|
Name |
Accession |
Description |
Interval |
E-value |
| TSPN |
smart00210 |
Thrombospondin N-terminal -like domains; Heparin-binding and cell adhesion domain of ... |
50-231 |
6.24e-57 |
|
Thrombospondin N-terminal -like domains; Heparin-binding and cell adhesion domain of thrombospondin
Pssm-ID: 214560 Cd Length: 184 Bit Score: 194.11 E-value: 6.24e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 50 GFNLIRRLNLM-KTSAIKKIRNPKGP-LILRLG-AAPVTQPTRRVFPRGLPEEFALVLTVLLKKhtfRNTWYLFQVTDAN 126
Cdd:smart00210 1 GQDLLQVFDLPsLSFAIRQVVGPEPGsPAYRLGdPALVPQPTRDLFPSGLPEDFSLLTTFRQTP---KSRGVLFAIYDAQ 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 127 GYPQISLEVNSQERSLELRAQGQDGDFVSCIFPVPQLFDLRWHKLMLSVAGRVASVHVDCVSASSQPLGPR--QSIRPGG 204
Cdd:smart00210 78 NVRQFGLEVDGRANTLLLRYQGVDGKQHTVSFRNLPLADGQWHKLALSVSGSSATLYVDCNEIDSRPLDRPgqPPIDTDG 157
|
170 180
....*....|....*....|....*..
gi 568928185 205 HVFLGLDAEQGKPVSFDLQQAHIYCDP 231
Cdd:smart00210 158 IEVRGAQAADRKPFQGDLQQLKIVCDP 184
|
|
| gly_rich_SclB |
NF038329 |
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ... |
665-868 |
7.04e-28 |
|
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.
Pssm-ID: 468478 [Multi-domain] Cd Length: 440 Bit Score: 118.08 E-value: 7.04e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 665 GEKGEPGSPG-FGLPGKQGKAGERGLKGQKGDAGNPGDPGTPGITGQPGISGEPGIRGPAGPKGEKGDgctacpslqgal 743
Cdd:NF038329 117 GEKGEPGPAGpAGPAGEQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPAGKDGEAGA------------ 184
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 744 tdvsglPGKPGPKGEPGPEG-VGHPGKPGQPGLPGVQGPPGPKGTQGEPGPPGTGAEGPQGEPGTQGLPGTQGLPGPRGP 822
Cdd:NF038329 185 ------KGPAGEKGPQGPRGeTGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAGDGQQGPDGDPGPTGEDGPQGPDGPAGK 258
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 568928185 823 PGSAGEKGAQGSPGPKGAIGPMGPPGA-------GVSGPPGQKGSRGEKGEPG 868
Cdd:NF038329 259 DGPRGDRGEAGPDGPDGKDGERGPVGPagkdgqnGKDGLPGKDGKDGQNGKDG 311
|
|
| gly_rich_SclB |
NF038329 |
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ... |
544-794 |
7.35e-27 |
|
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.
Pssm-ID: 468478 [Multi-domain] Cd Length: 440 Bit Score: 115.00 E-value: 7.35e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 544 EGLGTVGLKGDRGDPGIQGMKGEKGEPcsscssgvgaqhlgpspghGLPGLPGTSGIPGPRGLKGEKGSFGDTGPAGVPG 623
Cdd:NF038329 108 EGLQQLKGDGEKGEPGPAGPAGPAGEQ-------------------GPRGDRGETGPAGPAGPPGPQGERGEKGPAGPQG 168
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 624 SPGPVGPA------------GIKGAKGEPCEPCTALSELQDGDMRVVHLPGPAGEKGEPGSPGFGLPGKQGKAGERGLKG 691
Cdd:NF038329 169 EAGPQGPAgkdgeagakgpaGEKGPQGPRGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAGDGQQGPDGDPGPTGEDG 248
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 692 QKGDAGNPGDPGTPGITGQPGISGEPGIRGPAGPKGEKGdgctacpslQGALTDVSGLPGKPGPKGEPGPEGVghPGKPG 771
Cdd:NF038329 249 PQGPDGPAGKDGPRGDRGEAGPDGPDGKDGERGPVGPAG---------KDGQNGKDGLPGKDGKDGQNGKDGL--PGKDG 317
|
250 260
....*....|....*....|...
gi 568928185 772 QPGLPGVQGPPGPKGTQGEPGPP 794
Cdd:NF038329 318 KDGQPGKDGLPGKDGKDGQPGKP 340
|
|
| gly_rich_SclB |
NF038329 |
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ... |
503-725 |
1.96e-23 |
|
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.
Pssm-ID: 468478 [Multi-domain] Cd Length: 440 Bit Score: 104.60 E-value: 1.96e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 503 KGEKGDPCEVCPTLPEGSQNFVGLPGKPGPKGEPGDPAPAWEGlGTVGLKGDRGDPGIQGMKGEKGEPCSSCSSGVGaqh 582
Cdd:NF038329 134 QGPRGDRGETGPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPA-GKDGEAGAKGPAGEKGPQGPRGETGPAGEQGPA--- 209
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 583 lGPSPGHGLPGLPGTSGIPGPRGlKGEKGSFGDTGPAGVPGSPGPVGPAGIKGAKGEPCEPCTALSELQDGDMrvvHLPG 662
Cdd:NF038329 210 -GPAGPDGEAGPAGEDGPAGPAG-DGQQGPDGDPGPTGEDGPQGPDGPAGKDGPRGDRGEAGPDGPDGKDGER---GPVG 284
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568928185 663 PAGEKGEPGSPGfgLPGKQGKAGERGLKGQKGDAGNPGDPGTPGITGQPGISGEPGIRGPAGP 725
Cdd:NF038329 285 PAGKDGQNGKDG--LPGKDGKDGQNGKDGLPGKDGKDGQPGKDGLPGKDGKDGQPGKPAPKTP 345
|
|
| gly_rich_SclB |
NF038329 |
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ... |
335-705 |
3.20e-18 |
|
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.
Pssm-ID: 468478 [Multi-domain] Cd Length: 440 Bit Score: 88.42 E-value: 3.20e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 335 LKGGKGERGLTGPSGPKGEKgargndcvrvspdaplqcveGPKGEKGEsgdlgppglpgpTGQKGQKGEKGDGGLKGLPG 414
Cdd:NF038329 115 GDGEKGEPGPAGPAGPAGEQ--------------------GPRGDRGE------------TGPAGPAGPPGPQGERGEKG 162
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 415 KPGRDGRPGEICVIGPKGQKGDPGFVGPeglagepgppglpgppgiglpgtpgdpggppgpkgekgssgipgkegpggkp 494
Cdd:NF038329 163 PAGPQGEAGPQGPAGKDGEAGAKGPAGE---------------------------------------------------- 190
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 495 gkpgvpgtKGEKGDPCEVCPTLPEGSQNFVGLPGKPGPKGEPGDPAPAweGLGTVGLKGDRGDPGIQGMKGEKGEpcssc 574
Cdd:NF038329 191 --------KGPQGPRGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPA--GDGQQGPDGDPGPTGEDGPQGPDGP----- 255
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 575 ssgvgaqhlgpspghglpglpgtsgiPGPRGLKGEKGSFGDTGPAGVPGSPGPVGPAGIKGAKGepcepctalselQDGd 654
Cdd:NF038329 256 --------------------------AGKDGPRGDRGEAGPDGPDGKDGERGPVGPAGKDGQNG------------KDG- 296
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|.
gi 568928185 655 mrvvhLPGPAGEKGEPGSPgfGLPGKQGKAGERGLKGQKGDAGNPGDPGTP 705
Cdd:NF038329 297 -----LPGKDGKDGQNGKD--GLPGKDGKDGQPGKDGLPGKDGKDGQPGKP 340
|
|
| gly_rich_SclB |
NF038329 |
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ... |
754-935 |
1.37e-11 |
|
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.
