|
Name |
Accession |
Description |
Interval |
E-value |
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
817-1215 |
1.91e-14 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 79.21 E-value: 1.91e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 817 PRLPQAGARDPPVHLLQASSSAQSTPGHLFPNVPAQEASKSASHKGSRRLASSRVERTLPQASLLASTGPRPKPKTVSEL 896
Cdd:PHA03247 2616 PLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSL 2695
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 897 LQ------EKRLQEARAREATRGpvvLPSQLLVSSSVILQPPLPHTPHGRPAPGPTVLNVPLSGPGAPAAakpgTSGSwq 970
Cdd:PHA03247 2696 TSladpppPPPTPEPAPHALVSA---TPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPT----TAGP-- 2766
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 971 EAGTSAKDKRLSTMQALPLAPVFSEAEgTAPAASQAPALGPGQISVSCPESGLGQSQAPAAsrkqGLPEAPPFLPAAPSP 1050
Cdd:PHA03247 2767 PAPAPPAAPAAGPPRRLTRPAVASLSE-SRESLPSPWDPADPPAAVLAPAAALPPAASPAG----PLPPPTSAQPTAPPP 2841
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 1051 TPLPVQPlSLTHIGGphVATSVPlpVTWVLTAQGLLPVPV----PAVVSLPRPAGTPGPAGLLATLLPPLTEtRAAQGPR 1126
Cdd:PHA03247 2842 PPGPPPP-SLPLGGS--VAPGGD--VRRRPPSRSPAAKPAaparPPVRRLARPAVSRSTESFALPPDQPERP-PQPQAPP 2915
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 1127 APALSSSWQPPANMNREPEPSCRTDTPAPPThALSQSPAEADGSVAFVPGEAQVAREIPEPRTSSHADPPEAEPPWSGRL 1206
Cdd:PHA03247 2916 PPQPQPQPPPPPQPQPPPPPPPRPQPPLAPT-TDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPASSTP 2994
|
....*....
gi 578817790 1207 PAFGGVIPA 1215
Cdd:PHA03247 2995 PLTGHSLSR 3003
|
|
| SANT |
smart00717 |
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; |
401-448 |
4.00e-14 |
|
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
Pssm-ID: 197842 [Multi-domain] Cd Length: 49 Bit Score: 67.63 E-value: 4.00e-14
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 578817790 401 KGYWAPEEDAKLLQAVAKYGEQDWFKIREEVPGRSDAQCRDRYLRRLH 448
Cdd:smart00717 1 KGEWTEEEDELLIELVKKYGKNNWEKIAKELPGRTAEQCRERWRNLLK 48
|
|
| SANT |
cd00167 |
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ... |
404-447 |
1.15e-13 |
|
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.
Pssm-ID: 238096 [Multi-domain] Cd Length: 45 Bit Score: 66.44 E-value: 1.15e-13
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 578817790 404 WAPEEDAKLLQAVAKYGEQDWFKIREEVPGRSDAQCRDRYLRRL 447
Cdd:cd00167 2 WTEEEDELLLEAVKKYGKNNWEKIAKELPGRTPKQCRERWRNLL 45
|
|
| Myb_DNA-binding |
pfam00249 |
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ... |
401-447 |
2.37e-12 |
|
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.
Pssm-ID: 459731 [Multi-domain] Cd Length: 46 Bit Score: 62.52 E-value: 2.37e-12
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 578817790 401 KGYWAPEEDAKLLQAVAKYGEqDWFKIREEVPGRSDAQCRDRYLRRL 447
Cdd:pfam00249 1 RGPWTPEEDELLLEAVEKLGN-RWKKIAKLLPGRTDNQCKNRWQNYL 46
|
|
| Myb_DNA-bind_6 |
pfam13921 |
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ... |
297-357 |
2.30e-08 |
|
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.
Pssm-ID: 372817 [Multi-domain] Cd Length: 60 Bit Score: 51.93 E-value: 2.30e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 578817790 297 WSREEEERLQAIAAAHGhLEWQKIAEELGtSRSAFQCLQKFQQHNKA-LKRKEWTEEEDRML 357
Cdd:pfam13921 1 WTEEEDEKLLKLVEKYG-NDWKQIAKELG-RRTPKQCFDRWRRKLNPkISRGPWSKEEDQRL 60
|
|
| PLN03091 |
PLN03091 |
hypothetical protein; Provisional |
399-502 |
2.69e-08 |
|
hypothetical protein; Provisional
Pssm-ID: 215570 [Multi-domain] Cd Length: 459 Bit Score: 58.06 E-value: 2.69e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 399 LKKGYWAPEEDAKLLQAVAKYGEQDWfkirEEVPGRSDAQ-----CRDRYLRRLHFSLKKGRWNLKEEEQLIELIEKYGv 473
Cdd:PLN03091 12 LRKGLWSPEEDEKLLRHITKYGHGCW----SSVPKQAGLQrcgksCRLRWINYLRPDLKRGTFSQQEENLIIELHAVLG- 86
|
90 100
....*....|....*....|....*....
gi 578817790 474 GHWAKIASELPHRSGSQCLSKWKIMMGKK 502
Cdd:PLN03091 87 NRWSQIAAQLPGRTDNEIKNLWNSCLKKK 115
|
|
| SANT |
smart00717 |
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; |
294-342 |
2.73e-08 |
|
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
Pssm-ID: 197842 [Multi-domain] Cd Length: 49 Bit Score: 51.46 E-value: 2.73e-08
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 578817790 294 KQEWSREEEERLQAIAAAHGHLEWQKIAEELGTsRSAFQCLQKFQQHNK 342
Cdd:smart00717 1 KGEWTEEEDELLIELVKKYGKNNWEKIAKELPG-RTAEQCRERWRNLLK 48
|
|
| SANT |
smart00717 |
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; |
346-397 |
1.44e-07 |
|
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
Pssm-ID: 197842 [Multi-domain] Cd Length: 49 Bit Score: 49.14 E-value: 1.44e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 578817790 346 RKEWTEEEDRMLTQLVQEMRVGShipYRRIVYYMEGRDSMQLIYRWTKSLDP 397
Cdd:smart00717 1 KGEWTEEEDELLIELVKKYGKNN---WEKIAKELPGRTAEQCRERWRNLLKP 49
|
|
| SANT_CDC5_II |
cd11659 |
SANT/myb-like DNA-binding domain of Cell Division Cycle 5-Like Protein repeat II; In humans, ... |
290-339 |
1.64e-07 |
|
SANT/myb-like DNA-binding domain of Cell Division Cycle 5-Like Protein repeat II; In humans, cell division cycle 5-like protein (CDC5) functions in pre-mRNA splicing in cell cycle control. The DNA-binding, myb-like domain of CDC5 is a member of the SANT/myb group. SANT is named after 'SWI3, ADA2, N-CoR and TFIIIB', several factors that share this domain. The SANT domain resembles the 3 alpha-helix bundle of DNA-binding Myb domains and is found in a diverse set of proteins.
Pssm-ID: 212557 [Multi-domain] Cd Length: 53 Bit Score: 49.23 E-value: 1.64e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 578817790 290 PSINKQEWSREEEERLQAIaAAHGHLEWQKIAEELGtsRSAFQCLQKFQQ 339
Cdd:cd11659 1 PSIKKTEWTREEDEKLLHL-AKLLPTQWRTIAPIVG--RTAQQCLERYNK 47
|
|
| REB1 |
COG5147 |
Myb superfamily proteins, including transcription factors and mRNA splicing factors ... |
256-357 |
2.99e-07 |
|
Myb superfamily proteins, including transcription factors and mRNA splicing factors [Transcription / RNA processing and modification / Cell division and chromosome partitioning];
Pssm-ID: 227476 [Multi-domain] Cd Length: 512 Bit Score: 54.79 E-value: 2.99e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 256 NRLDShDWEKISNINFE------GSRSAEEIRKFWQNSEHPSINKQEWSREEEERLQAIAAAHGHLeWQKIAEELGtSRS 329
Cdd:COG5147 29 EDLKA-LVKKLGPNNWSkvasllISSTGKQSSNRWNNHLNPQLKKKNWSEEEDEQLIDLDKELGTQ-WSTIADYKD-RRT 105
|
90 100
....*....|....*....|....*...
gi 578817790 330 AFQCLQKFQQHNKALKRKEWTEEEDRML 357
Cdd:COG5147 106 AQQCVERYVNTLEDLSSTHDSKLQRRNE 133
|
|
| DUF5585 |
pfam17823 |
Family of unknown function (DUF5585); This is a family of unknown function found in chordata. |
836-1230 |
4.44e-07 |
|
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
Pssm-ID: 465521 [Multi-domain] Cd Length: 506 Bit Score: 54.20 E-value: 4.44e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 836 SSAQSTPGHLFPNVPAQ-EASKSASHKGSRRLASSRVER----TLPQASLLASTGPrPKPKTVSELLQEKRLQEAR--AR 908
Cdd:pfam17823 11 FSLPLSESHAAPADPRHfVLNKMWNGAGKQNASGDAVPRadnkSSEQ*NFCAATAA-PAPVTLTKGTSAAHLNSTEvtAE 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 909 EATRG-----PVVLPSQLLVSSSVILQPPLPHTPHGRPAPGPTVLNVPLS-GPGAPAAAKPGTSGSwqeAGTSAKDKRLS 982
Cdd:pfam17823 90 HTPHGtdlsePATREGAADGAASRALAAAASSSPSSAAQSLPAAIAALPSeAFSAPRAAACRANAS---AAPRAAIAAAS 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 983 TMQALPLAPVFSEAEGTAPAASQAPALGPGQISVSCPESGLGQSQAPAASRKQGLPEAPPFLPAAPSPTPLPVQPLSLTH 1062
Cdd:pfam17823 167 APHAASPAPRTAASSTTAASSTTAASSAPTTAASSAPATLTPARGISTAATATGHPAAGTALAAVGNSSPAAGTVTAAVG 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 1063 IGGPHVATSVPLPVTWVLTAQGLLPVPVPAVVSLPRPAGTPGPAGLLATLLPPLTETraaQGPRAPAlsSSWQPPANMNR 1142
Cdd:pfam17823 247 TVTPAALATLAAAAGTVASAAGTINMGDPHARRLSPAKHMPSDTMARNPAAPMGAQA---QGPIIQV--STDQPVHNTAG 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 1143 EPEPSCRTDTPAPPTHALSQSPAEADGSVAFVPGEAQVAREIPEPRTSShadPPEAEPPWSGRLPAfggVIPATEPRGTP 1222
Cdd:pfam17823 322 EPTPSPSNTTLEPNTPKSVASTNLAVVTTTKAQAKEPSASPVPVLHTSM---IPEVEATSPTTQPS---PLLPTQGAAGP 395
|
....*...
gi 578817790 1223 GSPSGTQE 1230
Cdd:pfam17823 396 GILLAPEQ 403
|
|
| REB1 |
COG5147 |
Myb superfamily proteins, including transcription factors and mRNA splicing factors ... |
334-453 |
5.18e-07 |
|
Myb superfamily proteins, including transcription factors and mRNA splicing factors [Transcription / RNA processing and modification / Cell division and chromosome partitioning];
Pssm-ID: 227476 [Multi-domain] Cd Length: 512 Bit Score: 54.02 E-value: 5.18e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 334 LQKFQQHNKALKRKE--WTEEEDRMLTQLVQEM------RVGSHIPYRrivyyMEGRDSMqliyRWTKSLDPGLKKGYWA 405
Cdd:COG5147 6 NKELQIKLMQTKRKGgsWKRTEDEDLKALVKKLgpnnwsKVASLLISS-----TGKQSSN----RWNNHLNPQLKKKNWS 76
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 578817790 406 PEEDAKLLQAVAKYGEQdWFKIREEVPGRSDAQCRDRYLRRLHFSLKK 453
Cdd:COG5147 77 EEEDEQLIDLDKELGTQ-WSTIADYKDRRTAQQCVERYVNTLEDLSST 123
|
|
| Myb_DNA-bind_6 |
pfam13921 |
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ... |
349-412 |
3.31e-06 |
|
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.
