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latent-transforming growth factor beta-binding protein 2 isoform X1 [Rattus norvegicus]
List of domain hits
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Name | Accession | Description | Interval | E-value | |||
TB | pfam00683 | TB domain; This domain is also known as the 8 cysteine domain. This family includes the hybrid ... |
687-730 | 1.92e-13 | |||
TB domain; This domain is also known as the 8 cysteine domain. This family includes the hybrid domains. This cysteine rich repeat is found in TGF binding protein and fibrillin. : Pssm-ID: 459903 Cd Length: 44 Bit Score: 66.15 E-value: 1.92e-13
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TB | pfam00683 | TB domain; This domain is also known as the 8 cysteine domain. This family includes the hybrid ... |
1433-1473 | 1.10e-08 | |||
TB domain; This domain is also known as the 8 cysteine domain. This family includes the hybrid domains. This cysteine rich repeat is found in TGF binding protein and fibrillin. : Pssm-ID: 459903 Cd Length: 44 Bit Score: 52.67 E-value: 1.10e-08
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TB | pfam00683 | TB domain; This domain is also known as the 8 cysteine domain. This family includes the hybrid ... |
1603-1646 | 2.34e-07 | |||
TB domain; This domain is also known as the 8 cysteine domain. This family includes the hybrid domains. This cysteine rich repeat is found in TGF binding protein and fibrillin. : Pssm-ID: 459903 Cd Length: 44 Bit Score: 48.81 E-value: 2.34e-07
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EGF_CA | smart00179 | Calcium-binding EGF-like domain; |
1313-1346 | 3.25e-07 | |||
Calcium-binding EGF-like domain; : Pssm-ID: 214542 [Multi-domain] Cd Length: 39 Bit Score: 48.40 E-value: 3.25e-07
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EGF_CA | smart00179 | Calcium-binding EGF-like domain; |
940-970 | 2.78e-06 | |||
Calcium-binding EGF-like domain; : Pssm-ID: 214542 [Multi-domain] Cd Length: 39 Bit Score: 45.70 E-value: 2.78e-06
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EGF_CA | pfam07645 | Calcium-binding EGF domain; |
1145-1175 | 2.84e-06 | |||
Calcium-binding EGF domain; : Pssm-ID: 429571 Cd Length: 32 Bit Score: 45.31 E-value: 2.84e-06
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EGF_CA | smart00179 | Calcium-binding EGF-like domain; |
1020-1051 | 4.82e-06 | |||
Calcium-binding EGF-like domain; : Pssm-ID: 214542 [Multi-domain] Cd Length: 39 Bit Score: 44.93 E-value: 4.82e-06
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EGF_CA | smart00179 | Calcium-binding EGF-like domain; |
1186-1227 | 5.75e-06 | |||
Calcium-binding EGF-like domain; : Pssm-ID: 214542 [Multi-domain] Cd Length: 39 Bit Score: 44.55 E-value: 5.75e-06
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EGF_CA | smart00179 | Calcium-binding EGF-like domain; |
1228-1259 | 8.34e-06 | |||
Calcium-binding EGF-like domain; : Pssm-ID: 214542 [Multi-domain] Cd Length: 39 Bit Score: 44.16 E-value: 8.34e-06
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EGF_CA | cd00054 | Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ... |
897-931 | 1.86e-05 | |||
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements. : Pssm-ID: 238011 Cd Length: 38 Bit Score: 43.39 E-value: 1.86e-05
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EGF_CA | smart00179 | Calcium-binding EGF-like domain; |
1784-1818 | 5.60e-05 | |||
Calcium-binding EGF-like domain; : Pssm-ID: 214542 [Multi-domain] Cd Length: 39 Bit Score: 41.85 E-value: 5.60e-05
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EGF_CA | smart00179 | Calcium-binding EGF-like domain; |
628-657 | 2.17e-04 | |||
Calcium-binding EGF-like domain; : Pssm-ID: 214542 [Multi-domain] Cd Length: 39 Bit Score: 40.31 E-value: 2.17e-04
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EGF_CA | cd00054 | Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ... |
980-1015 | 3.57e-04 | |||
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements. : Pssm-ID: 238011 Cd Length: 38 Bit Score: 39.54 E-value: 3.57e-04
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EGF_CA | pfam07645 | Calcium-binding EGF domain; |
1103-1133 | 5.11e-04 | |||
Calcium-binding EGF domain; : Pssm-ID: 429571 Cd Length: 32 Bit Score: 39.14 E-value: 5.11e-04
