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A-kinase anchor protein SPHKAP isoform X3 [Homo sapiens]
List of domain hits
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Name | Accession | Description | Interval | E-value | |||
AKAP_110 super family | cl14906 | A-kinase anchor protein 110 kDa (AKAP 110); This family consists of several mammalian protein ... |
1593-1693 | 9.44e-11 | |||
A-kinase anchor protein 110 kDa (AKAP 110); This family consists of several mammalian protein kinase A anchoring protein 3 (PRKA3) or A-kinase anchor protein 110 kDa (AKAP 110) sequences. Agents that increase intracellular cAMP are potent stimulators of sperm motility. Anchoring inhibitor peptides, designed to disrupt the interaction of the cAMP-dependent protein kinase A (PKA) with A kinase-anchoring proteins (AKAPs), are potent inhibitors of sperm motility. PKA anchoring is a key biochemical mechanism controlling motility. AKAP110 shares compartments with both RI and RII isoforms of PKA and may function as a regulator of both motility- and head-associated functions such as capacitation and the acrosome reaction. The actual alignment was detected with superfamily member pfam05716: Pssm-ID: 449376 Cd Length: 692 Bit Score: 66.87 E-value: 9.44e-11
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Name | Accession | Description | Interval | E-value | |||
AKAP_110 | pfam05716 | A-kinase anchor protein 110 kDa (AKAP 110); This family consists of several mammalian protein ... |
1593-1693 | 9.44e-11 | |||
A-kinase anchor protein 110 kDa (AKAP 110); This family consists of several mammalian protein kinase A anchoring protein 3 (PRKA3) or A-kinase anchor protein 110 kDa (AKAP 110) sequences. Agents that increase intracellular cAMP are potent stimulators of sperm motility. Anchoring inhibitor peptides, designed to disrupt the interaction of the cAMP-dependent protein kinase A (PKA) with A kinase-anchoring proteins (AKAPs), are potent inhibitors of sperm motility. PKA anchoring is a key biochemical mechanism controlling motility. AKAP110 shares compartments with both RI and RII isoforms of PKA and may function as a regulator of both motility- and head-associated functions such as capacitation and the acrosome reaction. Pssm-ID: 428603 Cd Length: 692 Bit Score: 66.87 E-value: 9.44e-11
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AKAP_110 | smart00807 | A-kinase anchor protein 110 kDa; This family consists of several mammalian protein kinase A ... |
1593-1693 | 2.79e-09 | |||
A-kinase anchor protein 110 kDa; This family consists of several mammalian protein kinase A anchoring protein 3 (PRKA3) or A-kinase anchor protein 110 kDa (AKAP 110) sequences. Agents that increase intracellular cAMP are potent stimulators of sperm motility. Anchoring inhibitor peptides, designed to disrupt the interaction of the cAMP-dependent protein kinase A (PKA) with A kinase-anchoring proteins (AKAPs), are potent inhibitors of sperm motility. PKA anchoring is a key biochemical mechanism controlling motility. AKAP110 shares compartments with both RI and RII isoforms of PKA and may function as a regulator of both motility- and head-associated functions such as capacitation and the acrosome reaction. Pssm-ID: 214827 Cd Length: 851 Bit Score: 61.96 E-value: 2.79e-09
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Name | Accession | Description | Interval | E-value | |||
AKAP_110 | pfam05716 | A-kinase anchor protein 110 kDa (AKAP 110); This family consists of several mammalian protein ... |
1593-1693 | 9.44e-11 | |||
A-kinase anchor protein 110 kDa (AKAP 110); This family consists of several mammalian protein kinase A anchoring protein 3 (PRKA3) or A-kinase anchor protein 110 kDa (AKAP 110) sequences. Agents that increase intracellular cAMP are potent stimulators of sperm motility. Anchoring inhibitor peptides, designed to disrupt the interaction of the cAMP-dependent protein kinase A (PKA) with A kinase-anchoring proteins (AKAPs), are potent inhibitors of sperm motility. PKA anchoring is a key biochemical mechanism controlling motility. AKAP110 shares compartments with both RI and RII isoforms of PKA and may function as a regulator of both motility- and head-associated functions such as capacitation and the acrosome reaction. Pssm-ID: 428603 Cd Length: 692 Bit Score: 66.87 E-value: 9.44e-11
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AKAP_110 | smart00807 | A-kinase anchor protein 110 kDa; This family consists of several mammalian protein kinase A ... |
1593-1693 | 2.79e-09 | |||
A-kinase anchor protein 110 kDa; This family consists of several mammalian protein kinase A anchoring protein 3 (PRKA3) or A-kinase anchor protein 110 kDa (AKAP 110) sequences. Agents that increase intracellular cAMP are potent stimulators of sperm motility. Anchoring inhibitor peptides, designed to disrupt the interaction of the cAMP-dependent protein kinase A (PKA) with A kinase-anchoring proteins (AKAPs), are potent inhibitors of sperm motility. PKA anchoring is a key biochemical mechanism controlling motility. AKAP110 shares compartments with both RI and RII isoforms of PKA and may function as a regulator of both motility- and head-associated functions such as capacitation and the acrosome reaction. Pssm-ID: 214827 Cd Length: 851 Bit Score: 61.96 E-value: 2.79e-09
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