Pssm-ID: 372817 [Multi-domain] Cd Length: 60 Bit Score: 45.76 E-value: 3.31e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 578817790 349 WTEEEDRMLTQLVQEMrvgsHIPYRRIVYYMEGRDSMQLIYRWTKSLDPGLKKGYWAPEEDAKL 412
Cdd:pfam13921 1 WTEEEDEKLLKLVEKY----GNDWKQIAKELGRRTPKQCFDRWRRKLNPKISRGPWSKEEDQRL 60
|
|
| SANT |
cd00167 |
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ... |
470-496 |
4.31e-06 |
|
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.
Pssm-ID: 238096 [Multi-domain] Cd Length: 45 Bit Score: 44.87 E-value: 4.31e-06
10 20
....*....|....*....|....*..
gi 578817790 470 KYGVGHWAKIASELPHRSGSQCLSKWK 496
Cdd:cd00167 16 KYGKNNWEKIAKELPGRTPKQCRERWR 42
|
|
| SANT |
smart00717 |
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; |
470-496 |
5.70e-06 |
|
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
Pssm-ID: 197842 [Multi-domain] Cd Length: 49 Bit Score: 44.52 E-value: 5.70e-06
10 20
....*....|....*....|....*..
gi 578817790 470 KYGVGHWAKIASELPHRSGSQCLSKWK 496
Cdd:smart00717 18 KYGKNNWEKIAKELPGRTAEQCRERWR 44
|
|
| REB1 |
COG5147 |
Myb superfamily proteins, including transcription factors and mRNA splicing factors ... |
399-495 |
4.68e-05 |
|
Myb superfamily proteins, including transcription factors and mRNA splicing factors [Transcription / RNA processing and modification / Cell division and chromosome partitioning];
Pssm-ID: 227476 [Multi-domain] Cd Length: 512 Bit Score: 47.86 E-value: 4.68e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 399 LKKGYWAPEEDAKLLQAVAKYGEQDWFKIREEVPGRSDAQCRDRYLRRLHFSLKKGRWNLKEEEQLIELIEKYGVgHWAK 478
Cdd:COG5147 18 RKGGSWKRTEDEDLKALVKKLGPNNWSKVASLLISSTGKQSSNRWNNHLNPQLKKKNWSEEEDEQLIDLDKELGT-QWST 96
|
90
....*....|....*..
gi 578817790 479 IASELPHRSGSQCLSKW 495
Cdd:COG5147 97 IADYKDRRTAQQCVERY 113
|
|
| Myb_DNA-bind_6 |
pfam13921 |
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ... |
262-305 |
1.36e-04 |
|
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.
Pssm-ID: 372817 [Multi-domain] Cd Length: 60 Bit Score: 41.14 E-value: 1.36e-04
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 578817790 262 DWEKISNInfEGSRSAEEIRKFWQNSEHPSINKQEWSREEEERL 305
Cdd:pfam13921 19 DWKQIAKE--LGRRTPKQCFDRWRRKLNPKISRGPWSKEEDQRL 60
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
193-359 |
1.91e-03 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 43.03 E-value: 1.91e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 193 RKSVVSDRLQRL---LQPKLLKLEYLHQKQSKVSSELERQALEKQGREAEKEIQdiNQLPEEALLGNRLD-SHDWEKISN 268
Cdd:TIGR00618 220 RKQVLEKELKHLreaLQQTQQSHAYLTQKREAQEEQLKKQQLLKQLRARIEELR--AQEAVLEETQERINrARKAAPLAA 297
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 269 InfegSRSAEEIRKFWQNSeHPSINKQEWSReEEERLQAIAAAHGHLEWQKIAEELGTSRSafQCLQKFQQHNKALKRKE 348
Cdd:TIGR00618 298 H----IKAVTQIEQQAQRI-HTELQSKMRSR-AKLLMKRAAHVKQQSSIEEQRRLLQTLHS--QEIHIRDAHEVATSIRE 369
|
170
....*....|....*
gi 578817790 349 ----WTEEEDRMLTQ 359
Cdd:TIGR00618 370 iscqQHTLTQHIHTL 384
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
817-1215 |
1.91e-14 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 79.21 E-value: 1.91e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 817 PRLPQAGARDPPVHLLQASSSAQSTPGHLFPNVPAQEASKSASHKGSRRLASSRVERTLPQASLLASTGPRPKPKTVSEL 896
Cdd:PHA03247 2616 PLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSL 2695
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 897 LQ------EKRLQEARAREATRGpvvLPSQLLVSSSVILQPPLPHTPHGRPAPGPTVLNVPLSGPGAPAAakpgTSGSwq 970
Cdd:PHA03247 2696 TSladpppPPPTPEPAPHALVSA---TPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPT----TAGP-- 2766
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 971 EAGTSAKDKRLSTMQALPLAPVFSEAEgTAPAASQAPALGPGQISVSCPESGLGQSQAPAAsrkqGLPEAPPFLPAAPSP 1050
Cdd:PHA03247 2767 PAPAPPAAPAAGPPRRLTRPAVASLSE-SRESLPSPWDPADPPAAVLAPAAALPPAASPAG----PLPPPTSAQPTAPPP 2841
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 1051 TPLPVQPlSLTHIGGphVATSVPlpVTWVLTAQGLLPVPV----PAVVSLPRPAGTPGPAGLLATLLPPLTEtRAAQGPR 1126
Cdd:PHA03247 2842 PPGPPPP-SLPLGGS--VAPGGD--VRRRPPSRSPAAKPAaparPPVRRLARPAVSRSTESFALPPDQPERP-PQPQAPP 2915
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 1127 APALSSSWQPPANMNREPEPSCRTDTPAPPThALSQSPAEADGSVAFVPGEAQVAREIPEPRTSSHADPPEAEPPWSGRL 1206
Cdd:PHA03247 2916 PPQPQPQPPPPPQPQPPPPPPPRPQPPLAPT-TDPAGAGEPSGAVPQPWLGALVPGRVAVPRFRVPQPAPSREAPASSTP 2994
|
....*....
gi 578817790 1207 PAFGGVIPA 1215
Cdd:PHA03247 2995 PLTGHSLSR 3003
|
|
| SANT |
smart00717 |
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; |
401-448 |
4.00e-14 |
|
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
Pssm-ID: 197842 [Multi-domain] Cd Length: 49 Bit Score: 67.63 E-value: 4.00e-14
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 578817790 401 KGYWAPEEDAKLLQAVAKYGEQDWFKIREEVPGRSDAQCRDRYLRRLH 448
Cdd:smart00717 1 KGEWTEEEDELLIELVKKYGKNNWEKIAKELPGRTAEQCRERWRNLLK 48
|
|
| SANT |
cd00167 |
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ... |
404-447 |
1.15e-13 |
|
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.
Pssm-ID: 238096 [Multi-domain] Cd Length: 45 Bit Score: 66.44 E-value: 1.15e-13
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 578817790 404 WAPEEDAKLLQAVAKYGEQDWFKIREEVPGRSDAQCRDRYLRRL 447
Cdd:cd00167 2 WTEEEDELLLEAVKKYGKNNWEKIAKELPGRTPKQCRERWRNLL 45
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
812-1232 |
3.54e-13 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 74.97 E-value: 3.54e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 812 RKALPPRLPQAGARD--PPVHLLQASSSAQSTPGHLFPNVPAQEASKSASHKGSRRLASSRVERTLPQASLLASTGPRPK 889
Cdd:PHA03247 2572 RPAPRPSEPAVTSRArrPDAPPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPER 2651
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 890 PKTVSELLQEKRLQEAR-------AREATRGPVVLPSQLLVSSSVILQPPLPHTPHGRPAPGPTVLNVPLS-GPGAPAAA 961
Cdd:PHA03247 2652 PRDDPAPGRVSRPRRARrlgraaqASSPPQRPRRRAARPTVGSLTSLADPPPPPPTPEPAPHALVSATPLPpGPAAARQA 2731
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 962 KPGTSGSWQEAGTSAKdkrlstmqalPLAPVFSEAEGTAPAASQAPALGPGQISVSCPESGLgqSQAPAASRKQGLPEAP 1041
Cdd:PHA03247 2732 SPALPAAPAPPAVPAG----------PATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRL--TRPAVASLSESRESLP 2799
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 1042 pfLPAAPSPTPLPVQPLSLTHIGGPHVATSVPLPVTWVLTAQGLLPVPVPAVVSlprPAGTPGPAGLLATLLPPLTETRA 1121
Cdd:PHA03247 2800 --SPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLP---LGGSVAPGGDVRRRPPSRSPAAK 2874
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 1122 AQGPRAPALSSSWQPPANMNREPEPSCRTDTPAPPTHALSQSPAEAdgsvafvPGEAQVAREIPEPRTSSHADPPEAEPP 1201
Cdd:PHA03247 2875 PAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQ-------PQPPPPPQPQPPPPPPPRPQPPLAPTT 2947
|
410 420 430
....*....|....*....|....*....|.
gi 578817790 1202 WSGRLPAFGGVIPAtePRGTPGSPSGTQEPR 1232
Cdd:PHA03247 2948 DPAGAGEPSGAVPQ--PWLGALVPGRVAVPR 2976
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
812-1307 |
8.42e-13 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 73.82 E-value: 8.42e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 812 RKALPPRLPQA--GARDPPvHLLQASSSAQSTPGHLFPNVPAQEASKSASH-------KGSRRLASSRV---ERTLPQAS 879
Cdd:PHA03247 2481 RRPAEARFPFAagAAPDPG-GGGPPDPDAPPAPSRLAPAILPDEPVGEPVHprmltwiRGLEELASDDAgdpPPPLPPAA 2559
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 880 LLASTG-----PRPKPKTVSELLQEKRLQEARAREATRG--PVVLPSQLLVSSSVILQPPLPHTPHgRPAPGPTVLNVPL 952
Cdd:PHA03247 2560 PPAAPDrsvppPRPAPRPSEPAVTSRARRPDAPPQSARPraPVDDRGDPRGPAPPSPLPPDTHAPD-PPPPSPSPAANEP 2638
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 953 SGPGaPAAAKPGTSGSWQEAGTSAKDKRLSTMQALPLAPVFSEAEGTAPAASqaPALGPGQISVSCPESGLGQSQAP-AA 1031
Cdd:PHA03247 2639 DPHP-PPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAAR--PTVGSLTSLADPPPPPPTPEPAPhAL 2715
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 1032 SRKQGLPEAP-------PFLPAAPSPTPLPVQPLSlthIGGPHVATSVPLPVTWVLTAQGLLPVPVPAVvSLPRPAGTP- 1103
Cdd:PHA03247 2716 VSATPLPPGPaaarqasPALPAAPAPPAVPAGPAT---PGGPARPARPPTTAGPPAPAPPAAPAAGPPR-RLTRPAVASl 2791
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 1104 GPAGLLATLLPPLTETRAAQGPRAPALSSSWQPPANmnrEPEPSCRTDTPAPPTHALSQSPAEADGSVAfvPGeAQVARE 1183
Cdd:PHA03247 2792 SESRESLPSPWDPADPPAAVLAPAAALPPAASPAGP---LPPPTSAQPTAPPPPPGPPPPSLPLGGSVA--PG-GDVRRR 2865
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 1184 IP------------EPRTSSHADPPEAEPPWSGRLPAFGgviPATEPRGTPGSPSGTQEPRGPLGLEKLPLRQPGPEKGA 1251
Cdd:PHA03247 2866 PPsrspaakpaapaRPPVRRLARPAVSRSTESFALPPDQ---PERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPP 2942
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|....*.
gi 578817790 1252 LDLEKPPLPQPGPEKGALDlgllsqegeaatqQWLGGQRGVRVPLLGSRLPYQPPA 1307
Cdd:PHA03247 2943 LAPTTDPAGAGEPSGAVPQ-------------PWLGALVPGRVAVPRFRVPQPAPS 2985
|
|
| Myb_DNA-binding |
pfam00249 |
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ... |
401-447 |
2.37e-12 |
|
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.
