NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|767927829|ref|XP_011511544|]
View 

DISP complex protein LRCH3 isoform X6 [Homo sapiens]

Protein Classification

leucine-rich repeat domain-containing protein( domain architecture ID 11469232)

leucine-rich repeat (LRR) domain-containing protein may participate in protein-protein interactions

Gene Ontology:  GO:0005515
PubMed:  11751054|7583641|14747988
SCOP:  4003523

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
80-286 3.79e-44

Leucine-rich repeat (LRR) protein [Transcription];


:

Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 162.41  E-value: 3.79e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767927829  80 DLTDTTRADLSRNRLSEIPIEACHFVSLENLNLYQNCIRYIPEAILNLQALTFLNISRNQLSTLPVHLCNLP-LKVLIAS 158
Cdd:COG4886  111 NLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQLTDLPEELGNLTnLKELDLS 190

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767927829 159 NNKLVSLPEEIGHLRHLMELDVSCNEIQTIPSQIGNLEALRDLNVRRNHLVHLPeELAELP-LIRLDFSCNKITTIPVCY 237
Cdd:COG4886  191 NNQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQLTDLP-ELGNLTnLEELDLSNNQLTDLPPLA 269

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 767927829 238 rNLRHLQTITLDNNPLQSPPAQICIKGKVHIFKYLNIQACKIAPDLPDY 286
Cdd:COG4886  270 -NLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILL 317
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
80-286 3.79e-44

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 162.41  E-value: 3.79e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767927829  80 DLTDTTRADLSRNRLSEIPIEACHFVSLENLNLYQNCIRYIPEAILNLQALTFLNISRNQLSTLPVHLCNLP-LKVLIAS 158
Cdd:COG4886  111 NLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQLTDLPEELGNLTnLKELDLS 190

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767927829 159 NNKLVSLPEEIGHLRHLMELDVSCNEIQTIPSQIGNLEALRDLNVRRNHLVHLPeELAELP-LIRLDFSCNKITTIPVCY 237
Cdd:COG4886  191 NNQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQLTDLP-ELGNLTnLEELDLSNNQLTDLPPLA 269

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 767927829 238 rNLRHLQTITLDNNPLQSPPAQICIKGKVHIFKYLNIQACKIAPDLPDY 286
Cdd:COG4886  270 -NLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILL 317
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
81-259 4.50e-14

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 75.50  E-value: 4.50e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767927829  81 LTDTTR-ADLSRNRLSEIPIeacHFVS-LENLNLYQNCIRYIPEAILnlQALTFLNISRNQLSTLPVHL----------- 147
Cdd:PRK15370 239 LPDTIQeMELSINRITELPE---RLPSaLQSLDLFHNKISCLPENLP--EELRYLSVYDNSIRTLPAHLpsgithlnvqs 313

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767927829 148 -------CNLP--LKVLIASNNKLVSLPEEIGhlRHLMELDVSCNEIQTIPSQIGnlEALRDLNVRRNHLVHLPEELAEl 218
Cdd:PRK15370 314 nsltalpETLPpgLKTLEAGENALTSLPASLP--PELQVLDVSKNQITVLPETLP--PTITTLDVSRNALTNLPENLPA- 388

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 767927829 219 PLIRLDFSCNKITTIPvcyRNLRHLQT-------ITLDNNPLQSPPAQ 259
Cdd:PRK15370 389 ALQIMQASRNNLVRLP---ESLPHFRGegpqptrIIVEYNPFSERTIQ 433
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 89-212 3.36e-12

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 65.96  E-value: 3.36e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767927829  89 LSRNRLSEI-PIEAChfVSLENLNLYQNCIRYIpEAILNLQALTFLNISRNQLStLPVHLCNLP---------LKVLIAS 158
Cdd:cd21340   53 LQNNQIEKIeNLENL--VNLKKLYLGGNRISVV-EGLENLTNLEELHIENQRLP-PGEKLTFDPrslaalsnsLRVLNIS 128

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 767927829 159 NNKLVSLpEEIGHLRHLMELDVSCNEIQTIPSQ---IGNLEALRDLNVRRNHLVHLP 212
Cdd:cd21340  129 GNNIDSL-EPLAPLRNLEQLDASNNQISDLEELldlLSSWPSLRELDLTGNPVCKKP 184
LRR_8 pfam13855
Leucine rich repeat;
152-208 5.41e-07