Pssm-ID: 468478 [Multi-domain] Cd Length: 440 Bit Score: 67.62 E-value: 1.37e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 754 GPKGEPGPEG-VGHPGKPGQPGLPGVQGPPGPKGTQGEPGPPG-TGAEGPQGEPGTQGLPGTQGLPGPRGPPGSAGEKGA 831
Cdd:NF038329 117 GEKGEPGPAGpAGPAGEQGPRGDRGETGPAGPAGPPGPQGERGeKGPAGPQGEAGPQGPAGKDGEAGAKGPAGEKGPQGP 196
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 832 QGSPGPKGAIGPMGPPGagvsgPPGQKGSRGEKGEPGECSCPSRGEpifsgmpgapglwmgsssqpgpqgpPGVPGPPGP 911
Cdd:NF038329 197 RGETGPAGEQGPAGPAG-----PDGEAGPAGEDGPAGPAGDGQQGP-------------------------DGDPGPTGE 246
|
170 180
....*....|....*....|....
gi 568928185 912 PGMPGLQGVPGHNGLPGQPGLTAE 935
Cdd:NF038329 247 DGPQGPDGPAGKDGPRGDRGEAGP 270
|
|
| SPT5 |
COG5164 |
Transcription elongation factor SPT5 [Transcription]; |
595-855 |
1.29e-09 |
|
Transcription elongation factor SPT5 [Transcription];
Pssm-ID: 444063 [Multi-domain] Cd Length: 495 Bit Score: 61.58 E-value: 1.29e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 595 PGTSGIPGPRGLKGEKGSFGDTGPAGVPGSPGPVGPAGIKGAkgepcepctalselqdgdmrvvhlPGPAGEKGEPGSPG 674
Cdd:COG5164 6 PGKTGPSDPGGVTTPAGSQGSTKPAQNQGSTRPAGNTGGTRP------------------------AQNQGSTTPAGNTG 61
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 675 FGLP-GKQGKAGERGLKGQKGDAGNPGDPGTPGITGQPGISGEPGIRGPAGPKGEKGdgctacpslqGALTDVSGLPGKP 753
Cdd:COG5164 62 GTRPaGNQGATGPAQNQGGTTPAQNQGGTRPAGNTGGTTPAGDGGATGPPDDGGATG----------PPDDGGSTTPPSG 131
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 754 GPKGEPGPEGVGHPGkPGQPGLPGVQGPPGPKGTQGEPGPPGTGAEGPQGEPGTQGLPGTQGLPGPRGPPGSAGEKGAQG 833
Cdd:COG5164 132 GSTTPPGDGGSTPPG-PGSTGPGGSTTPPGDGGSTTPPGPGGSTTPPDDGGSTTPPNKGETGTDIPTGGTPRQGPDGPVK 210
|
250 260
....*....|....*....|..
gi 568928185 834 SPGPKGAIGPmgPPGAGVSGPP 855
Cdd:COG5164 211 KDDKNGKGNP--PDDRGGKTGP 230
|
|
| gly_rich_SclB |
NF038329 |
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ... |
331-541 |
5.07e-08 |
|
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.
Pssm-ID: 468478 [Multi-domain] Cd Length: 440 Bit Score: 56.45 E-value: 5.07e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 331 GPSGLKGGKGERGLTGPSGPKGEKGARGNDCVRVSPDAplqcvEGPKGEKGESGDLGPPGLPGPTGQKGQKGEKGDGGLK 410
Cdd:NF038329 147 GPAGPPGPQGERGEKGPAGPQGEAGPQGPAGKDGEAGA-----KGPAGEKGPQGPRGETGPAGEQGPAGPAGPDGEAGPA 221
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 411 GLPGKPGRDGRP--GEICVIGPKGQKGDPGFVGPEGLAGEPGPPGLPGPPGIGLPGTPGDPGGPPGPKGEKGSSGIPGKE 488
Cdd:NF038329 222 GEDGPAGPAGDGqqGPDGDPGPTGEDGPQGPDGPAGKDGPRGDRGEAGPDGPDGKDGERGPVGPAGKDGQNGKDGLPGKD 301
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 568928185 489 GPGGKPGKPGVPGTKGEKGDPCEvcptlpegsqnfVGLPGKPGPKGEPGDPAP 541
Cdd:NF038329 302 GKDGQNGKDGLPGKDGKDGQPGK------------DGLPGKDGKDGQPGKPAP 342
|
|
| gly_rich_SclB |
NF038329 |
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ... |
799-889 |
8.45e-07 |
|
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.
Pssm-ID: 468478 [Multi-domain] Cd Length: 440 Bit Score: 52.60 E-value: 8.45e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 799 EGPQGEPGTQGLPGTQGLPGPRGPPGSAGEKGAQGSPGPKGAIGPMGPPG----AGVSGPPGQKGSRGEKGEPGECSCP- 873
Cdd:NF038329 116 DGEKGEPGPAGPAGPAGEQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGpqgeAGPQGPAGKDGEAGAKGPAGEKGPQg 195
|
90
....*....|....*.
gi 568928185 874 SRGEPIFSGMPGAPGL 889
Cdd:NF038329 196 PRGETGPAGEQGPAGP 211
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
644-867 |
1.31e-05 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 49.21 E-value: 1.31e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 644 CTALSELQDGDMRVVHLPGPAgekgePGSPGFGLPGKQGKAGERGLKGQKGDAGNPGDPGTPGITGQPGISGEPGIRGPA 723
Cdd:PRK07764 571 VTALAEELGGDWQVEAVVGPA-----PGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAP 645
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 724 GPKGEKGDGctACPSLQGALTDVSGLPGKPGPKGEPGPEGVGHPGKPGQPGlPGVQGPPGPKGTQGEPGPPGTGAEGPQG 803
Cdd:PRK07764 646 GVAAPEHHP--KHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPA-GAAPAQPAPAPAATPPAGQADDPAAQPP 722
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568928185 804 EPGTQGLPGTQGLPGPRGPPGSAGEKGAQGSPGPKGAiGPMGPPGAGVSGPPGQKGSRGEKGEP 867
Cdd:PRK07764 723 QAAQGASAPSPAADDPVPLPPEPDDPPDPAGAPAQPP-PPPAPAPAAAPAAAPPPSPPSEEEEM 785
|
|
| Med15 |
pfam09606 |
ARC105 or Med15 subunit of Mediator complex non-fungal; The approx. 70 residue Med15 domain of ... |
619-869 |
1.05e-04 |
|
ARC105 or Med15 subunit of Mediator complex non-fungal; The approx. 70 residue Med15 domain of the ARC-Mediator co-activator is a three-helix bundle with marked similarity to the KIX domain. The sterol regulatory element binding protein (SREBP) family of transcription activators use the ARC105 subunit to activate target genes in the regulation of cholesterol and fatty acid homeostasis. In addition, Med15 is a critical transducer of gene activation signals that control early metazoan development.