Pssm-ID: 459731 [Multi-domain] Cd Length: 46 Bit Score: 62.52 E-value: 2.37e-12
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 578817790 401 KGYWAPEEDAKLLQAVAKYGEqDWFKIREEVPGRSDAQCRDRYLRRL 447
Cdd:pfam00249 1 RGPWTPEEDELLLEAVEKLGN-RWKKIAKLLPGRTDNQCKNRWQNYL 46
|
|
| Myb_DNA-bind_6 |
pfam13921 |
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ... |
404-457 |
3.28e-11 |
|
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.
Pssm-ID: 372817 [Multi-domain] Cd Length: 60 Bit Score: 60.02 E-value: 3.28e-11
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 578817790 404 WAPEEDAKLLQAVAKYGeQDWFKIREEVPGRSDAQCRDRYLRRLHFSLKKGRWN 457
Cdd:pfam13921 1 WTEEEDEKLLKLVEKYG-NDWKQIAKELGRRTPKQCFDRWRRKLNPKISRGPWS 53
|
|
| PHA03378 |
PHA03378 |
EBNA-3B; Provisional |
901-1267 |
5.12e-10 |
|
EBNA-3B; Provisional
Pssm-ID: 223065 [Multi-domain] Cd Length: 991 Bit Score: 64.32 E-value: 5.12e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 901 RLQEARAREATRGPVVL----PSQLLVSSSVILQPPLPHTPHgRPAPGPTVLNVPLSGPGAPAAAKPGTSGSWQEAGTSA 976
Cdd:PHA03378 437 RTEQPRATPHSQAPTVVlhrpPTQPLEGPTGPLSVQAPLEPW-QPLPHPQVTPVILHQPPAQGVQAHGSMLDLLEKDDED 515
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 977 KDKRLSTMQALPLAP----------VFSE---AEGTAPAASQA------PALGPGQISV-------------SCPESGLG 1024
Cdd:PHA03378 516 MEQRVMATLLPPSPPqpragrrapcVYTEdldIESDEPASTEPvhdqllPAPGLGPLQIqpltspttsqlasSAPSYAQT 595
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 1025 QSQAPAASRKQGLPEAPPFLPA--APSPTPLPVQPLSLTHIGGPHVATSVPLPVTWVLTAQGLLPVPVPAVVSLPRPAGT 1102
Cdd:PHA03378 596 PWPVPHPSQTPEPPTTQSHIPEtsAPRQWPMPLRPIPMRPLRMQPITFNVLVFPTPHQPPQVEITPYKPTWTQIGHIPYQ 675
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 1103 PGPAGLLATLLPPLTETRAAQGPRAPALSSSWQPPANMNREPEPSCRTDTPAPPTHALSQSPAEADGSV---AFVPGEAQ 1179
Cdd:PHA03378 676 PSPTGANTMLPIQWAPGTMQPPPRAPTPMRPPAAPPGRAQRPAAATGRARPPAAAPGRARPPAAAPGRArppAAAPGRAR 755
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 1180 VAREIPEPRTSSHADPPEAEPpwsgRLPAFGGVIPATEPRgtpGSPSGTQEPRGPLGLEKLPLRQPGPEKGALDLEKPPL 1259
Cdd:PHA03378 756 PPAAAPGRARPPAAAPGAPTP----QPPPQAPPAPQQRPR---GAPTPQPPPQAGPTSMQLMPRAAPGQQGPTKQILRQL 828
|
....*...
gi 578817790 1260 PQPGPEKG 1267
Cdd:PHA03378 829 LTGGVKRG 836
|
|
| Myb_DNA-bind_6 |
pfam13921 |
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ... |
297-357 |
2.30e-08 |
|
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.
Pssm-ID: 372817 [Multi-domain] Cd Length: 60 Bit Score: 51.93 E-value: 2.30e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 578817790 297 WSREEEERLQAIAAAHGhLEWQKIAEELGtSRSAFQCLQKFQQHNKA-LKRKEWTEEEDRML 357
Cdd:pfam13921 1 WTEEEDEKLLKLVEKYG-NDWKQIAKELG-RRTPKQCFDRWRRKLNPkISRGPWSKEEDQRL 60
|
|
| PLN03091 |
PLN03091 |
hypothetical protein; Provisional |
399-502 |
2.69e-08 |
|
hypothetical protein; Provisional
Pssm-ID: 215570 [Multi-domain] Cd Length: 459 Bit Score: 58.06 E-value: 2.69e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 399 LKKGYWAPEEDAKLLQAVAKYGEQDWfkirEEVPGRSDAQ-----CRDRYLRRLHFSLKKGRWNLKEEEQLIELIEKYGv 473
Cdd:PLN03091 12 LRKGLWSPEEDEKLLRHITKYGHGCW----SSVPKQAGLQrcgksCRLRWINYLRPDLKRGTFSQQEENLIIELHAVLG- 86
|
90 100
....*....|....*....|....*....
gi 578817790 474 GHWAKIASELPHRSGSQCLSKWKIMMGKK 502
Cdd:PLN03091 87 NRWSQIAAQLPGRTDNEIKNLWNSCLKKK 115
|
|
| SANT |
smart00717 |
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; |
294-342 |
2.73e-08 |
|
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
Pssm-ID: 197842 [Multi-domain] Cd Length: 49 Bit Score: 51.46 E-value: 2.73e-08
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 578817790 294 KQEWSREEEERLQAIAAAHGHLEWQKIAEELGTsRSAFQCLQKFQQHNK 342
Cdd:smart00717 1 KGEWTEEEDELLIELVKKYGKNNWEKIAKELPG-RTAEQCRERWRNLLK 48
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
814-1200 |
5.24e-08 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 57.69 E-value: 5.24e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 814 ALPPRLPQAGARDPPVhlLQASSSAQSTPghlfPNVPAQEASKSASHKGSRRLASSrvertlPQASLLASTGPRPKPKTV 893
Cdd:PRK07764 380 RLERRLGVAGGAGAPA--AAAPSAAAAAP----AAAPAPAAAAPAAAAAPAPAAAP------QPAPAPAPAPAPPSPAGN 447
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 894 SELLQEKRLQEARAREATRGPVVLPSQllvssSVILQPPLPHTPHGRPAPGPTVLNVPLSGPGAPAAAKPgtSGSWQEAG 973
Cdd:PRK07764 448 APAGGAPSPPPAAAPSAQPAPAPAAAP-----EPTAAPAPAPPAAPAPAAAPAAPAAPAAPAGADDAATL--RERWPEIL 520
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 974 TSAKDKRLSTMQAL---------------------PLAPVFSEAE-----------------------GTAPAASQAPAL 1009
Cdd:PRK07764 521 AAVPKRSRKTWAILlpeatvlgvrgdtlvlgfstgGLARRFASPGnaevlvtalaeelggdwqveavvGPAPGAAGGEGP 600
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 1010 GPGQISVSCPESGLGQSQAPAASRKQGLPEAPPFLPAAPSPTPLPVQPLSLTHIGGPHVATSVPLPVTWVLTAQGLLPV- 1088
Cdd:PRK07764 601 PAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAa 680
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 1089 PVPAVVSLPRPAGTPGPAGLLATLLPPlteTRAAQGPRAPAlsSSWQPPANMNREPEPSCRTDTPAPPTHALSQSPAEAD 1168
Cdd:PRK07764 681 PPPAPAPAAPAAPAGAAPAQPAPAPAA---TPPAGQADDPA--AQPPQAAQGASAPSPAADDPVPLPPEPDDPPDPAGAP 755
|
410 420 430
....*....|....*....|....*....|..
gi 578817790 1169 GSVAFVPGEAQVAREIPEPRTSSHADPPEAEP 1200
Cdd:PRK07764 756 AQPPPPPAPAPAAAPAAAPPPSPPSEEEEMAE 787
|
|
| SANT |
smart00717 |
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; |
346-397 |
1.44e-07 |
|
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
Pssm-ID: 197842 [Multi-domain] Cd Length: 49 Bit Score: 49.14 E-value: 1.44e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 578817790 346 RKEWTEEEDRMLTQLVQEMRVGShipYRRIVYYMEGRDSMQLIYRWTKSLDP 397
Cdd:smart00717 1 KGEWTEEEDELLIELVKKYGKNN---WEKIAKELPGRTAEQCRERWRNLLKP 49
|
|
| SANT_CDC5_II |
cd11659 |
SANT/myb-like DNA-binding domain of Cell Division Cycle 5-Like Protein repeat II; In humans, ... |
290-339 |
1.64e-07 |
|
SANT/myb-like DNA-binding domain of Cell Division Cycle 5-Like Protein repeat II; In humans, cell division cycle 5-like protein (CDC5) functions in pre-mRNA splicing in cell cycle control. The DNA-binding, myb-like domain of CDC5 is a member of the SANT/myb group. SANT is named after 'SWI3, ADA2, N-CoR and TFIIIB', several factors that share this domain. The SANT domain resembles the 3 alpha-helix bundle of DNA-binding Myb domains and is found in a diverse set of proteins.
