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Conserved domains on  [gi|578798982|ref|XP_006710652|]
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G-protein-signaling modulator 2 isoform X2 [Homo sapiens]

Protein Classification

TPR and TPR_12 domain-containing protein; tetratricopeptide repeat protein( domain architecture ID 11421212)

protein containing domains TPR, TPR_12, and GoLoco; tetratricopeptide repeat (TPR) protein such as kinesin light chain, which mediates the selective binding of kinesin to its cargo

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
46-316 1.07e-19

Tetratricopeptide (TPR) repeat [General function prediction only];


:

Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 88.91  E-value: 1.07e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982  46 YSQLGNAYFYLHDYAKALEYHHHDLTLARtigdqlGEAKASGNLGNTLKVLGNFDEAIVCCQRHLDISRELndkvgeARA 125
Cdd:COG0457   11 YNNLGLAYRRLGRYEEAIEDYEKALELDP------DDAEALYNLGLAYLRLGRYEEALADYEQALELDPDD------AEA 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982 126 LYNLGNVYHAKGKsfgcpgpqdvgefpeevrdaLQAAVDFYEEnlslvtALGDRAAQGRAFGNLGNTHYLLGNFRDAVIA 205
Cdd:COG0457   79 LNNLGLALQALGR--------------------YEEALEDYDK------ALELDPDDAEALYNLGLALLELGRYDEAIEA 132

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982 206 HEQRLLIAKEFGDkaaerrAYSNLGNAYIFLGEFETASEYYKKtlLLARQLKDRAVEAQSCYSLGNTYTLLQDYEKAIDY 285
Cdd:COG0457  133 YERALELDPDDAD------ALYNLGIALEKLGRYEEALELLEK--LEAAALAALLAAALGEAALALAAAEVLLALLLALE 204

                        250       260       270
                 ....*....|....*....|....*....|.
gi 578798982 286 HLKHLAIAQELNDRIGEGRACWSLGNAYTAL 316
Cdd:COG0457  205 QALRKKLAILTLAALAELLLLALALLLALRL 235
GoLoco pfam02188
GoLoco motif;
471-492 3.59e-07

GoLoco motif;


:

Pssm-ID: 460481  Cd Length: 22  Bit Score: 46.64  E-value: 3.59e-07
                          10        20
                  ....*....|....*....|..
gi 578798982  471 EGFFDLLSRFQSNRMDDQRCCL 492
Cdd:pfam02188   1 EDFFDLLARVQSSRLDDQRCSL 22
GoLoco smart00390
LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins
 575-597 1.68e-06

LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins


:

Pssm-ID: 214645  Cd Length: 23  Bit Score: 44.80  E-value: 1.68e-06
                           10        20
                   ....*....|....*....|...
gi 578798982   575 DEDFFDILVKCQGSRLDDQRCAP 597
Cdd:smart00390   1 DEDLFDLLLRMQSSRMDDQRCEL 23
GoLoco pfam02188
GoLoco motif;
610-631 3.72e-06

GoLoco motif;


:

Pssm-ID: 460481  Cd Length: 22  Bit Score: 43.56  E-value: 3.72e-06
                          10        20
                  ....*....|....*....|..
gi 578798982  610 EDFFSLILRSQGKRMDEQRVLL 631
Cdd:pfam02188   1 EDFFDLLARVQSSRLDDQRCSL 22
GoLoco pfam02188
GoLoco motif;
526-547 1.39e-05

GoLoco motif;


:

Pssm-ID: 460481  Cd Length: 22  Bit Score: 42.02  E-value: 1.39e-05
                          10        20
                  ....*....|....*....|..
gi 578798982  526 DEFLDLLASSQSRRLDDQRASF 547
Cdd:pfam02188   1 EDFFDLLARVQSSRLDDQRCSL 22
TPR_7 pfam13176
Tetratricopeptide repeat;
305-340 2.20e-03

Tetratricopeptide repeat;


:

Pssm-ID: 433012 [Multi-domain]  Cd Length: 36  Bit Score: 35.98  E-value: 2.20e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 578798982  305 ACWSLGNAYTALGNHDQAMHFAEKHLEISREVGDKS 340
Cdd:pfam13176   1 ALLNLGRIYRKLGDYDEAISLYEQALALAKDPYDRE 36
 
Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
46-316 1.07e-19

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 88.91  E-value: 1.07e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982  46 YSQLGNAYFYLHDYAKALEYHHHDLTLARtigdqlGEAKASGNLGNTLKVLGNFDEAIVCCQRHLDISRELndkvgeARA 125
Cdd:COG0457   11 YNNLGLAYRRLGRYEEAIEDYEKALELDP------DDAEALYNLGLAYLRLGRYEEALADYEQALELDPDD------AEA 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982 126 LYNLGNVYHAKGKsfgcpgpqdvgefpeevrdaLQAAVDFYEEnlslvtALGDRAAQGRAFGNLGNTHYLLGNFRDAVIA 205
Cdd:COG0457   79 LNNLGLALQALGR--------------------YEEALEDYDK------ALELDPDDAEALYNLGLALLELGRYDEAIEA 132

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982 206 HEQRLLIAKEFGDkaaerrAYSNLGNAYIFLGEFETASEYYKKtlLLARQLKDRAVEAQSCYSLGNTYTLLQDYEKAIDY 285
Cdd:COG0457  133 YERALELDPDDAD------ALYNLGIALEKLGRYEEALELLEK--LEAAALAALLAAALGEAALALAAAEVLLALLLALE 204

                        250       260       270
                 ....*....|....*....|....*....|.
gi 578798982 286 HLKHLAIAQELNDRIGEGRACWSLGNAYTAL 316
Cdd:COG0457  205 QALRKKLAILTLAALAELLLLALALLLALRL 235
TPR_12 pfam13424
Tetratricopeptide repeat;
224-295 3.28e-09

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 53.93  E-value: 3.28e-09
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 578798982  224 RAYSNLGNAYIFLGEFETASEYYKKTLLLARQL--KDRAVEAQSCYSLGNTYTLLQDYEKAIDYHLKHLAIAQE 295
Cdd:pfam13424   4 TALNNLAAVLRRLGRYDEALELLEKALEIARRLlgPDHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
GoLoco pfam02188
GoLoco motif;
471-492 3.59e-07

GoLoco motif;


Pssm-ID: 460481  Cd Length: 22  Bit Score: 46.64  E-value: 3.59e-07
                          10        20
                  ....*....|....*....|..
gi 578798982  471 EGFFDLLSRFQSNRMDDQRCCL 492
Cdd:pfam02188   1 EDFFDLLARVQSSRLDDQRCSL 22
GoLoco smart00390
LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins
 470-492 4.80e-07

LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins


Pssm-ID: 214645  Cd Length: 23  Bit Score: 46.34  E-value: 4.80e-07
                           10        20
                   ....*....|....*....|...
gi 578798982   470 DEGFFDLLSRFQSNRMDDQRCCL 492
Cdd:smart00390   1 DEDLFDLLLRMQSSRMDDQRCEL 23
GoLoco smart00390
LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins
 575-597 1.68e-06

LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins


Pssm-ID: 214645  Cd Length: 23  Bit Score: 44.80  E-value: 1.68e-06
                           10        20
                   ....*....|....*....|...
gi 578798982   575 DEDFFDILVKCQGSRLDDQRCAP 597
Cdd:smart00390   1 DEDLFDLLLRMQSSRMDDQRCEL 23
GoLoco pfam02188
GoLoco motif;
610-631 3.72e-06

GoLoco motif;


