|
Name |
Accession |
Description |
Interval |
E-value |
| TACC_C |
pfam05010 |
Transforming acidic coiled-coil-containing protein (TACC), C-terminal; This entry represents a ... |
2758-2958 |
1.96e-109 |
|
Transforming acidic coiled-coil-containing protein (TACC), C-terminal; This entry represents a C-terminal domain found in the the proteins TACC 1, 2 and 3 (TACC1-3). TACC1 is found concentrated in the centrosomes of eukaryotes which may play a conserved role in organizing centrosomal microtubules. The human TACC proteins have been linked to cancer and TACC2 has been identified as a possible tumour suppressor (AZU-1). TACC 3 from Xenopus laevis, also known as maskin, associates XMAP215 and promotes efficient microtubule elongation during mitosis. Maskin is also found to bind CPEB and elF-4E. Interestingly, the functional homolog (Alp7) in Schizosaccharomyces pombe (not included in this entry) has been shown to be required for organization of bipolar spindles.
Pssm-ID: 461517 [Multi-domain] Cd Length: 201 Bit Score: 347.05 E-value: 1.96e-109
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2758 FQQPDLDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQTVQQLVLEKEQA 2837
Cdd:pfam05010 1 YSQKDMDAALEKARNEIEEKELEINELKAKYEELRRENLEMRKIVAEFEKTIAQMIEEKQKQKELEHAEIQKVLEEKDQA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2838 LADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRGKAQQ 2917
Cdd:pfam05010 81 LADLNSVEKSFSDLFKRYEKQKEVISGYKKNEESLKKCAQDYLARIKKEEQRYQALKAHAEEKLDQANEEIAQVRSKAKA 160
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 578818737 2918 EQAAHQASLRKEQLRVDALERTLEQKNKEIEELTKICDELI 2958
Cdd:pfam05010 161 ETAALQASLRKEQMKVQSLERQLEQKTKENEELTKICDELI 201
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
24-488 |
2.19e-08 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 60.34 E-value: 2.19e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 24 PPNPEPTQRTLSAQTPRSA-QPPGNSQNIKRKQQDTPGSPdhrdASSIGSVGLGGFCTASESSASLDPCLVSPEVTEPRK 102
Cdd:PHA03247 2556 PPAAPPAAPDRSVPPPRPApRPSEPAVTSRARRPDAPPQS----ARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSP 2631
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 103 DPQGARGPEGSLLPSPPPSQEREHPSssmpfaecPPEGCLASPAAAPEDGPQTQSPRREPAPnapgdiaaafPAERDSST 182
Cdd:PHA03247 2632 SPAANEPDPHPPPTVPPPERPRDDPA--------PGRVSRPRRARRLGRAAQASSPPQRPRR----------RAARPTVG 2693
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 183 PYQEIAAVPSAGRERQPKEEGQKSSFSFSSGIDQSPGMSPVPLREPMKAPLCGEGDQPGGFESQEKEA------------ 250
Cdd:PHA03247 2694 SLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPttagppapappa 2773
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 251 --AGGFPPAESRQGVASVQVT------PEAPAAAQQGTESSAVLEKSPLKPMAPIPQDPAPRASDRERGQGEAPPQYLTD 322
Cdd:PHA03247 2774 apAAGPPRRLTRPAVASLSESreslpsPWDPADPPAAVLAPAAALPPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLG 2853
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 323 -------DLEFLRACHLPRSNSGAAPEAEVNAASQESCQQPVGAYLPHAELPWGLPSPALVPEAGGSGKEALDTIDVQGH 395
Cdd:PHA03247 2854 gsvapggDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPP 2933
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 396 PQTGMRGTKPNQVVCVAAGGQPEGGLPvSPEPSLLTPTEEAHPaSSLASFPAAQIPIAVEEPGSSSRESVSKAGMPVSAD 475
Cdd:PHA03247 2934 PPPPRPQPPLAPTTDPAGAGEPSGAVP-QPWLGALVPGRVAVP-RFRVPQPAPSREAPASSTPPLTGHSLSRVSSWASSL 3011
|
490
....*....|...
gi 578818737 476 AAKEVVDAGLVGL 488
Cdd:PHA03247 3012 ALHEETDPPPVSL 3024
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
2691-2956 |
5.84e-08 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 59.00 E-value: 5.84e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2691 AQKLQEElefaIMRIEALKLA---RQIALASRSHQDAKREAAHPTD----VSISKTALYSRigTAEVEKPAGLLFQQPDL 2763
Cdd:PTZ00121 1120 AKKKAED----ARKAEEARKAedaRKAEEARKAEDAKRVEIARKAEdarkAEEARKAEDAK--KAEAARKAEEVRKAEEL 1193
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2764 DSALQIARAEIITK---EREVSEWKdKYEESRR-----EVMEMRKIVAEYEKTIAQMIEDEQR---EKSVSHQTVQQLVL 2832
Cdd:PTZ00121 1194 RKAEDARKAEAARKaeeERKAEEAR-KAEDAKKaeavkKAEEAKKDAEEAKKAEEERNNEEIRkfeEARMAHFARRQAAI 1272
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2833 EKEQAL-AD--LNSVEKSLADLFRRYEKMKEVLEGFRKNEEvlKRCAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIA 2909
Cdd:PTZ00121 1273 KAEEARkADelKKAEEKKKADEAKKAEEKKKADEAKKKAEE--AKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKA 1350
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 578818737 2910 QVRGKaqqeqaahQASLRKEQLRVDALERTLEQKNKEIEELTKICDE 2956
Cdd:PTZ00121 1351 EAEAA--------ADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEE 1389
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
2756-2962 |
8.66e-08 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 58.15 E-value: 8.66e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2756 LLFQQPDLDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKT---IAQM-IEDEQREKSVshQTVQQLV 2831
Cdd:PRK03918 184 FIKRTENIEELIKEKEKELEEVLREINEISSELPELREELEKLEKEVKELEELkeeIEELeKELESLEGSK--RKLEEKI 261
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2832 LEKEQALADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEyLSRVKKEEQRYQALKVHAEEKLDRANA----- 2906
Cdd:PRK03918 262 RELEERIEELKKEIEELEEKVKELKELKEKAEEYIKLSEFYEEYLDE-LREIEKRLSRLEEEINGIEERIKELEEkeerl 340
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 578818737 2907 ------------EIAQVRGKAQQEQAAHQASLRKEQLR-------VDALERTLEQKNKEIEELTKICDELIAKMG 2962
Cdd:PRK03918 341 eelkkklkelekRLEELEERHELYEEAKAKKEELERLKkrltgltPEKLEKELEELEKAKEEIEEEISKITARIG 415
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
2763-2952 |
1.54e-07 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 57.37 E-value: 1.54e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2763 LDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKT---IAQMIEDEQREKsvshqtvQQLVLEKEQALA 2839
Cdd:TIGR02168 244 LQEELKEAEEELEELTAELQELEEKLEELRLEVSELEEEIEELQKElyaLANEISRLEQQK-------QILRERLANLER 316
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2840 DLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVH---AEEKLDRANAEIAQVRGKAQ 2916
Cdd:TIGR02168 317 QLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEELESRleeLEEQLETLRSKVAQLELQIA 396
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 578818737 2917 qeqaahqaSLRKEQLRVDA----LERTLEQKNKEIEELTK 2952
Cdd:TIGR02168 397 --------SLNNEIERLEArlerLEDRRERLQQEIEELLK 428
|
|
| PTZ00449 |
PTZ00449 |
104 kDa microneme/rhoptry antigen; Provisional |
2185-2485 |
3.47e-07 |
|
104 kDa microneme/rhoptry antigen; Provisional
Pssm-ID: 185628 [Multi-domain] Cd Length: 943 Bit Score: 56.24 E-value: 3.47e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2185 SGENLASETKTESAKTEGPSpalleETPLEPAVGPKAacPLDSESAEGVVPPASGggrvQNSPPVGRKtlPLTTapEAGE 2264
Cdd:PTZ00449 492 SKKKLAPIEEEDSDKHDEPP-----EGPEASGLPPKA--PGDKEGEEGEHEDSKE----SDEPKEGGK--PGET--KEGE 556
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2265 VTPSDSGGQEDSPAK--GLSVRLEFDySEDKSSWDNQQENPPPTKKIGKKPVAKMPLRRPKMKKTPeKLDNTPASP--PR 2340
Cdd:PTZ00449 557 VGKKPGPAKEHKPSKipTLSKKPEFP-KDPKHPKDPEEPKKPKRPRSAQRPTRPKSPKLPELLDIP-KSPKRPESPksPK 634
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2341 SPAEPNDiPIAKgtytfdidkwDDPNFNPFSSTSKMQESPKLPqqsynFDPDTCDESVDPFKTSSKTPSSPSKSPASFEI 2420
Cdd:PTZ00449 635 RPPPPQR-PSSP----------ERPEGPKIIKSPKPPKSPKPP-----FDPKFKEKFYDDYLDAAAKSKETKTTVVLDES 698
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 578818737 2421 PASAMEANGVDGDGLNKPAKKKKTPLKTVKKSPKRSPLSDPPSQDPTPAATPETPPVISAVVHAT 2485
Cdd:PTZ00449 699 FESILKETLPETPGTPFTTPRPLPPKLPRDEEFPFEPIGDPDAEQPDDIEFFTPPEEERTFFHET 763
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
2683-2959 |
3.73e-07 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 56.10 E-value: 3.73e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2683 AEKnpplfAQKLQEELEfaimRIEALKLARQIALASRSHQDAKREAAhptdvsisktalysrigtaevekpagllfqqpD 2762
Cdd:COG1196 212 AER-----YRELKEELK----ELEAELLLLKLRELEAELEELEAELE--------------------------------E 250
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2763 LDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIEDEQREKsvshQTVQQLVLEKEQALADLN 2842
Cdd:COG1196 251 LEAELEELEAELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLE----ERRRELEERLEELEEELA 326
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2843 SVEKSLADLfrrYEKMKEVLEGFRKNEEVLKRCAQEyLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRGKAQQEQAAH 2922
Cdd:COG1196 327 ELEEELEEL---EEELEELEEELEEAEEELEEAEAE-LAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQL 402
|
250 260 270
....*....|....*....|....*....|....*..
