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KN motif and ankyrin repeat domain-containing protein 2 isoform X1 [Rattus norvegicus]
List of domain hits
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Name | Accession | Description | Interval | E-value | ||||
ANKYR | COG0666 | Ankyrin repeat [Signal transduction mechanisms]; |
646-821 | 4.74e-33 | ||||
Ankyrin repeat [Signal transduction mechanisms]; : Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 129.30 E-value: 4.74e-33
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KN_motif super family | cl13504 | KN motif; This small motif is found at the N-terminus of Kank proteins and has been called the ... |
31-59 | 1.99e-14 | ||||
KN motif; This small motif is found at the N-terminus of Kank proteins and has been called the KN (for Kank N-terminal) motif. This protein is found in eukaryotes. Proteins in this family are typically between 413 to 1202 amino acids in length. This protein is found associated with pfam00023. This protein has two conserved sequence motifs: TPYG and LDLDF. Kank1 was obtained by positional cloning of a tumor suppressor gene in renal cell carcinoma, while the other members were found by homology search. The family is involved in the regulation of actin polymerization and cell motility through signaling pathways containing PI3K/Akt and/or unidentified modulators/effectors. The actual alignment was detected with superfamily member pfam12075: Pssm-ID: 432311 Cd Length: 39 Bit Score: 67.76 E-value: 1.99e-14
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Name | Accession | Description | Interval | E-value | ||||
ANKYR | COG0666 | Ankyrin repeat [Signal transduction mechanisms]; |
646-821 | 4.74e-33 | ||||
Ankyrin repeat [Signal transduction mechanisms]; Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 129.30 E-value: 4.74e-33
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Ank_2 | pfam12796 | Ankyrin repeats (3 copies); |
739-824 | 8.04e-20 | ||||
Ankyrin repeats (3 copies); Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 84.78 E-value: 8.04e-20
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KN_motif | pfam12075 | KN motif; This small motif is found at the N-terminus of Kank proteins and has been called the ... |
31-59 | 1.99e-14 | ||||
KN motif; This small motif is found at the N-terminus of Kank proteins and has been called the KN (for Kank N-terminal) motif. This protein is found in eukaryotes. Proteins in this family are typically between 413 to 1202 amino acids in length. This protein is found associated with pfam00023. This protein has two conserved sequence motifs: TPYG and LDLDF. Kank1 was obtained by positional cloning of a tumor suppressor gene in renal cell carcinoma, while the other members were found by homology search. The family is involved in the regulation of actin polymerization and cell motility through signaling pathways containing PI3K/Akt and/or unidentified modulators/effectors. Pssm-ID: 432311 Cd Length: 39 Bit Score: 67.76 E-value: 1.99e-14
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PHA03100 | PHA03100 | ankyrin repeat protein; Provisional |
651-788 | 9.16e-08 | ||||
ankyrin repeat protein; Provisional Pssm-ID: 222984 [Multi-domain] Cd Length: 422 Bit Score: 55.44 E-value: 9.16e-08
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ANK | smart00248 | ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ... |
735-763 | 2.54e-04 | ||||
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four consecutive copies. They are involved in protein-protein interactions. The core of the repeat seems to be an helix-loop-helix structure. Pssm-ID: 197603 [Multi-domain] Cd Length: 30 Bit Score: 38.72 E-value: 2.54e-04
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Name | Accession | Description | Interval | E-value | ||||
ANKYR | COG0666 | Ankyrin repeat [Signal transduction mechanisms]; |
646-821 | 4.74e-33 | ||||
Ankyrin repeat [Signal transduction mechanisms]; Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 129.30 E-value: 4.74e-33
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ANKYR | COG0666 | Ankyrin repeat [Signal transduction mechanisms]; |
624-821 | 3.41e-28 | ||||
Ankyrin repeat [Signal transduction mechanisms]; Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 115.44 E-value: 3.41e-28
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ANKYR | COG0666 | Ankyrin repeat [Signal transduction mechanisms]; |
624-818 | 6.39e-28 | ||||
Ankyrin repeat [Signal transduction mechanisms]; Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 114.67 E-value: 6.39e-28
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ANKYR | COG0666 | Ankyrin repeat [Signal transduction mechanisms]; |
649-821 | 1.51e-21 | ||||
Ankyrin repeat [Signal transduction mechanisms]; Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 95.79 E-value: 1.51e-21
