|
Name |
Accession |
Description |
Interval |
E-value |
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
131-783 |
5.47e-15 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 80.10 E-value: 5.47e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 131 RRLQATNPDLTQTVSLVVEREKQKSEAKDRkvleiLQVKDSKIQELEQTESVLKQELHDLVKLKTLVDEENAFLRKELCD 210
Cdd:TIGR02168 260 AELQELEEKLEELRLEVSELEEEIEELQKE-----LYALANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDE 334
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 211 LQKKFKDKSQEVKDAKECVQSKEEQN----------RLVIKNLEEENERLRTRCTDLLNDLEKLRNQEAHWRKEKHSVDT 280
Cdd:TIGR02168 335 LAEELAELEEKLEELKEELESLEAELeeleaeleelESRLEELEEQLETLRSKVAQLELQIASLNNEIERLEARLERLED 414
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 281 RVKVLEENLIEAKKEIESAQTKynVVSQQLNNKQAELLQKDMDITLIRKELQELQNVYKQNSAHTAQQADLIQQLQALNM 360
Cdd:TIGR02168 415 RRERLQQEIEELLKKLEEAELK--ELQAELEELEEELEELQEELERLEEALEELREELEEAEQALDAAERELAQLQARLD 492
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 361 DTQKVLRNQEDVHT--AESMSYQKLYNELHMCF--------ETTKSNEVMLRQSVVNLQGQLFQKEQENVKLKEKLEESQ 430
Cdd:TIGR02168 493 SLERLQENLEGFSEgvKALLKNQSGLSGILGVLselisvdeGYEAAIEAALGGRLQAVVVENLNAAKKAIAFLKQNELGR 572
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 431 GTAPSLSPHDSDSSHSGKAPLSTLETLMISQKSEIEYLQKKLKVANEKLMANRSCDQDFSEkGTEGKHKEPP-------- 502
Cdd:TIGR02168 573 VTFLPLDSIKGTEIQGNDREILKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVLVVDDLDN-ALELAKKLRPgyrivtld 651
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 503 ---VKRSRSLSPKSSFMGSEEL---RKLKKAERKIENLEKTLQLKSQENDELRDAHEKRKERLqmlhtnyravkEQLKQW 576
Cdd:TIGR02168 652 gdlVRPGGVITGGSAKTNSSILerrREIEELEEKIEELEEKIAELEKALAELRKELEELEEEL-----------EQLRKE 720
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 577 EEDSGMAESRQMKRAEPHQLRQEDSDAVWNELayfKRENQELMVQKMTLQDELDELKMHMSIDKTTIQELNRCMAEKREE 656
Cdd:TIGR02168 721 LEELSRQISALRKDLARLEAEVEQLEERIAQL---SKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEE 797
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 657 qlFRQHEDAEVKKSTPEKNEKAISEETLQKVIELENRLKSFEKNSRKLKEESKRLKKENDFLKSHLKHYQEDSEAREKEL 736
Cdd:TIGR02168 798 --LKALREALDELRAELTLLNEEAANLRERLESLERRIAATERRLEDLEEQIEELSEDIESLAAEIEELEELIEELESEL 875
|
650 660 670 680
....*....|....*....|....*....|....*....|....*..
gi 568926913 737 EQLLRVSKDVEHDKSELQTKITALETEVTTLRRQVTEAKALRGKDEE 783
Cdd:TIGR02168 876 EALLNERASLEEALALLRSELEELSEELRELESKRSELRRELEELRE 922
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
154-741 |
4.13e-10 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 64.19 E-value: 4.13e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 154 KSEAKDRKVLEIL---QVKDSKIQELEQTESVLKQELHDLVKLKTLVDEENAFLRKELCDLQKKFKDKSQEVKDAKECVQ 230
Cdd:COG1196 219 KEELKELEAELLLlklRELEAELEELEAELEELEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELA 298
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 231 SKEEQnrlviknLEEENERLRtrctDLLNDLEKLRNQEAHWRKEKHSVDTRVKVLEENLIEAKKEIESAQTKYNVVSQQL 310
Cdd:COG1196 299 RLEQD-------IARLEERRR----ELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEAL 367
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 311 NNKQAELLQKDMDITLIRKELQELQN---VYKQNSAHTAQQADLIQQLQALNMDTQKVLRNQEDVHTAESMSYQKLYNEL 387
Cdd:COG1196 368 LEAEAELAEAEEELEELAEELLEALRaaaELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEA 447
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 388 HMCFETTKSNEVMLRQSVVNLQGQLFQKEQENVKLKEKLEESqgtAPSLSPHDSDSSHSGKAPLSTLETLMISQKSEI-- 465
Cdd:COG1196 448 AEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEA---AARLLLLLEAEADYEGFLEGVKAALLLAGLRGLag 524
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 466 ---------EYLQKKLKVANEKLMANRSCDQDFSEKGTEGKHKE-----------PPVKRSRSLSPKSSFMGSEELRKLK 525
Cdd:COG1196 525 avavligveAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAakagratflplDKIRARAALAAALARGAIGAAVDLV 604
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 526 KAERKIENLEKTLQLKS-QENDELRDAHEKRKERLQMLHTNYRAVKEQLKQWEEDSGMAESRQMKRAEPHQLRQEDSDAV 604
Cdd:COG1196 605 ASDLREADARYYVLGDTlLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEEL 684
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 605 WNELAYFKRENQELMVQKMTLQDELDELKMHMSIDKTTIQELNRCMAEKREEQLFRQHEDAEVKKSTPEKNEKAI-SEET 683
Cdd:COG1196 685 AERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPpDLEE 764
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 684 LQKVIE-LENRLKSFEK-NSRKLkEESKRLKKENDFLKSHLkhyqEDSEAREKELEQLLR 741
Cdd:COG1196 765 LERELErLEREIEALGPvNLLAI-EEYEELEERYDFLSEQR----EDLEEARETLEEAIE 819
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
149-773 |
1.53e-09 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 62.39 E-value: 1.53e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 149 EREKQKSEAKDRKVLEILQVKDSKIQELEQTESVLKQELHDL-VKLKTLVDEENAFLRKELCDL-------QKKFKDKSQ 220
Cdd:TIGR02169 236 ERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELnKKIKDLGEEEQLRVKEKIGELeaeiaslERSIAEKER 315
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 221 EVKDA-KECVQSKEEQNRLV--IKNLEEENERLRTRCTDLLNDLEKLRNQEAHWRKEKHSVDTRVKVLEENLIEAKKEIE 297
Cdd:TIGR02169 316 ELEDAeERLAKLEAEIDKLLaeIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEEVDKEFAETRDELKDYREKLE 395
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 298 SAQTKYNVVSQQLNNKQAELLQKDMDITLIRKELQELQNVYKQNSAHTAQQADLIQQLQALNMDTQKVLRNQEDVHTAES 377
Cdd:TIGR02169 396 KLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQELYDLK 475
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 378 MSYQKLYNELHMC------FETT-----------KSNEVMLR---QSVVNLQGQLFQKEQENVK---------LKEKLEE 428
Cdd:TIGR02169 476 EEYDRVEKELSKLqrelaeAEAQaraseervrggRAVEEVLKasiQGVHGTVAQLGSVGERYATaievaagnrLNNVVVE 555
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 429 SQGTAPSlSPHDSDSSHSGKA---PLSTL--ETLMISQKSE----------IEYLQKKLKV---------------ANEK 478
Cdd:TIGR02169 556 DDAVAKE-AIELLKRRKAGRAtflPLNKMrdERRDLSILSEdgvigfavdlVEFDPKYEPAfkyvfgdtlvvedieAARR 634
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 479 LMANR---SCDQDFSEKG---TEGKHKEP-PVKRSRSLSPKSSFMgSEELRKLKKA-ERKIENLEKTLQLKSQENDELRD 550
Cdd:TIGR02169 635 LMGKYrmvTLEGELFEKSgamTGGSRAPRgGILFSRSEPAELQRL-RERLEGLKRElSSLQSELRRIENRLDELSQELSD 713
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 551 AHEKRKE---RLQMLHTNYRAVKEQLKQWEED-----SGMAESRQMKRAEPHQLRQEDSDAVWNELAYFKRENQELMVQK 622
Cdd:TIGR02169 714 ASRKIGEiekEIEQLEQEEEKLKERLEELEEDlssleQEIENVKSELKELEARIEELEEDLHKLEEALNDLEARLSHSRI 793
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 623 MTLQDELDELK-MHMSIDKTTI---QELNRCMAEKREEQLFRQHEDAEVKKSTPEKNEKAISEETLQKVI-ELENRLKSF 697
Cdd:TIGR02169 794 PEIQAELSKLEeEVSRIEARLReieQKLNRLTLEKEYLEKEIQELQEQRIDLKEQIKSIEKEIENLNGKKeELEEELEEL 873
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568926913 698 EKNSRKLKEESKRLKKENDFLKSHLKHYQEDSEAREKELEQLlrvskdvEHDKSELQTKITALETEVTTLRRQVTE 773
Cdd:TIGR02169 874 EAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKK-------RKRLSELKAKLEALEEELSEIEDPKGE 942
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
150-776 |
7.15e-07 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 53.53 E-value: 7.15e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 150 REKQKSEAKDRKVLEILQVKDSKIQELEQTESVLKQELHDLVKLktlVDEENAFLRKELCDLQKKFKDKSQEVKDAKECV 229
Cdd:TIGR02169 230 KEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQL---LEELNKKIKDLGEEEQLRVKEKIGELEAEIASL 306
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 230 QSKEEQNRLVIKNLEEENERLRTRCTDLLNDLEKLRNQEAHWRKEKHSVDTRVKVLEE---------------------N 288
Cdd:TIGR02169 307 ERSIAEKERELEDAEERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEeledlraeleevdkefaetrdE 386
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 289 LIEAKKEIESAQTKYNVVSQQLNNKQAELLQKDMDITLIRKELQELQNVYKQNSAHTAQQADLIQQLQALNMDTQKVLRN 368
Cdd:TIGR02169 387 LKDYREKLEKLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEAKINELEEEKEDKALEIKKQEWKLEQLAADLSK 466
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 369 QEDVHTAESMSYQKLYNELHMC------FETT-----------KSNEVMLR---QSVVNLQGQLFQKEQENVK------- 421
Cdd:TIGR02169 467 YEQELYDLKEEYDRVEKELSKLqrelaeAEAQaraseervrggRAVEEVLKasiQGVHGTVAQLGSVGERYATaievaag 546
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 422 --LKEKLEESQGTAPSlSPHDSDSSHSGKA---PLSTL--ETLMISQKSE----------IEYLQKKLKV---------- 474
Cdd:TIGR02169 547 nrLNNVVVEDDAVAKE-AIELLKRRKAGRAtflPLNKMrdERRDLSILSEdgvigfavdlVEFDPKYEPAfkyvfgdtlv 625
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 475 -----ANEKLMANR---SCDQDFSEKG---TEGKHKEP-PVKRSRSLSPKSSFMgSEELRKLKKA-ERKIENLEKTLQLK 541
Cdd:TIGR02169 626 vedieAARRLMGKYrmvTLEGELFEKSgamTGGSRAPRgGILFSRSEPAELQRL-RERLEGLKRElSSLQSELRRIENRL 704
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 542 SQENDELRDAHEKRKE---RLQMLHTNYRAVKEQLKQWEEDSgmaesrqmkraephQLRQEDSDAVWNELAYFKRENQEL 618
Cdd:TIGR02169 705 DELSQELSDASRKIGEiekEIEQLEQEEEKLKERLEELEEDL--------------SSLEQEIENVKSELKELEARIEEL 770
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 619 MVQKMTLQDELDELKMH--MSIDKTTIQELNRCMAEKREEQLFRQHEDAEVKKSTPEKN--EKAIsEETLQKVIELENRL 694
Cdd:TIGR02169 771 EEDLHKLEEALNDLEARlsHSRIPEIQAELSKLEEEVSRIEARLREIEQKLNRLTLEKEylEKEI-QELQEQRIDLKEQI 849
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 695 KSFEKnsrklKEESKRLKKENdfLKSHLKHYQEDSEAREKELEQLLRVSKDVEHDKSELQTKITALETEVTTLRRQVTEA 774
Cdd:TIGR02169 850 KSIEK-----EIENLNGKKEE--LEEELEELEAALRDLESRLGDLKKERDELEAQLRELERKIEELEAQIEKKRKRLSEL 922
|
..
