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Conserved domains on  [gi|688618000|ref|XP_009296497|]
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excitatory amino acid transporter 2 isoform X1 [Danio rerio]

Protein Classification

dicarboxylate/amino acid:cation symporter( domain architecture ID 10448728)

dicarboxylate/amino acid:cation symporter facilitates H+ or Na+ symport with C4-dicarboxylates, dicarboxylic amino acids (aspartate, glutamate) or other amino acids; belongs to the sodium:dicarboxylate symporter family

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SDF pfam00375
Sodium:dicarboxylate symporter family;
38-482 1.22e-123

Sodium:dicarboxylate symporter family;


:

Pssm-ID: 425646 [Multi-domain]  Cd Length: 388  Bit Score: 367.23  E-value: 1.22e-123
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688618000   38 LLTLTVMGVIMGAVSGMLLrvaspidDNIVMVIAFPGDILMRMLKMLILPLIISSLITGLAGL-DAKSSGRLGSRAMIYY 116
Cdd:pfam00375   1 LLLQILIALVLGILIGLFF-------PELAAWLKPLGDLFIRLLKMIIVPLIFASIISGIASLgDGKKLGKLGGKTLLYF 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688618000  117 MTTTVIAAVLGVILVLLIHPGNPKLkeNLGEGLENDEVSSLDAFFDLIRNLFPENLVQACFQQiqtvvkkvevqpdlddt 196
Cdd:pfam00375  74 LVTTAIAALIGLLVANVFQPGSGLA--LIAASLKEAKAAEAPSLLDFILNIIPSNIFEALAEG----------------- 134

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688618000  197 nstmseylsnatkpppifkdkkslqfksgmNVLGLIGFFIAFGICMGKMGEKARLMIDFFNILNEIVMKLVIMIMWYSPF 276
Cdd:pfam00375 135 ------------------------------NVLAVIVFAILFGIALAALGEKGEPLLNFIESLQEVMMKVIGWVMKLAPI 184

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688618000  277 GIACLICGKIISIkDLEVVArQLGMYMITVIVGLIIHGAIFLPCIYFAIVRKNPFSFFMGIFQAWITALGTASSAGTLPV 356
Cdd:pfam00375 185 GVFALIANTVGTY-GLGILS-SLAKFLLVVYLGLAIHLLIVYPLLIKFLGKVNPFKFLKKMLPALLTAFSTASSAATLPV 262

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688618000  357 TFRCLEENLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGIDLDPGQIVTVSLTATLASVGAASIPSAGLVTM 436
Cdd:pfam00375 263 TLECAEKNLGVSESIASFVLPLGATINMDGTAIYLAVAAIFIAQAYGVDLSFGQQLTLVLTATLASIGAAGVPGGGLVAL 342

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*.
gi 688618000  437 LLILTAVGLPTQDISLLVAVDWLLDRFRTSVNVVGDSYGAGIVYHL 482
Cdd:pfam00375 343 GLVLSALGLPLEGIALILAIDRLLDMFRTAVNVTGDAAAAVIVAKL 388
 
Name Accession Description Interval E-value
SDF pfam00375
Sodium:dicarboxylate symporter family;
38-482 1.22e-123

Sodium:dicarboxylate symporter family;


Pssm-ID: 425646 [Multi-domain]  Cd Length: 388  Bit Score: 367.23  E-value: 1.22e-123
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688618000   38 LLTLTVMGVIMGAVSGMLLrvaspidDNIVMVIAFPGDILMRMLKMLILPLIISSLITGLAGL-DAKSSGRLGSRAMIYY 116
Cdd:pfam00375   1 LLLQILIALVLGILIGLFF-------PELAAWLKPLGDLFIRLLKMIIVPLIFASIISGIASLgDGKKLGKLGGKTLLYF 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688618000  117 MTTTVIAAVLGVILVLLIHPGNPKLkeNLGEGLENDEVSSLDAFFDLIRNLFPENLVQACFQQiqtvvkkvevqpdlddt 196
Cdd:pfam00375  74 LVTTAIAALIGLLVANVFQPGSGLA--LIAASLKEAKAAEAPSLLDFILNIIPSNIFEALAEG----------------- 134

