|
Name |
Accession |
Description |
Interval |
E-value |
| TLE_N |
pfam03920 |
Groucho/TLE N-terminal Q-rich domain; The N-terminal domain of the Grouch/TLE co-repressor ... |
17-152 |
2.15e-80 |
|
Groucho/TLE N-terminal Q-rich domain; The N-terminal domain of the Grouch/TLE co-repressor proteins are involved in oligomerization.
Pssm-ID: 461094 Cd Length: 117 Bit Score: 253.89 E-value: 2.15e-80
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534474 17 FKFSVLEICDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHYVMaaphqcpqggtsyphwprlsplqYYEMSYGLNIE 96
Cdd:pfam03920 1 FKFTVPETCDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHYVM-----------------------YYEMSYGLNIE 57
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 755534474 97 MHKQAEIVKRLSAICAQMVPFLTQEHQQQVLQAVDRAKQVTVGELNSLLGQQNQLQ 152
Cdd:pfam03920 58 MHKQTEIAKRLNAICAQVIPFLSQEHQQQVAQAVERAKQVTMAELNAIIGQQQQLQ 113
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
473-725 |
5.16e-36 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 141.20 E-value: 5.16e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534474 473 RQLHTL-AHGEVVCAVTISSSTQHVYTGGK-GCVKVWDVGqpgSKTPVAQLDclNRDNYIRSCKLLPDGQSLIVGGEAST 550
Cdd:COG2319 153 KLLRTLtGHSGAVTSVAFSPDGKLLASGSDdGTVRLWDLA---TGKLLRTLT--GHTGAVRSVAFSPDGKLLASGSADGT 227
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534474 551 LSIWDLAapTPRIKAELTSSAPACYALAVSPDAKVCFSCCSDGNIVVWDLQNQAMVRQFQGHTDGASCIDISDYGTRLWT 630
Cdd:COG2319 228 VRLWDLA--TGKLLRTLTGHSGSVRSVAFSPDGRLLASGSADGTVRLWDLATGELLRTLTGHSGGVNSVAFSPDGKLLAS 305
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534474 631 GGLDNTVRCWDLREGRQLQQHD-FSSQIFSLGHCPNQDWLAVGMESSHVEVLHVR-KPEKYQLRLHESCVLSLKFASCGR 708
Cdd:COG2319 306 GSDDGTVRLWDLATGKLLRTLTgHTGAVRSVAFSPDGKTLASGSDDGTVRLWDLAtGELLRTLTGHTGAVTSVAFSPDGR 385
|
250
....*....|....*..
gi 755534474 709 WFVSTGKDNLLNAWRTP 725
Cdd:COG2319 386 TLASGSADGTVRLWDLA 402
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
466-723 |
2.20e-33 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 130.15 E-value: 2.20e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534474 466 TGIPRHARQLHTlahGEVVCAVTISSSTQhVYTGGK-GCVKVWDVGQPgsktpvaqlDCLNR----DNYIRSCKLLPDGQ 540
Cdd:cd00200 40 TGELLRTLKGHT---GPVRDVAASADGTY-LASGSSdKTIRLWDLETG---------ECVRTltghTSYVSSVAFSPDGR 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534474 541 SLIVGGEASTLSIWDLaaPTPRIKAELTSSAPACYALAVSPDAKVCFSCCSDGNIVVWDLQNQAMVRQFQGHTDGASCID 620
Cdd:cd00200 107 ILSSSSRDKTIKVWDV--ETGKCLTTLRGHTDWVNSVAFSPDGTFVASSSQDGTIKLWDLRTGKCVATLTGHTGEVNSVA 184
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534474 621 ISDYGTRLWTGGLDNTVRCWDLREGRQLQQHD-FSSQIFSLGHCPNQDWLAVGMESSHVEVLHVRKPE-KYQLRLHESCV 698
Cdd:cd00200 185 FSPDGEKLLSSSSDGTIKLWDLSTGKCLGTLRgHENGVNSVAFSPDGYLLASGSEDGTIRVWDLRTGEcVQTLSGHTNSV 264
|
250 260
....*....|....*....|....*
gi 755534474 699 LSLKFASCGRWFVSTGKDNLLNAWR 723
Cdd:cd00200 265 TSLAWSPDGKRLASGSADGTIRIWD 289
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
606-641 |
9.61e-07 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 46.15 E-value: 9.61e-07
10 20 30
....*....|....*....|....*....|....*.