gi 578818737 2923 QASLRKEQLRVDALERTLEQKNKEIEELTKICDELIA 2959
Cdd:COG1196 403 EELEEAEEALLERLERLEEELEELEEALAELEEEEEE 439
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
2763-2961 |
4.59e-07 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 55.54 E-value: 4.59e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2763 LDSALQIARAEIITKE-REVSEWKDKYEESRREVMEMRKIVAEYEKTIAQmiedeqreksvshqtvqqlVLEKEQALADL 2841
Cdd:COG4717 47 LLERLEKEADELFKPQgRKPELNLKELKELEEELKEAEEKEEEYAELQEE-------------------LEELEEELEEL 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2842 NSVEKSLADLFRRYEKMKEVLEGFRKNEEvLKRCAQEYLSRVKKEEQRYQALKvHAEEKLDRANAEIAQVRGKAQQEQAA 2921
Cdd:COG4717 108 EAELEELREELEKLEKLLQLLPLYQELEA-LEAELAELPERLEELEERLEELR-ELEEELEELEAELAELQEELEELLEQ 185
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 578818737 2922 HQASLRKE-----------QLRVDALERTLEQKNKEIEELTKICDELIAKM 2961
Cdd:COG4717 186 LSLATEEElqdlaeeleelQQRLAELEEELEEAQEELEELEEELEQLENEL 236
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
2691-2960 |
7.82e-07 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 55.15 E-value: 7.82e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2691 AQKLQEELEFAIMRIEALKLARQI---ALASRSHQDAKREAAHPTDVSISKTALYSRigTAEVEKPAGLLFQQPDLDSAL 2767
Cdd:PTZ00121 1472 ADEAKKKAEEAKKADEAKKKAEEAkkkADEAKKAAEAKKKADEAKKAEEAKKADEAK--KAEEAKKADEAKKAEEKKKAD 1549
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2768 QIARAEIITKEREVSewkdKYEESRREvmEMRKIVAEYEKTIAQMIEdEQREKSVSHQTVQQLVLEKEQALADlnSVEKS 2847
Cdd:PTZ00121 1550 ELKKAEELKKAEEKK----KAEEAKKA--EEDKNMALRKAEEAKKAE-EARIEEVMKLYEEEKKMKAEEAKKA--EEAKI 1620
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2848 LADLFRRYEKMKEVLEGFRKNEEVLKRCAQEylsrVKKEEQRYqalKVHAEEKLDRANAEiaqvRGKAQQEQAAHQASLR 2927
Cdd:PTZ00121 1621 KAEELKKAEEEKKKVEQLKKKEAEEKKKAEE----LKKAEEEN---KIKAAEEAKKAEED----KKKAEEAKKAEEDEKK 1689
|
250 260 270
....*....|....*....|....*....|...
gi 578818737 2928 KEQlrvdALERTLEQKNKeIEELTKICDELIAK 2960
Cdd:PTZ00121 1690 AAE----ALKKEAEEAKK-AEELKKKEAEEKKK 1717
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
2702-2952 |
2.12e-06 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 53.99 E-value: 2.12e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2702 IMRIEALKLARQIALASRSHQDAKREAAHPTDVSISKTALYSRIgtAEVEKpaglLFQQPDLDSALQIARAEiitKEREV 2781
Cdd:PTZ00121 1551 LKKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARI--EEVMK----LYEEEKKMKAEEAKKAE---EAKIK 1621
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2782 SEWKDKYEESRREVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQTVQQLVLEKEQA--LADLNSVEKSLADLFRRYEKMK 2859
Cdd:PTZ00121 1622 AEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAeeAKKAEEDEKKAAEALKKEAEEA 1701
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2860 EVLEGFRKNEEVLKRCAQEYlsRVKKEEQRYQALKVHAEEKLDRANAEIAQVR-------GKAQQEQAAHQASLRKEQLR 2932
Cdd:PTZ00121 1702 KKAEELKKKEAEEKKKAEEL--KKAEEENKIKAEEAKKEAEEDKKKAEEAKKDeeekkkiAHLKKEEEKKAEEIRKEKEA 1779
|
250 260
....*....|....*....|..
gi 578818737 2933 V--DALERTLEQKNKEIEELTK 2952
Cdd:PTZ00121 1780 VieEELDEEDEKRRMEVDKKIK 1801
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
2771-2950 |
2.70e-06 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 53.52 E-value: 2.70e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2771 RAEIITKEREVseWKDKYEESRREVMEMRKIVAEYEktiaQMIEDEQREKSVSHQTVQQLVL---EKEQALADLNSVEKS 2847
Cdd:TIGR02168 219 KAELRELELAL--LVLRLEELREELEELQEELKEAE----EELEELTAELQELEEKLEELRLevsELEEEIEELQKELYA 292
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2848 LADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRGKaqqeqaahqasLR 2927
Cdd:TIGR02168 293 LANEISRLEQQKQILRERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAE-----------LE 361
|
170 180
....*....|....*....|...
gi 578818737 2928 KEQLRVDALERTLEQKNKEIEEL 2950
Cdd:TIGR02168 362 ELEAELEELESRLEELEEQLETL 384
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
2692-2960 |
3.18e-06 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 53.02 E-value: 3.18e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2692 QKLQEELEFAIMRIEALKLARQIALASRSHQDAKREAAhptdvsisKTALYSRigTAEVEkpagllfqqpDLDSALQIAR 2771
Cdd:COG1196 235 RELEAELEELEAELEELEAELEELEAELAELEAELEEL--------RLELEEL--ELELE----------EAQAEEYELL 294
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2772 AEIITKEREVSEWKdkyEESRREVMEMRKIVAEYEKTIAQMIEDEQREKSVShQTVQQLVLEKEQALADLNSVEKSLADL 2851
Cdd:COG1196 295 AELARLEQDIARLE---ERRRELEERLEELEEELAELEEELEELEEELEELE-EELEEAEEELEEAEAELAEAEEALLEA 370
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2852 FRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRG--KAQQEQAAHQASLRKE 2929
Cdd:COG1196 371 EAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAEleEEEEEEEEALEEAAEE 450
|
250 260 270
....*....|....*....|....*....|.
gi 578818737 2930 QLRVDALERTLEQKNKEIEELTKICDELIAK 2960
Cdd:COG1196 451 EAELEEEEEALLELLAELLEEAALLEAALAE 481
|
|
| COG1340 |
COG1340 |
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]; |
2771-2960 |
3.28e-06 |
|
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
Pssm-ID: 440951 [Multi-domain] Cd Length: 297 Bit Score: 51.84 E-value: 3.28e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2771 RAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMiEDEQreksvshQTvQQLVLEKEQALadlnsVEKsLAD 2850
Cdd:COG1340 80 RDELNEKLNELREELDELRKELAELNKAGGSIDKLRKEIERL-EWRQ-------QT-EVLSPEEEKEL-----VEK-IKE 144
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2851 LFRRYEKMKEVLEGFRKNEEVLKRCAQEylsRVKKEEQRyQALKVHAEEkLDRANAEIAQVRGKAQqeqaahqaSLRKE- 2929
Cdd:COG1340 145 LEKELEKAKKALEKNEKLKELRAELKEL---RKEAEEIH-KKIKELAEE-AQELHEEMIELYKEAD--------ELRKEa 211
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 578818737 2930 ----------QLRVDALERTLEQKNKEIEELTKICDELIAK 2960
Cdd:COG1340 212 delhkeiveaQEKADELHEEIIELQKELRELRKELKKLRKK 252
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
2691-2943 |
3.75e-06 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 52.75 E-value: 3.75e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2691 AQKLQE--------ELEFAIMRIEALK-----LARQIALASRSHQDAKREAAHpTDVSISKT------------------ 2739
Cdd:TIGR02168 212 AERYKElkaelrelELALLVLRLEELReeleeLQEELKEAEEELEELTAELQE-LEEKLEELrlevseleeeieelqkel 290
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2740 -ALYSRIGTAEV------EKPAGLLFQQPDLDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQM 2812
Cdd:TIGR02168 291 yALANEISRLEQqkqilrERLANLERQLEELEAQLEELESKLDELAEELAELEEKLEELKEELESLEAELEELEAELEEL 370
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2813 iEDEQREKSVSHQTVQQLVLEKEQALADLNS----VEKSLADLFRRYEKMKEVLEGFRKN-EEVLKRCAQEYLSRVKKEE 2887
Cdd:TIGR02168 371 -ESRLEELEEQLETLRSKVAQLELQIASLNNeierLEARLERLEDRRERLQQEIEELLKKlEEAELKELQAELEELEEEL 449
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*.
