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Conserved domains on  [gi|568950765|ref|XP_006507960|]
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nuclear pore complex protein Nup98-Nup96 isoform X3 [Mus musculus]

Protein Classification

Nucleoporin2 and Nup96 domain-containing protein( domain architecture ID 13837547)

Nucleoporin2 and Nup96 domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Nup96 pfam12110
Nuclear protein 96; Nup96 (often known by the name of its yeast homolog Nup145C) is part of ...
 1284-1575 2.26e-131

Nuclear protein 96; Nup96 (often known by the name of its yeast homolog Nup145C) is part of the Nup84 heptameric complex in the nuclear pore complex. Nup96 complexes with Sec13 in the middle of the heptamer. The function of the heptamer is to coat the curvature of the nuclear pore complex between the inner and outer nuclear membranes. Nup96 is predicted to be an alpha helical solenoid. The interaction between Nup96 and Sec13 is the point of curvature in the heptameric complex.


:

Pssm-ID: 463462  Cd Length: 287  Bit Score: 411.22  E-value: 2.26e-131
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  1284 EAVFSYLTGSRISEACCLAQQSGDHRLALLLSQLVGSQSVRELLTMQLADWHQLQADSFIHDERLRIFALLAGKPVWQLS 1363
Cdd:pfam12110    1 EKAFALLTGHRVEEACELAIDSGDFRLATLLSQAGGDDSFREDMAEQLDDWRESGVDSEIDEPRRKLYELLAGNVLVSEG 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  1364 EQKQINVCSQLDWKRTLAIHLWYLLPPTASISRALSMYEEAFQNTPEgdkyACSPLPSYLEGCGCMVEEEKDSRRPLqDV 1443
Cdd:pfam12110   81 KKSTINISEGLDWKRAFGLRLWYGIPPDTSIEDAVEAYEEALSQGRE----PAPPLPWYLEEGDSESWEDPRLKKRE-DL 155

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  1444 CFHLLKLYSDRHYELNQLLEPRSITADPLDYRLSWHLWEVLRA--LNYTHLSEQCEGVLQASYAGQLESEGLWEWAIFVF 1521
Cdd:pfam12110  156 LYHLLKLYADPTAPLEAVLDPESSSPDPLDYRLSWHLYQVLSAvrLGYGHLSSAKADQLTLSFASQLESLGLWQWAVFVL 235

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....
gi 568950765  1522 LHIDNSGMREKAVRELLTRHCQLSETPESwaKEAFLTQKLCVPAEWIHEAKAVR 1575
Cdd:pfam12110  236 LHLEDPARRERAVRELLARHAELISEDDA--KERFLTEKLKIPEAWIHEAKALY 287
Nucleoporin2 pfam04096
Nucleoporin autopeptidase; The nuclear pore complex protein plays a role in bidirectional ...
 691-833 8.71e-64

Nucleoporin autopeptidase; The nuclear pore complex protein plays a role in bidirectional transport across the nucleoporin complex in nucleocytoplasmic transport. The mammalian nuclear pore complex (NPC) is comprised of approximately 30 unique proteins, collectively known as nucleoporins. This family includes yeast family members such as Nup145p as well as vertebrate Nup98. The NUP C-terminal domains of Nup98 and Nup145 possess peptidase S59 autoproteolytic activity. The autoproteolytic sites of Nup98 and Nup145 each occur immediately C-terminal to the NUP C-terminal domain. Thus, although this domain occurs in the middle of each precursor polypeptide, it winds up at the C-terminal end of the N-terminal cleavage product. Cleavage of the peptide chains are necessary for the proper targeting to the nuclear pore.


:

Pssm-ID: 461171  Cd Length: 143  Bit Score: 213.12  E-value: 8.71e-64
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765   691 KVGYYTIPSMDDLAKITnEKGECIVSDFTIGRKGYGSIYFEGDVNLTNLNLDDI----VHIRRKEVIVYVDDNQKPPVGE 766
Cdd:pfam04096    1 KGDYWTSPSLEELKKMS-REQLSSVENFTVGRKGYGSVRFLGPVDLTGLDLDEIfgkiVKFEPREVTVYPDESSKPPVGQ 79

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568950765   767 GLNRKAEVTLDGVWPTDKTSRCLIKSPDRLADINYEGRLEavsRKQGAQFKEYRPETGSWVFKVSHF 833
Cdd:pfam04096   80 GLNVPATITLENVWPRDKDTKEPIKDPSGPRLEKHIERLK---RVQGTEFVSYDPETGTWTFKVEHF 143
Nucleoporin_FG pfam13634
Nucleoporin FG repeat region; This family includes a number of FG repeats that are found in ...
 40-149 2.23e-15

Nucleoporin FG repeat region; This family includes a number of FG repeats that are found in nucleoporin proteins. This family includes the yeast nucleoporins Nup116, Nup100, Nup49, Nup57 and Nup 145.


:

Pssm-ID: 463941 [Multi-domain]  Cd Length: 90  Bit Score: 73.03  E-value: 2.23e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765    40 SAFGSSNNT-GGLFGNSQTKP---GGLFGTSSFSQPATSTSTGFGFGTSTGTSNSLFGTASTGTslfssqnnafaqnkpt 115
Cdd:pfam13634    1 GLFGAATSTsGGLFGNTSTTAasgGGLFGAASTATATTSGGGLFGNSSSNAPSGGLFGATNTTT---------------- 64

                           90       100       110
                   ....*....|....*....|....*....|....
gi 568950765   116 gfgnfgTSTSSGGLFGTTNTTSNPfgSTSGSLFG 149
Cdd:pfam13634   65 ------QTATGGGLFGNNAATTTS--TTGGGLFG 90
Nucleoporin_FG pfam13634
Nucleoporin FG repeat region; This family includes a number of FG repeats that are found in ...
 239-332 9.03e-14

Nucleoporin FG repeat region; This family includes a number of FG repeats that are found in nucleoporin proteins. This family includes the yeast nucleoporins Nup116, Nup100, Nup49, Nup57 and Nup 145.


:

Pssm-ID: 463941 [Multi-domain]  Cd Length: 90  Bit Score: 68.41  E-value: 9.03e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765   239 GLFSSSTTNSAFSYGQNKTAFGTSTTGFGTNpgglfgqQNQQTTSLFSKPFGQATTTPNTGFSFGNTSTLGQPSTNTmGL 318
Cdd:pfam13634    1 GLFGAATSTSGGLFGNTSTTAASGGGLFGAA-------STATATTSGGGLFGNSSSNAPSGGLFGATNTTTQTATGG-GL 72

                           90
                   ....*....|....*...
gi 568950765   319 FGVTQASQP----GGLFG 332
Cdd:pfam13634   73 FGNNAATTTsttgGGLFG 90
FhaB COG3210
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, ...
 24-464 3.79e-12

Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, secretion, and vesicular transport];


:

Pssm-ID: 442443 [Multi-domain]  Cd Length: 1698  Bit Score: 72.11  E-value: 3.79e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765   24 GQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTGFGFGTSTGTSNSLFGTASTGTSLFS 103
Cdd:COG3210   825 TATTGLTGTGDTTSGAGGSNTTDTTTGTTSDGASGGGTAGANSGSLAATAASITVGSGGVATSTGTANAGTLTNLGTTTN 904

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  104 SQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNIS 183
Cdd:COG3210   905 AASGNGAVLATVTATGTGGGGLTGGNAAAGGTGAGNGTTALSGTQGNAGLSAASASDGAGDTGASSAAGSSAVGTSANSA 984

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  184 TKHQCIT-AMKEYESKSLEELRLEDYQANRKGPQNQVGGGTTAGLFGSSPATSSATGLFSSSTTNSAFSYGQNKTAFGTS 262
Cdd:COG3210   985 GSTGGVIaATGILVAGNSGTTASTTGGSGAIVAGGNGVTGTTGTASATGTGTAATAGGQNGVGVNASGISGGNAAALTAS 1064

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  263 TTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTPNTGFSFGNTSTLGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTA 342
Cdd:COG3210  1065 GTAGTTGGTAASNGGGGTAQASGAGTTHTLGGITNGGATGTSGGTTTSTGGVTASKVGGTTTVGATGTSTASTEAAGAGT 1144

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  343 FGTGTGLFGQPNTGFGAVGSTLFGNNKLTTFGTSTTSAPSFGTTSGGLFGNKPTLTLGTNTNTSNFGFGTNNSGSSIFGS 422
Cdd:COG3210  1145 LTGLVAVSAVAGGASSASAGDTTAVAAATTTTTGSAINGGADSAATEGTAGTDLKGGDSTGGSTTTIGTTNVTTTTTLTA 1224

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|..
gi 568950765  423 KPAAGTLGTGLGTGFGTALTDPNASAAQQAVLQQHLNSLTYS 464
Cdd:COG3210  1225 SDTGNTTATGGSSAGQTGSFVAAGSASGTGDATTGATAGAVS 1266
 
Name Accession Description Interval E-value
Nup96 pfam12110
Nuclear protein 96; Nup96 (often known by the name of its yeast homolog Nup145C) is part of ...
 1284-1575 2.26e-131

Nuclear protein 96; Nup96 (often known by the name of its yeast homolog Nup145C) is part of the Nup84 heptameric complex in the nuclear pore complex. Nup96 complexes with Sec13 in the middle of the heptamer. The function of the heptamer is to coat the curvature of the nuclear pore complex between the inner and outer nuclear membranes. Nup96 is predicted to be an alpha helical solenoid. The interaction between Nup96 and Sec13 is the point of curvature in the heptameric complex.