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 46.75  E-value: 5.41e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 767927829  152 LKVLIASNNKLVSLPEEI-GHLRHLMELDVSCNEIQTI-PSQIGNLEALRDLNVRRNHL 208
Cdd:pfam13855   3 LRSLDLSNNRLTSLDDGAfKGLSNLKVLDLSNNLLTTLsPGAFSGLPSLRYLDLSGNRL 61
 
Name Accession Description Interval E-value
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
80-286 3.79e-44

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 162.41  E-value: 3.79e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767927829  80 DLTDTTRADLSRNRLSEIPIEACHFVSLENLNLYQNCIRYIPEAILNLQALTFLNISRNQLSTLPVHLCNLP-LKVLIAS 158
Cdd:COG4886  111 NLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQLTDLPEELGNLTnLKELDLS 190

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767927829 159 NNKLVSLPEEIGHLRHLMELDVSCNEIQTIPSQIGNLEALRDLNVRRNHLVHLPeELAELP-LIRLDFSCNKITTIPVCY 237
Cdd:COG4886  191 NNQITDLPEPLGNLTNLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQLTDLP-ELGNLTnLEELDLSNNQLTDLPPLA 269

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 767927829 238 rNLRHLQTITLDNNPLQSPPAQICIKGKVHIFKYLNIQACKIAPDLPDY 286
Cdd:COG4886  270 -NLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILL 317
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
107-285 4.47e-27

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 113.88  E-value: 4.47e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767927829 107 LENLNLYQNCIRYIPEAILNLQALTFLNISRNQlstlpvHLCNLP-LKVLIASNNKLVSLPEEIGHLRHLMELDVSCNEI 185
Cdd:COG4886   75 LLLSLLLLSLLLLGLTDLGDLTNLTELDLSGNE------ELSNLTnLESLDLSGNQLTDLPEELANLTNLKELDLSNNQL 148

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767927829 186 QTIPSQIGNLEALRDLNVRRNHLVHLPEELAELP-LIRLDFSCNKITTIPVCYRNLRHLQTITLDNNPLQSPPAQIcikG 264
Cdd:COG4886  149 TDLPEPLGNLTNLKSLDLSNNQLTDLPEELGNLTnLKELDLSNNQITDLPEPLGNLTNLEELDLSGNQLTDLPEPL---A 225

                        170       180
                 ....*....|....*....|.
gi 767927829 265 KVHIFKYLNIQACKIApDLPD 285
Cdd:COG4886  226 NLTNLETLDLSNNQLT-DLPE 245
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
78-285 1.33e-19

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 91.53  E-value: 1.33e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767927829  78 NHDLTDTTRADLSRNRLSEIPIEACHFVSLENLNLYQNCIRYIPEAILNLQALTFLNISRNQLSTLPVHLCNLP-LKVLI 156
Cdd:COG4886   23 TLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTnLTELD 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767927829 157 ASNNklvslpEEIGHLRHLMELDVSCNEIQTIPSQIGNLEALRDLNVRRNHLVHLPEELAELP-LIRLDFSCNKITTIPV 235
Cdd:COG4886  103 LSGN------EELSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEPLGNLTnLKSLDLSNNQLTDLPE 176

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 767927829 236 CYRNLRHLQTITLDNNPLQSPPAQIcikGKVHIFKYLNIQACKIApDLPD 285
Cdd:COG4886  177 ELGNLTNLKELDLSNNQITDLPEPL---GNLTNLEELDLSGNQLT-DLPE 222
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
81-259 4.50e-14

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 75.50  E-value: 4.50e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767927829  81 LTDTTR-ADLSRNRLSEIPIeacHFVS-LENLNLYQNCIRYIPEAILnlQALTFLNISRNQLSTLPVHL----------- 147
Cdd:PRK15370 239 LPDTIQeMELSINRITELPE---RLPSaLQSLDLFHNKISCLPENLP--EELRYLSVYDNSIRTLPAHLpsgithlnvqs 313

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767927829 148 -------CNLP--LKVLIASNNKLVSLPEEIGhlRHLMELDVSCNEIQTIPSQIGnlEALRDLNVRRNHLVHLPEELAEl 218
Cdd:PRK15370 314 nsltalpETLPpgLKTLEAGENALTSLPASLP--PELQVLDVSKNQITVLPETLP--PTITTLDVSRNALTNLPENLPA- 388