gi 568926913 775 KA 776
Cdd:TIGR02169 923 KA 924
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
148-775 |
8.49e-07 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 53.19 E-value: 8.49e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 148 VEREKQKSEAKDRKVLEILQVKDSKIQELE-QTESVLKQELHDLVKLKTLVDEENAflRKELCDLQKKFKDKSQEVKDAK 226
Cdd:pfam05483 97 IEAELKQKENKLQENRKIIEAQRKAIQELQfENEKVSLKLEEEIQENKDLIKENNA--TRHLCNLLKETCARSAEKTKKY 174
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 227 EcvqSKEEQNRLVIKNLEEENERLRTRCTDLLNDLEKLRNQEAHWRKEKHSvdtRVKVLEEnliEAKKEIESAQTKYNVV 306
Cdd:pfam05483 175 E---YEREETRQVYMDLNNNIEKMILAFEELRVQAENARLEMHFKLKEDHE---KIQHLEE---EYKKEINDKEKQVSLL 245
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 307 SQQLNNKQaellQKDMDITLIRKElqelqnvykqnSAHTAQQADLIQQLQALNMdtqKVLRNQEDVHTAEsmsyqklYNE 386
Cdd:pfam05483 246 LIQITEKE----NKMKDLTFLLEE-----------SRDKANQLEEKTKLQDENL---KELIEKKDHLTKE-------LED 300
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 387 LHMCFETTKSNEVMLRQSVVNLQGQLFQKEQENVKLKEKLEESQGTAPSLSPHDsdsshsgKAPLSTLETLMISQKSEIE 466
Cdd:pfam05483 301 IKMSLQRSMSTQKALEEDLQIATKTICQLTEEKEAQMEELNKAKAAHSFVVTEF-------EATTCSLEELLRTEQQRLE 373
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 467 YLQKKLKVANEKLMaNRSCDQDFSEKGTEGKHKEppvkrsrsLSPKSSFMGSEElrKLKKAERKIENLEKTLQLKSQEND 546
Cdd:pfam05483 374 KNEDQLKIITMELQ-KKSSELEEMTKFKNNKEVE--------LEELKKILAEDE--KLLDEKKQFEKIAEELKGKEQELI 442
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 547 ELRDAHEKRKERLQMLHTNYRAVKEQ-LKQWEEDSGMAESRQMKRAEphqlrqedsdaVWNELAYFKRENQELMVQKmtl 625
Cdd:pfam05483 443 FLLQAREKEIHDLEIQLTAIKTSEEHyLKEVEDLKTELEKEKLKNIE-----------LTAHCDKLLLENKELTQEA--- 508
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 626 QDELDELKMHMsidkttiQELNRCmaEKREEQLFRQHEDAEVKKSTPEKNEKAISEETLQKVIELENRLKSFEKNSRKLK 705
Cdd:pfam05483 509 SDMTLELKKHQ-------EDIINC--KKQEERMLKQIENLEEKEMNLRDELESVREEFIQKGDEVKCKLDKSEENARSIE 579
|
570 580 590 600 610 620 630
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 706 EESKRLKKENDFLKSHLKHYQEDSEAREKELEQLLRVSKDVEHDKSELQTKITALETEVTTLRRQVTEAK 775
Cdd:pfam05483 580 YEVLKKEKQMKILENKCNNLKKQIENKNKNIEELHQENKALKKKGSAENKQLNAYEIKVNKLELELASAK 649
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
148-801 |
1.55e-06 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 52.84 E-value: 1.55e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 148 VEREKQKSEAKDRKVleilqvKDSKIQELEQTESVLKQElhdlvKLKTLVDEENAFLRKELCDLQK-KFKDKSQEVKDAK 226
Cdd:PTZ00121 1111 AEEARKAEEAKKKAE------DARKAEEARKAEDARKAE-----EARKAEDAKRVEIARKAEDARKaEEARKAEDAKKAE 1179
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 227 ECVQSKEEQNRLVIKNLEEENERLRTRCTDLLNDLEKLRNQEAHWRKEKHSVDTRVKVLEENLIEAKKEIESAQTKYNVV 306
Cdd:PTZ00121 1180 AARKAEEVRKAEELRKAEDARKAEAARKAEEERKAEEARKAEDAKKAEAVKKAEEAKKDAEEAKKAEEERNNEEIRKFEE 1259
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 307 SQQLNNKQAELLQKDMDitliRKELQELQNVYKQNSAHTAQQADLIQQLQALNMDTQKVLRNQEDVHTAESMsyQKLYNE 386
Cdd:PTZ00121 1260 ARMAHFARRQAAIKAEE----ARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAKKADEAKKKAEEA--KKKADA 1333
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 387 LHMCFETTKSNEVMLRQSVVNLQGQLFQKEQENVKLKEKLEESQGTAPSLSPHDSDSSHSGKAPLSTLETLMISQK-SEI 465
Cdd:PTZ00121 1334 AKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKKKADElKKA 1413
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 466 EYLQKKLKVANEKLMANRSCDQ-----DFSEKGTEGKHKEPPVKRSRSLSPKSS-FMGSEELRKLKKAERKIENLEKTLQ 539
Cdd:PTZ00121 1414 AAAKKKADEAKKKAEEKKKADEakkkaEEAKKADEAKKKAEEAKKAEEAKKKAEeAKKADEAKKKAEEAKKADEAKKKAE 1493
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 540 LKSQENDELRDAHEKRKERLQMLHTNYRAVKEQLKQWEEDSGMAESR---------------------QMKRAEPHQLRQ 598
Cdd:PTZ00121 1494 EAKKKADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAKKADEAKkaeekkkadelkkaeelkkaeEKKKAEEAKKAE 1573
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 599 EDSDAVWNELAYFKRENQELMVQKMTLQDELDELKMHMSI----DKTTIQELNRCMAEKREEQLFRQHEDAEVKKSTPEK 674
Cdd:PTZ00121 1574 EDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKkaeeAKIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELK 1653
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 675 NEKaisEETLQKVIELENRLKSFEKNSRKLKEESKRLKKENDFLKSHLKHYQEDSEAREKELEQlLRVSKDVEHDKSELQ 754
Cdd:PTZ00121 1654 KAE---EENKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEE-KKKAEELKKAEEENK 1729
|
650 660 670 680
....*....|....*....|....*....|....*....|....*..
gi 568926913 755 TKITALETEVTTLRRQVTEAKALRGKDEEVVCPEERAHRPTDKAKSE 801
Cdd:PTZ00121 1730 IKAEEAKKEAEEDKKKAEEAKKDEEEKKKIAHLKKEEEKKAEEIRKE 1776
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
151-689 |
1.58e-06 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 52.63 E-value: 1.58e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 151 EKQKSEAKDRKVLEILQVKDSKIQELEQTESVLKQELHDLVKLKTLVDEENAFLRKELCDLQKKFKDKSQEVKDAKE--- 227
Cdd:COG1196 289 EEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEall 368
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 228 CVQSKEEQNRLVIKNLEEENERLRTRCTDLLNDLEKLRNQEAHWRKEKHSVDTRVKVLEENLIEAKKEIESAQTKYNVVS 307
Cdd:COG1196 369 EAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAA 448
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 308 QQLNNKQAELLQKDMDITLIRKELQELQNVYKQNSAHTAQQADLIQQLQALNMDTQKVLRNQEDVHTAESMS--YQKLYN 385
Cdd:COG1196 449 EEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLLAGLRglAGAVAV 528
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 386 ELHMCFETTKSNEVMLRQSVVNLQGQLFQKEQENVKLKEKLEESQGTAPSLSPHDSDSSHSGKAPLSTLETLMISQKSEI 465
Cdd:COG1196 529 LIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDL 608
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 466 EYLQKKLKVANEKLMANRSCDQDFSEKGTEGKHKEPPVKRSRSLSPKSSFMGSEELRKLKKAERKIENLEKTLQLKSQEN 545
Cdd:COG1196 609 READARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERL 688
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 546 DELRDAHEKRKERLQMLHTNYRAVKEQLKQWEEDSGMAESRQMKRAEPHQLRQEDSDAVWNELAYfkrENQELMVQKMTL 625
Cdd:COG1196 689 AEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEAL---EELPEPPDLEEL 765
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568926913 626 QDELDELKMHM----SIDKTTIQELNRcmAEKREEQLFRQHEDAevkkstpeknEKAIseETLQKVIE 689
Cdd:COG1196 766 ERELERLEREIealgPVNLLAIEEYEE--LEERYDFLSEQREDL----------EEAR--ETLEEAIE 819
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
519-780 |
8.37e-06 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 50.06 E-value: 8.37e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 519 EELRKLKKAERKIENL----EKTLQLKSQENDELRDAHEKRKERLQMLHTNYRAVKEQLKQWEEDSGMAESR-QMKRAEP 593
Cdd:PRK03918 179 ERLEKFIKRTENIEELikekEKELEEVLREINEISSELPELREELEKLEKEVKELEELKEEIEELEKELESLeGSKRKLE 258
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 594 HQLRQEDSDAvwNELAYFKRENQELMVQKMTLQDELDELKMHMSIDKTTIQELNRcmAEKREEQLFRQHEDAEVKKSTPE 673
Cdd:PRK03918 259 EKIRELEERI--EELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDELRE--IEKRLSRLEEEINGIEERIKELE 334
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 674 KNEKAIsEETLQKVIELENRLKSFEKNSRKLkEESKRLKKENDFLKSHLKHYQedSEAREKELEQLLRVSKDVEHDKSEL 753
Cdd:PRK03918 335 EKEERL-EELKKKLKELEKRLEELEERHELY-EEAKAKKEELERLKKRLTGLT--PEKLEKELEELEKAKEEIEEEISKI 410
|
250 260
....*....|....*....|....*..
gi 568926913 754 QTKITALETEVTTLRRQVTEAKALRGK 780
Cdd:PRK03918 411 TARIGELKKEIKELKKAIEELKKAKGK 437
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
385-805 |
1.29e-05 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 49.35 E-value: 1.29e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 385 NELHmcfettKSNEVMLRQSVVNLQGQLFQKEQENVKLKEKLEESQGTAPSLSPHDSDSSHSGKAPLSTLETLMISQKSE 464
Cdd:pfam15921 98 NELH------EKQKFYLRQSVIDLQTKLQEMQMERDAMADIRRRESQSQEDLRNQLQNTVHELEAAKCLKEDMLEDSNTQ 171
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 465 IEYLQKKLKVANEKLMANRSCDQDFSEKGTEGKHKEPPVK--RSRSLSPKSSFMGSE---ELRKLKKAERKIENLEKTLQ 539
Cdd:pfam15921 172 IEQLRKMMLSHEGVLQEIRSILVDFEEASGKKIYEHDSMStmHFRSLGSAISKILREldtEISYLKGRIFPVEDQLEALK 251
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 540 LKSQENDE-LRDAHEKRKERLQMLHTnyravkeqlkqwEEDSGMAESRQMKRAEPHQLRQEdsdavwNELAYFKRENQEL 618
Cdd:pfam15921 252 SESQNKIElLLQQHQDRIEQLISEHE------------VEITGLTEKASSARSQANSIQSQ------LEIIQEQARNQNS 313
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 619 MVQKmtlqdELDELKMHMSIDKTTIQELNRcMAEKREEQLFRQHEDAEVKKSTPEKNEKAISEETLQKVIELENRLKSFE 698
Cdd:pfam15921 314 MYMR-----QLSDLESTVSQLRSELREAKR-MYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLH 387
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 699 KNSRKL---KEESKRL---KKENDFLKSHLKHYQEDSEAREKELEQLLRVSKD-----VEHDKSELQTKITALEtEVTTL 767
Cdd:pfam15921 388 KREKELsleKEQNKRLwdrDTGNSITIDHLRRELDDRNMEVQRLEALLKAMKSecqgqMERQMAAIQGKNESLE-KVSSL 466
|
410 420 430
....*....|....*....|....*....|....*...