gi 578818737 2888 QRYQALKVHAEEKLDRANAEIAQVRgkaqQEQAAHQASLRKEQLRVDALERTLEQK 2943
Cdd:TIGR02168 450 EELQEELERLEEALEELREELEEAE----QALDAAERELAQLQARLDSLERLQENL 501
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
2694-2912 |
5.86e-06 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 52.38 E-value: 5.86e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2694 LQEELEFAIMRIEALKlaRQIALASRSHQDAKREAAHpTDVSISKT-----ALYSRIGTAEVEKPAgllfqqpdLDSALQ 2768
Cdd:TIGR02169 292 VKEKIGELEAEIASLE--RSIAEKERELEDAEERLAK-LEAEIDKLlaeieELEREIEEERKRRDK--------LTEEYA 360
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2769 IARAEIITKEREVSEWKDKYEESRREVMEMRKivaEYEKTIAQMiEDEQREKSVSHQTVQQLVLEKEQALADLNSVEKSL 2848
Cdd:TIGR02169 361 ELKEELEDLRAELEEVDKEFAETRDELKDYRE---KLEKLKREI-NELKRELDRLQEELQRLSEELADLNAAIAGIEAKI 436
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 578818737 2849 ADLfrrYEKMKEVLEGFRKNEEVLKRCAQEylsrVKKEEQRYQALKvhaeEKLDRANAEIAQVR 2912
Cdd:TIGR02169 437 NEL---EEEKEDKALEIKKQEWKLEQLAAD----LSKYEQELYDLK----EEYDRVEKELSKLQ 489
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
2771-2952 |
5.97e-06 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 52.37 E-value: 5.97e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2771 RAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQM---IEDEQREKSVSHQTVQQLVLEKEQALADLNSVEKS 2847
Cdd:TIGR02168 676 RREIEELEEKIEELEEKIAELEKALAELRKELEELEEELEQLrkeLEELSRQISALRKDLARLEAEVEQLEERIAQLSKE 755
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2848 LADLfrrYEKMKEVLEGFRKNEEVLKRCAQEyLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRGKAQQEQAAHQASLR 2927
Cdd:TIGR02168 756 LTEL---EAEIEELEERLEEAEEELAEAEAE-IEELEAQIEQLKEELKALREALDELRAELTLLNEEAANLRERLESLER 831
|
170 180
....*....|....*....|....*...
gi 578818737 2928 K---EQLRVDALERTLEQKNKEIEELTK 2952
Cdd:TIGR02168 832 RiaaTERRLEDLEEQIEELSEDIESLAA 859
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
2770-2959 |
7.23e-06 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 51.99 E-value: 7.23e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2770 ARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIED-----EQREKSVSHQTVQQ---------LVLEKE 2835
Cdd:TIGR02169 154 ERRKIIDEIAGVAEFDRKKEKALEELEEVEENIERLDLIIDEKRQQlerlrREREKAERYQALLKekreyegyeLLKEKE 233
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2836 QALADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKE-EQRYQALKvhaeEKLDRANAEIAQVRGK 2914
Cdd:TIGR02169 234 ALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLgEEEQLRVK----EKIGELEAEIASLERS 309
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 578818737 2915 AQQEQAAHQAS---LRKEQLRVDALERTLEQKNKEIEELTKICDELIA 2959
Cdd:TIGR02169 310 IAEKERELEDAeerLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTE 357
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
2756-2958 |
9.71e-06 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 51.61 E-value: 9.71e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2756 LLFQQPDLDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIEDEQ-------REKSVSHQTVQ 2828
Cdd:TIGR02169 228 LLKEKEALERQKEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGEEEQlrvkekiGELEAEIASLE 307
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2829 QLVLEKEQALADLnsvEKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVHAEEkLDRANAEi 2908
Cdd:TIGR02169 308 RSIAEKERELEDA---EERLAKLEAEIDKLLAEIEELEREIEEERKRRDKLTEEYAELKEELEDLRAELEE-VDKEFAE- 382
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 578818737 2909 aqvrgkaqqeqaahqasLRKEQlrvDALERTLEQKNKEIEELTKICDELI 2958
Cdd:TIGR02169 383 -----------------TRDEL---KDYREKLEKLKREINELKRELDRLQ 412
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
2749-2957 |
1.28e-05 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 51.22 E-value: 1.28e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2749 EVEKPAGLLFQQPdldSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQTVQ 2828
Cdd:PRK03918 311 EIEKRLSRLEEEI---NGIEERIKELEEKEERLEELKKKLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPE 387
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2829 QLVLE-------KEQALADLNSVEKSLADLFRRYEKMKEVLEGFRK------------NEEVLKRCAQEYLSRVKKEEQR 2889
Cdd:PRK03918 388 KLEKEleelekaKEEIEEEISKITARIGELKKEIKELKKAIEELKKakgkcpvcgrelTEEHRKELLEEYTAELKRIEKE 467
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 578818737 2890 YQALKvHAEEKLDRANAEIAQVRGKAQQ--EQAAHQASLR--KEQLRVDALERtLEQKNKEIEELTKICDEL 2957
Cdd:PRK03918 468 LKEIE-EKERKLRKELRELEKVLKKESEliKLKELAEQLKelEEKLKKYNLEE-LEKKAEEYEKLKEKLIKL 537
|
|
| EnvC |
COG4942 |
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ... |
2759-2960 |
1.29e-05 |
|
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 443969 [Multi-domain] Cd Length: 377 Bit Score: 50.15 E-value: 1.29e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2759 QQPDLDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIaqmiedEQREKSVSHQTVQQLVLEKEQAL 2838
Cdd:COG4942 49 EEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAEL------EAQKEELAELLRALYRLGRQPPL 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2839 ADLNSVEkSLADLFRRYEKMKEVLEGFRKNEEVLKRcAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRGKAQQE 2918
Cdd:COG4942 123 ALLLSPE-DFLDAVRRLQYLKYLAPARREQAEELRA-DLAELAALRAELEAERAELEALLAELEEERAALEALKAERQKL 200
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 578818737 2919 qaahqasLRKEQLRVDALERTLEQKNKEIEELTKICDELIAK 2960
Cdd:COG4942 201 -------LARLEKELAELAAELAELQQEAEELEALIARLEAE 235
|
|
| DUF5401 |
pfam17380 |
Family of unknown function (DUF5401); This is a family of unknown function found in ... |
2437-2949 |
2.03e-05 |
|
Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.
Pssm-ID: 375164 [Multi-domain] Cd Length: 722 Bit Score: 50.12 E-value: 2.03e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2437 KPAKKKKTPlKTVKKSPKRSPLSDPPSQDPTPAATPETPP---VISAVVHATDEEKlAVTNQKWTCMTvdleadkqdypq 2513
Cdd:pfam17380 62 KPMRKYETA-KTIITTPAPIPSSYPVSAEVSPPGAPAAAPeefVFSTIRPKSRKPK-ARTRGKKRKTT------------ 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2514 pSDLSTFVNETKFSSPTEELDYRNSYEIEYMEKIGSSLPQDDDAPKKQALYLMFDTSQESPVKSSPVRM-SESPTPCS-G 2591
Cdd:pfam17380 128 -TTMIQTTTPMMVTTSSSALEMTTTPKIVIFASKKNASGGNRSGEQRKQIQLIRRRRGNHSAFTRPGRPrTTTPMPVThA 206
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2592 SSFEETEALVNTAAKNQHPVPRGLAPNQESHLQvpeKSSQKELEAMGLGTPSEAIEITapeGSFASADALLSRLAHPVSL 2671
Cdd:pfam17380 207 TRFVPGIQMSTVAPKEVQGMPHTLAPYEKMERR---KESFNLAEDVTTMTPEYTVRYN---GQTMTENEFLNQLLHIVQH 280
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2672 CGALDylEPDLAEKNPPLFAQKLQEELEFAIMRIEAlklARQIALASRSHQDA-KREA---AHPTDVSISKTALYSRIGT 2747
Cdd:pfam17380 281 QKAVS--ERQQQEKFEKMEQERLRQEKEEKAREVER---RRKLEEAEKARQAEmDRQAaiyAEQERMAMERERELERIRQ 355
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2748 AEVEKPAGLLFQQpdlDSALQIARAEIItkEREVSEWKDKYEESRREVMEMRKivaeyektiaQMIEDEQREKSVSHQTV 2827
Cdd:pfam17380 356 EERKRELERIRQE---EIAMEISRMREL--ERLQMERQQKNERVRQELEAARK----------VKILEEERQRKIQQQKV 420
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2828 QQLVLEKEQaladlnsvEKSLADLFRRYEKMKEvLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVHAEEKlDRANAE 2907
Cdd:pfam17380 421 EMEQIRAEQ--------EEARQREVRRLEEERA-REMERVRLEEQERQQQVERLRQQEEERKRKKLELEKEKR-DRKRAE 490
|
490 500 510 520
....*....|....*....|....*....|....*....|..
