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Conserved domains on  [gi|569003744|ref|XP_006525941|]
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major intrinsically disordered NOTCH2-binding receptor 1-like homolog isoform X2 [Mus musculus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
MINAR1_C super family cl06037
MINAR1 C-terminal domain; Major intrinsically disordered Notch2-associated receptor 1 (MINAR1) ...
 42-145 1.94e-33

MINAR1 C-terminal domain; Major intrinsically disordered Notch2-associated receptor 1 (MINAR1) is a Notch2-binding protein that has been shown to inhibit angiogenesis and breast cancer growth. This entry represents the C terminus of the MINAR1 protein.


The actual alignment was detected with superfamily member pfam06789:

Pssm-ID: 462010  Cd Length: 148  Bit Score: 114.91  E-value: 1.94e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003744   42 PASMSSVMKNNPLYGDITLEEAMEERKKSPSWTIEEYDKHSVHTNLSGHLKENPNDLRFWLGDTYTPGFDTLLKKKKKRN 121
Cdd:pfam06789  42 PVTLKSHIKRNPLYTDLRIVDTWEEKRPQPSWTIQEYDRHSLHGNLAKYLKENPNNLEYWLEDIYTPGYDSLLKRKEAEF 121

                          90       100
                  ....*....|....*....|....
gi 569003744  122 KRSKLCHMGLILLLVASILVTIVT 145
Cdd:pfam06789 122 KRSKLCKIILLIVLLICIVILVII 145
 
Name Accession Description Interval E-value
MINAR1_C pfam06789
MINAR1 C-terminal domain; Major intrinsically disordered Notch2-associated receptor 1 (MINAR1) ...
 42-145 1.94e-33

MINAR1 C-terminal domain; Major intrinsically disordered Notch2-associated receptor 1 (MINAR1) is a Notch2-binding protein that has been shown to inhibit angiogenesis and breast cancer growth. This entry represents the C terminus of the MINAR1 protein.


Pssm-ID: 462010  Cd Length: 148  Bit Score: 114.91  E-value: 1.94e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003744   42 PASMSSVMKNNPLYGDITLEEAMEERKKSPSWTIEEYDKHSVHTNLSGHLKENPNDLRFWLGDTYTPGFDTLLKKKKKRN 121
Cdd:pfam06789  42 PVTLKSHIKRNPLYTDLRIVDTWEEKRPQPSWTIQEYDRHSLHGNLAKYLKENPNNLEYWLEDIYTPGYDSLLKRKEAEF 121

                          90       100
                  ....*....|....*....|....
gi 569003744  122 KRSKLCHMGLILLLVASILVTIVT 145
Cdd:pfam06789 122 KRSKLCKIILLIVLLICIVILVII 145
 
Name Accession Description Interval E-value
MINAR1_C pfam06789
MINAR1 C-terminal domain; Major intrinsically disordered Notch2-associated receptor 1 (MINAR1) ...
 42-145 1.94e-33

MINAR1 C-terminal domain; Major intrinsically disordered Notch2-associated receptor 1 (MINAR1) is a Notch2-binding protein that has been shown to inhibit angiogenesis and breast cancer growth. This entry represents the C terminus of the MINAR1 protein.


Pssm-ID: 462010  Cd Length: 148  Bit Score: 114.91  E-value: 1.94e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569003744   42 PASMSSVMKNNPLYGDITLEEAMEERKKSPSWTIEEYDKHSVHTNLSGHLKENPNDLRFWLGDTYTPGFDTLLKKKKKRN 121
Cdd:pfam06789  42 PVTLKSHIKRNPLYTDLRIVDTWEEKRPQPSWTIQEYDRHSLHGNLAKYLKENPNNLEYWLEDIYTPGYDSLLKRKEAEF 121

                          90       100
                  ....*....|....*....|....
gi 569003744  122 KRSKLCHMGLILLLVASILVTIVT 145
Cdd:pfam06789 122 KRSKLCKIILLIVLLICIVILVII 145
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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