Pssm-ID: 460481  Cd Length: 22  Bit Score: 43.56  E-value: 3.72e-06
                          10        20
                  ....*....|....*....|..
gi 578798982  610 EDFFSLILRSQGKRMDEQRVLL 631
Cdd:pfam02188   1 EDFFDLLARVQSSRLDDQRCSL 22
GoLoco pfam02188
GoLoco motif;
576-595 3.86e-06

GoLoco motif;


Pssm-ID: 460481  Cd Length: 22  Bit Score: 43.56  E-value: 3.86e-06
                          10        20
                  ....*....|....*....|
gi 578798982  576 EDFFDILVKCQGSRLDDQRC 595
Cdd:pfam02188   1 EDFFDLLARVQSSRLDDQRC 20
GoLoco smart00390
LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins
 609-631 6.42e-06

LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins


Pssm-ID: 214645  Cd Length: 23  Bit Score: 42.87  E-value: 6.42e-06
                           10        20
                   ....*....|....*....|...
gi 578798982   609 DEDFFSLILRSQGKRMDEQRVLL 631
Cdd:smart00390   1 DEDLFDLLLRMQSSRMDDQRCEL 23
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 69-388 1.14e-05

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 48.76  E-value: 1.14e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982  69 DLTLARTIGDQLGEA-------------KASGNLGNTLKVLGNFDEAivccqrhldisRELNDKV-GEARALYNLGNVYH 134
Cdd:NF040586 407 DYESARDLAERALERwrerlgpddrqtlRLRFHLANALRSLGRYEEA-----------RELDEDTlERQRRVLGLGEDHP 475

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982 135 ----AKGkSFGcpgpQD---VGEFPE---EVRDALQAAVDFYEENlslvtalgDRAAQgRAFGNLGNTHYLLGNFRDAVI 204
Cdd:NF040586 476 htlmTAG-GLG----ADlraLGRFREaleLDEETLERHRRVFGED--------HPRTL-RAANNLAVSLRLLGDYREALE 541

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982 205 AHEQRLLIAKE-FG-DKAAERRAYSNLGNAYIFLGEF-------ETASEYYKKTLLLA------RQLKDRAVeaqSCYSL 269
Cdd:NF040586 542 LDREVLRRRRRvLGpDHPRTLLSANNLARDLRELGRYaealdllEEALERYREVLGGPdhpdtlRAAKSLAV---ALRRA 618

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982 270 GntytllqDYEKAidyhlkhLAIAQE----LNDRIGEG----RAC-WSLGNAYTALGNHDQAMHFAEKHLEISREVGdks 340
Cdd:NF040586 619 G-------RLEEA-------LELAEDtyerYRRRFGPDhpdtLAAaLSLANDLRALGDADEARELAREVLDRYRRVL--- 681

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....
gi 578798982 341 GE-----LTARLNLSDLQMVLGLSYstnnsimsENTEID-SSLNGVRPKLGRRH 388
Cdd:NF040586 682 GEdhpftLACRNNLAVLLRALGDPE--------EARELAeAALEGLRERLGPDH 727
GoLoco pfam02188
GoLoco motif;
526-547 1.39e-05

GoLoco motif;


Pssm-ID: 460481  Cd Length: 22  Bit Score: 42.02  E-value: 1.39e-05
                          10        20
                  ....*....|....*....|..
gi 578798982  526 DEFLDLLASSQSRRLDDQRASF 547
Cdd:pfam02188   1 EDFFDLLARVQSSRLDDQRCSL 22
GoLoco smart00390
LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins
 525-547 5.99e-05

LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins


Pssm-ID: 214645  Cd Length: 23  Bit Score: 40.18  E-value: 5.99e-05
                           10        20
                   ....*....|....*....|...
gi 578798982   525 TDEFLDLLASSQSRRLDDQRASF 547
Cdd:smart00390   1 DEDLFDLLLRMQSSRMDDQRCEL 23
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 263-295 5.15e-04

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 37.81  E-value: 5.15e-04
                           10        20        30
                   ....*....|....*....|....*....|...
gi 578798982   263 AQSCYSLGNTYTLLQDYEKAIDYHLKHLAIAQE 295
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPN 33
TPR_7 pfam13176
Tetratricopeptide repeat;
305-340 2.20e-03

Tetratricopeptide repeat;


Pssm-ID: 433012 [Multi-domain]  Cd Length: 36  Bit Score: 35.98  E-value: 2.20e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 578798982  305 ACWSLGNAYTALGNHDQAMHFAEKHLEISREVGDKS 340
Cdd:pfam13176   1 ALLNLGRIYRKLGDYDEAISLYEQALALAKDPYDRE 36
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 304-335 9.77e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 34.34  E-value: 9.77e-03
                           10        20        30
                   ....*....|....*....|....*....|..
gi 578798982   304 RACWSLGNAYTALGNHDQAMHFAEKHLEISRE 335
Cdd:smart00028   2 EALYNLGNAYLKLGDYDEALEYYEKALELDPN 33
 
Name Accession Description Interval E-value
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
46-316 1.07e-19

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 88.91  E-value: 1.07e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982  46 YSQLGNAYFYLHDYAKALEYHHHDLTLARtigdqlGEAKASGNLGNTLKVLGNFDEAIVCCQRHLDISRELndkvgeARA 125
Cdd:COG0457   11 YNNLGLAYRRLGRYEEAIEDYEKALELDP------DDAEALYNLGLAYLRLGRYEEALADYEQALELDPDD------AEA 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982 126 LYNLGNVYHAKGKsfgcpgpqdvgefpeevrdaLQAAVDFYEEnlslvtALGDRAAQGRAFGNLGNTHYLLGNFRDAVIA 205
Cdd:COG0457   79 LNNLGLALQALGR--------------------YEEALEDYDK------ALELDPDDAEALYNLGLALLELGRYDEAIEA 132

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982 206 HEQRLLIAKEFGDkaaerrAYSNLGNAYIFLGEFETASEYYKKtlLLARQLKDRAVEAQSCYSLGNTYTLLQDYEKAIDY 285
Cdd:COG0457  133 YERALELDPDDAD------ALYNLGIALEKLGRYEEALELLEK--LEAAALAALLAAALGEAALALAAAEVLLALLLALE 204

                        250       260       270
                 ....*....|....*....|....*....|.
gi 578798982 286 HLKHLAIAQELNDRIGEGRACWSLGNAYTAL 316
Cdd:COG0457  205 QALRKKLAILTLAALAELLLLALALLLALRL 235
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
82-349 3.41e-19

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 87.37  E-value: 3.41e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982  82 EAKASGNLGNTLKVLGNFDEAIVCCQRHLDISRElndkvgEARALYNLGNVYHAKGKsfgcpgpqdvgefpeevrdaLQA 161
Cdd:COG0457    7 DAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPD------DAEALYNLGLAYLRLGR--------------------YEE 60

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982 162 AVDFYEEnlslvtALGDRAAQGRAFGNLGNTHYLLGNFRDAVIAHEQRLLIAKEFGDkaaerrAYSNLGNAYIFLGEFET 241
Cdd:COG0457   61 ALADYEQ------ALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAE------ALYNLGLALLELGRYDE 128

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982 242 ASEYYKKTLLLARQLkdraveAQSCYSLGNTYTLLQDYEKAIDYHLKhlAIAQELNDRIGEGRACWSLGNAYTALGNHDQ 321
Cdd:COG0457  129 AIEAYERALELDPDD------ADALYNLGIALEKLGRYEEALELLEK--LEAAALAALLAAALGEAALALAAAEVLLALL 200

                        250       260
                 ....*....|....*....|....*...
gi 578798982 322 AMHFAEKHLEISREVGDKSGELTARLNL 349
Cdd:COG0457  201 LALEQALRKKLAILTLAALAELLLLALA 228
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 48-332 2.09e-14