Pssm-ID: 212557 [Multi-domain] Cd Length: 53 Bit Score: 49.23 E-value: 1.64e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 578817790 290 PSINKQEWSREEEERLQAIaAAHGHLEWQKIAEELGtsRSAFQCLQKFQQ 339
Cdd:cd11659 1 PSIKKTEWTREEDEKLLHL-AKLLPTQWRTIAPIVG--RTAQQCLERYNK 47
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
820-1227 |
2.99e-07 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 55.56 E-value: 2.99e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 820 PQAGARDPPVHLLQASSSAQSTPGHLFPNVPAQEASKSASHKGSRRLASSRvERTLPQASLLASTGPRPKPKTVSELLQE 899
Cdd:PHA03307 24 PPATPGDAADDLLSGSQGQLVSDSAELAAVTVVAGAAACDRFEPPTGPPPG-PGTEAPANESRSTPTWSLSTLAPASPAR 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 900 KRLQEARAREATRGPVVLPSQLLVSSSVilQPPLPHTPHGRPAPGPTVLNVPLSGPGAPAAAKPGTSGSWQEAGTSAKDK 979
Cdd:PHA03307 103 EGSPTPPGPSSPDPPPPTPPPASPPPSP--APDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPE 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 980 RLSTMQALPLAPVFSEAEGTAPAASQAPALGPGQISVSCPESGLGQSQA---------PAASRKQGLPEAPPFLPAAPSP 1050
Cdd:PHA03307 181 ETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAAddagasssdSSSSESSGCGWGPENECPLPRP 260
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 1051 TPLPVQPLSLTHIgGPHVATSVPLPVTWVLTAQGLLPVPVPAVVSLPRPAGTPGPAGLLATLLPPLTETRAAQGP-RAPA 1129
Cdd:PHA03307 261 APITLPTRIWEAS-GWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSEsSRGA 339
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 1130 LSSSWQPPANMNREPEPSCRTDTPAPPTHALSQSPAEADGSVAFVPGEAQVAREIPEPRTSSHADPPEAEPPWSGRLPAF 1209
Cdd:PHA03307 340 AVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRARAAVAGRARRRDATGRFPAGRPRPSPLDA 419
|
410
....*....|....*...
gi 578817790 1210 GGVIPATEPRGTPGSPSG 1227
Cdd:PHA03307 420 GAASGAFYARYPLLTPSG 437
|
|
| REB1 |
COG5147 |
Myb superfamily proteins, including transcription factors and mRNA splicing factors ... |
256-357 |
2.99e-07 |
|
Myb superfamily proteins, including transcription factors and mRNA splicing factors [Transcription / RNA processing and modification / Cell division and chromosome partitioning];
Pssm-ID: 227476 [Multi-domain] Cd Length: 512 Bit Score: 54.79 E-value: 2.99e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 256 NRLDShDWEKISNINFE------GSRSAEEIRKFWQNSEHPSINKQEWSREEEERLQAIAAAHGHLeWQKIAEELGtSRS 329
Cdd:COG5147 29 EDLKA-LVKKLGPNNWSkvasllISSTGKQSSNRWNNHLNPQLKKKNWSEEEDEQLIDLDKELGTQ-WSTIADYKD-RRT 105
|
90 100
....*....|....*....|....*...
gi 578817790 330 AFQCLQKFQQHNKALKRKEWTEEEDRML 357
Cdd:COG5147 106 AQQCVERYVNTLEDLSSTHDSKLQRRNE 133
|
|
| SANT |
cd00167 |
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ... |
296-340 |
3.14e-07 |
|
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.
Pssm-ID: 238096 [Multi-domain] Cd Length: 45 Bit Score: 47.96 E-value: 3.14e-07
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 578817790 296 EWSREEEERLQAIAAAHGHLEWQKIAEELGTsRSAFQCLQKFQQH 340
Cdd:cd00167 1 PWTEEEDELLLEAVKKYGKNNWEKIAKELPG-RTPKQCRERWRNL 44
|
|
| DUF5585 |
pfam17823 |
Family of unknown function (DUF5585); This is a family of unknown function found in chordata. |
836-1230 |
4.44e-07 |
|
Family of unknown function (DUF5585); This is a family of unknown function found in chordata.
Pssm-ID: 465521 [Multi-domain] Cd Length: 506 Bit Score: 54.20 E-value: 4.44e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 836 SSAQSTPGHLFPNVPAQ-EASKSASHKGSRRLASSRVER----TLPQASLLASTGPrPKPKTVSELLQEKRLQEAR--AR 908
Cdd:pfam17823 11 FSLPLSESHAAPADPRHfVLNKMWNGAGKQNASGDAVPRadnkSSEQ*NFCAATAA-PAPVTLTKGTSAAHLNSTEvtAE 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 909 EATRG-----PVVLPSQLLVSSSVILQPPLPHTPHGRPAPGPTVLNVPLS-GPGAPAAAKPGTSGSwqeAGTSAKDKRLS 982
Cdd:pfam17823 90 HTPHGtdlsePATREGAADGAASRALAAAASSSPSSAAQSLPAAIAALPSeAFSAPRAAACRANAS---AAPRAAIAAAS 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 983 TMQALPLAPVFSEAEGTAPAASQAPALGPGQISVSCPESGLGQSQAPAASRKQGLPEAPPFLPAAPSPTPLPVQPLSLTH 1062
Cdd:pfam17823 167 APHAASPAPRTAASSTTAASSTTAASSAPTTAASSAPATLTPARGISTAATATGHPAAGTALAAVGNSSPAAGTVTAAVG 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 1063 IGGPHVATSVPLPVTWVLTAQGLLPVPVPAVVSLPRPAGTPGPAGLLATLLPPLTETraaQGPRAPAlsSSWQPPANMNR 1142
Cdd:pfam17823 247 TVTPAALATLAAAAGTVASAAGTINMGDPHARRLSPAKHMPSDTMARNPAAPMGAQA---QGPIIQV--STDQPVHNTAG 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 1143 EPEPSCRTDTPAPPTHALSQSPAEADGSVAFVPGEAQVAREIPEPRTSShadPPEAEPPWSGRLPAfggVIPATEPRGTP 1222
Cdd:pfam17823 322 EPTPSPSNTTLEPNTPKSVASTNLAVVTTTKAQAKEPSASPVPVLHTSM---IPEVEATSPTTQPS---PLLPTQGAAGP 395
|
....*...
gi 578817790 1223 GSPSGTQE 1230
Cdd:pfam17823 396 GILLAPEQ 403
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
930-1264 |
5.02e-07 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 54.61 E-value: 5.02e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 930 QPPLPHTPHGRPAPGPtvlnvplSGPGAPAAAKPGTSGSWQEAGT-SAKDKRLSTMQALPLAPVFSEAEGTAPAASQAPA 1008
Cdd:PRK07764 397 AAPSAAAAAPAAAPAP-------AAAAPAAAAAPAPAAAPQPAPApAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQPAPA 469
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 1009 LGPGQISVSCPESGLGQSQAPAASRKQGLPEAPPFLPAA---------------------------PSPTPLPVQP--LS 1059
Cdd:PRK07764 470 PAAAPEPTAAPAPAPPAAPAPAAAPAAPAAPAAPAGADDaatlrerwpeilaavpkrsrktwaillPEATVLGVRGdtLV 549
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 1060 LTH--------IGGPHVATSVplpVTwVLTAQGLLPVPVPAVVSLPRPAGTPGPAGLLATLLPPLTETRAAQGPRAPALS 1131
Cdd:PRK07764 550 LGFstgglarrFASPGNAEVL---VT-ALAEELGGDWQVEAVVGPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPA 625
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 1132 SSWQPPANMNREPEPSCRTDTPAPPTHALSQSPAEA-----DGSVAFVPGEAQVAREIPEPRTSSHADPPEAEPPWSGRL 1206
Cdd:PRK07764 626 APAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDasdggDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAP 705
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*...
gi 578817790 1207 PAFGGVIPATEPRGTPGSPSGTQEPRGPLGLEKLPLRQPGPEKGALDLEKPPLPQPGP 1264
Cdd:PRK07764 706 AATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPA 763
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
876-1248 |
5.05e-07 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 54.77 E-value: 5.05e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 876 PQASLLASTGPRPKPKTVSELLQEKRLQEARAREATRGPVVLpsqllVSSSVILQP---PLPHTP-HGRPAPGPTVLNVP 951
Cdd:pfam03154 189 PGTTQAATAGPTPSAPSVPPQGSPATSQPPNQTQSTAAPHTL-----IQQTPTLHPqrlPSPHPPlQPMTQPPPPSQVSP 263
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 952 LSGPGAPAAAKPGTSGSWQEAGTSAKDKRLSTmQALPLAPVFSEAEGTAPAASQAPalgpgqisvscpesglGQSQApaa 1031
Cdd:pfam03154 264 QPLPQPSLHGQMPPMPHSLQTGPSHMQHPVPP-QPFPLTPQSSQSQVPPGPSPAAP----------------GQSQQ--- 323
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 1032 srkqgLPEAPPFLPAAPSPTPLPVQPLSLTHIGGPHVATSVPLPVTWVLTAQG-LLPVPVPAVVSLPRPAGTPGPAGLLA 1110
Cdd:pfam03154 324 -----RIHTPPSQSQLQSQQPPREQPLPPAPLSMPHIKPPPTTPIPQLPNPQShKHPPHLSGPSPFQMNSNLPPPPALKP 398
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 1111 TLLPPLTETRAAQGPRAPALSSSWQPPANMNREPEPSCRTDTPA-----PPTHALSQSPAEAD-GSVAFVPGEAQVAREI 1184
Cdd:pfam03154 399 LSSLSTHHPPSAHPPPLQLMPQSQQLPPPPAQPPVLTQSQSLPPpaashPPTSGLHQVPSQSPfPQHPFVPGGPPPITPP 478
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 1185 PEPRTSSHADPPEAEPPWSGRlPAFGGVIPATEPRGTPG------SPSGTQEPRGPlgleKLPLRQPGPE 1248
Cdd:pfam03154 479 SGPPTSTSSAMPGIQPPSSAS-VSSSGPVPAAVSCPLPPvqikeeALDEAEEPESP----PPPPRSPSPE 543
|
|
| REB1 |
COG5147 |
Myb superfamily proteins, including transcription factors and mRNA splicing factors ... |
334-453 |
5.18e-07 |
|
Myb superfamily proteins, including transcription factors and mRNA splicing factors [Transcription / RNA processing and modification / Cell division and chromosome partitioning];
Pssm-ID: 227476 [Multi-domain] Cd Length: 512 Bit Score: 54.02 E-value: 5.18e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 334 LQKFQQHNKALKRKE--WTEEEDRMLTQLVQEM------RVGSHIPYRrivyyMEGRDSMqliyRWTKSLDPGLKKGYWA 405
Cdd:COG5147 6 NKELQIKLMQTKRKGgsWKRTEDEDLKALVKKLgpnnwsKVASLLISS-----TGKQSSN----RWNNHLNPQLKKKNWS 76
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 578817790 406 PEEDAKLLQAVAKYGEQdWFKIREEVPGRSDAQCRDRYLRRLHFSLKK 453
Cdd:COG5147 77 EEEDEQLIDLDKELGTQ-WSTIADYKDRRTAQQCVERYVNTLEDLSST 123
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
878-1234 |
1.52e-06 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 53.25 E-value: 1.52e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 878 ASLLASTGPRPKPKTVSELLQEKRLQEARAREATRGPVVLPSQLLVSSSVIlqPPLPHTPHGRPAPGPTVLNVPLSGPGA 957
Cdd:PHA03307 57 AGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPT--PPGPSSPDPPPPTPPPASPPPSPAPDL 134
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 958 PAAAKPGTSGSwqeagtsakdKRLSTMQALPLAPVFSEAEGTAPAASQAPALGPGQISVSCPESG---LGQSQAPAASRK 1034
Cdd:PHA03307 135 SEMLRPVGSPG----------PPPAASPPAAGASPAAVASDAASSRQAALPLSSPEETARAPSSPpaePPPSTPPAAASP 204
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 1035 QGLPEAPPFLPAAPSPTPLPVQPLSLTHIGGPHVATSVPLPVTwVLTAQGLLPVPVPAVVSLPRPAGTPGPAGLLATLLP 1114
Cdd:PHA03307 205 RPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGC-GWGPENECPLPRPAPITLPTRIWEASGWNGPSSRPG 283
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 1115 PLTETRAAQGPRAPALSSSwqppanmnrepepSCRTDTPAPPTHALSQSPAEADGSVAFVPGEAQVAREIPEPRTSSHAD 1194
Cdd:PHA03307 284 PASSSSSPRERSPSPSPSS-------------PGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRS 350
|
330 340 350 360
....*....|....*....|....*....|....*....|
gi 578817790 1195 PPEAEPPwsgrlPAFGGVIPATEPRGTPGSPSGTQEPRGP 1234
Cdd:PHA03307 351 PSPSRPP-----PPADPSSPRKRPRPSRAPSSPAASAGRP 385
|
|
| Myb_DNA-bind_6 |
pfam13921 |
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ... |
349-412 |
3.31e-06 |
|
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.