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688618000  197 nstmseylsnatkpppifkdkkslqfksgmNVLGLIGFFIAFGICMGKMGEKARLMIDFFNILNEIVMKLVIMIMWYSPF 276
Cdd:pfam00375 135 ------------------------------NVLAVIVFAILFGIALAALGEKGEPLLNFIESLQEVMMKVIGWVMKLAPI 184

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688618000  277 GIACLICGKIISIkDLEVVArQLGMYMITVIVGLIIHGAIFLPCIYFAIVRKNPFSFFMGIFQAWITALGTASSAGTLPV 356
Cdd:pfam00375 185 GVFALIANTVGTY-GLGILS-SLAKFLLVVYLGLAIHLLIVYPLLIKFLGKVNPFKFLKKMLPALLTAFSTASSAATLPV 262

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688618000  357 TFRCLEENLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGIDLDPGQIVTVSLTATLASVGAASIPSAGLVTM 436
Cdd:pfam00375 263 TLECAEKNLGVSESIASFVLPLGATINMDGTAIYLAVAAIFIAQAYGVDLSFGQQLTLVLTATLASIGAAGVPGGGLVAL 342

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*.
gi 688618000  437 LLILTAVGLPTQDISLLVAVDWLLDRFRTSVNVVGDSYGAGIVYHL 482
Cdd:pfam00375 343 GLVLSALGLPLEGIALILAIDRLLDMFRTAVNVTGDAAAAVIVAKL 388
GltP COG1301
Na+/H+-dicarboxylate symporter [Energy production and conversion];
34-479 1.23e-123

Na+/H+-dicarboxylate symporter [Energy production and conversion];


Pssm-ID: 440912 [Multi-domain]  Cd Length: 406  Bit Score: 367.90  E-value: 1.23e-123
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688618000  34 RKNLLLTLTVMGVIMGAVSGMLLRvaspidDNIVMVIAFPGDILMRMLKMLILPLIISSLITGLAGL-DAKSSGRLGSRA 112
Cdd:COG1301    1 FKLSLTLQILIALVLGILLGLLLP------ELVAAVLKPLGDIFINLLKMIVVPLVFFSIVVGIASLgDLKKLGRIGGKT 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688618000 113 MIYYMTTTVIAAVLGVILVLLIHPGNPkLKENLGEGLENDEVSSLDaFFDLIRNLFPENLVQAcfqqiqtvvkkvevqpd 192
Cdd:COG1301   75 LLYFLVTTTIALVIGLVVANLFQPGAG-LNLDLADAAAAEAAEAPS-LLDFLLNIIPSNIFEA----------------- 135

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688618000 193 lddtnstMSEylsnatkpppifkdkkslqfksgMNVLGLIGFFIAFGICMGKMGEKARLMIDFFNILNEIVMKLVIMIMW 272
Cdd:COG1301  136 -------FAE-----------------------GNMLQIIFFAILFGIALAALGEKGKPLLDFFESLSEVMFKIVGWVMK 185

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688618000 273 YSPFGIACLIcGKIISIKDLEVVArQLGMYMITVIVGLIIHGAIFLPCIYFAIVRKNPFSFFMGIFQAWITALGTASSAG 352
Cdd:COG1301  186 LAPIGVFALI-AATVAKYGLDALG-SLGKLVLTVYLALLLHLFVVLPLILRLLTGLSPLKFLRAIRPALLLAFSTSSSEA 263

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688618000 353 TLPVTFRCLEENLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGIDLDPGQIVTVSLTATLASVGAASIPSAG 432
Cdd:COG1301  264 TLPVTMEKAEEKLGVSKSVASFVLPLGATINMDGTAIYQAVAALFIAQAYGIDLSLGQQLTIVLTAVLASIGAAGVPGAG 343

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|....*..
gi 688618000 433 LVTMLLILTAVGLPTQDISLLVAVDWLLDRFRTSVNVVGDSYGAGIV 479
Cdd:COG1301  344 LVMLAAVLSAVGLPLEGIALILGIDRILDMARTAVNVTGDAVATVVV 390
PRK01663 PRK01663
C4-dicarboxylate transporter DctA; Reviewed
 33-488 1.88e-44