Pssm-ID: 312941 [Multi-domain] Cd Length: 732 Bit Score: 46.15 E-value: 1.05e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 619 AGVPGSP-GPVGPAGIKGAKGEPCEPCTALSELQDGDMRVvhlPGPAGEKGEPGSPgfglpgkqgKAGERGLKGQKGDAG 697
Cdd:pfam09606 57 AAQQQQPqGGQGNGGMGGGQQGMPDPINALQNLAGQGTRP---QMMGPMGPGPGGP---------MGQQMGGPGTASNLL 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 698 NPGDPGTPGITGQPGISGEPGIRGPAGPKGEKGdgctacPSLQGALTDVSGLPGKPGPKGEPGPEGVghPGKPGQPGLPG 777
Cdd:pfam09606 125 ASLGRPQMPMGGAGFPSQMSRVGRMQPGGQAGG------MMQPSSGQPGSGTPNQMGPNGGPGQGQA--GGMNGGQQGPM 196
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 778 VQGPPGPKGTQGEPGPPGTGAEGPQGEPGTQGLPGTQGLPGPRGPPGSAGEKGAQGSPGPKGA-IGPMGPPGAGVSGPPG 856
Cdd:pfam09606 197 GGQMPPQMGVPGMPGPADAGAQMGQQAQANGGMNPQQMGGAPNQVAMQQQQPQQQGQQSQLGMgINQMQQMPQGVGGGAG 276
|
250
....*....|...
gi 568928185 857 QKGSRGEKGEPGE 869
Cdd:pfam09606 277 QGGPGQPMGPPGQ 289
|
|
| Collagen |
pfam01391 |
Collagen triple helix repeat (20 copies); Members of this family belong to the collagen ... |
590-643 |
2.57e-04 |
|
Collagen triple helix repeat (20 copies); Members of this family belong to the collagen superfamily. Collagens are generally extracellular structural proteins involved in formation of connective tissue structure. The alignment contains 20 copies of the G-X-Y repeat that forms a triple helix. The first position of the repeat is glycine, the second and third positions can be any residue but are frequently proline and hydroxy-proline. Collagens are post translationally modified by proline hydroxylase to form the hydroxy-proline residues. Defective hydroxylation is the cause of scurvy. Some members of the collagen superfamily are not involved in connective tissue structure but share the same triple helical structure. The family includes bacterial collagen-like triple-helix repeat proteins.
Pssm-ID: 460189 [Multi-domain] Cd Length: 57 Bit Score: 39.78 E-value: 2.57e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 568928185 590 GLPGLPGTSGIPGPRGLKGEKGSFGDTGPAGVPGSPGPVGPAGIKGAKGEPCEP 643
Cdd:pfam01391 1 GPPGPPGPPGPPGPPGPPGPPGPPGPPGPPGEPGPPGPPGPPGPPGPPGAPGAP 54
|
|
| dermokine |
cd21118 |
dermokine; Dermokine, also known as epidermis-specific secreted protein SK30/SK89, is a ... |
671-888 |
5.29e-03 |
|
dermokine; Dermokine, also known as epidermis-specific secreted protein SK30/SK89, is a skin-specific glycoprotein that may play a regulatory role in the crosstalk between barrier dysfunction and inflammation, and therefore play a role in inflammatory diseases such as psoriasis. Dermokine is one of the most highly expressed proteins in differentiating keratinocytes, found mainly in the spinous and granular layers of the epidermis, but also in the epithelia of the small intestine, macrophages of the lung, and endothelial cells of the lung. Mouse dermokine has been reported to be encoded by 22 exons, and its expression leads to alpha, beta, and gamma transcripts.
Pssm-ID: 411053 [Multi-domain] Cd Length: 495 Bit Score: 40.37 E-value: 5.29e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 671 GSPGFGLPGKQGKAGERGlkgqkgdAGNPGDPGTPGITGQP-GISGEPGIRGPAGPKGEKGDGCTAcpslQGAltdvSGL 749
Cdd:cd21118 123 GSGGHGAYGSQGGPGVQG-------HGIPGGTGGPWASGGNyGTNSLGGSVGQGGNGGPLNYGTNS----QGA----VAQ 187
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 750 PGKPGPKGEPGPEGVGHPGKPGQPGLPGVQGPPGPKGTQGEPGPPGTGAEGPQGEPGTQGLPGTQGLPGPRGPPGSAGEK 829
Cdd:cd21118 188 PGYGTVRGNNQNSGCTNPPPSGSHESFSNSGGSSSSGSSGSQGSHGSNGQGSSGSSGGQGNGGNNGSSSSNSGNSGGSNG 267
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 830 GAQG-SPGPKGAIGPMGPPGAGVSGPPGQKGSRGEKGEPgECSCPSRGepifSGMPGAPG 888
Cdd:cd21118 268 GSSGnSGSGSGGSSSGGSNGWGGSSSSGGSGGSGGGNKP-ECNNPGND----VRMAGGGG 322
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| TSPN |
smart00210 |
Thrombospondin N-terminal -like domains; Heparin-binding and cell adhesion domain of ... |
50-231 |
6.24e-57 |
|
Thrombospondin N-terminal -like domains; Heparin-binding and cell adhesion domain of thrombospondin
Pssm-ID: 214560 Cd Length: 184 Bit Score: 194.11 E-value: 6.24e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 50 GFNLIRRLNLM-KTSAIKKIRNPKGP-LILRLG-AAPVTQPTRRVFPRGLPEEFALVLTVLLKKhtfRNTWYLFQVTDAN 126
Cdd:smart00210 1 GQDLLQVFDLPsLSFAIRQVVGPEPGsPAYRLGdPALVPQPTRDLFPSGLPEDFSLLTTFRQTP---KSRGVLFAIYDAQ 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 127 GYPQISLEVNSQERSLELRAQGQDGDFVSCIFPVPQLFDLRWHKLMLSVAGRVASVHVDCVSASSQPLGPR--QSIRPGG 204
Cdd:smart00210 78 NVRQFGLEVDGRANTLLLRYQGVDGKQHTVSFRNLPLADGQWHKLALSVSGSSATLYVDCNEIDSRPLDRPgqPPIDTDG 157
|
170 180
....*....|....*....|....*..
gi 568928185 205 HVFLGLDAEQGKPVSFDLQQAHIYCDP 231
Cdd:smart00210 158 IEVRGAQAADRKPFQGDLQQLKIVCDP 184
|
|
| gly_rich_SclB |
NF038329 |
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ... |
665-868 |
7.04e-28 |
|
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.