Pssm-ID: 372817 [Multi-domain] Cd Length: 60 Bit Score: 45.76 E-value: 3.31e-06
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 578817790 349 WTEEEDRMLTQLVQEMrvgsHIPYRRIVYYMEGRDSMQLIYRWTKSLDPGLKKGYWAPEEDAKL 412
Cdd:pfam13921 1 WTEEEDEKLLKLVEKY----GNDWKQIAKELGRRTPKQCFDRWRRKLNPKISRGPWSKEEDQRL 60
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
960-1170 |
4.24e-06 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 51.42 E-value: 4.24e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 960 AAKPGTSGSWQEAGTSAKDKRLSTMQAL----PLAPVFSEAEGTAPAASQAPALGPGQISVSCPESGLGQSQAPAASRKQ 1035
Cdd:PRK12323 362 AFRPGQSGGGAGPATAAAAPVAQPAPAAaapaAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASA 441
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 1036 GLPEAPPFLPAAPSPTPLPVQPLSLTHIGGPHVATSVPLPVTWVLTAQGLLPVPVPAVVSLPRPAGTPGP----AGLLAT 1111
Cdd:PRK12323 442 RGPGGAPAPAPAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPPWEELPPEFASPAPaqpdAAPAGW 521
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 578817790 1112 LLPPLTETRAAQGPRAPALSSSWQPPANMNREPEPSCRTDTPAPPTHALSQSPAEADGS 1170
Cdd:PRK12323 522 VAESIPDPATADPDDAFETLAPAPAAAPAPRAAAATEPVVAPRPPRASASGLPDMFDGD 580
|
|
| SANT |
cd00167 |
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric ... |
470-496 |
4.31e-06 |
|
'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is also found in regulatory transcriptional repressor complexes where it also binds DNA.
Pssm-ID: 238096 [Multi-domain] Cd Length: 45 Bit Score: 44.87 E-value: 4.31e-06
10 20
....*....|....*....|....*..
gi 578817790 470 KYGVGHWAKIASELPHRSGSQCLSKWK 496
Cdd:cd00167 16 KYGKNNWEKIAKELPGRTPKQCRERWR 42
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
1000-1270 |
4.96e-06 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 51.39 E-value: 4.96e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 1000 APAASQAPAlGPGQISVSCPESGLGQSQAPAASRKQGLPEAPPFLPAAPSPTPLPVQPLSLTHIGGPHVAtsvPLPVTWV 1079
Cdd:PRK07003 361 AVTGGGAPG-GGVPARVAGAVPAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAA---PAPPATA 436
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 1080 LTAQGLLPVPVPAVVSLPRPAGTPGPAGLLATLLPPLTETRAAQGPRAPALSSswqppanmnREPEPSCrtdtpAPPTHA 1159
Cdd:PRK07003 437 DRGDDAADGDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAA---------FEPAPRA-----AAPSAA 502
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 1160 LSQSPAEADGSVAFVPGEAQVAREIPEPRTSShADPPEAEPPWSGrlpafGGVIPATEPRGTPGSPSGTQEPRGPLGLEK 1239
Cdd:PRK07003 503 TPAAVPDARAPAAASREDAPAAAAPPAPEARP-PTPAAAAPAARA-----GGAAAALDVLRNAGMRVSSDRGARAAAAAK 576
|
250 260 270
....*....|....*....|....*....|.
gi 578817790 1240 LPLRQPGPEKGALDLEKPPLPQPGPEKGALD 1270
Cdd:PRK07003 577 PAAAPAAAPKPAAPRVAVQVPTPRARAATGD 607
|
|
| SANT |
smart00717 |
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains; |
470-496 |
5.70e-06 |
|
SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains;
Pssm-ID: 197842 [Multi-domain] Cd Length: 49 Bit Score: 44.52 E-value: 5.70e-06
10 20
....*....|....*....|....*..
gi 578817790 470 KYGVGHWAKIASELPHRSGSQCLSKWK 496
Cdd:smart00717 18 KYGKNNWEKIAKELPGRTAEQCRERWR 44
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
987-1215 |
8.81e-06 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 50.26 E-value: 8.81e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 987 LPLAPVFSEAEGTAPAASQAPALGPG----QISVSCPESGLGQSQAPAASRKQGLPEAPPFLPAAPSPTPLPVQPLSLTH 1062
Cdd:PRK12323 361 LAFRPGQSGGGAGPATAAAAPVAQPApaaaAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQAS 440
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 1063 IGGPhVATSVPLPVtwvltaqgllPVPVPAVVSLPRPAGTPGPAglLATLLPPLTETRAAQGPRAPALSSSWQPPANMNR 1142
Cdd:PRK12323 441 ARGP-GGAPAPAPA----------PAAAPAAAARPAAAGPRPVA--AAAAAAPARAAPAAAPAPADDDPPPWEELPPEFA 507
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 578817790 1143 EPEPSCRTDTPAPPTHALSQSPAEADGSVAF-VPGEAQVAREIPEPRTSSHADPPEAEPPWS--GRLPAFGGVIPA 1215
Cdd:PRK12323 508 SPAPAQPDAAPAGWVAESIPDPATADPDDAFeTLAPAPAAAPAPRAAAATEPVVAPRPPRASasGLPDMFDGDWPA 583
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
931-1138 |
9.92e-06 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 50.26 E-value: 9.92e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 931 PPLPHTPHGRPAPG---PTVLNVPLSGPGAPAAAKPGTSGSWQEAGtSAKDKRLSTMQALPLApvfSEAEGTAPAASQAP 1007
Cdd:PRK12323 375 ATAAAAPVAQPAPAaaaPAAAAPAPAAPPAAPAAAPAAAAAARAVA-AAPARRSPAPEALAAA---RQASARGPGGAPAP 450
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 1008 ALGPGQISVSCPESGLGQSQAPAASRKQGLPEAPPFLPAAPSPTPLPVQPLSLTHIGGPHVATSVPLPVTWVLTAqglLP 1087
Cdd:PRK12323 451 APAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPPWEELPPEFASPAPAQPDAAPAGWVAES---IP 527
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 578817790 1088 VPVPAVVSLPRPAGTPGPAGLLATLLPPLTETRAAqgPRAPALSSSWQPPA 1138
Cdd:PRK12323 528 DPATADPDDAFETLAPAPAAAPAPRAAAATEPVVA--PRPPRASASGLPDM 576
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
930-1272 |
1.69e-05 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 49.94 E-value: 1.69e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 930 QPPLPHTPHGRPAPGPTVLNVPLSGPGAPAAAKPGTSGSWQEAGT---SAKDKRLSTMQALPLAPVFSEaegtaPAASQA 1006
Cdd:PHA03247 2414 QPDPPGPPDVRFVGSEEIEELPFVSPGGDVLAGLAADGDPFFARTilgAPFSLSLLLGELFPGAPVYRR-----PAEARF 2488
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 1007 P-ALGPGqisvscPESGLGQSQAPAASRKQGLPeAPPFLPAAPSPTPLPVQPLSLTH---------IGGPhvatSVPLPv 1076
Cdd:PHA03247 2489 PfAAGAA------PDPGGGGPPDPDAPPAPSRL-APAILPDEPVGEPVHPRMLTWIRgleelasddAGDP----PPPLP- 2556
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 1077 twvltaqgllPVPVPAVV--SLPRPAGTPGPAGLLAtllpplteTRAAQGPRAPALSSSWQPPANmNREPEPSCRTDTPA 1154
Cdd:PHA03247 2557 ----------PAAPPAAPdrSVPPPRPAPRPSEPAV--------TSRARRPDAPPQSARPRAPVD-DRGDPRGPAPPSPL 2617
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 1155 PPTHALSQSPAEADGSVAFVPGEAQVAREIPEPRTSSHADPPEAEPPWSGRLP--AFGGVIPATEPR------------- 1219
Cdd:PHA03247 2618 PPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLgrAAQASSPPQRPRrraarptvgslts 2697
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 578817790 1220 -GTPGSPSGTQEPRGPLGLEKLPLrQPGPEKGALDLEKPPL---PQPGPEKGALDLG 1272
Cdd:PHA03247 2698 lADPPPPPPTPEPAPHALVSATPL-PPGPAAARQASPALPAapaPPAVPAGPATPGG 2753
|
|
| Myb_DNA-binding |
pfam00249 |
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ... |
294-340 |
2.30e-05 |
|
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.
Pssm-ID: 459731 [Multi-domain] Cd Length: 46 Bit Score: 42.88 E-value: 2.30e-05
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 578817790 294 KQEWSREEEERLQAIAAAHGHlEWQKIAEELGTsRSAFQCLQKFQQH 340
Cdd:pfam00249 1 RGPWTPEEDELLLEAVEKLGN-RWKKIAKLLPG-RTDNQCKNRWQNY 45
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
903-1202 |
3.29e-05 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 48.69 E-value: 3.29e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 903 QEARAREATRGPVVLPSQLLVSSSVILQPPLPHTPHGRPAPGPTVLNVPLSGPGAPAAAKPGTSGSWQEaGTSAKDKRLS 982
Cdd:PRK07003 372 VPARVAGAVPAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPATADRGD-DAADGDAPVP 450
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 983 TMQALPLAPVFSEAEGTA-PAASQAPALGPGqisvscpesglgqSQAPAASRKQGLPEAPPFLPAAPSPTPLPVQPLSLT 1061
Cdd:PRK07003 451 AKANARASADSRCDERDAqPPADSGSASAPA-------------SDAPPDAAFEPAPRAAAPSAATPAAVPDARAPAAAS 517
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 1062 HIGGPHVAtSVPLPvtwvltaqgLLPVPVPAVVSLPRPAGTPGPAGLLATLLPPLTETRAAQGPRAPALSSSWQPPANMN 1141
Cdd:PRK07003 518 REDAPAAA-APPAP---------EARPPTPAAAAPAARAGGAAAALDVLRNAGMRVSSDRGARAAAAAKPAAAPAAAPKP 587
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 578817790 1142 REPEPSCRTDTPAPPTHALSQSPAEAdgsvafvpgeaqvareipePRTSSHADPPEAEPPW 1202
Cdd:PRK07003 588 AAPRVAVQVPTPRARAATGDAPPNGA-------------------ARAEQAAESRGAPPPW 629
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
1064-1302 |
3.90e-05 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 48.33 E-value: 3.90e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 1064 GGPHVATSVPLPVTWVLtaqgllPVPVPAVVSLPRPAGTPGPAGLLATLLPPLTETRAAQGPRAPALSSSWQPPANMNRE 1143
Cdd:PRK12323 370 GGAGPATAAAAPVAQPA------PAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARG 443
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 1144 PEPSCRTDTPAPPTHALSQSPAEADgsvafvpgeaqvareiPEPRTSSHADPPEAEPPWSGRLPAFGGVIPATEPRGTPG 1223
Cdd:PRK12323 444 PGGAPAPAPAPAAAPAAAARPAAAG----------------PRPVAAAAAAAPARAAPAAAPAPADDDPPPWEELPPEFA 507
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 1224 SPSGTQEPRGPLGLEKLPLRQPG---PEKGALDLEKPPLPQPGPEKGALDLGLLSQEGEAATQQWLGGQRGVRVPLLGSR 1300
Cdd:PRK12323 508 SPAPAQPDAAPAGWVAESIPDPAtadPDDAFETLAPAPAAAPAPRAAAATEPVVAPRPPRASASGLPDMFDGDWPALAAR 587
|
..