C4-dicarboxylate transporter DctA; Reviewed


Pssm-ID: 234968 [Multi-domain]  Cd Length: 428  Bit Score: 162.38  E-value: 1.88e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688618000  33 MRKNLLLTLTVMgVIMGAVSGMLLRVASPiddNIVMVIAFPGDILMRMLKMLILPLIISSLITGLAGL-DAKSSGRLGSR 111
Cdd:PRK01663   1 MKKPLYKSLYFQ-VLVAIIIGILLGHFYP---ELGAQMKPLGDGFIKLIKMIIAPIIFCTVVTGIAGMgDMKKVGRVGGK 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688618000 112 AMIYYMTTTVIAAVLGVILVLLIHPGnpklkenlgEGLeNDEVSSLDA--------------FFDLIRNLFPENLVQAcf 177
Cdd:PRK01663  77 ALLYFEIVSTIALIIGLIVVNVVQPG---------AGM-NIDPATLDAkavaqyaaqaheqgTVDFLMDIIPTTVVGA-- 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688618000 178 qqiqtvvkkvevqpdlddtnstmseylsnatkpppifkdkkslqFKSGmNVLGLIGFFIAFGICMGKMGEKARLMIDFFN 257
Cdd:PRK01663 145 --------------------------------------------FASG-DILQVLLFAVLFGFALARLGEKGKPVFDFIE 179

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688618000 258 ILNEIVMKLVIMIMWYSP---FGIACLICGK--IISIKdlevvarQLGMYMITVIVGLIIhgaiFLPCIYFAIVRKNPFS 332
Cdd:PRK01663 180 SLSHVLFGIVNMIMKLAPigaFGAMAFTIGKygVGSLV-------QLGQLIGCFYITCIL----FVFVVLGAIARLTGFS 248

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688618000 333 FFMgiFQAWITA-----LGTASSAGTLPVTFRCLEeNLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGIDLD 407
Cdd:PRK01663 249 IFK--FIRYIKEellivLGTSSSESALPRMMEKME-KLGCKKSVVGLVIPTGYSFNLDGTSIYLTMAAVFIAQATNTPLS 325

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688618000 408 PGQIVTVSLTATLASVGAASIPSAGLVTMLLILTAVG-LPTQDISLLVAVDWLLDRFRTSVNVVGDSYgAGIVYHLSKAE 486
Cdd:PRK01663 326 IGHQITLLAVLLLTSKGAAGVTGSGFIVLAATLSAVPhIPVAGLALILGIDRFMSEARALTNLIGNGV-ATVVVAKWEKE 404


                 ..
gi 688618000 487 LD 488
Cdd:PRK01663 405 LD 406
 
Name Accession Description Interval E-value
SDF pfam00375
Sodium:dicarboxylate symporter family;
38-482 1.22e-123

Sodium:dicarboxylate symporter family;


Pssm-ID: 425646 [Multi-domain]  Cd Length: 388  Bit Score: 367.23  E-value: 1.22e-123
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688618000   38 LLTLTVMGVIMGAVSGMLLrvaspidDNIVMVIAFPGDILMRMLKMLILPLIISSLITGLAGL-DAKSSGRLGSRAMIYY 116
Cdd:pfam00375   1 LLLQILIALVLGILIGLFF-------PELAAWLKPLGDLFIRLLKMIIVPLIFASIISGIASLgDGKKLGKLGGKTLLYF 73

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688618000  117 MTTTVIAAVLGVILVLLIHPGNPKLkeNLGEGLENDEVSSLDAFFDLIRNLFPENLVQACFQQiqtvvkkvevqpdlddt 196
Cdd:pfam00375  74 LVTTAIAALIGLLVANVFQPGSGLA--LIAASLKEAKAAEAPSLLDFILNIIPSNIFEALAEG----------------- 134

