAAFEELEK--ALSTAQKT----EEARRKLKAEMDEQIKTIEKTSEEE 506
Cdd:PRK12704  122 KQQELEKKEEELEELIEEQLQELERisGLTAEEAKeillEKVEEEARHEAAVLIKEIEEEAKEE 185
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1973-2149 1.96e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.83  E-value: 1.96e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1973 LSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQELEILKKE----YDQEREEKIK----QEQEDLELK 2044
Cdd:COG4942    57 LAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELlralYRLGRQPPLAlllsPEDFLDAVR 136

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 2045 HNSTLKQLMREFNTQLAQKEQELEM--TIKETINKAQEVEAELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEiLDARE 2122
Cdd:COG4942   137 RLQYLKYLAPARREQAEELRADLAElaALRAELEAERAELEALLAELEEERAALEALKAERQKLLARLEKELAE-LAAEL 215

                         170       180
                  ....*....|....*....|....*..
gi 530372322 2123 EEMTAKVRDLQTQLEELQKKYQQKLEQ 2149
Cdd:COG4942   216 AELQQEAEELEALIARLEAEAAAAAER 242
SCP-1 pfam05483
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ...
 1104-1698 2.28e-03

Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.


Pssm-ID: 114219 [Multi-domain]  Cd Length: 787  Bit Score: 43.17  E-value: 2.28e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1104 KKLNQQAEELQEIHEIQLQEKEQEVAELkqkiLLFGCEKEEMNKEITWLKEEGVKQdttLNELQEQLKQKSAHVNSLAQD 1183
Cdd:pfam05483  218 KEDHEKIQHLEEEYKKEINDKEKQVSLL----LIQITEKENKMKDLTFLLEESRDK---ANQLEEKTKLQDENLKELIEK 290

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1184 ETKLKAHLEKLEVDLNKSLKENTFLQEQLvelkmlaEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKK 1263
Cdd:pfam05483  291 KDHLTKELEDIKMSLQRSMSTQKALEEDL-------QIATKTICQLTEEKEAQMEELNKAKAAHSFVVTEFEATTCSLEE 363

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1264 LSEELAIQLDicckKTEALLEAKTNELinisssktnailsrishcQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTL 1343
Cdd:pfam05483  364 LLRTEQQRLE----KNEDQLKIITMEL------------------QKKSSELEEMTKFKNNKEVELEELKKILAEDEKLL 421

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1344 --NISFQQATHQLEEKENQIKSMKADIESLVTEKEA-LQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEELKEK 1420
Cdd:pfam05483  422 deKKQFEKIAEELKGKEQELIFLLQAREKEIHDLEIqLTAIKTSEEHYLKEVEDLKTELEKEKLKNIELTAHCDKLLLEN 501

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1421 KVEISSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEW 1500
Cdd:pfam05483  502 KELTQEASDMTLELKKHQEDIINCKKQEERMLKQIENLEEKEMNLRDELESVREEFIQKGDEVKCKLDKSEENARSIEYE 581

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1501 KKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDC-------LKGEMEDDKSKMEKKESNLET 1573
Cdd:pfam05483  582 VLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKKKGSAENKQLNAyeikvnkLELELASAKQKFEEIIDNYQK 661

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1574 ELKSQTARIMELEDHITQKTIEIESLNEVLKNYN---QQKDIEHKELVQKLQH-FQELGEEKDNRVKEAEEKiltlENQV 1649
Cdd:pfam05483  662 EIEDKKISEEKLLEEVEKAKAIADEAVKLQKEIDkrcQHKIAEMVALMEKHKHqYDKIIEERDSELGLYKNK----EQEQ 737

                          570       580       590       600
                   ....*....|....*....|....*....|....*....|....*....
gi 530372322  1650 YSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRK 1698
Cdd:pfam05483  738 SSAKAALEIELSNIKAELLSLKKQLEIEKEEKEKLKMEAKENTAILKDK 786
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 334-537 2.70e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 42.44  E-value: 2.70e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  334 KTLETLQQRVKRQENLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERLQELEKIKD----LHMAEKTKLITQLRDAKNL 409
Cdd:COG4942    55 KQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEELAELLRalyrLGRQPPLALLLSPEDFLDA 134

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  410 IEQLEQDKGmvIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERaafeELEKALSTAQKTEEARRKLK 489
Cdd:COG4942   135 VRRLQYLKY--LAPARREQAEELRADLAELAALRAELEAERAELEALLAELEEERA----ALEALKAERQKLLARLEKEL 208

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 530372322  490 AEMDEQIKTIEKtseeERISLQQELSRVKQEVVDVMKKSSEEQIAKLQ 537
Cdd:COG4942   209 AELAAELAELQQ----EAEELEALIARLEAEAAAAAERTPAAGFAALK 252
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 195-587 2.89e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 43.18  E-value: 2.89e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   195 IQRLRRMERSLSSY-RGKYSELVTAYQMLQREKKKLQGILSQ--SQDKSLRRIAELREELQMDQQAKKHLQEEFDASLEE 271
Cdd:pfam15921  428 VQRLEALLKAMKSEcQGQMERQMAAIQGKNESLEKVSSLTAQleSTKEMLRKVVEELTAKKMTLESSERTVSDLTASLQE 507

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   272 KDQYISVLQTQVSLLKQRlrngpmnVDV-LKPLPQLEPQAEVFtkeENPESDGEPV-VEDGTSVKTLETLQQRVKRQENL 349
Cdd:pfam15921  508 KERAIEATNAEITKLRSR-------VDLkLQELQHLKNEGDHL---RNVQTECEALkLQMAEKDKVIEILRQQIENMTQL 577

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   350 L---KRCKETIQSHKEQCT-------LLTSEKEALQEQLDERLQELE-KIKDLHMaEKTKLITQLRDAKNLIEQLEQDKG 418
Cdd:pfam15921  578 VgqhGRTAGAMQVEKAQLEkeindrrLELQEFKILKDKKDAKIRELEaRVSDLEL-EKVKLVNAGSERLRAVKDIKQERD 656

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   419 MVIAETKRQMHETLEMKEE-EIAQ--LRSRIKQMTTQGEELREQKeKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQ 495
Cdd:pfam15921  657 QLLNEVKTSRNELNSLSEDyEVLKrnFRNKSEEMETTTNKLKMQL-KSAQSELEQTRNTLKSMEGSDGHAMKVAMGMQKQ 735

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   496 IktiekTSEEERI-SLQQELSRVKQEVVDVMKKS---SEEQIAKLQKLH----EKELARKEQELTKKLQTREREFQEQMK 567
Cdd:pfam15921  736 I-----TAKRGQIdALQSKIQFLEEAMTNANKEKhflKEEKNKLSQELStvatEKNKMAGELEVLRSQERRLKEKVANME 810

                          410       420
                   ....*....|....*....|...
gi 530372322   568 VALEKSQSEYLK---ISQEKEQQ 587
Cdd:pfam15921  811 VALDKASLQFAEcqdIIQRQEQE 833
PRK12704 PRK12704
phosphodiesterase; Provisional
 958-1126 3.27e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 42.46  E-value: 3.27e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  958 KQILVEKENMILQMREGQKKEIEILTQK--LSAKEDsIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLDQEaK 1035
Cdd:PRK12704   30 EAKIKEAEEEAKRILEEAKKEAEAIKKEalLEAKEE-IHKLRNEFEKELRERRNELQKLEKRLLQKEENLDRKLELLE-K 107