gi 578817790 1301 LP 1302
Cdd:PRK12323 588 LP 589
|
|
| REB1 |
COG5147 |
Myb superfamily proteins, including transcription factors and mRNA splicing factors ... |
399-495 |
4.68e-05 |
|
Myb superfamily proteins, including transcription factors and mRNA splicing factors [Transcription / RNA processing and modification / Cell division and chromosome partitioning];
Pssm-ID: 227476 [Multi-domain] Cd Length: 512 Bit Score: 47.86 E-value: 4.68e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 399 LKKGYWAPEEDAKLLQAVAKYGEQDWFKIREEVPGRSDAQCRDRYLRRLHFSLKKGRWNLKEEEQLIELIEKYGVgHWAK 478
Cdd:COG5147 18 RKGGSWKRTEDEDLKALVKKLGPNNWSKVASLLISSTGKQSSNRWNNHLNPQLKKKNWSEEEDEQLIDLDKELGT-QWST 96
|
90
....*....|....*..
gi 578817790 479 IASELPHRSGSQCLSKW 495
Cdd:COG5147 97 IADYKDRRTAQQCVERY 113
|
|
| Herpes_BLLF1 |
pfam05109 |
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ... |
931-1216 |
4.74e-05 |
|
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.
Pssm-ID: 282904 [Multi-domain] Cd Length: 886 Bit Score: 47.99 E-value: 4.74e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 931 PPLPHTPHGRPAP---GPTVLNVPLSGP---GAPAAAKPGT-SGSWQEAGTSAKDKRLSTmqalplaPVFSEAEGTAPAA 1003
Cdd:pfam05109 449 PSSTHVPTNLTAPastGPTVSTADVTSPtpaGTTSGASPVTpSPSPRDNGTESKAPDMTS-------PTSAVTTPTPNAT 521
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 1004 SQAPALGPGQISVSCPESGlgqSQAPAASRKQGLPEAPPFLPAAPSPTPLPVQP-LSLThigGPHVATSVPLPVTWVLTA 1082
Cdd:pfam05109 522 SPTPAVTTPTPNATSPTLG---KTSPTSAVTTPTPNATSPTPAVTTPTPNATIPtLGKT---SPTSAVTTPTPNATSPTV 595
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 1083 QGLLP------------VPVPAVVSLPRPAGTPGPAGLLATLLppltETRAAQGPRAPALSSSWQPPANMNR-------- 1142
Cdd:pfam05109 596 GETSPqanttnhtlggtSSTPVVTSPPKNATSAVTTGQHNITS----SSTSSMSLRPSSISETLSPSTSDNStshmpllt 671
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 1143 EPEPS-----------------CRTDTPAPPTHALSQSPAEADGSVAFVPGEAQVAREIPePRTSSHADPPEAEPPWSGR 1205
Cdd:pfam05109 672 SAHPTggenitqvtpaststhhVSTSSPAPRPGTTSQASGPGNSSTSTKPGEVNVTKGTP-PKNATSPQAPSGQKTAVPT 750
|
330
....*....|.
gi 578817790 1206 LPAFGGVIPAT 1216
Cdd:pfam05109 751 VTSTGGKANST 761
|
|
| SANT_CDC5_II |
cd11659 |
SANT/myb-like DNA-binding domain of Cell Division Cycle 5-Like Protein repeat II; In humans, ... |
397-443 |
5.69e-05 |
|
SANT/myb-like DNA-binding domain of Cell Division Cycle 5-Like Protein repeat II; In humans, cell division cycle 5-like protein (CDC5) functions in pre-mRNA splicing in cell cycle control. The DNA-binding, myb-like domain of CDC5 is a member of the SANT/myb group. SANT is named after 'SWI3, ADA2, N-CoR and TFIIIB', several factors that share this domain. The SANT domain resembles the 3 alpha-helix bundle of DNA-binding Myb domains and is found in a diverse set of proteins.
Pssm-ID: 212557 [Multi-domain] Cd Length: 53 Bit Score: 41.91 E-value: 5.69e-05
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 578817790 397 PGLKKGYWAPEEDAKLLQAVAKYGEQdWFKIREEVpGRSDAQCRDRY 443
Cdd:cd11659 1 PSIKKTEWTREEDEKLLHLAKLLPTQ-WRTIAPIV-GRTAQQCLERY 45
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
559-1059 |
6.24e-05 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 48.01 E-value: 6.24e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 559 LLSPQYMVPDMDLWVPARQSTSQPWRGGAGAWLGGPAAslsPPKGSSASQGGSKEASTTAAAPgeetsPVQVPARAHGPV 638
Cdd:PHA03247 2554 PLPPAAPPAAPDRSVPPPRPAPRPSEPAVTSRARRPDA---PPQSARPRAPVDDRGDPRGPAP-----PSPLPPDTHAPD 2625
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 639 PRSAQASHSADTRPAGAEKQALEGGRRLLTVPVETVLRVLRANTAARSCTQKEQLRQPPLPTSSPGVSSGDSVARSHVQw 718
Cdd:PHA03247 2626 PPPPSPSPAANEPDPHPPPTVPPPERPRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPP- 2704
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 719 lrHRATQSGQRRWRHALHRRLLNRRLLLAVTPWVGDVVVPCTQASqrPAVVQTQADGLREQLQQARLASTPvftlftqlf 798
Cdd:PHA03247 2705 --PPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAG--PATPGGPARPARPPTTAGPPAPAP--------- 2771
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 799 hidtagclevvrerKALPPRLPQAGARDPPVhllqaSSSAQSTPGHLFPNVPAqEASKSASHKGSRRLASSRVERTLPQA 878
Cdd:PHA03247 2772 --------------PAAPAAGPPRRLTRPAV-----ASLSESRESLPSPWDPA-DPPAAVLAPAAALPPAASPAGPLPPP 2831
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 879 SLLASTGPRPKPKTVSELLQEKRLQEARAREATRGPVVLPSQLLVSSSvilQPPLPHTPhgRPAPGPTVLNVPLSGPGAP 958
Cdd:PHA03247 2832 TSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPA---RPPVRRLA--RPAVSRSTESFALPPDQPE 2906
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 959 AAAKPgtsgswqEAGTSAKDKRLSTMQALPLAPVFSEAEGTAPAASQAPALGPGQISVSCPESGLGQ--SQAPAASRKQG 1036
Cdd:PHA03247 2907 RPPQP-------QAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGAlvPGRVAVPRFRV 2979
|
490 500
....*....|....*....|...
gi 578817790 1037 LPEAPPFLPAAPSPTPLPVQPLS 1059
Cdd:PHA03247 2980 PQPAPSREAPASSTPPLTGHSLS 3002
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
938-1156 |
7.36e-05 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 47.29 E-value: 7.36e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 938 HGRPAPGPTVLNVPLSGPGAPAAAKPGTSGSWQEAGTSAKDKRlstmqalplAPVFSEAEGTAPAASQAPALGPGQISVS 1017
Cdd:PRK07764 590 PAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGA---------AAAPAEASAAPAPGVAAPEHHPKHVAVP 660
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 1018 CPESGLGQSQAPAASRKQGLPEAPPFLPAAPSPTPLPVQPLSLTHIGGPHVATSVPLPVTWVLTAQGLLPVPVPAVVSLP 1097
Cdd:PRK07764 661 DASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVP 740
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 578817790 1098 RPaGTPGPAGLLATLLPPLTETRAAQGPRAPALSSSWQPPAnmnrEPEPSCRTDTPAPP 1156
Cdd:PRK07764 741 LP-PEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPS----EEEEMAEDDAPSMD 794
|
|
| PHA03378 |
PHA03378 |
EBNA-3B; Provisional |
874-1209 |
1.19e-04 |
|
EBNA-3B; Provisional
Pssm-ID: 223065 [Multi-domain] Cd Length: 991 Bit Score: 46.98 E-value: 1.19e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 874 TLPQASLLASTGP----RPKPKTVSELLQEKRLQEARAREAT---RGPVVL---PSQLLVSSSVILQPPLPHTPHGRPAP 943
Cdd:PHA03378 578 TSPTTSQLASSAPsyaqTPWPVPHPSQTPEPPTTQSHIPETSaprQWPMPLrpiPMRPLRMQPITFNVLVFPTPHQPPQV 657
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 944 GPTVLNV----PLSGPGAPAAAKPGTSGSWQEAGTsakdkrlsTMQALPLAPVFSEAEGTAPAASQAPALGPGQISVSCP 1019
Cdd:PHA03378 658 EITPYKPtwtqIGHIPYQPSPTGANTMLPIQWAPG--------TMQPPPRAPTPMRPPAAPPGRAQRPAAATGRARPPAA 729
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 1020 ESGLGQSQAPAASRKQGlPEAPPFLPAAPSPTPLPVQPLSlthiGGPHVATSVPLPVTWVLTAQ----GLLPVPVPAV-- 1093
Cdd:PHA03378 730 APGRARPPAAAPGRARP-PAAAPGRARPPAAAPGRARPPA----AAPGAPTPQPPPQAPPAPQQrprgAPTPQPPPQAgp 804
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 1094 ----VSLPRPAGTPGPAGLLATLLPPLTETRAAQGPRAPALSSSwQPPANMNREPEPSCRTDT-PAPPTHALSQSPAEAD 1168
Cdd:PHA03378 805 tsmqLMPRAAPGQQGPTKQILRQLLTGGVKRGRPSLKKPAALER-QAAAGPTPSPGSGTSDKIvQAPVFYPPVLQPIQVM 883
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 578817790 1169 GSVAFV---------------PGEAQVA-----REIPEPRTSSHADPPEAEPPWSGRLPAF 1209
Cdd:PHA03378 884 RQLGSVraaaastvtqapteyTGERRGVgpmhpTDIPPSKRAKTDAYVESQPPHGGQSHSF 944
|
|
| SANT_TRF |
cd11660 |
Telomere repeat binding factor-like DNA-binding domains of the SANT/myb-like family; Human ... |
404-443 |
1.36e-04 |
|
Telomere repeat binding factor-like DNA-binding domains of the SANT/myb-like family; Human telomere repeat binding factors, TRF1 and TRF2, function as part of the 6 component shelterin complex. TRF2 binds DNA and recruits RAP1 (via binding to the RAP1 protein c-terminal (RCT)) and TIN2 in the protection of telomeres from DNA repair machinery. Metazoan shelterin consists of 3 DNA binding proteins (TRF2, TRF1, and POT1) and 3 recruited proteins that bind to one or more of these DNA-binding proteins (RAP1, TIN2, TPP1). Schizosaccharomyces pombe TAZ1 is an orthlog and binds RAP1. Human TRF1 and TRF2 bind double-stranded DNA. hTRF2 consists of a basic N-terminus, a TRF homology domain, the RAP1 binding motif (RBM), the TIN2 binding motif (TBM) and a myb-like DNA binding domain, SANT, named after 'SWI3, ADA2, N-CoR and TFIIIB', several factors that share this domain. Tandem copies of the domain bind telomeric DNA tandem repeats as part of the capping complex. The single myb-like domain of TRF-type proteins is similar to the tandem myb_like domains found in yeast RAP1.