Pssm-ID: 463462  Cd Length: 287  Bit Score: 411.22  E-value: 2.26e-131
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  1284 EAVFSYLTGSRISEACCLAQQSGDHRLALLLSQLVGSQSVRELLTMQLADWHQLQADSFIHDERLRIFALLAGKPVWQLS 1363
Cdd:pfam12110    1 EKAFALLTGHRVEEACELAIDSGDFRLATLLSQAGGDDSFREDMAEQLDDWRESGVDSEIDEPRRKLYELLAGNVLVSEG 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  1364 EQKQINVCSQLDWKRTLAIHLWYLLPPTASISRALSMYEEAFQNTPEgdkyACSPLPSYLEGCGCMVEEEKDSRRPLqDV 1443
Cdd:pfam12110   81 KKSTINISEGLDWKRAFGLRLWYGIPPDTSIEDAVEAYEEALSQGRE----PAPPLPWYLEEGDSESWEDPRLKKRE-DL 155

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  1444 CFHLLKLYSDRHYELNQLLEPRSITADPLDYRLSWHLWEVLRA--LNYTHLSEQCEGVLQASYAGQLESEGLWEWAIFVF 1521
Cdd:pfam12110  156 LYHLLKLYADPTAPLEAVLDPESSSPDPLDYRLSWHLYQVLSAvrLGYGHLSSAKADQLTLSFASQLESLGLWQWAVFVL 235

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....
gi 568950765  1522 LHIDNSGMREKAVRELLTRHCQLSETPESwaKEAFLTQKLCVPAEWIHEAKAVR 1575
Cdd:pfam12110  236 LHLEDPARRERAVRELLARHAELISEDDA--KERFLTEKLKIPEAWIHEAKALY 287
Nucleoporin2 pfam04096
Nucleoporin autopeptidase; The nuclear pore complex protein plays a role in bidirectional ...
 691-833 8.71e-64

Nucleoporin autopeptidase; The nuclear pore complex protein plays a role in bidirectional transport across the nucleoporin complex in nucleocytoplasmic transport. The mammalian nuclear pore complex (NPC) is comprised of approximately 30 unique proteins, collectively known as nucleoporins. This family includes yeast family members such as Nup145p as well as vertebrate Nup98. The NUP C-terminal domains of Nup98 and Nup145 possess peptidase S59 autoproteolytic activity. The autoproteolytic sites of Nup98 and Nup145 each occur immediately C-terminal to the NUP C-terminal domain. Thus, although this domain occurs in the middle of each precursor polypeptide, it winds up at the C-terminal end of the N-terminal cleavage product. Cleavage of the peptide chains are necessary for the proper targeting to the nuclear pore.


Pssm-ID: 461171  Cd Length: 143  Bit Score: 213.12  E-value: 8.71e-64
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765   691 KVGYYTIPSMDDLAKITnEKGECIVSDFTIGRKGYGSIYFEGDVNLTNLNLDDI----VHIRRKEVIVYVDDNQKPPVGE 766
Cdd:pfam04096    1 KGDYWTSPSLEELKKMS-REQLSSVENFTVGRKGYGSVRFLGPVDLTGLDLDEIfgkiVKFEPREVTVYPDESSKPPVGQ 79

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568950765   767 GLNRKAEVTLDGVWPTDKTSRCLIKSPDRLADINYEGRLEavsRKQGAQFKEYRPETGSWVFKVSHF 833
Cdd:pfam04096   80 GLNVPATITLENVWPRDKDTKEPIKDPSGPRLEKHIERLK---RVQGTEFVSYDPETGTWTFKVEHF 143
Nucleoporin_FG pfam13634
Nucleoporin FG repeat region; This family includes a number of FG repeats that are found in ...
 40-149 2.23e-15

Nucleoporin FG repeat region; This family includes a number of FG repeats that are found in nucleoporin proteins. This family includes the yeast nucleoporins Nup116, Nup100, Nup49, Nup57 and Nup 145.


Pssm-ID: 463941 [Multi-domain]  Cd Length: 90  Bit Score: 73.03  E-value: 2.23e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765    40 SAFGSSNNT-GGLFGNSQTKP---GGLFGTSSFSQPATSTSTGFGFGTSTGTSNSLFGTASTGTslfssqnnafaqnkpt 115
Cdd:pfam13634    1 GLFGAATSTsGGLFGNTSTTAasgGGLFGAASTATATTSGGGLFGNSSSNAPSGGLFGATNTTT---------------- 64

                           90       100       110
                   ....*....|....*....|....*....|....
gi 568950765   116 gfgnfgTSTSSGGLFGTTNTTSNPfgSTSGSLFG 149
Cdd:pfam13634   65 ------QTATGGGLFGNNAATTTS--TTGGGLFG 90
Nucleoporin_FG pfam13634
Nucleoporin FG repeat region; This family includes a number of FG repeats that are found in ...
 239-332 9.03e-14

Nucleoporin FG repeat region; This family includes a number of FG repeats that are found in nucleoporin proteins. This family includes the yeast nucleoporins Nup116, Nup100, Nup49, Nup57 and Nup 145.


Pssm-ID: 463941 [Multi-domain]  Cd Length: 90  Bit Score: 68.41  E-value: 9.03e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765   239 GLFSSSTTNSAFSYGQNKTAFGTSTTGFGTNpgglfgqQNQQTTSLFSKPFGQATTTPNTGFSFGNTSTLGQPSTNTmGL 318
Cdd:pfam13634    1 GLFGAATSTSGGLFGNTSTTAASGGGLFGAA-------STATATTSGGGLFGNSSSNAPSGGLFGATNTTTQTATGG-GL 72

                           90
                   ....*....|....*...
gi 568950765   319 FGVTQASQP----GGLFG 332
Cdd:pfam13634   73 FGNNAATTTsttgGGLFG 90
FhaB COG3210
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, ...
 24-464 3.79e-12

Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442443 [Multi-domain]  Cd Length: 1698  Bit Score: 72.11  E-value: 3.79e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765   24 GQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTGFGFGTSTGTSNSLFGTASTGTSLFS 103
Cdd:COG3210   825 TATTGLTGTGDTTSGAGGSNTTDTTTGTTSDGASGGGTAGANSGSLAATAASITVGSGGVATSTGTANAGTLTNLGTTTN 904

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  104 SQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNIS 183
Cdd:COG3210   905 AASGNGAVLATVTATGTGGGGLTGGNAAAGGTGAGNGTTALSGTQGNAGLSAASASDGAGDTGASSAAGSSAVGTSANSA 984

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  184 TKHQCIT-AMKEYESKSLEELRLEDYQANRKGPQNQVGGGTTAGLFGSSPATSSATGLFSSSTTNSAFSYGQNKTAFGTS 262
Cdd:COG3210   985 GSTGGVIaATGILVAGNSGTTASTTGGSGAIVAGGNGVTGTTGTASATGTGTAATAGGQNGVGVNASGISGGNAAALTAS 1064

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  263 TTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTPNTGFSFGNTSTLGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTA 342
Cdd:COG3210  1065 GTAGTTGGTAASNGGGGTAQASGAGTTHTLGGITNGGATGTSGGTTTSTGGVTASKVGGTTTVGATGTSTASTEAAGAGT 1144

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  343 FGTGTGLFGQPNTGFGAVGSTLFGNNKLTTFGTSTTSAPSFGTTSGGLFGNKPTLTLGTNTNTSNFGFGTNNSGSSIFGS 422
Cdd:COG3210  1145 LTGLVAVSAVAGGASSASAGDTTAVAAATTTTTGSAINGGADSAATEGTAGTDLKGGDSTGGSTTTIGTTNVTTTTTLTA 1224

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|..
gi 568950765  423 KPAAGTLGTGLGTGFGTALTDPNASAAQQAVLQQHLNSLTYS 464
Cdd:COG3210  1225 SDTGNTTATGGSSAGQTGSFVAAGSASGTGDATTGATAGAVS 1266
Nucleoporin_FG2 pfam15967
Nucleoporin FG repeated region; Nucleoporin_FG2, or nucleoporin p58/p45, is a family of ...
 44-321 1.84e-11

Nucleoporin FG repeated region; Nucleoporin_FG2, or nucleoporin p58/p45, is a family of chordate nucleoporins. The proteins carry many repeats of the FG sequence motif.


Pssm-ID: 435043 [Multi-domain]  Cd Length: 586  Bit Score: 68.93  E-value: 1.84e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765    44 SSNNTGGLFGNSQTKPGGL-FGTSSFSQPatSTSTGFGFGTSTGTSNSlfgTASTGTSLFSSQNNAFAQNKPTGFGnfgt 122
Cdd:pfam15967    2 SGFSFGGGPGSTATAGGGFsFGAAAASNP--GSTGGFSFGTLGAAPAA---TATTTTATLGLGGGLFGQKPATGFT---- 72

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765   123 stssgglFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNistkhqcitamkeyeskslee 202
Cdd:pfam15967   73 -------FGTPASSTAATGPTGLTLGTPAATTAASTGFSLGFNKPAASATPFSLPASST--------------------- 124

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765   203 lrledyqanrkgpqnqVGGGTTAG--LFGSSPATSSAT---GLFSSSTTNSAFSYGqnkTAFGTSTTGFGtnpGGLFgqQ 277
Cdd:pfam15967  125 ----------------SGGGLSLGsvLTSTAAQQGATGftlNLGGTPATTTAVSTG---LSLGSTLTSLG---GSLF--Q 180

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....
gi 568950765   278 NQQTTSLfskpfGQatTTPNTGFSFGNTSTLGQPSTNtMGLFGV 321
Cdd:pfam15967  181 NTNSTGL-----GQ--TTLGLTLLATSTAPVSAPAAS-EGLGGL 216
ser_rich_anae_1 NF033849
serine-rich protein; This serine-rich protein belongs to a family with large size (over 1000 ...
 25-334 1.54e-10

serine-rich protein; This serine-rich protein belongs to a family with large size (over 1000 amino acids), which a highly serine-rich central region that averages over 300 aa in length. Species encoding members of this family of proteins tend to be anaerobic bacteria, including Gram-positive bacteria of the human gut microbiome and Chloroflexi from marine sediments.


Pssm-ID: 468206 [Multi-domain]  Cd Length: 1122  Bit Score: 66.57  E-value: 1.54e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765   25 QNTGFGTTSGGAFGTS-AFGSSNNTGGLFGNSQTKPGGL---FGTSSFSQPATSTSTGFGFGTSTGTSNSLFGTASTGTS 100
Cdd:NF033849  255 QSHSVGTSESHSVGTSqSQSHTTGHGSTRGWSHTQSTSEsesTGQSSSVGTSESQSHGTTEGTSTTDSSSHSQSSSYNVS 334

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  101 LFSSQNNAFAQNKPTGFGnFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPP--TGTDTMVKAGV 178
Cdd:NF033849  335 SGTGVSSSHSDGTSQSTS-ISHSESSSESTGTSVGHSTSSSVSSSESSSRSSSSGVSGGFSGGIAGGgvTSEGLGASQGG 413

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  179 STNISTKhqcitamkeyesksleelrlEDYQANRKGPQNQVGGGTTAglfGSSPATSSATGLFSSSTTNSAFSYGQNKTA 258
Cdd:NF033849  414 SEGWGSG--------------------DSVQSVSQSYGSSSSTGTSS---GHSDSSSHSTSSGQADSVSQGTSWSEGTGT 470

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568950765  259 fgTSTTGFGTNPGglFGQQNQQTTSlFSKPFGQATTTPN-TGFSFGNTSTLGQPSTNTMGlfgvtQASQPGGLFGTA 334
Cdd:NF033849  471 --SQGQSVGTSES--WSTSQSETDS-VGDSTGTSESVSQgDGRSTGRSESQGTSLGTSGG-----RTSGAGGSMGLG 537
PPE COG5651
PPE-repeat protein [Function unknown];
31-183 1.29e-06

PPE-repeat protein [Function unknown];


Pssm-ID: 444372 [Multi-domain]  Cd Length: 385  Bit Score: 52.59  E-value: 1.29e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765   31 TTSGGAFGTSAFGSSNN-------TGGLFGNSQTKPGGL-FGTSSFSQPATSTSTGFgFGTSTGTSNSLFGTASTGTSLF 102
Cdd:COG5651   175 TNPGGLLGAQNAGSGNTssnpgfaNLGLTGLNQVGIGGLnSGSGPIGLNSGPGNTGF-AGTGAAAGAAAAAAAAAAAAGA 253

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  103 SSQNN-----AFAQNKPTGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAG 177
Cdd:COG5651   254 GASAAlaslaATLLNASSLGLAATAASSAATNLGLAGSPLGLAGGGAGAAAATGLGLGAGGAAGAAGATGAGAALGAGAA 333


                  ....*.
gi 568950765  178 VSTNIS 183
Cdd:COG5651   334 AAAAGA 339
ser_rich_anae_1 NF033849
serine-rich protein; This serine-rich protein belongs to a family with large size (over 1000 ...
 72-392 1.54e-05

serine-rich protein; This serine-rich protein belongs to a family with large size (over 1000 amino acids), which a highly serine-rich central region that averages over 300 aa in length. Species encoding members of this family of proteins tend to be anaerobic bacteria, including Gram-positive bacteria of the human gut microbiome and Chloroflexi from marine sediments.