Pssm-ID: 468478 [Multi-domain] Cd Length: 440 Bit Score: 118.08 E-value: 7.04e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 665 GEKGEPGSPG-FGLPGKQGKAGERGLKGQKGDAGNPGDPGTPGITGQPGISGEPGIRGPAGPKGEKGDgctacpslqgal 743
Cdd:NF038329 117 GEKGEPGPAGpAGPAGEQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPAGKDGEAGA------------ 184
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 744 tdvsglPGKPGPKGEPGPEG-VGHPGKPGQPGLPGVQGPPGPKGTQGEPGPPGTGAEGPQGEPGTQGLPGTQGLPGPRGP 822
Cdd:NF038329 185 ------KGPAGEKGPQGPRGeTGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAGDGQQGPDGDPGPTGEDGPQGPDGPAGK 258
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 568928185 823 PGSAGEKGAQGSPGPKGAIGPMGPPGA-------GVSGPPGQKGSRGEKGEPG 868
Cdd:NF038329 259 DGPRGDRGEAGPDGPDGKDGERGPVGPagkdgqnGKDGLPGKDGKDGQNGKDG 311
|
|
| gly_rich_SclB |
NF038329 |
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ... |
544-794 |
7.35e-27 |
|
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.
Pssm-ID: 468478 [Multi-domain] Cd Length: 440 Bit Score: 115.00 E-value: 7.35e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 544 EGLGTVGLKGDRGDPGIQGMKGEKGEPcsscssgvgaqhlgpspghGLPGLPGTSGIPGPRGLKGEKGSFGDTGPAGVPG 623
Cdd:NF038329 108 EGLQQLKGDGEKGEPGPAGPAGPAGEQ-------------------GPRGDRGETGPAGPAGPPGPQGERGEKGPAGPQG 168
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 624 SPGPVGPA------------GIKGAKGEPCEPCTALSELQDGDMRVVHLPGPAGEKGEPGSPGFGLPGKQGKAGERGLKG 691
Cdd:NF038329 169 EAGPQGPAgkdgeagakgpaGEKGPQGPRGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAGDGQQGPDGDPGPTGEDG 248
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 692 QKGDAGNPGDPGTPGITGQPGISGEPGIRGPAGPKGEKGdgctacpslQGALTDVSGLPGKPGPKGEPGPEGVghPGKPG 771
Cdd:NF038329 249 PQGPDGPAGKDGPRGDRGEAGPDGPDGKDGERGPVGPAG---------KDGQNGKDGLPGKDGKDGQNGKDGL--PGKDG 317
|
250 260
....*....|....*....|...
gi 568928185 772 QPGLPGVQGPPGPKGTQGEPGPP 794
Cdd:NF038329 318 KDGQPGKDGLPGKDGKDGQPGKP 340
|
|
| gly_rich_SclB |
NF038329 |
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ... |
503-725 |
1.96e-23 |
|
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.
Pssm-ID: 468478 [Multi-domain] Cd Length: 440 Bit Score: 104.60 E-value: 1.96e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 503 KGEKGDPCEVCPTLPEGSQNFVGLPGKPGPKGEPGDPAPAWEGlGTVGLKGDRGDPGIQGMKGEKGEPCSSCSSGVGaqh 582
Cdd:NF038329 134 QGPRGDRGETGPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPA-GKDGEAGAKGPAGEKGPQGPRGETGPAGEQGPA--- 209
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 583 lGPSPGHGLPGLPGTSGIPGPRGlKGEKGSFGDTGPAGVPGSPGPVGPAGIKGAKGEPCEPCTALSELQDGDMrvvHLPG 662
Cdd:NF038329 210 -GPAGPDGEAGPAGEDGPAGPAG-DGQQGPDGDPGPTGEDGPQGPDGPAGKDGPRGDRGEAGPDGPDGKDGER---GPVG 284
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568928185 663 PAGEKGEPGSPGfgLPGKQGKAGERGLKGQKGDAGNPGDPGTPGITGQPGISGEPGIRGPAGP 725
Cdd:NF038329 285 PAGKDGQNGKDG--LPGKDGKDGQNGKDGLPGKDGKDGQPGKDGLPGKDGKDGQPGKPAPKTP 345
|
|
| gly_rich_SclB |
NF038329 |
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ... |
335-705 |
3.20e-18 |
|
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.
Pssm-ID: 468478 [Multi-domain] Cd Length: 440 Bit Score: 88.42 E-value: 3.20e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 335 LKGGKGERGLTGPSGPKGEKgargndcvrvspdaplqcveGPKGEKGEsgdlgppglpgpTGQKGQKGEKGDGGLKGLPG 414
Cdd:NF038329 115 GDGEKGEPGPAGPAGPAGEQ--------------------GPRGDRGE------------TGPAGPAGPPGPQGERGEKG 162
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 415 KPGRDGRPGEICVIGPKGQKGDPGFVGPeglagepgppglpgppgiglpgtpgdpggppgpkgekgssgipgkegpggkp 494
Cdd:NF038329 163 PAGPQGEAGPQGPAGKDGEAGAKGPAGE---------------------------------------------------- 190
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 495 gkpgvpgtKGEKGDPCEVCPTLPEGSQNFVGLPGKPGPKGEPGDPAPAweGLGTVGLKGDRGDPGIQGMKGEKGEpcssc 574
Cdd:NF038329 191 --------KGPQGPRGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPA--GDGQQGPDGDPGPTGEDGPQGPDGP----- 255
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 575 ssgvgaqhlgpspghglpglpgtsgiPGPRGLKGEKGSFGDTGPAGVPGSPGPVGPAGIKGAKGepcepctalselQDGd 654
Cdd:NF038329 256 --------------------------AGKDGPRGDRGEAGPDGPDGKDGERGPVGPAGKDGQNG------------KDG- 296
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|.
gi 568928185 655 mrvvhLPGPAGEKGEPGSPgfGLPGKQGKAGERGLKGQKGDAGNPGDPGTP 705
Cdd:NF038329 297 -----LPGKDGKDGQNGKD--GLPGKDGKDGQPGKDGLPGKDGKDGQPGKP 340
|
|
| gly_rich_SclB |
NF038329 |
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ... |
754-935 |
1.37e-11 |
|
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.
Pssm-ID: 468478 [Multi-domain] Cd Length: 440 Bit Score: 67.62 E-value: 1.37e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 754 GPKGEPGPEG-VGHPGKPGQPGLPGVQGPPGPKGTQGEPGPPG-TGAEGPQGEPGTQGLPGTQGLPGPRGPPGSAGEKGA 831
Cdd:NF038329 117 GEKGEPGPAGpAGPAGEQGPRGDRGETGPAGPAGPPGPQGERGeKGPAGPQGEAGPQGPAGKDGEAGAKGPAGEKGPQGP 196
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 832 QGSPGPKGAIGPMGPPGagvsgPPGQKGSRGEKGEPGECSCPSRGEpifsgmpgapglwmgsssqpgpqgpPGVPGPPGP 911
Cdd:NF038329 197 RGETGPAGEQGPAGPAG-----PDGEAGPAGEDGPAGPAGDGQQGP-------------------------DGDPGPTGE 246
|
170 180
....*....|....*....|....