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688618000  197 nstmseylsnatkpppifkdkkslqfksgmNVLGLIGFFIAFGICMGKMGEKARLMIDFFNILNEIVMKLVIMIMWYSPF 276
Cdd:pfam00375 135 ------------------------------NVLAVIVFAILFGIALAALGEKGEPLLNFIESLQEVMMKVIGWVMKLAPI 184

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688618000  277 GIACLICGKIISIkDLEVVArQLGMYMITVIVGLIIHGAIFLPCIYFAIVRKNPFSFFMGIFQAWITALGTASSAGTLPV 356
Cdd:pfam00375 185 GVFALIANTVGTY-GLGILS-SLAKFLLVVYLGLAIHLLIVYPLLIKFLGKVNPFKFLKKMLPALLTAFSTASSAATLPV 262

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688618000  357 TFRCLEENLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGIDLDPGQIVTVSLTATLASVGAASIPSAGLVTM 436
Cdd:pfam00375 263 TLECAEKNLGVSESIASFVLPLGATINMDGTAIYLAVAAIFIAQAYGVDLSFGQQLTLVLTATLASIGAAGVPGGGLVAL 342

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|....*.
gi 688618000  437 LLILTAVGLPTQDISLLVAVDWLLDRFRTSVNVVGDSYGAGIVYHL 482
Cdd:pfam00375 343 GLVLSALGLPLEGIALILAIDRLLDMFRTAVNVTGDAAAAVIVAKL 388
GltP COG1301
Na+/H+-dicarboxylate symporter [Energy production and conversion];
34-479 1.23e-123

Na+/H+-dicarboxylate symporter [Energy production and conversion];


Pssm-ID: 440912 [Multi-domain]  Cd Length: 406  Bit Score: 367.90  E-value: 1.23e-123
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688618000  34 RKNLLLTLTVMGVIMGAVSGMLLRvaspidDNIVMVIAFPGDILMRMLKMLILPLIISSLITGLAGL-DAKSSGRLGSRA 112
Cdd:COG1301    1 FKLSLTLQILIALVLGILLGLLLP------ELVAAVLKPLGDIFINLLKMIVVPLVFFSIVVGIASLgDLKKLGRIGGKT 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688618000 113 MIYYMTTTVIAAVLGVILVLLIHPGNPkLKENLGEGLENDEVSSLDaFFDLIRNLFPENLVQAcfqqiqtvvkkvevqpd 192
Cdd:COG1301   75 LLYFLVTTTIALVIGLVVANLFQPGAG-LNLDLADAAAAEAAEAPS-LLDFLLNIIPSNIFEA----------------- 135

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688618000 193 lddtnstMSEylsnatkpppifkdkkslqfksgMNVLGLIGFFIAFGICMGKMGEKARLMIDFFNILNEIVMKLVIMIMW 272
Cdd:COG1301  136 -------FAE-----------------------GNMLQIIFFAILFGIALAALGEKGKPLLDFFESLSEVMFKIVGWVMK 185

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688618000 273 YSPFGIACLIcGKIISIKDLEVVArQLGMYMITVIVGLIIHGAIFLPCIYFAIVRKNPFSFFMGIFQAWITALGTASSAG 352
Cdd:COG1301  186 LAPIGVFALI-AATVAKYGLDALG-SLGKLVLTVYLALLLHLFVVLPLILRLLTGLSPLKFLRAIRPALLLAFSTSSSEA 263

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688618000 353 TLPVTFRCLEENLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGIDLDPGQIVTVSLTATLASVGAASIPSAG 432
Cdd:COG1301  264 TLPVTMEKAEEKLGVSKSVASFVLPLGATINMDGTAIYQAVAALFIAQAYGIDLSLGQQLTIVLTAVLASIGAAGVPGAG 343

                        410       420       430       440
                 ....*....|....*....|....*....|....*....|....*..
gi 688618000 433 LVTMLLILTAVGLPTQDISLLVAVDWLLDRFRTSVNVVGDSYGAGIV 479
Cdd:COG1301  344 LVMLAAVLSAVGLPLEGIALILGIDRILDMARTAVNVTGDAVATVVV 390
PRK01663 PRK01663
C4-dicarboxylate transporter DctA; Reviewed
 33-488 1.88e-44