Pssm-ID: 468206 [Multi-domain]  Cd Length: 1122  Bit Score: 50.00  E-value: 1.54e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765   72 ATSTSTGFGFGTSTGTSNSLfgTASTGTSLFSSQNNAFAQNKPTGFG-NFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGP 150
Cdd:NF033849  236 GQSAGTGYGESVGHSTSQGQ--SHSVGTSESHSVGTSQSQSHTTGHGsTRGWSHTQSTSESESTGQSSSVGTSESQSHGT 313

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  151 SSFTAapTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMKEYESKSLeelrledyqanrkGPQNQVGGGTTAGLFGS 230
Cdd:NF033849  314 TEGTS--TTDSSSHSQSSSYNVSSGTGVSSSHSDGTSQSTSISHSESSSE-------------STGTSVGHSTSSSVSSS 378

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  231 SPATSSATGLFSSSTTNSAFSYGQNKTAFGTS---TTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTPNtGFSFGNTST 307
Cdd:NF033849  379 ESSSRSSSSGVSGGFSGGIAGGGVTSEGLGASqggSEGWGSGDSVQSVSQSYGSSSSTGTSSGHSDSSSH-STSSGQADS 457

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  308 LGQPSTNTMGLfGVTQASQPGGLFGTATNTSTGTAFGTGTglfGQPNTGFGAVGSTLfGNNklTTFGTSTTSAPSFGTTS 387
Cdd:NF033849  458 VSQGTSWSEGT-GTSQGQSVGTSESWSTSQSETDSVGDST---GTSESVSQGDGRST-GRS--ESQGTSLGTSGGRTSGA 530


                  ....*
gi 568950765  388 GGLFG 392
Cdd:NF033849  531 GGSMG 535
auto_AIDA-I NF033176
autotransporter adhesin AIDA-I;
33-389 6.67e-05

autotransporter adhesin AIDA-I;


Pssm-ID: 380183 [Multi-domain]  Cd Length: 1287  Bit Score: 48.12  E-value: 6.67e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765   33 SGGAFGTSAFGSSNNTGGLFGNSQTK-PGGLFGTSSFSQPATS--TSTGFGFGT---STGTSNSLFGTASTGTSLFSSQN 106
Cdd:NF033176  139 SGGAQNIYNLGHASNTVIFNGGNQTIfSGGISDDTNISSGGQQrvSSGGVASNTtinSSGTQNILSGGSTVSTHISSGGN 218

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  107 N-----AFAQNKPTGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAaptGTTIKFNPPTGTDTMVKAGVSTN 181
Cdd:NF033176  219 QyisagGNASATVVSSGGFQRVSSGGTATGTVLSGGTQNVSSGGSAISTSVYSS---GVQTVYAGATVTDTTVNSGGKQN 295

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  182 ISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGGGTTAGLFGSSPATSSATGLFSSSTTNSAFSYGQNKTAFGT 261
Cdd:NF033176  296 ISSGGIVSGTIVNSSGTQNIYSGGSALSANIKGSQIVNSDGTAINTLVNDGGYQHIRNGGVASGTIINQSGRVNISSGGY 375

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  262 STTGFgTNPGGlfgqqnqqTTSLFSKPFGQATTTPNTGFSfgNTSTlGQPSTNTMGLFGVTQASQPGGlfgTATNTSTGT 341
Cdd:NF033176  376 AESTI-INSGG--------TQSVLSGGYASGTLINNSGRE--NVSN-GGSAYNTIINAGGNQYIYSNG---EASGTTVNT 440

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*...
gi 568950765  342 AFgtgtglFGQPNTGFGAVGSTLFGNNKLTTFGTSTTSAPSFgttSGG 389
Cdd:NF033176  441 SG------FQRVNSGGTATGTKLSGGNQNVSSGGKAIAAEVY---SGG 479
34 PHA02584
long tail fiber, proximal subunit; Provisional
 25-263 6.02e-04

long tail fiber, proximal subunit; Provisional


Pssm-ID: 222890 [Multi-domain]  Cd Length: 1229  Bit Score: 44.75  E-value: 6.02e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765   25 QNTGFGTTSGGAFGTSAFGSSNNTGglfgnsqtkpgglfGTSSFSQPATSTSTGF-GFGTSTGTSNSLFGTASTGTSLFS 103
Cdd:PHA02584  944 QNTSNGTVVVVDETSIAFYSQNNTT--------------GNIVFNIDGTVDPINVnANGTLNATGVATNGRAVYAEGGGI 1009

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  104 SQNNAFAQNKPTGFGNF-GTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNI 182
Cdd:PHA02584 1010 ARTNNAARAITGGFTIRnDGSTTVFLLTAAGDQTGGFNGLKSLIINNANGQVTINDNYIINAGGTIMSGGLTVNSRIRSQ 1089

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  183 STKHQCITAMKEyeskslEELRLEDYQANRKGPQNQVGGGTTAGLFGSSPATSSATGlfsssttNSAFSYGQNKTAFGTS 262
Cdd:PHA02584 1090 GTKASYTRAPTA------DTVGFWSVDINDSATYNQFPGYFQMVTKTKSPGTLTQFG-------NTLDSLYQDWSPDGRT 1156


                  .
gi 568950765  263 T 263
Cdd:PHA02584 1157 T 1157
dermokine cd21118
dermokine; Dermokine, also known as epidermis-specific secreted protein SK30/SK89, is a ...
 25-152 1.55e-03

dermokine; Dermokine, also known as epidermis-specific secreted protein SK30/SK89, is a skin-specific glycoprotein that may play a regulatory role in the crosstalk between barrier dysfunction and inflammation, and therefore play a role in inflammatory diseases such as psoriasis. Dermokine is one of the most highly expressed proteins in differentiating keratinocytes, found mainly in the spinous and granular layers of the epidermis, but also in the epithelia of the small intestine, macrophages of the lung, and endothelial cells of the lung. Mouse dermokine has been reported to be encoded by 22 exons, and its expression leads to alpha, beta, and gamma transcripts.


Pssm-ID: 411053 [Multi-domain]  Cd Length: 495  Bit Score: 43.06  E-value: 1.55e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765   25 QNTGFGTTSGGAFGTSAFGSSNNTGGLFG------NSQ--------------------TKPGGLFGTSSFSQPATSTSTG 78
Cdd:cd21118   145 GGTGGPWASGGNYGTNSLGGSVGQGGNGGplnygtNSQgavaqpgygtvrgnnqnsgcTNPPPSGSHESFSNSGGSSSSG 224

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568950765   79 FGFGTSTGTSNSLFGTASTGTSLFSSQNNAFAQNK-PTGFGNFGTSTSSGGLFG-TTNTTSNPFGSTSGSLFGPSS 152
Cdd:cd21118   225 SSGSQGSHGSNGQGSSGSSGGQGNGGNNGSSSSNSgNSGGSNGGSSGNSGSGSGgSSSGGSNGWGGSSSSGGSGGS 300
PTZ00473 PTZ00473
Plasmodium Vir superfamily; Provisional
 26-100 2.92e-03

Plasmodium Vir superfamily; Provisional


Pssm-ID: 240430 [Multi-domain]  Cd Length: 420  Bit Score: 42.14  E-value: 2.92e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765   26 NTGFGTTSGGAF--------------GTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTGFgFGTSTGTSNSL 91
Cdd:PTZ00473  315 RGPYNANYGGQFnsrsgrtgssesirGFTYDSSTTYGGSSYGTSQTDSTSTYGSRSTFDSSTGGGSQS-GGGSTYGGSST 393


                  ....*....
gi 568950765   92 FGTASTGTS 100
Cdd:PTZ00473  394 FDGSSRGSS 402
 
Name Accession Description Interval E-value
Nup96 pfam12110
Nuclear protein 96; Nup96 (often known by the name of its yeast homolog Nup145C) is part of ...
 1284-1575 2.26e-131

Nuclear protein 96; Nup96 (often known by the name of its yeast homolog Nup145C) is part of the Nup84 heptameric complex in the nuclear pore complex. Nup96 complexes with Sec13 in the middle of the heptamer. The function of the heptamer is to coat the curvature of the nuclear pore complex between the inner and outer nuclear membranes. Nup96 is predicted to be an alpha helical solenoid. The interaction between Nup96 and Sec13 is the point of curvature in the heptameric complex.