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 74.00  E-value: 2.09e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982  48 QLGNAYFYLHDYAKALEYhhhdltLARTIGDQLGEAKASGNLGNTLKVLGNFDEAIVCCQRHLDISRElndkvgEARALY 127
Cdd:COG2956   13 FKGLNYLLNGQPDKAIDL------LEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPD------RAEALL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982 128 NLGNVYHAKGKsfgcpgpqdvgefpeevrdaLQAAVDFYEEnlslvtALGDRAAQGRAFGNLGNTHYLLGNFRDAVIAHE 207
Cdd:COG2956   81 ELAQDYLKAGL--------------------LDRAEELLEK------LLELDPDDAEALRLLAEIYEQEGDWEKAIEVLE 134

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982 208 QrllIAKEFGDKAaerRAYSNLGNAYIFLGEFETASEYYKKtlllARQLKDRAVEAQscYSLGNTYTLLQDYEKAIdyhl 287
Cdd:COG2956  135 R---LLKLGPENA---HAYCELAELYLEQGDYDEAIEALEK----ALKLDPDCARAL--LLLAELYLEQGDYEEAI---- 198

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*
gi 578798982 288 KHLAIAQELNDRIGEGRAcwSLGNAYTALGNHDQAMHFAEKHLEI 332
Cdd:COG2956  199 AALERALEQDPDYLPALP--RLAELYEKLGDPEEALELLRKALEL 241
COG3899 COG3899
Predicted ATPase [General function prediction only];
156-310 3.33e-12

Predicted ATPase [General function prediction only];


Pssm-ID: 443106 [Multi-domain]  Cd Length: 1244  Bit Score: 69.89  E-value: 3.33e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982  156 RDALQAAVDFYEENLSLVTALGDRAAQGRAFGNLGNTHYLLGNF-------RDAVIAHEQRLLIAKEFGDKAAERRAYSN 228
Cdd:COG3899   718 RGAYAEALRYLERALELLPPDPEEEYRLALLLELAEALYLAGRFeeaeallERALAARALAALAALRHGNPPASARAYAN 797

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982  229 LGnaYIFLGEFETASEYYKKTLLLARQLKDRAVEAQSCYSLGNTYTLLQDYEKAIDYHLKHLAIAQELNDRIGEGRACWS 308
Cdd:COG3899   798 LG--LLLLGDYEEAYEFGELALALAERLGDRRLEARALFNLGFILHWLGPLREALELLREALEAGLETGDAALALLALAA 875


                  ..
gi 578798982  309 LG 310
Cdd:COG3899   876 AA 877
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 10-331 2.03e-11

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 65.14  E-value: 2.03e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982  10 LEGERLCKSGDCRAGVSFFEAAVQVGTEDLKTlsaiYSQLGNAYFYLHDYAKALEYHHHDLTLARTigdqlgEAKASGNL 89
Cdd:COG2956   13 FKGLNYLLNGQPDKAIDLLEEALELDPETVEA----HLALGNLYRRRGEYDRAIRIHQKLLERDPD------RAEALLEL 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982  90 GNTLKVLGNFDEAIVCCQRHLDISRElndkvgEARALYNLGNVYHAKGKsfgcpgpqdvgefpeevrdaLQAAVDFYEEn 169
Cdd:COG2956   83 AQDYLKAGLLDRAEELLEKLLELDPD------DAEALRLLAEIYEQEGD--------------------WEKAIEVLER- 135

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982 170 lslvtALGDRAAQGRAFGNLGNTHYLLGNFRDAVIAHEQRLLIAKEFgdkaaeRRAYSNLGNAYIFLGEFETASEYYKKT 249
Cdd:COG2956  136 -----LLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDC------ARALLLLAELYLEQGDYEEAIAALERA 204

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982 250 LllarQLKDRAVEAQscYSLGNTYTLLQDYEKAIDYHLKHLAIAQELNDRIgegracwSLGNAYTALGNHDQAMHFAEKH 329
Cdd:COG2956  205 L----EQDPDYLPAL--PRLAELYEKLGDPEEALELLRKALELDPSDDLLL-------ALADLLERKEGLEAALALLERQ 271


                 ..
gi 578798982 330 LE 331
Cdd:COG2956  272 LR 273
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 37-255 4.06e-11

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 66.17  E-value: 4.06e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982  37 EDLKTLSAIYSQLGNAYFYLHDYAKALEYHHHDLTLARTigdqlgEAKASGNLGNTLKVLGNFDEAIVCCQRHLDIsrel 116
Cdd:COG3914   72 AALLLLAALLELAALLLQALGRYEEALALYRRALALNPD------NAEALFNLGNLLLALGRLEEALAALRRALAL---- 141

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982 117 ndKVGEARALYNLGNVYHAKGKsfgcpgpqdvgefPEEVRDALQAAVDFYEENLslvtalgdraaqgRAFGNLGNTHYLL 196
Cdd:COG3914  142 --NPDFAEAYLNLGEALRRLGR-------------LEEAIAALRRALELDPDNA-------------EALNNLGNALQDL 193

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 578798982 197 GNFRDAVIAHEQRLLIAKEFgdkaaeRRAYSNLGNAYIFLGEFETASEYYKKTLLLARQ 255
Cdd:COG3914  194 GRLEEAIAAYRRALELDPDN------ADAHSNLLFALRQACDWEVYDRFEELLAALARG 246
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 156-332 3.51e-10

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 63.09  E-value: 3.51e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982 156 RDALQAAVDFYEENLSLVTALGDRAAQGRAFGNLGNTHYLLGNFRDAVIAHEQRLLIAKEFGDkaaerrAYSNLGNAYIF 235
Cdd:COG3914   51 LAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGRYEEALALYRRALALNPDNAE------ALFNLGNLLLA 124

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982 236 LGEFETASEYYKKtlllARQLKDRAVEAqsCYSLGNTYTLLQDYEKAIDYHLKHLAIAQELNDrigegrACWSLGNAYTA 315
Cdd:COG3914  125 LGRLEEALAALRR----ALALNPDFAEA--YLNLGEALRRLGRLEEAIAALRRALELDPDNAE------ALNNLGNALQD 192

                        170
                 ....*....|....*..
gi 578798982 316 LGNHDQAMHFAEKHLEI 332
Cdd:COG3914  193 LGRLEEAIAAYRRALEL 209
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 180-333 3.21e-09

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 55.58  E-value: 3.21e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982 180 AAQGRAFGNLGNTHYLLGNFRDAVIAHEQRLLIAKEFGDkaaerrAYSNLGNAYIFLGEFETASEYYKKtlllARQLKDR 259
Cdd:COG4783    1 AACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPE------AFALLGEILLQLGDLDEAIVLLHE----ALELDPD 70

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 578798982 260 AVEAQscYSLGNTYTLLQDYEKAIDYHLKHLAIAQElndrigEGRACWSLGNAYTALGNHDQAMHFAEKHLEIS 333
Cdd:COG4783   71 EPEAR--LNLGLALLKAGDYDEALALLEKALKLDPE------HPEAYLRLARAYRALGRPDEAIAALEKALELD 136
TPR_12 pfam13424
Tetratricopeptide repeat;
224-295 3.28e-09

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 53.93  E-value: 3.28e-09
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 578798982  224 RAYSNLGNAYIFLGEFETASEYYKKTLLLARQL--KDRAVEAQSCYSLGNTYTLLQDYEKAIDYHLKHLAIAQE 295
Cdd:pfam13424   4 TALNNLAAVLRRLGRYDEALELLEKALEIARRLlgPDHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 152-357 1.05e-08