gi 568926913 768 RRQVTEAKALRGKDEEVVCPEERAHRPTDKAKSEMATT 805
Cdd:pfam15921 467 TAQLESTKEMLRKVVEELTAKKMTLESSERTVSDLTAS 504
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
153-358 |
1.78e-05 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 49.14 E-value: 1.78e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 153 QKSEAKDRKVLEilQVKDSKIQELEQTESVLKQelhdlvklKTLVDEENAFLRKELCDLQKKFKdksqevkdakecvQSK 232
Cdd:PRK11281 44 QLDALNKQKLLE--AEDKLVQQDLEQTLALLDK--------IDRQKEETEQLKQQLAQAPAKLR-------------QAQ 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 233 EEQNRLVIKNLEEENERLRTRC-TDLLNDLEKLRNQEAHWRKEKHSVDTRVKVLEENLIEAKKEIESAQTKYNVVSQQLN 311
Cdd:PRK11281 101 AELEALKDDNDEETRETLSTLSlRQLESRLAQTLDQLQNAQNDLAEYNSQLVSLQTQPERAQAALYANSQRLQQIRNLLK 180
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568926913 312 NK---------------QAELLQKDMDITLIRKELQ---ELQNVY-KQNSAHTAQQADLIQQLQAL 358
Cdd:PRK11281 181 GGkvggkalrpsqrvllQAEQALLNAQNDLQRKSLEgntQLQDLLqKQRDYLTARIQRLEHQLQLL 246
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
525-776 |
2.12e-05 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 48.90 E-value: 2.12e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 525 KKAERKIEnlektlqlKSQEN-DELRDAHEKRKERLQMLH------TNYRAVKEQLKQWEEDSGMAESRQmKRAEPHQLR 597
Cdd:TIGR02168 175 KETERKLE--------RTRENlDRLEDILNELERQLKSLErqaekaERYKELKAELRELELALLVLRLEE-LREELEELQ 245
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 598 QEDSDAVwNELAYFKRENQELMVQKMTLQDELDELKMHMSIDKTTIQELNRCMAEKREEQLFRQHEDAEVKKSTPEKNEk 677
Cdd:TIGR02168 246 EELKEAE-EELEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQILRERLANLERQLEELEA- 323
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 678 aISEETLQKVIELENRLKSFEKNSRKLKEESKRLKKENDFLKSHLKHYQEDSEAREKELEQLLRVSKDVEHDKSELQTKI 757
Cdd:TIGR02168 324 -QLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRLEELEEQLETLRSKVAQLELQIASLNNEI 402
|
250
....*....|....*....
gi 568926913 758 TALETEVTTLRRQVTEAKA 776
Cdd:TIGR02168 403 ERLEARLERLEDRRERLQQ 421
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
154-734 |
2.22e-05 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 48.52 E-value: 2.22e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 154 KSEAKDRKVLEILQVKDSKIQELE---QTESVLKQELHDLVKLKTLVDEENAFLRKELCDLQKKFKDKSQEVKD---AKE 227
Cdd:PRK03918 159 DYENAYKNLGEVIKEIKRRIERLEkfiKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKEleeLKE 238
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 228 CVQSKEEQNRLVIKNLEEENERLR---TRCTDLLNDLEKLRNQEAHWRKEKHSVDTRVKVLE--ENLIEAKKEIESAQTK 302
Cdd:PRK03918 239 EIEELEKELESLEGSKRKLEEKIReleERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEfyEEYLDELREIEKRLSR 318
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 303 YNVVSQQLNNKQAELLQKDMDITLIRKELQELQNVYkqnsahtaqqADLIQQLQALNMDTQKVLRNQEDVHTAESMSYQK 382
Cdd:PRK03918 319 LEEEINGIEERIKELEEKEERLEELKKKLKELEKRL----------EELEERHELYEEAKAKKEELERLKKRLTGLTPEK 388
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 383 LYNELHMcFETTKSNEVMLRQSVVNLQGQLFQKEQENVKLKEKLEESQGTAPSLSPHDSDSSHSGKAPLSTLETLMIS-Q 461
Cdd:PRK03918 389 LEKELEE-LEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELTEEHRKELLEEYTAELKRIEkE 467
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 462 KSEIEYLQKKLKVANEKLMANRSCDQDFSEKGTEGKHKEPPVKRSRSLSPKSSFMGSEELRKLKKAERKIENLEKTLQLK 541
Cdd:PRK03918 468 LKEIEEKERKLRKELRELEKVLKKESELIKLKELAEQLKELEEKLKKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKE 547
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 542 SQENDELRDAHEKRKERLQMLHTNYRAVKEQLKQWEEDSGMAESRQMKRAEPHQLRqedsdavWNELAYFKRENQELMVQ 621
Cdd:PRK03918 548 LEKLEELKKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKELEPFYNE-------YLELKDAEKELEREEKE 620
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 622 KMTLQDELDELKMHMSIDKTTIQELnrcmaEKREEQLFRQHEDAEVKKSTPEKNEKAISEETLQKVIE-LENRLKSFEKN 700
Cdd:PRK03918 621 LKKLEEELDKAFEELAETEKRLEEL-----RKELEELEKKYSEEEYEELREEYLELSRELAGLRAELEeLEKRREEIKKT 695
|
570 580 590
....*....|....*....|....*....|....
gi 568926913 701 SRKLKEESKRLKKENDFLKSHLKHYQEDSEAREK 734
Cdd:PRK03918 696 LEKLKEELEEREKAKKELEKLEKALERVEELREK 729
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
241-785 |
3.32e-05 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 48.13 E-value: 3.32e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 241 KNLEEENERLrTRCTDLLNDLEK-----------------LRNQEAHWrkEKHSVDTRVKVLEENLIEAKKEIESAQTKY 303
Cdd:TIGR02168 179 RKLERTRENL-DRLEDILNELERqlkslerqaekaerykeLKAELREL--ELALLVLRLEELREELEELQEELKEAEEEL 255
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 304 NVVSQQLNNKQAELLQKDMDITLIRKELQELQNVYKqnsAHTAQQADLIQQLQALNMDTQKVLRNQEdvhtaesmsyqkl 383
Cdd:TIGR02168 256 EELTAELQELEEKLEELRLEVSELEEEIEELQKELY---ALANEISRLEQQKQILRERLANLERQLE------------- 319
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 384 ynELHMCFETTKSNEVMLRQSVVNLQGQLFQKEQENVKLKEKLEESQGTAPSLsphdsdsshsgKAPLSTLETLMISQKS 463
Cdd:TIGR02168 320 --ELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEEL-----------ESRLEELEEQLETLRS 386
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 464 EIEYLQKKLKVANEKL--------MANRSCDQDFSEKGTEGKHKEPPVKRSRSLSPKSSFMGSEELRK-LKKAERKIENL 534
Cdd:TIGR02168 387 KVAQLELQIASLNNEIerlearleRLEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELEELQEeLERLEEALEEL 466
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 535 EKTLQLKSQENDELRDAHEKRKERLQMLHT-------NYRAVKEQLKQWEEDSGMAE--SRQMKRAEPHQLRQE------ 599
Cdd:TIGR02168 467 REELEEAEQALDAAERELAQLQARLDSLERlqenlegFSEGVKALLKNQSGLSGILGvlSELISVDEGYEAAIEaalggr 546
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 600 -------DSDAVWNELAYFKRENQ------------------ELMVQKMTLQDELDELKMHMSIDK-------------- 640
Cdd:TIGR02168 547 lqavvveNLNAAKKAIAFLKQNELgrvtflpldsikgteiqgNDREILKNIEGFLGVAKDLVKFDPklrkalsyllggvl 626
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 641 --TTIQELNRCMAEKREEQLF---------------RQHEDAEV----KKSTPEKNEKAIsEETLQKVIELENRLKSFEK 699
Cdd:TIGR02168 627 vvDDLDNALELAKKLRPGYRIvtldgdlvrpggvitGGSAKTNSsileRRREIEELEEKI-EELEEKIAELEKALAELRK 705
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 700 NSRKLKEESKRLKKENDFLKSHLKHYQEDSEAREKELEQLLRVSKDVEHDKSELQTKITALETEVTTLRRQVTEAKALRG 779
Cdd:TIGR02168 706 ELEELEEELEQLRKELEELSRQISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIE 785
|
....*.
