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Conserved domains on  [gi|688555229|ref|XP_009299808|]
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armadillo repeat protein deleted in velo-cardio-facial syndrome isoform X16 [Danio rerio]

Protein Classification

armadillo/beta-catenin-like repeat-containing protein( domain architecture ID 12192474)

armadillo/beta-catenin-like repeat-containing protein similar to catenin delta and plakophilin

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ARM smart00185
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form ...
 358-398 4.76e-09

Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form superhelix of helices that is proposed to mediate interaction of beta-catenin with its ligands. Involved in transducing the Wingless/Wnt signal. In plakoglobin arm repeats bind alpha-catenin and N-cadherin.


:

Pssm-ID: 214547 [Multi-domain]  Cd Length: 41  Bit Score: 52.43  E-value: 4.76e-09
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|.
gi 688555229   358 NDKIKKDVRQLKGIPVLVSLLDHPKAEVHRKACGALRNISY 398
Cdd:smart00185   1 DDENKQAVVDAGGLPALVELLKSEDEEVVKEAAWALSNLSS 41
ARM smart00185
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form ...
 677-716 1.68e-08

Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form superhelix of helices that is proposed to mediate interaction of beta-catenin with its ligands. Involved in transducing the Wingless/Wnt signal. In plakoglobin arm repeats bind alpha-catenin and N-cadherin.


:

Pssm-ID: 214547 [Multi-domain]  Cd Length: 41  Bit Score: 50.89  E-value: 1.68e-08
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 688555229   677 SNYIRATVRKEKGLPILVELLRSDSDKVVRAVAIALRNLS 716
Cdd:smart00185   1 DDENKQAVVDAGGLPALVELLKSEDEEVVKEAAWALSNLS 40
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
 401-442 3.38e-06

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


:

Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 44.37  E-value: 3.38e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 688555229  401 DHDNKVAIKSCDGIPALIRLLrKTNDMEVRELITGTLWNLSS 442
Cdd:pfam00514   1 SPENKQAVIEAGAVPPLVRLL-SSPDEEVQEEAAWALSNLAA 41
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
 635-671 4.61e-03

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


:

Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 35.89  E-value: 4.61e-03
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 688555229  635 ELLYQPEVVRLYLSLLTeSQNYNTLEAAAGALQNLSA 671
Cdd:pfam00514   6 QAVIEAGAVPPLVRLLS-SPDEEVQEEAAWALSNLAA 41
 
Name Accession Description Interval E-value
ARM smart00185
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form ...
 358-398 4.76e-09

Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form superhelix of helices that is proposed to mediate interaction of beta-catenin with its ligands. Involved in transducing the Wingless/Wnt signal. In plakoglobin arm repeats bind alpha-catenin and N-cadherin.


Pssm-ID: 214547 [Multi-domain]  Cd Length: 41  Bit Score: 52.43  E-value: 4.76e-09
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|.
gi 688555229   358 NDKIKKDVRQLKGIPVLVSLLDHPKAEVHRKACGALRNISY 398
Cdd:smart00185   1 DDENKQAVVDAGGLPALVELLKSEDEEVVKEAAWALSNLSS 41
ARM smart00185
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form ...
 677-716 1.68e-08

Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form superhelix of helices that is proposed to mediate interaction of beta-catenin with its ligands. Involved in transducing the Wingless/Wnt signal. In plakoglobin arm repeats bind alpha-catenin and N-cadherin.


Pssm-ID: 214547 [Multi-domain]  Cd Length: 41  Bit Score: 50.89  E-value: 1.68e-08
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 688555229   677 SNYIRATVRKEKGLPILVELLRSDSDKVVRAVAIALRNLS 716
Cdd:smart00185   1 DDENKQAVVDAGGLPALVELLKSEDEEVVKEAAWALSNLS 40
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
 358-397 2.01e-08

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 50.92  E-value: 2.01e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 688555229  358 NDKIKKDVRQLKGIPVLVSLLDHPKAEVHRKACGALRNIS 397
Cdd:pfam00514   1 SPENKQAVIEAGAVPPLVRLLSSPDEEVQEEAAWALSNLA 40
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
 401-442 3.38e-06

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 44.37  E-value: 3.38e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 688555229  401 DHDNKVAIKSCDGIPALIRLLrKTNDMEVRELITGTLWNLSS 442
Cdd:pfam00514   1 SPENKQAVIEAGAVPPLVRLL-SSPDEEVQEEAAWALSNLAA 41
PLN03200 PLN03200
cellulose synthase-interactive protein; Provisional
 329-442 1.42e-05

cellulose synthase-interactive protein; Provisional


Pssm-ID: 215629 [Multi-domain]  Cd Length: 2102  Bit Score: 49.33  E-value: 1.42e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688555229  329 LPEVIAMLGHPIDPVKSNAAAYLQHLCYENDkikKDVRQLKG--IPVLVSLLDHPKAEVHRKACGALRNISYG--KDHdn 404
Cdd:PLN03200   60 MPLLVSLLRSGTLGAKVNAAAVLGVLCKEED---LRVKVLLGgcIPPLLSLLKSGSAEAQKAAAEAIYAVSSGglSDH-- 134