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 58.47  E-value: 1.05e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982 152 PEEVRDALQAAVDFYEENLSlvtALGDRAAQGRAFGNLGNTHYLLGNFRDAVIAHEQRLLIAKEFGDKAAERRAYSNLGN 231
Cdd:COG3914   10 AALAAAALLAAAAAAELALA---AELEAAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAAL 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982 232 AYIFLGEFETASEYYKKTLLLARQlkdravEAQSCYSLGNTYTLLQDYEKAIDYHLKHLAIAQELndrigeGRACWSLGN 311
Cdd:COG3914   87 LLQALGRYEEALALYRRALALNPD------NAEALFNLGNLLLALGRLEEALAALRRALALNPDF------AEAYLNLGE 154

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 578798982 312 AYTALGNHDQAMHFAEKHLEIsrevgdKSGELTARLNLSDLQMVLG 357
Cdd:COG3914  155 ALRRLGRLEEAIAALRRALEL------DPDNAEALNNLGNALQDLG 194
TPR_12 pfam13424
Tetratricopeptide repeat;
267-335 2.27e-08

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 51.23  E-value: 2.27e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 578798982  267 YSLGNTYTLLQDYEKAIDYHLKHLAIAQEL--NDRIGEGRACWSLGNAYTALGNHDQAMHFAEKHLEISRE 335
Cdd:pfam13424   7 NNLAAVLRRLGRYDEALELLEKALEIARRLlgPDHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 159-293 3.21e-08

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 56.93  E-value: 3.21e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982 159 LQAAVDFYEEnlslvtALGDRAAQGRAFGNLGNTHYLLGNFRDAVIAHEQRLLIAKEFGDkaaerrAYSNLGNAYIFLGE 238
Cdd:COG3914   94 YEEALALYRR------ALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAE------AYLNLGEALRRLGR 161

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 578798982 239 FETASEYYKKtlllARQLKDRAVEAQscYSLGNTYTLLQDYEKAIDYHLKHLAIA 293
Cdd:COG3914  162 LEEAIAALRR----ALELDPDNAEAL--NNLGNALQDLGRLEEAIAAYRRALELD 210
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
12-226 9.57e-08

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 53.47  E-value: 9.57e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982  12 GERLCKSGDCRAGVSFFEAAVQVGTEDlktlSAIYSQLGNAYFYLHDYAKALEYHHHDLTLARTigdqlgEAKASGNLGN 91
Cdd:COG0457   49 GLAYLRLGRYEEALADYEQALELDPDD----AEALNNLGLALQALGRYEEALEDYDKALELDPD------DAEALYNLGL 118

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982  92 TLKVLGNFDEAIVCCQRHLDISRELndkvgeARALYNLGNVYHAKGKSfgcPGPQDVGEFPEEVRDALQAAVDFYEENLS 171
Cdd:COG0457  119 ALLELGRYDEAIEAYERALELDPDD------ADALYNLGIALEKLGRY---EEALELLEKLEAAALAALLAAALGEAALA 189

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 578798982 172 LVTALGDRAAQGRAFGNLGNTHYLLGNFRDAVIAHEQRLLIAKEFGDKAAERRAY 226
Cdd:COG0457  190 LAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLALRLAALALYQYR 244
COG3899 COG3899
Predicted ATPase [General function prediction only];
57-322 1.06e-07

Predicted ATPase [General function prediction only];


Pssm-ID: 443106 [Multi-domain]  Cd Length: 1244  Bit Score: 55.25  E-value: 1.06e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982   57 HDYAKALEYHHHDLTLARTIGDQLGEAKASGNLGNTLKVLGNFDEAIVCCQRHLDI-------SRELNDKVGEARALYNL 129
Cdd:COG3899   719 GAYAEALRYLERALELLPPDPEEEYRLALLLELAEALYLAGRFEEAEALLERALAAralaalaALRHGNPPASARAYANL 798

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982  130 GNVYhakgksfgcpgpqdvgefpeevRDALQAAVDFYEENLSLVTALGDRAAQGRAFGNLGNTHYLLGNFRDAVIAHEQR 209
Cdd:COG3899   799 GLLL----------------------LGDYEEAYEFGELALALAERLGDRRLEARALFNLGFILHWLGPLREALELLREA 856

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982  210 LLIAKEFGDKAAERRAYSNLGNAYIFLGEFETASEYYKKTLLLAR------QLKDRAVEAQSCYSLGNTYTLLQDYEKAI 283
Cdd:COG3899   857 LEAGLETGDAALALLALAAAAAAAAAAAALAAAAAAAARLLAAAAaalaaaAAAAALAAAELARLAAAAAAAAALALAAA 936

                         250       260       270
                  ....*....|....*....|....*....|....*....
gi 578798982  284 DYHLKHLAIAQELNDRIGEGRACWSLGNAYTALGNHDQA 322
Cdd:COG3899   937 AAAAAAAALAAAAAAAALAAALALAAAAAAAAAAALAAA 975
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 172-285 3.50e-07

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 49.62  E-value: 3.50e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982 172 LVTALGDRAAQ----GRAFGNLGNTHYLLGNFRDAVIAHEQRLLIAKEFGDkaaerrAYSNLGNAYIFLGEFETASEYYK 247
Cdd:COG4235    2 AIARLRQALAAnpndAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNAD------ALLDLAEALLAAGDTEEAEELLE 75

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 578798982 248 KtlllARQLKDRAVEAQscYSLGNTYTLLQDYEKAIDY 285
Cdd:COG4235   76 R----ALALDPDNPEAL--YLLGLAAFQQGDYAEAIAA 107
GoLoco pfam02188
GoLoco motif;
471-492 3.59e-07

GoLoco motif;


Pssm-ID: 460481  Cd Length: 22  Bit Score: 46.64  E-value: 3.59e-07
                          10        20
                  ....*....|....*....|..
gi 578798982  471 EGFFDLLSRFQSNRMDDQRCCL 492
Cdd:pfam02188   1 EDFFDLLARVQSSRLDDQRCSL 22
TPR_12 pfam13424
Tetratricopeptide repeat;
184-255 3.91e-07

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 47.77  E-value: 3.91e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 578798982  184 RAFGNLGNTHYLLGNFRDAVIAHEQRLLIAKEF--GDKAAERRAYSNLGNAYIFLGEFETASEYYKKTLLLARQ 255
Cdd:pfam13424   4 TALNNLAAVLRRLGRYDEALELLEKALEIARRLlgPDHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 121-295 4.04e-07

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 49.81  E-value: 4.04e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982 121 GEARALYNLGNVYHAKGKsfgcpgpqdvgefPEEVRDALQAAVDFYEENLslvtalgdraaqgRAFGNLGNTHYLLGNFR 200
Cdd:COG4783    2 ACAEALYALAQALLLAGD-------------YDEAEALLEKALELDPDNP-------------EAFALLGEILLQLGDLD 55

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982 201 DAVIAHEQRLLIAKEfgdkaaERRAYSNLGNAYIFLGEFETASEYYKKTLLLARQlkdravEAQSCYSLGNTYTLLQDYE 280
Cdd:COG4783   56 EAIVLLHEALELDPD------EPEARLNLGLALLKAGDYDEALALLEKALKLDPE------HPEAYLRLARAYRALGRPD 123

                        170
                 ....*....|....*
gi 578798982 281 KAIDYHLKHLAIAQE 295
Cdd:COG4783  124 EAIAALEKALELDPD 138
GoLoco smart00390
LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins
 470-492 4.80e-07

LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins


Pssm-ID: 214645  Cd Length: 23  Bit Score: 46.34  E-value: 4.80e-07
                           10        20
                   ....*....|....*....|...
gi 578798982   470 DEGFFDLLSRFQSNRMDDQRCCL 492
Cdd:smart00390   1 DEDLFDLLLRMQSSRMDDQRCEL 23
TPR_12 pfam13424
Tetratricopeptide repeat;
83-168 6.70e-07