gi 568928185 912 PGMPGLQGVPGHNGLPGQPGLTAE 935
Cdd:NF038329 247 DGPQGPDGPAGKDGPRGDRGEAGP 270
|
|
| SPT5 |
COG5164 |
Transcription elongation factor SPT5 [Transcription]; |
595-855 |
1.29e-09 |
|
Transcription elongation factor SPT5 [Transcription];
Pssm-ID: 444063 [Multi-domain] Cd Length: 495 Bit Score: 61.58 E-value: 1.29e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 595 PGTSGIPGPRGLKGEKGSFGDTGPAGVPGSPGPVGPAGIKGAkgepcepctalselqdgdmrvvhlPGPAGEKGEPGSPG 674
Cdd:COG5164 6 PGKTGPSDPGGVTTPAGSQGSTKPAQNQGSTRPAGNTGGTRP------------------------AQNQGSTTPAGNTG 61
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 675 FGLP-GKQGKAGERGLKGQKGDAGNPGDPGTPGITGQPGISGEPGIRGPAGPKGEKGdgctacpslqGALTDVSGLPGKP 753
Cdd:COG5164 62 GTRPaGNQGATGPAQNQGGTTPAQNQGGTRPAGNTGGTTPAGDGGATGPPDDGGATG----------PPDDGGSTTPPSG 131
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 754 GPKGEPGPEGVGHPGkPGQPGLPGVQGPPGPKGTQGEPGPPGTGAEGPQGEPGTQGLPGTQGLPGPRGPPGSAGEKGAQG 833
Cdd:COG5164 132 GSTTPPGDGGSTPPG-PGSTGPGGSTTPPGDGGSTTPPGPGGSTTPPDDGGSTTPPNKGETGTDIPTGGTPRQGPDGPVK 210
|
250 260
....*....|....*....|..
gi 568928185 834 SPGPKGAIGPmgPPGAGVSGPP 855
Cdd:COG5164 211 KDDKNGKGNP--PDDRGGKTGP 230
|
|
| gly_rich_SclB |
NF038329 |
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ... |
331-541 |
5.07e-08 |
|
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.
Pssm-ID: 468478 [Multi-domain] Cd Length: 440 Bit Score: 56.45 E-value: 5.07e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 331 GPSGLKGGKGERGLTGPSGPKGEKGARGNDCVRVSPDAplqcvEGPKGEKGESGDLGPPGLPGPTGQKGQKGEKGDGGLK 410
Cdd:NF038329 147 GPAGPPGPQGERGEKGPAGPQGEAGPQGPAGKDGEAGA-----KGPAGEKGPQGPRGETGPAGEQGPAGPAGPDGEAGPA 221
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 411 GLPGKPGRDGRP--GEICVIGPKGQKGDPGFVGPEGLAGEPGPPGLPGPPGIGLPGTPGDPGGPPGPKGEKGSSGIPGKE 488
Cdd:NF038329 222 GEDGPAGPAGDGqqGPDGDPGPTGEDGPQGPDGPAGKDGPRGDRGEAGPDGPDGKDGERGPVGPAGKDGQNGKDGLPGKD 301
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 568928185 489 GPGGKPGKPGVPGTKGEKGDPCEvcptlpegsqnfVGLPGKPGPKGEPGDPAP 541
Cdd:NF038329 302 GKDGQNGKDGLPGKDGKDGQPGK------------DGLPGKDGKDGQPGKPAP 342
|
|
| gly_rich_SclB |
NF038329 |
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ... |
799-889 |
8.45e-07 |
|
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.
Pssm-ID: 468478 [Multi-domain] Cd Length: 440 Bit Score: 52.60 E-value: 8.45e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 799 EGPQGEPGTQGLPGTQGLPGPRGPPGSAGEKGAQGSPGPKGAIGPMGPPG----AGVSGPPGQKGSRGEKGEPGECSCP- 873
Cdd:NF038329 116 DGEKGEPGPAGPAGPAGEQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGpqgeAGPQGPAGKDGEAGAKGPAGEKGPQg 195
|
90
....*....|....*.
gi 568928185 874 SRGEPIFSGMPGAPGL 889
Cdd:NF038329 196 PRGETGPAGEQGPAGP 211
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
644-867 |
1.31e-05 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 49.21 E-value: 1.31e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 644 CTALSELQDGDMRVVHLPGPAgekgePGSPGFGLPGKQGKAGERGLKGQKGDAGNPGDPGTPGITGQPGISGEPGIRGPA 723
Cdd:PRK07764 571 VTALAEELGGDWQVEAVVGPA-----PGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAP 645
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 724 GPKGEKGDGctACPSLQGALTDVSGLPGKPGPKGEPGPEGVGHPGKPGQPGlPGVQGPPGPKGTQGEPGPPGTGAEGPQG 803
Cdd:PRK07764 646 GVAAPEHHP--KHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPA-GAAPAQPAPAPAATPPAGQADDPAAQPP 722
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568928185 804 EPGTQGLPGTQGLPGPRGPPGSAGEKGAQGSPGPKGAiGPMGPPGAGVSGPPGQKGSRGEKGEP 867
Cdd:PRK07764 723 QAAQGASAPSPAADDPVPLPPEPDDPPDPAGAPAQPP-PPPAPAPAAAPAAAPPPSPPSEEEEM 785
|
|
| Med15 |
pfam09606 |
ARC105 or Med15 subunit of Mediator complex non-fungal; The approx. 70 residue Med15 domain of ... |
619-869 |
1.05e-04 |
|
ARC105 or Med15 subunit of Mediator complex non-fungal; The approx. 70 residue Med15 domain of the ARC-Mediator co-activator is a three-helix bundle with marked similarity to the KIX domain. The sterol regulatory element binding protein (SREBP) family of transcription activators use the ARC105 subunit to activate target genes in the regulation of cholesterol and fatty acid homeostasis. In addition, Med15 is a critical transducer of gene activation signals that control early metazoan development.
Pssm-ID: 312941 [Multi-domain] Cd Length: 732 Bit Score: 46.15 E-value: 1.05e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 619 AGVPGSP-GPVGPAGIKGAKGEPCEPCTALSELQDGDMRVvhlPGPAGEKGEPGSPgfglpgkqgKAGERGLKGQKGDAG 697
Cdd:pfam09606 57 AAQQQQPqGGQGNGGMGGGQQGMPDPINALQNLAGQGTRP---QMMGPMGPGPGGP---------MGQQMGGPGTASNLL 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 698 NPGDPGTPGITGQPGISGEPGIRGPAGPKGEKGdgctacPSLQGALTDVSGLPGKPGPKGEPGPEGVghPGKPGQPGLPG 777
Cdd:pfam09606 125 ASLGRPQMPMGGAGFPSQMSRVGRMQPGGQAGG------MMQPSSGQPGSGTPNQMGPNGGPGQGQA--GGMNGGQQGPM 196
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 778 VQGPPGPKGTQGEPGPPGTGAEGPQGEPGTQGLPGTQGLPGPRGPPGSAGEKGAQGSPGPKGA-IGPMGPPGAGVSGPPG 856
Cdd:pfam09606 197 GGQMPPQMGVPGMPGPADAGAQMGQQAQANGGMNPQQMGGAPNQVAMQQQQPQQQGQQSQLGMgINQMQQMPQGVGGGAG 276
|
250
....*....|...
gi 568928185 857 QKGSRGEKGEPGE 869
Cdd:pfam09606 277 QGGPGQPMGPPGQ 289
|
|
| Collagen |
pfam01391 |
Collagen triple helix repeat (20 copies); Members of this family belong to the collagen ... |
754-812 |
1.08e-04 |
|
Collagen triple helix repeat (20 copies); Members of this family belong to the collagen superfamily. Collagens are generally extracellular structural proteins involved in formation of connective tissue structure. The alignment contains 20 copies of the G-X-Y repeat that forms a triple helix. The first position of the repeat is glycine, the second and third positions can be any residue but are frequently proline and hydroxy-proline. Collagens are post translationally modified by proline hydroxylase to form the hydroxy-proline residues. Defective hydroxylation is the cause of scurvy. Some members of the collagen superfamily are not involved in connective tissue structure but share the same triple helical structure. The family includes bacterial collagen-like triple-helix repeat proteins.