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 767927829 219 PLIRLDFSCNKITTIPvcyRNLRHLQT-------ITLDNNPLQSPPAQ 259
Cdd:PRK15370 389 ALQIMQASRNNLVRLP---ESLPHFRGegpqptrIIVEYNPFSERTIQ 433
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 89-212 3.36e-12

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 65.96  E-value: 3.36e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767927829  89 LSRNRLSEI-PIEAChfVSLENLNLYQNCIRYIpEAILNLQALTFLNISRNQLStLPVHLCNLP---------LKVLIAS 158
Cdd:cd21340   53 LQNNQIEKIeNLENL--VNLKKLYLGGNRISVV-EGLENLTNLEELHIENQRLP-PGEKLTFDPrslaalsnsLRVLNIS 128

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 767927829 159 NNKLVSLpEEIGHLRHLMELDVSCNEIQTIPSQ---IGNLEALRDLNVRRNHLVHLP 212
Cdd:cd21340  129 GNNIDSL-EPLAPLRNLEQLDASNNQISDLEELldlLSSWPSLRELDLTGNPVCKKP 184
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 89-257 6.26e-12

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 65.19  E-value: 6.26e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767927829  89 LSRNRLSEIP-IEACHfvSLENLNLYQNCIRYIpEAILNLQALTFLNISRNQLSTLPvHLCNLP-LKVLIASNNKLVSLp 166
Cdd:cd21340    9 LNDKNITKIDnLSLCK--NLKVLYLYDNKITKI-ENLEFLTNLTHLYLQNNQIEKIE-NLENLVnLKKLYLGGNRISVV- 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767927829 167 EEIGHLRHLMELDVSCneiQTIP----------SQIGNLEALRDLNVRRNHLVHLpEELAELP-LIRLDFSCNKITTI-P 234
Cdd:cd21340   84 EGLENLTNLEELHIEN---QRLPpgekltfdprSLAALSNSLRVLNISGNNIDSL-EPLAPLRnLEQLDASNNQISDLeE 159

                        170       180
                 ....*....|....*....|....*
gi 767927829 235 VC--YRNLRHLQTITLDNNPLQSPP 257
Cdd:cd21340  160 LLdlLSSWPSLRELDLTGNPVCKKP 184
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 88-253 1.28e-11

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 67.57  E-value: 1.28e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767927829  88 DLSRNRLS-EIPIEACHFVSLENLNLYQNCIR-YIPEAILNLQALTFLNISRNQLS-TLPVHLCNL-PLK-VLIASNNKL 162
Cdd:PLN00113 146 DLSNNMLSgEIPNDIGSFSSLKVLDLGGNVLVgKIPNSLTNLTSLEFLTLASNQLVgQIPRELGQMkSLKwIYLGYNNLS 225

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767927829 163 VSLPEEIGHLRHLMELD-VSCNEIQTIPSQIGNLEALRDLNVRRNHLV-HLPEELAELP-LIRLDFSCNKIT-TIPVCYR 238
Cdd:PLN00113 226 GEIPYEIGGLTSLNHLDlVYNNLTGPIPSSLGNLKNLQYLFLYQNKLSgPIPPSIFSLQkLISLDLSDNSLSgEIPELVI 305

                        170
                 ....*....|....*
gi 767927829 239 NLRHLQTITLDNNPL 253
Cdd:PLN00113 306 QLQNLEILHLFSNNF 320
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
119-260 6.08e-10

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 62.02  E-value: 6.08e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767927829 119 YIPEAIlnlqalTFLNISRNQLSTLPVHLcNLPLKVLIASNNKLVSLPEEIGHLRHLMELD------------------- 179
Cdd:PRK15370 196 CIPEQI------TTLILDNNELKSLPENL-QGNIKTLYANSNQLTSIPATLPDTIQEMELSinritelperlpsalqsld 268

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767927829 180 VSCNEIQTIPSQIGnlEALRDLNVRRNHLVHLPEELAElPLIRLDFSCNKITTIPVCYRnlRHLQTITLDNNPLQSPPAQ 259
Cdd:PRK15370 269 LFHNKISCLPENLP--EELRYLSVYDNSIRTLPAHLPS-GITHLNVQSNSLTALPETLP--PGLKTLEAGENALTSLPAS 343