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 688555229  405 kVAIK--SCDGI-PALIRLLRKTN--DMEVRELITGTLWNLSS 442
Cdd:PLN03200  135 -VGSKifSTEGVvPSLWDQLQPGNkqDKVVEGLLTGALRNLCG 176
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
 677-716 2.39e-05

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 42.06  E-value: 2.39e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 688555229  677 SNYIRATVRKEKGLPILVELLRSDSDKVVRAVAIALRNLS 716
Cdd:pfam00514   1 SPENKQAVIEAGAVPPLVRLLSSPDEEVQEEAAWALSNLA 40
ARM smart00185
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form ...
 401-442 3.53e-05

Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form superhelix of helices that is proposed to mediate interaction of beta-catenin with its ligands. Involved in transducing the Wingless/Wnt signal. In plakoglobin arm repeats bind alpha-catenin and N-cadherin.


Pssm-ID: 214547 [Multi-domain]  Cd Length: 41  Bit Score: 41.65  E-value: 3.53e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 688555229   401 DHDNKVAIKSCDGIPALIRLLRKTNDmEVRELITGTLWNLSS 442
Cdd:smart00185   1 DDENKQAVVDAGGLPALVELLKSEDE-EVVKEAAWALSNLSS 41
HEAT COG1413
HEAT repeat [General function prediction only];
323-440 1.37e-03

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 40.00  E-value: 1.37e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688555229 323 RWRDPD-LPEVIAMLGHPIDPVKSNAAAYLqhlcyendkikKDVRQLKGIPVLVSLLDHPKAEVHRKACGALRNisygkd 401
Cdd:COG1413   42 RLGDPRaVPALLEALKDPDPEVRAAAAEAL-----------GRIGDPEAVPALIAALKDEDPEVRRAAAEALGR------ 104

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 688555229 402 hdnkvaIKSCDGIPALIRLLrKTNDMEVRELITGTLWNL 440
Cdd:COG1413  105 ------LGDPAAVPALLEAL-KDPDWEVRRAAARALGRL 136
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
 635-671 4.61e-03

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 35.89  E-value: 4.61e-03
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 688555229  635 ELLYQPEVVRLYLSLLTeSQNYNTLEAAAGALQNLSA 671
Cdd:pfam00514   6 QAVIEAGAVPPLVRLLS-SPDEEVQEEAAWALSNLAA 41
 
Name Accession Description Interval E-value
ARM smart00185
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form ...
 358-398 4.76e-09

Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form superhelix of helices that is proposed to mediate interaction of beta-catenin with its ligands. Involved in transducing the Wingless/Wnt signal. In plakoglobin arm repeats bind alpha-catenin and N-cadherin.


Pssm-ID: 214547 [Multi-domain]  Cd Length: 41  Bit Score: 52.43  E-value: 4.76e-09
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|.
gi 688555229   358 NDKIKKDVRQLKGIPVLVSLLDHPKAEVHRKACGALRNISY 398
Cdd:smart00185   1 DDENKQAVVDAGGLPALVELLKSEDEEVVKEAAWALSNLSS 41
ARM smart00185
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form ...
 677-716 1.68e-08

Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form superhelix of helices that is proposed to mediate interaction of beta-catenin with its ligands. Involved in transducing the Wingless/Wnt signal. In plakoglobin arm repeats bind alpha-catenin and N-cadherin.


Pssm-ID: 214547 [Multi-domain]  Cd Length: 41  Bit Score: 50.89  E-value: 1.68e-08
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|
gi 688555229   677 SNYIRATVRKEKGLPILVELLRSDSDKVVRAVAIALRNLS 716
Cdd:smart00185   1 DDENKQAVVDAGGLPALVELLKSEDEEVVKEAAWALSNLS 40
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
 358-397 2.01e-08

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 50.92  E-value: 2.01e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 688555229  358 NDKIKKDVRQLKGIPVLVSLLDHPKAEVHRKACGALRNIS 397
Cdd:pfam00514   1 SPENKQAVIEAGAVPPLVRLLSSPDEEVQEEAAWALSNLA 40
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
 401-442 3.38e-06