gi 578818737 2908 iAQVRGKAQQEQAAHQASLRKEQLRVDALERTLEQKNKEIEE 2949
Cdd:pfam17380 491 -EQRRKILEKELEERKQAMIEEERKRKLLEKEMEERQKAIYE 531
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
2771-2959 |
2.43e-05 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 50.06 E-value: 2.43e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2771 RAEIITKEREVSEWKDKYEESRREVMEMRKIVAE------YEKTIAQMIEDEQREKSVSHQTV----------------- 2827
Cdd:PRK03918 458 TAELKRIEKELKEIEEKERKLRKELRELEKVLKKeselikLKELAEQLKELEEKLKKYNLEELekkaeeyeklkeklikl 537
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2828 --QQLVLEKEqaLADLNSVEKSLADLFRRYEKMKEVL---------EGFRKNEEV------LKRCAQEYL------SRVK 2884
Cdd:PRK03918 538 kgEIKSLKKE--LEKLEELKKKLAELEKKLDELEEELaellkeleeLGFESVEELeerlkeLEPFYNEYLelkdaeKELE 615
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2885 KEEQRYQALK---VHAEEKLDRANAEIAQVRGK----AQQEQAAHQASLRKEQLRvdaLERTLEQKNKEIEELTKICDEL 2957
Cdd:PRK03918 616 REEKELKKLEeelDKAFEELAETEKRLEELRKEleelEKKYSEEEYEELREEYLE---LSRELAGLRAELEELEKRREEI 692
|
..
gi 578818737 2958 IA 2959
Cdd:PRK03918 693 KK 694
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
107-688 |
3.36e-05 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 49.94 E-value: 3.36e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 107 ARGPEGSLLPSPPPSQerehPSSSMPFAEC---PPEGCLASPAAAPEDGPQTQSPRrepapnAPGDIAAAFPAerdsstP 183
Cdd:PHA03247 2548 AGDPPPPLPPAAPPAA----PDRSVPPPRPaprPSEPAVTSRARRPDAPPQSARPR------APVDDRGDPRG------P 2611
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 184 YQEIAAVPSAGRERQPKEEGQKSSFSFSSGidqSPGMSPVPLRePMKAPLCGEGDQPGGFESQEKEAAGGFPPAESRQGV 263
Cdd:PHA03247 2612 APPSPLPPDTHAPDPPPPSPSPAANEPDPH---PPPTVPPPER-PRDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRA 2687
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 264 ASVQVTPEAPAAAQQGTESSAVLEKSPLKPMAPIPQDPAP-RASDRERGQGEAPPqyltddleflrachlPRSNSGAAPE 342
Cdd:PHA03247 2688 ARPTVGSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAaRQASPALPAAPAPP---------------AVPAGPATPG 2752
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 343 AEVNAASQESCQQPVGAYLPHAelPWGLPSPALVPEAGGSGKEALDTIDVQGHPqtgmrgTKPNQVVCVAAGGQPEGGLP 422
Cdd:PHA03247 2753 GPARPARPPTTAGPPAPAPPAA--PAAGPPRRLTRPAVASLSESRESLPSPWDP------ADPPAAVLAPAAALPPAASP 2824
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 423 VSPEPSLLTPTEEAHPASSLASFPAAQIPIAVEEPGSSSRESVSKAGMPVSADAAKEVVDaglvglerqvsdlgskgehp 502
Cdd:PHA03247 2825 AGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPARPPVR-------------------- 2884
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 503 egdpgEVPAPSPQERGEHLNTEQSHEVQPGVPPPPLPKEQSHEVQPGAPPPPLPKAPSESARGPPGPTDGAKVHEDSTSP 582
Cdd:PHA03247 2885 -----RLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAV 2959
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 583 AVAKEGSRSPGD---------SPGGKEEAPEPP-----DGGDPGNLQGEDSQAFSSKRDP-EVGKDELSKPSSDAESRDH 647
Cdd:PHA03247 2960 PQPWLGALVPGRvavprfrvpQPAPSREAPASStppltGHSLSRVSSWASSLALHEETDPpPVSLKQTLWPPDDTEDSDA 3039
|
570 580 590 600
....*....|....*....|....*....|....*....|....
gi 578818737 648 PSSHSAQPPRKGGAG---HTDGPHSQTAEADASGLPHKLGEEDP 688
Cdd:PHA03247 3040 DSLFDSDSERSDLEAldpLPPEPHDPFAHEPDPATPEAGARESP 3083
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
2767-2908 |
3.88e-05 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 49.29 E-value: 3.88e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2767 LQIARAEIITKEREVSEWKDKYEESRREVMEMRKI--VAEYEKtiaqmIEDEQREKSVSHQTVQQlvlEKEQALADLNSV 2844
Cdd:PRK03918 621 LKKLEEELDKAFEELAETEKRLEELRKELEELEKKysEEEYEE-----LREEYLELSRELAGLRA---ELEELEKRREEI 692
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 578818737 2845 EKSLADLFRRYEKMKEVlegfRKNEEVLKRcAQEYLSRVKKEEQRYQAL-KVHAEEKLDRANAEI 2908
Cdd:PRK03918 693 KKTLEKLKEELEEREKA----KKELEKLEK-ALERVEELREKVKKYKALlKERALSKVGEIASEI 752
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
2681-2884 |
4.24e-05 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 49.30 E-value: 4.24e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2681 DLAEKNPPLFAQKLQEELEFAIMRIEALKLARQIALASRSHQDAKREAAHPTDvsiSKTALYSRIGTAEvEKPAGLLFQQ 2760
Cdd:TIGR02169 361 ELKEELEDLRAELEEVDKEFAETRDELKDYREKLEKLKREINELKRELDRLQE---ELQRLSEELADLN-AAIAGIEAKI 436
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2761 PDLDSALQIARAEIITKEREVSEWKDKYEESRRevmEMRKIVAEYEKtiaqmIEDEQREKS-----------VSHQTV-- 2827
Cdd:TIGR02169 437 NELEEEKEDKALEIKKQEWKLEQLAADLSKYEQ---ELYDLKEEYDR-----VEKELSKLQrelaeaeaqarASEERVrg 508
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 578818737 2828 ---QQLVLEkeqalADLNSVEKSLADLFR---RYEKMKEVLEGFR------KNEEVLKRCAqEYLSRVK 2884
Cdd:TIGR02169 509 graVEEVLK-----ASIQGVHGTVAQLGSvgeRYATAIEVAAGNRlnnvvvEDDAVAKEAI-ELLKRRK 571
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
2789-2952 |
4.46e-05 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 48.75 E-value: 4.46e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2789 EESRREVMEMRKIVAEYEKTIAQmIEDEQREKSVSHQTVQQLVLEKEQALADLNSVEKSLADLFRRYEKMKEVLEGFRKN 2868
Cdd:COG4372 31 EQLRKALFELDKLQEELEQLREE-LEQAREELEQLEEELEQARSELEQLEEELEELNEQLQAAQAELAQAQEELESLQEE 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2869 EEVLkrcaQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQvrgkaqqeqaahqaslRKEQLRvdALERTLEQKNKEIE 2948
Cdd:COG4372 110 AEEL----QEELEELQKERQDLEQQRKQLEAQIAELQSEIAE----------------REEELK--ELEEQLESLQEELA 167
|
....