Pssm-ID: 212558 [Multi-domain] Cd Length: 50 Bit Score: 41.01 E-value: 1.36e-04
10 20 30 40
....*....|....*....|....*....|....*....|...
gi 578817790 404 WAPEEDAKLLQAVAKYGEQDWFKIREE---VPGRSDAQCRDRY 443
Cdd:cd11660 3 WTDEEDEALVEGVEKYGVGNWAKILKDyffVNNRTSVDLKDKW 45
|
|
| Myb_DNA-bind_6 |
pfam13921 |
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, ... |
262-305 |
1.36e-04 |
|
Myb-like DNA-binding domain; This family contains the DNA binding domains from Myb proteins, as well as the SANT domain family.
Pssm-ID: 372817 [Multi-domain] Cd Length: 60 Bit Score: 41.14 E-value: 1.36e-04
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 578817790 262 DWEKISNInfEGSRSAEEIRKFWQNSEHPSINKQEWSREEEERL 305
Cdd:pfam13921 19 DWKQIAKE--LGRRTPKQCFDRWRRKLNPKISRGPWSKEEDQRL 60
|
|
| REB1 |
COG5147 |
Myb superfamily proteins, including transcription factors and mRNA splicing factors ... |
292-411 |
3.11e-04 |
|
Myb superfamily proteins, including transcription factors and mRNA splicing factors [Transcription / RNA processing and modification / Cell division and chromosome partitioning];
Pssm-ID: 227476 [Multi-domain] Cd Length: 512 Bit Score: 45.16 E-value: 3.11e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 292 INKQEWSREEEERLQAIAAAHGHLEWQKIAEELgTSRSAFQC-LQKFQQHNKALKRKEWTEEEDRMLTQLVQEMrvGSHI 370
Cdd:COG5147 18 RKGGSWKRTEDEDLKALVKKLGPNNWSKVASLL-ISSTGKQSsNRWNNHLNPQLKKKNWSEEEDEQLIDLDKEL--GTQW 94
|
90 100 110 120
....*....|....*....|....*....|....*....|.
gi 578817790 371 pyRRIVYYMEGRDSMQLIYRWTKSLDPGLKKGYWAPEEDAK 411
Cdd:COG5147 95 --STIADYKDRRTAQQCVERYVNTLEDLSSTHDSKLQRRNE 133
|
|
| REB1 |
COG5147 |
Myb superfamily proteins, including transcription factors and mRNA splicing factors ... |
233-375 |
3.50e-04 |
|
Myb superfamily proteins, including transcription factors and mRNA splicing factors [Transcription / RNA processing and modification / Cell division and chromosome partitioning];
Pssm-ID: 227476 [Multi-domain] Cd Length: 512 Bit Score: 45.16 E-value: 3.50e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 233 KQGREAEKEiQDINQLPE-----EALLGNRLDSHDWEKISNINFE----GSRSAEEIRKFWQNSEHPSINKQEWSREEEE 303
Cdd:COG5147 222 KKGETLALE-QEINEYKEkkglsRKQFCERIWSTDRDEDKFWPNIykklPYRDKKSIYKHLRRKYNIFEQRGKWTKEEEQ 300
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 578817790 304 RLQAIAAAHGHLeWQKIAEELGTSRSafQCLQKFQQHNK---ALKRKEWTEEEDRMLTQLVQEMRVGSHiPYRRI 375
Cdd:COG5147 301 ELAKLVVEHGGS-WTEIGKLLGRMPN--DCRDRWRDYVKcgdTLKRNRWSIEEEELLDKVVNEMRLEAQ-QSSRI 371
|
|
| PksD |
COG3321 |
Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites ... |
792-1319 |
5.91e-04 |
|
Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 442550 [Multi-domain] Cd Length: 1386 Bit Score: 44.48 E-value: 5.91e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 792 TLFTQLFHIDTAGCLEVVRERKALPPRLP----QAGARDPPVHLLQASSSAQSTPGHLFPNVPAQEASKSASHKGSRRLA 867
Cdd:COG3321 839 QLWVAGVPVDWSALYPGRGRRRVPLPTYPfqreDAAAALLAAALAAALAAAAALGALLLAALAAALAAALLALAAAAAAA 918
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 868 SSRVERTLPQASLLASTGPRPKPKTVSELLQEKRLQEARAREATRGPVVLPSQLLVSSSVILQPPLPHTPHGRPAPGPTV 947
Cdd:COG3321 919 LALAAAALAALLALVALAAAAAALLALAAAAAAAAAALAAAEAGALLLLAAAAAAAAAAAAAAAAAAAAAAAAAAAALAA 998
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 948 LNVPLSGPGAPAAAKPGTSGSWQEAGTSAKDKRLSTMQALPLAPVFSEAEGTAPAASQAPALGPGQISVSCPESGLGQSQ 1027
Cdd:COG3321 999 AAALALLAAAALLLAAAAAAAALLALAALLAAAAAALAAAAAAAAAAAALAALAAAAAAAAALALALAALLLLAALAELA 1078
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 1028 APAASRKQGLPEAPPFLPAAPSPTPLPVQPLSLTHIGGPHVATSVPLPVTWVLTAQGLLPVPVPAVVSLPRPAGTPGPAG 1107
Cdd:COG3321 1079 LAAAALALAAALAAAALALALAALAAALLLLALLAALALAAAAAALLALAALLAAAAAAAALAAAAAAAAALALAAAAAA 1158
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 1108 LLATLLPPLTETRAAQGPRAPALSSSWQPPANMNREPEPSCRTDTPAPPTHALSQSPAEADGSVAFVPGEAQVAREIPEP 1187
Cdd:COG3321 1159 LAAALAAALLAAAALLLALALALAAALAAALAGLAALLLAALLAALLAALLALALAALAAAAAALLAAAAAAAALALLAL 1238
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 1188 RTSSHADPPEAE-PPWSGRLPAFGGVIPATEPRGTPGSPSGTQEPRGPLGLEKLPLRQPGPEKGALDLEKPPLPQPGPEK 1266
Cdd:COG3321 1239 AAAAAAVAALAAaAAALLAALAALALLAAAAGLAALAAAAAAAAAALALAAAAAAAAAALAALLAAAAAAAAAAAAAAAA 1318
|
490 500 510 520 530
....*....|....*....|....*....|....*....|....*....|...
gi 578817790 1267 GALDLGLLSQEGEAATQQWLGGQRGVRVPLLGSRLPYQPPALCSLRALSGLLL 1319
Cdd:COG3321 1319 AALAAALLAAALAALAAAVAAALALAAAAAAAAAAAAAAAAAAALAAAAGAAA 1371
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
966-1235 |
7.10e-04 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 44.39 E-value: 7.10e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 966 SGSWQEAGTSAKDKRLSTMQALPLAPVFSEAEGTAPAASQAPALGPGQISVSCPESGlgqSQAPAASRKQGLPEAPPflP 1045
Cdd:PHA03307 37 SGSQGQLVSDSAELAAVTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLS---TLAPASPAREGSPTPPG--P 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 1046 AAPSPTPLPVQPLSLTHIGGPHVATSVPLPVTWVLTAQGllpVPVPAVVSLPRPAGTPGPAGLLATLLPPLTETRAAQGP 1125
Cdd:PHA03307 112 SSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAA---SPPAAGASPAAVASDAASSRQAALPLSSPEETARAPSS 188
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 1126 RAPALSSSWQPPANMNREPEP------SCRTDTPAPPTHALSQSPAEADGSVAFVPGEAQVARE----IPEPRTSSHADP 1195
Cdd:PHA03307 189 PPAEPPPSTPPAAASPRPPRRsspisaSASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPEnecpLPRPAPITLPTR 268
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 578817790 1196 PEAEPPWSGRLPAFGGVIPATEPRGTPGSPSGTQEPRGPL 1235
Cdd:PHA03307 269 IWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPA 308
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
1006-1307 |
1.06e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 43.82 E-value: 1.06e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 1006 APALGPGQISVSCPESGLGQSQAPAASRKQGLPEAPPflPAAPSPTPLPVQplslthigGPHVATSVPLPVTWVLTAQGL 1085
Cdd:PRK07764 385 LGVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAA--APAPAAAPQPAP--------APAPAPAPPSPAGNAPAGGAP 454
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 1086 LPVPVPAVVSLPRPAGTPGPAGLLATLLPPLTETRAAQGPRAPAlSSSWQPPANMNREPEPS-----------CRTDTPA 1154
Cdd:PRK07764 455 SPPPAAAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPAAAPAAPA-APAAPAGADDAATLRERwpeilaavpkrSRKTWAI 533
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 1155 PPTHAlsqSPAEADGSV---AFV----------PGEAQVAREIPEPRT-------------SSHADPPEAEPPWSGRLPA 1208
Cdd:PRK07764 534 LLPEA---TVLGVRGDTlvlGFStgglarrfasPGNAEVLVTALAEELggdwqveavvgpaPGAAGGEGPPAPASSGPPE 610
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 1209 FGGVIPATEPRGTPGSPSGTQEPRGPLGLEKLPLRQPGPEKGALDLEKPPLPQPGPEKGALDLGLLSQEGEAATQQWLG- 1287
Cdd:PRK07764 611 EAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAp 690
|
330 340
....*....|....*....|.
gi 578817790 1288 -GQRGVRVPLLGSRLPYQPPA 1307
Cdd:PRK07764 691 aAPAGAAPAQPAPAPAATPPA 711
|
|
| PLN03212 |
PLN03212 |
Transcription repressor MYB5; Provisional |
398-502 |
1.11e-03 |
|
Transcription repressor MYB5; Provisional
Pssm-ID: 178751 [Multi-domain] Cd Length: 249 Bit Score: 42.37 E-value: 1.11e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 398 GLKKGYWAPEEDAKLLQAVAKYGEQDWFKIREEVP-GRSDAQCRDRYLRRLHFSLKKGRWNLKEEEQLIELIEKYGvGHW 476
Cdd:PLN03212 22 GMKRGPWTVEEDEILVSFIKKEGEGRWRSLPKRAGlLRCGKSCRLRWMNYLRPSVKRGGITSDEEDLILRLHRLLG-NRW 100
|
90 100
....*....|....*....|....*.