C4-dicarboxylate transporter DctA; Reviewed


Pssm-ID: 234968 [Multi-domain]  Cd Length: 428  Bit Score: 162.38  E-value: 1.88e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688618000  33 MRKNLLLTLTVMgVIMGAVSGMLLRVASPiddNIVMVIAFPGDILMRMLKMLILPLIISSLITGLAGL-DAKSSGRLGSR 111
Cdd:PRK01663   1 MKKPLYKSLYFQ-VLVAIIIGILLGHFYP---ELGAQMKPLGDGFIKLIKMIIAPIIFCTVVTGIAGMgDMKKVGRVGGK 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688618000 112 AMIYYMTTTVIAAVLGVILVLLIHPGnpklkenlgEGLeNDEVSSLDA--------------FFDLIRNLFPENLVQAcf 177
Cdd:PRK01663  77 ALLYFEIVSTIALIIGLIVVNVVQPG---------AGM-NIDPATLDAkavaqyaaqaheqgTVDFLMDIIPTTVVGA-- 144

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688618000 178 qqiqtvvkkvevqpdlddtnstmseylsnatkpppifkdkkslqFKSGmNVLGLIGFFIAFGICMGKMGEKARLMIDFFN 257
Cdd:PRK01663 145 --------------------------------------------FASG-DILQVLLFAVLFGFALARLGEKGKPVFDFIE 179

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688618000 258 ILNEIVMKLVIMIMWYSP---FGIACLICGK--IISIKdlevvarQLGMYMITVIVGLIIhgaiFLPCIYFAIVRKNPFS 332
Cdd:PRK01663 180 SLSHVLFGIVNMIMKLAPigaFGAMAFTIGKygVGSLV-------QLGQLIGCFYITCIL----FVFVVLGAIARLTGFS 248

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688618000 333 FFMgiFQAWITA-----LGTASSAGTLPVTFRCLEeNLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGIDLD 407
Cdd:PRK01663 249 IFK--FIRYIKEellivLGTSSSESALPRMMEKME-KLGCKKSVVGLVIPTGYSFNLDGTSIYLTMAAVFIAQATNTPLS 325

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688618000 408 PGQIVTVSLTATLASVGAASIPSAGLVTMLLILTAVG-LPTQDISLLVAVDWLLDRFRTSVNVVGDSYgAGIVYHLSKAE 486
Cdd:PRK01663 326 IGHQITLLAVLLLTSKGAAGVTGSGFIVLAATLSAVPhIPVAGLALILGIDRFMSEARALTNLIGNGV-ATVVVAKWEKE 404


                 ..
gi 688618000 487 LD 488
Cdd:PRK01663 405 LD 406
gltP PRK11283
glutamate/aspartate:proton symporter; Provisional
 35-473 3.30e-43

glutamate/aspartate:proton symporter; Provisional


Pssm-ID: 183075 [Multi-domain]  Cd Length: 437  Bit Score: 159.16  E-value: 3.30e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688618000  35 KNLLLTLT---VMGVIMGAVSGMLLRVASPIDDNIVMVIAFP-GDILMRMLKMLILPLIISSLITGLAGL-DAKSSGRLG 109
Cdd:PRK11283   2 KNIKFSLAwqiLIALVLGILLGAYLHYHSDSRDWLVSNLLSPaGDIFIHLIKMIVVPIVISTLIVGIAGVgDAKQLGRIG 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688618000 110 SRAMIYYMTTTVIAAVLGVILVLLIHPGNpklkenlgeGLENDEVSSLDAffdlirnlfpeNLVQACFQQIQTvvkkvev 189
Cdd:PRK11283  82 AKTIIYFEVITTVAIILGITLANVFQPGA---------GIDMSQLATVDI-----------SKYQSTTEEVQS------- 134

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688618000 190 qpdldDTNSTMSEYLSnaTKPPPIFkdkkSLQFKSGMnvLGLIGFFIAFGICMGKMGEKARL-MIDFFNILNEIVMKLVI 268
Cdd:PRK11283 135 -----HSHGLMGTILS--LIPTNIF----ASMAKGEM--LPIIFFSVLFGLGLSSLPATHREpLVTVFRSVSETMFKVTH 201