Pssm-ID: 463462  Cd Length: 287  Bit Score: 411.22  E-value: 2.26e-131
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  1284 EAVFSYLTGSRISEACCLAQQSGDHRLALLLSQLVGSQSVRELLTMQLADWHQLQADSFIHDERLRIFALLAGKPVWQLS 1363
Cdd:pfam12110    1 EKAFALLTGHRVEEACELAIDSGDFRLATLLSQAGGDDSFREDMAEQLDDWRESGVDSEIDEPRRKLYELLAGNVLVSEG 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  1364 EQKQINVCSQLDWKRTLAIHLWYLLPPTASISRALSMYEEAFQNTPEgdkyACSPLPSYLEGCGCMVEEEKDSRRPLqDV 1443
Cdd:pfam12110   81 KKSTINISEGLDWKRAFGLRLWYGIPPDTSIEDAVEAYEEALSQGRE----PAPPLPWYLEEGDSESWEDPRLKKRE-DL 155

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  1444 CFHLLKLYSDRHYELNQLLEPRSITADPLDYRLSWHLWEVLRA--LNYTHLSEQCEGVLQASYAGQLESEGLWEWAIFVF 1521
Cdd:pfam12110  156 LYHLLKLYADPTAPLEAVLDPESSSPDPLDYRLSWHLYQVLSAvrLGYGHLSSAKADQLTLSFASQLESLGLWQWAVFVL 235

                          250       260       270       280       290
                   ....*....|....*....|....*....|....*....|....*....|....
gi 568950765  1522 LHIDNSGMREKAVRELLTRHCQLSETPESwaKEAFLTQKLCVPAEWIHEAKAVR 1575
Cdd:pfam12110  236 LHLEDPARRERAVRELLARHAELISEDDA--KERFLTEKLKIPEAWIHEAKALY 287
Nucleoporin2 pfam04096
Nucleoporin autopeptidase; The nuclear pore complex protein plays a role in bidirectional ...
 691-833 8.71e-64

Nucleoporin autopeptidase; The nuclear pore complex protein plays a role in bidirectional transport across the nucleoporin complex in nucleocytoplasmic transport. The mammalian nuclear pore complex (NPC) is comprised of approximately 30 unique proteins, collectively known as nucleoporins. This family includes yeast family members such as Nup145p as well as vertebrate Nup98. The NUP C-terminal domains of Nup98 and Nup145 possess peptidase S59 autoproteolytic activity. The autoproteolytic sites of Nup98 and Nup145 each occur immediately C-terminal to the NUP C-terminal domain. Thus, although this domain occurs in the middle of each precursor polypeptide, it winds up at the C-terminal end of the N-terminal cleavage product. Cleavage of the peptide chains are necessary for the proper targeting to the nuclear pore.


Pssm-ID: 461171  Cd Length: 143  Bit Score: 213.12  E-value: 8.71e-64
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765   691 KVGYYTIPSMDDLAKITnEKGECIVSDFTIGRKGYGSIYFEGDVNLTNLNLDDI----VHIRRKEVIVYVDDNQKPPVGE 766
Cdd:pfam04096    1 KGDYWTSPSLEELKKMS-REQLSSVENFTVGRKGYGSVRFLGPVDLTGLDLDEIfgkiVKFEPREVTVYPDESSKPPVGQ 79

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568950765   767 GLNRKAEVTLDGVWPTDKTSRCLIKSPDRLADINYEGRLEavsRKQGAQFKEYRPETGSWVFKVSHF 833
Cdd:pfam04096   80 GLNVPATITLENVWPRDKDTKEPIKDPSGPRLEKHIERLK---RVQGTEFVSYDPETGTWTFKVEHF 143
Nucleoporin_FG pfam13634
Nucleoporin FG repeat region; This family includes a number of FG repeats that are found in ...
 40-149 2.23e-15

Nucleoporin FG repeat region; This family includes a number of FG repeats that are found in nucleoporin proteins. This family includes the yeast nucleoporins Nup116, Nup100, Nup49, Nup57 and Nup 145.


Pssm-ID: 463941 [Multi-domain]  Cd Length: 90  Bit Score: 73.03  E-value: 2.23e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765    40 SAFGSSNNT-GGLFGNSQTKP---GGLFGTSSFSQPATSTSTGFGFGTSTGTSNSLFGTASTGTslfssqnnafaqnkpt 115
Cdd:pfam13634    1 GLFGAATSTsGGLFGNTSTTAasgGGLFGAASTATATTSGGGLFGNSSSNAPSGGLFGATNTTT---------------- 64

                           90       100       110
                   ....*....|....*....|....*....|....
gi 568950765   116 gfgnfgTSTSSGGLFGTTNTTSNPfgSTSGSLFG 149
Cdd:pfam13634   65 ------QTATGGGLFGNNAATTTS--TTGGGLFG 90
Nucleoporin_FG pfam13634
Nucleoporin FG repeat region; This family includes a number of FG repeats that are found in ...
 239-332 9.03e-14

Nucleoporin FG repeat region; This family includes a number of FG repeats that are found in nucleoporin proteins. This family includes the yeast nucleoporins Nup116, Nup100, Nup49, Nup57 and Nup 145.


Pssm-ID: 463941 [Multi-domain]  Cd Length: 90  Bit Score: 68.41  E-value: 9.03e-14
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765   239 GLFSSSTTNSAFSYGQNKTAFGTSTTGFGTNpgglfgqQNQQTTSLFSKPFGQATTTPNTGFSFGNTSTLGQPSTNTmGL 318
Cdd:pfam13634    1 GLFGAATSTSGGLFGNTSTTAASGGGLFGAA-------STATATTSGGGLFGNSSSNAPSGGLFGATNTTTQTATGG-GL 72

                           90
                   ....*....|....*...
gi 568950765   319 FGVTQASQP----GGLFG 332
Cdd:pfam13634   73 FGNNAATTTsttgGGLFG 90
Nucleoporin_FG pfam13634
Nucleoporin FG repeat region; This family includes a number of FG repeats that are found in ...
 272-392 1.15e-12

Nucleoporin FG repeat region; This family includes a number of FG repeats that are found in nucleoporin proteins. This family includes the yeast nucleoporins Nup116, Nup100, Nup49, Nup57 and Nup 145.


Pssm-ID: 463941 [Multi-domain]  Cd Length: 90  Bit Score: 65.33  E-value: 1.15e-12
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765   272 GLFGQQNQQTTSLFSkpfGQATTTPNTGFSFGNTSTlGQPSTNTMGLFGVTQASQP-GGLFGTATntstgtafgtgtglf 350
Cdd:pfam13634    1 GLFGAATSTSGGLFG---NTSTTAASGGGLFGAAST-ATATTSGGGLFGNSSSNAPsGGLFGATN--------------- 61

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|..
gi 568950765   351 gqpNTGFGAVGSTLFGNNklttfgtsttSAPSFGTTSGGLFG 392
Cdd:pfam13634   62 ---TTTQTATGGGLFGNN----------AATTTSTTGGGLFG 90
FhaB COG3210
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, ...
 24-464 3.79e-12

Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442443 [Multi-domain]  Cd Length: 1698  Bit Score: 72.11  E-value: 3.79e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765   24 GQNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTGFGFGTSTGTSNSLFGTASTGTSLFS 103
Cdd:COG3210   825 TATTGLTGTGDTTSGAGGSNTTDTTTGTTSDGASGGGTAGANSGSLAATAASITVGSGGVATSTGTANAGTLTNLGTTTN 904

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  104 SQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNIS 183
Cdd:COG3210   905 AASGNGAVLATVTATGTGGGGLTGGNAAAGGTGAGNGTTALSGTQGNAGLSAASASDGAGDTGASSAAGSSAVGTSANSA 984

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  184 TKHQCIT-AMKEYESKSLEELRLEDYQANRKGPQNQVGGGTTAGLFGSSPATSSATGLFSSSTTNSAFSYGQNKTAFGTS 262
Cdd:COG3210   985 GSTGGVIaATGILVAGNSGTTASTTGGSGAIVAGGNGVTGTTGTASATGTGTAATAGGQNGVGVNASGISGGNAAALTAS 1064

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  263 TTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTPNTGFSFGNTSTLGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTA 342
Cdd:COG3210  1065 GTAGTTGGTAASNGGGGTAQASGAGTTHTLGGITNGGATGTSGGTTTSTGGVTASKVGGTTTVGATGTSTASTEAAGAGT 1144

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  343 FGTGTGLFGQPNTGFGAVGSTLFGNNKLTTFGTSTTSAPSFGTTSGGLFGNKPTLTLGTNTNTSNFGFGTNNSGSSIFGS 422
Cdd:COG3210  1145 LTGLVAVSAVAGGASSASAGDTTAVAAATTTTTGSAINGGADSAATEGTAGTDLKGGDSTGGSTTTIGTTNVTTTTTLTA 1224

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|..
gi 568950765  423 KPAAGTLGTGLGTGFGTALTDPNASAAQQAVLQQHLNSLTYS 464
Cdd:COG3210  1225 SDTGNTTATGGSSAGQTGSFVAAGSASGTGDATTGATAGAVS 1266
Nucleoporin_FG2 pfam15967
Nucleoporin FG repeated region; Nucleoporin_FG2, or nucleoporin p58/p45, is a family of ...
 44-321 1.84e-11

Nucleoporin FG repeated region; Nucleoporin_FG2, or nucleoporin p58/p45, is a family of chordate nucleoporins. The proteins carry many repeats of the FG sequence motif.


Pssm-ID: 435043 [Multi-domain]  Cd Length: 586  Bit Score: 68.93  E-value: 1.84e-11
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765    44 SSNNTGGLFGNSQTKPGGL-FGTSSFSQPatSTSTGFGFGTSTGTSNSlfgTASTGTSLFSSQNNAFAQNKPTGFGnfgt 122
Cdd:pfam15967    2 SGFSFGGGPGSTATAGGGFsFGAAAASNP--GSTGGFSFGTLGAAPAA---TATTTTATLGLGGGLFGQKPATGFT---- 72

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765   123 stssgglFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNistkhqcitamkeyeskslee 202
Cdd:pfam15967   73 -------FGTPASSTAATGPTGLTLGTPAATTAASTGFSLGFNKPAASATPFSLPASST--------------------- 124

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765   203 lrledyqanrkgpqnqVGGGTTAG--LFGSSPATSSAT---GLFSSSTTNSAFSYGqnkTAFGTSTTGFGtnpGGLFgqQ 277
Cdd:pfam15967  125 ----------------SGGGLSLGsvLTSTAAQQGATGftlNLGGTPATTTAVSTG---LSLGSTLTSLG---GSLF--Q 180

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|....
gi 568950765   278 NQQTTSLfskpfGQatTTPNTGFSFGNTSTLGQPSTNtMGLFGV 321
Cdd:pfam15967  181 NTNSTGL-----GQ--TTLGLTLLATSTAPVSAPAAS-EGLGGL 216
FhaB COG3210
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, ...
 25-419 8.34e-11

Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442443 [Multi-domain]  Cd Length: 1698  Bit Score: 67.48  E-value: 8.34e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765   25 QNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTGFGFGTSTGTSNSLFGTASTGTSLFSS 104
Cdd:COG3210   368 NGGGLTTAGAGTVASTVGTATASTGNASSTTVLGSGSLATGNTGTTIAGNGGSANAGGFTTTGGVLGITGNGTVTGGTIG 447

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  105 QNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNIST 184
Cdd:COG3210   448 GLTGSGTTNGAGLSGNTDVSGTGTVTNSAGNTTSATTLAGGGIGTVTTNATISNNAGGDANGIATGLTGITAGGGGGGNA 527

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  185 KhqcitamkeyesksleelrledyqanrkGPQNQVGGGTTAGLFGSSPATSSATGLFSSSTTNSAFSYGQNKTAFGTSTT 264
Cdd:COG3210   528 T----------------------------SGGTGGDGTTLSGSGLTTTVSGGASGTTAASGSNTANTLGVLAATGGTSNA 579

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  265 GFGTNPGGLFGQQNQQTTSLFSKPFGQATTTPNTGFSFGNTSTLGQPSTNTmGLFGVTQASQPGGLFGTATNTSTGTAFG 344
Cdd:COG3210   580 TTAGNSTSATGGTGTNSGGTVLSIGTGSAGATGTITLGAGTSGAGANATGG-GAGLTGSAVGAALSGTGSGTTGTASANG 658

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568950765  345 TGTGLFGQPNTGFGAVGSTLFGNNKLTTFGTSTTSAPSFGTTSGGlfgNKPTLTLGTNTNTSNFGFGTNNSGSSI 419
Cdd:COG3210   659 SNTTGVNTAGGTGGGTTGTVTSGATGGTTGTTLNAATGGTLNNAG---NTLTISTGSITVTGQIGALANANGDTV 730
ser_rich_anae_1 NF033849
serine-rich protein; This serine-rich protein belongs to a family with large size (over 1000 ...
 25-334 1.54e-10

serine-rich protein; This serine-rich protein belongs to a family with large size (over 1000 amino acids), which a highly serine-rich central region that averages over 300 aa in length. Species encoding members of this family of proteins tend to be anaerobic bacteria, including Gram-positive bacteria of the human gut microbiome and Chloroflexi from marine sediments.