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Ank_2 | pfam12796 | Ankyrin repeats (3 copies); |
739-824 | 8.04e-20 | ||||
Ankyrin repeats (3 copies); Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 84.78 E-value: 8.04e-20
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ANKYR | COG0666 | Ankyrin repeat [Signal transduction mechanisms]; |
624-789 | 1.85e-18 | ||||
Ankyrin repeat [Signal transduction mechanisms]; Pssm-ID: 440430 [Multi-domain] Cd Length: 289 Bit Score: 86.93 E-value: 1.85e-18
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KN_motif | pfam12075 | KN motif; This small motif is found at the N-terminus of Kank proteins and has been called the ... |
31-59 | 1.99e-14 | ||||
KN motif; This small motif is found at the N-terminus of Kank proteins and has been called the KN (for Kank N-terminal) motif. This protein is found in eukaryotes. Proteins in this family are typically between 413 to 1202 amino acids in length. This protein is found associated with pfam00023. This protein has two conserved sequence motifs: TPYG and LDLDF. Kank1 was obtained by positional cloning of a tumor suppressor gene in renal cell carcinoma, while the other members were found by homology search. The family is involved in the regulation of actin polymerization and cell motility through signaling pathways containing PI3K/Akt and/or unidentified modulators/effectors. Pssm-ID: 432311 Cd Length: 39 Bit Score: 67.76 E-value: 1.99e-14
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Ank_2 | pfam12796 | Ankyrin repeats (3 copies); |
667-765 | 1.33e-13 | ||||
Ankyrin repeats (3 copies); Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 67.06 E-value: 1.33e-13
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Ank_4 | pfam13637 | Ankyrin repeats (many copies); |
737-788 | 2.40e-10 | ||||
Ankyrin repeats (many copies); Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 56.51 E-value: 2.40e-10
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Ank_5 | pfam13857 | Ankyrin repeats (many copies); |
719-772 | 5.90e-08 | ||||
Ankyrin repeats (many copies); Pssm-ID: 433530 [Multi-domain] Cd Length: 56 Bit Score: 50.04 E-value: 5.90e-08
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PHA03100 | PHA03100 | ankyrin repeat protein; Provisional |
651-788 | 9.16e-08 | ||||
ankyrin repeat protein; Provisional Pssm-ID: 222984 [Multi-domain] Cd Length: 422 Bit Score: 55.44 E-value: 9.16e-08
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PHA02878 | PHA02878 | ankyrin repeat protein; Provisional |
656-775 | 1.51e-06 | ||||
ankyrin repeat protein; Provisional Pssm-ID: 222939 [Multi-domain] Cd Length: 477 Bit Score: 51.80 E-value: 1.51e-06
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Ank_2 | pfam12796 | Ankyrin repeats (3 copies); |
772-829 | 2.53e-06 | ||||
Ankyrin repeats (3 copies); Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 46.26 E-value: 2.53e-06
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PTZ00322 | PTZ00322 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional |
751-823 | 3.48e-06 | ||||
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 50.67 E-value: 3.48e-06
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PHA03095 | PHA03095 | ankyrin-like protein; Provisional |
640-756 | 3.51e-06 | ||||
ankyrin-like protein; Provisional Pssm-ID: 222980 [Multi-domain] Cd Length: 471 Bit Score: 50.41 E-value: 3.51e-06
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PHA03095 | PHA03095 | ankyrin-like protein; Provisional |
656-774 | 8.54e-06 | ||||
ankyrin-like protein; Provisional Pssm-ID: 222980 [Multi-domain] Cd Length: 471 Bit Score: 49.25 E-value: 8.54e-06
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Ank_3 | pfam13606 | Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ... |
735-763 | 1.37e-05 | ||||
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities. Pssm-ID: 463933 [Multi-domain] Cd Length: 30 Bit Score: 42.63 E-value: 1.37e-05
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PLN03192 | PLN03192 | Voltage-dependent potassium channel; Provisional |
657-788 | 1.38e-05 | ||||
Voltage-dependent potassium channel; Provisional Pssm-ID: 215625 [Multi-domain] Cd Length: 823 Bit Score: 48.71 E-value: 1.38e-05
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Ank_5 | pfam13857 | Ankyrin repeats (many copies); |
754-809 | 2.63e-05 | ||||
Ankyrin repeats (many copies); Pssm-ID: 433530 [Multi-domain] Cd Length: 56 Bit Score: 42.33 E-value: 2.63e-05
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Ank | pfam00023 | Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ... |
735-766 | 3.30e-05 | ||||
