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Conserved domains on  [gi|530402968|ref|XP_005267329|]
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exocyst complex component 5 isoform X1 [Homo sapiens]

Protein Classification

exocyst complex component Sec10( domain architecture ID 10538384)

exocyst complex component Sec10 is a component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Sec10 pfam07393
Exocyst complex component Sec10; This family contains the Sec10 component (approximately 650 ...
127-745 0e+00

Exocyst complex component Sec10; This family contains the Sec10 component (approximately 650 residues long) of the eukaryotic exocyst complex, which specifically affects the synthesis and delivery of secretory and basolateral plasma membrane proteins.


:

Pssm-ID: 399988  Cd Length: 704  Bit Score: 570.83  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530402968  127 NQVAFQHFQELDEHISYVATKVCHLGDQLEGVNTPRQRAVEAQKLMKYFNEFLDG------ELKSDVFTNSEKIKEAADI 200
Cdd:pfam07393   1 LQETVDSFDQLDDKISSVGQKAVKLGDQLEGADRQRQRAIDAAFLIPFYDEFLSSgpssplELLFKRSKDPDKKLECAQI 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530402968  201 IQKLHLIAQEL-PFDRFSEVKSKIASKYHDLECQLIQEFTSAQRRGEISRMREVAAVLLHFKGYSHCVDVYIKQCQEGA- 278
Cdd:pfam07393  81 ARQLLSIAQKLdPLPKTENTRANIEKYSERLEKELLKEFDAAYRKEDFERMKECAKILQEFNGGASVIQLFVNQHQFFId 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530402968  279 -----------------------------YLRNDIFEDAGILCQRVNKQVGDIFSNPETVLAKLIQNVFEIKLQSFVKEQ 329
Cdd:pfam07393 161 rdvtdevdglddeiwekladpdqhpsiveESLQALFSEVVVVVKEEAAIIKRVFPNPEVVMQKFIQRVFAQVIQQRLEAL 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530402968  330 LEECRKSDAEQYLKNLYDLYTRTTNLSSKLMEF--NLGTDKQTFLSKLIKSIFISYLENYIEVETGYLKSRSAMILQRYY 407
Cdd:pfam07393 241 LDKAKSISQLAYLRSLHSLYSQTLKLVKDLKEFgsTENPDLSAFLDQLTEDLFVPHLDSYLEREKKSLEELYESLLSKFT 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530402968  408 -----------------------------DSKNHQKRSIG--TGGIQDLKERIRQRTNL----------PLGPSIDTHGE 446
Cdd:pfam07393 321 tlheraisaksltnkdkkdfltsfkaslmGSKLASKSKLSqiNRFLKSSLERTLKRAGLfenidssakaAINPIELEGID 400
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530402968  447 TFLSQEVVVNLLQETKQAFERCHRLSDPSDLPRNAFRIFTILVEFLCIEHIDYALETGLAGIPSSDSR----NANLYFLD 522
Cdd:pfam07393 401 SLLSIEVALSMLKWAAESLGRALELSSPTELPKNIEALFDLLLRALGHEYIETALEAALYALSSQEIAektgVPDLSFLE 480
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530402968  523 VVQQANTIFHLFDKQFNDHLMPLISSSPK-LSECLQKKKEIIEQMEMKLDTGIDRTLNCMIGQMKHILAaEQKKTDFKPE 601
Cdd:pfam07393 481 VVRVCDEILSLMSVYIKQILIPLLTNSPDiRREMVKKKNSFISRLEEKVNAGLQKTIDVLMGWVKYILS-KQKKTDFRPK 559
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530402968  602 DENNVL-IQYTNACVKVCAYVRKQVEKIKNSMDGKNVDTVLMELGVRFHRLIYEHLQQYSYSCMGGMLAICDVAEYRKCA 680
Cdd:pfam07393 560 EDELTMdVQPTEACQEVVDFLSSVHSQLVGSLDGSNLEAFLTEIGLRLHRLLLEHLKKFTVNSEGGLILTKDINEYQKFV 639
                         650       660       670       680       690       700
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 530402968  681 KDFKIPMVLHLFDTLHALCNLLVVAPDNLKQVCSGEQLANLDKNILHSFVQLRADYRSARLARHF 745
Cdd:pfam07393 640 KSWGIPELLEKFELLRELGNLFIVQPDLLKELVTEGALANLDRELIREYIQLREDYNQIKLDVEL 704
 
Name Accession Description Interval E-value
Sec10 pfam07393
Exocyst complex component Sec10; This family contains the Sec10 component (approximately 650 ...
127-745 0e+00

Exocyst complex component Sec10; This family contains the Sec10 component (approximately 650 residues long) of the eukaryotic exocyst complex, which specifically affects the synthesis and delivery of secretory and basolateral plasma membrane proteins.