Pssm-ID: 468206 [Multi-domain]  Cd Length: 1122  Bit Score: 66.57  E-value: 1.54e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765   25 QNTGFGTTSGGAFGTS-AFGSSNNTGGLFGNSQTKPGGL---FGTSSFSQPATSTSTGFGFGTSTGTSNSLFGTASTGTS 100
Cdd:NF033849  255 QSHSVGTSESHSVGTSqSQSHTTGHGSTRGWSHTQSTSEsesTGQSSSVGTSESQSHGTTEGTSTTDSSSHSQSSSYNVS 334

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  101 LFSSQNNAFAQNKPTGFGnFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPP--TGTDTMVKAGV 178
Cdd:NF033849  335 SGTGVSSSHSDGTSQSTS-ISHSESSSESTGTSVGHSTSSSVSSSESSSRSSSSGVSGGFSGGIAGGgvTSEGLGASQGG 413

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  179 STNISTKhqcitamkeyesksleelrlEDYQANRKGPQNQVGGGTTAglfGSSPATSSATGLFSSSTTNSAFSYGQNKTA 258
Cdd:NF033849  414 SEGWGSG--------------------DSVQSVSQSYGSSSSTGTSS---GHSDSSSHSTSSGQADSVSQGTSWSEGTGT 470

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568950765  259 fgTSTTGFGTNPGglFGQQNQQTTSlFSKPFGQATTTPN-TGFSFGNTSTLGQPSTNTMGlfgvtQASQPGGLFGTA 334
Cdd:NF033849  471 --SQGQSVGTSES--WSTSQSETDS-VGDSTGTSESVSQgDGRSTGRSESQGTSLGTSGG-----RTSGAGGSMGLG 537
FhaB COG3210
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, ...
 26-422 6.57e-10

Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442443 [Multi-domain]  Cd Length: 1698  Bit Score: 64.40  E-value: 6.57e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765   26 NTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTGFGFGTSTGTSNSLFGTASTGTSLFSSQ 105
Cdd:COG3210   616 LGAGTSGAGANATGGGAGLTGSAVGAALSGTGSGTTGTASANGSNTTGVNTAGGTGGGTTGTVTSGATGGTTGTTLNAAT 695

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  106 NNAFAQNKPTGFGNFGTSTSSGGL------FGTTNTTSNPFGSTS--------------GSLFGPSSFTAAPTGTTIKFN 165
Cdd:COG3210   696 GGTLNNAGNTLTISTGSITVTGQIgalanaNGDTVTFGNLGTGATltlnagvtitsgnaGTLSIGLTANTTASGTTLTLA 775

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  166 PPTGTDTmVKAGVSTNISTKHQCITAmkeyesksleelrleDYQANRKGPqNQVGGGTTAGLFGSSPATSSATGLFSSST 245
Cdd:COG3210   776 NANGNTS-AGATLDNAGAEISIDITA---------------DGTITAAGT-TAINVTGSGGTITINTATTGLTGTGDTTS 838

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  246 TNSAFSYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTPNTGFSFGNTSTLGQPSTNTMGLFGVTQAS 325
Cdd:COG3210   839 GAGGSNTTDTTTGTTSDGASGGGTAGANSGSLAATAASITVGSGGVATSTGTANAGTLTNLGTTTNAASGNGAVLATVTA 918

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  326 QPGGLFGTATNTSTGTAFGTGTGLFGQPNTGFGAVGSTLFGNNKLTTFGTSTTSAPSFGTTSGGLFGNKPTLTLGTNTNT 405
Cdd:COG3210   919 TGTGGGGLTGGNAAAGGTGAGNGTTALSGTQGNAGLSAASASDGAGDTGASSAAGSSAVGTSANSAGSTGGVIAATGILV 998

                         410
                  ....*....|....*..
gi 568950765  406 SNFGFGTNNSGSSIFGS 422
Cdd:COG3210   999 AGNSGTTASTTGGSGAI 1015
Nucleoporin_FG pfam13634
Nucleoporin FG repeat region; This family includes a number of FG repeats that are found in ...
 25-93 4.75e-09

Nucleoporin FG repeat region; This family includes a number of FG repeats that are found in nucleoporin proteins. This family includes the yeast nucleoporins Nup116, Nup100, Nup49, Nup57 and Nup 145.


Pssm-ID: 463941 [Multi-domain]  Cd Length: 90  Bit Score: 54.93  E-value: 4.75e-09
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568950765    25 QNTGFGTTSGGAFGTSAFGSSNNTGG-LFGNSQTKP--GGLFGTSSFSQPATSTSTGFGFGTSTGTSN---SLFG 93
Cdd:pfam13634   16 NTSTTAASGGGLFGAASTATATTSGGgLFGNSSSNApsGGLFGATNTTTQTATGGGLFGNNAATTTSTtggGLFG 90
FhaB COG3210
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, ...
 25-422 6.07e-09

Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442443 [Multi-domain]  Cd Length: 1698  Bit Score: 61.32  E-value: 6.07e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765   25 QNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTGFGFGTSTGTSNSLFGTASTGTSLFSS 104
Cdd:COG3210   466 VSGTGTVTNSAGNTTSATTLAGGGIGTVTTNATISNNAGGDANGIATGLTGITAGGGGGGNATSGGTGGDGTTLSGSGLT 545

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  105 QNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNIST 184
Cdd:COG3210   546 TTVSGGASGTTAASGSNTANTLGVLAATGGTSNATTAGNSTSATGGTGTNSGGTVLSIGTGSAGATGTITLGAGTSGAGA 625

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  185 KHQCITAmkeyesksleelrledyqaNRKGPQNQVGGGTTAGLFGSSPATSSATGLFSSSTTNSAFSYGQNKTAFGTSTT 264
Cdd:COG3210   626 NATGGGA-------------------GLTGSAVGAALSGTGSGTTGTASANGSNTTGVNTAGGTGGGTTGTVTSGATGGT 686

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  265 GFGTNPGGLFGQQNQQTTSLF--------SKPFGQATTTPNTGFSFGNTSTLGQPSTNTmglfGVTQASqpgGLFGTATN 336
Cdd:COG3210   687 TGTTLNAATGGTLNNAGNTLTistgsitvTGQIGALANANGDTVTFGNLGTGATLTLNA----GVTITS---GNAGTLSI 759

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  337 TSTGTAFGTGTGLFGQPNTGFGAVGSTLFGN-NKLTTFGTSTTSAPSFGTTSGGLFGNKPTLTLGTNTNTSNFGFGTNNS 415
Cdd:COG3210   760 GLTANTTASGTTLTLANANGNTSAGATLDNAgAEISIDITADGTITAAGTTAINVTGSGGTITINTATTGLTGTGDTTSG 839


                  ....*..
gi 568950765  416 GSSIFGS 422
Cdd:COG3210   840 AGGSNTT 846
Nucleoporin_FG pfam13634
Nucleoporin FG repeat region; This family includes a number of FG repeats that are found in ...
 90-161 6.56e-09

Nucleoporin FG repeat region; This family includes a number of FG repeats that are found in nucleoporin proteins. This family includes the yeast nucleoporins Nup116, Nup100, Nup49, Nup57 and Nup 145.


Pssm-ID: 463941 [Multi-domain]  Cd Length: 90  Bit Score: 54.54  E-value: 6.56e-09
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765    90 SLFGTA-STGTSLFSSQNNAF------------AQNKPTGFGNFG---TSTSSGGLFGTTNTTSNPfgSTSGSLFGPSSF 153
Cdd:pfam13634    1 GLFGAAtSTSGGLFGNTSTTAasggglfgaastATATTSGGGLFGnssSNAPSGGLFGATNTTTQT--ATGGGLFGNNAA 78


                   ....*...
gi 568950765   154 TAAPTGTT 161
Cdd:pfam13634   79 TTTSTTGG 86
FhaB COG3210
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, ...
 26-419 1.07e-08

Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442443 [Multi-domain]  Cd Length: 1698  Bit Score: 60.55  E-value: 1.07e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765   26 NTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTGFGFGTSTGTSNSLFGTASTGTSLFSSQ 105
Cdd:COG3210   585 STSATGGTGTNSGGTVLSIGTGSAGATGTITLGAGTSGAGANATGGGAGLTGSAVGAALSGTGSGTTGTASANGSNTTGV 664

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  106 NNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLF-GPSSFTAA--------PTGTTIKF-NPPTGTDTMVK 175
Cdd:COG3210   665 NTAGGTGGGTTGTVTSGATGGTTGTTLNAATGGTLNNAGNTLTiSTGSITVTgqigalanANGDTVTFgNLGTGATLTLN 744

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  176 AGVSTNISTKHQCITAMKEYESKSLEELRLedyqanrkgpqNQVGGGTTAGLFG-------SSPATSSATGLFSSSTTNS 248
Cdd:COG3210   745 AGVTITSGNAGTLSIGLTANTTASGTTLTL-----------ANANGNTSAGATLdnagaeiSIDITADGTITAAGTTAIN 813

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  249 AFSYGQNKTAFGTSTTGFGTNPGGLFGQQNQQTTSLFSkpfGQATTTPNTGFSFGNTSTLGQPSTNTMGLFGVTQASQPG 328
Cdd:COG3210   814 VTGSGGTITINTATTGLTGTGDTTSGAGGSNTTDTTTG---TTSDGASGGGTAGANSGSLAATAASITVGSGGVATSTGT 890