gi 578818737 2949 ELTK 2952
Cdd:COG4372 168 ALEQ 171
|
|
| COG1340 |
COG1340 |
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]; |
2771-2963 |
4.92e-05 |
|
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
Pssm-ID: 440951 [Multi-domain] Cd Length: 297 Bit Score: 47.98 E-value: 4.92e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2771 RAEIITkerEVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIE------DEQREKSVSHQTVQQLVLEKEQALADLNSV 2844
Cdd:COG1340 31 RDELNE---ELKELAEKRDELNAQVKELREEAQELREKRDELNEkvkelkEERDELNEKLNELREELDELRKELAELNKA 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2845 EKSLADLFRRYEKMK-----EVLeGFRKNEEVLKRCAQ--EYLSRVKKEEQ----------RYQALKVHAE--------- 2898
Cdd:COG1340 108 GGSIDKLRKEIERLEwrqqtEVL-SPEEEKELVEKIKEleKELEKAKKALEkneklkelraELKELRKEAEeihkkikel 186
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 578818737 2899 -EKLDRANAEIAQVRGKaqqeqaahQASLRKEqlrVDALERTLEQKNKEIEELTKICDELIAKMGK 2963
Cdd:COG1340 187 aEEAQELHEEMIELYKE--------ADELRKE---ADELHKEIVEAQEKADELHEEIIELQKELRE 241
|
|
| HEC1 |
COG5185 |
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ... |
2692-2952 |
5.21e-05 |
|
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 444066 [Multi-domain] Cd Length: 594 Bit Score: 48.80 E-value: 5.21e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2692 QKLQEELEFAIMRIEALKLARQIALA--SRSHQDAKREaahpTDVSIsktalysRIGTAEVEKpagllfQQPDLDSALQI 2769
Cdd:COG5185 296 EKIAEYTKSIDIKKATESLEEQLAAAeaEQELEESKRE----TETGI-------QNLTAEIEQ------GQESLTENLEA 358
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2770 ARAEII---------TKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIED---EQREKSVSHQT-VQQLVLEKEQ 2836
Cdd:COG5185 359 IKEEIEnivgevelsKSSEELDSFKDTIESTKESLDEIPQNQRGYAQEILATLEDtlkAADRQIEELQRqIEQATSSNEE 438
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2837 ALADLNSVEKSLADLFRR---------YEKMKEVLEGFRKNEEVLKRcaqeylsRVKKEEQRYQALKVHAEEKLDRANAE 2907
Cdd:COG5185 439 VSKLLNELISELNKVMREadeesqsrlEEAYDEINRSVRSKKEDLNE-------ELTQIESRVSTLKATLEKLRAKLERQ 511
|
250 260 270 280
....*....|....*....|....*....|....*....|....*
gi 578818737 2908 IAQVRGKAQQEQAAHQASLRKEQLRVDALERTLEQKNKEIEELTK 2952
Cdd:COG5185 512 LEGVRSKLDQVAESLKDFMRARGYAHILALENLIPASELIQASNA 556
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
2757-2949 |
8.57e-05 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 47.59 E-value: 8.57e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2757 LFQQPDLDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEyektIAQMIEDEQREKSVSHQTVQQLVLEKEQ 2836
Cdd:COG4372 37 LFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELEE----LNEQLQAAQAELAQAQEELESLQEEAEE 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2837 ALADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQAL-KVHAEEKLDRANAEIAQV---- 2911
Cdd:COG4372 113 LQEELEELQKERQDLEQQRKQLEAQIAELQSEIAEREEELKELEEQLESLQEELAALeQELQALSEAEAEQALDELlkea 192
|
170 180 190
....*....|....*....|....*....|....*....
gi 578818737 2912 -RGKAQQEQAAHQASLRKEQLRVDALERTLEQKNKEIEE 2949
Cdd:COG4372 193 nRNAEKEEELAEAEKLIESLPRELAEELLEAKDSLEAKL 231
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
2766-2950 |
8.90e-05 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 48.37 E-value: 8.90e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2766 ALQIARAEIITKEREVSEWKDKYEESRREVMEMRKI----------------VAEYEKTIAQmIEDEQREKSVSHQTVQQ 2829
Cdd:COG4913 611 KLAALEAELAELEEELAEAEERLEALEAELDALQERrealqrlaeyswdeidVASAEREIAE-LEAELERLDASSDDLAA 689
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2830 LVLEKEQALADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKRcAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIA 2909
Cdd:COG4913 690 LEEQLEELEAELEELEEELDELKGEIGRLEKELEQAEEELDELQD-RLEAAEDLARLELRALLEERFAAALGDAVERELR 768
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 578818737 2910 QvrgkaqqeqaahqaSLRKeqlRVDALERTLEQKNKEIEEL 2950
Cdd:COG4913 769 E--------------NLEE---RIDALRARLNRAEEELERA 792
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
2704-2960 |
1.45e-04 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 47.83 E-value: 1.45e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2704 RIEALKLARQialASRSHQDAKR--------EAAHPTDVSISKTALYSRIGTAEVEKPAGLLFQQPDLDSALQIARAEII 2775
Cdd:PTZ00121 1225 KAEAVKKAEE---AKKDAEEAKKaeeernneEIRKFEEARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEEK 1301
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2776 TKEREV---SEWKDKYEESRREVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQTVQQLVLEKEQALAD--LNSVEKSLAD 2850
Cdd:PTZ00121 1302 KKADEAkkkAEEAKKADEAKKKAEEAKKKADAAKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKAEAAekKKEEAKKKAD 1381
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2851 LFRRYEKMKEVLEGFRKNEEVLKRCAQEyLSRVKKEEQRYQALKVHAEE--KLDRANAEIAQVRgKAQQEQAAHQASLRK 2928
Cdd:PTZ00121 1382 AAKKKAEEKKKADEAKKKAEEDKKKADE-LKKAAAAKKKADEAKKKAEEkkKADEAKKKAEEAK-KADEAKKKAEEAKKA 1459
|
250 260 270
....*....|....*....|....*....|...
gi 578818737 2929 EQLRVDALE-RTLEQKNKEIEELTKiCDELIAK 2960
Cdd:PTZ00121 1460 EEAKKKAEEaKKADEAKKKAEEAKK-ADEAKKK 1491
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
2768-2942 |
1.87e-04 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 47.07 E-value: 1.87e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2768 QIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQ-TVQQLVLEKEQALADLNSVEK 2846
Cdd:COG4717 67 ELNLKELKELEEELKEAEEKEEEYAELQEELEELEEELEELEAELEELREELEKLEKLlQLLPLYQELEALEAELAELPE 146
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2847 SLADLFRRYEKMKEVLEGFRKNEEVLKRCAQE--------------YLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVR 2912
Cdd:COG4717 147 RLEELEERLEELRELEEELEELEAELAELQEEleelleqlslateeELQDLAEELEELQQRLAELEEELEEAQEELEELE 226
|
170 180 190
....*....|....*....|....*....|
gi 578818737 2913 GKAQQEqaahqaslrKEQLRVDALERTLEQ 2942
Cdd:COG4717 227 EELEQL---------ENELEAAALEERLKE 247
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
93-495 |
1.89e-04 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 47.29 E-value: 1.89e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 93 VSPEVTEPRKDPQGARGPEGSLLPSP----PPSQEREHPSSSMPFAECPPEGCLASPAAAPEDGPQTQSPRREPAPNAPG 168
Cdd:PRK07764 387 VAGGAGAPAAAAPSAAAAAPAAAPAPaaaaPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQP 466
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 169 DIAAAFPAERDSSTPYQEIAAVPSAGRERQPKEEGQKSSFSFSSGIDQS--PGMSPVPLREPMKAPLCGEGDQPGGFESQ 246
Cdd:PRK07764 467 APAPAAAPEPTAAPAPAPPAAPAPAAAPAAPAAPAAPAGADDAATLRERwpEILAAVPKRSRKTWAILLPEATVLGVRGD 546
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 247 E---KEAAGGFPPAESRQGVASV-----------QVTPEA-----PAAAQQGTESSAVLEKSPLKPMAPIPQDPAPRASD 307
Cdd:PRK07764 547 TlvlGFSTGGLARRFASPGNAEVlvtalaeelggDWQVEAvvgpaPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAA 626
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 308 RERGQGEAPPQYLTDDleflRACHLPRSNSGAAPEAEVNAASQESCQQPVGAYLPHAELPWGLPSPALVPEAGGSGKEAL 387
Cdd:PRK07764 627 PAPAGAAAAPAEASAA----PAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPA 702
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 388 DTIDVQGHPQTGMRGTKPNQVVCVAAGGQPEGGLPVSPEPSllTPTEEAHPASSLASFPAAQIPIAVEEPGSSSRESVSK 467
Cdd:PRK07764 703 PAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPP--EPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPS 780
|
410 420
....*....|....*....|....*...
gi 578818737 468 AGMPVSADAAKEVVDAGLVGLERQVSDL 495
Cdd:PRK07764 781 EEEEMAEDDAPSMDDEDRRDAEEVAMEL 808
|
|
| TPH |
pfam13868 |
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ... |
2768-2960 |
3.42e-04 |
|
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.