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 47.38  E-value: 6.70e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982   83 AKASGNLGNTLKVLGNFDEAIVCCQRHLDISREL--NDKVGEARALYNLGNVYHAKGKsfgcpgpqdvgefPEEVRDALQ 160
Cdd:pfam13424   3 ATALNNLAAVLRRLGRYDEALELLEKALEIARRLlgPDHPLTATTLLNLGRLYLELGR-------------YEEALELLE 69


                  ....*...
gi 578798982  161 AAVDFYEE 168
Cdd:pfam13424  70 RALALAEK 77
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 146-293 1.59e-06

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 48.42  E-value: 1.59e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982 146 QDVGEFPEEVRDALQAAVDFYEENLSLVTALGDRAAQGRAFGNLGNTHYLLGNFRDAVIAHEQRLLIAKEFGDkaaerrA 225
Cdd:COG5010   17 LTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPE------L 90

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 578798982 226 YSNLGNAYIFLGEFETASEYYKKtlllARQLKDRAVEAQscYSLGNTYTLLQDYEKAIDYHLKHLAIA 293
Cdd:COG5010   91 YYNLALLYSRSGDKDEAKEYYEK----ALALSPDNPNAY--SNLAALLLSLGQDDEAKAALQRALGTS 152
GoLoco smart00390
LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins
 575-597 1.68e-06

LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins


Pssm-ID: 214645  Cd Length: 23  Bit Score: 44.80  E-value: 1.68e-06
                           10        20
                   ....*....|....*....|...
gi 578798982   575 DEDFFDILVKCQGSRLDDQRCAP 597
Cdd:smart00390   1 DEDLFDLLLRMQSSRMDDQRCEL 23
TPR_12 pfam13424
Tetratricopeptide repeat;
42-115 1.84e-06

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 45.84  E-value: 1.84e-06
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 578798982   42 LSAIYSQLGNAYFYLHDYAKALEYHHHDLTLARTI--GDQLGEAKASGNLGNTLKVLGNFDEAIVCCQRHLDISRE 115
Cdd:pfam13424   2 VATALNNLAAVLRRLGRYDEALELLEKALEIARRLlgPDHPLTATTLLNLGRLYLELGRYEEALELLERALALAEK 77
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 7-138 2.61e-06

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 47.49  E-value: 2.61e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982   7 ELALEGERLCKSGDCRAGVSFFEAAVQVGTEDLktlsAIYSQLGNAYFYLHDYAKALEYHHHDLTLARtigdqlGEAKAS 86
Cdd:COG4783    6 ALYALAQALLLAGDYDEAEALLEKALELDPDNP----EAFALLGEILLQLGDLDEAIVLLHEALELDP------DEPEAR 75

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 578798982  87 GNLGNTLKVLGNFDEAIVCCQRHLDISRElndkvgEARALYNLGNVYHAKGK 138
Cdd:COG4783   76 LNLGLALLKAGDYDEALALLEKALKLDPE------HPEAYLRLARAYRALGR 121
GoLoco pfam02188
GoLoco motif;
610-631 3.72e-06

GoLoco motif;


Pssm-ID: 460481  Cd Length: 22  Bit Score: 43.56  E-value: 3.72e-06
                          10        20
                  ....*....|....*....|..
gi 578798982  610 EDFFSLILRSQGKRMDEQRVLL 631
Cdd:pfam02188   1 EDFFDLLARVQSSRLDDQRCSL 22
GoLoco pfam02188
GoLoco motif;
576-595 3.86e-06

GoLoco motif;


Pssm-ID: 460481  Cd Length: 22  Bit Score: 43.56  E-value: 3.86e-06
                          10        20
                  ....*....|....*....|
gi 578798982  576 EDFFDILVKCQGSRLDDQRC 595
Cdd:pfam02188   1 EDFFDLLARVQSSRLDDQRC 20
GoLoco smart00390
LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins
 609-631 6.42e-06

LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins


Pssm-ID: 214645  Cd Length: 23  Bit Score: 42.87  E-value: 6.42e-06
                           10        20
                   ....*....|....*....|...
gi 578798982   609 DEDFFSLILRSQGKRMDEQRVLL 631
Cdd:smart00390   1 DEDLFDLLLRMQSSRMDDQRCEL 23
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
232-335 1.04e-05

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 44.39  E-value: 1.04e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982 232 AYIFLGEFETASEYYKKTLLLARQlkdravEAQSCYSLGNTYTLLQDYEKAIDYHLkhlaiAQELNDRIGEgrACWSLGN 311
Cdd:COG3063    1 LYLKLGDLEEAEEYYEKALELDPD------NADALNNLGLLLLEQGRYDEAIALEK-----ALKLDPNNAE--ALLNLAE 67

                         90       100
                 ....*....|....*....|....
gi 578798982 312 AYTALGNHDQAMHFAEKHLEISRE 335
Cdd:COG3063   68 LLLELGDYDEALAYLERALELDPS 91
FxSxx_TPR NF040586
FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about ...
 69-388 1.14e-05

FxSxx-COOH system tetratricopeptide repeat protein; Members of this family are typically about 850 amino acids long, or 1300 long because of an additional N-terminal domain. Proteins have a P-loop motif, GxGGxGKT, near the N-terminus of the region covered by this HMM, and a region over 400 residues long of tetratricopeptide repeat sequence. The family is found regularly next to other components of FxSxx-COOH systems, which feature an FxsB family radical SAM protein and a protein modified by it, FxsA. Members of this FxsA family typically have an FxSxx motif as the final five amino acids.


Pssm-ID: 468560 [Multi-domain]  Cd Length: 836  Bit Score: 48.76  E-value: 1.14e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982  69 DLTLARTIGDQLGEA-------------KASGNLGNTLKVLGNFDEAivccqrhldisRELNDKV-GEARALYNLGNVYH 134
Cdd:NF040586 407 DYESARDLAERALERwrerlgpddrqtlRLRFHLANALRSLGRYEEA-----------RELDEDTlERQRRVLGLGEDHP 475

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982 135 ----AKGkSFGcpgpQD---VGEFPE---EVRDALQAAVDFYEENlslvtalgDRAAQgRAFGNLGNTHYLLGNFRDAVI 204
Cdd:NF040586 476 htlmTAG-GLG----ADlraLGRFREaleLDEETLERHRRVFGED--------HPRTL-RAANNLAVSLRLLGDYREALE 541

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982 205 AHEQRLLIAKE-FG-DKAAERRAYSNLGNAYIFLGEF-------ETASEYYKKTLLLA------RQLKDRAVeaqSCYSL 269
Cdd:NF040586 542 LDREVLRRRRRvLGpDHPRTLLSANNLARDLRELGRYaealdllEEALERYREVLGGPdhpdtlRAAKSLAV---ALRRA 618

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982 270 GntytllqDYEKAidyhlkhLAIAQE----LNDRIGEG----RAC-WSLGNAYTALGNHDQAMHFAEKHLEISREVGdks 340
Cdd:NF040586 619 G-------RLEEA-------LELAEDtyerYRRRFGPDhpdtLAAaLSLANDLRALGDADEARELAREVLDRYRRVL--- 681

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....
gi 578798982 341 GE-----LTARLNLSDLQMVLGLSYstnnsimsENTEID-SSLNGVRPKLGRRH 388
Cdd:NF040586 682 GEdhpftLACRNNLAVLLRALGDPE--------EARELAeAALEGLRERLGPDH 727
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 224-333 1.23e-05

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 45.38  E-value: 1.23e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982 224 RAYSNLGNAYIFLGEFETASEYYKKtlllARQLKDRAVEAQscYSLGNTYTLLQDYEKAIdyhlKHLAIAQELNDRigEG 303
Cdd:COG4235   18 EGWLLLGRAYLRLGRYDEALAAYEK----ALRLDPDNADAL--LDLAEALLAAGDTEEAE----ELLERALALDPD--NP 85