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  329 GLFGTATNTSTGTAFGTGTGLFGQPNTGFGAVGSTLFGNNKLTTFGTSTTSAPSFGTTSGGLFGNKPTLTLGTNTNTSNF 408
Cdd:COG3210   891 ANAGTLTNLGTTTNAASGNGAVLATVTATGTGGGGLTGGNAAAGGTGAGNGTTALSGTQGNAGLSAASASDGAGDTGASS 970

                         410
                  ....*....|.
gi 568950765  409 GFGTNNSGSSI 419
Cdd:COG3210   971 AAGSSAVGTSA 981
FhaB COG3210
Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, ...
 25-422 1.71e-08

Large exoprotein involved in heme utilization or adhesion [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442443 [Multi-domain]  Cd Length: 1698  Bit Score: 59.78  E-value: 1.71e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765   25 QNTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTGFGFGTSTGTSNSLFGTASTGTSLFSS 104
Cdd:COG3210   788 DNAGAEISIDITADGTITAAGTTAINVTGSGGTITINTATTGLTGTGDTTSGAGGSNTTDTTTGTTSDGASGGGTAGANS 867

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  105 QNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIkfnppTGTDTMVKAGVSTNIST 184
Cdd:COG3210   868 GSLAATAASITVGSGGVATSTGTANAGTLTNLGTTTNAASGNGAVLATVTATGTGGGG-----LTGGNAAAGGTGAGNGT 942

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  185 KHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGGGTTAGLFGSSPATSSATGLFSSSTTNSAFSYGQNKTAFGTSTT 264
Cdd:COG3210   943 TALSGTQGNAGLSAASASDGAGDTGASSAAGSSAVGTSANSAGSTGGVIAATGILVAGNSGTTASTTGGSGAIVAGGNGV 1022

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  265 GFGTNPGGLFGQQNQQTTSLFSkpfGQATTTPNTGFSFGNTSTLGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFG 344
Cdd:COG3210  1023 TGTTGTASATGTGTAATAGGQN---GVGVNASGISGGNAAALTASGTAGTTGGTAASNGGGGTAQASGAGTTHTLGGITN 1099

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568950765  345 TGTGLFGQPNTGFGAVGSTLFGNNKLTTFGTSTTSAPSFGTTSGGLFGNKPTLTLGTNTNTSNFGFGTNNSGSSIFGS 422
Cdd:COG3210  1100 GGATGTSGGTTTSTGGVTASKVGGTTTVGATGTSTASTEAAGAGTLTGLVAVSAVAGGASSASAGDTTAVAAATTTTT 1177
COG4625 COG4625
Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain [Function ...
 26-391 4.64e-08

Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain [Function unknown];


Pssm-ID: 443664 [Multi-domain]  Cd Length: 900  Bit Score: 58.25  E-value: 4.64e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765   26 NTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTGFGFGTSTGTSNSLFGTASTGTSLFSSQ 105
Cdd:COG4625   123 GGGAGGAGGGGGGGAGGGGGGGGGGGAGGGGGGGAGGAGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGNGGGGGGGGG 202

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  106 NNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTK 185
Cdd:COG4625   203 GGGGGGGGGGGAGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGAGGGGGGGGGNGGGGGAGGGGGGGGGGSGGGGGGG 282

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  186 HQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGGGTTAGLFGSSPATSSATGLFSSSTTNSAFSYGQNKTAFGTSTTG 265
Cdd:COG4625   283 GGGGSGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGAGGGGGSGGAGAGGGGAGGGGAGGGGGGG 362

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  266 FGTNPGGLFGQQNQQTTSLFSKPFGQATTTPNTGfsfgNTSTLGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGT 345
Cdd:COG4625   363 TGGGGGGGGGGGGGSGGGGAGGGGGSGGGGGGGA----GGGGGGGGAGGTGGGGAGGGGGAAGGGGGGTGAGGGGGGGGT 438

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*.
gi 568950765  346 GTGLFGQPNTGFGAVGSTLFGNNKLTTFGTSTTSAPSFGTTSGGLF 391
Cdd:COG4625   439 GAGGGGATGGGGGGGGGAGGSGGGAGAGGGSGSGAGTLTLTGNNTY 484
AidA COG3468
Autotransporter adhesin AidA [Cell wall/membrane/envelope biogenesis, Intracellular ...
 26-388 6.00e-07

Autotransporter adhesin AidA [Cell wall/membrane/envelope biogenesis, Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 442691 [Multi-domain]  Cd Length: 846  Bit Score: 54.57  E-value: 6.00e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765   26 NTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTGFGFGTSTGTSNSLFGTASTGTSLF--- 102
Cdd:COG3468   100 GTGGGGGGGGSGNGGGGGGGGGGGGTGGGGGGGTGSAGGGGGGGGGGTGVGGTGAAAAGGGTGSGGGGSGGGGGAGGggg 179

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  103 -----SSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAG 177
Cdd:COG3468   180 ggaggSGGAGSTGSGAGGGGGGSGGGGGAAGTGGGGGGGGGAGGATGGAGSGGNTGGGVGGGGGSAGGTGGGGLTGGGAA 259

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  178 VSTNISTKHqcitamkeyesksleelrleDYQANRKGPQNQVGGGTTAGLFGSSPATSSATGLFSSSTTNSAFSYGQNKT 257
Cdd:COG3468   260 GTGGGGGGT--------------------GTGSGGGGGGGANGGGSGGGGGASGTGGGGTASTGGGGGGGGGNGGGGGGG 319

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  258 AFGTSTTGFGTNPGGLFGQQNQQTTSLFSKPFGQATT---TPNTGFSFGNTSTLGQPSTNTMGLFGVTQASQPGGLFGTA 334
Cdd:COG3468   320 SNAGGGSGGGGGGGGGGGGGGTTLNGAGSAGGGTGAAlagTGGSGSGGGGGGGSGGGGGAGGGGANTGSDGVGTGLTTGG 399

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 568950765  335 TNTSTGTAFGTGTGLFGQPNTGFGAVGSTLFGNNKLTTFGT--STTSAPS-----FGTTSG 388
Cdd:COG3468   400 TGNNGGGGVGGGGGGGLTLTGGTLTVNGNYTGNNGTLVLNTvlGDDNSPTdrlvvNGNTSG 460
Nucleoporin_FG pfam13634
Nucleoporin FG repeat region; This family includes a number of FG repeats that are found in ...
 115-275 1.09e-06

Nucleoporin FG repeat region; This family includes a number of FG repeats that are found in nucleoporin proteins. This family includes the yeast nucleoporins Nup116, Nup100, Nup49, Nup57 and Nup 145.


Pssm-ID: 463941 [Multi-domain]  Cd Length: 90  Bit Score: 48.38  E-value: 1.09e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765   115 TGFGNfgTSTSSGGLFGTTNTTsnpfGSTSGSLFGPSSFTAAPTgttikfnpptgtdtmvkagvstnistkhqcitamke 194
Cdd:pfam13634    1 GLFGA--ATSTSGGLFGNTSTT----AASGGGLFGAASTATATT------------------------------------ 38

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765   195 yesksleelrledyqanrkgpqnqvgggTTAGLFGSSPATSSATGLFSSSTTNSAFSygQNKTAFG-TSTTGFGTNPGGL 273
Cdd:pfam13634   39 ----------------------------SGGGLFGNSSSNAPSGGLFGATNTTTQTA--TGGGLFGnNAATTTSTTGGGL 88


                   ..
gi 568950765   274 FG 275
Cdd:pfam13634   89 FG 90
Nucleoporin_FG pfam13634
Nucleoporin FG repeat region; This family includes a number of FG repeats that are found in ...
 216-320 1.16e-06

Nucleoporin FG repeat region; This family includes a number of FG repeats that are found in nucleoporin proteins. This family includes the yeast nucleoporins Nup116, Nup100, Nup49, Nup57 and Nup 145.


Pssm-ID: 463941 [Multi-domain]  Cd Length: 90  Bit Score: 48.38  E-value: 1.16e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765   216 QNQVGGGTTAGLFGSSPATSSATGLFSSsttnsafsygqnktaFGTSTTgfGTNPGGLFGQQNQQttslfskpfgqaTTT 295
Cdd:pfam13634   16 NTSTTAASGGGLFGAASTATATTSGGGL---------------FGNSSS--NAPSGGLFGATNTT------------TQT 66

                           90       100
                   ....*....|....*....|....*
gi 568950765   296 PNTGFSFGNTSTLGQPSTNTmGLFG 320
Cdd:pfam13634   67 ATGGGLFGNNAATTTSTTGG-GLFG 90
PPE COG5651
PPE-repeat protein [Function unknown];
31-183 1.29e-06

PPE-repeat protein [Function unknown];


Pssm-ID: 444372 [Multi-domain]  Cd Length: 385  Bit Score: 52.59  E-value: 1.29e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765   31 TTSGGAFGTSAFGSSNN-------TGGLFGNSQTKPGGL-FGTSSFSQPATSTSTGFgFGTSTGTSNSLFGTASTGTSLF 102
Cdd:COG5651   175 TNPGGLLGAQNAGSGNTssnpgfaNLGLTGLNQVGIGGLnSGSGPIGLNSGPGNTGF-AGTGAAAGAAAAAAAAAAAAGA 253

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  103 SSQNN-----AFAQNKPTGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAG 177
Cdd:COG5651   254 GASAAlaslaATLLNASSLGLAATAASSAATNLGLAGSPLGLAGGGAGAAAATGLGLGAGGAAGAAGATGAGAALGAGAA 333


                  ....*.
gi 568950765  178 VSTNIS 183
Cdd:COG5651   334 AAAAGA 339
Nucleoporin_FG2 pfam15967
Nucleoporin FG repeated region; Nucleoporin_FG2, or nucleoporin p58/p45, is a family of ...
 28-262 1.88e-06

Nucleoporin FG repeated region; Nucleoporin_FG2, or nucleoporin p58/p45, is a family of chordate nucleoporins. The proteins carry many repeats of the FG sequence motif.