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EGF_CA | smart00179 | Calcium-binding EGF-like domain; |
1061-1102 | 7.73e-04 | |||
Calcium-binding EGF-like domain; : Pssm-ID: 214542 [Multi-domain] Cd Length: 39 Bit Score: 38.77 E-value: 7.73e-04
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PHA03378 super family | cl33729 | EBNA-3B; Provisional |
756-854 | 1.89e-03 | |||
EBNA-3B; Provisional The actual alignment was detected with superfamily member PHA03378: Pssm-ID: 223065 [Multi-domain] Cd Length: 991 Bit Score: 43.13 E-value: 1.89e-03
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EGF_CA | smart00179 | Calcium-binding EGF-like domain; |
1495-1528 | 2.20e-03 | |||
Calcium-binding EGF-like domain; : Pssm-ID: 214542 [Multi-domain] Cd Length: 39 Bit Score: 37.23 E-value: 2.20e-03
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TB | pfam00683 | TB domain; This domain is also known as the 8 cysteine domain. This family includes the hybrid ... |
567-601 | 8.20e-03 | |||
TB domain; This domain is also known as the 8 cysteine domain. This family includes the hybrid domains. This cysteine rich repeat is found in TGF binding protein and fibrillin. : Pssm-ID: 459903 Cd Length: 44 Bit Score: 36.10 E-value: 8.20e-03
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Name | Accession | Description | Interval | E-value | |||
TB | pfam00683 | TB domain; This domain is also known as the 8 cysteine domain. This family includes the hybrid ... |
687-730 | 1.92e-13 | |||
TB domain; This domain is also known as the 8 cysteine domain. This family includes the hybrid domains. This cysteine rich repeat is found in TGF binding protein and fibrillin. Pssm-ID: 459903 Cd Length: 44 Bit Score: 66.15 E-value: 1.92e-13
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TB | pfam00683 | TB domain; This domain is also known as the 8 cysteine domain. This family includes the hybrid ... |
1433-1473 | 1.10e-08 | |||
TB domain; This domain is also known as the 8 cysteine domain. This family includes the hybrid domains. This cysteine rich repeat is found in TGF binding protein and fibrillin. Pssm-ID: 459903 Cd Length: 44 Bit Score: 52.67 E-value: 1.10e-08
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TB | pfam00683 | TB domain; This domain is also known as the 8 cysteine domain. This family includes the hybrid ... |
1603-1646 | 2.34e-07 | |||
TB domain; This domain is also known as the 8 cysteine domain. This family includes the hybrid domains. This cysteine rich repeat is found in TGF binding protein and fibrillin. Pssm-ID: 459903 Cd Length: 44 Bit Score: 48.81 E-value: 2.34e-07
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EGF_CA | smart00179 | Calcium-binding EGF-like domain; |
1313-1346 | 3.25e-07 | |||
Calcium-binding EGF-like domain; Pssm-ID: 214542 [Multi-domain] Cd Length: 39 Bit Score: 48.40 E-value: 3.25e-07
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EGF_CA | cd00054 | Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ... |
1313-1345 | 4.33e-07 | |||
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements. Pssm-ID: 238011 Cd Length: 38 Bit Score: 48.02 E-value: 4.33e-07
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EGF_CA | smart00179 | Calcium-binding EGF-like domain; |
940-970 | 2.78e-06 | |||
Calcium-binding EGF-like domain; Pssm-ID: 214542 [Multi-domain] Cd Length: 39 Bit Score: 45.70 E-value: 2.78e-06
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EGF_CA | pfam07645 | Calcium-binding EGF domain; |
1145-1175 | 2.84e-06 | |||
Calcium-binding EGF domain; Pssm-ID: 429571 Cd Length: 32 Bit Score: 45.31 E-value: 2.84e-06
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EGF_CA | smart00179 | Calcium-binding EGF-like domain; |
1020-1051 | 4.82e-06 | |||
Calcium-binding EGF-like domain; Pssm-ID: 214542 [Multi-domain] Cd Length: 39 Bit Score: 44.93 E-value: 4.82e-06
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EGF_CA | smart00179 | Calcium-binding EGF-like domain; |
1186-1227 | 5.75e-06 | |||
Calcium-binding EGF-like domain; Pssm-ID: 214542 [Multi-domain] Cd Length: 39 Bit Score: 44.55 E-value: 5.75e-06
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EGF_CA | cd00054 | Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ... |