                         90       100       110
                 ....*....|....*....|....*....|
gi 578798982 304 RACWSLGNAYTALGNHDQAMHFAEKHLEIS 333
Cdd:COG4235   86 EALYLLGLAAFQQGDYAEAIAAWQKLLALL 115
GoLoco pfam02188
GoLoco motif;
526-547 1.39e-05

GoLoco motif;


Pssm-ID: 460481  Cd Length: 22  Bit Score: 42.02  E-value: 1.39e-05
                          10        20
                  ....*....|....*....|..
gi 578798982  526 DEFLDLLASSQSRRLDDQRASF 547
Cdd:pfam02188   1 EDFFDLLARVQSSRLDDQRCSL 22
TPR_7 pfam13176
Tetratricopeptide repeat;
265-299 1.83e-05

Tetratricopeptide repeat;


Pssm-ID: 433012 [Multi-domain]  Cd Length: 36  Bit Score: 41.76  E-value: 1.83e-05
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 578798982  265 SCYSLGNTYTLLQDYEKAIDYHLKHLAIAQELNDR 299
Cdd:pfam13176   1 ALLNLGRIYRKLGDYDEAISLYEQALALAKDPYDR 35
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 229-333 2.83e-05

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 46.26  E-value: 2.83e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982 229 LGNAYIFLGEFETASEYYKKTLllarQLKDRAVEAQscYSLGNTYTLLQDYEKAIDYHLKHLAIAQElndrigEGRACWS 308
Cdd:COG2956   14 KGLNYLLNGQPDKAIDLLEEAL----ELDPETVEAH--LALGNLYRRRGEYDRAIRIHQKLLERDPD------RAEALLE 81

                         90       100
                 ....*....|....*....|....*
gi 578798982 309 LGNAYTALGNHDQAMHFAEKHLEIS 333
Cdd:COG2956   82 LAQDYLKAGLLDRAEELLEKLLELD 106
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
154-333 3.39e-05

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 45.68  E-value: 3.39e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982 154 EVRDALQAAVDFYEENLSLVTALGDRAAQGRAFGNLGNTHYLLGNFRDAVIAHEQRLLIAKEFGDKAaerRAYSNLGNAY 233
Cdd:COG4785    7 ALLLALALAAAAASKAAILLAALLFAAVLALAIALADLALALAAAALAAAALAAERIDRALALPDLA---QLYYERGVAY 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982 234 IFLGEFETASEYYKKTLllarQLKDRAVEAQscYSLGNTYTLLQDYEKAIDYhlkhLAIAQELNDRIGEgrACWSLGNAY 313
Cdd:COG4785   84 DSLGDYDLAIADFDQAL----ELDPDLAEAY--NNRGLAYLLLGDYDAALED----FDRALELDPDYAY--AYLNRGIAL 151

                        170       180
                 ....*....|....*....|
gi 578798982 314 TALGNHDQAMHFAEKHLEIS 333
Cdd:COG4785  152 YYLGRYELAIADLEKALELD 171
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
122-305 4.94e-05

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 45.29  E-value: 4.94e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982 122 EARALYNLGNVYHAKGKsfgcpgpqdvgefpeevrdaLQAAVDFYEenlslvTALGDRAAQGRAFGNLGNTHYLLGNFRD 201
Cdd:COG4785   72 LAQLYYERGVAYDSLGD--------------------YDLAIADFD------QALELDPDLAEAYNNRGLAYLLLGDYDA 125

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982 202 AVIAheqrlliakeFgDKAAERR-----AYSNLGNAYIFLGEFETASEYYKKTLLLARQLKDRAVEAQSCYslgntytLL 276
Cdd:COG4785  126 ALED----------F-DRALELDpdyayAYLNRGIALYYLGRYELAIADLEKALELDPNDPERALWLYLAE-------RK 187

                        170       180
                 ....*....|....*....|....*....
gi 578798982 277 QDYEKAIDYHLKHLAIAQELNDRIGEGRA 305
Cdd:COG4785  188 LDPEKALALLLEDWATAYLLQGDTEEARE 216
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 220-357 5.63e-05

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 43.64  E-value: 5.63e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982 220 AAERRAYSNLGNAYIFLGEFETASEYYKKtlllARQLKDRAVEAQscYSLGNTYTLLQDYEKAIDYHLKHLAIAQElndr 299
Cdd:COG4783    1 AACAEALYALAQALLLAGDYDEAEALLEK----ALELDPDNPEAF--ALLGEILLQLGDLDEAIVLLHEALELDPD---- 70

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 578798982 300 igEGRACWSLGNAYTALGNHDQAMHFAEKHLEISREVGDksgeltARLNLSDLQMVLG 357
Cdd:COG4783   71 --EPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPE------AYLRLARAYRALG 120
TPR_12 pfam13424
Tetratricopeptide repeat;
123-215 5.90e-05

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 41.60  E-value: 5.90e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982  123 ARALYNLGNVYHAKGKsfgcpgpqdvgefpeevrdaLQAAVDFYEENLSLVTAL--GDRAAQGRAFGNLGNTHYLLGNFR 200
Cdd:pfam13424   3 ATALNNLAAVLRRLGR--------------------YDEALELLEKALEIARRLlgPDHPLTATTLLNLGRLYLELGRYE 62

                          90
                  ....*....|....*
gi 578798982  201 DAVIAHEQRLLIAKE 215
Cdd:pfam13424  63 EALELLERALALAEK 77
GoLoco smart00390
LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins
 525-547 5.99e-05

LGN motif, putative GEFs specific for G-alpha GTPases; GEF specific for Galpha_i proteins


Pssm-ID: 214645  Cd Length: 23  Bit Score: 40.18  E-value: 5.99e-05
                           10        20
                   ....*....|....*....|...
gi 578798982   525 TDEFLDLLASSQSRRLDDQRASF 547
Cdd:smart00390   1 DEDLFDLLLRMQSSRMDDQRCEL 23
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 175-333 8.51e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 43.41  E-value: 8.51e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982 175 ALGDRAAQGRAFGNLGNTHYLLGNFRDAVIAHEQRLLIAKEFGDKAAERRAYSNLGNAYIFLGEFETASEYYKKtlllAR 254
Cdd:COG5010    6 GFDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQ----AL 81

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 578798982 255 QLKDRAVEAQscYSLGNTYTLLQDYEKAIdyhlKHLAIAQELNDriGEGRACWSLGNAYTALGNHDQAMHFAEKHLEIS 333
Cdd:COG5010   82 QLDPNNPELY--YNLALLYSRSGDKDEAK----EYYEKALALSP--DNPNAYSNLAALLLSLGQDDEAKAALQRALGTS 152
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
153-299 8.55e-05

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 44.52  E-value: 8.55e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982 153 EEVRDALQAAVDFYEENLSLVTALGDRAaqgRAFGNLGNTHYLLGNFRDAVIAHEQRLliaKEFGDKAaerRAYSNLGNA 232
Cdd:COG4785   46 LALAAAALAAAALAAERIDRALALPDLA---QLYYERGVAYDSLGDYDLAIADFDQAL---ELDPDLA---EAYNNRGLA 116

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 578798982 233 YIFLGEFETASEYYKKTLllarQLKDRAVEAQscYSLGNTYTLLQDYEKAIDYHLKHLAIAQELNDR 299
Cdd:COG4785  117 YLLLGDYDAALEDFDRAL----ELDPDYAYAY--LNRGIALYYLGRYELAIADLEKALELDPNDPER 177
COG3899 COG3899
Predicted ATPase [General function prediction only];
6-347 1.93e-04