gi 568926913 780 KDEEVV 785
Cdd:TIGR02168 786 ELEAQI 791
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
512-783 |
3.64e-05 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 48.14 E-value: 3.64e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 512 KSSFMGSEELRKLKKAERKIENLEKTLQLKSQENDELRDAHEKRKERLQMLHTNYRAVKEQLKQWEEDSGMAESRQMKRA 591
Cdd:TIGR02169 220 KREYEGYELLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQLRVKEKIGEL 299
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 592 EPHQLRQEDSdavwneLAYFKRENQELMVQKMTLQDELDELKmhmsidkTTIQELNRcmaEKREEQLFRQHEDAEVKKST 671
Cdd:TIGR02169 300 EAEIASLERS------IAEKERELEDAEERLAKLEAEIDKLL-------AEIEELER---EIEEERKRRDKLTEEYAELK 363
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 672 PEKNEKaiseetlqkVIELENRLKSFEKNSRKLKEESKR---LKKENDFLKSHLKHYQEDSEAREKELEQLLRVSKDVEH 748
Cdd:TIGR02169 364 EELEDL---------RAELEEVDKEFAETRDELKDYREKlekLKREINELKRELDRLQEELQRLSEELADLNAAIAGIEA 434
|
250 260 270
....*....|....*....|....*....|....*
gi 568926913 749 DKSELQTKITALETEVTTLRRQVTEAKALRGKDEE 783
Cdd:TIGR02169 435 KINELEEEKEDKALEIKKQEWKLEQLAADLSKYEQ 469
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
166-776 |
8.28e-05 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 46.55 E-value: 8.28e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 166 LQVKDSKIQEL--------------EQTESVLKQELHDLVKLKTLVDEENAFLRKELCDLQKKFKDKSQEVKDAKECVQS 231
Cdd:TIGR04523 91 LKKNKDKINKLnsdlskinseikndKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIKKKEKELEKLNNKYNDLKKQKEE 170
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 232 KEEQNRLVIKNLEEENERLRTRCTDLLNDLEKLRNQEAHWRKEKhSVDTRVKVLEENLIEAKKEIESAQTKYNVVSQQLN 311
Cdd:TIGR04523 171 LENELNLLEKEKLNIQKNIDKIKNKLLKLELLLSNLKKKIQKNK-SLESQISELKKQNNQLKDNIEKKQQEINEKTTEIS 249
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 312 NKQAELLQKDMDITLIRKELQELQNVYKQNSAHTAQQADLIQQLQA--LNMDTQKVLRNQEDVHTaESMSYQKLYNELHM 389
Cdd:TIGR04523 250 NTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQLNQLKSeiSDLNNQKEQDWNKELKS-ELKNQEKKLEEIQN 328
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 390 CFETTKSNEVMLRQSVVNLQGQLFQKEQENVKLKEKLEESQGTAPSLSPHDSDSshsgkapLSTLETLmISQKSEIEYLQ 469
Cdd:TIGR04523 329 QISQNNKIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSY-------KQEIKNL-ESQINDLESKI 400
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 470 KKLKVANEKLmanrscDQDFSEKGTEGKHKEPPVKRSRSlspkssfmgseelrKLKKAERKIENLEKTLQLKSQENDELR 549
Cdd:TIGR04523 401 QNQEKLNQQK------DEQIKKLQQEKELLEKEIERLKE--------------TIIKNNSEIKDLTNQDSVKELIIKNLD 460
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 550 DAHEKRKERLQMLHTNYRAVKEQLKQweedsgmaESRQMKRAEphqlrqedsdavwNELAYFKRENQELMVQKMTLQDEL 629
Cdd:TIGR04523 461 NTRESLETQLKVLSRSINKIKQNLEQ--------KQKELKSKE-------------KELKKLNEEKKELEEKVKDLTKKI 519
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 630 DELKMHMSIDKTTIQELNRCMAEKREEQLfrqhEDAEVKKSTPEKNEKaisEETLQKVIELENRLKSFEKNSRKLKEESK 709
Cdd:TIGR04523 520 SSLKEKIEKLESEKKEKESKISDLEDELN----KDDFELKKENLEKEI---DEKNKEIEELKQTQKSLKKKQEEKQELID 592
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568926913 710 RLKKENDFLKSHLKHYQEDSEAREKELEQLLRVSKDVEHDKSELQTKITALETEVTTLRRQVTEAKA 776
Cdd:TIGR04523 593 QKEKEKKDLIKEIEEKEKKISSLEKELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKETIKEIRN 659
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
463-776 |
1.19e-04 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 46.27 E-value: 1.19e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 463 SEIEYLQKKLKVANEKLMANRSCDQDFSEKGTEGKHKEPPVKRSRSLspkssfmgsEELRKLKKAER-KIENLEKTLQLK 541
Cdd:pfam17380 266 TENEFLNQLLHIVQHQKAVSERQQQEKFEKMEQERLRQEKEEKAREV---------ERRRKLEEAEKaRQAEMDRQAAIY 336
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 542 SQENdelRDAHEKRKERLQMLHTNYRAVKEQLKQWEEDSGMAESRQMKRAEPHqlRQEDSDAVWNEL-AYFKRENQELMV 620
Cdd:pfam17380 337 AEQE---RMAMERERELERIRQEERKRELERIRQEEIAMEISRMRELERLQME--RQQKNERVRQELeAARKVKILEEER 411
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 621 QKMTLQDELDELKMHMSIDKTTIQELNRCMAEK-------REEQLFRQHEDAEVKKSTPEKNEKAIS---EETLQKVIEL 690
Cdd:pfam17380 412 QRKIQQQKVEMEQIRAEQEEARQREVRRLEEERaremervRLEEQERQQQVERLRQQEEERKRKKLElekEKRDRKRAEE 491
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 691 ENRL---KSFEKNSRKLKEESKRLKKENDFLKSHLKHYQEDSEAREKELEQllRVSKDVEHDK---------SELQTKIT 758
Cdd:pfam17380 492 QRRKileKELEERKQAMIEEERKRKLLEKEMEERQKAIYEEERRREAEEER--RKQQEMEERRriqeqmrkaTEERSRLE 569
|
330
....*....|....*...
gi 568926913 759 ALETEVTTLRRQVTEAKA 776
Cdd:pfam17380 570 AMEREREMMRQIVESEKA 587
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
157-335 |
1.39e-04 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 44.53 E-value: 1.39e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 157 AKDRKVLEILQVKDSKIQELEQTESVLKQELHDLvklktlvdeenaflRKELCDLQKKFKDKSQEVKDAKECVQSKEEQn 236
Cdd:COG1579 3 PEDLRALLDLQELDSELDRLEHRLKELPAELAEL--------------EDELAALEARLEAAKTELEDLEKEIKRLELE- 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 237 rlvIKNLEEENERLRTRctdlLNDLEKLRNQEAHwRKEKHSVDTRVKVLEENLIEAKKEIESAQTKYNVVSQQLNNKQAE 316
Cdd:COG1579 68 ---IEEVEARIKKYEEQ----LGNVRNNKEYEAL-QKEIESLKRRISDLEDEILELMERIEELEEELAELEAELAELEAE 139
|
170 180
....*....|....*....|...
gi 568926913 317 LLQK----DMDITLIRKELQELQ 335
Cdd:COG1579 140 LEEKkaelDEELAELEAELEELE 162
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
285-795 |
1.46e-04 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 46.12 E-value: 1.46e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 285 LEENLIEAKKEIESAQTKYnvvsQQLNNKQAELLQKDMDITLIRKELQELQNvykQNSAHTAQQADLIQQLQALnmdtqK 364
Cdd:TIGR00618 227 ELKHLREALQQTQQSHAYL----TQKREAQEEQLKKQQLLKQLRARIEELRA---QEAVLEETQERINRARKAA-----P 294
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 365 VLRNQEDVHTAEsMSYQKLYNELhmcfettksnevmlrQSVVNLQGQLFQKEQENVKLKEKLEESQGTAPSLSPHDSDSS 444
Cdd:TIGR00618 295 LAAHIKAVTQIE-QQAQRIHTEL---------------QSKMRSRAKLLMKRAAHVKQQSSIEEQRRLLQTLHSQEIHIR 358
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 445 HSGKAPLSTLETLMiSQKSEIEYLQKKLKVANEKLMANRSCDQDFSEKGTEGKHKEPPVKRSRSLSPKSSFMGSEELRKL 524
Cdd:TIGR00618 359 DAHEVATSIREISC-QQHTLTQHIHTLQQQKTTLTQKLQSLCKELDILQREQATIDTRTSAFRDLQGQLAHAKKQQELQQ 437
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 525 KKAERKIENLEKTLQLKSQENDELRDAHEKRKERLQMLHTnyravKEQLKQWEEDSGMAESrqmKRAEPHQLRQEDSDAV 604
Cdd:TIGR00618 438 RYAELCAAAITCTAQCEKLEKIHLQESAQSLKEREQQLQT-----KEQIHLQETRKKAVVL---ARLLELQEEPCPLCGS 509
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 605 WNELAYFKRENQELMVQKMTLQDELDELKMHMSIDKTTIQELnrcmaekreeqlfrqheDAEVKKSTPEKNEKAISEETL 684
Cdd:TIGR00618 510 CIHPNPARQDIDNPGPLTRRMQRGEQTYAQLETSEEDVYHQL-----------------TSERKQRASLKEQMQEIQQSF 572
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 685 QKVIELENRLKSFEKNSRKLKEESKRLKKENDFLKSHLKHYQEDSEAREKELEQLLRVSKDVEHDKSELQTKITALETEV 764
Cdd:TIGR00618 573 SILTQCDNRSKEDIPNLQNITVRLQDLTEKLSEAEDMLACEQHALLRKLQPEQDLQDVRLHLQQCSQELALKLTALHALQ 652
|
490 500 510
....*....|....*....|....*....|.
gi 568926913 765 TTLRRQVTEAKALRGKDEEVVCPEERAHRPT 795
Cdd:TIGR00618 653 LTLTQERVREHALSIRVLPKELLASRQLALQ 683
|
|
| PRK11281 |
PRK11281 |
mechanosensitive channel MscK; |
139-361 |
1.80e-04 |
|
mechanosensitive channel MscK;
Pssm-ID: 236892 [Multi-domain] Cd Length: 1113 Bit Score: 45.67 E-value: 1.80e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 139 DLTQTVSLVVEREKQKSEAKDRKvleilqvkdskiQELEQTESVLKQELHDLVKLKTLVDEENA--FLRKELCDLQKKFK 216
Cdd:PRK11281 64 DLEQTLALLDKIDRQKEETEQLK------------QQLAQAPAKLRQAQAELEALKDDNDEETRetLSTLSLRQLESRLA 131
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 217 DKSQEVKDAKECVQskeEQNRLVIkNLEEENERLRTRCTDLLNDLEKLRNQeahwrkeKHSVDTRVKVL---EENLIEAK 293
Cdd:PRK11281 132 QTLDQLQNAQNDLA---EYNSQLV-SLQTQPERAQAALYANSQRLQQIRNL-------LKGGKVGGKALrpsQRVLLQAE 200
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568926913 294 KEIESAQTKYNVVSQQLNNKQAELLQKDMD-----ITLIRKELQELQNV----YKQNSAHTAQQADLIQQLQALNMD 361
Cdd:PRK11281 201 QALLNAQNDLQRKSLEGNTQLQDLLQKQRDyltarIQRLEHQLQLLQEAinskRLTLSEKTVQEAQSQDEAARIQAN 277
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
204-767 |
2.55e-04 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 45.01 E-value: 2.55e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 204 LRKELCDLQKKFKDKSQEVKDAKECVQSKEEQnrlvIKNLEEENERLRTRCTDLLNDLEKLRNQeahwrkekhsvdtrVK 283
Cdd:TIGR04523 38 LEKKLKTIKNELKNKEKELKNLDKNLNKDEEK----INNSNNKIKILEQQIKDLNDKLKKNKDK--------------IN 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 284 VLEENLIEAKKEIESAQTKYNVVSQQLNNKQAELLQKDMDITLIRKEL----QELQNVYKQNSAHTAQQADLIQQLQALN 359
Cdd:TIGR04523 100 KLNSDLSKINSEIKNDKEQKNKLEVELNKLEKQKKENKKNIDKFLTEIkkkeKELEKLNNKYNDLKKQKEELENELNLLE 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 360 MDTQKVLRNQEDVHTAESMSYQKL-----YNELHMCFETTKSNevmLRQSVVNLQGQLFQKEQENVKLKEKLEESQGTAP 434
Cdd:TIGR04523 180 KEKLNIQKNIDKIKNKLLKLELLLsnlkkKIQKNKSLESQISE---LKKQNNQLKDNIEKKQQEINEKTTEISNTQTQLN 256
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 435 SLSPHDSDSSHSGKAPLSTLETlmisQKSEIEYLQKKLKVANEKLMA-NRSCDQDFSEK-GTEGKHKEPPVKRSRSLSPK 512
Cdd:TIGR04523 257 QLKDEQNKIKKQLSEKQKELEQ----NNKKIKELEKQLNQLKSEISDlNNQKEQDWNKElKSELKNQEKKLEEIQNQISQ 332
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 513 SSfmgseelRKLKKAERKIENLEKTLQLKSQENDELRDAHEKRKERLQMLHTNYRAVKEQLKQWEEDSGMAESRQMKRAE 592
Cdd:TIGR04523 333 NN-------KIISQLNEQISQLKKELTNSESENSEKQRELEEKQNEIEKLKKENQSYKQEIKNLESQINDLESKIQNQEK 405
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 593 PHQLRQEDSDAVWNELAYFKRENQELMVQKMTLQDELDELKMHMSIDKTTIQELNRcmaekreeqlFRQHEDAEVKKSTP 672
Cdd:TIGR04523 406 LNQQKDEQIKKLQQEKELLEKEIERLKETIIKNNSEIKDLTNQDSVKELIIKNLDN----------TRESLETQLKVLSR 475
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 673 E-KNEKAISEETLQKVIELENRLKSFEKNSRKLKEESKRLKKENDFLKShlkhyqedseaREKELEQllrvskdvehDKS 751
Cdd:TIGR04523 476 SiNKIKQNLEQKQKELKSKEKELKKLNEEKKELEEKVKDLTKKISSLKE-----------KIEKLES----------EKK 534
|
570
....*....|....*.