940-970 | 6.56e-06 | |||
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements. Pssm-ID: 238011 Cd Length: 38 Bit Score: 44.55 E-value: 6.56e-06
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EGF_CA | smart00179 | Calcium-binding EGF-like domain; |
1228-1259 | 8.34e-06 | |||
Calcium-binding EGF-like domain; Pssm-ID: 214542 [Multi-domain] Cd Length: 39 Bit Score: 44.16 E-value: 8.34e-06
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EGF_CA | smart00179 | Calcium-binding EGF-like domain; |
1145-1185 | 1.71e-05 | |||
Calcium-binding EGF-like domain; Pssm-ID: 214542 [Multi-domain] Cd Length: 39 Bit Score: 43.39 E-value: 1.71e-05
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EGF_CA | cd00054 | Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ... |
897-931 | 1.86e-05 | |||
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements. Pssm-ID: 238011 Cd Length: 38 Bit Score: 43.39 E-value: 1.86e-05
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EGF_CA | cd00054 | Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ... |
1020-1053 | 1.95e-05 | |||
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements. Pssm-ID: 238011 Cd Length: 38 Bit Score: 43.01 E-value: 1.95e-05
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EGF_CA | cd00054 | Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ... |
1228-1259 | 3.12e-05 | |||
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements. Pssm-ID: 238011 Cd Length: 38 Bit Score: 42.62 E-value: 3.12e-05
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EGF_CA | cd00054 | Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ... |
1186-1227 | 3.99e-05 | |||
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements. Pssm-ID: 238011 Cd Length: 38 Bit Score: 42.24 E-value: 3.99e-05
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EGF_CA | smart00179 | Calcium-binding EGF-like domain; |
897-928 | 4.26e-05 | |||
Calcium-binding EGF-like domain; Pssm-ID: 214542 [Multi-domain] Cd Length: 39 Bit Score: 42.23 E-value: 4.26e-05
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EGF_CA | smart00179 | Calcium-binding EGF-like domain; |
1784-1818 | 5.60e-05 | |||
Calcium-binding EGF-like domain; Pssm-ID: 214542 [Multi-domain] Cd Length: 39 Bit Score: 41.85 E-value: 5.60e-05
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EGF_CA | cd00054 | Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ... |
1145-1180 | 8.84e-05 | |||
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements. Pssm-ID: 238011 Cd Length: 38 Bit Score: 41.47 E-value: 8.84e-05
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EGF_CA | smart00179 | Calcium-binding EGF-like domain; |
628-657 | 2.17e-04 | |||
Calcium-binding EGF-like domain; Pssm-ID: 214542 [Multi-domain] Cd Length: 39 Bit Score: 40.31 E-value: 2.17e-04
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EGF_CA | pfam07645 | Calcium-binding EGF domain; |
1313-1343 | 2.49e-04 | |||
Calcium-binding EGF domain; Pssm-ID: 429571 Cd Length: 32 Bit Score: 39.91 E-value: 2.49e-04
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EGF_CA | pfam07645 | Calcium-binding EGF domain; |
1228-1257 | 2.54e-04 | |||
Calcium-binding EGF domain; Pssm-ID: 429571 Cd Length: 32 Bit Score: 39.91 E-value: 2.54e-04
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EGF_CA | cd00054 | Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ... |
980-1015 | 3.57e-04 | |||
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements. Pssm-ID: 238011 Cd Length: 38 Bit Score: 39.54 E-value: 3.57e-04
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EGF_CA | pfam07645 | Calcium-binding EGF domain; |
1103-1133 | 5.11e-04 | |||
Calcium-binding EGF domain; Pssm-ID: 429571 Cd Length: 32 Bit Score: 39.14 E-value: 5.11e-04
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EGF_CA | cd00054 | Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ... |
628-661 | 5.56e-04 | |||
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements. Pssm-ID: 238011 Cd Length: 38 Bit Score: 39.16 E-value: 5.56e-04
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EGF_CA | cd00054 | Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ... |
1784-1818 | 7.61e-04 | |||
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements. Pssm-ID: 238011 Cd Length: 38 Bit Score: 38.77 E-value: 7.61e-04