Predicted ATPase [General function prediction only];


Pssm-ID: 443106 [Multi-domain]  Cd Length: 1244  Bit Score: 44.85  E-value: 1.93e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982    6 LELALE-GERLCKSGDCRAGVSFFEAAVQVGT-------EDLKTLSAIYSQLGNAYFYLHDYAKALEYHHHDLTLARTIG 77
Cdd:COG3899   745 LALLLElAEALYLAGRFEEAEALLERALAARAlaalaalRHGNPPASARAYANLGLLLLGDYEEAYEFGELALALAERLG 824

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982   78 DQLGEAKASGNLGNTLKVLGNFDEAIVCCQRHLDISRELNDKVGEARALYnlgnvyhakgkSFGCPGPQDVGEFPEEVRD 157
Cdd:COG3899   825 DRRLEARALFNLGFILHWLGPLREALELLREALEAGLETGDAALALLALA-----------AAAAAAAAAAALAAAAAAA 893

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982  158 ALQAAVDFYEENLSLVTALGDRAAQGRAFGNLGNTHYLLGNFRDAVIAHEQRLLIAKEfgdkAAERRAYSNLGNAYIFLG 237
Cdd:COG3899   894 ARLLAAAAAALAAAAAAAALAAAELARLAAAAAAAAALALAAAAAAAAAAALAAAAAA----AALAAALALAAAAAAAAA 969

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982  238 EFETASEYYKKTLLLARQLKDRAVEAQSCYSLGNTYTLLQDYEKAIDYHLKHLAIAQELNDRIGEGRACWSLGNAYTALG 317
Cdd:COG3899   970 AALAAAAAAAAAAAAAAAAAALEAAAAALLALLAAAAAAAAAAAALAAALLAAALAALAAAAAAAALLAAAAALALLAAL 1049

                         330       340       350
                  ....*....|....*....|....*....|
gi 578798982  318 NHDQAMHFAEKHLEISREVGDKSGELTARL 347
Cdd:COG3899  1050 AAAAAAAAAAAALAAAAALLAAAAAAAAAA 1079
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 193-285 2.68e-04

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 40.75  E-value: 2.68e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982 193 HYLLGNFRDAVIAHEQrllIAKEFGDKAAERRAYSNLGNAYIFLGEFETASEYYKKtllLARQLKDRAVEAQSCYSLGNT 272
Cdd:COG1729    3 LLKAGDYDEAIAAFKA---FLKRYPNSPLAPDALYWLGEAYYALGDYDEAAEAFEK---LLKRYPDSPKAPDALLKLGLS 76

                         90
                 ....*....|...
gi 578798982 273 YTLLQDYEKAIDY 285
Cdd:COG1729   77 YLELGDYDKARAT 89
TPR_1 pfam00515
Tetratricopeptide repeat;
224-255 3.06e-04

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 38.56  E-value: 3.06e-04
                          10        20        30
                  ....*....|....*....|....*....|..
gi 578798982  224 RAYSNLGNAYIFLGEFETASEYYKKTLLLARQ 255
Cdd:pfam00515   2 KALYNLGNAYFKLGKYDEALEYYEKALELNPN 33
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 160-248 4.11e-04

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 40.36  E-value: 4.11e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982 160 QAAVDFYEEnlsLVTALGDRAAQGRAFGNLGNTHYLLGNFRDAVIAHEQrllIAKEFGDKAAERRAYSNLGNAYIFLGEF 239
Cdd:COG1729   10 DEAIAAFKA---FLKRYPNSPLAPDALYWLGEAYYALGDYDEAAEAFEK---LLKRYPDSPKAPDALLKLGLSYLELGDY 83


                 ....*....
gi 578798982 240 ETASEYYKK 248
Cdd:COG1729   84 DKARATLEE 92
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 38-214 4.65e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 41.10  E-value: 4.65e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982  38 DLKTLSAIYSQLGNAYFYLHDYAKALEYHHHDLTLARTIGDQLGEAKASGNLGNTLKVLGNFDEAIVCCQRHLDISREln 117
Cdd:COG5010    9 RLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPN-- 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982 118 dkvgEARALYNLGNVYHAKGKsfgcpgpqdvgefpeevrdaLQAAVDFYEEnlslvtALGDRAAQGRAFGNLGNTHYLLG 197
Cdd:COG5010   87 ----NPELYYNLALLYSRSGD--------------------KDEAKEYYEK------ALALSPDNPNAYSNLAALLLSLG 136

                        170
                 ....*....|....*..
gi 578798982 198 NFRDAVIAHEQRLLIAK 214
Cdd:COG5010  137 QDDEAKAALQRALGTSP 153
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 232-322 5.03e-04

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 39.97  E-value: 5.03e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982 232 AYIFLGEFETASEYYKKtllLARQLKDRAVEAQSCYSLGNTYTLLQDYEKAIDYHLKhlaIAQELNDRIGEGRACWSLGN 311
Cdd:COG1729    2 ALLKAGDYDEAIAAFKA---FLKRYPNSPLAPDALYWLGEAYYALGDYDEAAEAFEK---LLKRYPDSPKAPDALLKLGL 75

                         90
                 ....*....|.
gi 578798982 312 AYTALGNHDQA 322
Cdd:COG1729   76 SYLELGDYDKA 86
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 263-295 5.15e-04

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 37.81  E-value: 5.15e-04
                           10        20        30
                   ....*....|....*....|....*....|...
gi 578798982   263 AQSCYSLGNTYTLLQDYEKAIDYHLKHLAIAQE 295
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPN 33
TPR_1 pfam00515
Tetratricopeptide repeat;
83-112 6.51e-04

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 37.40  E-value: 6.51e-04
                          10        20        30
                  ....*....|....*....|....*....|
gi 578798982   83 AKASGNLGNTLKVLGNFDEAIVCCQRHLDI 112
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALEL 30
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 224-255 6.53e-04

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 37.43  E-value: 6.53e-04
                           10        20        30
                   ....*....|....*....|....*....|..
gi 578798982   224 RAYSNLGNAYIFLGEFETASEYYKKTLLLARQ 255
Cdd:smart00028   2 EALYNLGNAYLKLGDYDEALEYYEKALELDPN 33
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 83-115 1.11e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 36.66  E-value: 1.11e-03
                           10        20        30
                   ....*....|....*....|....*....|...
gi 578798982    83 AKASGNLGNTLKVLGNFDEAIVCCQRHLDISRE 115
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPN 33
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
42-250 1.29e-03

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 40.67  E-value: 1.29e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982  42 LSAIYSQLGNAYFYLHDYAKALEyhhhDLTLArtIGDQLGEAKASGNLGNTLKVLGNFDEAIVCCQRHLdisrELNDKvg 121
Cdd:COG4785   72 LAQLYYERGVAYDSLGDYDLAIA----DFDQA--LELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRAL----ELDPD-- 139

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982 122 EARALYNLGNVYHAKGKsfgcpgpqdvgefPEEVRDALQAAVDFYEENlslvtalgdraaqgrafgnlgnthyllgnfrd 201
Cdd:COG4785  140 YAYAYLNRGIALYYLGR-------------YELAIADLEKALELDPND-------------------------------- 174

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 578798982 202 aVIAHEQRLLIAKEFGDKAAERRAYSNLGNAYIFLGEFETASEYYKKTL 250
Cdd:COG4785  175 -PERALWLYLAERKLDPEKALALLLEDWATAYLLQGDTEEARELFKLAL 222
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 123-264 1.49e-03

