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histone-lysine N-methyltransferase EZH2 isoform X26 [Homo sapiens]
List of domain hits
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Name | Accession | Description | Interval | E-value | |||
PRC2_HTH_1 | pfam18118 | Polycomb repressive complex 2 tri-helical domain; This domain can be found in the Polycomb ... |
166-257 | 3.11e-37 | |||
Polycomb repressive complex 2 tri-helical domain; This domain can be found in the Polycomb repressive complex 2 (PRC2) present in Homo sapiens. Polycomb complexes maintain repressive chromatin states by silencing gene expression. PRC2 does this by methylating lysine 27 of histone H3. This domain makes up part of the N-lobe which is involved in regulation. : Pssm-ID: 436286 Cd Length: 101 Bit Score: 132.51 E-value: 3.11e-37
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EZH2_WD-Binding | pfam11616 | WD repeat binding protein EZH2; This family of proteins represents Enhancer of zest homolog 2, ... |
47-76 | 4.23e-12 | |||
WD repeat binding protein EZH2; This family of proteins represents Enhancer of zest homolog 2, (EZH2) a 30 residue peptide which binds to a WD-repeat domain of EED by residues 39-68. EED is a component of PRC2 complex which is involved in gene expression. This interaction is required for the HMTase activity of PCR2. : Pssm-ID: 463308 Cd Length: 30 Bit Score: 60.16 E-value: 4.23e-12
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Name | Accession | Description | Interval | E-value | |||
PRC2_HTH_1 | pfam18118 | Polycomb repressive complex 2 tri-helical domain; This domain can be found in the Polycomb ... |
166-257 | 3.11e-37 | |||
Polycomb repressive complex 2 tri-helical domain; This domain can be found in the Polycomb repressive complex 2 (PRC2) present in Homo sapiens. Polycomb complexes maintain repressive chromatin states by silencing gene expression. PRC2 does this by methylating lysine 27 of histone H3. This domain makes up part of the N-lobe which is involved in regulation. Pssm-ID: 436286 Cd Length: 101 Bit Score: 132.51 E-value: 3.11e-37
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EZH2_WD-Binding | pfam11616 | WD repeat binding protein EZH2; This family of proteins represents Enhancer of zest homolog 2, ... |
47-76 | 4.23e-12 | |||
WD repeat binding protein EZH2; This family of proteins represents Enhancer of zest homolog 2, (EZH2) a 30 residue peptide which binds to a WD-repeat domain of EED by residues 39-68. EED is a component of PRC2 complex which is involved in gene expression. This interaction is required for the HMTase activity of PCR2. Pssm-ID: 463308 Cd Length: 30 Bit Score: 60.16 E-value: 4.23e-12
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Name | Accession | Description | Interval | E-value | |||
PRC2_HTH_1 | pfam18118 | Polycomb repressive complex 2 tri-helical domain; This domain can be found in the Polycomb ... |
166-257 | 3.11e-37 | |||
Polycomb repressive complex 2 tri-helical domain; This domain can be found in the Polycomb repressive complex 2 (PRC2) present in Homo sapiens. Polycomb complexes maintain repressive chromatin states by silencing gene expression. PRC2 does this by methylating lysine 27 of histone H3. This domain makes up part of the N-lobe which is involved in regulation. Pssm-ID: 436286 Cd Length: 101 Bit Score: 132.51 E-value: 3.11e-37
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EZH2_WD-Binding | pfam11616 | WD repeat binding protein EZH2; This family of proteins represents Enhancer of zest homolog 2, ... |
47-76 | 4.23e-12 | |||
WD repeat binding protein EZH2; This family of proteins represents Enhancer of zest homolog 2, (EZH2) a 30 residue peptide which binds to a WD-repeat domain of EED by residues 39-68. EED is a component of PRC2 complex which is involved in gene expression. This interaction is required for the HMTase activity of PCR2. Pssm-ID: 463308 Cd Length: 30 Bit Score: 60.16 E-value: 4.23e-12
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Blast search parameters | ||||
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