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1036 LKKELENTALELSQKEKQFNAKMLEMAQAnsagISDAVSRLetnqkEQIESLTEVHRRELndVISIWEKKLNQQAEELqe 1115
Cdd:PRK12704  108 REEELEKKEKELEQKQQELEKKEEELEEL----IEEQLQEL-----ERISGLTAEEAKEI--LLEKVEEEARHEAAVL-- 174

                         170
                  ....*....|.
gi 530372322 1116 IHEIQLQEKEQ 1126
Cdd:PRK12704  175 IKEIEEEAKEE 185
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1977-2187 3.27e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.98  E-value: 3.27e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1977 EAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRK-------------------EHQQELEILKKEYDQERE-----E 2032
Cdd:COG4913   609 RAKLAALEAELAELEEELAEAEERLEALEAELDALQErrealqrlaeyswdeidvaSAEREIAELEAELERLDAssddlA 688

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 2033 KIKQEQEDLELKHNsTLKQLMREFNTQLAQKEQELEmTIKETINKAQEVEAELLESHQEETNQLL-KKIAEKDDDlkRTA 2111
Cdd:COG4913   689 ALEEQLEELEAELE-ELEEELDELKGEIGRLEKELE-QAEEELDELQDRLEAAEDLARLELRALLeERFAAALGD--AVE 764

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 2112 KRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEENPGN----DNTQLAQKTTLISDSKL--KEQEFREQIHNLE 2185
Cdd:COG4913   765 RELRENLEERIDALRARLNRAEEELERAMRAFNREWPAETADLDadleSLPEYLALLDRLEEDGLpeYEERFKELLNENS 844


                  ..
gi 530372322 2186 DR 2187
Cdd:COG4913   845 IE 846
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 375-934 3.49e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 42.85  E-value: 3.49e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   375 QEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIA------ETKRQMHETLEMKEEEIAQLRSRIKQ 448
Cdd:pfam01576   21 QQKAESELKELEKKHQQLCEEKNALQEQLQAETELCAEAEEMRARLAArkqeleEILHELESRLEEEEERSQQLQNEKKK 100

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   449 MTTQGEELREQKEKSERAafeelEKALSTAQKTEEARRKlkaEMDEQIKTIEktseEERISLQQELSRVKQEVVDVMKKS 528
Cdd:pfam01576  101 MQQHIQDLEEQLDEEEAA-----RQKLQLEKVTTEAKIK---KLEEDILLLE----DQNSKLSKERKLLEERISEFTSNL 168

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   529 SEEQ-----IAKLQKLHEKELARKEQELTKKLQTRERefQEQMKVALEKSQSEYlkisqekeQQESLALEELELQKKAIL 603
Cdd:pfam01576  169 AEEEekaksLSKLKNKHEAMISDLEERLKKEEKGRQE--LEKAKRKLEGESTDL--------QEQIAELQAQIAELRAQL 238

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   604 TESENKLRDLQQEAETYRTRilelESSLEKSLQENKNQSKDLAVHLEAEKNKHNKeitvmVEKHKTELEslkHQQDALWT 683
Cdd:pfam01576  239 AKKEEELQAALARLEEETAQ----KNNALKKIRELEAQISELQEDLESERAARNK-----AEKQRRDLG---EELEALKT 306

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   684 EKLQVLKQQyqTEMEKLREKCEQEKETL---LKDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEE 760
Cdd:pfam01576  307 ELEDTLDTT--AAQQELRSKREQEVTELkkaLEEETRSHEAQLQEMRQKHTQALEELTEQLEQAKRNKANLEKAKQALES 384

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   761 ELSVLKDQTDKMKQeleAKMDEQknHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLlkerdkhlkehQAHVENLEAD 840
Cdd:pfam01576  385 ENAELQAELRTLQQ---AKQDSE--HKRKKLEGQLQELQARLSESERQRAELAEKLSKL-----------QSELESVSSL 448

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   841 IKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQD 920
Cdd:pfam01576  449 LNEAEGKNIKLSKDVSSLESQLQDTQELLQEETRQKLNLSTRLRQLEDERNSLQEQLEEEEEAKRNVERQLSTLQAQLSD 528

                          570
                   ....*....|....
gi 530372322   921 LMQQLEKQNSEMEQ 934
Cdd:pfam01576  529 MKKKLEEDAGTLEA 542
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1565-1743 3.78e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 42.59  E-value: 3.78e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1565 EKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIE--HKELVQKLQHFQELgEEKDNRVKEAEEKI 1642
Cdd:COG4913   616 EAELAELEEELAEAEERLEALEAELDALQERREALQRLAEYSWDEIDVAsaEREIAELEAELERL-DASSDDLAALEEQL 694

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1643 LTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKqllsqmEEKEEQYK 1722
Cdd:COG4913   695 EELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAALG------DAVERELR 768

                         170       180
                  ....*....|....*....|.
gi 530372322 1723 KGTESHLSELNTKLQEREREV 1743
Cdd:COG4913   769 ENLEERIDALRARLNRAEEEL 789
PRK09039 PRK09039
peptidoglycan -binding protein;
389-553 3.95e-03

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 41.88  E-value: 3.95e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  389 KDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAetkrQMHETLEMKEEEiaqlRSRIKQMTTQGEELREQKEKseRAAf 468
Cdd:PRK09039   51 KDSALDRLNSQIAELADLLSLERQGNQDLQDSVA----NLRASLSAAEAE----RSRLQALLAELAGAGAAAEG--RAG- 119

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  469 eELEKALSTAQKT-EEARRKLkAEMDEQIKtiektseeeriSLQQELSRVkQEVVDVMKKSSEEQIAKLQKLHEK---EL 544
Cdd:PRK09039  120 -ELAQELDSEKQVsARALAQV-ELLNQQIA-----------ALRRQLAAL-EAALDASEKRDRESQAKIADLGRRlnvAL 185


                  ....*....
gi 530372322  545 ARKEQELTK 553
Cdd:PRK09039  186 AQRVQELNR 194
PRK02224 PRK02224
DNA double-strand break repair Rad50 ATPase;
173-651 4.21e-03

DNA double-strand break repair Rad50 ATPase;


Pssm-ID: 179385 [Multi-domain]  Cd Length: 880  Bit Score: 42.33  E-value: 4.21e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  173 SDMDSEAEDLVGNS--DSLNKEQLIQRLRRMERSLSSYRGKYSELVTAYQMLQREKKKLQGilsqsqdkslrRIAELREE 250
Cdd:PRK02224  289 EELEEERDDLLAEAglDDADAEAVEARREELEDRDEELRDRLEECRVAAQAHNEEAESLRE-----------DADDLEER 357

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  251 LQMDQQAKKHLQEEFDAS---LEEKDQYISVLQTQVSLLKQRLRNGPMNVDvlkplpqlepqaEVFTKEENPESDGEPVV 327
Cdd:PRK02224  358 AEELREEAAELESELEEAreaVEDRREEIEELEEEIEELRERFGDAPVDLG------------NAEDFLEELREERDELR 425

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  328 EDGTSVK-TLETLQQRVKRQENLLK--RCKETIQSHKEQ---CTLltSEKEALQEQLDERLQELEkikdLHMAEKTKLIT 401
Cdd:PRK02224  426 EREAELEaTLRTARERVEEAEALLEagKCPECGQPVEGSphvETI--EEDRERVEELEAELEDLE----EEVEEVEERLE 499