gi 568926913 752 ELQTKITALETEVTTL 767
Cdd:TIGR04523 535 EKESKISDLEDELNKD 550
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
213-783 |
2.63e-04 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 45.05 E-value: 2.63e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 213 KKFKDKSQEVKDAKECVQSKEEQNRLVIKNLEEENERLRTRCTDL---LNDLEKLRNQEAHWRKEKHSVDTRVKVLEENL 289
Cdd:PRK03918 182 EKFIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLekeVKELEELKEEIEELEKELESLEGSKRKLEEKI 261
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 290 IEAKKEIESAQTKYNVVSQQLnnKQAELLQKDMD-----ITLIRKELQELQNVYKQNSAHTAQQADLIQQLQALNMDTQK 364
Cdd:PRK03918 262 RELEERIEELKKEIEELEEKV--KELKELKEKAEeyiklSEFYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEER 339
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 365 VLRNQEdvhtaESMSYQKLYNEL---HMCFETTKSNEVMLRQsvvnLQGQLFQKEQEnvKLKEKLEESQgtapslsphds 441
Cdd:PRK03918 340 LEELKK-----KLKELEKRLEELeerHELYEEAKAKKEELER----LKKRLTGLTPE--KLEKELEELE----------- 397
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 442 dsshSGKAPLSTLETLMISQKSEIEYLQKKLKVANEKLmanrscdqdfsekgTEGKHKEPPVKRSRSLSPKSSFMgSEEL 521
Cdd:PRK03918 398 ----KAKEEIEEEISKITARIGELKKEIKELKKAIEEL--------------KKAKGKCPVCGRELTEEHRKELL-EEYT 458
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 522 RKLKKAERKIENLEKTLQLKSQENDELRDAHEKRKERLQMlhtnyRAVKEQLKQWEEdsgmaesrqmkraEPHQLRQEDS 601
Cdd:PRK03918 459 AELKRIEKELKEIEEKERKLRKELRELEKVLKKESELIKL-----KELAEQLKELEE-------------KLKKYNLEEL 520
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 602 DAVWNELAYFKRENQELMVQKMTLQDELDELKMHmsidKTTIQELNRCMAEKREEQLFRQHEDAEVKKSTPEKNEKAISE 681
Cdd:PRK03918 521 EKKAEEYEKLKEKLIKLKGEIKSLKKELEKLEEL----KKKLAELEKKLDELEEELAELLKELEELGFESVEELEERLKE 596
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 682 etLQKVIELENRLKSFEKNSRKLKEESKRLKKENDFLKSHLKHYQEDSEAREKELEQLLRVSKDVEHDK-----SELQTK 756
Cdd:PRK03918 597 --LEPFYNEYLELKDAEKELEREEKELKKLEEELDKAFEELAETEKRLEELRKELEELEKKYSEEEYEElreeyLELSRE 674
|
570 580
....*....|....*....|....*..
gi 568926913 757 ITALETEVTTLRRQVTEAKALRGKDEE 783
Cdd:PRK03918 675 LAGLRAELEELEKRREEIKKTLEKLKE 701
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
259-478 |
2.72e-04 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 44.75 E-value: 2.72e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 259 NDLEKLRNQEAHWRKEKHSVDTRVKVLEENLIEAKKEIESAQTKYNVVSQQLNNKQAELLQKDMDITLIRKELQELQNVY 338
Cdd:COG4942 27 AELEQLQQEIAELEKELAALKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAELEAQKEEL 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 339 kqnsahtaqqADLIQQLQAL-NMDTQKVLRNQEDVHTAE-SMSYQKLYN----ELHMCFETTKSNEVMLRQSVVNLQGQL 412
Cdd:COG4942 107 ----------AELLRALYRLgRQPPLALLLSPEDFLDAVrRLQYLKYLAparrEQAEELRADLAELAALRAELEAERAEL 176
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568926913 413 FQKEQENVKLKEKLEESQGTAPSLSPHDSDSSHSGKAPLSTLETLMISQKSEIEYLQKKLKVANEK 478
Cdd:COG4942 177 EALLAELEEERAALEALKAERQKLLARLEKELAELAAELAELQQEAEELEALIARLEAEAAAAAER 242
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
519-829 |
2.78e-04 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 45.13 E-value: 2.78e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 519 EELRKLKKAeRKIENLEKTLQLKSQEndELRDAHEKRKERLQMLHTNYRAVkEQLKQWEEDSGMAESRQMKRAEPHQLRQ 598
Cdd:PTZ00121 1167 EEARKAEDA-KKAEAARKAEEVRKAE--ELRKAEDARKAEAARKAEEERKA-EEARKAEDAKKAEAVKKAEEAKKDAEEA 1242
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 599 EDSDAVWNELAYFKRENQELMVQKMTLQDELDElkmhmsiDKTTIQELNRCMAEKREEQLFRQHEDAEVKKSTPEKNEKA 678
Cdd:PTZ00121 1243 KKAEEERNNEEIRKFEEARMAHFARRQAAIKAE-------EARKADELKKAEEKKKADEAKKAEEKKKADEAKKKAEEAK 1315
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 679 ISEETLQKVIELENRLKSFEKNSRKLKEESKRLKKENDFLKSHLKHYQEDSEAREKELEQLLR----VSKDVEHDKSELQ 754
Cdd:PTZ00121 1316 KADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKkadaAKKKAEEKKKADE 1395
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 755 TKITALET-----EVTTLRRQVTEAKALRGKDEEVVCPEERAHRPTDKAKSEMATTDVRARRCD---CKTATTKVKFKAA 826
Cdd:PTZ00121 1396 AKKKAEEDkkkadELKKAAAAKKKADEAKKKAEEKKKADEAKKKAEEAKKADEAKKKAEEAKKAeeaKKKAEEAKKADEA 1475
|
...
gi 568926913 827 KRK 829
Cdd:PTZ00121 1476 KKK 1478
|
|
| Golgin_A5 |
pfam09787 |
Golgin subfamily A member 5; Members of this family of proteins are involved in maintaining ... |
164-310 |
3.11e-04 |
|
Golgin subfamily A member 5; Members of this family of proteins are involved in maintaining Golgi structure. They stimulate the formation of Golgi stacks and ribbons, and are involved in intra-Golgi retrograde transport. Two main interactions have been characterized: one with RAB1A that has been activated by GTP-binding and another with isoform CASP of CUTL1.
Pssm-ID: 462900 [Multi-domain] Cd Length: 305 Bit Score: 43.98 E-value: 3.11e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 164 EILQVKDSKIQELEQTESVLKQELHDLVKLKTLVDEENAFLRKELCDLQKKFKDKSQEVKDAKECVQSKEEQNRLVIKNL 243
Cdd:pfam09787 51 ELRQERDLLREEIQKLRGQIQQLRTELQELEAQQQEEAESSREQLQELEEQLATERSARREAEAELERLQEELRYLEEEL 130
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 244 EEENERLRTRCTDLLNDLEKLRNQ---EAHWRKEKHSVDTRVKVLEENLIEAKKEIESAQTKYNVVSQQL 310
Cdd:pfam09787 131 RRSKATLQSRIKDREAEIEKLRNQltsKSQSSSSQSELENRLHQLTETLIQKQTMLEALSTEKNSLVLQL 200
|
|
| Cast |
pfam10174 |
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part ... |
522-761 |
3.42e-04 |
|
RIM-binding protein of the cytomatrix active zone; This is a family of proteins that form part of the CAZ (cytomatrix at the active zone) complex which is involved in determining the site of synaptic vesicle fusion. The C-terminus is a PDZ-binding motif that binds directly to RIM (a small G protein Rab-3A effector). The family also contains four coiled-coil domains.
Pssm-ID: 431111 [Multi-domain] Cd Length: 766 Bit Score: 44.81 E-value: 3.42e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 522 RKLKKAERKIENLEKTLQLKSQENDELrdahekrKERLQMLHTNYRAVKEQLKQWEEdsGMAESRQMKRAEPHQLRQEDS 601
Cdd:pfam10174 394 RKINVLQKKIENLQEQLRDKDKQLAGL-------KERVKSLQTDSSNTDTALTTLEE--ALSEKERIIERLKEQREREDR 464
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 602 DAVwNELAYFKRENQELMVQKMTLQDELDELKMHMSIDKTTIQELNRCMaekreeqlfrqhedaeVKKSTPEKNEKAISE 681
Cdd:pfam10174 465 ERL-EELESLKKENKDLKEKVSALQPELTEKESSLIDLKEHASSLASSG----------------LKKDSKLKSLEIAVE 527
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 682 ETLQKVIELENRLK---SFEKNSRKLKEESKRLKKendfLKSHLKHYQEDSEAREKELEQLLRVSKDVEHDKSELQTKIT 758
Cdd:pfam10174 528 QKKEECSKLENQLKkahNAEEAVRTNPEINDRIRL----LEQEVARYKEESGKAQAEVERLLGILREVENEKNDKDKKIA 603
|
...
gi 568926913 759 ALE 761
Cdd:pfam10174 604 ELE 606
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
519-784 |
6.21e-04 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 44.16 E-value: 6.21e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 519 EELR-KLKKAERKIENLEKTLQLKSQENDELRDAHEKRKERLQMLHTNYRAVKEQLKQWEEdsgmaesrqmkraephqlr 597
Cdd:COG1196 270 EELRlELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEE------------------- 330
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 598 qedsdavwnELAYFKRENQELMVQKMTLQDELDELKMHMSIDKTTIQELNRCMAEKREEQLFRQHEDAEVKKSTpeknek 677
Cdd:COG1196 331 ---------ELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAA------ 395
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 678 aisEETLQKVIELENRLKSFEKNSRKLKEESKRLKKENDFLKSHLKHYQEDSEAREKELEQLLRVSKDVEHDKSELQTKI 757
Cdd:COG1196 396 ---AELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEA 472
|
250 260
....*....|....*....|....*..
gi 568926913 758 TALETEVTTLRRQVTEAKALRGKDEEV 784
Cdd:COG1196 473 ALLEAALAELLEELAEAAARLLLLLEA 499
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
150-322 |
6.31e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 43.99 E-value: 6.31e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 150 REKQKSEAKDRKVLEILQVKDSKIQELEQTESVLKQELHDLVKLKTLVDeenafLRKELCDLQKKFKDKSQEVKDAkecv 229
Cdd:COG4717 81 KEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLLQLLP-----LYQELEALEAELAELPERLEEL---- 151
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 230 qskeEQNRLVIKNLEEENERLRTRCTDLLNDLEKLRNQ-EAHWRKEKHSVDTRVKVLEENLIEAKKEIESAQTKYNVVSQ 308
Cdd:COG4717 152 ----EERLEELRELEEELEELEAELAELQEELEELLEQlSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEE 227
|
170
....*....|....