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities. Repeats 13-24 are especially active, with known sites of interaction for the Na/K ATPase, Cl/HCO(3) anion exchanger, voltage-gated sodium channel, clathrin heavy chain and L1 family cell adhesion molecules. The ANK repeats are found to form a contiguous spiral stack such that ion transporters like the anion exchanger associate in a large central cavity formed by the ANK repeat spiral, while clathrin and cell adhesion molecules associate with specific regions outside this cavity. Pssm-ID: 459634 [Multi-domain] Cd Length: 34 Bit Score: 41.51 E-value: 3.30e-05
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PHA02875 | PHA02875 | ankyrin repeat protein; Provisional |
667-824 | 4.66e-05 | ||||
ankyrin repeat protein; Provisional Pssm-ID: 165206 [Multi-domain] Cd Length: 413 Bit Score: 46.52 E-value: 4.66e-05
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Ank_4 | pfam13637 | Ankyrin repeats (many copies); |
768-821 | 6.50e-05 | ||||
Ankyrin repeats (many copies); Pssm-ID: 372654 [Multi-domain] Cd Length: 54 Bit Score: 41.11 E-value: 6.50e-05
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PHA03095 | PHA03095 | ankyrin-like protein; Provisional |
672-810 | 8.20e-05 | ||||
ankyrin-like protein; Provisional Pssm-ID: 222980 [Multi-domain] Cd Length: 471 Bit Score: 46.17 E-value: 8.20e-05
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PLN03192 | PLN03192 | Voltage-dependent potassium channel; Provisional |
735-821 | 8.20e-05 | ||||
Voltage-dependent potassium channel; Provisional Pssm-ID: 215625 [Multi-domain] Cd Length: 823 Bit Score: 46.40 E-value: 8.20e-05
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PHA03095 | PHA03095 | ankyrin-like protein; Provisional |
656-810 | 8.49e-05 | ||||
ankyrin-like protein; Provisional Pssm-ID: 222980 [Multi-domain] Cd Length: 471 Bit Score: 46.17 E-value: 8.49e-05
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PLN03192 | PLN03192 | Voltage-dependent potassium channel; Provisional |
739-836 | 8.71e-05 | ||||
Voltage-dependent potassium channel; Provisional Pssm-ID: 215625 [Multi-domain] Cd Length: 823 Bit Score: 46.40 E-value: 8.71e-05
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PTZ00322 | PTZ00322 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional |
735-797 | 1.29e-04 | ||||
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional Pssm-ID: 140343 [Multi-domain] Cd Length: 664 Bit Score: 45.66 E-value: 1.29e-04
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ANK | smart00248 | ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ... |
735-763 | 2.54e-04 | ||||
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four consecutive copies. They are involved in protein-protein interactions. The core of the repeat seems to be an helix-loop-helix structure. Pssm-ID: 197603 [Multi-domain] Cd Length: 30 Bit Score: 38.72 E-value: 2.54e-04
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Ank_2 | pfam12796 | Ankyrin repeats (3 copies); |
624-687 | 3.00e-04 | ||||
Ankyrin repeats (3 copies); Pssm-ID: 463710 [Multi-domain] Cd Length: 91 Bit Score: 40.48 E-value: 3.00e-04
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PHA03095 | PHA03095 | ankyrin-like protein; Provisional |
651-809 | 3.43e-04 | ||||
ankyrin-like protein; Provisional Pssm-ID: 222980 [Multi-domain] Cd Length: 471 Bit Score: 43.86 E-value: 3.43e-04
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PHA02878 | PHA02878 | ankyrin repeat protein; Provisional |
656-810 | 5.82e-04 | ||||
ankyrin repeat protein; Provisional Pssm-ID: 222939 [Multi-domain] Cd Length: 477 Bit Score: 43.33 E-value: 5.82e-04
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PLN03192 | PLN03192 | Voltage-dependent potassium channel; Provisional |
656-772 | 6.50e-04 | ||||
Voltage-dependent potassium channel; Provisional Pssm-ID: 215625 [Multi-domain] Cd Length: 823 Bit Score: 43.32 E-value: 6.50e-04
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ANK | smart00248 | ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four ... |
662-687 | 7.04e-03 | ||||
ankyrin repeats; Ankyrin repeats are about 33 amino acids long and occur in at least four consecutive copies. They are involved in protein-protein interactions. The core of the repeat seems to be an helix-loop-helix structure. Pssm-ID: 197603 [Multi-domain] Cd Length: 30 Bit Score: 34.87 E-value: 7.04e-03
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Ank_3 | pfam13606 | Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the ... |
662-687 | 7.19e-03 | ||||
Ankyrin repeat; Ankyrins are multifunctional adaptors that link specific proteins to the membrane-associated, spectrin- actin cytoskeleton. This repeat-domain is a 'membrane-binding' domain of up to 24 repeated units, and it mediates most of the protein's binding activities. Pssm-ID: 463933 [Multi-domain] Cd Length: 30 Bit Score: 34.93 E-value: 7.19e-03
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Blast search parameters | ||||
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