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  402 QLRDAKNLIEQLEQDKgmviaetkrqmhETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKT 481
Cdd:PRK02224  500 RAEDLVEAEDRIERLE------------ERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEA 567

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  482 EEARRKLK------AEMDEQIKTIEK--TSEEERISLQQELSRVKQevvdvmkksseeqiaKLQKLHEKELARKEQELTK 553
Cdd:PRK02224  568 EEAREEVAelnsklAELKERIESLERirTLLAAIADAEDEIERLRE---------------KREALAELNDERRERLAEK 632

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  554 KLQTREREfqeqmkvalEKSQSEYLKISQEKEQQEslaleelelqkKAILTESENKLRDLQQEAETYRTRILELESSLEk 633
Cdd:PRK02224  633 RERKRELE---------AEFDEARIEEAREDKERA-----------EEYLEQVEEKLDELREERDDLQAEIGAVENELE- 691

                         490
                  ....*....|....*...
gi 530372322  634 SLQENKNQSKDLAVHLEA 651
Cdd:PRK02224  692 ELEELRERREALENRVEA 709
46 PHA02562
endonuclease subunit; Provisional
 1533-1746 4.39e-03

endonuclease subunit; Provisional


Pssm-ID: 222878 [Multi-domain]  Cd Length: 562  Bit Score: 42.31  E-value: 4.39e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1533 DEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQQK-D 1611
Cdd:PHA02562  187 DMKIDHIQQQIKTYNKNIEEQRKKNGENIARKQNKYDELVEEAKTIKAEIEELTDELLNLVMDIEDPSAALNKLNTAAaK 266

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1612 IEHK-ELVQKLQHFQELGEE---KDNRVKEAEEKIltlenqvysmkAELETKKKELEHVNLSVKSKEEELKALEDRLeSE 1687
Cdd:PHA02562  267 IKSKiEQFQKVIKMYEKGGVcptCTQQISEGPDRI-----------TKIKDKLKELQHSLEKLDTAIDELEEIMDEF-NE 334

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 530372322 1688 SAAKLAELKRKAEQKIAAIK------KQLLSQMEEKEEQYK------KGTESHLSELNTKLQEREREVHIL 1746
Cdd:PHA02562  335 QSKKLLELKNKISTNKQSLItlvdkaKKVKAAIEELQAEFVdnaeelAKLQDELDKIVKTKSELVKEKYHR 405
Myosin_tail_1 pfam01576
Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and ...
 648-1720 4.49e-03

Myosin tail; The myosin molecule is a multi-subunit complex made up of two heavy chains and four light chains it is a fundamental contractile protein found in all eukaryote cell types. This family consists of the coiled-coil myosin heavy chain tail region. The coiled-coil is composed of the tail from two molecules of myosin. These can then assemble into the macromolecular thick filament. The coiled-coil region provides the structural backbone the thick filament.


Pssm-ID: 460256 [Multi-domain]  Cd Length: 1081  Bit Score: 42.47  E-value: 4.49e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   648 HLEAEKNKHNKEITVMVEKHKTELESLKHQQDALWTEK------LQVLKQQYQTEMEKLREKCEQEKETL--LKDKEIIF 719
Cdd:pfam01576   50 QAETELCAEAEEMRARLAARKQELEEILHELESRLEEEeersqqLQNEKKKMQQHIQDLEEQLDEEEAARqkLQLEKVTT 129

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   720 QAHIEEMNEKTLEKLDvkqteleslssELSEVLKARHKLEEELSvlkDQTDKMKQELEAKMDEQKNHHQQQvdSIIKEHE 799
Cdd:pfam01576  130 EAKIKKLEEDILLLED-----------QNSKLSKERKLLEERIS---EFTSNLAEEEEKAKSLSKLKNKHE--AMISDLE 193

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   800 VSIQRTEKALKDQIN---QLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDvfqSYQSATHEQTKAYEEQL 876
Cdd:pfam01576  194 ERLKKEEKGRQELEKakrKLEGESTDLQEQIAELQAQIAELRAQLAKKEEELQAALARLE---EETAQKNNALKKIRELE 270

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   877 AQLQQKLLDLETERILLTKqvaeVEAQKKDVCTELDAHKIQV----------QDLMQQLEKQNSEMEQKVKSLTQVYESK 946
Cdd:pfam01576  271 AQISELQEDLESERAARNK----AEKQRRDLGEELEALKTELedtldttaaqQELRSKREQEVTELKKALEEETRSHEAQ 346

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   947 LEDGNKEQEQTKQILVEKENMILQMR---EGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEmQE 1023
Cdd:pfam01576  347 LQEMRQKHTQALEELTEQLEQAKRNKanlEKAKQALESENAELQAELRTLQQAKQDSEHKRKKLEGQLQELQARLSE-SE 425

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1024 TLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAgISDAVSRLETNQKEQIESLTEVhrRELNDVISIWE 1103
Cdd:pfam01576  426 RQRAELAEKLSKLQSELESVSSLLNEAEGKNIKLSKDVSSLESQ-LQDTQELLQEETRQKLNLSTRL--RQLEDERNSLQ 502

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1104 KKLNQQAEELQEIhEIQLQEKEQEVAELKQKIllfgcekEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQD 1183
Cdd:pfam01576  503 EQLEEEEEAKRNV-ERQLSTLQAQLSDMKKKL-------EEDAGTLEALEEGKKRLQRELEALTQQLEEKAAAYDKLEKT 574

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1184 ETKLKAHLEKLEVDLNKslkentflQEQLVelkmlaeedkrkvseltsklkttdeefqslkSSHEKSNKSLEdkslefKK 1263
Cdd:pfam01576  575 KNRLQQELDDLLVDLDH--------QRQLV-------------------------------SNLEKKQKKFD------QM 609

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1264 LSEELAIQLDICCKKTEALLEAKTNELINISSSKtnailsrishcqhrttkvkeALLIKTCTVSELEAQLRQLTEEQNTL 1343
Cdd:pfam01576  610 LAEEKAISARYAEERDRAEAEAREKETRALSLAR--------------------ALEEALEAKEELERTNKQLRAEMEDL 669

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1344 NISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLKKELSENINAvtlmkeELKEKKVE 1423
Cdd:pfam01576  670 VSSKDDVGKNVHELERSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNMQALKAQFERDLQA------RDEQGEEK 743

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1424 ISSLSKQLTDLNVQLQNSislSEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKK 1503
Cdd:pfam01576  744 RRQLVKQVRELEAELEDE---RKQRAQAVAAKKKLELDLKELEAQIDAANKGREEAVKQLKKLQAQMKDLQRELEEARAS 820

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1504 AQSRFTQHQNTVKELQ------IQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKS 1577
Cdd:pfam01576  821 RDEILAQSKESEKKLKnleaelLQLQEDLAASERARRQAQQERDELADEIASGASGKSALQDEKRRLEARIAQLEEELEE 900

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1578 QTARIMELEDHITQKTIEIESLNEVL----------KNYNQQKDIEHKELVQKLQHFQELGEEKdnrvkeAEEKILTLEN 1647
Cdd:pfam01576  901 EQSNTELLNDRLRKSTLQVEQLTTELaaerstsqksESARQQLERQNKELKAKLQEMEGTVKSK------FKSSIAALEA 974