gi 568926913 309 QLNNKQAELLQKDM 322
Cdd:COG4717 228 ELEQLENELEAAAL 241
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
90-801 |
7.31e-04 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 43.89 E-value: 7.31e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 90 EGLSSEEAKATRSQLLEEELSSLKEELALCQADKEfvwslwrrlqatnpdltqtvslVVEREKQKSEAKDRKVLEILQVK 169
Cdd:TIGR02168 327 ELESKLDELAEELAELEEKLEELKEELESLEAELE----------------------ELEAELEELESRLEELEEQLETL 384
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 170 DSKIQELEQTESVLKQELHDLVKLKTLVDEENAFLRKELCDLQKKFKDKsqevkdAKECVQSKEEQNRLVIKNLEEENER 249
Cdd:TIGR02168 385 RSKVAQLELQIASLNNEIERLEARLERLEDRRERLQQEIEELLKKLEEA------ELKELQAELEELEEELEELQEELER 458
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 250 LRTRCTDLLNDLEKLRNQEAHWRKEKHSVDTRVKVLEENLieakkeiESAQTKYNVVSQQLNNKQaellqkdmDITLIRK 329
Cdd:TIGR02168 459 LEEALEELREELEEAEQALDAAERELAQLQARLDSLERLQ-------ENLEGFSEGVKALLKNQS--------GLSGILG 523
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 330 ELQELQNVykQNSAHTAQQADLIQQLQALnmdtqkVLRNQEDVHTAESMSYQKLYNELHMCFETTksnevmlrqsvvnLQ 409
Cdd:TIGR02168 524 VLSELISV--DEGYEAAIEAALGGRLQAV------VVENLNAAKKAIAFLKQNELGRVTFLPLDS-------------IK 582
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 410 GQLFQKEQENVklKEKLEESQGTAPSLSPHDSDSSHSGKAPLSTL---ETLMISQKSEIEYLQKKLKVANEKLMANRSCD 486
Cdd:TIGR02168 583 GTEIQGNDREI--LKNIEGFLGVAKDLVKFDPKLRKALSYLLGGVlvvDDLDNALELAKKLRPGYRIVTLDGDLVRPGGV 660
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 487 QDFSEKGTEGKhkepPVKRSRSLspkssfmgsEELR-KLKKAERKIENLEKTLQLKSQENDELRDAHEKRKERLQMLHTN 565
Cdd:TIGR02168 661 ITGGSAKTNSS----ILERRREI---------EELEeKIEELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQ 727
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 566 YRAVKEQLKQWEEDSGMAESRQMKRAEPHQLRQEDSDAVWNELAYFKRENQELMVQKMTLQDELDELKMHMSIDKTTIQE 645
Cdd:TIGR02168 728 ISALRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELEERLEEAEEELAEAEAEIEELEAQIEQLKEELKALREALDE 807
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 646 LNrcmaekreEQLFRQHEDAEVKKSTPEKNEKAIS-------------EETLQKVIELENRLKSFEKNSRKLKEESKRLK 712
Cdd:TIGR02168 808 LR--------AELTLLNEEAANLRERLESLERRIAaterrledleeqiEELSEDIESLAAEIEELEELIEELESELEALL 879
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 713 KENDFLKSHLKHYQEDSEAREKELEQLLRVSKDVEHDKSELQTKITALETEVTTLR---RQVTEAKALRGKDEEVVCPEE 789
Cdd:TIGR02168 880 NERASLEEALALLRSELEELSEELRELESKRSELRRELEELREKLAQLELRLEGLEvriDNLQERLSEEYSLTLEEAEAL 959
|
730
....*....|..
gi 568926913 790 RAHRPTDKAKSE 801
Cdd:TIGR02168 960 ENKIEDDEEEAR 971
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
510-742 |
7.87e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 43.60 E-value: 7.87e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 510 SPKSSFMGSEELRKLKKAERKIENLEKTLQLKSQENDELRDAHEKRKERLQMLHTNYRAVKEQLKQWEEDSGMAESRQmK 589
Cdd:COG4717 34 AGKSTLLAFIRAMLLERLEKEADELFKPQGRKPELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAEL-E 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 590 RAEPHQLRQEDSDAVWNELAYFKRENQELMvqkmTLQDELDELKMHMsidkTTIQELNRCMAEKREEQLFRQHEDAEVKK 669
Cdd:COG4717 113 ELREELEKLEKLLQLLPLYQELEALEAELA----ELPERLEELEERL----EELRELEEELEELEAELAELQEELEELLE 184
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 568926913 670 STPEKNEKAIsEETLQKVIELENRLKSFEKNSRKLKEESKRLKKENDFLKSHLKHYQEdsEAREKELEQLLRV 742
Cdd:COG4717 185 QLSLATEEEL-QDLAEELEELQQRLAELEEELEEAQEELEELEEELEQLENELEAAAL--EERLKEARLLLLI 254
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
151-765 |
9.24e-04 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 43.51 E-value: 9.24e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 151 EKQKSEAKDR--KVLEILQVKDSKIQELEQTESVLKQELHDLVKLKTLVDEenafLRKELCDLQKKFKDKSQEVKDAKEC 228
Cdd:PRK03918 192 EELIKEKEKEleEVLREINEISSELPELREELEKLEKEVKELEELKEEIEE----LEKELESLEGSKRKLEEKIRELEER 267
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 229 VQSKEEQnrlvIKNLEEENERLrtrctdllndleklrnQEAHWRKEKHSvdtRVKVLEENLIEAKKEIESAQTKYNVVSQ 308
Cdd:PRK03918 268 IEELKKE----IEELEEKVKEL----------------KELKEKAEEYI---KLSEFYEEYLDELREIEKRLSRLEEEIN 324
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 309 QLNNKQAELLQKDMDITLIRKELQELQNVYkqnsahtaqqADLIQQLQALNMDTQKVLRNQEDVHTAESMSYQKLYNELH 388
Cdd:PRK03918 325 GIEERIKELEEKEERLEELKKKLKELEKRL----------EELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEKELE 394
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 389 McFETTKSNEVMLRQSVVNLQGQLFQKEQENVKLKEKLEESQGTAPSLSPHDSDSSHsgkaplstlETLMISQKSEIEYL 468
Cdd:PRK03918 395 E-LEKAKEEIEEEISKITARIGELKKEIKELKKAIEELKKAKGKCPVCGRELTEEHR---------KELLEEYTAELKRI 464
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 469 QKKLKVANEKLmanrscdqdfSEKGTEGKHKEPPVKRSRSLSPKSSFMG-----SEELRK--LKKAERKIENLEKTLQLK 541
Cdd:PRK03918 465 EKELKEIEEKE----------RKLRKELRELEKVLKKESELIKLKELAEqlkelEEKLKKynLEELEKKAEEYEKLKEKL 534
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 542 SQENDELRDAhEKRKERLQMLHTNYRAVKEQLKQWEEDSGMAESRQMKRAEPhqlRQEDSDAVWNELAYFKRENQELMVQ 621
Cdd:PRK03918 535 IKLKGEIKSL-KKELEKLEELKKKLAELEKKLDELEEELAELLKELEELGFE---SVEELEERLKELEPFYNEYLELKDA 610
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 622 KMTLQDELDELKMHMSIDKTTIQELNRcmAEKREEQLFRQHEDAEVKKStpEKNEKAISEETLQKVIELENRLKSFEKNS 701
Cdd:PRK03918 611 EKELEREEKELKKLEEELDKAFEELAE--TEKRLEELRKELEELEKKYS--EEEYEELREEYLELSRELAGLRAELEELE 686
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 568926913 702 RKLKEESKRLKKendflkshLKHYQEDSEAREKELEQLLRVSKDVEhdksELQTKITALETEVT 765
Cdd:PRK03918 687 KRREEIKKTLEK--------LKEELEEREKAKKELEKLEKALERVE----ELREKVKKYKALLK 738
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
149-389 |
9.53e-04 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 43.19 E-value: 9.53e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 149 EREKQKSEAKDRKVLEILQ----VKDSKIQELE-------QTESVLKQELHDLVKLKTLVDEEnaflrkelcdlQKKFKD 217
Cdd:pfam17380 349 ELERIRQEERKRELERIRQeeiaMEISRMRELErlqmerqQKNERVRQELEAARKVKILEEER-----------QRKIQQ 417
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 218 KSQEVKDA-KECVQSKEEQNRLVIKNLEEENERLRTRCTDLLNDLEKLRNQEAHWRKEKHSVDTrvkvleenliEAKKEI 296
Cdd:pfam17380 418 QKVEMEQIrAEQEEARQREVRRLEEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLELEK----------EKRDRK 487
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 297 ESAQTKYNVVSQQLNNKQAELLQKDMDITLIRKELQELQN-VYKQNSAHTAQQADLIQQlqalNMDTQKVLRNQEDVHTA 375
Cdd:pfam17380 488 RAEEQRRKILEKELEERKQAMIEEERKRKLLEKEMEERQKaIYEEERRREAEEERRKQQ----EMEERRRIQEQMRKATE 563
|
250
....*....|....
gi 568926913 376 ESMSYQKLYNELHM 389
Cdd:pfam17380 564 ERSRLEAMEREREM 577
|
|
| PRK05771 |
PRK05771 |
V-type ATP synthase subunit I; Validated |
618-767 |
1.07e-03 |
|
V-type ATP synthase subunit I; Validated
Pssm-ID: 235600 [Multi-domain] Cd Length: 646 Bit Score: 42.99 E-value: 1.07e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 618 LMVQKM------TLQDELDElkmhmsidktTIQELnrcmaekREEQLFrQHEDAEVKKSTpEKNEKAISEetLQKVIELE 691
Cdd:PRK05771 1 LAPVRMkkvlivTLKSYKDE----------VLEAL-------HELGVV-HIEDLKEELSN-ERLRKLRSL--LTKLSEAL 59
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 568926913 692 NRLKSFEKNSRKLKEESKRLKKENdflkshlkhYQEDSEAREKELEQLLRVSKDVEHDKSELQTKITALETEVTTL 767
Cdd:PRK05771 60 DKLRSYLPKLNPLREEKKKVSVKS---------LEELIKDVEEELEKIEKEIKELEEEISELENEIKELEQEIERL 126
|
|
| COG5022 |
COG5022 |
Myosin heavy chain [General function prediction only]; |
128-740 |
1.11e-03 |
|
Myosin heavy chain [General function prediction only];
Pssm-ID: 227355 [Multi-domain] Cd Length: 1463 Bit Score: 43.14 E-value: 1.11e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 128 SLWRRLQATNPDLTQTVSLVVEREKQKSEAKDRKVLEiLQVKDSKIQELEQTESVLKQELHDLVK-LKTLVDEENAFLRK 206
Cdd:COG5022 850 KFGRSLKAKKRFSLLKKETIYLQSAQRVELAERQLQE-LKIDVKSISSLKLVNLELESEIIELKKsLSSDLIENLEFKTE 928
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 207 ELCDLqKKFKDKSQeVKDAKEC-VQSKEEQNRLViknleEENERLRTRCTDLLNDLEKLRNQEAHWRKEKHSVDTRVKVL 285
Cdd:COG5022 929 LIARL-KKLLNNID-LEEGPSIeYVKLPELNKLH-----EVESKLKETSEEYEDLLKKSTILVREGNKANSELKNFKKEL 1001
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 286 EENLIEakKEIESAQTKynvvsqQLNNKQAEL--LQKDMDITL-IRKELQELQNVYKQNSAHTAQQADLIQQLQALNMDT 362
Cdd:COG5022 1002 AELSKQ--YGALQESTK------QLKELPVEVaeLQSASKIISsESTELSILKPLQKLKGLLLLENNQLQARYKALKLRR 1073
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 363 QKVLRNQEDVHTAESMSYQKLynelhmcfETTKSNEVMLRQSVVNLQGQLFQKEQENVKLKEKLEESqGTAPSLSPHDSD 442
Cdd:COG5022 1074 ENSLLDDKQLYQLESTENLLK--------TINVKDLEVTNRNLVKPANVLQFIVAQMIKLNLLQEIS-KFLSQLVNTLEP 1144
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 443 SSHSGKAPLSTLETlMISQKSEIEYLQKKLKVAN--EKLMANRSCDQDFSEKGTEGKHKEPPV----KRSRSLSPKSSfm 516
Cdd:COG5022 1145 VFQKLSVLQLELDG-LFWEANLEALPSPPPFAALseKRLYQSALYDEKSKLSSSEVNDLKNELialfSKIFSGWPRGD-- 1221
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 517 gseelrKLKKAERKIENLEKTLQ-LKSQENDELRDAHEKRKERLQMLHTNYRAVKEQLKQWEEDSgmaesrqMKRAEPHQ 595
Cdd:COG5022 1222 ------KLKKLISEGWVPTEYSTsLKGFNNLNKKFDTPASMSNEKLLSLLNSIDNLLSSYKLEEE-------VLPATINS 1288
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 596 LRQEDSDAVWNELayFKRENqelmvqKMTLQdELDELKMHMSIDKTTIQELNRCMAEKREEQLFRQHEDAEVKKSTPEKn 675
Cdd:COG5022 1289 LLQYINVGLFNAL--RTKAS------SLRWK-SATEVNYNSEELDDWCREFEISDVDEELEELIQAVKVLQLLKDDLNK- 1358
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 568926913 676 ekaiseetLQKVIELENRLKSFEKNsrKLKEESKRLKKENDFLKSHLKHYQEDSEAREKELEQLL 740
Cdd:COG5022 1359 --------LDELLDACYSLNPAEIQ--NLKSRYDPADKENNLPKEILKKIEALLIKQELQLSLEG 1413
|
|
| CALCOCO1 |
pfam07888 |
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ... |
584-792 |
1.32e-03 |
|
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.