Pssm-ID: 435043 [Multi-domain]  Cd Length: 586  Bit Score: 52.75  E-value: 1.88e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765    28 GFGTTSGG--AFGTSAFGSSNNTGGL-FGNSQTKP--------------GGLFGtssfSQPATststGFGFGT------S 84
Cdd:pfam15967   11 GSTATAGGgfSFGAAAASNPGSTGGFsFGTLGAAPaatattttatlglgGGLFG----QKPAT----GFTFGTpasstaA 82

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765    85 TGTSNSLFGTASTGTSlfSSQNNAFAQNKPTG----FGNFGTSTSSGGL-FGTTNTTSNPFGSTSGSLFG----PSSFTA 155
Cdd:pfam15967   83 TGPTGLTLGTPAATTA--ASTGFSLGFNKPAAsatpFSLPASSTSGGGLsLGSVLTSTAAQQGATGFTLNlggtPATTTA 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765   156 APTGTTIKFNPPTGTDTMVKAGVSTNIStkhqcitamkeyesksleelrledyqanrkgpQNQVGGGTTAGLFGSSPATS 235
Cdd:pfam15967  161 VSTGLSLGSTLTSLGGSLFQNTNSTGLG--------------------------------QTTLGLTLLATSTAPVSAPA 208

                          250       260       270
                   ....*....|....*....|....*....|.
gi 568950765   236 SATGL----FSSSTTNsafsygQNKTAFGTS 262
Cdd:pfam15967  209 ASEGLggldFSTSSEK------KSDKASGTR 233
Hia COG5295
Autotransporter adhesin [Intracellular trafficking, secretion, and vesicular transport, ...
 26-419 7.07e-06

Autotransporter adhesin [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444098 [Multi-domain]  Cd Length: 785  Bit Score: 50.92  E-value: 7.07e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765   26 NTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTGFGFGTSTGTSNSLFGTASTGTSLFSSQ 105
Cdd:COG5295   239 ASAGAASGNATTASASSVSGSAVAAGTASTATTASTTAASGAAGTATAAAGGDAAAAGSASSTGAANATAGGGNAGSGGG 318

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  106 NNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNISTK 185
Cdd:COG5295   319 GAAALGSAGGSSGVGTASGASAAAATNDGTANGAGTSAAADATSGGGAGGGGAAATSSSGGSATAAGNAAGAAGAGSAGS 398

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  186 hqcITAMKEYESKSLEELrledYQANRKGPQNQVGGGTTAGLFGSSPATSSATGLFSSSTTNSAFSYGQNKTAFGTSTTG 265
Cdd:COG5295   399 ---GGSSTGASAGGGASA----AGGAAAGSAAAGTSSNTSAVGASNGASGTSSSASSAGAAGGGTAGAGGAANVGAATTA 471

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  266 FGTNPGGLFGQQNQQTTSLFSKPFGQATTTPNTGFSFGNTSTLGQPSTNTMGLFGVTQASQPGGLFGTATNTSTGTAFGT 345
Cdd:COG5295   472 ASAAATAAAATSSAAIAGATATGAGAAAGGAGAGAAGGAGSAAAGGAANAAAASGATATAGSAGGGAAAAAGGGSTTAAT 551

                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568950765  346 GtglfgqpnTGFGAVGSTLFGNNKLTTFGTSTTsAPSFGTTSGGLFGNKPTLTLGTNTNTSNFGFGTNNSGSSI 419
Cdd:COG5295   552 G--------TNSVAVGNNTATGANSVALGAGSV-ASGANSVSVGAAGAENVAAGATDTDAVNGGGAVATGDNSV 616
ser_rich_anae_1 NF033849
serine-rich protein; This serine-rich protein belongs to a family with large size (over 1000 ...
 72-392 1.54e-05

serine-rich protein; This serine-rich protein belongs to a family with large size (over 1000 amino acids), which a highly serine-rich central region that averages over 300 aa in length. Species encoding members of this family of proteins tend to be anaerobic bacteria, including Gram-positive bacteria of the human gut microbiome and Chloroflexi from marine sediments.


Pssm-ID: 468206 [Multi-domain]  Cd Length: 1122  Bit Score: 50.00  E-value: 1.54e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765   72 ATSTSTGFGFGTSTGTSNSLfgTASTGTSLFSSQNNAFAQNKPTGFG-NFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGP 150
Cdd:NF033849  236 GQSAGTGYGESVGHSTSQGQ--SHSVGTSESHSVGTSQSQSHTTGHGsTRGWSHTQSTSESESTGQSSSVGTSESQSHGT 313

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  151 SSFTAapTGTTIKFNPPTGTDTMVKAGVSTNISTKHQCITAMKEYESKSLeelrledyqanrkGPQNQVGGGTTAGLFGS 230
Cdd:NF033849  314 TEGTS--TTDSSSHSQSSSYNVSSGTGVSSSHSDGTSQSTSISHSESSSE-------------STGTSVGHSTSSSVSSS 378

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  231 SPATSSATGLFSSSTTNSAFSYGQNKTAFGTS---TTGFGTNPGGLFGQQNQQTTSLFSKPFGQATTTPNtGFSFGNTST 307
Cdd:NF033849  379 ESSSRSSSSGVSGGFSGGIAGGGVTSEGLGASqggSEGWGSGDSVQSVSQSYGSSSSTGTSSGHSDSSSH-STSSGQADS 457

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  308 LGQPSTNTMGLfGVTQASQPGGLFGTATNTSTGTAFGTGTglfGQPNTGFGAVGSTLfGNNklTTFGTSTTSAPSFGTTS 387
Cdd:NF033849  458 VSQGTSWSEGT-GTSQGQSVGTSESWSTSQSETDSVGDST---GTSESVSQGDGRST-GRS--ESQGTSLGTSGGRTSGA 530


                  ....*
gi 568950765  388 GGLFG 392
Cdd:NF033849  531 GGSMG 535
Chi1 COG3469
Chitinase [Carbohydrate transport and metabolism];
26-172 2.32e-05

Chitinase [Carbohydrate transport and metabolism];


Pssm-ID: 442692 [Multi-domain]  Cd Length: 534  Bit Score: 48.98  E-value: 2.32e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765   26 NTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTGFGFGTST----------GTSNSLFGTA 95
Cdd:COG3469    52 AASGSAGSGTGTTAASSTAATSSTTSTTATATAAAAAATSTSATLVATSTASGANTGTSTvtttstgagsVTSTTSSTAG 131

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568950765   96 STGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGlfgTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDT 172
Cdd:COG3469   132 STTTSGASATSSAGSTTTTTTVSGTETATGGTT---TTSTTTTTTSASTTPSATTTATATTASGATTPSATTTATTT 205
auto_AIDA-I NF033176
autotransporter adhesin AIDA-I;
33-389 6.67e-05

autotransporter adhesin AIDA-I;


Pssm-ID: 380183 [Multi-domain]  Cd Length: 1287  Bit Score: 48.12  E-value: 6.67e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765   33 SGGAFGTSAFGSSNNTGGLFGNSQTK-PGGLFGTSSFSQPATS--TSTGFGFGT---STGTSNSLFGTASTGTSLFSSQN 106
Cdd:NF033176  139 SGGAQNIYNLGHASNTVIFNGGNQTIfSGGISDDTNISSGGQQrvSSGGVASNTtinSSGTQNILSGGSTVSTHISSGGN 218

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  107 N-----AFAQNKPTGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAaptGTTIKFNPPTGTDTMVKAGVSTN 181
Cdd:NF033176  219 QyisagGNASATVVSSGGFQRVSSGGTATGTVLSGGTQNVSSGGSAISTSVYSS---GVQTVYAGATVTDTTVNSGGKQN 295

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  182 ISTKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGGGTTAGLFGSSPATSSATGLFSSSTTNSAFSYGQNKTAFGT 261
Cdd:NF033176  296 ISSGGIVSGTIVNSSGTQNIYSGGSALSANIKGSQIVNSDGTAINTLVNDGGYQHIRNGGVASGTIINQSGRVNISSGGY 375

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  262 STTGFgTNPGGlfgqqnqqTTSLFSKPFGQATTTPNTGFSfgNTSTlGQPSTNTMGLFGVTQASQPGGlfgTATNTSTGT 341
Cdd:NF033176  376 AESTI-INSGG--------TQSVLSGGYASGTLINNSGRE--NVSN-GGSAYNTIINAGGNQYIYSNG---EASGTTVNT 440

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*...
gi 568950765  342 AFgtgtglFGQPNTGFGAVGSTLFGNNKLTTFGTSTTSAPSFgttSGG 389
Cdd:NF033176  441 SG------FQRVNSGGTATGTKLSGGNQNVSSGGKAIAAEVY---SGG 479
Chi1 COG3469
Chitinase [Carbohydrate transport and metabolism];
26-167 8.44e-05

Chitinase [Carbohydrate transport and metabolism];


Pssm-ID: 442692 [Multi-domain]  Cd Length: 534  Bit Score: 47.44  E-value: 8.44e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765   26 NTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTGFGFGTSTGTSNSLFGTASTGTSLFSSQ 105
Cdd:COG3469    75 TTSTTATATAAAAAATSTSATLVATSTASGANTGTSTVTTTSTGAGSVTSTTSSTAGSTTTSGASATSSAGSTTTTTTVS 154

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 568950765  106 NNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSNpfgSTSGSLFGPSSFTAAPTGTTIKFNPP 167
Cdd:COG3469   155 GTETATGGTTTTSTTTTTTSASTTPSATTTATA---TTASGATTPSATTTATTTGPPTPGLP 213
COG4625 COG4625
Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain [Function ...
 26-334 3.72e-04

Uncharacterized conserved protein, contains a C-terminal beta-barrel porin domain [Function unknown];


Pssm-ID: 443664 [Multi-domain]  Cd Length: 900  Bit Score: 45.54  E-value: 3.72e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765   26 NTGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTGFGFGTSTGTSNSLFGTASTGTSLFSSQ 105
Cdd:COG4625   369 GGGGGGGGSGGGGAGGGGGSGGGGGGGAGGGGGGGGAGGTGGGGAGGGGGAAGGGGGGTGAGGGGGGGGTGAGGGGATGG 448

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  106 NNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAG-VSTNIST 184
Cdd:COG4625   449 GGGGGGGAGGSGGGAGAGGGSGSGAGTLTLTGNNTYTGTTTVNGGGNYTQSAGSTLAVEVDAANSDRLVVTGtATLNGGT 528

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  185 KHQCITAMKEYESKSLEEL--RLEDYQANRKGPQ--NQVGGGTTAGLfgsSPATSSATGLFSSSTTNSAF--SYGQNKTA 258
Cdd:COG4625   529 VVVLAGGYAPGTTYTILAVaaALDALAGNGDLSAlyNALAALDAAAA---RAALDQLSGEIHASAAAALLqaSRALRDAL 605