                         1050      1060      1070      1080      1090      1100      1110
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 530372322  1648 QVYSMKAELETKKKELEHVNLSVKSKEEELKalEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQ 1720
Cdd:pfam01576  975 KIAQLEEQLEQESRERQAANKLVRRTEKKLK--EVLLQVEDERRHADQYKDQAEKGNSRMKQLKRQLEEAEEE 1045
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 1986-2203 4.54e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 41.67  E-value: 4.54e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1986 KLAGAEREKQKLGKEIVRLQKDLRMLRKEH---QQELEILKKEYDQ--EREEKIKQEQEDLELKHNSTLKQLmREFNTQL 2060
Cdd:COG4942    21 AAAEAEAELEQLQQEIAELEKELAALKKEEkalLKQLAALERRIAAlaRRIRALEQELAALEAELAELEKEI-AELRAEL 99

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 2061 AQKEQELEMTIKETINKAQEVEAELLESHQEET---------NQLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAKVRD 2131
Cdd:COG4942   100 EAQKEELAELLRALYRLGRQPPLALLLSPEDFLdavrrlqylKYLAPARREQAEELRADLAELAALRAELEAERAELEAL 179

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 530372322 2132 LQTQLEELQKKYQQKLEQEENPGNDNTQLAQKTTLISDSKLKEQEFREQIHNLEDRLKKYEKNVYATTVGTP 2203
Cdd:COG4942   180 LAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAERTPAAGFAAL 251
PRK12704 PRK12704
phosphodiesterase; Provisional
 1688-1864 4.64e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 42.07  E-value: 4.64e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1688 SAAKLAELKRKAEQKIA-------AIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKsvesSQSET 1760
Cdd:PRK12704   29 AEAKIKEAEEEAKRILEeakkeaeAIKKEALLEAKEEIHKLRNEFEKELRERRNELQKLEKRLLQKEENLD----RKLEL 104

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1761 LivprSAKNVAAYTEQEEADSQgcvQKTYEEKISVLQRNLTEKEKLLQRV-GQEKEETvsshfemrcqyqeRLIKLEHAE 1839
Cdd:PRK12704  105 L----EKREEELEKKEKELEQK---QQELEKKEEELEELIEEQLQELERIsGLTAEEA-------------KEILLEKVE 164

                         170       180
                  ....*....|....*....|....*.
gi 530372322 1840 AK-QHEDQSMIGHLQEELEEKNKKYS 1864
Cdd:PRK12704  165 EEaRHEAAVLIKEIEEEAKEEADKKA 190
PRK12704 PRK12704
phosphodiesterase; Provisional
 404-543 4.80e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 42.07  E-value: 4.80e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  404 RDAKNLIEQLEQDKGMVIAETKRQMHEtleMKEEEIAQLRSRIKQMTTQGE-ELRE------QKEKSERAAFEELEKALS 476
Cdd:PRK12704   27 KIAEAKIKEAEEEAKRILEEAKKEAEA---IKKEALLEAKEEIHKLRNEFEkELRErrnelqKLEKRLLQKEENLDRKLE 103

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 530372322  477 TAQKTEEARRKLKAEMDEQIKTIEKTSEE-ERISLQQ--ELSRV--------KQEVVDVMKKSSEEQIAKLQKLHEKE 543
Cdd:PRK12704  104 LLEKREEELEKKEKELEQKQQELEKKEEElEELIEEQlqELERIsgltaeeaKEILLEKVEEEARHEAAVLIKEIEEE 181
HlpA COG2825
Periplasmic chaperone for outer membrane proteins, Skp family [Cell wall/membrane/envelope ...
 1991-2078 4.81e-03

Periplasmic chaperone for outer membrane proteins, Skp family [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 442073 [Multi-domain]  Cd Length: 171  Bit Score: 40.20  E-value: 4.81e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1991 EREKQKLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDlelkhnstLKQLMREFNTQLAQKEQELEMT 2070
Cdd:COG2825    49 EKEFKKRQAELQKLEKELQALQEKLQKEAATLSEEERQKKERELQKKQQE--------LQRKQQEAQQDLQKRQQELLQP 120


                  ....*...
gi 530372322 2071 IKETINKA 2078
Cdd:COG2825   121 ILEKIQKA 128
PTZ00108 PTZ00108
DNA topoisomerase 2-like protein; Provisional
 367-638 4.97e-03

DNA topoisomerase 2-like protein; Provisional


Pssm-ID: 240271 [Multi-domain]  Cd Length: 1388  Bit Score: 42.34  E-value: 4.97e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  367 LTSEK-EALQEQLDERLQELEKIKdlhmaeKTKLITQ-LRDAKNLIEQLEQDKGMViaETKRQMHETLEMKEEEIaQLRS 444
Cdd:PTZ00108 1099 LTKEKvEKLNAELEKKEKELEKLK------NTTPKDMwLEDLDKFEEALEEQEEVE--EKEIAKEQRLKSKTKGK-ASKL 1169

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  445 RIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEqiKTIEKTSEEERISLQQELSRVKQEVVDV 524
Cdd:PTZ00108 1170 RKPKLKKKEKKKKKSSADKSKKASVVGNSKRVDSDEKRKLDDKPDNKKSN--SSGSDQEDDEEQKTKPKKSSVKRLKSKK 1247

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  525 MKKSSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQ------SEYLKISQEKEQQESLALEELELQ 598
Cdd:PTZ00108 1248 NNSSKSSEDNDEFSSDDLSKEGKPKNAPKRVSAVQYSPPPPSKRPDGESNggskpsSPTKKKVKKRLEGSLAALKKKKKS 1327

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|
gi 530372322  599 KKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQEN 638
Cdd:PTZ00108 1328 EKKTARKKKSKTRVKQASASQSSRLLRRPRKKKSDSSSED 1367
Cast pfam10174
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ...
 822-1255 5.26e-03

RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.


Pssm-ID: 431111 [Multi-domain]  Cd Length: 766  Bit Score: 42.12  E-value: 5.26e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   822 ERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSAThEQTKAYEeqlaqlqQKLLDLETERILLTKQVAEVE 901
Cdd:pfam10174  182 ERTRRIAEAEMQLGHLEVLLDQKEKENIHLREELHRRNQLQPDP-AKTKALQ-------TVIEMKDTKISSLERNIRDLE 253

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   902 AQKKDVCTELDAHKIQVQDLMQQLEKQNSE---MEQKVKSLTQvyesklEDGNKEQEQtkQILVEKENMILQMREGQKKE 978
Cdd:pfam10174  254 DEVQMLKTNGLLHTEDREEEIKQMEVYKSHskfMKNKIDQLKQ------ELSKKESEL--LALQTKLETLTNQNSDCKQH 325

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   979 IEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQET-------------LKKKLLDQEAK---LKKELEN 1042
Cdd:pfam10174  326 IEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLteekstlageirdLKDMLDVKERKinvLQKKIEN 405

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1043 TALELSQKEKQFnakmlemaqansAGISDAVSRLETNQKEQIESLTEvhrreLNDVISIWEKKLnqqaEELQEIHEIQLQ 1122
Cdd:pfam10174  406 LQEQLRDKDKQL------------AGLKERVKSLQTDSSNTDTALTT-----LEEALSEKERII----ERLKEQREREDR 464

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1123 EKEQEVAELKQkillfgcEKEEMNKEITWLKEEGVKQDTTLNELQEqlkqksaHVNSLAQDETKLKAHLEKLEVDLNKSL 1202
Cdd:pfam10174  465 ERLEELESLKK-------ENKDLKEKVSALQPELTEKESSLIDLKE-------HASSLASSGLKKDSKLKSLEIAVEQKK 530