Pssm-ID: 464007 [Multi-domain] Cd Length: 341 Bit Score: 45.68 E-value: 3.42e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2768 QIARAEIITKEREvsewkdkyEESRREVMEMRKivaEYEKTIAQMIEDEQREKSVSHQTVQQLV-----------LEKEQ 2836
Cdd:pfam13868 27 QIAEKKRIKAEEK--------EEERRLDEMMEE---ERERALEEEEEKEEERKEERKRYRQELEeqieereqkrqEEYEE 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2837 ALADLNSV--------EKSLADLFRRYEKMKEVLEGFRK-NEEVLKRCAQEYLsRVKKEEQRYQAlkvHAEEKLDRANAE 2907
Cdd:pfam13868 96 KLQEREQMdeiveriqEEDQAEAEEKLEKQRQLREEIDEfNEEQAEWKELEKE-EEREEDERILE---YLKEKAEREEER 171
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 578818737 2908 IAQVRGKAqqeqaahqaslRKEQLRVDALERTLEQKNKEIEELtkicDELIAK 2960
Cdd:pfam13868 172 EAEREEIE-----------EEKEREIARLRAQQEKAQDEKAER----DELRAK 209
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
258-622 |
4.99e-04 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 45.75 E-value: 4.99e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 258 ESRQGVASVQVTPEAPAAAQQGTESSAVLEKSPLKPMAPIPQDPAPRASDRERGQGEAPPQYLTDDLEFLRACHLPRSNS 337
Cdd:PRK07764 382 ERRLGVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAA 461
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 338 GAAPEAEVNAASQESCQQPVGAYLPHAElPWGLPSPALVPEAGGSGKEAlDTID-------------------------- 391
Cdd:PRK07764 462 PSAQPAPAPAAAPEPTAAPAPAPPAAPA-PAAAPAAPAAPAAPAGADDA-ATLRerwpeilaavpkrsrktwaillpeat 539
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 392 ---------VQGHPQTGMRG--TKPN-----------------QVVCVAAGGQPEGGLPVSPEP-SLLTPTEEAHPASSL 442
Cdd:PRK07764 540 vlgvrgdtlVLGFSTGGLARrfASPGnaevlvtalaeelggdwQVEAVVGPAPGAAGGEGPPAPaSSGPPEEAARPAAPA 619
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 443 ASF--PAAQIPIAVEEPGSSSRESVSKAGMPVSADAAKEVVDAGLVGLERQVSDLGSKGEHPEGDPGEVPAPSPQERGeh 520
Cdd:PRK07764 620 APAapAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAA-- 697
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 521 lnteQSHEVQPGVPPPPLPKEQSHEVQPGAPPPPLPKAPSESARG---------PPGPTDGAKVHEDSTSPAVAKEGSRS 591
Cdd:PRK07764 698 ----PAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPvplppepddPPDPAGAPAQPPPPPAPAPAAAPAAA 773
|
410 420 430
....*....|....*....|....*....|.
gi 578818737 592 PGDSPGGKEEAPEPPDGGDPGNLQGEDSQAF 622
Cdd:PRK07764 774 PPPSPPSEEEEMAEDDAPSMDDEDRRDAEEV 804
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
1543-2007 |
7.48e-04 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 45.31 E-value: 7.48e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 1543 PTLREDERPEGPGAAWPGLE----GQAYSQLERSRQELASGLPS-PAATQELPVERAAAFQVAPHSHGEEAVAQDRIPSG 1617
Cdd:PHA03247 2631 PSPAANEPDPHPPPTVPPPErprdDPAPGRVSRPRRARRLGRAAqASSPPQRPRRRAARPTVGSLTSLADPPPPPPTPEP 2710
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 1618 KQHQETSACDSPHGEDGPGDFAH----TGVPGHVPRSTCAPS----PQREVLTVPEANSEPWTLDTLGGERR--PGVTAG 1687
Cdd:PHA03247 2711 APHALVSATPLPPGPAAARQASPalpaAPAPPAVPAGPATPGgparPARPPTTAGPPAPAPPAAPAAGPPRRltRPAVAS 2790
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 1688 ILEMRNALGNQSTPAPPTGEV-ADTPLEPGKVAGAAGEAEGDITLSTAEtqACASGDLPEAGTTRTFSVVAGDLVLPGSC 1766
Cdd:PHA03247 2791 LSESRESLPSPWDPADPPAAVlAPAAALPPAASPAGPLPPPTSAQPTAP--PPPPGPPPPSLPLGGSVAPGGDVRRRPPS 2868
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 1767 QDPACSDKAPGMEGTAALHGDSPARPQQAKEQPGPERPIPagdgkvcvSSPPEPDETHDPKLQHLAPEELHTDRESPRPG 1846
Cdd:PHA03247 2869 RSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQPERP--------PQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQ 2940
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 1847 PSMLPSVPKKDAPRVMDKVtSDETRGAEGTESSPVADDIIQPAAPAdLESPTLAASSYHGDVVGQVSTdlIAQSISPAAA 1926
Cdd:PHA03247 2941 PPLAPTTDPAGAGEPSGAV-PQPWLGALVPGRVAVPRFRVPQPAPS-REAPASSTPPLTGHSLSRVSS--WASSLALHEE 3016
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 1927 HAGLPPSAAEHIVSPSAPAGDRVEASTPScpDPAKDLSRSSDSEeafeTPESTTPVKAPPAPPPPPPEVIPEPEVSTQPP 2006
Cdd:PHA03247 3017 TDPPPVSLKQTLWPPDDTEDSDADSLFDS--DSERSDLEALDPL----PPEPHDPFAHEPDPATPEAGARESPSSQFGPP 3090
|
.
gi 578818737 2007 P 2007
Cdd:PHA03247 3091 P 3091
|
|
| COG1340 |
COG1340 |
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]; |
2770-2903 |
8.50e-04 |
|
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
Pssm-ID: 440951 [Multi-domain] Cd Length: 297 Bit Score: 44.13 E-value: 8.50e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2770 ARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTI----AQMIE-----DEQREKSVS-HQTVQqlvlEKEQALA 2839
Cdd:COG1340 151 KAKKALEKNEKLKELRAELKELRKEAEEIHKKIKELAEEAqelhEEMIElykeaDELRKEADElHKEIV----EAQEKAD 226
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 578818737 2840 DLNsveKSLADLFRRYEKMKEVLEGFRKNEEVLKRcaqeylsrvKKEEQRYQALKVHAEEKLDR 2903
Cdd:COG1340 227 ELH---EEIIELQKELRELRKELKKLRKKQRALKR---------EKEKEELEEKAEEIFEKLKK 278
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
24-319 |
1.00e-03 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 44.78 E-value: 1.00e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 24 PPNPEPTQRTLSAQTPRSAQPPGNSQNIKrkqqdTPGSPDHRDASSIGSVGLGGFCTASESSASLDP----CLVSPEVTE 99
Cdd:PHA03307 67 PPTGPPPGPGTEAPANESRSTPTWSLSTL-----APASPAREGSPTPPGPSSPDPPPPTPPPASPPPspapDLSEMLRPV 141
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 100 PRKDPQGARGPEGSLLPSPPPSQEREHPSSSMPFAECPPEGCLASPAAAPEDGPQTQSPRREPAPNAPGDIAAAFPAERD 179
Cdd:PHA03307 142 GSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISASASSPA 221
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 180 SSTPYQEIAAVPSAGRERQPKEEGQKSSFSFSSGIDQSPGMSPVPLREPMKAPLCGEGDQPGGFESQEKEAAGGFPPAES 259
Cdd:PHA03307 222 PAPGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPS 301
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 578818737 260 RQGV--------ASVQVTPEAPAAAQQGTESSAVLEKSPLKPMAPI--------PQDPAPRASDRERGQGEAPPQY 319
Cdd:PHA03307 302 SPGSgpapssprASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPsrspspsrPPPPADPSSPRKRPRPSRAPSS 377
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
1768-2055 |
1.01e-03 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 44.78 E-value: 1.01e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 1768 DPACSDKAPGMEGTAAlhgDSPARPQQaKEQPGPERPIPAGDGKVcVSSPPEPDETHDPKLQHLAPEELHTDRESPRPGP 1847
Cdd:PHA03307 46 DSAELAAVTVVAGAAA---CDRFEPPT-GPPPGPGTEAPANESRS-TPTWSLSTLAPASPAREGSPTPPGPSSPDPPPPT 120
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 1848 SMLPSVPKKDAPRVmdkvtSDETRGAEGTESSPVADDIIQPAAPADLESPTlaASSYHGDVVGQVSTDLIAQSISPAAAh 1927
Cdd:PHA03307 121 PPPASPPPSPAPDL-----SEMLRPVGSPGPPPAASPPAAGASPAAVASDA--ASSRQAALPLSSPEETARAPSSPPAE- 192
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 1928 agLPPSAAEHIVSPSAPAGDRVEASTPSCPDP------AKDLSRSSDSEEAFETPESTTPVKAPPAPPPPPPEVIPEPEV 2001
Cdd:PHA03307 193 --PPPSTPPAAASPRPPRRSSPISASASSPAPapgrsaADDAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIW 270
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 578818737 2002 STQPP-PEEPGCGSE----TVPVPDGPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSGT 2055
Cdd:PHA03307 271 EASGWnGPSSRPGPAssssSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSST 329
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
241-715 |
1.01e-03 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 44.78 E-value: 1.01e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 241 GGFESQEKEAAGGFPPAESRQGVASVQVTPEAPAAAqqgtesSAVLEKSPLKPMAPIPQDPAPRASDRERGQGEAPP--- 317
Cdd:PHA03307 17 GGEFFPRPPATPGDAADDLLSGSQGQLVSDSAELAA------VTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTptw 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 318 QYLTDDLEFLRACHLPRSNSGAAPEAEVNAASQESCQQPVGAYLPHAELPWGLPSPALVPEAGGSGkealdtidvqghpq 397
Cdd:PHA03307 91 SLSTLAPASPAREGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGPPPAASPPAAG-------------- 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 398 tgmrgtkpnqvvcvAAGGQPEGGLPVSPEPSLLTPTEEAH---PASSLASFPAAQIPIAVEEPGSS-SRESVSKAGMPVS 473
Cdd:PHA03307 157 --------------ASPAAVASDAASSRQAALPLSSPEETaraPSSPPAEPPPSTPPAAASPRPPRrSSPISASASSPAP 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 474 ADAAKEVVDAG-----LVGLERQVSDLGSKGEHPEGDPGEVPAPSPQERGEHLNTEQShevqpgvpppplpkEQSHEVQP 548
Cdd:PHA03307 223 APGRSAADDAGasssdSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSS--------------RPGPASSS 288
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 549 GAPPPPLPKAPSESARGPPGPTDGAKVHEDSTSPAVAKEGSRSPGDSPGGKEEAPEPPDGGDPGNLQGEDSQAFSSKRDP 628
Cdd:PHA03307 289 SSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSESSRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKR 368
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 629 EvgkdelskPSSDAESRDHPSSHSAQPPRKGGAGHTDGPHSQTAEADASGLPHKLGEEDPVLPPVPDGAGEPTVPEGAIW 708
Cdd:PHA03307 369 P--------RPSRAPSSPAASAGRPTRRRARAAVAGRARRRDATGRFPAGRPRPSPLDAGAASGAFYARYPLLTPSGEPW 440
|
....*..