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EGF_CA | smart00179 | Calcium-binding EGF-like domain; |
1061-1102 | 7.73e-04 | |||
Calcium-binding EGF-like domain; Pssm-ID: 214542 [Multi-domain] Cd Length: 39 Bit Score: 38.77 E-value: 7.73e-04
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EGF_CA | pfam07645 | Calcium-binding EGF domain; |
940-969 | 1.30e-03 | |||
Calcium-binding EGF domain; Pssm-ID: 429571 Cd Length: 32 Bit Score: 37.99 E-value: 1.30e-03
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EGF_CA | pfam07645 | Calcium-binding EGF domain; |
1784-1817 | 1.69e-03 | |||
Calcium-binding EGF domain; Pssm-ID: 429571 Cd Length: 32 Bit Score: 37.60 E-value: 1.69e-03
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PHA03378 | PHA03378 | EBNA-3B; Provisional |
756-854 | 1.89e-03 | |||
EBNA-3B; Provisional Pssm-ID: 223065 [Multi-domain] Cd Length: 991 Bit Score: 43.13 E-value: 1.89e-03
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EGF_CA | smart00179 | Calcium-binding EGF-like domain; |
1495-1528 | 2.20e-03 | |||
Calcium-binding EGF-like domain; Pssm-ID: 214542 [Multi-domain] Cd Length: 39 Bit Score: 37.23 E-value: 2.20e-03
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EGF_CA | smart00179 | Calcium-binding EGF-like domain; |
1103-1144 | 2.65e-03 | |||
Calcium-binding EGF-like domain; Pssm-ID: 214542 [Multi-domain] Cd Length: 39 Bit Score: 37.23 E-value: 2.65e-03
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EGF_CA | smart00179 | Calcium-binding EGF-like domain; |
980-1011 | 3.01e-03 | |||
Calcium-binding EGF-like domain; Pssm-ID: 214542 [Multi-domain] Cd Length: 39 Bit Score: 36.84 E-value: 3.01e-03
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EGF | pfam00008 | EGF-like domain; There is no clear separation between noise and signal. pfam00053 is very ... |
901-928 | 4.48e-03 | |||
EGF-like domain; There is no clear separation between noise and signal. pfam00053 is very similar, but has 8 instead of 6 conserved cysteines. Includes some cytokine receptors. The EGF domain misses the N-terminus regions of the Ca2+ binding EGF domains (this is the main reason of discrepancy between swiss-prot domain start/end and Pfam). The family is hard to model due to many similar but different sub-types of EGF domains. Pfam certainly misses a number of EGF domains. Pssm-ID: 394967 Cd Length: 31 Bit Score: 36.21 E-value: 4.48e-03
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EGF_CA | cd00054 | Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ... |
1103-1144 | 6.20e-03 | |||
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements. Pssm-ID: 238011 Cd Length: 38 Bit Score: 36.08 E-value: 6.20e-03
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TB | pfam00683 | TB domain; This domain is also known as the 8 cysteine domain. This family includes the hybrid ... |
567-601 | 8.20e-03 | |||
TB domain; This domain is also known as the 8 cysteine domain. This family includes the hybrid domains. This cysteine rich repeat is found in TGF binding protein and fibrillin. Pssm-ID: 459903 Cd Length: 44 Bit Score: 36.10 E-value: 8.20e-03
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Name | Accession | Description | Interval | E-value | |||
TB | pfam00683 | TB domain; This domain is also known as the 8 cysteine domain. This family includes the hybrid ... |
687-730 | 1.92e-13 | |||
TB domain; This domain is also known as the 8 cysteine domain. This family includes the hybrid domains. This cysteine rich repeat is found in TGF binding protein and fibrillin. Pssm-ID: 459903 Cd Length: 44 Bit Score: 66.15 E-value: 1.92e-13
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TB | pfam00683 | TB domain; This domain is also known as the 8 cysteine domain. This family includes the hybrid ... |
1433-1473 | 1.10e-08 | |||
TB domain; This domain is also known as the 8 cysteine domain. This family includes the hybrid domains. This cysteine rich repeat is found in TGF binding protein and fibrillin. Pssm-ID: 459903 Cd Length: 44 Bit Score: 52.67 E-value: 1.10e-08
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TB | pfam00683 | TB domain; This domain is also known as the 8 cysteine domain. This family includes the hybrid ... |
1603-1646 | 2.34e-07 | |||