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 44.37  E-value: 3.38e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 688555229  401 DHDNKVAIKSCDGIPALIRLLrKTNDMEVRELITGTLWNLSS 442
Cdd:pfam00514   1 SPENKQAVIEAGAVPPLVRLL-SSPDEEVQEEAAWALSNLAA 41
PLN03200 PLN03200
cellulose synthase-interactive protein; Provisional
 329-442 1.42e-05

cellulose synthase-interactive protein; Provisional


Pssm-ID: 215629 [Multi-domain]  Cd Length: 2102  Bit Score: 49.33  E-value: 1.42e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688555229  329 LPEVIAMLGHPIDPVKSNAAAYLQHLCYENDkikKDVRQLKG--IPVLVSLLDHPKAEVHRKACGALRNISYG--KDHdn 404
Cdd:PLN03200   60 MPLLVSLLRSGTLGAKVNAAAVLGVLCKEED---LRVKVLLGgcIPPLLSLLKSGSAEAQKAAAEAIYAVSSGglSDH-- 134

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 688555229  405 kVAIK--SCDGI-PALIRLLRKTN--DMEVRELITGTLWNLSS 442
Cdd:PLN03200  135 -VGSKifSTEGVvPSLWDQLQPGNkqDKVVEGLLTGALRNLCG 176
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
 677-716 2.39e-05

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 42.06  E-value: 2.39e-05
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 688555229  677 SNYIRATVRKEKGLPILVELLRSDSDKVVRAVAIALRNLS 716
Cdd:pfam00514   1 SPENKQAVIEAGAVPPLVRLLSSPDEEVQEEAAWALSNLA 40
ARM smart00185
Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form ...
 401-442 3.53e-05

Armadillo/beta-catenin-like repeats; Approx. 40 amino acid repeat. Tandem repeats form superhelix of helices that is proposed to mediate interaction of beta-catenin with its ligands. Involved in transducing the Wingless/Wnt signal. In plakoglobin arm repeats bind alpha-catenin and N-cadherin.


Pssm-ID: 214547 [Multi-domain]  Cd Length: 41  Bit Score: 41.65  E-value: 3.53e-05
                           10        20        30        40
                   ....*....|....*....|....*....|....*....|..
gi 688555229   401 DHDNKVAIKSCDGIPALIRLLRKTNDmEVRELITGTLWNLSS 442
Cdd:smart00185   1 DDENKQAVVDAGGLPALVELLKSEDE-EVVKEAAWALSNLSS 41
HEAT_2 pfam13646
HEAT repeats; This family includes multiple HEAT repeats.
 640-713 1.36e-03

HEAT repeats; This family includes multiple HEAT repeats.


Pssm-ID: 433376 [Multi-domain]  Cd Length: 88  Bit Score: 38.47  E-value: 1.36e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 688555229  640 PEVVRLYLSLLtESQNYNTLEAAAGALqnlsagqwtwsnyirATVRKEKGLPILVELLRSDSDKVVRAVAI-ALR 713
Cdd:pfam13646  30 PEAVPALLELL-KDEDPAVRRAAAEAL---------------GKIGDPEALPALLELLRDDDDDVVRAAAAeALA 88
HEAT COG1413
HEAT repeat [General function prediction only];
323-440 1.37e-03

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 40.00  E-value: 1.37e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 688555229 323 RWRDPD-LPEVIAMLGHPIDPVKSNAAAYLqhlcyendkikKDVRQLKGIPVLVSLLDHPKAEVHRKACGALRNisygkd 401
Cdd:COG1413   42 RLGDPRaVPALLEALKDPDPEVRAAAAEAL-----------GRIGDPEAVPALIAALKDEDPEVRRAAAEALGR------ 104

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 688555229 402 hdnkvaIKSCDGIPALIRLLrKTNDMEVRELITGTLWNL 440
Cdd:COG1413  105 ------LGDPAAVPALLEAL-KDPDWEVRRAAARALGRL 136
Arm pfam00514
Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form ...
 635-671 4.61e-03

Armadillo/beta-catenin-like repeat; Approx. 40 amino acid repeat. Tandem repeats form super-helix of helices that is proposed to mediate interaction of beta-catenin with its ligands. CAUTION: This family does not contain all known armadillo repeats.


Pssm-ID: 425727 [Multi-domain]  Cd Length: 41  Bit Score: 35.89  E-value: 4.61e-03
                          10        20        30
                  ....*....|....*....|....*....|....*..
gi 688555229  635 ELLYQPEVVRLYLSLLTeSQNYNTLEAAAGALQNLSA 671
Cdd:pfam00514   6 QAVIEAGAVPPLVRLLS-SPDEEVQEEAAWALSNLAA 41
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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