gi 755534474 606 VRQFQGHTDGASCIDISDYGTRLWTGGLDNTVRCWD 641
Cdd:smart00320 5 LKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
269-459 |
1.67e-06 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 52.25 E-value: 1.67e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534474 269 PSEPPSPVT--TPCGKAPLCIPARRDLTDSPASLASSLGSPLPRSKDIALNDLPTGTPASRSCGTSPPQDSSTPGPSSAS 346
Cdd:PHA03247 2739 PAPPAVPAGpaTPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAAL 2818
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534474 347 HLCQLAAQPAAPTDSIALRSPLTLSSPFTSSFSLGSHSTLNGDLSMPGSyvglhlspqvsssvvYGRSPLQMAFESHPHL 426
Cdd:PHA03247 2819 PPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRPP---------------SRSPAAKPAAPARPPV 2883
|
170 180 190
....*....|....*....|....*....|...
gi 755534474 427 RgssvSLPGIPVAKPAYSFHVSADGQmQPVPFP 459
Cdd:PHA03247 2884 R----RLARPAVSRSTESFALPPDQP-ERPPQP 2911
|
|
| WD40 |
pfam00400 |
WD domain, G-beta repeat; |
606-641 |
1.29e-05 |
|
WD domain, G-beta repeat;
Pssm-ID: 459801 [Multi-domain] Cd Length: 39 Bit Score: 42.72 E-value: 1.29e-05
10 20 30
....*....|....*....|....*....|....*.
gi 755534474 606 VRQFQGHTDGASCIDISDYGTRLWTGGLDNTVRCWD 641
Cdd:pfam00400 4 LKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
|
|
|
|
Name |
Accession |
Description |
Interval |
E-value |
| TLE_N |
pfam03920 |
Groucho/TLE N-terminal Q-rich domain; The N-terminal domain of the Grouch/TLE co-repressor ... |
17-152 |
2.15e-80 |
|
Groucho/TLE N-terminal Q-rich domain; The N-terminal domain of the Grouch/TLE co-repressor proteins are involved in oligomerization.
Pssm-ID: 461094 Cd Length: 117 Bit Score: 253.89 E-value: 2.15e-80
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534474 17 FKFSVLEICDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHYVMaaphqcpqggtsyphwprlsplqYYEMSYGLNIE 96
Cdd:pfam03920 1 FKFTVPETCDRIKEEFQFLQAQYHSLKLECEKLASEKTEMQRHYVM-----------------------YYEMSYGLNIE 57
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 755534474 97 MHKQAEIVKRLSAICAQMVPFLTQEHQQQVLQAVDRAKQVTVGELNSLLGQQNQLQ 152
Cdd:pfam03920 58 MHKQTEIAKRLNAICAQVIPFLSQEHQQQVAQAVERAKQVTMAELNAIIGQQQQLQ 113
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
473-725 |
5.16e-36 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 141.20 E-value: 5.16e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534474 473 RQLHTL-AHGEVVCAVTISSSTQHVYTGGK-GCVKVWDVGqpgSKTPVAQLDclNRDNYIRSCKLLPDGQSLIVGGEAST 550
Cdd:COG2319 153 KLLRTLtGHSGAVTSVAFSPDGKLLASGSDdGTVRLWDLA---TGKLLRTLT--GHTGAVRSVAFSPDGKLLASGSADGT 227
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534474 551 LSIWDLAapTPRIKAELTSSAPACYALAVSPDAKVCFSCCSDGNIVVWDLQNQAMVRQFQGHTDGASCIDISDYGTRLWT 630
Cdd:COG2319 228 VRLWDLA--TGKLLRTLTGHSGSVRSVAFSPDGRLLASGSADGTVRLWDLATGELLRTLTGHSGGVNSVAFSPDGKLLAS 305
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534474 631 GGLDNTVRCWDLREGRQLQQHD-FSSQIFSLGHCPNQDWLAVGMESSHVEVLHVR-KPEKYQLRLHESCVLSLKFASCGR 708
Cdd:COG2319 306 GSDDGTVRLWDLATGKLLRTLTgHTGAVRSVAFSPDGKTLASGSDDGTVRLWDLAtGELLRTLTGHTGAVTSVAFSPDGR 385
|
250
....*....|....*..