TB domain; This domain is also known as the 8 cysteine domain. This family includes the hybrid domains. This cysteine rich repeat is found in TGF binding protein and fibrillin. Pssm-ID: 459903 Cd Length: 44 Bit Score: 48.81 E-value: 2.34e-07
|
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EGF_CA | smart00179 | Calcium-binding EGF-like domain; |
1313-1346 | 3.25e-07 | |||
Calcium-binding EGF-like domain; Pssm-ID: 214542 [Multi-domain] Cd Length: 39 Bit Score: 48.40 E-value: 3.25e-07
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EGF_CA | cd00054 | Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ... |
1313-1345 | 4.33e-07 | |||
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements. Pssm-ID: 238011 Cd Length: 38 Bit Score: 48.02 E-value: 4.33e-07
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EGF_CA | smart00179 | Calcium-binding EGF-like domain; |
940-970 | 2.78e-06 | |||
Calcium-binding EGF-like domain; Pssm-ID: 214542 [Multi-domain] Cd Length: 39 Bit Score: 45.70 E-value: 2.78e-06
|
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EGF_CA | pfam07645 | Calcium-binding EGF domain; |
1145-1175 | 2.84e-06 | |||
Calcium-binding EGF domain; Pssm-ID: 429571 Cd Length: 32 Bit Score: 45.31 E-value: 2.84e-06
|
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EGF_CA | smart00179 | Calcium-binding EGF-like domain; |
1020-1051 | 4.82e-06 | |||
Calcium-binding EGF-like domain; Pssm-ID: 214542 [Multi-domain] Cd Length: 39 Bit Score: 44.93 E-value: 4.82e-06
|
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EGF_CA | smart00179 | Calcium-binding EGF-like domain; |
1186-1227 | 5.75e-06 | |||
Calcium-binding EGF-like domain; Pssm-ID: 214542 [Multi-domain] Cd Length: 39 Bit Score: 44.55 E-value: 5.75e-06
|
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EGF_CA | cd00054 | Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ... |
940-970 | 6.56e-06 | |||
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements. Pssm-ID: 238011 Cd Length: 38 Bit Score: 44.55 E-value: 6.56e-06
|
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EGF_CA | smart00179 | Calcium-binding EGF-like domain; |
1228-1259 | 8.34e-06 | |||
Calcium-binding EGF-like domain; Pssm-ID: 214542 [Multi-domain] Cd Length: 39 Bit Score: 44.16 E-value: 8.34e-06
|
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EGF_CA | smart00179 | Calcium-binding EGF-like domain; |
1145-1185 | 1.71e-05 | |||
Calcium-binding EGF-like domain; Pssm-ID: 214542 [Multi-domain] Cd Length: 39 Bit Score: 43.39 E-value: 1.71e-05
|
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EGF_CA | cd00054 | Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ... |
897-931 | 1.86e-05 | |||
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements. Pssm-ID: 238011 Cd Length: 38 Bit Score: 43.39 E-value: 1.86e-05
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EGF_CA | cd00054 | Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ... |
1020-1053 | 1.95e-05 | |||
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements. Pssm-ID: 238011 Cd Length: 38 Bit Score: 43.01 E-value: 1.95e-05
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EGF_CA | cd00054 | Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ... |
1228-1259 | 3.12e-05 | |||
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements. Pssm-ID: 238011 Cd Length: 38 Bit Score: 42.62 E-value: 3.12e-05
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EGF_CA | cd00054 | Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ... |
1186-1227 | 3.99e-05 | |||
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements. Pssm-ID: 238011 Cd Length: 38 Bit Score: 42.24 E-value: 3.99e-05
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EGF_CA | smart00179 | Calcium-binding EGF-like domain; |
897-928 | 4.26e-05 | |||
Calcium-binding EGF-like domain; Pssm-ID: 214542 [Multi-domain] Cd Length: 39 Bit Score: 42.23 E-value: 4.26e-05
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EGF_CA | smart00179 | Calcium-binding EGF-like domain; |
1784-1818 | 5.60e-05 | |||
Calcium-binding EGF-like domain; Pssm-ID: 214542 [Multi-domain] Cd Length: 39 Bit Score: 41.85 E-value: 5.60e-05
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EGF_CA | cd00054 | Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ... |
