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Conserved domains on  [gi|767954989|ref|XP_011516222|]
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equatorin isoform X1 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Afaf super family cl21182
Acrosome formation-associated factor; Afaf is a family of single pass type I membrane proteins. ...
 1-114 3.09e-64

Acrosome formation-associated factor; Afaf is a family of single pass type I membrane proteins. Afaf is a vesicle factor derived from the early endosome trafficking pathway that is involved in the biogenesis of the acrosome on the maturing spermatozoon head.


The actual alignment was detected with superfamily member pfam15339:

Pssm-ID: 464659  Cd Length: 193  Bit Score: 195.09  E-value: 3.09e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767954989    1 MLAKAINGTAVVMDDKDQLFHPIPESDVNATQGENQPDLEDLKIKIMLGISLMTLLLFVVLLAFCSATLYKLRHLSYKSC 80
Cdd:pfam15339  80 MLAKALNETAVSMDDKDQLFQPIPSSDLNATNEDKLSELEEIKLKLMLGISLMTLLLFLILLAFCSATLYKLKHLSYKSC 159

                          90       100       110
                  ....*....|....*....|....*....|....
gi 767954989   81 ESQYSVNPELATMSYFHPSEGVSDTSFSKSAESS 114
Cdd:pfam15339 160 ESQYSINPELATLSYFHPSEGVSDTSFSKSAESS 193
 
Name Accession Description Interval E-value
Afaf pfam15339
Acrosome formation-associated factor; Afaf is a family of single pass type I membrane proteins. ...
 1-114 3.09e-64

Acrosome formation-associated factor; Afaf is a family of single pass type I membrane proteins. Afaf is a vesicle factor derived from the early endosome trafficking pathway that is involved in the biogenesis of the acrosome on the maturing spermatozoon head.


Pssm-ID: 464659  Cd Length: 193  Bit Score: 195.09  E-value: 3.09e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767954989    1 MLAKAINGTAVVMDDKDQLFHPIPESDVNATQGENQPDLEDLKIKIMLGISLMTLLLFVVLLAFCSATLYKLRHLSYKSC 80
Cdd:pfam15339  80 MLAKALNETAVSMDDKDQLFQPIPSSDLNATNEDKLSELEEIKLKLMLGISLMTLLLFLILLAFCSATLYKLKHLSYKSC 159

                          90       100       110
                  ....*....|....*....|....*....|....
gi 767954989   81 ESQYSVNPELATMSYFHPSEGVSDTSFSKSAESS 114
Cdd:pfam15339 160 ESQYSINPELATLSYFHPSEGVSDTSFSKSAESS 193
 
Name Accession Description Interval E-value
Afaf pfam15339
Acrosome formation-associated factor; Afaf is a family of single pass type I membrane proteins. ...
 1-114 3.09e-64

Acrosome formation-associated factor; Afaf is a family of single pass type I membrane proteins. Afaf is a vesicle factor derived from the early endosome trafficking pathway that is involved in the biogenesis of the acrosome on the maturing spermatozoon head.


Pssm-ID: 464659  Cd Length: 193  Bit Score: 195.09  E-value: 3.09e-64
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767954989    1 MLAKAINGTAVVMDDKDQLFHPIPESDVNATQGENQPDLEDLKIKIMLGISLMTLLLFVVLLAFCSATLYKLRHLSYKSC 80
Cdd:pfam15339  80 MLAKALNETAVSMDDKDQLFQPIPSSDLNATNEDKLSELEEIKLKLMLGISLMTLLLFLILLAFCSATLYKLKHLSYKSC 159

                          90       100       110
                  ....*....|....*....|....*....|....
gi 767954989   81 ESQYSVNPELATMSYFHPSEGVSDTSFSKSAESS 114
Cdd:pfam15339 160 ESQYSINPELATLSYFHPSEGVSDTSFSKSAESS 193
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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