gi 755534474 709 WFVSTGKDNLLNAWRTP 725
Cdd:COG2319 386 TLASGSADGTVRLWDLA 402
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
426-727 |
4.18e-35 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 138.51 E-value: 4.18e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534474 426 LRGSSVSLPGIPVAKPAYSFHVSADGQMQPVPFPSDALVGTGIPRHARQLHTLAHGEVVCAVTISSSTQHVYTGGK-GCV 504
Cdd:COG2319 65 AAAGALLATLLGHTAAVLSVAFSPDGRLLASASADGTVRLWDLATGLLLRTLTGHTGAVRSVAFSPDGKTLASGSAdGTV 144
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534474 505 KVWDVGqpgSKTPVAQLDclNRDNYIRSCKLLPDGQSLIVGGEASTLSIWDLAapTPRIKAELTSSAPACYALAVSPDAK 584
Cdd:COG2319 145 RLWDLA---TGKLLRTLT--GHSGAVTSVAFSPDGKLLASGSDDGTVRLWDLA--TGKLLRTLTGHTGAVRSVAFSPDGK 217
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534474 585 VCFSCCSDGNIVVWDLQNQAMVRQFQGHTDGASCIDISDYGTRLWTGGLDNTVRCWDLREGRQLQQ-HDFSSQIFSLGHC 663
Cdd:COG2319 218 LLASGSADGTVRLWDLATGKLLRTLTGHSGSVRSVAFSPDGRLLASGSADGTVRLWDLATGELLRTlTGHSGGVNSVAFS 297
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 755534474 664 PNQDWLAVGMESSHVEVLHVRKPEK-YQLRLHESCVLSLKFASCGRWFVSTGKDNLLNAWRTPYG 727
Cdd:COG2319 298 PDGKLLASGSDDGTVRLWDLATGKLlRTLTGHTGAVRSVAFSPDGKTLASGSDDGTVRLWDLATG 362
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
466-723 |
2.20e-33 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 130.15 E-value: 2.20e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534474 466 TGIPRHARQLHTlahGEVVCAVTISSSTQhVYTGGK-GCVKVWDVGQPgsktpvaqlDCLNR----DNYIRSCKLLPDGQ 540
Cdd:cd00200 40 TGELLRTLKGHT---GPVRDVAASADGTY-LASGSSdKTIRLWDLETG---------ECVRTltghTSYVSSVAFSPDGR 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534474 541 SLIVGGEASTLSIWDLaaPTPRIKAELTSSAPACYALAVSPDAKVCFSCCSDGNIVVWDLQNQAMVRQFQGHTDGASCID 620
Cdd:cd00200 107 ILSSSSRDKTIKVWDV--ETGKCLTTLRGHTDWVNSVAFSPDGTFVASSSQDGTIKLWDLRTGKCVATLTGHTGEVNSVA 184
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534474 621 ISDYGTRLWTGGLDNTVRCWDLREGRQLQQHD-FSSQIFSLGHCPNQDWLAVGMESSHVEVLHVRKPE-KYQLRLHESCV 698
Cdd:cd00200 185 FSPDGEKLLSSSSDGTIKLWDLSTGKCLGTLRgHENGVNSVAFSPDGYLLASGSEDGTIRVWDLRTGEcVQTLSGHTNSV 264
|
250 260
....*....|....*....|....*
gi 755534474 699 LSLKFASCGRWFVSTGKDNLLNAWR 723
Cdd:cd00200 265 TSLAWSPDGKRLASGSADGTIRIWD 289
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
426-734 |
3.26e-32 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 130.03 E-value: 3.26e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534474 426 LRGSSVSLPGIPVAKPAYSFHVSADGQMQPVPFPSDALVGTGIPRHARQLHTLAHGEVVCAVTISSSTQHVYTGGK-GCV 504
Cdd:COG2319 23 AALGALLLLLLGLAAAVASLAASPDGARLAAGAGDLTLLLLDAAAGALLATLLGHTAAVLSVAFSPDGRLLASASAdGTV 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534474 505 KVWDVgqpgsKTPVAQLDCLNRDNYIRSCKLLPDGQSLIVGGEASTLSIWDLAapTPRIKAELTSSAPACYALAVSPDAK 584
Cdd:COG2319 103 RLWDL-----ATGLLLRTLTGHTGAVRSVAFSPDGKTLASGSADGTVRLWDLA--TGKLLRTLTGHSGAVTSVAFSPDGK 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534474 585 VCFSCCSDGNIVVWDLQNQAMVRQFQGHTDGASCIDISDYGTRLWTGGLDNTVRCWDLREGRQLQQ-HDFSSQIFSLGHC 663
Cdd:COG2319 176 LLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKLLASGSADGTVRLWDLATGKLLRTlTGHSGSVRSVAFS 255
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 755534474 664 PNQDWLAVGMESSHVEVLHVR-KPEKYQLRLHESCVLSLKFASCGRWFVSTGKDNLLNAWRTPYGASIFQVT 734
Cdd:COG2319 256 PDGRLLASGSADGTVRLWDLAtGELLRTLTGHSGGVNSVAFSPDGKLLASGSDDGTVRLWDLATGKLLRTLT 327