                          410       420       430       440       450
                   ....*....|....*....|....*....|....*....|....*....|...
gi 530372322  1203 KENTFLQEQLVELKMlAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSLE 1255
Cdd:pfam10174  531 EECSKLENQLKKAHN-AEEAVRTNPEINDRIRLLEQEVARYKEESGKAQAEVE 582
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 192-775 5.33e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 41.98  E-value: 5.33e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   192 EQLIQRLRRMERSLSSYRGKYSELVTAYQMLQREKKKLQGILSQSQDKSLR---RIAELREELQMDQQAKKHLQ---EEF 265
Cdd:TIGR02169  367 EDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQEELQRlseELADLNAAIAGIEAKINELEeekEDK 446

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   266 DASLEEKDQYISVLQTQVSLLKQRLRNGPMNVDVL--------KPLPQLEPQAEVFTKEENPESDGEPVVEDGTS----- 332
Cdd:TIGR02169  447 ALEIKKQEWKLEQLAADLSKYEQELYDLKEEYDRVekelsklqRELAEAEAQARASEERVRGGRAVEEVLKASIQgvhgt 526

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   333 -----------VKTLET-----LQQRVKRQENLLKRCKETIQSHK-EQCTLLTSEKEALQEQLDERLQELEKIKDLhmae 395
Cdd:TIGR02169  527 vaqlgsvgeryATAIEVaagnrLNNVVVEDDAVAKEAIELLKRRKaGRATFLPLNKMRDERRDLSILSEDGVIGFA---- 602

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   396 kTKLITQLRDAKNLIEQLEQDKGMV--IAETKRQMHE----TLE-------------------------MKEEEIAQLRS 444
Cdd:TIGR02169  603 -VDLVEFDPKYEPAFKYVFGDTLVVedIEAARRLMGKyrmvTLEgelfeksgamtggsraprggilfsrSEPAELQRLRE 681

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   445 RIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKA--EMDEQIKTIEKTSEEERISLQQELSRVKQEVV 522
Cdd:TIGR02169  682 RLEGLKRELSSLQSELRRIENRLDELSQELSDASRKIGEIEKEIEQleQEEEKLKERLEELEEDLSSLEQEIENVKSELK 761

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   523 DVMKKSS--EEQIAKLQKLHEKELARKEQELTKKLQtREREFQEQMKVALEKSQSEyLKISQEKEQQESLALEELELQKK 600
Cdd:TIGR02169  762 ELEARIEelEEDLHKLEEALNDLEARLSHSRIPEIQ-AELSKLEEEVSRIEARLRE-IEQKLNRLTLEKEYLEKEIQELQ 839

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   601 AILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAvHLEAEKNKHNKEITVM---VEKHKTELESLKHQ 677
Cdd:TIGR02169  840 EQRIDLKEQIKSIEKEIENLNGKKEELEEELEELEAALRDLESRLG-DLKKERDELEAQLRELerkIEELEAQIEKKRKR 918

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   678 QDALwTEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKeiiFQAHIEEMNE--KTLEKLDVKQTELESLSSELSEVLKAR 755
Cdd:TIGR02169  919 LSEL-KAKLEALEEELSEIEDPKGEDEEIPEEELSLED---VQAELQRVEEeiRALEPVNMLAIQEYEEVLKRLDELKEK 994

                          650       660
                   ....*....|....*....|.
gi 530372322   756 H-KLEEELSVLKDQTDKMKQE 775
Cdd:TIGR02169  995 RaKLEEERKAILERIEEYEKK 1015
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1671-1945 5.50e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 42.03  E-value: 5.50e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1671 KSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKL 1750
Cdd:pfam17380  290 QEKFEKMEQERLRQEKEEKAREVERRRKLEEAEKARQAEMDRQAAIYAEQERMAMERERELERIRQEERKRELERIRQEE 369

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1751 KSVESS---QSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYeekisvlQRNLTEKEKLLQRVGQEKEEtvSSHFEMRCQ 1827
Cdd:pfam17380  370 IAMEISrmrELERLQMERQQKNERVRQELEAARKVKILEEER-------QRKIQQQKVEMEQIRAEQEE--ARQREVRRL 440

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1828 YQERLIKLEHAEAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEKEGGKNniQAKQNLENVFDDVQKTLQEKELTCQIL 1907
Cdd:pfam17380  441 EEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKRDRKRAEE--QRRKILEKELEERKQAMIEEERKRKLL 518

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|
gi 530372322  1908 EQKIKELDSCLVRQKEVHRVEMEELTSK--YEKLQALQQM 1945
Cdd:pfam17380  519 EKEMEERQKAIYEEERRREAEEERRKQQemEERRRIQEQM 558
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 529-907 5.51e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 41.98  E-value: 5.51e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   529 SEEQIAKLQKLHEK--ELARKEQELTKKLQTREREFQEqMKVALEKSQSEYLKISQEKEQqeslaLEELELQKKAILTES 606
Cdd:TIGR02169  669 SRSEPAELQRLRERleGLKRELSSLQSELRRIENRLDE-LSQELSDASRKIGEIEKEIEQ-----LEQEEEKLKERLEEL 742

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   607 ENKLRDLQQEAETYRTRILELESSLEKsLQENKNQSKDLAVHLEAEKNKHN-KEITVMVEKHKTELESLKHQQDAL--WT 683
Cdd:TIGR02169  743 EEDLSSLEQEIENVKSELKELEARIEE-LEEDLHKLEEALNDLEARLSHSRiPEIQAELSKLEEEVSRIEARLREIeqKL 821

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   684 EKLQVLKQQYQTEMEKLrekceQEKETLLKDKEIIFQAHIEEMN---EKTLEKLDVKQTELESLSSELSEVLKARHKLEE 760
Cdd:TIGR02169  822 NRLTLEKEYLEKEIQEL-----QEQRIDLKEQIKSIEKEIENLNgkkEELEEELEELEAALRDLESRLGDLKKERDELEA 896

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   761 ELSVLKDQtdkmKQELEAKMDEQKNHHQQQvdsiikehevsiQRTEKALKDQINQLELLLKErDKHLKEHQAHVENLEAD 840
Cdd:TIGR02169  897 QLRELERK----IEELEAQIEKKRKRLSEL------------KAKLEALEEELSEIEDPKGE-DEEIPEEELSLEDVQAE 959

                          330       340       350       360       370       380
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 530372322   841 IKRSEGELQQasakldvFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDV 907
Cdd:TIGR02169  960 LQRVEEEIRA-------LEPVNMLAIQEYEEVLKRLDELKEKRAKLEEERKAILERIEEYEKKKREV 1019
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1974-2150 5.69e-03

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 41.93  E-value: 5.69e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1974 SNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEH---------QQELEILKkEYDQEREEkIKQEQEDLELK 2044
Cdd:COG3206   164 QNLELRREEARKALEFLEEQLPELRKELEEAEAALEEFRQKNglvdlseeaKLLLQQLS-ELESQLAE-ARAELAEAEAR 241

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 2045 HNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLESHQEETNQ---LLKKIAEKDDDLKRTAKRYEEILDAR 2121
Cdd:COG3206   242 LAALRAQLGSGPDALPELLQSPVIQQLRAQLAELEAELAELSARYTPNHPDviaLRAQIAALRAQLQQEAQRILASLEAE 321