Pssm-ID: 462303 [Multi-domain] Cd Length: 488 Bit Score: 42.57 E-value: 1.32e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 584 ESRQMKRAEPHQLRQEDSDAVWNELAYFKRENQELMVQKMTLQDELDELKMHMSIDKTTIQELNR----------CMAEK 653
Cdd:pfam07888 37 EECLQERAELLQAQEAANRQREKEKERYKRDREQWERQRRELESRVAELKEELRQSREKHEELEEkykelsasseELSEE 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 654 ReEQLFRQHEDAEVKKSTPEKNEKAISEETLQKVIELENRLKSFEKNSRKLKEEskrlKKENDFLKSHLKHYQEDSEARE 733
Cdd:pfam07888 117 K-DALLAQRAAHEARIRELEEDIKTLTQRVLERETELERMKERAKKAGAQRKEE----EAERKQLQAKLQQTEEELRSLS 191
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 568926913 734 KELEQLLRVSKDVEHDKSELQTKITALETEVTTLRRQVTEAKALRgkdEEVVCPEERAH 792
Cdd:pfam07888 192 KEFQELRNSLAQRDTQVLQLQDTITTLTQKLTTAHRKEAENEALL---EELRSLQERLN 247
|
|
| COG4026 |
COG4026 |
Uncharacterized conserved protein, contains TOPRIM domain, potential nuclease [General ... |
684-763 |
1.61e-03 |
|
Uncharacterized conserved protein, contains TOPRIM domain, potential nuclease [General function prediction only];
Pssm-ID: 443204 [Multi-domain] Cd Length: 287 Bit Score: 41.64 E-value: 1.61e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 684 LQKVIELENRLKSFEKNSRKLKEESKRLKKENDFLKSHLKHYQEDSEAREKELEQLLRVSKDVEHDKSELQTKITALETE 763
Cdd:COG4026 127 IPEYNELREELLELKEKIDEIAKEKEKLTKENEELESELEELREEYKKLREENSILEEEFDNIKSEYSDLKSRFEELLKK 206
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
522-714 |
2.30e-03 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 41.67 E-value: 2.30e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 522 RKLKKAERKIENLEKTLQLKSQENDELRDAHEKRKERL-QMLHTNYRavkeqlkqweedsgmaesrqMKRAEPHQ--LRQ 598
Cdd:COG4942 69 RRIRALEQELAALEAELAELEKEIAELRAELEAQKEELaELLRALYR--------------------LGRQPPLAllLSP 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 599 EDSDAVWNELAYFKRENQELMVQKMTLQDELDELkmhmsidKTTIQELNRCMAEKREEQLFRQHEDAEVKKstpEKNEKA 678
Cdd:COG4942 129 EDFLDAVRRLQYLKYLAPARREQAEELRADLAEL-------AALRAELEAERAELEALLAELEEERAALEA---LKAERQ 198
|
170 180 190
....*....|....*....|....*....|....*..
gi 568926913 679 ISEETLQKVI-ELENRLKSFEKNSRKLKEESKRLKKE 714
Cdd:COG4942 199 KLLARLEKELaELAAELAELQQEAEELEALIARLEAE 235
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
539-788 |
2.51e-03 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 41.95 E-value: 2.51e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 539 QLKSQ-ENDELRDAHEkrkeRLQMLHTNYRAVKEQLKQWEEDSGMAESRQMK---RAEPHQLRQEDSDAVWNELA----- 609
Cdd:PRK02224 191 QLKAQiEEKEEKDLHE----RLNGLESELAELDEEIERYEEQREQARETRDEadeVLEEHEERREELETLEAEIEdlret 266
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 610 ---------YFKRENQELMVQKMTLQDELDELKMHMSIDKTTIQ--ELNRCMAEKREEQLFRQHEDAEVKKSTPEKNEKA 678
Cdd:PRK02224 267 iaeterereELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEavEARREELEDRDEELRDRLEECRVAAQAHNEEAES 346
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 679 ISEEtlqkVIELENRlksfeknSRKLKEESKRLKKENDFLKSHLKHYQEDSEAREKELEQLLR--------------VSK 744
Cdd:PRK02224 347 LRED----ADDLEER-------AEELREEAAELESELEEAREAVEDRREEIEELEEEIEELRErfgdapvdlgnaedFLE 415
|
250 260 270 280
....*....|....*....|....*....|....*....|....
gi 568926913 745 DVEHDKSELQTKITALETEVTTLRRQVTEAKALRgkdEEVVCPE 788
Cdd:PRK02224 416 ELREERDELREREAELEATLRTARERVEEAEALL---EAGKCPE 456
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
256-694 |
3.11e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 41.68 E-value: 3.11e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 256 DLLNDLEKLRNQEAHWRKEKHSVDTrvkvLEENLIEAKKEIESAQTKYNVVSQQLNNKQAELLQKDmditlIRKELQELQ 335
Cdd:COG4717 75 ELEEELKEAEEKEEEYAELQEELEE----LEEELEELEAELEELREELEKLEKLLQLLPLYQELEA-----LEAELAELP 145
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 336 NVYKQNSAHTAQQADLIQQLQALNmdtQKVLRNQEDVHTAESMSYQKLYNELhmcfETTKSNEVMLRQSVVNLQGQLFQK 415
Cdd:COG4717 146 ERLEELEERLEELRELEEELEELE---AELAELQEELEELLEQLSLATEEEL----QDLAEELEELQQRLAELEEELEEA 218
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 416 EQENVKLKEKLEESQGTAPSLSPHDSDSSHSGK----APLSTLETLMISQKSEIE------------------YLQKKLK 473
Cdd:COG4717 219 QEELEELEEELEQLENELEAAALEERLKEARLLlliaAALLALLGLGGSLLSLILtiagvlflvlgllallflLLAREKA 298
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 474 VANEKLMANRSCDQDFSEKGTEGKHKEPPVKRSRSLSPKSSFMGSEELRKLKKAERKIENLEKTLQLKSQENDE---LRD 550
Cdd:COG4717 299 SLGKEAEELQALPALEELEEEELEELLAALGLPPDLSPEELLELLDRIEELQELLREAEELEEELQLEELEQEIaalLAE 378
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 551 AHEKRKERLQMLHTNYRAVKEQLKQWEEDSgmAESRQMKRAEPHQLRQEDSDAVWNELAYFKRENQELMVQKMTLQDELD 630
Cdd:COG4717 379 AGVEDEEELRAALEQAEEYQELKEELEELE--EQLEELLGELEELLEALDEEELEEELEELEEELEELEEELEELREELA 456
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 568926913 631 ELKMHMSI--DKTTIQELNRCMAEKREE--QLFRQHEDAEVKKSTPEKNEKAISEETLQKVIELENRL 694
Cdd:COG4717 457 ELEAELEQleEDGELAELLQELEELKAElrELAEEWAALKLALELLEEAREEYREERLPPVLERASEY 524
|
|
| CCDC158 |
pfam15921 |
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ... |
172-826 |
3.14e-03 |
|
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.
Pssm-ID: 464943 [Multi-domain] Cd Length: 1112 Bit Score: 41.64 E-value: 3.14e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 172 KIQELEQTESVLKQELHDlvKLKTLVDEENAFLRKELCDLQKKFKDKSQEVKDAKECVQSKEEQNRLVIKNLEEENERLR 251
Cdd:pfam15921 239 RIFPVEDQLEALKSESQN--KIELLLQQHQDRIEQLISEHEVEITGLTEKASSARSQANSIQSQLEIIQEQARNQNSMYM 316
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 252 TRCTDLLNDLEKLRNQeahWRKEKHSVDTRVKVLEENLIEAKKEIESAQTKYNVVSQQLNNKQAELLQKDMDITLIRKEL 331
Cdd:pfam15921 317 RQLSDLESTVSQLRSE---LREAKRMYEDKIEELEKQLVLANSELTEARTERDQFSQESGNLDDQLQKLLADLHKREKEL 393
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 332 ----QELQNVYKQNSAHTAQQADLIQQLQALNMDTQKVlrnqedvhtaesmsyqklynelhmcfettksnEVMLRQSVVN 407
Cdd:pfam15921 394 slekEQNKRLWDRDTGNSITIDHLRRELDDRNMEVQRL--------------------------------EALLKAMKSE 441
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 408 LQGQLfqkEQENVKLKEKLEEsqgtapslsphdsdsshsgkapLSTLETLMISQKSEIEYLQKKLKVANEKLMANRSCDQ 487
Cdd:pfam15921 442 CQGQM---ERQMAAIQGKNES----------------------LEKVSSLTAQLESTKEMLRKVVEELTAKKMTLESSER 496
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 488 DFSEKGTEGKHKEPPVKRSRSlspkssfmgseELRKLKKaerKIENLEKTLQLKSQENDELRDAH-EKRKERLQMlhTNY 566
Cdd:pfam15921 497 TVSDLTASLQEKERAIEATNA-----------EITKLRS---RVDLKLQELQHLKNEGDHLRNVQtECEALKLQM--AEK 560
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 567 RAVKEQLKQWEEDSGMAESRQMKRA-----EPHQLRQEDSDAvwnelayfKRENQELMVQKMTLQDELDELKMHMS-IDK 640
Cdd:pfam15921 561 DKVIEILRQQIENMTQLVGQHGRTAgamqvEKAQLEKEINDR--------RLELQEFKILKDKKDAKIRELEARVSdLEL 632
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 641 TTIQELNRCMAEKREEQLFRQHEDA---EVKKSTPEKNEKAISEETLQKviELENRLKSFEKNSRKLKEESKRLKKENDF 717
Cdd:pfam15921 633 EKVKLVNAGSERLRAVKDIKQERDQllnEVKTSRNELNSLSEDYEVLKR--NFRNKSEEMETTTNKLKMQLKSAQSELEQ 710
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 718 LKSHLKhyqedseAREKELEQLLRVSKDVEHDKSELQTKITALETEVTTLRRQVTEAKALRG--KDEEVVCPEERAHRPT 795
Cdd:pfam15921 711 TRNTLK-------SMEGSDGHAMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEKHflKEEKNKLSQELSTVAT 783
|
650 660 670
....*....|....*....|....*....|...