Pssm-ID: 460189 [Multi-domain] Cd Length: 57 Bit Score: 40.94 E-value: 1.08e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 754 GPKGEPGPegvghPGKPGQPGLPGVQGPPGPKGTQGEPGPPG-TGAEGPQGEPGTQGLPG 812
Cdd:pfam01391 1 GPPGPPGP-----PGPPGPPGPPGPPGPPGPPGPPGEPGPPGpPGPPGPPGPPGAPGAPG 55
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
583-805 |
1.12e-04 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 46.13 E-value: 1.12e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 583 LGPSPGHGLPGLPGTSGIPGPRGLKGEkgsfgdtgPAGVPGSPGPVGPAGIKGAkGEPCEPCTALSELQdgdmrvvhlPG 662
Cdd:PRK07764 588 VGPAPGAAGGEGPPAPASSGPPEEAAR--------PAAPAAPAAPAAPAPAGAA-AAPAEASAAPAPGV---------AA 649
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 663 PAGEKGEPGSPGFGLPGkQGKAGERGLKGQKGDAGNPGDPGTPGITGQPGISGEPgiRGPAGPKGEKGDGCTACP----- 737
Cdd:PRK07764 650 PEHHPKHVAVPDASDGG-DGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAP--APAATPPAGQADDPAAQPpqaaq 726
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568928185 738 ---SLQGALTDVSGLPGKPGPKGEPGPEGVGHPGKPGQPGLPGVQGPPGPKGTQGEPGPPGTGAEGPQGEP 805
Cdd:PRK07764 727 gasAPSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEEEEMAEDDAPSMDDED 797
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
751-869 |
1.15e-04 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 46.13 E-value: 1.15e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 751 GKPGPKGEPGPEGVGHPGKPGQPGLPGVQGPPGPKGTQGEPGPPGTGAEGPQGEPGTQGLPGTQGLPGPRGPPGSAGEKG 830
Cdd:PRK07764 590 PAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGW 669
|
90 100 110
....*....|....*....|....*....|....*....
gi 568928185 831 AQGSPGPKGAIGPMGPPGAGVSGPPGQKGSRGEKGEPGE 869
Cdd:PRK07764 670 PAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAAT 708
|
|
| Collagen |
pfam01391 |
Collagen triple helix repeat (20 copies); Members of this family belong to the collagen ... |
590-643 |
2.57e-04 |
|
Collagen triple helix repeat (20 copies); Members of this family belong to the collagen superfamily. Collagens are generally extracellular structural proteins involved in formation of connective tissue structure. The alignment contains 20 copies of the G-X-Y repeat that forms a triple helix. The first position of the repeat is glycine, the second and third positions can be any residue but are frequently proline and hydroxy-proline. Collagens are post translationally modified by proline hydroxylase to form the hydroxy-proline residues. Defective hydroxylation is the cause of scurvy. Some members of the collagen superfamily are not involved in connective tissue structure but share the same triple helical structure. The family includes bacterial collagen-like triple-helix repeat proteins.
Pssm-ID: 460189 [Multi-domain] Cd Length: 57 Bit Score: 39.78 E-value: 2.57e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 568928185 590 GLPGLPGTSGIPGPRGLKGEKGSFGDTGPAGVPGSPGPVGPAGIKGAKGEPCEP 643
Cdd:pfam01391 1 GPPGPPGPPGPPGPPGPPGPPGPPGPPGPPGEPGPPGPPGPPGPPGPPGAPGAP 54
|
|
| SPT5 |
COG5164 |
Transcription elongation factor SPT5 [Transcription]; |
750-930 |
3.26e-04 |
|
Transcription elongation factor SPT5 [Transcription];
Pssm-ID: 444063 [Multi-domain] Cd Length: 495 Bit Score: 44.25 E-value: 3.26e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 750 PGKPGPKGEPGPEGVGHP-GKPGQPGLPGVQGPPGPKGTQGEPGPPGT-GAEGPQGEPGTQGLPGTQGLPGPRGPPGSAG 827
Cdd:COG5164 3 LYGPGKTGPSDPGGVTTPaGSQGSTKPAQNQGSTRPAGNTGGTRPAQNqGSTTPAGNTGGTRPAGNQGATGPAQNQGGTT 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 828 EKGAQGSPGPKGAIGPMGPPGAGVS-GPPGQKGSRGEKGEPGECSCPSRGEPIFSGMPGAPGLWMGSSSQPGPQGPPGVP 906
Cdd:COG5164 83 PAQNQGGTRPAGNTGGTTPAGDGGAtGPPDDGGATGPPDDGGSTTPPSGGSTTPPGDGGSTPPGPGSTGPGGSTTPPGDG 162
|
170 180
....*....|....*....|....
gi 568928185 907 GPPGPPGMPGLQGVPGHNGLPGQP 930
Cdd:COG5164 163 GSTTPPGPGGSTTPPDDGGSTTPP 186
|
|
| Collagen |
pfam01391 |
Collagen triple helix repeat (20 copies); Members of this family belong to the collagen ... |
584-640 |
3.29e-04 |
|
Collagen triple helix repeat (20 copies); Members of this family belong to the collagen superfamily. Collagens are generally extracellular structural proteins involved in formation of connective tissue structure. The alignment contains 20 copies of the G-X-Y repeat that forms a triple helix. The first position of the repeat is glycine, the second and third positions can be any residue but are frequently proline and hydroxy-proline. Collagens are post translationally modified by proline hydroxylase to form the hydroxy-proline residues. Defective hydroxylation is the cause of scurvy. Some members of the collagen superfamily are not involved in connective tissue structure but share the same triple helical structure. The family includes bacterial collagen-like triple-helix repeat proteins.
Pssm-ID: 460189 [Multi-domain] Cd Length: 57 Bit Score: 39.40 E-value: 3.29e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 568928185 584 GPSPGHGLPGLPGTSGIPGPRGLKGEKGSFGDTGPAGVPGSPGPVGPAGIKGAKGEP 640
Cdd:pfam01391 1 GPPGPPGPPGPPGPPGPPGPPGPPGPPGPPGEPGPPGPPGPPGPPGPPGAPGAPGPP 57
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
713-888 |
3.69e-04 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 44.59 E-value: 3.69e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 713 ISGEPGIRGPAGPKGEKGDGCtacPSLQGALTDVSGLPGKPGPKGEPGPegvGHPGKPGQPGLPGVQGPPGPKGTQGEPG 792
Cdd:PRK07764 588 VGPAPGAAGGEGPPAPASSGP---PEEAARPAAPAAPAAPAAPAPAGAA---AAPAEASAAPAPGVAAPEHHPKHVAVPD 661
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 793 PPGTGAEGPqGEPGTQGLPGTQGLPGPRGPPGSAGEKGAQGSPGPKGAiGPMGPPGAGVSGPPGQKGSRGEKGEPGECSC 872
Cdd:PRK07764 662 ASDGGDGWP-AKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAAT-PPAGQADDPAAQPPQAAQGASAPSPAADDPV 739
|
170
....*....|....*.
gi 568928185 873 PSRGEPIFSGMPGAPG 888
Cdd:PRK07764 740 PLPPEPDDPPDPAGAP 755
|
|
| Collagen |
pfam01391 |
Collagen triple helix repeat (20 copies); Members of this family belong to the collagen ... |
590-643 |
3.78e-04 |
|
Collagen triple helix repeat (20 copies); Members of this family belong to the collagen superfamily. Collagens are generally extracellular structural proteins involved in formation of connective tissue structure. The alignment contains 20 copies of the G-X-Y repeat that forms a triple helix. The first position of the repeat is glycine, the second and third positions can be any residue but are frequently proline and hydroxy-proline. Collagens are post translationally modified by proline hydroxylase to form the hydroxy-proline residues. Defective hydroxylation is the cause of scurvy. Some members of the collagen superfamily are not involved in connective tissue structure but share the same triple helical structure. The family includes bacterial collagen-like triple-helix repeat proteins.