                         170       180       190
                  ....*....|....*....|....*....|.
gi 530372322 2122 EEEMTAKVRDLQTQLEELQKKYQQ--KLEQE 2150
Cdd:COG3206   322 LEALQAREASLQAQLAQLEARLAElpELEAE 352
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 545-1380 6.15e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 41.98  E-value: 6.15e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   545 ARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKIsqEKEQQESLALEELELQKKAiLTESENKLRDLQQEAETYRTRI 624
Cdd:TIGR02169  170 RKKEKALEELEEVEENIERLDLIIDEKRQQLERLRR--EREKAERYQALLKEKREYE-GYELLKEKEALERQKEAIERQL 246

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   625 LELESSLEKS---LQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKHQQDALwtEKLQVLKQQYQTEMEKLR 701
Cdd:TIGR02169  247 ASLEEELEKLteeISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGELEAEIASL--ERSIAEKERELEDAEERL 324

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   702 EKCEQEKETLLKDKEIIfqahieemnEKTLEKLDVKqteleslsselsevlkaRHKLEEELSVLKDQTDKMKQELEAKMD 781
Cdd:TIGR02169  325 AKLEAEIDKLLAEIEEL---------EREIEEERKR-----------------RDKLTEEYAELKEELEDLRAELEEVDK 378

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   782 EQKNHHQQQVDSIIKEHEVSIQRTEkaLKDQINQLELLLKERDKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSY 861
Cdd:TIGR02169  379 EFAETRDELKDYREKLEKLKREINE--LKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWK 456

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   862 QSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVqdlmQQLEKQNSEMEQKVKSLTQ 941
Cdd:TIGR02169  457 LEQLAADLSKYEQELYDLKEEYDRVEKELSKLQRELAEAEAQARASEERVRGGRAVE----EVLKASIQGVHGTVAQLGS 532

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   942 V---YESKLE--DGNKEQE---QTKQILVEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNE---------EYETKF 1004
Cdd:TIGR02169  533 VgerYATAIEvaAGNRLNNvvvEDDAVAKEAIELLKRRKAGRATFLPLNKMRDERRDLSILSEDGvigfavdlvEFDPKY 612

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1005 KNQEKK-------MEKVKQKAKEMQE----TLKKKLLDQE------AKLKKELENTALELSQKEKQFNAKMLEMaQANSA 1067
Cdd:TIGR02169  613 EPAFKYvfgdtlvVEDIEAARRLMGKyrmvTLEGELFEKSgamtggSRAPRGGILFSRSEPAELQRLRERLEGL-KRELS 691

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1068 GISDAVSRLETNQKEQIESLTEVHR--RELNDVISIWEKKLNQQAEELQEIhEIQLQEKEQEVAELKQkillfgcEKEEM 1145
Cdd:TIGR02169  692 SLQSELRRIENRLDELSQELSDASRkiGEIEKEIEQLEQEEEKLKERLEEL-EEDLSSLEQEIENVKS-------ELKEL 763

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1146 NKEITWLKEEGVKQDTTLNEL-----QEQLKQKSAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAE 1220
Cdd:TIGR02169  764 EARIEELEEDLHKLEEALNDLearlsHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEYLEKEIQELQEQRI 843

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1221 EDKRKVSELTSK---LKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKLSEELAIQLDICCKKTEALLEA--KTNELINISS 1295
Cdd:TIGR02169  844 DLKEQIKSIEKEienLNGKKEELEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQieKKRKRLSELK 923

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1296 SKTNAILSRISHCQhrtTKVKEALLIKTCTVSE--LEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVT 1373
Cdd:TIGR02169  924 AKLEALEEELSEIE---DPKGEDEEIPEEELSLedVQAELQRVEEEIRALEPVNMLAIQEYEEVLKRLDELKEKRAKLEE 1000


                   ....*..
gi 530372322  1374 EKEALQK 1380
Cdd:TIGR02169 1001 ERKAILE 1007
sbcc TIGR00618
exonuclease SbcC; All proteins in this family for which functions are known are part of an ...
 363-1133 6.22e-03

exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129705 [Multi-domain]  Cd Length: 1042  Bit Score: 41.88  E-value: 6.22e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   363 QCTLLTSEKEALQEQLDERLQELEKIKDLHMAEKTKLiTQLRDAKNLIEQLEQDKGMVIAETKRQMHETLEMKEEEIAQL 442
Cdd:TIGR00618  153 EFAQFLKAKSKEKKELLMNLFPLDQYTQLALMEFAKK-KSLHGKAELLTLRSQLLTLCTPCMPDTYHERKQVLEKELKHL 231

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   443 RSRIKQMTTQGEELREQKEKSERAafEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQElsrvkqevv 522
Cdd:TIGR00618  232 REALQQTQQSHAYLTQKREAQEEQ--LKKQQLLKQLRARIEELRAQEAVLEETQERINRARKAAPLAAHIK--------- 300

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   523 dvmkksSEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVAlEKSQSEYLKISQEKEQQESLALEELELQKKAI 602
Cdd:TIGR00618  301 ------AVTQIEQQAQRIHTELQSKMRSRAKLLMKRAAHVKQQSSIE-EQRRLLQTLHSQEIHIRDAHEVATSIREISCQ 373

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   603 LTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLkHQQDALW 682
Cdd:TIGR00618  374 QHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQRYAELCAA-AITCTAQ 452

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   683 TEKLQVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNE-KTLEKLDVKQTELESLSSELSEVLKARHKLEEE 761
Cdd:TIGR00618  453 CEKLEKIHLQESAQSLKEREQQLQTKEQIHLQETRKKAVVLARLLElQEEPCPLCGSCIHPNPARQDIDNPGPLTRRMQR 532

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   762 LSVLKDQTDKMKQELEAKMDEQKNHHQqqvdsIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHVENLEADI 841
Cdd:TIGR00618  533 GEQTYAQLETSEEDVYHQLTSERKQRA-----SLKEQMQEIQQSFSILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAE 607

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   842 KRSEGELQQASAKLDVFQS-YQSATHEQTKAYEEQLAqlqqklldleteriLLTKQVAEVEAQKKDVCTELDAHKIQVQD 920
Cdd:TIGR00618  608 DMLACEQHALLRKLQPEQDlQDVRLHLQQCSQELALK--------------LTALHALQLTLTQERVREHALSIRVLPKE 673

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   921 LMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQEQTkqilvEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEY 1000
Cdd:TIGR00618  674 LLASRQLALQKMQSEKEQLTYWKEMLAQCQTLLRELE-----THIEEYDREFNEIENASSSLGSDLAAREDALNQSLKEL 748

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1001 ETKFKNQEKKMEKVKQKAKEmQETLKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQ 1080
Cdd:TIGR00618  749 MHQARTVLKARTEAHFNNNE-EVTAALQTGAELSHLAAEIQFFNRLREEDTHLLKTLEAEIGQEIPSDEDILNLQCETLV 827

                          730       740       750       760       770
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 530372322  1081 KEQIESLTEVHRR-----ELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQ 1133
Cdd:TIGR00618  828 QEEEQFLSRLEEKsatlgEITHQLLKYEECSKQLAQLTQEQAKIIQLSDKLNGINQIK 885
Nup88 pfam10168
Nuclear pore component; Nup88 can be divided into two structural domains; the N-terminal ...
 307-539 6.77e-03

Nuclear pore component; Nup88 can be divided into two structural domains; the N-terminal two-thirds of the protein has no obvious structural motifs but is the region for binding to Nup98, one of the components of the nuclear pore. the C-terminal end is a predicted coiled-coil domain. Nup88 is overexpressed in tumour cells.