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688618000 269 MIMWYSPFGIACLIcgkiisikdlEVVARQLGMYMITVIVGLII--HGAIFlpciYFAIV------RKNPFSFF--MGIF 338
Cdd:PRK11283 202 MVMRYAPVGVFALI----------AVTVANFGFASLWPLAKLVLlvYFAIL----FFALVvlgivaRLCGLSIWilIRIL 267

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688618000 339 Q-AWITALGTASSAGTLPvtfRCLE--ENLGIDKRVTRFVLPVGATINMDGTALYEAVAAIFIAQMNGIDLDPGQIVTVS 415
Cdd:PRK11283 268 KdELILAYSTASSETVLP---RIIEkmEAYGAPKSITSFVVPTGYSFNLDGSTLYQSIAAIFIAQLYGIDLSIWQEIILV 344

                        410       420       430       440       450
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 688618000 416 LTATLASVGAASIPSAGLVTMLLILTAVGLPTQDISLLVAVDWLLDRFRTSVNVVGDS 473
Cdd:PRK11283 345 LTLMVTSKGIAGVPGVSFVVLLATLGSVGIPLEGLAFIAGVDRILDMARTALNVVGNA 402
PRK13027 PRK13027
C4-dicarboxylate transporter DctA; Reviewed
 74-472 8.42e-36

C4-dicarboxylate transporter DctA; Reviewed


Pssm-ID: 183850 [Multi-domain]  Cd Length: 421  Bit Score: 138.26  E-value: 8.42e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688618000  74 GDILMRMLKMLILPLIISSLITGLAGL-DAKSSGRLGSRAMIYYMTTTVIAAVLGVILVLLIHPGNpklkenlgeGLeND 152
Cdd:PRK13027  37 GDGFIKLIKMLIGPIVFCVVVSGIAGAgDLKKVGRVGLKAVIYFEVMTTIALVIGLVLAYLTGPGV---------GM-NI 106

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688618000 153 EVSSLDAffdlirnlfpenlvqacfqqiqtvvkkvevqpdlddtnSTMSEYLSNATK------------PPPIFKdkksl 220
Cdd:PRK13027 107 DLRSLDA--------------------------------------ASLAGYAKNAQSlkgtagfllkliPTTAVD----- 143

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688618000 221 QFKSGmNVLGLIGFFIAFGICMGKMGEKARLMIDFFNILNEIVMKLVIMIMWYSP---FGIACLICGK--IISIKdlevv 295
Cdd:PRK13027 144 AFAKG-DILQVLLFSVLFGSALSLLGERAKRVNRLIDELSHVLFRIMGFIIKLAPlgvLGAIAFTTGKygVGSLK----- 217

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688618000 296 arQLGMYMITVIVGLIIhgaiFLPCIYFAIVRKNPFSFFMGI---FQAWITALGTASSAGTLPVTFRCLEeNLGIDKRVT 372
Cdd:PRK13027 218 --QLGMLVAVFYLTCFV----FVVVVLGAVMRLAGFSVFKLIrylREELLIVLGTASSDAVLPQVMRKLE-HMGIKDSTV 290

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688618000 373 RFVLPVGATINMDGTALYEAVAAIFIAQMNGIDLDPGQIVTVSLTATLASVGAASIPSAGLVTMLLILTAVG-LPTQDIS 451
Cdd:PRK13027 291 GLVIPTGYSFNLDGFSIYLTLAAVFIAQATNTPLSMHDLITILLVSLVTSKGAHGIPGSAIVILAATLSAIPaIPVLGLV 370

                        410       420
                 ....*....|....*....|.
gi 688618000 452 LLVAVDWLLDRFRTSVNVVGD 472
Cdd:PRK13027 371 LILPVDWFMGIARALTNLIGN 391
TcyP COG1823
L-cystine transporter TcyP, sodium:dicarboxylate symporter family [Amino acid transport and ...
 34-479 1.61e-28

