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Conserved domains on  [gi|568965788|ref|XP_006512979|]
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solute carrier family 35 member D3 isoform X1 [Mus musculus]

Protein Classification

nucleotide-sugar transporter family protein( domain architecture ID 706892)

nucleotide-sugar transporter family protein may mediate the transport of nucleotides or sugars or their derivatives; belongs to the drug/metabolite transporter (DMT) superfamily

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
UAA super family cl26745
UAA transporter family; This family includes transporters with a specificity for ...
 19-152 3.67e-04

UAA transporter family; This family includes transporters with a specificity for UDP-N-acetylglucosamine.


The actual alignment was detected with superfamily member pfam08449:

Pssm-ID: 462479 [Multi-domain]  Cd Length: 307  Bit Score: 41.51  E-value: 3.67e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568965788   19 GVFSG--SLNILLKFLISRYQFS---FLTLVQCLTSSTAALSLELLRRLGLIAVPPfGLSLaRSFAGVAVLSTLQSSLTL 93
Cdd:pfam08449   8 GVFGGccSNGVLQELIMKVEPGPfgnLLTFAQFLFYALEGLPESIDIFTSKFLKPR-KIPL-KTYVILVALFFITSVLNN 85

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 568965788   94 WSLR-GLSLPMYVVFKRCLPLVTMLIGVLVLKNGAPSPGVLAAVLITTcGAALAAPSSGG 152
Cdd:pfam08449  86 EALKyDISYPTHIIFRSSKLIPVMIMGILILGKRYSKLQYLSAFLVTL-GIIIFTLFSAK 144
 
Name Accession Description Interval E-value
UAA pfam08449
UAA transporter family; This family includes transporters with a specificity for ...
 19-152 3.67e-04

UAA transporter family; This family includes transporters with a specificity for UDP-N-acetylglucosamine.


Pssm-ID: 462479 [Multi-domain]  Cd Length: 307  Bit Score: 41.51  E-value: 3.67e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568965788   19 GVFSG--SLNILLKFLISRYQFS---FLTLVQCLTSSTAALSLELLRRLGLIAVPPfGLSLaRSFAGVAVLSTLQSSLTL 93
Cdd:pfam08449   8 GVFGGccSNGVLQELIMKVEPGPfgnLLTFAQFLFYALEGLPESIDIFTSKFLKPR-KIPL-KTYVILVALFFITSVLNN 85

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 568965788   94 WSLR-GLSLPMYVVFKRCLPLVTMLIGVLVLKNGAPSPGVLAAVLITTcGAALAAPSSGG 152
Cdd:pfam08449  86 EALKyDISYPTHIIFRSSKLIPVMIMGILILGKRYSKLQYLSAFLVTL-GIIIFTLFSAK 144
 
Name Accession Description Interval E-value
UAA pfam08449
UAA transporter family; This family includes transporters with a specificity for ...
 19-152 3.67e-04

UAA transporter family; This family includes transporters with a specificity for UDP-N-acetylglucosamine.


Pssm-ID: 462479 [Multi-domain]  Cd Length: 307  Bit Score: 41.51  E-value: 3.67e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568965788   19 GVFSG--SLNILLKFLISRYQFS---FLTLVQCLTSSTAALSLELLRRLGLIAVPPfGLSLaRSFAGVAVLSTLQSSLTL 93
Cdd:pfam08449   8 GVFGGccSNGVLQELIMKVEPGPfgnLLTFAQFLFYALEGLPESIDIFTSKFLKPR-KIPL-KTYVILVALFFITSVLNN 85

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 568965788   94 WSLR-GLSLPMYVVFKRCLPLVTMLIGVLVLKNGAPSPGVLAAVLITTcGAALAAPSSGG 152
Cdd:pfam08449  86 EALKyDISYPTHIIFRSSKLIPVMIMGILILGKRYSKLQYLSAFLVTL-GIIIFTLFSAK 144
EamA pfam00892
EamA-like transporter family; This family includes many hypothetical membrane proteins of ...
 10-138 4.16e-03

EamA-like transporter family; This family includes many hypothetical membrane proteins of unknown function. Many of the proteins contain two copies of the aligned region. The family used to be known as DUF6. Members of this family usually carry 5+5 transmembrane domains, and this domain attempts to model five of these.


Pssm-ID: 307170  Cd Length: 136  Bit Score: 36.79  E-value: 4.16e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568965788   10 LGISVAIAHGVFSGSLNILLKFLISRYQFSFLTLVQCLTSSTAALSLELLRRLGLIavppFGLSLARSFAGVAVLST-LQ 88
Cdd:pfam00892   2 KGILLALLAALIWAIYFVFSKILLRRISPLTLTFWRFLIAGILLLPFALFTGGKLV----IPLKSWLALLYLGVLGTfLG 77

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 568965788   89 SSLTLWSLRGLSLPMYVVFKRCLPLVTMLIGVLVLKNGAPSPGVLAAVLI 138
Cdd:pfam00892  78 FLLYFYGLKYVSASNASVITSLSPVFTLILSVLLLGEKLTLKQLLGIVLI 127
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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