                 .
gi 767927829 260 I 260
Cdd:PRK15370 344 L 344
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
61-252 2.72e-09

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 59.56  E-value: 2.72e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767927829  61 VLSLSGRKLREFPRGAANhdLTDTTRADLSRNRLSEIPiEACHFVSLENLNLYQNCIRYIPEaILNLQALTFLNISRNQL 140
Cdd:COG4886  209 ELDLSGNQLTDLPEPLAN--LTNLETLDLSNNQLTDLP-ELGNLTNLEELDLSNNQLTDLPP-LANLTNLKTLDLSNNQL 284

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767927829 141 STLPV-HLCNLPLKVLIASNNKLVSLPEEIGHLRHLMELDVSCNEIQTIPSQIGNLEALRDLNVRRNHLVHLPEELAELP 219
Cdd:COG4886  285 TDLKLkELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLT 364

                        170       180       190
                 ....*....|....*....|....*....|...
gi 767927829 220 LIRLDFSCNKITTIPVCYRNLRHLQTITLDNNP 252
Cdd:COG4886  365 LLLTLGLLGLLEATLLTLALLLLTLLLLLLTTT 397
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 81-231 3.98e-09

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 59.48  E-value: 3.98e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767927829  81 LTDTTRADLSRNRLS-EIPIEACHFVSLENLNLYQNCIR-YIPEAILNLQALTFLNISRNQLS----------------- 141
Cdd:PLN00113 235 LTSLNHLDLVYNNLTgPIPSSLGNLKNLQYLFLYQNKLSgPIPPSIFSLQKLISLDLSDNSLSgeipelviqlqnleilh 314

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767927829 142 --------TLPVHLCNLP-LKVLIASNNKLV-SLPEEIGHLRHLMELDVSCNEIQ------------------------- 186
Cdd:PLN00113 315 lfsnnftgKIPVALTSLPrLQVLQLWSNKFSgEIPKNLGKHNNLTVLDLSTNNLTgeipeglcssgnlfklilfsnsleg 394

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 767927829 187 TIPSQIGNLEALRDLNVRRNHLV-HLPEELAELPLIR-LDFSCNKIT 231
Cdd:PLN00113 395 EIPKSLGACRSLRRVRLQDNSFSgELPSEFTKLPLVYfLDISNNNLQ 441
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 80-208 1.87e-08

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 57.55  E-value: 1.87e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767927829  80 DLTDTTRADLSRNRLS-EIPiEACHFVSLENLNLYQNCIR-YIPEAILNLQALTFLNISRNQLS-TLPVHLCNLP-LKVL 155
Cdd:PLN00113 450 DMPSLQMLSLARNKFFgGLP-DSFGSKRLENLDLSRNQFSgAVPRKLGSLSELMQLKLSENKLSgEIPDELSSCKkLVSL 528

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 767927829 156 IASNNKLV-SLPEEIGHLRHLMELDVSCNEIQ-TIPSQIGNLEALRDLNVRRNHL 208
Cdd:PLN00113 529 DLSHNQLSgQIPASFSEMPVLSQLDLSQNQLSgEIPKNLGNVESLVQVNISHNHL 583
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
107-285 2.88e-07

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 53.01  E-value: 2.88e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767927829 107 LENLNLYQNCIRYIPEAILNLQALTFLNISRNQLSTLPVHLCNLPLKVLIASNNKLVSLPEEIGHLRHLMELDV-----S 181
Cdd:COG4886    2 LLLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLllsllL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767927829 182 CNEIQTIPSQIGNLEALRDLNVRRNhlvhlpEELAELP-LIRLDFSCNKITTIPVCYRNLRHLQTITLDNNPLQSPPAQI 260
Cdd:COG4886   82 LSLLLLGLTDLGDLTNLTELDLSGN------EELSNLTnLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDLPEPL 155

                        170       180
                 ....*....|....*....|....*
gi 767927829 261 cikGKVHIFKYLNIQACKIApDLPD 285
Cdd:COG4886  156 ---GNLTNLKSLDLSNNQLT-DLPE 176
LRR_8 pfam13855
Leucine rich repeat;
152-208 5.41e-07