1145-1180 | 8.84e-05 | |||
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements. Pssm-ID: 238011 Cd Length: 38 Bit Score: 41.47 E-value: 8.84e-05
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EGF_CA | smart00179 | Calcium-binding EGF-like domain; |
628-657 | 2.17e-04 | |||
Calcium-binding EGF-like domain; Pssm-ID: 214542 [Multi-domain] Cd Length: 39 Bit Score: 40.31 E-value: 2.17e-04
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EGF_CA | pfam07645 | Calcium-binding EGF domain; |
1313-1343 | 2.49e-04 | |||
Calcium-binding EGF domain; Pssm-ID: 429571 Cd Length: 32 Bit Score: 39.91 E-value: 2.49e-04
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EGF_CA | pfam07645 | Calcium-binding EGF domain; |
1228-1257 | 2.54e-04 | |||
Calcium-binding EGF domain; Pssm-ID: 429571 Cd Length: 32 Bit Score: 39.91 E-value: 2.54e-04
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EGF_CA | cd00054 | Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ... |
980-1015 | 3.57e-04 | |||
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements. Pssm-ID: 238011 Cd Length: 38 Bit Score: 39.54 E-value: 3.57e-04
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EGF_CA | pfam07645 | Calcium-binding EGF domain; |
1103-1133 | 5.11e-04 | |||
Calcium-binding EGF domain; Pssm-ID: 429571 Cd Length: 32 Bit Score: 39.14 E-value: 5.11e-04
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EGF_CA | cd00054 | Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ... |
628-661 | 5.56e-04 | |||
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements. Pssm-ID: 238011 Cd Length: 38 Bit Score: 39.16 E-value: 5.56e-04
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EGF | smart00181 | Epidermal growth factor-like domain; |
1023-1055 | 6.30e-04 | |||
Epidermal growth factor-like domain; Pssm-ID: 214544 Cd Length: 35 Bit Score: 39.04 E-value: 6.30e-04
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EGF_CA | cd00054 | Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ... |
1784-1818 | 7.61e-04 | |||
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements. Pssm-ID: 238011 Cd Length: 38 Bit Score: 38.77 E-value: 7.61e-04
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EGF_CA | smart00179 | Calcium-binding EGF-like domain; |
1061-1102 | 7.73e-04 | |||
Calcium-binding EGF-like domain; Pssm-ID: 214542 [Multi-domain] Cd Length: 39 Bit Score: 38.77 E-value: 7.73e-04
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EGF_CA | pfam07645 | Calcium-binding EGF domain; |
940-969 | 1.30e-03 | |||
Calcium-binding EGF domain; Pssm-ID: 429571 Cd Length: 32 Bit Score: 37.99 E-value: 1.30e-03
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EGF_CA | pfam07645 | Calcium-binding EGF domain; |
1784-1817 | 1.69e-03 | |||
Calcium-binding EGF domain; Pssm-ID: 429571 Cd Length: 32 Bit Score: 37.60 E-value: 1.69e-03
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EGF | smart00181 | Epidermal growth factor-like domain; |
943-975 | 1.70e-03 | |||
Epidermal growth factor-like domain; Pssm-ID: 214544 Cd Length: 35 Bit Score: 37.50 E-value: 1.70e-03
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PHA03378 | PHA03378 | EBNA-3B; Provisional |
756-854 | 1.89e-03 | |||
EBNA-3B; Provisional Pssm-ID: 223065 [Multi-domain] Cd Length: 991 Bit Score: 43.13 E-value: 1.89e-03
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EGF_CA | smart00179 | Calcium-binding EGF-like domain; |
1495-1528 | 2.20e-03 | |||
Calcium-binding EGF-like domain; Pssm-ID: 214542 [Multi-domain] Cd Length: 39 Bit Score: 37.23 E-value: 2.20e-03
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EGF_CA | smart00179 | Calcium-binding EGF-like domain; |
1103-1144 | 2.65e-03 | |||
Calcium-binding EGF-like domain; Pssm-ID: 214542 [Multi-domain] Cd Length: 39 Bit Score: 37.23 E-value: 2.65e-03
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EGF_CA | smart00179 | Calcium-binding EGF-like domain; |
980-1011 | 3.01e-03 | |||
Calcium-binding EGF-like domain; Pssm-ID: 214542 [Multi-domain] Cd Length: 39 Bit Score: 36.84 E-value: 3.01e-03
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EGF | pfam00008 | EGF-like domain; There is no clear separation between noise and signal. pfam00053 is very ... |
901-928 | 4.48e-03 | |||