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568950765  259 FGTSTTGFGTnpgGLFGQQNQQTTSLFSKPFGQ-ATTTPNTGFSFGNTSTLGqpstntmGLFGVTQASQPGGLFGTA 334
Cdd:COG4625   606 SNRLRALRGA---GAAGDAAAEGWGVWAQGFGSwGDQDGDGGAAGYDSSTGG-------LLVGADYRLGDNWRLGVA 672
34 PHA02584
long tail fiber, proximal subunit; Provisional
 25-263 6.02e-04

long tail fiber, proximal subunit; Provisional


Pssm-ID: 222890 [Multi-domain]  Cd Length: 1229  Bit Score: 44.75  E-value: 6.02e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765   25 QNTGFGTTSGGAFGTSAFGSSNNTGglfgnsqtkpgglfGTSSFSQPATSTSTGF-GFGTSTGTSNSLFGTASTGTSLFS 103
Cdd:PHA02584  944 QNTSNGTVVVVDETSIAFYSQNNTT--------------GNIVFNIDGTVDPINVnANGTLNATGVATNGRAVYAEGGGI 1009

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  104 SQNNAFAQNKPTGFGNF-GTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNI 182
Cdd:PHA02584 1010 ARTNNAARAITGGFTIRnDGSTTVFLLTAAGDQTGGFNGLKSLIINNANGQVTINDNYIINAGGTIMSGGLTVNSRIRSQ 1089

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  183 STKHQCITAMKEyeskslEELRLEDYQANRKGPQNQVGGGTTAGLFGSSPATSSATGlfsssttNSAFSYGQNKTAFGTS 262
Cdd:PHA02584 1090 GTKASYTRAPTA------DTVGFWSVDINDSATYNQFPGYFQMVTKTKSPGTLTQFG-------NTLDSLYQDWSPDGRT 1156


                  .
gi 568950765  263 T 263
Cdd:PHA02584 1157 T 1157
Nucleoporin_FG2 pfam15967
Nucleoporin FG repeated region; Nucleoporin_FG2, or nucleoporin p58/p45, is a family of ...
 228-497 6.64e-04

Nucleoporin FG repeated region; Nucleoporin_FG2, or nucleoporin p58/p45, is a family of chordate nucleoporins. The proteins carry many repeats of the FG sequence motif.


Pssm-ID: 435043 [Multi-domain]  Cd Length: 586  Bit Score: 44.27  E-value: 6.64e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765   228 FGSSPATSSATGlfsssttnSAFSYGQNKTAFGTSTTG--FGTNPGGLFGQQNQQTTS--LFSKPFGQattTPNTGFSFG 303
Cdd:pfam15967    6 FGGGPGSTATAG--------GGFSFGAAAASNPGSTGGfsFGTLGAAPAATATTTTATlgLGGGLFGQ---KPATGFTFG 74

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765   304 NTST---LGQPSTNTMGLFGVTQASQPGGLFGtatntstgtafgtgtglFGQPN---TGFGAVGSTLFGNNklTTFGTS- 376
Cdd:pfam15967   75 TPASstaATGPTGLTLGTPAATTAASTGFSLG-----------------FNKPAasaTPFSLPASSTSGGG--LSLGSVl 135

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765   377 TTSAPSFGTTSGGL-FGNKPTLTLGTNTNTSnFGFGTNNSGSSIFGSKPAAGTLGTGLGTGFGTALTDPNAsaaqQAVLQ 455
Cdd:pfam15967  136 TSTAAQQGATGFTLnLGGTPATTTAVSTGLS-LGSTLTSLGGSLFQNTNSTGLGQTTLGLTLLATSTAPVS----APAAS 210

                          250       260       270       280
                   ....*....|....*....|....*....|....*....|..
gi 568950765   456 QHLNSLTYSpfgdsplfrnpmSDPKKKEERLKPTNPAAQKAL 497
Cdd:pfam15967  211 EGLGGLDFS------------TSSEKKSDKASGTRPEDSKAL 240
Hia COG5295
Autotransporter adhesin [Intracellular trafficking, secretion, and vesicular transport, ...
 27-269 8.95e-04

Autotransporter adhesin [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444098 [Multi-domain]  Cd Length: 785  Bit Score: 43.99  E-value: 8.95e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765   27 TGFGTTSGGAFGTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTGFGFGTSTGTSNSLFGTASTGTSLFSSQN 106
Cdd:COG5295   382 TAAGNAAGAAGAGSAGSGGSSTGASAGGGASAAGGAAAGSAAAGTSSNTSAVGASNGASGTSSSASSAGAAGGGTAGAGG 461

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  107 NAFAQNKPTGFGN---FGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGTDTMVKAGVSTNIS 183
Cdd:COG5295   462 AANVGAATTAASAaatAAAATSSAAIAGATATGAGAAAGGAGAGAAGGAGSAAAGGAANAAAASGATATAGSAGGGAAAA 541

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765  184 TKHQCITAMKEYESKSLEELRLEDYQANRKGPQNQVGG---------GTTAGLFGSSP------ATSSATGLFSSSTTNS 248
Cdd:COG5295   542 AGGGSTTAATGTNSVAVGNNTATGANSVALGAGSVASGansvsvgaaGAENVAAGATDtdavngGGAVATGDNSVAVGNN 621

                         250       260
                  ....*....|....*....|.
gi 568950765  249 AFSYGQNKTAFGTSTTGFGTN 269
Cdd:COG5295   622 AQASGANSVALGAGATATANN 642
dermokine cd21118
dermokine; Dermokine, also known as epidermis-specific secreted protein SK30/SK89, is a ...
 25-152 1.55e-03

dermokine; Dermokine, also known as epidermis-specific secreted protein SK30/SK89, is a skin-specific glycoprotein that may play a regulatory role in the crosstalk between barrier dysfunction and inflammation, and therefore play a role in inflammatory diseases such as psoriasis. Dermokine is one of the most highly expressed proteins in differentiating keratinocytes, found mainly in the spinous and granular layers of the epidermis, but also in the epithelia of the small intestine, macrophages of the lung, and endothelial cells of the lung. Mouse dermokine has been reported to be encoded by 22 exons, and its expression leads to alpha, beta, and gamma transcripts.


Pssm-ID: 411053 [Multi-domain]  Cd Length: 495  Bit Score: 43.06  E-value: 1.55e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765   25 QNTGFGTTSGGAFGTSAFGSSNNTGGLFG------NSQ--------------------TKPGGLFGTSSFSQPATSTSTG 78
Cdd:cd21118   145 GGTGGPWASGGNYGTNSLGGSVGQGGNGGplnygtNSQgavaqpgygtvrgnnqnsgcTNPPPSGSHESFSNSGGSSSSG 224

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568950765   79 FGFGTSTGTSNSLFGTASTGTSLFSSQNNAFAQNK-PTGFGNFGTSTSSGGLFG-TTNTTSNPFGSTSGSLFGPSS 152
Cdd:cd21118   225 SSGSQGSHGSNGQGSSGSSGGQGNGGNNGSSSSNSgNSGGSNGGSSGNSGSGSGgSSSGGSNGWGGSSSSGGSGGS 300
PTZ00473 PTZ00473
Plasmodium Vir superfamily; Provisional
 26-100 2.92e-03

Plasmodium Vir superfamily; Provisional


Pssm-ID: 240430 [Multi-domain]  Cd Length: 420  Bit Score: 42.14  E-value: 2.92e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765   26 NTGFGTTSGGAF--------------GTSAFGSSNNTGGLFGNSQTKPGGLFGTSSFSQPATSTSTGFgFGTSTGTSNSL 91
Cdd:PTZ00473  315 RGPYNANYGGQFnsrsgrtgssesirGFTYDSSTTYGGSSYGTSQTDSTSTYGSRSTFDSSTGGGSQS-GGGSTYGGSST 393


                  ....*....
gi 568950765   92 FGTASTGTS 100
Cdd:PTZ00473  394 FDGSSRGSS 402
PPE COG5651
PPE-repeat protein [Function unknown];
26-159 4.90e-03

PPE-repeat protein [Function unknown];


Pssm-ID: 444372 [Multi-domain]  Cd Length: 385  Bit Score: 41.42  E-value: 4.90e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765   26 NTGFGTTSGGAFGTSAFGSSNN-TGGLFGNSQTKPGGLFGTS---SFSQPATSTSTGFGFGTST---------GTSNSLF 92
Cdd:COG5651   194 NPGFANLGLTGLNQVGIGGLNSgSGPIGLNSGPGNTGFAGTGaaaGAAAAAAAAAAAAGAGASAalaslaatlLNASSLG 273

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568950765   93 GTASTGTSLFSSQNNAFAQNKPTGFGNFGTSTSSGGLFGTTNTTSNPFGSTSGSLFGPSSFTAAPTG 159
Cdd:COG5651   274 LAATAASSAATNLGLAGSPLGLAGGGAGAAAATGLGLGAGGAAGAAGATGAGAALGAGAAAAAAGAA 340
Nucleoporin_FG2 pfam15967
Nucleoporin FG repeated region; Nucleoporin_FG2, or nucleoporin p58/p45, is a family of ...
 222-390 5.59e-03

Nucleoporin FG repeated region; Nucleoporin_FG2, or nucleoporin p58/p45, is a family of chordate nucleoporins. The proteins carry many repeats of the FG sequence motif.


Pssm-ID: 435043 [Multi-domain]  Cd Length: 586  Bit Score: 41.58  E-value: 5.59e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765   222 GTTAGLFGSSPATSSATGLFSSSTTNSAFS--YGQNKTAFGTSTTGFGtnpgglFGqqnqqttslFSKPFGQAT------ 293
Cdd:pfam15967   57 GLGGGLFGQKPATGFTFGTPASSTAATGPTglTLGTPAATTAASTGFS------LG---------FNKPAASATpfslpa 121

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568950765   294 -TTPNTGFSFGNTSTLGQP----STNTMGLFGVTQASQPG--GLFGTATntstgtAFGTGTGLFGQPNT---GFGAVGST 363
Cdd:pfam15967  122 sSTSGGGLSLGSVLTSTAAqqgaTGFTLNLGGTPATTTAVstGLSLGST------LTSLGGSLFQNTNStglGQTTLGLT 195

                          170       180
                   ....*....|....*....|....*..
gi 568950765   364 LFGNNklttfgTSTTSAPSFGTTSGGL 390
Cdd:pfam15967  196 LLATS------TAPVSAPAASEGLGGL 216
PTZ00473 PTZ00473
Plasmodium Vir superfamily; Provisional
 28-100 8.64e-03

Plasmodium Vir superfamily; Provisional


Pssm-ID: 240430 [Multi-domain]  Cd Length: 420  Bit Score: 40.60  E-value: 8.64e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568950765   28 GFGTTSGGAFGTSAFGSSNNTGG-LFGNSQTKPGGLFGTSSFSQpATSTSTGFGFGTSTGTSNSLFGTASTGTS 100
Cdd:PTZ00473  341 GFTYDSSTTYGGSSYGTSQTDSTsTYGSRSTFDSSTGGGSQSGG-GSTYGGSSTFDGSSRGSSDSFGVSYFGPQ 413
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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