gi 568926913 796 DKAK--SEMATTDVRARRCDCKTATTKVKFKAA 826
Cdd:pfam15921 784 EKNKmaGELEVLRSQERRLKEKVANMEVALDKA 816
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
528-783 |
3.22e-03 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 41.88 E-value: 3.22e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 528 ERKIENLEKTLQLKSQENDELRDAHEKRKERLQMLHTN---YRAVKEQLKQWEEDSGMAESRQMKRAEphQLRQEDSDAV 604
Cdd:pfam02463 169 RKKKEALKKLIEETENLAELIIDLEELKLQELKLKEQAkkaLEYYQLKEKLELEEEYLLYLDYLKLNE--ERIDLLQELL 246
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 605 WNELAYFKRENQELMVQKMTLQDELDELKMHMSIDKTTIQELNRCMAEKREEQLFRQHED------------AEVKKSTP 672
Cdd:pfam02463 247 RDEQEEIESSKQEIEKEEEKLAQVLKENKEEEKEKKLQEEELKLLAKEEEELKSELLKLErrkvddeeklkeSEKEKKKA 326
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 673 EKNEKAISEETLQKVIELENRLKSFEKNSRKLKEESKRLKKENDFLKSHLKHYQEDSEAREKELEQLLRVSKDVEHDKSE 752
Cdd:pfam02463 327 EKELKKEKEEIEELEKELKELEIKREAEEEEEEELEKLQEKLEQLEEELLAKKKLESERLSSAAKLKEEELELKSEEEKE 406
|
250 260 270
....*....|....*....|....*....|.
gi 568926913 753 LQTKITALETEVTTLRRQVTEAKALRGKDEE 783
Cdd:pfam02463 407 AQLLLELARQLEDLLKEEKKEELEILEEEEE 437
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
546-794 |
3.41e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 41.44 E-value: 3.41e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 546 DELRDAHEKRK--ERLQMLHTNYRAVKEQLkqweedsgmAESRQMKRAEPHQLRQEDSDAVWNELAYFKRENQELMVQKM 623
Cdd:COG4913 242 EALEDAREQIEllEPIRELAERYAAARERL---------AELEYLRAALRLWFAQRRLELLEAELEELRAELARLEAELE 312
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 624 TLQDELDElkmhmsidkttiqelnrcmAEKREEQLFRQHEDAEVKKSTPEKNEKAISEETLQkviELENRLKSFEKNSRK 703
Cdd:COG4913 313 RLEARLDA-------------------LREELDELEAQIRGNGGDRLEQLEREIERLERELE---ERERRRARLEALLAA 370
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 704 LKEESKRLKKENDFLKSHLKHYQEDSEAREKELEQ----LLRVSKDVEHDKSELQTKITALET-------EVTTLRRQVt 772
Cdd:COG4913 371 LGLPLPASAEEFAALRAEAAALLEALEEELEALEEalaeAEAALRDLRRELRELEAEIASLERrksnipaRLLALRDAL- 449
|
250 260 270
....*....|....*....|....*....|
gi 568926913 773 eAKALRGKDEEV--------VCPEERAHRP 794
Cdd:COG4913 450 -AEALGLDEAELpfvgelieVRPEEERWRG 478
|
|
| COG2433 |
COG2433 |
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only]; |
669-775 |
3.66e-03 |
|
Possible nuclease of RNase H fold, RuvC/YqgF family [General function prediction only];
Pssm-ID: 441980 [Multi-domain] Cd Length: 644 Bit Score: 41.38 E-value: 3.66e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 669 KSTPEKNEKAISEETlqkviELENRLKSFEKNSRKLKEESKRLKKENDFLKSHLkhyqEDSEAREKELEQLLRVSKDVEH 748
Cdd:COG2433 388 KELPEEEPEAEREKE-----HEERELTEEEEEIRRLEEQVERLEAEVEELEAEL----EEKDERIERLERELSEARSEER 458
|
90 100
....*....|....*....|....*..
gi 568926913 749 DKSELQTKITALETEVTTLRRQVTEAK 775
Cdd:COG2433 459 REIRKDREISRLDREIERLERELEEER 485
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
171-361 |
3.98e-03 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 41.15 E-value: 3.98e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 171 SKIQELEQTESVLKQELHDLV-KLKT---LVDEENAFLRKELCDLQKKFKDKSQEVKDAKECVQSKEEQnrlvIKNLEEE 246
Cdd:PHA02562 174 DKIRELNQQIQTLDMKIDHIQqQIKTynkNIEEQRKKNGENIARKQNKYDELVEEAKTIKAEIEELTDE----LLNLVMD 249
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 247 NErlrtrctDLLNDLEKLRNQEAHWRKEKHSVDTRVKVLEEN---------LIEAKKEIESAQTKYNVVSQQL---NNKQ 314
Cdd:PHA02562 250 IE-------DPSAALNKLNTAAAKIKSKIEQFQKVIKMYEKGgvcptctqqISEGPDRITKIKDKLKELQHSLeklDTAI 322
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 568926913 315 AELLQKDMDITLIRKELQELQNVY---KQNSAHTAQQA----DLIQQLQALNMD 361
Cdd:PHA02562 323 DELEEIMDEFNEQSKKLLELKNKIstnKQSLITLVDKAkkvkAAIEELQAEFVD 376
|
|
| PspC_subgroup_1 |
NF033838 |
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ... |
670-794 |
4.73e-03 |
|
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.
Pssm-ID: 468201 [Multi-domain] Cd Length: 684 Bit Score: 41.15 E-value: 4.73e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 670 STPEKNEK-------AISEETL--------QKVIELENRLKSFEKNSRKLKEESKRLKKENDFLKSHLKHYQEDSEAREK 734
Cdd:NF033838 274 ATPDKKENdakssdsSVGEETLpspslkpeKKVAEAEKKVEEAKKKAKDQKEEDRRNYPTNTYKTLELEIAESDVKVKEA 353
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 568926913 735 ELEQLLRVSKDV--EHDKSELQTKITALETEVTTLR-----RQVTEAKALRGKDEEVVCPEERAHRP 794
Cdd:NF033838 354 ELELVKEEAKEPrnEEKIKQAKAKVESKKAEATRLEkiktdRKKAEEEAKRKAAEEDKVKEKPAEQP 420
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
519-720 |
6.34e-03 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 40.79 E-value: 6.34e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 519 EELRKLKKAERKIENLEKTLQLKSQENDELRDAHEKRKERLQMLHTNYRAVKEQLKQWEEDSGMAESR-----------Q 587
Cdd:PRK02224 499 ERAEDLVEAEDRIERLEERREDLEELIAERRETIEEKRERAEELRERAAELEAEAEEKREAAAEAEEEaeeareevaelN 578
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 588 MKRAEPHQLRQ--EDSDAVWNELAYFKRENQELMVQKMTLQDELDELKMHMSIDKTTIQELNRCMAEKREEQLFRQHEDA 665
Cdd:PRK02224 579 SKLAELKERIEslERIRTLLAAIADAEDEIERLREKREALAELNDERRERLAEKRERKRELEAEFDEARIEEAREDKERA 658
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 568926913 666 E--VKKSTPEKNEKAISEETLQKVI-ELENRLKSFEknsrKLKEESKRLKKENDFLKS 720
Cdd:PRK02224 659 EeyLEQVEEKLDELREERDDLQAEIgAVENELEELE----ELRERREALENRVEALEA 712
|
|
| Macoilin |
pfam09726 |
Macoilin family; The Macoilin proteins has an N-terminal portion that is composed of 5 ... |
171-435 |
7.85e-03 |
|
Macoilin family; The Macoilin proteins has an N-terminal portion that is composed of 5 trasnmembrane helices, followed by a C-terminal coiled-coil region. Macoilin is a highly conserved protein present in eukaryotes. Macoilin appears to be found in the ER and be involved in the function of neurons.
Pssm-ID: 462859 [Multi-domain] Cd Length: 670 Bit Score: 40.22 E-value: 7.85e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 171 SKIQELEQTESVLKQELHDLVKLKTLVDEENAFLRKELCDLQKKFKDKSQEVKDAKECVQSKEeqnrlviKNLEEENERL 250
Cdd:pfam09726 409 AELQASRQTEQELRSQISSLTSLERSLKSELGQLRQENDLLQTKLHNAVSAKQKDKQTVQQLE-------KRLKAEQEAR 481
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 251 RTrctdllndLEKLRNQEAHWRKEKHSVDTRVKVLEENlieAKKE-IESAQTKYNVVSQQLNNKQAELLQKDMDITLIRK 329
Cdd:pfam09726 482 AS--------AEKQLAEEKKRKKEEEATAARAVALAAA---SRGEcTESLKQRKRELESEIKKLTHDIKLKEEQIRELEI 550
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 330 ELQELQNvYKQNSAHTAQqadLIQQLQALNMDTQKVlrnqEDVHTAESMSYQKLYNELHmcfETTKSNEVmlrqsvvnLQ 409
Cdd:pfam09726 551 KVQELRK-YKESEKDTEV---LMSALSAMQDKNQHL----ENSLSAETRIKLDLFSALG---DAKRQLEI--------AQ 611
|
250 260
....*....|....*....|....*.
gi 568926913 410 GQLFQKEQENVKLKEKLEESQGTAPS 435
Cdd:pfam09726 612 GQIYQKDQEIKDLKQKIAEVMAVMPS 637
|
|
| DUF3584 |
pfam12128 |
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. ... |
522-789 |
7.85e-03 |
|
Protein of unknown function (DUF3584); This protein is found in bacteria and eukaryotes. Proteins in this family are typically between 943 to 1234 amino acids in length. This family contains a P-loop motif suggesting it is a nucleotide binding protein. It may be involved in replication.
Pssm-ID: 432349 [Multi-domain] Cd Length: 1191 Bit Score: 40.59 E-value: 7.85e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 522 RKLKKAERKIENLEKTL--------QLKSQENDELRDAHEKRKERLQMLHTNYRAVKEQLKQW-EEDSGMAESRQMKRAE 592
Cdd:pfam12128 639 REETFARTALKNARLDLrrlfdekqSEKDKKNKALAERKDSANERLNSLEAQLKQLDKKHQAWlEEQKEQKREARTEKQA 718
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 593 PHQLRQEDSDAvwnELAYFKRENQELMVQKMTLQDELDElKMHMSIDKTTIQELNRCMAEKREEQLFRQHEDAEVKKSTP 672
Cdd:pfam12128 719 YWQVVEGALDA---QLALLKAAIAARRSGAKAELKALET-WYKRDLASLGVDPDVIAKLKREIRTLERKIERIAVRRQEV 794
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 673 EKNEKAISEETLQKVIELENRLKSFEKNSRKLKEESKRLkkendflkshlkhyQEDSEAREKELEQLLRVSKDVEHDKSE 752
Cdd:pfam12128 795 LRYFDWYQETWLQRRPRLATQLSNIERAISELQQQLARL--------------IADTKLRRAKLEMERKASEKQQVRLSE 860
|
250 260 270
....*....|....*....|....*....|....*..
gi 568926913 753 LQTKITALETEVTTLRRQVTEAKALRGKDEEVVCPEE 789
Cdd:pfam12128 861 NLRGLRCEMSKLATLKEDANSEQAQGSIGERLAQLED 897
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
131-299 |
8.10e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 40.28 E-value: 8.10e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 131 RRLQATNPDLTQTVSLVVEREKQKSEAKDRKV---LEILQVKDSKIQELEQTESVLKQELHDLVKLKTLVDEENAFLRKE 207
Cdd:COG4913 295 AELEELRAELARLEAELERLEARLDALREELDeleAQIRGNGGDRLEQLEREIERLERELEERERRRARLEALLAALGLP 374
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 568926913 208 LCDLQKKFKDKSQEVKDAKEcvqskeeqnrlvikNLEEENERLRTRCTDLLNDLEKLRNQEAHWRKEKHSVDTRVKVLEE 287
Cdd:COG4913 375 LPASAEEFAALRAEAAALLE--------------ALEEELEALEEALAEAEAALRDLRRELRELEAEIASLERRKSNIPA 440
|
170
....*....|..
gi 568926913 288 NLIEAKKEIESA 299
Cdd:COG4913 441 RLLALRDALAEA 452
|
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