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 39.22  E-value: 1.49e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982 123 ARALYNLGNVYHAKGKsfgcpgpqdvgefPEEVRDALQAAVDFYEENLSlvtalgdraaqgrAFGNLGNTHYLLGNFRDA 202
Cdd:COG4235   17 AEGWLLLGRAYLRLGR-------------YDEALAAYEKALRLDPDNAD-------------ALLDLAEALLAAGDTEEA 70

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 578798982 203 VIAHEQRLLIAKEFGdkaaerRAYSNLGNAYIFLGEFETASEYYKKTL-LLARQLKDRAVEAQ 264
Cdd:COG4235   71 EELLERALALDPDNP------EALYLLGLAAFQQGDYAEAIAAWQKLLaLLPADAPARLLEAS 127
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 88-211 1.64e-03

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 39.22  E-value: 1.64e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982  88 NLGNTLKVLGNFDEAIVCCQRHLDISRElndkvgEARALYNLGNVYHAKGKsfgcpgpqdvgefPEEVRDALQAAVDFYE 167
Cdd:COG4235   22 LLGRAYLRLGRYDEALAAYEKALRLDPD------NADALLDLAEALLAAGD-------------TEEAEELLERALALDP 82

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 578798982 168 ENLslvtalgdraaqgRAFGNLGNTHYLLGNFRDAvIAHEQRLL 211
Cdd:COG4235   83 DNP-------------EALYLLGLAAFQQGDYAEA-IAAWQKLL 112
TPR_7 pfam13176
Tetratricopeptide repeat;
225-260 2.14e-03

Tetratricopeptide repeat;


Pssm-ID: 433012 [Multi-domain]  Cd Length: 36  Bit Score: 35.98  E-value: 2.14e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 578798982  225 AYSNLGNAYIFLGEFETASEYYKKTLLLARQLKDRA 260
Cdd:pfam13176   1 ALLNLGRIYRKLGDYDEAISLYEQALALAKDPYDRE 36
TPR_7 pfam13176
Tetratricopeptide repeat;
305-340 2.20e-03

Tetratricopeptide repeat;


Pssm-ID: 433012 [Multi-domain]  Cd Length: 36  Bit Score: 35.98  E-value: 2.20e-03
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 578798982  305 ACWSLGNAYTALGNHDQAMHFAEKHLEISREVGDKS 340
Cdd:pfam13176   1 ALLNLGRIYRKLGDYDEAISLYEQALALAKDPYDRE 36
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
193-296 2.33e-03

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 37.84  E-value: 2.33e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982 193 HYLLGNFRDAVIAHEQRLLIAKEFGDkaaerrAYSNLGNAYIFLGEFETASEYYKktlllARQLKDRAVEAQscYSLGNT 272
Cdd:COG3063    2 YLKLGDLEEAEEYYEKALELDPDNAD------ALNNLGLLLLEQGRYDEAIALEK-----ALKLDPNNAEAL--LNLAEL 68

                         90       100
                 ....*....|....*....|....
gi 578798982 273 YTLLQDYEKAIDYHLKHLAIAQEL 296
Cdd:COG3063   69 LLELGDYDEALAYLERALELDPSA 92
TPR_11 pfam13414
TPR repeat;
90-137 3.11e-03

TPR repeat;


Pssm-ID: 315977 [Multi-domain]  Cd Length: 42  Bit Score: 35.91  E-value: 3.11e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*...
gi 578798982   90 GNTLKVLGNFDEAIVCCQRHLDISRELndkvgeARALYNLGNVYHAKG 137
Cdd:pfam13414   1 GDAYYEQGKYEEAIEAYKKALKLDPDN------PEAYYNLGLAYYKLG 42
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
52-138 3.15e-03

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 37.46  E-value: 3.15e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982  52 AYFYLHDYAKALEYHHHDLTLARtigdqlGEAKASGNLGNTLKVLGNFDEAIVcCQRHLDISRElndkvgEARALYNLGN 131
Cdd:COG3063    1 LYLKLGDLEEAEEYYEKALELDP------DNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPN------NAEALLNLAE 67


                 ....*..
gi 578798982 132 VYHAKGK 138
Cdd:COG3063   68 LLLELGD 74
TPR_1 pfam00515
Tetratricopeptide repeat;
263-295 3.94e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 35.47  E-value: 3.94e-03
                          10        20        30
                  ....*....|....*....|....*....|...
gi 578798982  263 AQSCYSLGNTYTLLQDYEKAIDYHLKHLAIAQE 295
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPN 33
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
159-256 5.34e-03

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 36.69  E-value: 5.34e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982 159 LQAAVDFYEENLSLvtalgdRAAQGRAFGNLGNTHYLLGNFRDAvIAHEQRLLIAKEFGDkaaerrAYSNLGNAYIFLGE 238
Cdd:COG3063    8 LEEAEEYYEKALEL------DPDNADALNNLGLLLLEQGRYDEA-IALEKALKLDPNNAE------ALLNLAELLLELGD 74

                         90
                 ....*....|....*...
gi 578798982 239 FETASEYYKKTLLLARQL 256
Cdd:COG3063   75 YDEALAYLERALELDPSA 92
TPR COG0790
TPR repeat [General function prediction only];
51-293 5.40e-03

TPR repeat [General function prediction only];


Pssm-ID: 440553 [Multi-domain]  Cd Length: 241  Bit Score: 39.14  E-value: 5.40e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982  51 NAYFYLHDYAKALEYHHHDLTLARTIGDQLGEAKASGNLG----NTLKVLGNFDEAIVCCQRhldiSRELndkvGEARAL 126
Cdd:COG0790   31 AAAAAAAAAALAAAAGAAAAAAAAAAAAAAGGAEAQYNLGlmyaEGRGVPKDYEKALEWFEK----AAEQ----GDAEAQ 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982 127 YNLGNVYHakgksFGCPGPQDvgefpeevrdaLQAAVDFYEEnlslVTALGDRAAQgrafgnlgnthYLLGNFRDAVIAH 206
Cdd:COG0790  103 YNLGLMYE-----EGLGVPQD-----------YAKALEWYEK----AAEQGDADAQ-----------YNLGLLYLNGEGV 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578798982 207 EQRLLIAKEFGDKAAER---RAYSNLGNAYiFLGE-----FETASEYYKKtlllARQLKDraveAQSCYSLGNTYT---- 274
Cdd:COG0790  152 PKDPAKAAEWYRKAAEQgdaDAQYNLGVLY-ENGRgvpkdPAKALEWYRK----AAEQGD----ADAQYNLGRLYLngeg 222

                        250
                 ....*....|....*....
gi 578798982 275 LLQDYEKAIDYHLKHLAIA 293
Cdd:COG0790  223 VEKDLEKALRWLRKAAEQA 241
TPR_8 pfam13181
Tetratricopeptide repeat;
224-248 6.37e-03

Tetratricopeptide repeat;


Pssm-ID: 404131 [Multi-domain]  Cd Length: 33  Bit Score: 34.68  E-value: 6.37e-03
                          10        20
                  ....*....|....*....|....*
gi 578798982  224 RAYSNLGNAYIFLGEFETASEYYKK 248
Cdd:pfam13181   2 EAYYNLGLIYLKLGDYEEAKEYYEK 26
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 45-75 6.86e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 34.73  E-value: 6.86e-03
                           10        20        30
                   ....*....|....*....|....*....|.
gi 578798982    45 IYSQLGNAYFYLHDYAKALEYHHHDLTLART 75
Cdd:smart00028   3 ALYNLGNAYLKLGDYDEALEYYEKALELDPN 33
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 304-335 9.77e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 34.34  E-value: 9.77e-03
                           10        20        30
                   ....*....|....*....|....*....|..
gi 578798982   304 RACWSLGNAYTALGNHDQAMHFAEKHLEISRE 335
Cdd:smart00028   2 EALYNLGNAYLKLGDYDEALEYYEKALELDPN 33
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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