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Conserved domains on  [gi|569010411|ref|XP_006528231|]
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zinc finger MYM-type protein 3 isoform X10 [Mus musculus]

Protein Classification

zf-FCS and DUF3504 domain-containing protein( domain architecture ID 10654502)

protein containing domains TRASH, zf-FCS, and DUF3504

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF3504 pfam12012
Domain of unknown function (DUF3504); This presumed domain is functionally uncharacterized. ...
 1053-1220 4.47e-83

Domain of unknown function (DUF3504); This presumed domain is functionally uncharacterized. This domain is found in eukaryotes. This domain is typically between 156 to 173 amino acids in length.


:

Pssm-ID: 463430  Cd Length: 162  Bit Score: 267.98  E-value: 4.47e-83
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569010411  1053 VFSRVEEEHLWECKQLGVYSPFVLLNTLMFFNTKFFGLQTAEEHMQLSFTNVVRQSRKCttprGTTKVVSIRYYAPvrqr 1132
Cdd:pfam12012    1 VFSRVEEEHLWECKQLGAHSPIVLLNTLVYFNTKYFNLRTVEEHRRLSFSNVVRHTKPN----PREKSTYLRYYEP---- 72

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569010411  1133 kGRDTGPGKRKREDE---TILEQRENRMNPLRCPVKFYEFYLSKCPESLRTRNDVFYLQPERSCIAESPLWYSVIPMDRS 1209
Cdd:pfam12012   73 -PDQVETGGRKKRDEgvnKVVEQHENSENPLRCPVKLYEFYLSKCPESVKQRKDVFYLQPEPSCVPDSPLWYSSQPLGRN 151

                          170
                   ....*....|.
gi 569010411  1210 MLESMLNRILA 1220
Cdd:pfam12012  152 TLESMLTRILL 162
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 362-401 1.01e-06

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


:

Pssm-ID: 428958  Cd Length: 40  Bit Score: 46.21  E-value: 1.01e-06
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 569010411   362 TRVYPCVWCKTLCKNFEMLSHVDRNGKTSLFCSLCCTTSY 401
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTVIVLQNDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 217-258 8.07e-06

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


:

Pssm-ID: 428958  Cd Length: 40  Bit Score: 43.90  E-value: 8.07e-06
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 569010411   217 LGRKTCTFCKKEIWNTKDSVVVQtgPGGSFHEFCTSVCLSLY 258
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTVIVLQ--NDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 455-492 2.57e-05

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


:

Pssm-ID: 428958  Cd Length: 40  Bit Score: 42.36  E-value: 2.57e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 569010411   455 GIHLSCHYCHSLFSGKPE--VLEWQDQVFQFCCRDCCEDF 492
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTviVLQNDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 315-357 4.63e-05

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


:

Pssm-ID: 428958  Cd Length: 40  Bit Score: 41.59  E-value: 4.63e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|...
gi 569010411   315 LKTNCCDQCGAYIYARPGGlgpELLFHDGQQKRFCNTTCLGAY 357
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTV---IVLQNDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 543-579 5.81e-05

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


:

Pssm-ID: 428958  Cd Length: 40  Bit Score: 41.59  E-value: 5.81e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 569010411   543 LCCITCTYCSQTCQRG---VTEQLDGSTWDFCSEDCKTKY 579
Cdd:pfam06467    1 LVKATCWFCKKLIKNKptvIVLQNDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 584-620 4.11e-04

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


:

Pssm-ID: 428958  Cd Length: 40  Bit Score: 38.89  E-value: 4.11e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 569010411   584 CKAARCHACKRQGKLLET---IHWRGQIRHFCNQQCLLRF 620
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTvivLQNDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 410-447 1.73e-03

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


:

Pssm-ID: 428958  Cd Length: 40  Bit Score: 37.35  E-value: 1.73e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 569010411   410 GPPRPCSFCRRSLSDPCYYNKVDR--TVYQFCSPSCWTKF 447
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTVIVLQNdgSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 497-533 3.92e-03

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


:

Pssm-ID: 428958  Cd Length: 40  Bit Score: 36.19  E-value: 3.92e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 569010411   497 GVVSQCEHCRQEKLLHEK---LRFSGVEKSFCSEGCVLLY 533
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTvivLQNDGSVGQFCSQSCLDSY 40
TRASH smart00746
metallochaperone-like domain;
180-216 8.14e-03

metallochaperone-like domain;


:

Pssm-ID: 214799  Cd Length: 39  Bit Score: 35.43  E-value: 8.14e-03
                            10        20        30
                    ....*....|....*....|....*....|....*....
gi 569010411    180 CAHCRTPLQKGQTA--YQRKGLPQLFCSSSCLTTYSKKP 216
Cdd:smart00746    1 CSFCGKDIYNPGTGimVVNDGKVYYFCSSKCLSKFKKKR 39
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 273-309 9.42e-03

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


:

Pssm-ID: 428958  Cd Length: 40  Bit Score: 35.04  E-value: 9.42e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 569010411   273 ADATRCSICQKTGEVLHE---VSNGSVVHRLCSDSCFSKF 309
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTvivLQNDGSVGQFCSQSCLDSY 40
 
Name Accession Description Interval E-value
DUF3504 pfam12012
Domain of unknown function (DUF3504); This presumed domain is functionally uncharacterized. ...
 1053-1220 4.47e-83

Domain of unknown function (DUF3504); This presumed domain is functionally uncharacterized. This domain is found in eukaryotes. This domain is typically between 156 to 173 amino acids in length.


Pssm-ID: 463430  Cd Length: 162  Bit Score: 267.98  E-value: 4.47e-83
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569010411  1053 VFSRVEEEHLWECKQLGVYSPFVLLNTLMFFNTKFFGLQTAEEHMQLSFTNVVRQSRKCttprGTTKVVSIRYYAPvrqr 1132
Cdd:pfam12012    1 VFSRVEEEHLWECKQLGAHSPIVLLNTLVYFNTKYFNLRTVEEHRRLSFSNVVRHTKPN----PREKSTYLRYYEP---- 72

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569010411  1133 kGRDTGPGKRKREDE---TILEQRENRMNPLRCPVKFYEFYLSKCPESLRTRNDVFYLQPERSCIAESPLWYSVIPMDRS 1209
Cdd:pfam12012   73 -PDQVETGGRKKRDEgvnKVVEQHENSENPLRCPVKLYEFYLSKCPESVKQRKDVFYLQPEPSCVPDSPLWYSSQPLGRN 151

                          170
                   ....*....|.
gi 569010411  1210 MLESMLNRILA 1220
Cdd:pfam12012  152 TLESMLTRILL 162
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 362-401 1.01e-06

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 46.21  E-value: 1.01e-06
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 569010411   362 TRVYPCVWCKTLCKNFEMLSHVDRNGKTSLFCSLCCTTSY 401
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTVIVLQNDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 217-258 8.07e-06

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 43.90  E-value: 8.07e-06
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 569010411   217 LGRKTCTFCKKEIWNTKDSVVVQtgPGGSFHEFCTSVCLSLY 258
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTVIVLQ--NDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 455-492 2.57e-05

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 42.36  E-value: 2.57e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 569010411   455 GIHLSCHYCHSLFSGKPE--VLEWQDQVFQFCCRDCCEDF 492
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTviVLQNDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 315-357 4.63e-05

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 41.59  E-value: 4.63e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|...
gi 569010411   315 LKTNCCDQCGAYIYARPGGlgpELLFHDGQQKRFCNTTCLGAY 357
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTV---IVLQNDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 543-579 5.81e-05

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 41.59  E-value: 5.81e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 569010411   543 LCCITCTYCSQTCQRG---VTEQLDGSTWDFCSEDCKTKY 579
Cdd:pfam06467    1 LVKATCWFCKKLIKNKptvIVLQNDGSVGQFCSQSCLDSY 40
TRASH smart00746
metallochaperone-like domain;
367-405 1.15e-04

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 40.44  E-value: 1.15e-04
                            10        20        30
                    ....*....|....*....|....*....|....*....
gi 569010411    367 CVWCKTLCKNFEMLSHVDRNGKTSLFCSLCCTTSYKVKQ 405
Cdd:smart00746    1 CSFCGKDIYNPGTGIMVVNDGKVYYFCSSKCLSKFKKKR 39
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 584-620 4.11e-04

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 38.89  E-value: 4.11e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 569010411   584 CKAARCHACKRQGKLLET---IHWRGQIRHFCNQQCLLRF 620
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTvivLQNDGSVGQFCSQSCLDSY 40
TRASH smart00746
metallochaperone-like domain;
320-361 5.17e-04

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 38.90  E-value: 5.17e-04
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|..
gi 569010411    320 CDQCGAYIYaRPGGlgPELLFHDGQQKRFCNTTCLGAYKKKN 361
Cdd:smart00746    1 CSFCGKDIY-NPGT--GIMVVNDGKVYYFCSSKCLSKFKKKR 39
TRASH smart00746
metallochaperone-like domain;
460-496 5.82e-04