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
480-724 |
3.25e-31 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 123.98 E-value: 3.25e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534474 480 HGEVVCAVTISSSTQHVYTGGK-GCVKVWDV-GQPGSKTPVAQLDClnrdnyIRSCKLLPDGQSLIVGGEASTLSIWDLa 557
Cdd:cd00200 8 HTGGVTCVAFSPDGKLLATGSGdGTIKVWDLeTGELLRTLKGHTGP------VRDVAASADGTYLASGSSDKTIRLWDL- 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534474 558 aPTPRIKAELTSSAPACYALAVSPDAKVCFSCCSDGNIVVWDLQNQAMVRQFQGHTDGASCIDISDYGTRLWTGGLDNTV 637
Cdd:cd00200 81 -ETGECVRTLTGHTSYVSSVAFSPDGRILSSSSRDKTIKVWDVETGKCLTTLRGHTDWVNSVAFSPDGTFVASSSQDGTI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534474 638 RCWDLREGR---QLQQHDfsSQIFSLGHCPNQDWLAVGMESSHVEVLHVRKPE-KYQLRLHESCVLSLKFASCGRWFVST 713
Cdd:cd00200 160 KLWDLRTGKcvaTLTGHT--GEVNSVAFSPDGEKLLSSSSDGTIKLWDLSTGKcLGTLRGHENGVNSVAFSPDGYLLASG 237
|
250
....*....|.
gi 755534474 714 GKDNLLNAWRT 724
Cdd:cd00200 238 SEDGTIRVWDL 248
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
473-602 |
2.37e-12 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 69.55 E-value: 2.37e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534474 473 RQLHTLA-HGEVVCAVTISSSTQHVYTGGKGC-VKVWDVGqpgSKTPVAQLDclNRDNYIRSCKLLPDGQSLIVGGEAST 550
Cdd:COG2319 279 ELLRTLTgHSGGVNSVAFSPDGKLLASGSDDGtVRLWDLA---TGKLLRTLT--GHTGAVRSVAFSPDGKTLASGSDDGT 353
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|..
gi 755534474 551 LSIWDLAapTPRIKAELTSSAPACYALAVSPDAKVCFSCCSDGNIVVWDLQN 602
Cdd:COG2319 354 VRLWDLA--TGELLRTLTGHTGAVTSVAFSPDGRTLASGSADGTVRLWDLAT 403
|
|
| WD40 |
cd00200 |
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ... |
605-727 |
5.12e-11 |
|
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.
Pssm-ID: 238121 [Multi-domain] Cd Length: 289 Bit Score: 64.28 E-value: 5.12e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534474 605 MVRQFQGHTDGASCIDISDYGTRLWTGGLDNTVRCWDLREG---RQLQQHdfSSQIFSLGHCPNQDWLAVGMESSHVEVL 681
Cdd:cd00200 1 LRRTLKGHTGGVTCVAFSPDGKLLATGSGDGTIKVWDLETGellRTLKGH--TGPVRDVAASADGTYLASGSSDKTIRLW 78
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 755534474 682 HVRKPEK-YQLRLHESCVLSLKFASCGRWFVSTGKDNLLNAWRTPYG 727
Cdd:cd00200 79 DLETGECvRTLTGHTSYVSSVAFSPDGRILSSSSRDKTIKVWDVETG 125
|
|
| WD40 |
COG2319 |
WD40 repeat [General function prediction only]; |
535-734 |
6.22e-11 |
|
WD40 repeat [General function prediction only];
Pssm-ID: 441893 [Multi-domain] Cd Length: 403 Bit Score: 65.32 E-value: 6.22e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534474 535 LLPDGQSLIVGGEASTLSIWDLAAPTPRIKAELTSSAPAcyALAVSPDAKVCFSCCSDGNIVVWDLQNQAMVRQFQGHTD 614
Cdd:COG2319 2 LSADGAALAAASADLALALLAAALGALLLLLLGLAAAVA--SLAASPDGARLAAGAGDLTLLLLDAAAGALLATLLGHTA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534474 615 GASCIDISDYGTRLWTGGLDNTVRCWDLREGRQLQQ-HDFSSQIFSLGHCPNQDWLAVGMESSHVEVLHVRKPEK-YQLR 692
Cdd:COG2319 80 AVLSVAFSPDGRLLASASADGTVRLWDLATGLLLRTlTGHTGAVRSVAFSPDGKTLASGSADGTVRLWDLATGKLlRTLT 159
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 755534474 693 LHESCVLSLKFASCGRWFVSTGKDNLLNAWRTPYGASIFQVT 734
Cdd:COG2319 160 GHSGAVTSVAFSPDGKLLASGSDDGTVRLWDLATGKLLRTLT 201
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
606-641 |
9.61e-07 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 46.15 E-value: 9.61e-07
10 20 30
....*....|....*....|....*....|....*.