L-cystine transporter TcyP, sodium:dicarboxylate symporter family [Amino acid transport and metabolism];


Pssm-ID: 441428  Cd Length: 463  Bit Score: 118.01  E-value: 1.61e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688618000  34 RKNLLLTLTVM-GVIMGAVSGMLLRVASPIDDNIVMV----IAFPGDILMRMLKMLILPLIISSLITGLAGL-DAKSSGR 107
Cdd:COG1823   25 KKHVSFSKRVFtGLGLGILFGLILQLIYGAGSPVIKQsidwFNIVGNGYVRLLQMIVMPLVFVSILSAITKLkNASSLGK 104

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688618000 108 LGSRAMIYYMTTTVIAAVLGVILVLL-------IHPGNPKLKEnlGEGLEN--DEVSSLdAFFDLIRNLFPENlvqacfq 178
Cdd:COG1823  105 ISGLIIGILLGTTAIAALVGILVALLfgltaegLTQGAAETAR--GEALEErlGEVEDL-SLPQQILSFIPTN------- 174

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688618000 179 qiqtvvkkvevqPDLDDTNSTmseylSNATKPPPIFKdkkslqfksgmnvlGLIGffIAFGICMGKMGEKARLMIDFFNI 258
Cdd:COG1823  175 ------------PFADLTGAR-----PTSTIAVVIFA--------------AFLG--IAALGLRRKKPEQAETFLKGIDA 221

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688618000 259 LNEIVMKLVIMIMWYSPFGIACLICgKIISIKDLEVVArQLGMYMITVIVGLIIHGAIFLpcIYFAIVRKNPFSFFMGIF 338
Cdd:COG1823  222 LQAIVMRLVRLVLRLTPYGVLALMT-KVVATSDFADIL-NLGKFVVASYVALIIMFIVHL--LLLALAGLNPLTYFKKVW 297

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688618000 339 QAWITALGTASSAGTLPVTFRCLEENLGIDKRVTRFVLPVGATINMDGTA-LYEAVAAIFIAQMNGID-LDPGQIVTVSL 416
Cdd:COG1823  298 PVLTFAFTSRSSAGTIPLNIETQTKRLGVPEGIANFAASFGATIGQNGCAgIYPAMLAVMIAPTVGINpLDPSFILTLIA 377

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 688618000 417 TATLASVGAASIPSAGLVTMLLILTAVGLPTQDISLLVAVDWLLDRFRTSVNvVGDSYGAGIV 479
Cdd:COG1823  378 VVTISSFGVAGVGGGATFAALIVLSAMGLPVALAGLLISIEPLIDMGRTALN-VSGSMTAGTV 439
PRK14695 PRK14695
serine/threonine transporter SstT; Provisional
 227-454 3.21e-14

serine/threonine transporter SstT; Provisional


Pssm-ID: 173158  Cd Length: 319  Bit Score: 73.55  E-value: 3.21e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688618000 227 NVLGLIGFFIAFGICMGKMGEKARlmiDFFNILNEIVMKLVIMIMWYSPFGIACLICgKIISIKDLEVVArQLGMYMITV 306
Cdd:PRK14695  60 NYIGILSWAVIFGIAMREASKNSK---ELLKTIADVTSKIVEWIINLAPFGILGLVF-KTISDKGVGSLA-NYGILLVLL 134

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688618000 307 IVGLIIHGAIFLPCIYFAIVRKNPFSFFMGIFQ-AWITALGTASSAGTLPVTFRcLEENLGIDKRVTRFVLPVGATINMD 385
Cdd:PRK14695 135 VTTMLFVAPVVNPLIAFFFMRRNPYPLVWNCLRvSGVTAFFTRSSATNIPVNMK-LCHDLGLNPDTYSVSIPLGSTINMA 213

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 688618000 386 GTALYEAVAAIFIAQMNGIDLDPGQIVTVSLTATLASVGAASIPSAGLVTMLLILTAVGLpTQDISLLV 454
Cdd:PRK14695 214 GVAITINLLTLVTVNTLGIPVDFATAFVLSVVAAISACGASGIAGGSLLLIPVACSLFGI-SNDIAIQI 281
SstT COG3633
Na+/serine and Na+/threonine symporter SstT [Amino acid transport and metabolism];
46-445 3.34e-11