gi 578817790 477 AKIASELPHRSGSQCLSKWKIMMGKK 502
Cdd:PLN03212 101 SLIAGRIPGRTDNEIKNYWNTHLRKK 126
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
942-1186 |
1.25e-03 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 43.77 E-value: 1.25e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 942 APGPTVLNVPLSGpGAPAAAKPGTSGSWQ-EAGTSAKDKRlstmqalPLAPVFSEAEGTAPAASQAPALGPGQISVSCPE 1020
Cdd:PHA03247 254 APAPPPVVGEGAD-RAPETARGATGPPPPpEAAAPNGAAA-------PPDGVWGAALAGAPLALPAPPDPPPPAPAGDAE 325
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 1021 SGLGQSQAPAASRKQGLPEA--PPFLPAAPSPTPLPvqPLSLTHI-GGPHVATSVPLPVTWVLTA--------------- 1082
Cdd:PHA03247 326 EEDDEDGAMEVVSPLPRPRQhyPLGFPKRRRPTWTP--PSSLEDLsAGRHHPKRASLPTRKRRSArhaatpfargpggdd 403
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 1083 QGLLPVPVPAVVSLPRPAGTPGPAGLLATLLPPLTEtraAQGPRAPALSSSWQPPANMNREPEPSCRTDT---------- 1152
Cdd:PHA03247 404 QTRPAAPVPASVPTPAPTPVPASAPPPPATPLPSAE---PGSDDGPAPPPERQPPAPATEPAPDDPDDATrkaldalrer 480
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 578817790 1153 --PAPPTHALSQ----SPAEADGSVAFVPGEAQVAREIPE 1186
Cdd:PHA03247 481 rpPEPPGADLAEllgrHPDTAGTVVRLAAREAAIAREVAE 520
|
|
| PHA03379 |
PHA03379 |
EBNA-3A; Provisional |
676-1234 |
1.25e-03 |
|
EBNA-3A; Provisional
Pssm-ID: 223066 [Multi-domain] Cd Length: 935 Bit Score: 43.51 E-value: 1.25e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 676 RVLRANTAARSCTQKEQLRQPPLPTSSpgvssgdsVARSHVQWLRHRATQSGQRRWRHALHRRLLNRRLLLAVTPWVGDV 755
Cdd:PHA03379 388 RLLLMRAGKLTERAREALEKASEPTYG--------TPRPPVEKPRPEVPQSLETATSHGSAQVPEPPPVHDLEPGPLHDQ 459
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 756 --VVPCTQASQRPAVVQTQADGLREQ--LQQARLASTPVFTLFTQLFHIDTAGCLEVvrERKALPPRLPQAGARDP-PVH 830
Cdd:PHA03379 460 hsMAPCPVAQLPPGPLQDLEPGDQLPgvVQDGRPACAPVPAPAGPIVRPWEASLSQV--PGVAFAPVMPQPMPVEPvPVP 537
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 831 LLQASSSAQSTPGHLFPNVPAQEAsksashkGSRRLAssrvERTLPqasllASTGPRPkPKTVSELLQEKRLQEARA-RE 909
Cdd:PHA03379 538 TVALERPVCPAPPLIAMQGPGETS-------GIVRVR----ERWRP-----APWTPNP-PRSPSQMSVRDRLARLRAeAQ 600
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 910 ATRGPV-VLPSQL-LVSSSVILQPPLPHTPHGRPAPGPTVLNVPLSGPGAPAAAKPGTSGSWQEAGTsakdkrlstmQAL 987
Cdd:PHA03379 601 PYQASVeVQPPQLtQVSPQQPMEYPLEPEQQMFPGSPFSQVADVMRAGGVPAMQPQYFDLPLQQPIS----------QGA 670
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 988 PLAPVFSEAEGTAPAASQAPALgpgqisvscPESGLGQSQAPAASRKQGLPEAPPFLPAAPSPTPLPVQPLSLTHIGGPH 1067
Cdd:PHA03379 671 PLAPLRASMGPVPPVPATQPQY---------FDIPLTEPINQGASAAHFLPQQPMEGPLVPERWMFQGATLSQSVRPGVA 741
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 1068 VATSVPLPVTWVLTAQGllpvpvPAVVSLPRPAgTPGP-AGLLATLLPPLTETRAAQGPRapALSSSWQPPANMNREPEP 1146
Cdd:PHA03379 742 QSQYFDLPLTQPINHGA------PAAHFLHQPP-MEGPwVPEQWMFQGAPPSQGTDVVQH--QLDALGYVLHVLNHPGVP 812
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 1147 ScrtdTPAPPTHALSQS----PAEADGSvafvpGEAQVAREIPEP-RTSSHADPPEAEPPWSGRLPafgGVIPATEPRGT 1221
Cdd:PHA03379 813 V----SPAVNQYHVSQAafglPIDEDES-----GEGSDTSEPCEAlDLSIHGRPCPQAPEWPVQGE---GGQDATEVLDL 880
|
570
....*....|...
gi 578817790 1222 pgSPSGTQEPRGP 1234
Cdd:PHA03379 881 --SIHGRPRPRTP 891
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
193-359 |
1.91e-03 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 43.03 E-value: 1.91e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 193 RKSVVSDRLQRL---LQPKLLKLEYLHQKQSKVSSELERQALEKQGREAEKEIQdiNQLPEEALLGNRLD-SHDWEKISN 268
Cdd:TIGR00618 220 RKQVLEKELKHLreaLQQTQQSHAYLTQKREAQEEQLKKQQLLKQLRARIEELR--AQEAVLEETQERINrARKAAPLAA 297
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 269 InfegSRSAEEIRKFWQNSeHPSINKQEWSReEEERLQAIAAAHGHLEWQKIAEELGTSRSafQCLQKFQQHNKALKRKE 348
Cdd:TIGR00618 298 H----IKAVTQIEQQAQRI-HTELQSKMRSR-AKLLMKRAAHVKQQSSIEEQRRLLQTLHS--QEIHIRDAHEVATSIRE 369
|
170
....*....|....*
gi 578817790 349 ----WTEEEDRMLTQ 359
Cdd:TIGR00618 370 iscqQHTLTQHIHTL 384
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
954-1234 |
3.17e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 42.14 E-value: 3.17e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 954 GPGAPAAAKPGtsgswqeagtsakdkrlstmqALPlapvfseaegtAPAASQAPALGPGQISVSCPESGlgqsQAPAASR 1033
Cdd:PRK07003 368 PGGGVPARVAG---------------------AVP-----------APGARAAAAVGASAVPAVTAVTG----AAGAALA 411
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 1034 KQGLPEAPPFLPAAPSPTPLPVQplslthiggphVATSVPLPVTWVLTAQGLLPVPVPAVVSLPRPAGTP--GPAGLLAT 1111
Cdd:PRK07003 412 PKAAAAAAATRAEAPPAAPAPPA-----------TADRGDDAADGDAPVPAKANARASADSRCDERDAQPpaDSGSASAP 480
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 1112 LLPPLTETRAAQGPRAPALSSSWQPPANMNREPEPSCRTDTPAPPTHA--LSQSPAEADGSVAFVPGEAQVAREI----- 1184
Cdd:PRK07003 481 ASDAPPDAAFEPAPRAAAPSAATPAAVPDARAPAAASREDAPAAAAPPapEARPPTPAAAAPAARAGGAAAALDVlrnag 560
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 578817790 1185 -----PEPRTSSHADPPEAEPPWSGRLPAFGGVIPATEPRGTPGSPSGTQEPRGP 1234
Cdd:PRK07003 561 mrvssDRGARAAAAAKPAAAPAAAPKPAAPRVAVQVPTPRARAATGDAPPNGAAR 615
|
|
| SANT_TRF |
cd11660 |
Telomere repeat binding factor-like DNA-binding domains of the SANT/myb-like family; Human ... |
470-499 |
4.38e-03 |
|
Telomere repeat binding factor-like DNA-binding domains of the SANT/myb-like family; Human telomere repeat binding factors, TRF1 and TRF2, function as part of the 6 component shelterin complex. TRF2 binds DNA and recruits RAP1 (via binding to the RAP1 protein c-terminal (RCT)) and TIN2 in the protection of telomeres from DNA repair machinery. Metazoan shelterin consists of 3 DNA binding proteins (TRF2, TRF1, and POT1) and 3 recruited proteins that bind to one or more of these DNA-binding proteins (RAP1, TIN2, TPP1). Schizosaccharomyces pombe TAZ1 is an orthlog and binds RAP1. Human TRF1 and TRF2 bind double-stranded DNA. hTRF2 consists of a basic N-terminus, a TRF homology domain, the RAP1 binding motif (RBM), the TIN2 binding motif (TBM) and a myb-like DNA binding domain, SANT, named after 'SWI3, ADA2, N-CoR and TFIIIB', several factors that share this domain. Tandem copies of the domain bind telomeric DNA tandem repeats as part of the capping complex. The single myb-like domain of TRF-type proteins is similar to the tandem myb_like domains found in yeast RAP1.
Pssm-ID: 212558 [Multi-domain] Cd Length: 50 Bit Score: 36.78 E-value: 4.38e-03
10 20 30
....*....|....*....|....*....|...
gi 578817790 470 KYGVGHWAKIASELP---HRSGSQCLSKWKIMM 499
Cdd:cd11660 17 KYGVGNWAKILKDYFfvnNRTSVDLKDKWRNLK 49
|
|
| PRK10263 |
PRK10263 |
DNA translocase FtsK; Provisional |
905-1232 |
7.26e-03 |
|
DNA translocase FtsK; Provisional
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 41.22 E-value: 7.26e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 905 ARAREATRGPVVLPSQLLVSSSVILQP-------PLPHTPHGRPAPGPTvlnvplSGPGAPAAAKPGTSGS--WQEagts 975
Cdd:PRK10263 330 TQSWAAPVEPVTQTPPVASVDVPPAQPtvawqpvPGPQTGEPVIAPAPE------GYPQQSQYAQPAVQYNepLQQ---- 399
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 976 akdkrlstmqalPLAPVFSEAEGTAPAASQAPALGPGQISVSCPESGLGQSQAPAASRKQGLPEAPPflPAAPSPTPLPV 1055
Cdd:PRK10263 400 ------------PVQPQQPYYAPAAEQPAQQPYYAPAPEQPAQQPYYAPAPEQPVAGNAWQAEEQQS--TFAPQSTYQTE 465
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 1056 QPlslthiggphvatsVPLPVTWVLTAQGLLPVPVPAVVSLPRPAGTPGPAGLLATLLPPLTETRAAQGPRapaLSSSWQ 1135
Cdd:PRK10263 466 QT--------------YQQPAAQEPLYQQPQPVEQQPVVEPEPVVEETKPARPPLYYFEEVEEKRAREREQ---LAAWYQ 528
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 1136 PPANMNREPEPSCRTdtpAPPTHALSQSPAEAdgsvafVPGEAQVAREIPEPRTSSHADPPEAEPPWSgrlPAFGGVipa 1215
Cdd:PRK10263 529 PIPEPVKEPEPIKSS---LKAPSVAAVPPVEA------AAAVSPLASGVKKATLATGAAATVAAPVFS---LANSGG--- 593
|
330
....*....|....*..
gi 578817790 1216 tePRGTPGSPSGTQEPR 1232
Cdd:PRK10263 594 --PRPQVKEGIGPQLPR 608
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
939-1061 |
9.20e-03 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 40.47 E-value: 9.20e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578817790 939 GRPAPGPTVLNVPLSGPGAPAAAKPGTSGSwQEAGTSAKDKRLSTMQALPLAPVFSEAEGTAPAASQAPALGPGQISVSC 1018
Cdd:PRK14951 369 AAEAAAPAEKKTPARPEAAAPAAAPVAQAA-AAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAAAPAAVAL 447
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 578817790 1019 PESGLGQSQAPAASRKQGLPEAPPFLPAAPSPTPLPVQPLSLT 1061
Cdd:PRK14951 448 APAPPAQAAPETVAIPVRVAPEPAVASAAPAPAAAPAAARLTP 490
|
|
| |