gi 755534474 606 VRQFQGHTDGASCIDISDYGTRLWTGGLDNTVRCWD 641
Cdd:smart00320 5 LKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
269-459 |
1.67e-06 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 52.25 E-value: 1.67e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534474 269 PSEPPSPVT--TPCGKAPLCIPARRDLTDSPASLASSLGSPLPRSKDIALNDLPTGTPASRSCGTSPPQDSSTPGPSSAS 346
Cdd:PHA03247 2739 PAPPAVPAGpaTPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAAL 2818
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534474 347 HLCQLAAQPAAPTDSIALRSPLTLSSPFTSSFSLGSHSTLNGDLSMPGSyvglhlspqvsssvvYGRSPLQMAFESHPHL 426
Cdd:PHA03247 2819 PPAASPAGPLPPPTSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRPP---------------SRSPAAKPAAPARPPV 2883
|
170 180 190
....*....|....*....|....*....|...
gi 755534474 427 RgssvSLPGIPVAKPAYSFHVSADGQmQPVPFP 459
Cdd:PHA03247 2884 R----RLARPAVSRSTESFALPPDQP-ERPPQP 2911
|
|
| WD40 |
pfam00400 |
WD domain, G-beta repeat; |
606-641 |
1.29e-05 |
|
WD domain, G-beta repeat;
Pssm-ID: 459801 [Multi-domain] Cd Length: 39 Bit Score: 42.72 E-value: 1.29e-05
10 20 30
....*....|....*....|....*....|....*.
gi 755534474 606 VRQFQGHTDGASCIDISDYGTRLWTGGLDNTVRCWD 641
Cdd:pfam00400 4 LKTLEGHTGSVTSLAFSPDGKLLASGSDDGTVKVWD 39
|
|
| YncE |
COG3391 |
DNA-binding beta-propeller fold protein YncE [General function prediction only]; |
535-642 |
1.42e-03 |
|
DNA-binding beta-propeller fold protein YncE [General function prediction only];
Pssm-ID: 442618 [Multi-domain] Cd Length: 237 Bit Score: 41.22 E-value: 1.42e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 755534474 535 LLPDGQSLIVGGEAS-TLSIWDLAapTPRIKAEL-TSSAPacYALAVSPDAKVCFSCCSDGN-----IVVWDLQNQAMVR 607
Cdd:COG3391 117 VDPDGGRLYVADSGNgRVSVIDTA--TGKVVATIpVGAGP--HGIAVDPDGKRLYVANSGSNtvsviVSVIDTATGKVVA 192
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 755534474 608 QFQGHtDGASCIDISDYGTRLW--------TGGLDNTVRCWDL 642
Cdd:COG3391 193 TIPVG-GGPVGVAVSPDGRRLYvanrgsntSNGGSNTVSVIDL 234
|
|
| WD40 |
smart00320 |
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ... |
560-599 |
2.19e-03 |
|
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.
Pssm-ID: 197651 [Multi-domain] Cd Length: 40 Bit Score: 36.52 E-value: 2.19e-03
10 20 30 40
....*....|....*....|....*....|....*....|
gi 755534474 560 TPRIKAELTSSAPACYALAVSPDAKVCFSCCSDGNIVVWD 599
Cdd:smart00320 1 SGELLKTLKGHTGPVTSVAFSPDGKYLASGSDDGTIKLWD 40
|
|
|