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Conserved domains on  [gi|530381160|ref|XP_005266024|]
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delta-sarcoglycan isoform X3 [Homo sapiens]

Protein Classification

sarcoglycan( domain architecture ID 10521547)

sarcoglycan beta/delta/gamma/zeta is a component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Sarcoglycan_1 pfam04790
Sarcoglycan complex subunit protein; The dystrophin glycoprotein complex (DGC) is a ...
 24-168 5.76e-52

Sarcoglycan complex subunit protein; The dystrophin glycoprotein complex (DGC) is a membrane-spanning complex that links the interior cytoskeleton to the extracellular matrix in muscle. The sarcoglycan complex is a subcomplex within the DGC and is composed of several muscle-specific, transmembrane proteins (alpha-, beta-, gamma-, delta- and zeta-sarcoglycan). The sarcoglycans are asparagine-linked glycosylated proteins with single transmembrane domains. This family contains beta, gamma and delta members.


:

Pssm-ID: 461428  Cd Length: 255  Bit Score: 166.25  E-value: 5.76e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530381160   24 KVGIYGWRKRCLYFFVLLLMILILVNLAMTIWILKVMNFTIDGMGNLRITEKGLKLEGDSEFLQPLYAKEIQSRPGNALY 103
Cdd:pfam04790   1 KTGIYGWRKRCLYLLVLLLLILAVVNLALTIWILKVLRFSSNGMGSLEITPDGVRFEGESEFLDPLYAKEIHSFKDSPLS 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530381160  104 FKSARNVTVNILNDQTKVLTQLITGPK-AVEAYGKKFEVKT-VSGKLLFSADNNEVVVGAE---RLRVLG 168
Cdd:pfam04790  81 ITSDRNVVLNARNENGSVTSQLVVGPDgAVEASVNRFEVKDpDGGKTLFSADRPEVTVGADkgkKLRVTG 150
 
Name Accession Description Interval E-value
Sarcoglycan_1 pfam04790
Sarcoglycan complex subunit protein; The dystrophin glycoprotein complex (DGC) is a ...
 24-168 5.76e-52

Sarcoglycan complex subunit protein; The dystrophin glycoprotein complex (DGC) is a membrane-spanning complex that links the interior cytoskeleton to the extracellular matrix in muscle. The sarcoglycan complex is a subcomplex within the DGC and is composed of several muscle-specific, transmembrane proteins (alpha-, beta-, gamma-, delta- and zeta-sarcoglycan). The sarcoglycans are asparagine-linked glycosylated proteins with single transmembrane domains. This family contains beta, gamma and delta members.


Pssm-ID: 461428  Cd Length: 255  Bit Score: 166.25  E-value: 5.76e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530381160   24 KVGIYGWRKRCLYFFVLLLMILILVNLAMTIWILKVMNFTIDGMGNLRITEKGLKLEGDSEFLQPLYAKEIQSRPGNALY 103
Cdd:pfam04790   1 KTGIYGWRKRCLYLLVLLLLILAVVNLALTIWILKVLRFSSNGMGSLEITPDGVRFEGESEFLDPLYAKEIHSFKDSPLS 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530381160  104 FKSARNVTVNILNDQTKVLTQLITGPK-AVEAYGKKFEVKT-VSGKLLFSADNNEVVVGAE---RLRVLG 168
Cdd:pfam04790  81 ITSDRNVVLNARNENGSVTSQLVVGPDgAVEASVNRFEVKDpDGGKTLFSADRPEVTVGADkgkKLRVTG 150
 
Name Accession Description Interval E-value
Sarcoglycan_1 pfam04790
Sarcoglycan complex subunit protein; The dystrophin glycoprotein complex (DGC) is a ...
 24-168 5.76e-52

Sarcoglycan complex subunit protein; The dystrophin glycoprotein complex (DGC) is a membrane-spanning complex that links the interior cytoskeleton to the extracellular matrix in muscle. The sarcoglycan complex is a subcomplex within the DGC and is composed of several muscle-specific, transmembrane proteins (alpha-, beta-, gamma-, delta- and zeta-sarcoglycan). The sarcoglycans are asparagine-linked glycosylated proteins with single transmembrane domains. This family contains beta, gamma and delta members.


Pssm-ID: 461428  Cd Length: 255  Bit Score: 166.25  E-value: 5.76e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530381160   24 KVGIYGWRKRCLYFFVLLLMILILVNLAMTIWILKVMNFTIDGMGNLRITEKGLKLEGDSEFLQPLYAKEIQSRPGNALY 103
Cdd:pfam04790   1 KTGIYGWRKRCLYLLVLLLLILAVVNLALTIWILKVLRFSSNGMGSLEITPDGVRFEGESEFLDPLYAKEIHSFKDSPLS 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530381160  104 FKSARNVTVNILNDQTKVLTQLITGPK-AVEAYGKKFEVKT-VSGKLLFSADNNEVVVGAE---RLRVLG 168
Cdd:pfam04790  81 ITSDRNVVLNARNENGSVTSQLVVGPDgAVEASVNRFEVKDpDGGKTLFSADRPEVTVGADkgkKLRVTG 150
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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