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Conserved domains on  [gi|767925482|ref|XP_011510627|]
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calcium-activated potassium channel subunit beta-2 isoform X1 [Homo sapiens]

Protein Classification

KcnmB2_inactiv and CaKB domain-containing protein( domain architecture ID 10558252)

KcnmB2_inactiv and CaKB domain-containing protein

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
CaKB pfam03185
Calcium-activated potassium channel, beta subunit;
38-229 2.38e-113

Calcium-activated potassium channel, beta subunit;


:

Pssm-ID: 460838  Cd Length: 195  Bit Score: 322.67  E-value: 2.38e-113
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767925482   38 TALKAGEDRAILLGLAMMVCSIMMYFLLGITLLRSYMQSVWTEESQCTLLNASIT-ETFNCSFSCGPDCWKLSQYPCLQV 116
Cdd:pfam03185   1 TASSAGEDRAILLGFAMMACSVLMYFVLGITVLKPYLQSVWTEEANCTVLNVDILdEWVDCSFSCGSDCRGVSQYPCLQV 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767925482  117 YVNLTSSGEKLLLYHTEETIKINQKCSYIPKCGKNFEESMSLVNVVMENFRKY--QHFSCYSDPEGNQKSVILTKLYSSN 194
Cdd:pfam03185  81 YVNLSSSGKVALLHHDEETLDLNPKCFYIPKCQRDYQELLESVENIKENFKKHngQPFPCYYDPSERPEDVILTRKYDPS 160
                         170       180       190
                  ....*....|....*....|....*....|....*
gi 767925482  195 VLFHSLFWPTCMMAGGVAIVAMVKLTQYLSLLCER 229
Cdd:pfam03185 161 VLLHCLLWPSLMLLGGVLIVGMVKLTQHLSVLCER 195
KcnmB2_inactiv pfam09303
KCNMB2, ball and chain domain; Members of this family are found in the cytoplasmic N-terminus ...
2-32 2.48e-11

KCNMB2, ball and chain domain; Members of this family are found in the cytoplasmic N-terminus of KCNMB2, the beta-2 subunit of large conductance calcium and voltage-activated potassium channels. They are responsible for the fast inactivation of these channels.


:

Pssm-ID: 401299  Cd Length: 30  Bit Score: 56.76  E-value: 2.48e-11
                          10        20        30
                  ....*....|....*....|....*....|.
gi 767925482    2 FIWTSGRTSSSyRHDEKRNIYQKIRDHDLLD 32
Cdd:pfam09303   1 FLWVGGRTTQS-FSTEQRSIYQKIREHDLLD 30
 
Name Accession Description Interval E-value
CaKB pfam03185
Calcium-activated potassium channel, beta subunit;
38-229 2.38e-113

Calcium-activated potassium channel, beta subunit;


Pssm-ID: 460838  Cd Length: 195  Bit Score: 322.67  E-value: 2.38e-113
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767925482   38 TALKAGEDRAILLGLAMMVCSIMMYFLLGITLLRSYMQSVWTEESQCTLLNASIT-ETFNCSFSCGPDCWKLSQYPCLQV 116
Cdd:pfam03185   1 TASSAGEDRAILLGFAMMACSVLMYFVLGITVLKPYLQSVWTEEANCTVLNVDILdEWVDCSFSCGSDCRGVSQYPCLQV 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767925482  117 YVNLTSSGEKLLLYHTEETIKINQKCSYIPKCGKNFEESMSLVNVVMENFRKY--QHFSCYSDPEGNQKSVILTKLYSSN 194
Cdd:pfam03185  81 YVNLSSSGKVALLHHDEETLDLNPKCFYIPKCQRDYQELLESVENIKENFKKHngQPFPCYYDPSERPEDVILTRKYDPS 160
                         170       180       190
                  ....*....|....*....|....*....|....*
gi 767925482  195 VLFHSLFWPTCMMAGGVAIVAMVKLTQYLSLLCER 229
Cdd:pfam03185 161 VLLHCLLWPSLMLLGGVLIVGMVKLTQHLSVLCER 195
KcnmB2_inactiv pfam09303
KCNMB2, ball and chain domain; Members of this family are found in the cytoplasmic N-terminus ...
2-32 2.48e-11

KCNMB2, ball and chain domain; Members of this family are found in the cytoplasmic N-terminus of KCNMB2, the beta-2 subunit of large conductance calcium and voltage-activated potassium channels. They are responsible for the fast inactivation of these channels.


Pssm-ID: 401299  Cd Length: 30  Bit Score: 56.76  E-value: 2.48e-11
                          10        20        30
                  ....*....|....*....|....*....|.
gi 767925482    2 FIWTSGRTSSSyRHDEKRNIYQKIRDHDLLD 32
Cdd:pfam09303   1 FLWVGGRTTQS-FSTEQRSIYQKIREHDLLD 30
 
Name Accession Description Interval E-value
CaKB pfam03185
Calcium-activated potassium channel, beta subunit;
38-229 2.38e-113

Calcium-activated potassium channel, beta subunit;


Pssm-ID: 460838  Cd Length: 195  Bit Score: 322.67  E-value: 2.38e-113
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767925482   38 TALKAGEDRAILLGLAMMVCSIMMYFLLGITLLRSYMQSVWTEESQCTLLNASIT-ETFNCSFSCGPDCWKLSQYPCLQV 116
Cdd:pfam03185   1 TASSAGEDRAILLGFAMMACSVLMYFVLGITVLKPYLQSVWTEEANCTVLNVDILdEWVDCSFSCGSDCRGVSQYPCLQV 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767925482  117 YVNLTSSGEKLLLYHTEETIKINQKCSYIPKCGKNFEESMSLVNVVMENFRKY--QHFSCYSDPEGNQKSVILTKLYSSN 194
Cdd:pfam03185  81 YVNLSSSGKVALLHHDEETLDLNPKCFYIPKCQRDYQELLESVENIKENFKKHngQPFPCYYDPSERPEDVILTRKYDPS 160
                         170       180       190
                  ....*....|....*....|....*....|....*
gi 767925482  195 VLFHSLFWPTCMMAGGVAIVAMVKLTQYLSLLCER 229
Cdd:pfam03185 161 VLLHCLLWPSLMLLGGVLIVGMVKLTQHLSVLCER 195
KcnmB2_inactiv pfam09303
KCNMB2, ball and chain domain; Members of this family are found in the cytoplasmic N-terminus ...
2-32 2.48e-11

KCNMB2, ball and chain domain; Members of this family are found in the cytoplasmic N-terminus of KCNMB2, the beta-2 subunit of large conductance calcium and voltage-activated potassium channels. They are responsible for the fast inactivation of these channels.


Pssm-ID: 401299  Cd Length: 30  Bit Score: 56.76  E-value: 2.48e-11
                          10        20        30
                  ....*....|....*....|....*....|.
gi 767925482    2 FIWTSGRTSSSyRHDEKRNIYQKIRDHDLLD 32
Cdd:pfam09303   1 FLWVGGRTTQS-FSTEQRSIYQKIREHDLLD 30
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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