Pssm-ID: 399988  Cd Length: 704  Bit Score: 570.83  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530402968  127 NQVAFQHFQELDEHISYVATKVCHLGDQLEGVNTPRQRAVEAQKLMKYFNEFLDG------ELKSDVFTNSEKIKEAADI 200
Cdd:pfam07393   1 LQETVDSFDQLDDKISSVGQKAVKLGDQLEGADRQRQRAIDAAFLIPFYDEFLSSgpssplELLFKRSKDPDKKLECAQI 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530402968  201 IQKLHLIAQEL-PFDRFSEVKSKIASKYHDLECQLIQEFTSAQRRGEISRMREVAAVLLHFKGYSHCVDVYIKQCQEGA- 278
Cdd:pfam07393  81 ARQLLSIAQKLdPLPKTENTRANIEKYSERLEKELLKEFDAAYRKEDFERMKECAKILQEFNGGASVIQLFVNQHQFFId 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530402968  279 -----------------------------YLRNDIFEDAGILCQRVNKQVGDIFSNPETVLAKLIQNVFEIKLQSFVKEQ 329
Cdd:pfam07393 161 rdvtdevdglddeiwekladpdqhpsiveESLQALFSEVVVVVKEEAAIIKRVFPNPEVVMQKFIQRVFAQVIQQRLEAL 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530402968  330 LEECRKSDAEQYLKNLYDLYTRTTNLSSKLMEF--NLGTDKQTFLSKLIKSIFISYLENYIEVETGYLKSRSAMILQRYY 407
Cdd:pfam07393 241 LDKAKSISQLAYLRSLHSLYSQTLKLVKDLKEFgsTENPDLSAFLDQLTEDLFVPHLDSYLEREKKSLEELYESLLSKFT 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530402968  408 -----------------------------DSKNHQKRSIG--TGGIQDLKERIRQRTNL----------PLGPSIDTHGE 446
Cdd:pfam07393 321 tlheraisaksltnkdkkdfltsfkaslmGSKLASKSKLSqiNRFLKSSLERTLKRAGLfenidssakaAINPIELEGID 400
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530402968  447 TFLSQEVVVNLLQETKQAFERCHRLSDPSDLPRNAFRIFTILVEFLCIEHIDYALETGLAGIPSSDSR----NANLYFLD 522
Cdd:pfam07393 401 SLLSIEVALSMLKWAAESLGRALELSSPTELPKNIEALFDLLLRALGHEYIETALEAALYALSSQEIAektgVPDLSFLE 480
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530402968  523 VVQQANTIFHLFDKQFNDHLMPLISSSPK-LSECLQKKKEIIEQMEMKLDTGIDRTLNCMIGQMKHILAaEQKKTDFKPE 601
Cdd:pfam07393 481 VVRVCDEILSLMSVYIKQILIPLLTNSPDiRREMVKKKNSFISRLEEKVNAGLQKTIDVLMGWVKYILS-KQKKTDFRPK 559
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530402968  602 DENNVL-IQYTNACVKVCAYVRKQVEKIKNSMDGKNVDTVLMELGVRFHRLIYEHLQQYSYSCMGGMLAICDVAEYRKCA 680
Cdd:pfam07393 560 EDELTMdVQPTEACQEVVDFLSSVHSQLVGSLDGSNLEAFLTEIGLRLHRLLLEHLKKFTVNSEGGLILTKDINEYQKFV 639
                         650       660       670       680       690       700
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 530402968  681 KDFKIPMVLHLFDTLHALCNLLVVAPDNLKQVCSGEQLANLDKNILHSFVQLRADYRSARLARHF 745
Cdd:pfam07393 640 KSWGIPELLEKFELLRELGNLFIVQPDLLKELVTEGALANLDRELIREYIQLREDYNQIKLDVEL 704
PTZ00332 PTZ00332
paraflagellar rod protein; Provisional
87-223 5.26e-03

paraflagellar rod protein; Provisional


Pssm-ID: 240364 [Multi-domain]  Cd Length: 589  Bit Score: 39.95  E-value: 5.26e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530402968  87 HIQELQIMDERIQRKVEKLEQ-------------QCQKEAKEFaKKVQELQKsnqvafQHFQELDEHISYVATKVCHLGD 153
Cdd:PTZ00332 206 HDGEMQVAEEQMWTKVQLQERlielvadkfrligKCEEENKSF-SKIHEVQK------QANQETSQMKDAKRRLKQRCET 278
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 530402968 154 QLEGVNTPRQRA-VEAQKLMKyfnEFLDGELKSDVFT--NSEKIKEAADIIQKLHLIAQELPFDRFSEVKSKI 223
Cdd:PTZ00332 279 DLKHIHDAIQKAdLEDAEAMK---RYATNKEKSERFIreNEDRQEEAWNKIQDLERQLQRLGTERFEEVKRRI 348
 
Name Accession Description Interval E-value
Sec10 pfam07393
Exocyst complex component Sec10; This family contains the Sec10 component (approximately 650 ...
127-745 0e+00

Exocyst complex component Sec10; This family contains the Sec10 component (approximately 650 residues long) of the eukaryotic exocyst complex, which specifically affects the synthesis and delivery of secretory and basolateral plasma membrane proteins.