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 38.51  E-value: 5.82e-04
                            10        20        30
                    ....*....|....*....|....*....|....*....
gi 569010411    460 CHYCHSLFS--GKPEVLEWQDQVFQFCCRDCCEDFKRLR 496
Cdd:smart00746    1 CSFCGKDIYnpGTGIMVVNDGKVYYFCSSKCLSKFKKKR 39
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 410-447 1.73e-03

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 37.35  E-value: 1.73e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 569010411   410 GPPRPCSFCRRSLSDPCYYNKVDR--TVYQFCSPSCWTKF 447
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTVIVLQNdgSVGQFCSQSCLDSY 40
TRASH smart00746
metallochaperone-like domain;
548-580 1.84e-03

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 36.97  E-value: 1.84e-03
                            10        20        30
                    ....*....|....*....|....*....|....*.
gi 569010411    548 CTYCSQTCQRGVTE---QLDGSTWDFCSEDCKTKYL 580
Cdd:smart00746    1 CSFCGKDIYNPGTGimvVNDGKVYYFCSSKCLSKFK 36
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 497-533 3.92e-03

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 36.19  E-value: 3.92e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 569010411   497 GVVSQCEHCRQEKLLHEK---LRFSGVEKSFCSEGCVLLY 533
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTvivLQNDGSVGQFCSQSCLDSY 40
TRASH smart00746
metallochaperone-like domain;
180-216 8.14e-03

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 35.43  E-value: 8.14e-03
                            10        20        30
                    ....*....|....*....|....*....|....*....
gi 569010411    180 CAHCRTPLQKGQTA--YQRKGLPQLFCSSSCLTTYSKKP 216
Cdd:smart00746    1 CSFCGKDIYNPGTGimVVNDGKVYYFCSSKCLSKFKKKR 39
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 273-309 9.42e-03

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 35.04  E-value: 9.42e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 569010411   273 ADATRCSICQKTGEVLHE---VSNGSVVHRLCSDSCFSKF 309
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTvivLQNDGSVGQFCSQSCLDSY 40
 
Name Accession Description Interval E-value
DUF3504 pfam12012
Domain of unknown function (DUF3504); This presumed domain is functionally uncharacterized. ...
 1053-1220 4.47e-83

Domain of unknown function (DUF3504); This presumed domain is functionally uncharacterized. This domain is found in eukaryotes. This domain is typically between 156 to 173 amino acids in length.


Pssm-ID: 463430  Cd Length: 162  Bit Score: 267.98  E-value: 4.47e-83
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569010411  1053 VFSRVEEEHLWECKQLGVYSPFVLLNTLMFFNTKFFGLQTAEEHMQLSFTNVVRQSRKCttprGTTKVVSIRYYAPvrqr 1132
Cdd:pfam12012    1 VFSRVEEEHLWECKQLGAHSPIVLLNTLVYFNTKYFNLRTVEEHRRLSFSNVVRHTKPN----PREKSTYLRYYEP---- 72

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 569010411  1133 kGRDTGPGKRKREDE---TILEQRENRMNPLRCPVKFYEFYLSKCPESLRTRNDVFYLQPERSCIAESPLWYSVIPMDRS 1209
Cdd:pfam12012   73 -PDQVETGGRKKRDEgvnKVVEQHENSENPLRCPVKLYEFYLSKCPESVKQRKDVFYLQPEPSCVPDSPLWYSSQPLGRN 151

                          170
                   ....*....|.
gi 569010411  1210 MLESMLNRILA 1220
Cdd:pfam12012  152 TLESMLTRILL 162
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 362-401 1.01e-06

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 46.21  E-value: 1.01e-06
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 569010411   362 TRVYPCVWCKTLCKNFEMLSHVDRNGKTSLFCSLCCTTSY 401
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTVIVLQNDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 217-258 8.07e-06

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 43.90  E-value: 8.07e-06
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 569010411   217 LGRKTCTFCKKEIWNTKDSVVVQtgPGGSFHEFCTSVCLSLY 258
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTVIVLQ--NDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 455-492 2.57e-05

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 42.36  E-value: 2.57e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 569010411   455 GIHLSCHYCHSLFSGKPE--VLEWQDQVFQFCCRDCCEDF 492
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTviVLQNDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 315-357 4.63e-05

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 41.59  E-value: 4.63e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|...
gi 569010411   315 LKTNCCDQCGAYIYARPGGlgpELLFHDGQQKRFCNTTCLGAY 357
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTV---IVLQNDGSVGQFCSQSCLDSY 40
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 543-579 5.81e-05