Pssm-ID: 462975 [Multi-domain]  Cd Length: 713  Bit Score: 41.57  E-value: 6.77e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   307 EPQAEVFTKEENPESDGEPVVEDGTS-VKTLETLQQRVKRQEnLLKRCKETIQSHKEQCTLLTSEKEALQEQLDERlqel 385
Cdd:pfam10168  477 PPSPPLLCSKEDVTVDEPLRGLQEDSfEDHIKSILQRSVSNP-ILSADKLSSPSPQECLQLLSRATQVFREEYLKK---- 551

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   386 ekiKDLHMAEKTKLITQLRDAKnliEQLEQDKGMVIAETK--RQMHETLEMKEEEIAQ----LRSRIKQMTTQGEELREQ 459
Cdd:pfam10168  552 ---HDLAREEIQKRVKLLKLQK---EQQLQELQSLEEERKslSERAEKLAEKYEEIKDkqekLMRRCKKVLQRLNSQLPV 625

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322   460 KEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEER---ISLQQELSRVKQEVVDVMKKSSEEQIAKL 536
Cdd:pfam10168  626 LSDAEREMKKELETINEQLKHLANAIKQAKKKMNYQRYQIAKSQSIRKkssLSLSEKQRKTIKEILKQLGSEIDELIKQV 705


                   ...
gi 530372322   537 QKL 539
Cdd:pfam10168  706 KDI 708
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 897-1015 6.94e-03

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 41.74  E-value: 6.94e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  897 VAEVEAQKKdvctELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKE-QEQTKQILVEKENMILQMREGQ 975
Cdd:PRK00409  522 IASLEELER----ELEQKAEEAEALLKEAEKLKEELEEKKEKLQEEEDKLLEEAEKEaQQAIKEAKKEADEIIKELRQLQ 597

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 530372322  976 KKEI-EILTQKLSAKEDSIHILNEEYETKFKNQEKKMEKVK 1015
Cdd:PRK00409  598 KGGYaSVKAHELIEARKRLNKANEKKEKKKKKQKEKQEELK 638
PRK00409 PRK00409
recombination and DNA strand exchange inhibitor protein; Reviewed
 1626-1754 7.00e-03

recombination and DNA strand exchange inhibitor protein; Reviewed


Pssm-ID: 234750 [Multi-domain]  Cd Length: 782  Bit Score: 41.74  E-value: 7.00e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1626 ELGEEKDnrvkEAEEKILTLENQvysmKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAA 1705
Cdd:PRK00409  510 LIGEDKE----KLNELIASLEEL----ERELEQKAEEAEALLKEAEKLKEELEEKKEKLQEEEDKLLEEAEKEAQQAIKE 581

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 530372322 1706 IKK---QLLSQMEEKEEQYKKGTESH-----LSELNTKLQEREREVHILEEKLKSVE 1754
Cdd:PRK00409  582 AKKeadEIIKELRQLQKGGYASVKAHelieaRKRLNKANEKKEKKKKKQKEKQEELK 638
PRK12704 PRK12704
phosphodiesterase; Provisional
 1994-2125 7.10e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 41.30  E-value: 7.10e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1994 KQKLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLKQLMREFNtQLAQKEQELEMtike 2073
Cdd:PRK12704   26 KKIAEAKIKEAEEEAKRILEEAKKEAEAIKKEALLEAKEEIHKLRNEFEKELRERRNELQKLEK-RLLQKEENLDR---- 100

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 530372322 2074 tinkaqevEAELLESHQEETNQLLKKIAEKDDDLKRTAKRYEEILDAREEEM 2125
Cdd:PRK12704  101 --------KLELLEKREEELEKKEKELEQKQQELEKKEEELEELIEEQLQEL 144
CwlO1 COG3883
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ...
 1326-1507 7.57e-03

Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];


Pssm-ID: 443091 [Multi-domain]  Cd Length: 379  Bit Score: 40.97  E-value: 7.57e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1326 VSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLK----- 1400
Cdd:COG3883    32 LEAAQAELDALQAELEELNEEYNELQAELEALQAEIDKLQAEIAEAEAEIEERREELGERARALYRSGGSVSYLDvllgs 111

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1401 KELSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQnsiSLSEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLS 1480
Cdd:COG3883   112 ESFSDFLDRLSALSKIADADADLLEELKADKAELEAKKA---ELEAKLAELEALKAELEAAKAELEAQQAEQEALLAQLS 188

                         170       180
                  ....*....|....*....|....*..
gi 530372322 1481 KEKISALEQVDDWSNKFSEWKKKAQSR 1507
Cdd:COG3883   189 AEEAAAEAQLAELEAELAAAEAAAAAA 215
COG5022 COG5022
Myosin heavy chain [General function prediction only];
345-847 7.85e-03

Myosin heavy chain [General function prediction only];


Pssm-ID: 227355 [Multi-domain]  Cd Length: 1463  Bit Score: 41.60  E-value: 7.85e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  345 RQENLLKRCKETIQSHKEQCTLltsEKEALQEQLDERLQELEK-IKDLHMAEKTklITQLrdaKNLIEQLEQDKGMVIAE 423
Cdd:COG5022   843 KAEVLIQKFGRSLKAKKRFSLL---KKETIYLQSAQRVELAERqLQELKIDVKS--ISSL---KLVNLELESEIIELKKS 914

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  424 TKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKT-EEARRKLKAEMDEQIKTIEKT 502
Cdd:COG5022   915 LSSDLIENLEFKTELIARLKKLLNNIDLEEGPSIEYVKLPELNKLHEVESKLKETSEEyEDLLKKSTILVREGNKANSEL 994

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  503 S---------EEERISLQQELSRVKQEVVDVMKKSSEEQI--------------AKLQKLHEKELARKEQELTKKLQTRE 559
Cdd:COG5022   995 KnfkkelaelSKQYGALQESTKQLKELPVEVAELQSASKIissestelsilkplQKLKGLLLLENNQLQARYKALKLRRE 1074

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  560 REFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENK 639
Cdd:COG5022  1075 NSLLDDKQLYQLESTENLLKTINVKDLEVTNRNLVKPANVLQFIVAQMIKLNLLQEISKFLSQLVNTLEPVFQKLSVLQL 1154

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  640 ---------------------NQSKDLAVHLEAEKNKhNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEME 698
Cdd:COG5022  1155 eldglfweanlealpspppfaALSEKRLYQSALYDEK-SKLSSSEVNDLKNELIALFSKIFSGWPRGDKLKKLISEGWVP 1233

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  699 KLREKCEQEKEtllkDKEIIFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMK-QELE 777
Cdd:COG5022  1234 TEYSTSLKGFN----NLNKKFDTPASMSNEKLLSLLNSIDNLLSSYKLEEEVLPATINSLLQYINVGLFNALRTKaSSLR 1309

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  778 AKMDEQKNHHQQQVDSIIKEHEVS-----------IQRTEKALKDQINQLELLLKERDKHLkehQAHVENLEADIKRSEG 846
Cdd:COG5022  1310 WKSATEVNYNSEELDDWCREFEISdvdeeleeliqAVKVLQLLKDDLNKLDELLDACYSLN---PAEIQNLKSRYDPADK 1386