Pssm-ID: 399988  Cd Length: 704  Bit Score: 570.83  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530402968  127 NQVAFQHFQELDEHISYVATKVCHLGDQLEGVNTPRQRAVEAQKLMKYFNEFLDG------ELKSDVFTNSEKIKEAADI 200
Cdd:pfam07393   1 LQETVDSFDQLDDKISSVGQKAVKLGDQLEGADRQRQRAIDAAFLIPFYDEFLSSgpssplELLFKRSKDPDKKLECAQI 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530402968  201 IQKLHLIAQEL-PFDRFSEVKSKIASKYHDLECQLIQEFTSAQRRGEISRMREVAAVLLHFKGYSHCVDVYIKQCQEGA- 278
Cdd:pfam07393  81 ARQLLSIAQKLdPLPKTENTRANIEKYSERLEKELLKEFDAAYRKEDFERMKECAKILQEFNGGASVIQLFVNQHQFFId 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530402968  279 -----------------------------YLRNDIFEDAGILCQRVNKQVGDIFSNPETVLAKLIQNVFEIKLQSFVKEQ 329
Cdd:pfam07393 161 rdvtdevdglddeiwekladpdqhpsiveESLQALFSEVVVVVKEEAAIIKRVFPNPEVVMQKFIQRVFAQVIQQRLEAL 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530402968  330 LEECRKSDAEQYLKNLYDLYTRTTNLSSKLMEF--NLGTDKQTFLSKLIKSIFISYLENYIEVETGYLKSRSAMILQRYY 407
Cdd:pfam07393 241 LDKAKSISQLAYLRSLHSLYSQTLKLVKDLKEFgsTENPDLSAFLDQLTEDLFVPHLDSYLEREKKSLEELYESLLSKFT 320
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530402968  408 -----------------------------DSKNHQKRSIG--TGGIQDLKERIRQRTNL----------PLGPSIDTHGE 446
Cdd:pfam07393 321 tlheraisaksltnkdkkdfltsfkaslmGSKLASKSKLSqiNRFLKSSLERTLKRAGLfenidssakaAINPIELEGID 400
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530402968  447 TFLSQEVVVNLLQETKQAFERCHRLSDPSDLPRNAFRIFTILVEFLCIEHIDYALETGLAGIPSSDSR----NANLYFLD 522
Cdd:pfam07393 401 SLLSIEVALSMLKWAAESLGRALELSSPTELPKNIEALFDLLLRALGHEYIETALEAALYALSSQEIAektgVPDLSFLE 480
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530402968  523 VVQQANTIFHLFDKQFNDHLMPLISSSPK-LSECLQKKKEIIEQMEMKLDTGIDRTLNCMIGQMKHILAaEQKKTDFKPE 601
Cdd:pfam07393 481 VVRVCDEILSLMSVYIKQILIPLLTNSPDiRREMVKKKNSFISRLEEKVNAGLQKTIDVLMGWVKYILS-KQKKTDFRPK 559
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530402968  602 DENNVL-IQYTNACVKVCAYVRKQVEKIKNSMDGKNVDTVLMELGVRFHRLIYEHLQQYSYSCMGGMLAICDVAEYRKCA 680
Cdd:pfam07393 560 EDELTMdVQPTEACQEVVDFLSSVHSQLVGSLDGSNLEAFLTEIGLRLHRLLLEHLKKFTVNSEGGLILTKDINEYQKFV 639
                         650       660       670       680       690       700
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 530402968  681 KDFKIPMVLHLFDTLHALCNLLVVAPDNLKQVCSGEQLANLDKNILHSFVQLRADYRSARLARHF 745
Cdd:pfam07393 640 KSWGIPELLEKFELLRELGNLFIVQPDLLKELVTEGALANLDRELIREYIQLREDYNQIKLDVEL 704
PTZ00332 PTZ00332
paraflagellar rod protein; Provisional
87-223 5.26e-03

paraflagellar rod protein; Provisional


Pssm-ID: 240364 [Multi-domain]  Cd Length: 589  Bit Score: 39.95  E-value: 5.26e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 530402968  87 HIQELQIMDERIQRKVEKLEQ-------------QCQKEAKEFaKKVQELQKsnqvafQHFQELDEHISYVATKVCHLGD 153
Cdd:PTZ00332 206 HDGEMQVAEEQMWTKVQLQERlielvadkfrligKCEEENKSF-SKIHEVQK------QANQETSQMKDAKRRLKQRCET 278
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 530402968 154 QLEGVNTPRQRA-VEAQKLMKyfnEFLDGELKSDVFT--NSEKIKEAADIIQKLHLIAQELPFDRFSEVKSKI 223
Cdd:PTZ00332 279 DLKHIHDAIQKAdLEDAEAMK---RYATNKEKSERFIreNEDRQEEAWNKIQDLERQLQRLGTERFEEVKRRI 348
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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