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 41.59  E-value: 5.81e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 569010411   543 LCCITCTYCSQTCQRG---VTEQLDGSTWDFCSEDCKTKY 579
Cdd:pfam06467    1 LVKATCWFCKKLIKNKptvIVLQNDGSVGQFCSQSCLDSY 40
TRASH smart00746
metallochaperone-like domain;
367-405 1.15e-04

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 40.44  E-value: 1.15e-04
                            10        20        30
                    ....*....|....*....|....*....|....*....
gi 569010411    367 CVWCKTLCKNFEMLSHVDRNGKTSLFCSLCCTTSYKVKQ 405
Cdd:smart00746    1 CSFCGKDIYNPGTGIMVVNDGKVYYFCSSKCLSKFKKKR 39
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 584-620 4.11e-04

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 38.89  E-value: 4.11e-04
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 569010411   584 CKAARCHACKRQGKLLET---IHWRGQIRHFCNQQCLLRF 620
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTvivLQNDGSVGQFCSQSCLDSY 40
TRASH smart00746
metallochaperone-like domain;
320-361 5.17e-04

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 38.90  E-value: 5.17e-04
                            10        20        30        40
                    ....*....|....*....|....*....|....*....|..
gi 569010411    320 CDQCGAYIYaRPGGlgPELLFHDGQQKRFCNTTCLGAYKKKN 361
Cdd:smart00746    1 CSFCGKDIY-NPGT--GIMVVNDGKVYYFCSSKCLSKFKKKR 39
TRASH smart00746
metallochaperone-like domain;
460-496 5.82e-04

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 38.51  E-value: 5.82e-04
                            10        20        30
                    ....*....|....*....|....*....|....*....
gi 569010411    460 CHYCHSLFS--GKPEVLEWQDQVFQFCCRDCCEDFKRLR 496
Cdd:smart00746    1 CSFCGKDIYnpGTGIMVVNDGKVYYFCSSKCLSKFKKKR 39
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 410-447 1.73e-03

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 37.35  E-value: 1.73e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 569010411   410 GPPRPCSFCRRSLSDPCYYNKVDR--TVYQFCSPSCWTKF 447
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTVIVLQNdgSVGQFCSQSCLDSY 40
TRASH smart00746
metallochaperone-like domain;
548-580 1.84e-03

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 36.97  E-value: 1.84e-03
                            10        20        30
                    ....*....|....*....|....*....|....*.
gi 569010411    548 CTYCSQTCQRGVTE---QLDGSTWDFCSEDCKTKYL 580
Cdd:smart00746    1 CSFCGKDIYNPGTGimvVNDGKVYYFCSSKCLSKFK 36
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 497-533 3.92e-03

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 36.19  E-value: 3.92e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 569010411   497 GVVSQCEHCRQEKLLHEK---LRFSGVEKSFCSEGCVLLY 533
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTvivLQNDGSVGQFCSQSCLDSY 40
TRASH smart00746
metallochaperone-like domain;
180-216 8.14e-03

metallochaperone-like domain;


Pssm-ID: 214799  Cd Length: 39  Bit Score: 35.43  E-value: 8.14e-03
                            10        20        30
                    ....*....|....*....|....*....|....*....
gi 569010411    180 CAHCRTPLQKGQTA--YQRKGLPQLFCSSSCLTTYSKKP 216
Cdd:smart00746    1 CSFCGKDIYNPGTGimVVNDGKVYYFCSSKCLSKFKKKR 39
zf-FCS pfam06467
MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM ...
 273-309 9.42e-03

MYM-type Zinc finger with FCS sequence motif; MYM-type zinc fingers were identified in MYM family proteins. Human protein Swiss:Q14202 is involved in a chromosomal translocation and may be responsible for X-linked retardation in XQ13.1. Swiss:Q9UBW7 is also involved in disease. In myeloproliferative disorders it is fused to FGF receptor 1; in atypical myeloproliferative disorders it is rearranged. Members of the family generally are involved in development. This Zn-finger domain functions as a transcriptional trans-activator of late vaccinia viral genes, and orthologues are also found in all nucleocytoplasmic large DNA viruses, NCLDV. This domain is also found fused to the C termini of recombinases from certain prokaryotic transposons.


Pssm-ID: 428958  Cd Length: 40  Bit Score: 35.04  E-value: 9.42e-03
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 569010411   273 ADATRCSICQKTGEVLHE---VSNGSVVHRLCSDSCFSKF 309
Cdd:pfam06467    1 LVKATCWFCKKLIKNKPTvivLQNDGSVGQFCSQSCLDSY 40
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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