Na+/serine and Na+/threonine symporter SstT [Amino acid transport and metabolism];


Pssm-ID: 442850  Cd Length: 406  Bit Score: 65.19  E-value: 3.34e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688618000  46 VIMGAVSGMLLRVASPiddNIVMVIAFPGDILMRMLK----MLILPLIISSLITglagldAKSSGRLGSRAMIY-YMTTT 120
Cdd:COG3633   19 ILIGLVLGILLALLSP---EAAKSVGLLGTLFVGALKavapILVFVLVMSAIAN------HKQGQKTNMKPIIVlYLLGT 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688618000 121 VIAAVLGVI--------LVLLIHPGNPKLKENLGEGLENdevssldaffdLIRNLFpENLVQAcfqqiqtvvkkvevqpd 192
Cdd:COG3633   90 FLAALVAVVasflfpttLTLVAAAADLTPPGGIGEVLKT-----------LLLNVV-DNPVNA----------------- 140

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688618000 193 lddtnstmseyLSNAtkpppifkdkkslqfksgmNVLGLIGFFIAFGICMGKMGEKARLMidfFNILNEIVMKLVIMIMW 272
Cdd:COG3633  141 -----------LANA-------------------NYIGILAWAIGLGLALRHASDTTKTV---LSDLSDAVSKIVRWVIR 187

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688618000 273 YSPFGIACLICGkIISIKDLEVvarqLGMY--MITVIVGLIIHGAIFL-PCIYFAIVRKNPFSF-FMGIFQAWITALGTA 348
Cdd:COG3633  188 FAPLGIFGLVAS-TVATTGFSA----LLGYahLLAVLVGCMLFVALVVnPLIVFLKIRRNPYPLvFTCLRESGITAFFTR 262

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688618000 349 SSAGTLPVTFRcLEENLGIDKRVTRFVLPVGATINMDGtalyeavAAIFIAQMN-------GIDLDPGQIVTVSLTATLA 421
Cdd:COG3633  263 SSAANIPVNMA-LCEKLGLDEDTYSVSIPLGATINMAG-------AAITITVLTlaavhtlGIEVDLPTALLLSVVAAVS 334

                        410       420
                 ....*....|....*....|....
gi 688618000 422 SVGAASIPSAGLvtmLLILTAVGL 445
Cdd:COG3633  335 ACGASGVAGGSL---LLIPLACSL 355
PRK13628 PRK13628
serine/threonine transporter SstT; Provisional
 227-445 2.38e-10

serine/threonine transporter SstT; Provisional


Pssm-ID: 184190 [Multi-domain]  Cd Length: 402  Bit Score: 62.57  E-value: 2.38e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688618000 227 NVLGLIGFFIAFGICMGKMGEKARlmiDFFNILNEIVMKLVIMIMWYSPFGIACLICGkiiSIKDLEVVARQLGMYMITV 306
Cdd:PRK13628 146 NYIGILAWAIGLGLALRHASDTTK---NVVNDLSEAVSQIVKWVIRFAPIGIFGLVAS---TLAETGFSALAGYAQLLAV 219

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688618000 307 IVGLIIHGA-IFLPCIYFAIVRKNPFSF-FMGIFQAWITALGTASSAGTLPVTFRcLEENLGIDKRVTRFVLPVGATINM 384
Cdd:PRK13628 220 LVGCMLFVAlVVNPLIVFWKIRRNPYPLvFTCLRESGVTAFFTRSSAANIPVNMA-LCEKLGLDEDTYSVSIPLGATINM 298

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 688618000 385 DGTALYEAVAAIFIAQMNGIDLDPGQIVTVSLTATLASVGAASIPSAGLvtmLLILTAVGL 445
Cdd:PRK13628 299 AGAAITITVLTLAAVHTLGIPVDLPTALLLSVVAAISACGASGVAGGSL---LLIPLACSL 356
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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