Pssm-ID: 460189 [Multi-domain] Cd Length: 57 Bit Score: 39.40 E-value: 3.78e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 568928185 590 GLPGLPGTSGIPGPRGLKGEKGSFGDTGPAGVPGSPGPVGPAGIKGAKGEPCEP 643
Cdd:pfam01391 4 GPPGPPGPPGPPGPPGPPGPPGPPGPPGEPGPPGPPGPPGPPGPPGAPGAPGPP 57
|
|
| Collagen |
pfam01391 |
Collagen triple helix repeat (20 copies); Members of this family belong to the collagen ... |
660-717 |
3.82e-04 |
|
Collagen triple helix repeat (20 copies); Members of this family belong to the collagen superfamily. Collagens are generally extracellular structural proteins involved in formation of connective tissue structure. The alignment contains 20 copies of the G-X-Y repeat that forms a triple helix. The first position of the repeat is glycine, the second and third positions can be any residue but are frequently proline and hydroxy-proline. Collagens are post translationally modified by proline hydroxylase to form the hydroxy-proline residues. Defective hydroxylation is the cause of scurvy. Some members of the collagen superfamily are not involved in connective tissue structure but share the same triple helical structure. The family includes bacterial collagen-like triple-helix repeat proteins.
Pssm-ID: 460189 [Multi-domain] Cd Length: 57 Bit Score: 39.40 E-value: 3.82e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 568928185 660 LPGPAGEKGEPGSPGFglPGKQGKAGERGLKGQKGDAGNPGDPGTPGITGQPGISGEP 717
Cdd:pfam01391 2 PPGPPGPPGPPGPPGP--PGPPGPPGPPGPPGEPGPPGPPGPPGPPGPPGAPGAPGPP 57
|
|
| Collagen |
pfam01391 |
Collagen triple helix repeat (20 copies); Members of this family belong to the collagen ... |
682-730 |
4.13e-04 |
|
Collagen triple helix repeat (20 copies); Members of this family belong to the collagen superfamily. Collagens are generally extracellular structural proteins involved in formation of connective tissue structure. The alignment contains 20 copies of the G-X-Y repeat that forms a triple helix. The first position of the repeat is glycine, the second and third positions can be any residue but are frequently proline and hydroxy-proline. Collagens are post translationally modified by proline hydroxylase to form the hydroxy-proline residues. Defective hydroxylation is the cause of scurvy. Some members of the collagen superfamily are not involved in connective tissue structure but share the same triple helical structure. The family includes bacterial collagen-like triple-helix repeat proteins.
Pssm-ID: 460189 [Multi-domain] Cd Length: 57 Bit Score: 39.01 E-value: 4.13e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 568928185 682 GKAGERGLKGQKGDAGNPGDPGTPGITGQPGISGEPGIRGPAGPKGEKG 730
Cdd:pfam01391 1 GPPGPPGPPGPPGPPGPPGPPGPPGPPGPPGEPGPPGPPGPPGPPGPPG 49
|
|
| Collagen |
pfam01391 |
Collagen triple helix repeat (20 copies); Members of this family belong to the collagen ... |
676-730 |
4.69e-04 |
|
Collagen triple helix repeat (20 copies); Members of this family belong to the collagen superfamily. Collagens are generally extracellular structural proteins involved in formation of connective tissue structure. The alignment contains 20 copies of the G-X-Y repeat that forms a triple helix. The first position of the repeat is glycine, the second and third positions can be any residue but are frequently proline and hydroxy-proline. Collagens are post translationally modified by proline hydroxylase to form the hydroxy-proline residues. Defective hydroxylation is the cause of scurvy. Some members of the collagen superfamily are not involved in connective tissue structure but share the same triple helical structure. The family includes bacterial collagen-like triple-helix repeat proteins.
Pssm-ID: 460189 [Multi-domain] Cd Length: 57 Bit Score: 39.01 E-value: 4.69e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 568928185 676 GLPGKQGKAGERGLKGQKGDAGNPGDPGTPGITGQPGISGEPGIRGPAGPKGEKG 730
Cdd:pfam01391 1 GPPGPPGPPGPPGPPGPPGPPGPPGPPGPPGEPGPPGPPGPPGPPGPPGAPGAPG 55
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
584-878 |
4.93e-04 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 44.01 E-value: 4.93e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 584 GPSPGHGLPGLPGTSGIPGPrglkgekgsfgdtGPAGVPGSPGP-VGPAGIKGAKGEPCEPCTAlselqDGDMRVVHLPG 662
Cdd:PHA03307 98 ASPAREGSPTPPGPSSPDPP-------------PPTPPPASPPPsPAPDLSEMLRPVGSPGPPP-----AASPPAAGASP 159
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 663 PAGEKGEPGSPGFGLPGKQGKAGERGL-------KGQKGDAGNPGDPGTPGITGQPGiSGEPGIRGPAGPKGEKGDGCTA 735
Cdd:PHA03307 160 AAVASDAASSRQAALPLSSPEETARAPssppaepPPSTPPAAASPRPPRRSSPISAS-ASSPAPAPGRSAADDAGASSSD 238
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 736 CPSLQGALTDVSG-------------LPGKPGPKGEPGPEGVGHPGKPGQPGLPGVQGPPGPKGTQGEPGPPGTGAEGPQ 802
Cdd:PHA03307 239 SSSSESSGCGWGPenecplprpapitLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSS 318
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568928185 803 GEPGTQGLPGTqglpgprgPPGSAGEKGAQGSPGPKGAIGPMGPPGAGVS-GPPGQKGSRGEKGEPGECSCPSRGEP 878
Cdd:PHA03307 319 SSSRESSSSST--------SSSSESSRGAAVSPGPSPSRSPSPSRPPPPAdPSSPRKRPRPSRAPSSPAASAGRPTR 387
|
|
| Collagen |
pfam01391 |
Collagen triple helix repeat (20 copies); Members of this family belong to the collagen ... |
676-728 |
9.34e-04 |
|
Collagen triple helix repeat (20 copies); Members of this family belong to the collagen superfamily. Collagens are generally extracellular structural proteins involved in formation of connective tissue structure. The alignment contains 20 copies of the G-X-Y repeat that forms a triple helix. The first position of the repeat is glycine, the second and third positions can be any residue but are frequently proline and hydroxy-proline. Collagens are post translationally modified by proline hydroxylase to form the hydroxy-proline residues. Defective hydroxylation is the cause of scurvy. Some members of the collagen superfamily are not involved in connective tissue structure but share the same triple helical structure. The family includes bacterial collagen-like triple-helix repeat proteins.