                  .
gi 530372322  847 E 847
Cdd:COG5022  1387 E 1387
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 474-652 7.89e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 40.90  E-value: 7.89e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  474 ALSTAQKTEEARRKLKAEMDEQIKTIEKTsEEERISLQQELSRVKQEVVDVMKK--SSEEQIAKLQKlHEKELARKEQEL 551
Cdd:COG4942    18 QADAAAEAEAELEQLQQEIAELEKELAAL-KKEEKALLKQLAALERRIAALARRirALEQELAALEA-ELAELEKEIAEL 95

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  552 TKKLQTREREFQEQMKVALEKSQSEYLKI---------------------------------SQEKEQQESLALEELELQ 598
Cdd:COG4942    96 RAELEAQKEELAELLRALYRLGRQPPLALllspedfldavrrlqylkylaparreqaeelraDLAELAALRAELEAERAE 175

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  599 KKAILTESENKLRDLQQEAETYRTRILELESSLEK------SLQENKNQSKDLAVHLEAE 652
Cdd:COG4942   176 LEALLAELEEERAALEALKAERQKLLARLEKELAElaaelaELQQEAEELEALIARLEAE 235
SMC_prok_A TIGR02169
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ...
 1973-2199 7.99e-03

chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274009 [Multi-domain]  Cd Length: 1164  Bit Score: 41.59  E-value: 7.99e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1973 LSNMEAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKE---------HQQELEILKKEYDQEREEKIKQEQEDLEL 2043
Cdd:TIGR02169  239 KEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKikdlgeeeqLRVKEKIGELEAEIASLERSIAEKERELE 318

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  2044 KHNSTLKQLMREFNTQLAQKEqELEMTIKETINKAQEVEAELLEShQEETNQLLKKIAEKDDDLKRTakrYEEILDARE- 2122
Cdd:TIGR02169  319 DAEERLAKLEAEIDKLLAEIE-ELEREIEEERKRRDKLTEEYAEL-KEELEDLRAELEEVDKEFAET---RDELKDYREk 393

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  2123 -EEMTAKVRDLQTQLEELQKKYQQKLEQEENPGNDNTQL-AQKTTLISDSKLKEQEFREQIHNLE---DRLKKYEKNVYA 2197
Cdd:TIGR02169  394 lEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIeAKINELEEEKEDKALEIKKQEWKLEqlaADLSKYEQELYD 473


                   ..
gi 530372322  2198 TT 2199
Cdd:TIGR02169  474 LK 475
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 1489-2145 8.72e-03

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 41.26  E-value: 8.72e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1489 QVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLElksKEAYEKDEQINLLKEELDQQNKrfdcLKGEMEDDKSKMEKKE 1568
Cdd:pfam15921   86 QVKDLQRRLNESNELHEKQKFYLRQSVIDLQTKLQ---EMQMERDAMADIRRRESQSQED----LRNQLQNTVHELEAAK 158

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1569 SNLETELKSQTARIMELEDHITQKTIEIESLNEVLKNYNQ---QKDIEHKELvqKLQHFQELGEEKDNRVKEAEEKILTL 1645
Cdd:pfam15921  159 CLKEDMLEDSNTQIEQLRKMMLSHEGVLQEIRSILVDFEEasgKKIYEHDSM--STMHFRSLGSAISKILRELDTEISYL 236

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1646 ENQVYSMKAELETKKKElehvnlSVKSKEEELKALEDRLE---SESAAKLAELKRKAEQKIAAiKKQLLSQMEEKEEQYK 1722
Cdd:pfam15921  237 KGRIFPVEDQLEALKSE------SQNKIELLLQQHQDRIEqliSEHEVEITGLTEKASSARSQ-ANSIQSQLEIIQEQAR 309

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1723 KGTESHLSELNtklqererevhileeklkSVESSQSETLIVPRSAKnvaayteqeeadsqgcvqKTYEEKISVLQRNLTE 1802
Cdd:pfam15921  310 NQNSMYMRQLS------------------DLESTVSQLRSELREAK------------------RMYEDKIEELEKQLVL 353

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1803 KEKLLQRVGQEKEETVSSHFEMRCQYQ---------ERLIKLEHAEAKQHEDQSM-----IGHLQEELEEKNKKyslivA 1868
Cdd:pfam15921  354 ANSELTEARTERDQFSQESGNLDDQLQklladlhkrEKELSLEKEQNKRLWDRDTgnsitIDHLRRELDDRNME-----V 428

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1869 QHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKEltcqileqKIKELDSCLVRQKEVHRVEMEELTSKYEKLQALQQMDGR 1948
Cdd:pfam15921  429 QRLEALLKAMKSECQGQMERQMAAIQGKNESLE--------KVSSLTAQLESTKEMLRKVVEELTAKKMTLESSERTVSD 500

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  1949 NKPTELLEENTEEKSKSHLVQPKL---LSNMEAQH-NDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQELEILKK 2024
Cdd:pfam15921  501 LTASLQEKERAIEATNAEITKLRSrvdLKLQELQHlKNEGDHLRNVQTECEALKLQMAEKDKVIEILRQQIENMTQLVGQ 580

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322  2025 EYD-----QEREEKIKQEQED--LELKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEvEAELLESHQEETNQLL 2097
Cdd:pfam15921  581 HGRtagamQVEKAQLEKEINDrrLELQEFKILKDKKDAKIRELEARVSDLELEKVKLVNAGSE-RLRAVKDIKQERDQLL 659

                          650       660       670       680       690
                   ....*....|....*....|....*....|....*....|....*....|.
gi 530372322  2098 KKIAEKDDDLKRTAKRYEEI---LDAREEEMTAKVRDLQTQLEELQKKYQQ 2145
Cdd:pfam15921  660 NEVKTSRNELNSLSEDYEVLkrnFRNKSEEMETTTNKLKMQLKSAQSELEQ 710
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1629-1758 9.40e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.44  E-value: 9.40e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1629 EEKDNRVKEAEEKILTLENQVYSMK-AELETKKKELEHVNLSVKSKEEELKALEDRLES------ESAAKLAELKRKAeq 1701
Cdd:COG4913   312 ERLEARLDALREELDELEAQIRGNGgDRLEQLEREIERLERELEERERRRARLEALLAAlglplpASAEEFAALRAEA-- 389

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 530372322 1702 kiaaikKQLLSQMEEKEEQYkkgtESHLSELNTKLQEREREVHILEEKLKSVESSQS 1758
Cdd:COG4913   390 ------AALLEALEEELEAL----EEALAEAEAALRDLRRELRELEAEIASLERRKS 436
COG4913 COG4913
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
1977-2138 9.80e-03

Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];


Pssm-ID: 443941 [Multi-domain]  Cd Length: 1089  Bit Score: 41.44  E-value: 9.80e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 1977 EAQHNDLEFKLAGAEREKQKLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQEREEKIKQE-QEDLELKHNSTLKQLMRE 2055
Cdd:COG4913   698 EAELEELEEELDELKGEIGRLEKELEQAEEELDELQDRLEAAEDLARLELRALLEERFAAAlGDAVERELRENLEERIDA 777

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530372322 2056 FNTQLAQKEQELEMTIKETINKAQEVEAELLES--HQEETNQLLKKIaeKDDDLKRtakRYEEILDAREEEMTAKVRDLQ 2133
Cdd:COG4913   778 LRARLNRAEEELERAMRAFNREWPAETADLDADleSLPEYLALLDRL--EEDGLPE---YEERFKELLNENSIEFVADLL 852


                  ....*
gi 530372322 2134 TQLEE 2138
Cdd:COG4913   853 SKLRR 857
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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