EGF-like domain; There is no clear separation between noise and signal. pfam00053 is very similar, but has 8 instead of 6 conserved cysteines. Includes some cytokine receptors. The EGF domain misses the N-terminus regions of the Ca2+ binding EGF domains (this is the main reason of discrepancy between swiss-prot domain start/end and Pfam). The family is hard to model due to many similar but different sub-types of EGF domains. Pfam certainly misses a number of EGF domains. Pssm-ID: 394967 Cd Length: 31 Bit Score: 36.21 E-value: 4.48e-03
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EGF | cd00053 | Epidermal growth factor domain, found in epidermal growth factor (EGF) presents in a large ... |
1316-1345 | 4.78e-03 | |||
Epidermal growth factor domain, found in epidermal growth factor (EGF) presents in a large number of proteins, mostly animal; the list of proteins currently known to contain one or more copies of an EGF-like pattern is large and varied; the functional significance of EGF-like domains in what appear to be unrelated proteins is not yet clear; a common feature is that these repeats are found in the extracellular domain of membrane-bound proteins or in proteins known to be secreted (exception: prostaglandin G/H synthase); the domain includes six cysteine residues which have been shown to be involved in disulfide bonds; the main structure is a two-stranded beta-sheet followed by a loop to a C-terminal short two-stranded sheet; Subdomains between the conserved cysteines vary in length; the region between the 5th and 6th cysteine contains two conserved glycines of which at least one is present in most EGF-like domains; a subset of these bind calcium. Pssm-ID: 238010 Cd Length: 36 Bit Score: 36.30 E-value: 4.78e-03
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cEGF | pfam12662 | Complement Clr-like EGF-like; cEGF, or complement Clr-like EGF, domains have six conserved ... |
1043-1064 | 5.42e-03 | |||
Complement Clr-like EGF-like; cEGF, or complement Clr-like EGF, domains have six conserved cysteine residues disulfide-bonded into the characteriztic pattern 'ababcc'. They are found in blood coagulation proteins such as fibrillin, Clr and Cls, thrombomodulin, and the LDL receptor. The core fold of the EGF domain consists of two small beta-hairpins packed against each other. Two major structural variants have been identified based on the structural context of the C-terminal cysteine residue of disulfide 'c' in the C-terminal hairpin: hEGFs and cEGFs. In cEGFs the C-terminal thiol resides on the C-terminal beta-sheet, resulting in long loop-lengths between the cysteine residues of disulfide 'c', typically C[10+]XC. These longer loop-lengths may have arisen by selective cysteine loss from a four-disulfide EGF template such as laminin or integrin. Tandem cEGF domains have five linking residues between terminal cysteines of adjacent domains. cEGF domains may or may not bind calcium in the linker region. cEGF domains with the consensus motif CXN4X[F,Y]XCXC are hydroxylated exclusively on the asparagine residue. Pssm-ID: 463661 Cd Length: 22 Bit Score: 35.85 E-value: 5.42e-03
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EGF_CA | cd00054 | Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular ... |
1103-1144 | 6.20e-03 | |||
Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the N-terminus of particular EGF-like domains; calcium-binding may be crucial for numerous protein-protein interactions. Six conserved core cysteines form three disulfide bridges as in non calcium-binding EGF domains, whose structures are very similar. EGF_CA can be found in tandem repeat arrangements. Pssm-ID: 238011 Cd Length: 38 Bit Score: 36.08 E-value: 6.20e-03
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TB | pfam00683 | TB domain; This domain is also known as the 8 cysteine domain. This family includes the hybrid ... |
567-601 | 8.20e-03 | |||
TB domain; This domain is also known as the 8 cysteine domain. This family includes the hybrid domains. This cysteine rich repeat is found in TGF binding protein and fibrillin. Pssm-ID: 459903 Cd Length: 44 Bit Score: 36.10 E-value: 8.20e-03
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Blast search parameters | ||||
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