Pssm-ID: 460189 [Multi-domain] Cd Length: 57 Bit Score: 38.24 E-value: 9.34e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 568928185 676 GLPGKQGKAGERGLKGQKGDAGNPGDPGTPGITGQPGISGEPGIRGPAGPKGE 728
Cdd:pfam01391 4 GPPGPPGPPGPPGPPGPPGPPGPPGPPGEPGPPGPPGPPGPPGPPGAPGAPGP 56
|
|
| Collagen |
pfam01391 |
Collagen triple helix repeat (20 copies); Members of this family belong to the collagen ... |
665-723 |
1.00e-03 |
|
Collagen triple helix repeat (20 copies); Members of this family belong to the collagen superfamily. Collagens are generally extracellular structural proteins involved in formation of connective tissue structure. The alignment contains 20 copies of the G-X-Y repeat that forms a triple helix. The first position of the repeat is glycine, the second and third positions can be any residue but are frequently proline and hydroxy-proline. Collagens are post translationally modified by proline hydroxylase to form the hydroxy-proline residues. Defective hydroxylation is the cause of scurvy. Some members of the collagen superfamily are not involved in connective tissue structure but share the same triple helical structure. The family includes bacterial collagen-like triple-helix repeat proteins.
Pssm-ID: 460189 [Multi-domain] Cd Length: 57 Bit Score: 38.24 E-value: 1.00e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 568928185 665 GEKGEPGSPGFglPGKQGKAGERGLKGQKGDAGNPGDPGTPGITGQPGISGEPGIRGPA 723
Cdd:pfam01391 1 GPPGPPGPPGP--PGPPGPPGPPGPPGPPGPPGEPGPPGPPGPPGPPGPPGAPGAPGPP 57
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
618-867 |
2.21e-03 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 42.23 E-value: 2.21e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 618 PAGVPGSPGPVGPAGIKGAK----GEPCEPCTALSELQD-GDMRVVHLPGPAGEKGE--PGSPGFGLPGKQGKAGERGLK 690
Cdd:PHA03247 2713 HALVSATPLPPGPAAARQASpalpAAPAPPAVPAGPATPgGPARPARPPTTAGPPAPapPAAPAAGPPRRLTRPAVASLS 2792
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 691 GQKGDAGNPGDPGTPGITGQPGISGEPGIRGPAGPKgekgdgctacPSLQGALTDVSGLPGKPGPKGEPgPEGVGHPGKP 770
Cdd:PHA03247 2793 ESRESLPSPWDPADPPAAVLAPAAALPPAASPAGPL----------PPPTSAQPTAPPPPPGPPPPSLP-LGGSVAPGGD 2861
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 771 GQPGLPGVQGPPGPKGTqgePGPPGTGAEGPQGEPGTQGLPGTQGLPGPRGPPGSAGEKGAQGSPGPKGAIGPMGPPGAG 850
Cdd:PHA03247 2862 VRRRPPSRSPAAKPAAP---ARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPR 2938
|
250
....*....|....*..
gi 568928185 851 VSGPPGQKGSRGEKGEP 867
Cdd:PHA03247 2939 PQPPLAPTTDPAGAGEP 2955
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
747-930 |
2.40e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 41.90 E-value: 2.40e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 747 SGLPGKPGPKGEPGPEGVGHPGKPGQPGLPGVQGPPGPKGTQGEPGPPGTGAEGPQGEPGTQGLPGTQGLPGPRGPPGSA 826
Cdd:PRK07764 592 PGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPA 671
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 827 GEKGAQGSPGPKGAIGPMGPPGAGVSGPPGQkgSRGEKGEPGECSCPSRGEPIFSGMPGAPGLWMGSSSQPGPQGPPGVP 906
Cdd:PRK07764 672 KAGGAAPAAPPPAPAPAAPAAPAGAAPAQPA--PAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPP 749
|
170 180
....*....|....*....|....
gi 568928185 907 GPPGPPGMPGLQGVPGHNGLPGQP 930
Cdd:PRK07764 750 DPAGAPAQPPPPPAPAPAAAPAAA 773
|
|
| dermokine |
cd21118 |
dermokine; Dermokine, also known as epidermis-specific secreted protein SK30/SK89, is a ... |
671-888 |
5.29e-03 |
|
dermokine; Dermokine, also known as epidermis-specific secreted protein SK30/SK89, is a skin-specific glycoprotein that may play a regulatory role in the crosstalk between barrier dysfunction and inflammation, and therefore play a role in inflammatory diseases such as psoriasis. Dermokine is one of the most highly expressed proteins in differentiating keratinocytes, found mainly in the spinous and granular layers of the epidermis, but also in the epithelia of the small intestine, macrophages of the lung, and endothelial cells of the lung. Mouse dermokine has been reported to be encoded by 22 exons, and its expression leads to alpha, beta, and gamma transcripts.
Pssm-ID: 411053 [Multi-domain] Cd Length: 495 Bit Score: 40.37 E-value: 5.29e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 671 GSPGFGLPGKQGKAGERGlkgqkgdAGNPGDPGTPGITGQP-GISGEPGIRGPAGPKGEKGDGCTAcpslQGAltdvSGL 749
Cdd:cd21118 123 GSGGHGAYGSQGGPGVQG-------HGIPGGTGGPWASGGNyGTNSLGGSVGQGGNGGPLNYGTNS----QGA----VAQ 187
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 750 PGKPGPKGEPGPEGVGHPGKPGQPGLPGVQGPPGPKGTQGEPGPPGTGAEGPQGEPGTQGLPGTQGLPGPRGPPGSAGEK 829
Cdd:cd21118 188 PGYGTVRGNNQNSGCTNPPPSGSHESFSNSGGSSSSGSSGSQGSHGSNGQGSSGSSGGQGNGGNNGSSSSNSGNSGGSNG 267
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 830 GAQG-SPGPKGAIGPMGPPGAGVSGPPGQKGSRGEKGEPgECSCPSRGepifSGMPGAPG 888
Cdd:cd21118 268 GSSGnSGSGSGGSSSGGSNGWGGSSSSGGSGGSGGGNKP-ECNNPGND----VRMAGGGG 322
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
688-855 |
6.93e-03 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 40.54 E-value: 6.93e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 688 GLKGQKGDAGNPGDPGTPGITGQPGISGEPGIRGPAGPKGEKGDGCTACPSLQGALTDVSGLPGKPGPKGEPGPEGVGHP 767
Cdd:PHA03307 38 GSQGQLVSDSAELAAVTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPP 117
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568928185 768 GKPGQPGLPGVQGPPG---PKGTQGEPGPPGTGAEGPQGEPGTQGlPGTQGLPGPRGPPGSAGEKGAQGSPGPKGAIGPM 844
Cdd:PHA03307 118 PPTPPPASPPPSPAPDlseMLRPVGSPGPPPAASPPAAGASPAAV-ASDAASSRQAALPLSSPEETARAPSSPPAEPPPS 196
|
170
....*....|.
gi 568928185 845 GPPGAGVSGPP 855
Cdd:PHA03307 197 TPPAAASPRPP 207
|
|
| |
