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Conserved domains on  [gi|767953077|ref|XP_011515372|]
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protein FAM135B isoform X6 [Homo sapiens]

Protein Classification

FAM135 family protein( domain architecture ID 10574879)

FAM135 family protein containing DUF3657 and DUF676 domains; belongs to the alpha/beta hydrolase superfamily

CATH:  3.40.50.1820
EC:  3.-.-.-
Gene Ontology:  GO:0016787
PubMed:  19508187|12369917
SCOP:  3000102

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF676 pfam05057
Putative serine esterase (DUF676); This family of proteins are probably serine esterase type ...
 1140-1216 1.02e-22

Putative serine esterase (DUF676); This family of proteins are probably serine esterase type enzymes with an alpha/beta hydrolase fold.


:

Pssm-ID: 309968  Cd Length: 212  Bit Score: 97.56  E-value: 1.02e-22
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767953077  1140 EDGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEKNQMDTFADFDTMTDRLLDEIIQHIQLYNlSISRI 1216
Cdd:pfam05057    2 SKKDHLVVLVHGLWGNSADMEYVAEQLEKKLPDELIVFLMSSNNVSKTFKGIDVMGERLANEVLEFVQDGS-DGKKI 77
DUF3657 pfam12394
Protein FAM135; This domain family is found in eukaryotes, and is approximately 60 amino acids ...
 111-172 3.54e-17

Protein FAM135; This domain family is found in eukaryotes, and is approximately 60 amino acids in length. The family is found in association with pfam05057.


:

Pssm-ID: 463558  Cd Length: 64  Bit Score: 76.87  E-value: 3.54e-17
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767953077   111 LKVDLHFTDSEQ---QLRDVAGAPMVSSRTLGLHfHPRNGLHHQVPVMFDYFHLSVISVTVHAAL 172
Cdd:pfam12394    1 LKVELMFADLDEnqsEPQLQSDFKCVSSRTLRIN-NALRGLHEYVPVIFDYFHFCLVEVTIHTSL 64
 
Name Accession Description Interval E-value
DUF676 pfam05057
Putative serine esterase (DUF676); This family of proteins are probably serine esterase type ...
 1140-1216 1.02e-22

Putative serine esterase (DUF676); This family of proteins are probably serine esterase type enzymes with an alpha/beta hydrolase fold.


Pssm-ID: 309968  Cd Length: 212  Bit Score: 97.56  E-value: 1.02e-22
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767953077  1140 EDGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEKNQMDTFADFDTMTDRLLDEIIQHIQLYNlSISRI 1216
Cdd:pfam05057    2 SKKDHLVVLVHGLWGNSADMEYVAEQLEKKLPDELIVFLMSSNNVSKTFKGIDVMGERLANEVLEFVQDGS-DGKKI 77
DUF3657 pfam12394
Protein FAM135; This domain family is found in eukaryotes, and is approximately 60 amino acids ...
 111-172 3.54e-17

Protein FAM135; This domain family is found in eukaryotes, and is approximately 60 amino acids in length. The family is found in association with pfam05057.


Pssm-ID: 463558  Cd Length: 64  Bit Score: 76.87  E-value: 3.54e-17
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767953077   111 LKVDLHFTDSEQ---QLRDVAGAPMVSSRTLGLHfHPRNGLHHQVPVMFDYFHLSVISVTVHAAL 172
Cdd:pfam12394    1 LKVELMFADLDEnqsEPQLQSDFKCVSSRTLRIN-NALRGLHEYVPVIFDYFHFCLVEVTIHTSL 64
 
Name Accession Description Interval E-value
DUF676 pfam05057
Putative serine esterase (DUF676); This family of proteins are probably serine esterase type ...
 1140-1216 1.02e-22

Putative serine esterase (DUF676); This family of proteins are probably serine esterase type enzymes with an alpha/beta hydrolase fold.


Pssm-ID: 309968  Cd Length: 212  Bit Score: 97.56  E-value: 1.02e-22
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767953077  1140 EDGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEKNQMDTFADFDTMTDRLLDEIIQHIQLYNlSISRI 1216
Cdd:pfam05057    2 SKKDHLVVLVHGLWGNSADMEYVAEQLEKKLPDELIVFLMSSNNVSKTFKGIDVMGERLANEVLEFVQDGS-DGKKI 77
DUF3657 pfam12394
Protein FAM135; This domain family is found in eukaryotes, and is approximately 60 amino acids ...
 111-172 3.54e-17

Protein FAM135; This domain family is found in eukaryotes, and is approximately 60 amino acids in length. The family is found in association with pfam05057.


Pssm-ID: 463558  Cd Length: 64  Bit Score: 76.87  E-value: 3.54e-17
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767953077   111 LKVDLHFTDSEQ---QLRDVAGAPMVSSRTLGLHfHPRNGLHHQVPVMFDYFHLSVISVTVHAAL 172
Cdd:pfam12394    1 LKVELMFADLDEnqsEPQLQSDFKCVSSRTLRIN-NALRGLHEYVPVIFDYFHFCLVEVTIHTSL 64
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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