gi 578818737 709 EGSGLQP 715
Cdd:PHA03307 441 PGSPPPP 447
|
|
| TPH |
pfam13868 |
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of ... |
2770-2949 |
1.60e-03 |
|
Trichohyalin-plectin-homology domain; This family is a mixtrue of two different families of eukaryotic proteins. Trichoplein or mitostatin, was first defined as a meiosis-specific nuclear structural protein. It has since been linked with mitochondrial movement. It is associated with the mitochondrial outer membrane, and over-expression leads to reduction in mitochondrial motility whereas lack of it enhances mitochondrial movement. The activity appears to be mediated through binding the mitochondria to the actin intermediate filaments (IFs). The family is in the trichohyalin-plectin-homology domain.
Pssm-ID: 464007 [Multi-domain] Cd Length: 341 Bit Score: 43.37 E-value: 1.60e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2770 ARAEIITKEREVSEWKDKYEEsrREVMEMRKIvAEYEKTIAQ---MIEDEQREKSVSHQTVQQLVL-----------EKE 2835
Cdd:pfam13868 128 LREEIDEFNEEQAEWKELEKE--EEREEDERI-LEYLKEKAEreeEREAEREEIEEEKEREIARLRaqqekaqdekaERD 204
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2836 QALADLNSVE-------KSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYlsRVKKEEQRYQALKVHAE-EKLDRANAE 2907
Cdd:pfam13868 205 ELRAKLYQEEqerkerqKEREEAEKKARQRQELQQAREEQIELKERRLAEE--AEREEEEFERMLRKQAEdEEIEQEEAE 282
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 578818737 2908 iaQVRGKAQQEQAAHQASLR-KEQLRVDALERTLEQKNKEIEE 2949
Cdd:pfam13868 283 --KRRMKRLEHRRELEKQIEeREEQRAAEREEELEEGERLREE 323
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
2685-2877 |
2.02e-03 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 43.60 E-value: 2.02e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2685 KNPPLFAQKLqEELEfaimriEALKLARQIALASRSHQDAKREA-AHPTDVSISKTALYSRIGTAEVEKPAGLLFQQpdl 2763
Cdd:COG4717 64 RKPELNLKEL-KELE------EELKEAEEKEEEYAELQEELEELeEELEELEAELEELREELEKLEKLLQLLPLYQE--- 133
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2764 dsaLQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQTVQQLVLEKEQALADLNS 2843
Cdd:COG4717 134 ---LEALEAELAELPERLEELEERLEELRELEEELEELEAELAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAE 210
|
170 180 190
....*....|....*....|....*....|....
gi 578818737 2844 VEKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQ 2877
Cdd:COG4717 211 LEEELEEAQEELEELEEELEQLENELEAAALEER 244
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
2787-2963 |
2.35e-03 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 42.97 E-value: 2.35e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2787 KYEESRREVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQTVQQLVLEKEQALADLNSVEKSLADLFRRYEKMKEVLEgfR 2866
Cdd:COG4372 7 KVGKARLSLFGLRPKTGILIAALSEQLRKALFELDKLQEELEQLREELEQAREELEQLEEELEQARSELEQLEEELE--E 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2867 KNEEVLKrcAQEYLSRVKKEEQRYQALKVHAEEKLDRANAEIAQVRgkaqqeqaahqasLRKEQL--RVDALERTLEQKN 2944
Cdd:COG4372 85 LNEQLQA--AQAELAQAQEELESLQEEAEELQEELEELQKERQDLE-------------QQRKQLeaQIAELQSEIAERE 149
|
170
....*....|....*....
gi 578818737 2945 KEIEELTKICDELIAKMGK 2963
Cdd:COG4372 150 EELKELEEQLESLQEELAA 168
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
2765-2952 |
2.42e-03 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 43.47 E-value: 2.42e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2765 SALQIARAEIITKE--REVSEWKDKYEESRREVMEMRKIVAEYEKTIAQM-------------IEDEQREKsvsHQTVQQ 2829
Cdd:TIGR04523 298 SDLNNQKEQDWNKElkSELKNQEKKLEEIQNQISQNNKIISQLNEQISQLkkeltnsesenseKQRELEEK---QNEIEK 374
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2830 LVLEKEQALADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKrcaQEYLSrVKKEEQRYQALKVHAEEKLDRANAEIA 2909
Cdd:TIGR04523 375 LKKENQSYKQEIKNLESQINDLESKIQNQEKLNQQKDEQIKKLQ---QEKEL-LEKEIERLKETIIKNNSEIKDLTNQDS 450
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 578818737 2910 ----------QVRGKAQQEQAAHQASLRKEQLRVDALERTLEQKNKEIEELTK 2952
Cdd:TIGR04523 451 vkeliiknldNTRESLETQLKVLSRSINKIKQNLEQKQKELKSKEKELKKLNE 503
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
2771-2956 |
3.12e-03 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 43.42 E-value: 3.12e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2771 RAEIITKEREVsewkdkyEESRREVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQTV--QQLVLEKEQALADLNSVEKSL 2848
Cdd:pfam02463 185 LAELIIDLEEL-------KLQELKLKEQAKKALEYYQLKEKLELEEEYLLYLDYLKLneERIDLLQELLRDEQEEIESSK 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2849 ADLFRRYEKMKEVLEGFRKNEEVLK-----------RCAQEYLSRVKKEEQRYQALK--VHAEEKLDRANAEIAQVRGKA 2915
Cdd:pfam02463 258 QEIEKEEEKLAQVLKENKEEEKEKKlqeeelkllakEEEELKSELLKLERRKVDDEEklKESEKEKKKAEKELKKEKEEI 337
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 578818737 2916 QQEQAAHQASLRKEQL----RVDALERTLEQKNKEIEELTKICDE 2956
Cdd:pfam02463 338 EELEKELKELEIKREAeeeeEEELEKLQEKLEQLEEELLAKKKLE 382
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
89-306 |
3.37e-03 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 43.24 E-value: 3.37e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 89 DPCLVSPEVTEPRKDPQGARGPEGSLLPSPPPSQEREHPSSSMPFAECPPEGCLASPAAA-PEDGPQTQSPRREPAPNAP 167
Cdd:PHA03307 52 AVTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPsSPDPPPPTPPPASPPPSPA 131
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 168 GDIAAAFPAERDSSTPYQEIAAVPSAGRERQPKEEGQKSSFSFSSGIDQSPGMSPVPLRE--PMKAPLCGEGDQPGGFES 245
Cdd:PHA03307 132 PDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPEETARAPSSPPAepPPSTPPAAASPRPPRRSS 211
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 578818737 246 QEKEAAGGFPPAESRQGVASVQVTPEAPAAAQQGTESSAVLEKSPLKPMAPIPQDPAPRAS 306
Cdd:PHA03307 212 PISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEA 272
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
1647-2037 |
4.54e-03 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 43.00 E-value: 4.54e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 1647 VPRSTCAPSPQREVLTV----PEANSEPWTLDTLGGERRPgvtagilemrNALGNQSTPAPPTGEVADTPlePGKVAGAA 1722
Cdd:PHA03247 2568 VPPPRPAPRPSEPAVTSrarrPDAPPQSARPRAPVDDRGD----------PRGPAPPSPLPPDTHAPDPP--PPSPSPAA 2635
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 1723 GEAEGDITLSTAETQ----ACASGDLPEAGTTRTFSVVAGDLVLPGSCQDPACSDKAPGMEGTAALHgDSPARPQQAKEQ 1798
Cdd:PHA03247 2636 NEPDPHPPPTVPPPErprdDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPP-PPPPTPEPAPHA 2714
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 1799 PGPERPIPAGDGKVCVSSPPEPDETHDPKlqhlAPEELHTDRESPRPGPSMLPSVPKKDAPrvmdkvtsdetrgAEGTES 1878
Cdd:PHA03247 2715 LVSATPLPPGPAAARQASPALPAAPAPPA----VPAGPATPGGPARPARPPTTAGPPAPAP-------------PAAPAA 2777
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 1879 SPVADDIIQPAAPADLESPTLAASSYHGDVVGQVSTDLIAQSISPAAAhAGLPPSAAEHIVSPSAPAGDrVEASTPSCPD 1958
Cdd:PHA03247 2778 GPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPA-GPLPPPTSAQPTAPPPPPGP-PPPSLPLGGS 2855
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 1959 --PAKDLSRSSDSEEAFETPESTTPV-----KAPPAPPPPPPEVIPEPEVSTQPPPEEPGCGSETVPVPDGPRSDSVEGS 2031
Cdd:PHA03247 2856 vaPGGDVRRRPPSRSPAAKPAAPARPpvrrlARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPP 2935
|
....*.
gi 578818737 2032 PFRPPS 2037
Cdd:PHA03247 2936 PPRPQP 2941
|
|
| YqiK |
COG2268 |
Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown]; |
2743-2914 |
4.91e-03 |
|
Uncharacterized membrane protein YqiK, contains Band7/PHB/SPFH domain [Function unknown];
Pssm-ID: 441869 [Multi-domain] Cd Length: 439 Bit Score: 42.17 E-value: 4.91e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2743 SRIGTAEVEKpagllfqqpdlDSALQIARAEiitKEREVSEwkdkyEESRREVMEMRkiVAEYEKTIAQMIEDEQREKsv 2822
Cdd:COG2268 201 ARIAEAEAER-----------ETEIAIAQAN---REAEEAE-----LEQEREIETAR--IAEAEAELAKKKAEERREA-- 257
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2823 shqtvqqlvlEKEQALADLnSVEKsladlfRRYEKMKEV---LEGFRKNEEVLkrcAQEylSRVKKEEQRYQA---LKVH 2896
Cdd:COG2268 258 ----------ETARAEAEA-AYEI------AEANAEREVqrqLEIAEREREIE---LQE--KEAEREEAELEAdvrKPAE 315
|
170 180
....*....|....*....|..
gi 578818737 2897 AE----EKLDRANAEIAQVRGK 2914
Cdd:COG2268 316 AEkqaaEAEAEAEAEAIRAKGL 337
|
|
| DR0291 |
COG1579 |
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General ... |
2762-2961 |
5.15e-03 |
|
Predicted nucleic acid-binding protein DR0291, contains C4-type Zn-ribbon domain [General function prediction only];
Pssm-ID: 441187 [Multi-domain] Cd Length: 236 Bit Score: 41.45 E-value: 5.15e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2762 DLDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEyektiaqmIEDEQREKSVSHQTVQQLVLEKEQALA-- 2839
Cdd:COG1579 14 ELDSELDRLEHRLKELPAELAELEDELAALEARLEAAKTELED--------LEKEIKRLELEIEEVEARIKKYEEQLGnv 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2840 ----DLNSVEKSLADLfrryEKMKEVLEgfrknEEVLkrcaqeylsrvkkeeqryqalkvHAEEKLDRANAEIAQVRGKA 2915
Cdd:COG1579 86 rnnkEYEALQKEIESL----KRRISDLE-----DEIL-----------------------ELMERIEELEEELAELEAEL 133
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 578818737 2916 QQeqaahqaslRKEQLR--VDALERTLEQKNKEIEELTKICDELIAKM 2961
Cdd:COG1579 134 AE---------LEAELEekKAELDEELAELEAELEELEAEREELAAKI 172
|
|
| COG4913 |
COG4913 |
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown]; |
2827-2951 |
5.22e-03 |
|
Uncharacterized conserved protein, contains a C-terminal ATPase domain [Function unknown];
Pssm-ID: 443941 [Multi-domain] Cd Length: 1089 Bit Score: 42.59 E-value: 5.22e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2827 VQQLVLEKEQALADLNsvekSLADLFRRYEKMKEVLEGFRKNEEVLKRC---AQEYLS-RVKKEEQRYQALKVH---AEE 2899
Cdd:COG4913 213 VREYMLEEPDTFEAAD----ALVEHFDDLERAHEALEDAREQIELLEPIrelAERYAAaRERLAELEYLRAALRlwfAQR 288
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 578818737 2900 KLDRANAEIAQVRgkaqqeqaahqASLRKEQLRVDALERTLEQKNKEIEELT 2951
Cdd:COG4913 289 RLELLEAELEELR-----------AELARLEAELERLEARLDALREELDELE 329
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
2763-2957 |
6.09e-03 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 42.31 E-value: 6.09e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2763 LDSALQIARAEIitkeREVSEW-KDKYEESRREVMEMRKIVAEYEKtiAQMIEDEQREKSVSHQTVQQLVLEKEQALADL 2841
Cdd:COG3206 162 LEQNLELRREEA----RKALEFlEEQLPELRKELEEAEAALEEFRQ--KNGLVDLSEEAKLLLQQLSELESQLAEARAEL 235
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2842 NSVEKSLADLFRRYEKMKEVLEGFRKNEEVlkrcaQEYLSRVKKEEQRYQALKVHAEEK---LDRANAEIAQVRGKAQQE 2918
Cdd:COG3206 236 AEAEARLAALRAQLGSGPDALPELLQSPVI-----QQLRAQLAELEAELAELSARYTPNhpdVIALRAQIAALRAQLQQE 310
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 578818737 2919 QAAHQASLRKE----QLRVDALERTLEQKNKEIEELTKICDEL 2957
Cdd:COG3206 311 AQRILASLEAElealQAREASLQAQLAQLEARLAELPELEAEL 353
|
|
| PRK04778 |
PRK04778 |
septation ring formation regulator EzrA; Provisional |
2749-2958 |
7.51e-03 |
|
septation ring formation regulator EzrA; Provisional
Pssm-ID: 179877 [Multi-domain] Cd Length: 569 Bit Score: 41.75 E-value: 7.51e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2749 EVEKpagllfQQPDLDSALQIARAEIITKEREVSEWKDKYEESRREVMEMRKIVAEYEKTIAQMIEDEQR--EKSVSHQT 2826
Cdd:PRK04778 307 YVEK------NSDTLPDFLEHAKEQNKELKEEIDRVKQSYTLNESELESVRQLEKQLESLEKQYDEITERiaEQEIAYSE 380
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2827 VQqlvlekeqalADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLS-------RVKKEE-----QRYQALK 2894
Cdd:PRK04778 381 LQ----------EELEEILKQLEEIEKEQEKLSEMLQGLRKDELEAREKLERYRNklheikrYLEKSNlpglpEDYLEMF 450
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 578818737 2895 VHAEEKLDRANAEIAQVRgkaqqeqaahqaslrkeqLRVDALERTLEQKNKEIEELTKICDELI 2958
Cdd:PRK04778 451 FEVSDEIEALAEELEEKP------------------INMEAVNRLLEEATEDVETLEEETEELV 496
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
2759-2962 |
7.81e-03 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 41.95 E-value: 7.81e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2759 QQPDLDSalQIARAEIITK-EREVSEWKDKYEESRREVMEMRKIVAEYEKTI------AQMIEDEQREKSVSHQTVQQLV 2831
Cdd:PRK02224 490 EVEEVEE--RLERAEDLVEaEDRIERLEERREDLEELIAERRETIEEKRERAeelrerAAELEAEAEEKREAAAEAEEEA 567
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2832 LEKEQALADLNSVEKSLADLFRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRVKKEEQRYQALKvhaeEKLDRanaeIAQV 2911
Cdd:PRK02224 568 EEAREEVAELNSKLAELKERIESLERIRTLLAAIADAEDEIERLREKREALAELNDERRERLA----EKRER----KREL 639
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 578818737 2912 RGKAQQEqaahqaslRKEQLRVDA--LERTLEQKNKEIEELTKICDELIAKMG 2962
Cdd:PRK02224 640 EAEFDEA--------RIEEAREDKerAEEYLEQVEEKLDELREERDDLQAEIG 684
|
|
| sbcc |
TIGR00618 |
exonuclease SbcC; All proteins in this family for which functions are known are part of an ... |
2775-2963 |
7.89e-03 |
|
exonuclease SbcC; All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 129705 [Multi-domain] Cd Length: 1042 Bit Score: 41.88 E-value: 7.89e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2775 ITKEREVSEWKDKYE----ESRREVMEMRKIVAEYEKTIAQMIEDEQREKSVSHQT-VQQLVLEKEQALADLNSVEKSLA 2849
Cdd:TIGR00618 245 LTQKREAQEEQLKKQqllkQLRARIEELRAQEAVLEETQERINRARKAAPLAAHIKaVTQIEQQAQRIHTELQSKMRSRA 324
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 578818737 2850 DLFRRY----------EKMKEVLEGFRKNEEVLKRCAQ------EYLSRVKKEEQRYQAL---KVHAEEKLDRANAEIAQ 2910
Cdd:TIGR00618 325 KLLMKRaahvkqqssiEEQRRLLQTLHSQEIHIRDAHEvatsirEISCQQHTLTQHIHTLqqqKTTLTQKLQSLCKELDI 404
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 578818737 2911 VRgKAQQEQAAHQASLRKEQLRVDALERT--LEQKNKEIEELTKICDELIAKMGK 2963
Cdd:TIGR00618 405 LQ-REQATIDTRTSAFRDLQGQLAHAKKQqeLQQRYAELCAAAITCTAQCEKLEK 458
|
|
| |