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 46.75  E-value: 5.41e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 767927829  152 LKVLIASNNKLVSLPEEI-GHLRHLMELDVSCNEIQTI-PSQIGNLEALRDLNVRRNHL 208
Cdd:pfam13855   3 LRSLDLSNNRLTSLDDGAfKGLSNLKVLDLSNNLLTTLsPGAFSGLPSLRYLDLSGNRL 61
PRK15387 PRK15387
type III secretion system effector E3 ubiquitin transferase SspH2;
81-247 1.63e-06

type III secretion system effector E3 ubiquitin transferase SspH2;


Pssm-ID: 185285 [Multi-domain]  Cd Length: 788  Bit Score: 51.32  E-value: 1.63e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767927829  81 LTDTTRADLSRNRLSEIPIEAChfvsleNLNLYQNCIRYIPEAILNLQALTflnISRNQLSTLPV-------------HL 147
Cdd:PRK15387 304 LQELSVSDNQLASLPALPSELC------KLWAYNNQLTSLPTLPSGLQELS---VSDNQLASLPTlpselyklwaynnRL 374

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767927829 148 CNLP-----LKVLIASNNKLVSLPEEIGHLRHLMeldVSCNEIQTIPSQIgnlEALRDLNVRRNHLVHLPEELAELplir 222
Cdd:PRK15387 375 TSLPalpsgLKELIVSGNRLTSLPVLPSELKELM---VSGNRLTSLPMLP---SGLLSLSVYRNQLTRLPESLIHL---- 444

                        170       180       190
                 ....*....|....*....|....*....|
gi 767927829 223 ldfscNKITTI-----PVCYRNLRHLQTIT 247
Cdd:PRK15387 445 -----SSETTVnlegnPLSERTLQALREIT 469
LRR_8 pfam13855
Leucine rich repeat;
173-253 6.93e-06

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 43.67  E-value: 6.93e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767927829  173 RHLMELDVSCNEIQTIPSqignlEALRDLNvrrnhlvhlpeelaelPLIRLDFSCNKITTI-PVCYRNLRHLQTITLDNN 251
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDD-----GAFKGLS----------------NLKVLDLSNNLLTTLsPGAFSGLPSLRYLDLSGN 59


                  ..
gi 767927829  252 PL 253
Cdd:pfam13855  60 RL 61
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 120-260 1.23e-03

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 41.76  E-value: 1.23e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767927829 120 IPEAILNLQALTFLNISRNQLS-TLPVHLCNL--PLKVLIASNNKLV-SLPEeiGHLRHLMELDVSCNEIQ-TIPSQIGN 194
Cdd:PLN00113  85 ISSAIFRLPYIQTINLSNNQLSgPIPDDIFTTssSLRYLNLSNNNFTgSIPR--GSIPNLETLDLSNNMLSgEIPNDIGS 162

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767927829 195 LEALRDLNVRRNHLV-HLPEELAELPLIR-LDFSCNKIT-TIPVCYRNLRHLQTITLDNNPLQSP-PAQI 260
Cdd:PLN00113 163 FSSLKVLDLGGNVLVgKIPNSLTNLTSLEfLTLASNQLVgQIPRELGQMKSLKWIYLGYNNLSGEiPYEI 232
LRR_8 pfam13855
Leucine rich repeat;
106-162 2.38e-03

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 36.35  E-value: 2.38e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 767927829  106 SLENLNLYQNCIRYI-PEAILNLQALTFLNISRNQLSTL-PVHLCNLP-LKVLIASNNKL 162
Cdd:pfam13855   2 NLRSLDLSNNRLTSLdDGAFKGLSNLKVLDLSNNLLTTLsPGAFSGLPsLRYLDLSGNRL 61
PLN03150 PLN03150
hypothetical protein; Provisional
 102-225 4.59e-03

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 39.80  E-value: 4.59e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767927829 102 CHFVS------LENLNLYQNCIR-YIPEAILNLQALTFLNISRNQLSTlpvhlcnlplkvliasnnklvSLPEEIGHLRH 174
Cdd:PLN03150 409 CQFDStkgkwfIDGLGLDNQGLRgFIPNDISKLRHLQSINLSGNSIRG---------------------NIPPSLGSITS 467

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 767927829 175 LMELDVSCNEIQ-TIPSQIGNLEALRDLNVRRNHLV-HLPEELAELPLIRLDF 225
Cdd:PLN03150 468 LEVLDLSYNSFNgSIPESLGQLTSLRILNLNGNSLSgRVPAALGGRLLHRASF 520
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH