|
Name |
Accession |
Description |
Interval |
E-value |
| PIF1 |
pfam05970 |
PIF1-like helicase; This family includes homologs of the PIF1 helicase, which inhibits ... |
207-504 |
7.07e-123 |
|
PIF1-like helicase; This family includes homologs of the PIF1 helicase, which inhibits telomerase activity and is cell cycle regulated. This family includes a large number of largely uncharacterized plant proteins. This family includes a P-loop motif that is involved in nucleotide binding.
:
Pssm-ID: 428699 [Multi-domain] Cd Length: 361 Bit Score: 368.63 E-value: 7.07e-123
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767985447 207 LSEEQAAVLRAVL------KGQSIFFTGSAGTGKSYLLKRILGSLPPTG--TVATASTGVAACHI-GGTTLHAFAGIGSG 277
Cdd:pfam05970 1 LNDEQKKVFDAIIesvinnKGGVFFVYGYGGTGKTFLWKAIITSLRSEGkiVLAVASSGVAALLLpGGRTAHSRFGIPLD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767985447 278 QAPLAQCvALAQRPGVRQGWLNCQRLVIDEISMVEADLFDKLEAVARAVRQQ--NKPFGGIQLIICGDFLQLPPVT-KGS 354
Cdd:pfam05970 81 IDELSTC-KIKRGSKLAELLEKTSLIVWDEAPMTHRHCFEALDRTLRDILSEtdDKPFGGKTVVLGGDFRQILPVIpKGS 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767985447 355 QPPRFCF---QSKSWKRCVpvTLELTKVWRQAD-----------QTFISLLQAVRLGRCSDEVTRQ-------------- 406
Cdd:pfam05970 160 RPEIVNAsitNSYLWKHVK--VLELTKNMRLLAdsldqteakelQDFSDWLLAIGDGKINDENEREqlidipidillntg 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767985447 407 ---LQATASHKVGRdgIVA-----------TRLCTHQDDVALTNERRLQELPGKVHRFEAMDS--------------NPE 458
Cdd:pfam05970 238 gdpIEAIVSEVYPD--ILQnstdpnyleerAILCPTNEDVDEINNYRLSQLPGEEKEYLSSDSisksdndseidalyPTE 315
|
330 340 350 360
....*....|....*....|....*....|....*....|....*.
gi 767985447 459 LASTLDAQCPVSQLLQLKLGAQVMLVKNLSVSRGLVNGARGVVVGF 504
Cdd:pfam05970 316 FLNSLNANGLPNHVLKLKVGAPVMLLRNLDQSRGLCNGTRLIVTQL 361
|
|
| SF1_C_RecD |
cd18809 |
C-terminal helicase domain of RecD family helicases; RecD is a member of the RecBCD (EC 3.1.11. ... |
548-593 |
3.76e-16 |
|
C-terminal helicase domain of RecD family helicases; RecD is a member of the RecBCD (EC 3.1.11.5, Exonuclease V) complex. It is the alpha chain of the complex and functions as a 3'-5' helicase. The RecBCD enzyme is both a helicase that unwinds, or separates the strands of DNA, and a nuclease that makes single-stranded nicks in DNA. RecD family helicases are DEAD-like helicases belonging to superfamily (SF)1, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Similar to SF2 helicases, SF1 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
:
Pssm-ID: 350196 [Multi-domain] Cd Length: 80 Bit Score: 73.36 E-value: 3.76e-16
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 767985447 548 LAWAMSIHKSQGMTLDCVEISLGRV---FASGQAYVALSRARSLQGLRV 593
Cdd:cd18809 32 QAYAMTIHKSQGSEFDRVIVVLPTShpmLSRGLLYTALTRARKLLTLVG 80
|
|
| PRK13889 super family |
cl36309 |
conjugal transfer relaxase TraA; Provisional |
487-640 |
5.93e-04 |
|
conjugal transfer relaxase TraA; Provisional
The actual alignment was detected with superfamily member PRK13889:
Pssm-ID: 237546 [Multi-domain] Cd Length: 988 Bit Score: 43.14 E-value: 5.93e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767985447 487 LSVSRGLVNGARGVVVGFEAEGRGLPQVRFLCGVTEVIHADRWTVQATGGQLLS---RQQLPLQLAWAMSIHKSQGMTLD 563
Cdd:PRK13889 592 VTVERGERSFASGDRVMFLQNERGLGVKNGTLGTIEQVSAQSMSVRLDDGRSVAfdlKDYDRIDHGYAATIHKAQGMTVD 671
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767985447 564 CVEISLGRVFASGQAYVALSRARslqglrvldfDPMAvrcdprvLHF----YATLRR-GRSLSLESPDDdeAASDQENMD 638
Cdd:PRK13889 672 RTHVLATPGMDAHSSYVALSRHR----------DGVD-------LHYgrddFADRDRlVRTLSRDRAKD--MASDYERAD 732
|
..
gi 767985447 639 PI 640
Cdd:PRK13889 733 PA 734
|
|
| PHA03247 super family |
cl33720 |
large tegument protein UL36; Provisional |
27-209 |
3.06e-03 |
|
large tegument protein UL36; Provisional
The actual alignment was detected with superfamily member PHA03247:
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 41.08 E-value: 3.06e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767985447 27 SPGGQPRRRqALRTAELSLGRnerrelMLRLQAPGPAGRPRCFPLRAARLFTRFAEAGR-STLRLPAHDTPGAGAvqlll 105
Cdd:PHA03247 2678 SPPQRPRRR-AARPTVGSLTS------LADPPPPPPTPEPAPHALVSATPLPPGPAAARqASPALPAAPAPPAVP----- 2745
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767985447 106 sDCPPDRLRRFLRTLRLKLAAAPGPGPASARAQllGPRPRdfVTISPVQPEERRLRAATRVPDTTLVKRPVEPQAGAEPS 185
Cdd:PHA03247 2746 -AGPATPGGPARPARPPTTAGPPAPAPPAAPAA--GPPRR--LTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPP 2820
|
170 180
....*....|....*....|....
gi 767985447 186 TEAPRWPLPVKRLSLPSTKPQLSE 209
Cdd:PHA03247 2821 AASPAGPLPPPTSAQPTAPPPPPG 2844
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PIF1 |
pfam05970 |
PIF1-like helicase; This family includes homologs of the PIF1 helicase, which inhibits ... |
207-504 |
7.07e-123 |
|
PIF1-like helicase; This family includes homologs of the PIF1 helicase, which inhibits telomerase activity and is cell cycle regulated. This family includes a large number of largely uncharacterized plant proteins. This family includes a P-loop motif that is involved in nucleotide binding.
Pssm-ID: 428699 [Multi-domain] Cd Length: 361 Bit Score: 368.63 E-value: 7.07e-123
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767985447 207 LSEEQAAVLRAVL------KGQSIFFTGSAGTGKSYLLKRILGSLPPTG--TVATASTGVAACHI-GGTTLHAFAGIGSG 277
Cdd:pfam05970 1 LNDEQKKVFDAIIesvinnKGGVFFVYGYGGTGKTFLWKAIITSLRSEGkiVLAVASSGVAALLLpGGRTAHSRFGIPLD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767985447 278 QAPLAQCvALAQRPGVRQGWLNCQRLVIDEISMVEADLFDKLEAVARAVRQQ--NKPFGGIQLIICGDFLQLPPVT-KGS 354
Cdd:pfam05970 81 IDELSTC-KIKRGSKLAELLEKTSLIVWDEAPMTHRHCFEALDRTLRDILSEtdDKPFGGKTVVLGGDFRQILPVIpKGS 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767985447 355 QPPRFCF---QSKSWKRCVpvTLELTKVWRQAD-----------QTFISLLQAVRLGRCSDEVTRQ-------------- 406
Cdd:pfam05970 160 RPEIVNAsitNSYLWKHVK--VLELTKNMRLLAdsldqteakelQDFSDWLLAIGDGKINDENEREqlidipidillntg 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767985447 407 ---LQATASHKVGRdgIVA-----------TRLCTHQDDVALTNERRLQELPGKVHRFEAMDS--------------NPE 458
Cdd:pfam05970 238 gdpIEAIVSEVYPD--ILQnstdpnyleerAILCPTNEDVDEINNYRLSQLPGEEKEYLSSDSisksdndseidalyPTE 315
|
330 340 350 360
....*....|....*....|....*....|....*....|....*.
gi 767985447 459 LASTLDAQCPVSQLLQLKLGAQVMLVKNLSVSRGLVNGARGVVVGF 504
Cdd:pfam05970 316 FLNSLNANGLPNHVLKLKVGAPVMLLRNLDQSRGLCNGTRLIVTQL 361
|
|
| DEXSc_Pif1_like |
cd18037 |
DEAD-box helicase domain of Pif1; Pif1 and other members of this family are RecD-like ... |
210-381 |
1.57e-89 |
|
DEAD-box helicase domain of Pif1; Pif1 and other members of this family are RecD-like helicases involved in maintaining genome stability through unwinding double-stranded DNAs (dsDNAs), DNA/RNA hybrids, and G quadruplex (G4) structures. The members of Pif1 helicase subfamily studied so far all appear to contribute to telomere maintenance. Pif1 is a member of the DEAD-like helicases superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350795 [Multi-domain] Cd Length: 183 Bit Score: 275.67 E-value: 1.57e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767985447 210 EQAAVLRAVLKGQSIFFTGSAGTGKSYLLKRILGSLP--PTGTVATASTGVAACHIGGTTLHAFAGIGSGQAPLAQCVA- 286
Cdd:cd18037 1 EQRRVLDLVLDGKNVFFTGSAGTGKSYLLRRIIRALPsrPKRVAVTASTGIAACNIGGTTLHSFAGIGLGSEPAEDLLEr 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767985447 287 LAQRPGVRQGWLNCQRLVIDEISMVEADLFDKLEAVARAVRQQNKPFGGIQLIICGDFLQLPPVTKGSQPPRF------- 359
Cdd:cd18037 81 VKRSPYLVQRWRKCDVLIIDEISMLDADLFDKLDRVAREVRGSDKPFGGIQLILCGDFLQLPPVTKNSERQAFffrgdqq 160
|
170 180
....*....|....*....|...
gi 767985447 360 -CFQSKSWKRCVPVTLELTKVWR 381
Cdd:cd18037 161 fCFEAKSWERCIFLTVELTKVFR 183
|
|
| RecD |
COG0507 |
ATPase/5#-3# helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) ... |
201-606 |
2.21e-50 |
|
ATPase/5#-3# helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) [Replication, recombination and repair];
Pssm-ID: 440273 [Multi-domain] Cd Length: 514 Bit Score: 182.87 E-value: 2.21e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767985447 201 PSTKPQLSEEQAAVLRAVLKGQSIFF-TGSAGTGKSYLLKRILGSLPPTG--TVATASTGVAA------CHIGGTTLHAF 271
Cdd:COG0507 119 PRAGITLSDEQREAVALALTTRRVSVlTGGAGTGKTTTLRALLAALEALGlrVALAAPTGKAAkrlsesTGIEARTIHRL 198
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767985447 272 AGIGSGQAPLaqcvalaqRPGVRQGWLNCQRLVIDEISMVEADLFDKLeavARAVRQqnkpfGGIQLIICGDFLQLPPVT 351
Cdd:COG0507 199 LGLRPDSGRF--------RHNRDNPLTPADLLVVDEASMVDTRLMAAL---LEALPR-----AGARLILVGDPDQLPSVG 262
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767985447 352 KGSqpprfCFQSKSWKRCVPVTlELTKVWRQADQT-FISLLQAVRLGRCS------------------DEVTRQLQA--T 410
Cdd:COG0507 263 AGA-----VLRDLIESGTVPVV-ELTEVYRQADDSrIIELAHAIREGDAPealnaryadvvfveaedaEEAAEAIVElyA 336
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767985447 411 ASHKVGRDGIVatrLCTHQDDVALTNERRLQELPGkvhrfeamdsnpelASTLDAQCPVSQLLQLKLGAQVMLVKNlSVS 490
Cdd:COG0507 337 DRPAGGEDIQV---LAPTNAGVDALNQAIREALNP--------------AGELERELAEDGELELYVGDRVMFTRN-DYD 398
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767985447 491 RGLVNGARGVVVGFEAEGRGLpQVRFlcgvtevihaDRWTVQAtggqlLSRQQLP-LQLAWAMSIHKSQGMTLDCVEISL 569
Cdd:COG0507 399 LGVFNGDIGTVLSIDEDEGRL-TVRF----------DGREIVT-----YDPSELDqLELAYAITVHKSQGSTFDRVILVL 462
|
410 420 430 440
....*....|....*....|....*....|....*....|...
gi 767985447 570 G----RVFASGQAYVALSRARSLQGLrVLD--FDPMAVRCDPR 606
Cdd:COG0507 463 PsehsPLLSRELLYTALTRARELLTL-VGDrdALARAVRRDTA 504
|
|
| SF1_C_RecD |
cd18809 |
C-terminal helicase domain of RecD family helicases; RecD is a member of the RecBCD (EC 3.1.11. ... |
548-593 |
3.76e-16 |
|
C-terminal helicase domain of RecD family helicases; RecD is a member of the RecBCD (EC 3.1.11.5, Exonuclease V) complex. It is the alpha chain of the complex and functions as a 3'-5' helicase. The RecBCD enzyme is both a helicase that unwinds, or separates the strands of DNA, and a nuclease that makes single-stranded nicks in DNA. RecD family helicases are DEAD-like helicases belonging to superfamily (SF)1, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Similar to SF2 helicases, SF1 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350196 [Multi-domain] Cd Length: 80 Bit Score: 73.36 E-value: 3.76e-16
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 767985447 548 LAWAMSIHKSQGMTLDCVEISLGRV---FASGQAYVALSRARSLQGLRV 593
Cdd:cd18809 32 QAYAMTIHKSQGSEFDRVIVVLPTShpmLSRGLLYTALTRARKLLTLVG 80
|
|
| recD |
TIGR01447 |
exodeoxyribonuclease V, alpha subunit; This family describes the exodeoxyribonuclease V alpha ... |
187-621 |
1.77e-14 |
|
exodeoxyribonuclease V, alpha subunit; This family describes the exodeoxyribonuclease V alpha subunit, RecD. RecD is part of a RecBCD complex. A related family in the Gram-positive bacteria separates in a phylogenetic tree, has an additional N-terminal extension of about 200 residues, and is not supported as a member of a RecBCD complex by neighboring genes. The related family is consequently described by a different model. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273631 [Multi-domain] Cd Length: 582 Bit Score: 76.72 E-value: 1.77e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767985447 187 EAPRWPLPVKRLSLPSTKPQLSEEQAAVLRAVLKGQSIFFTGSAGTGKSYLLKRILGSL---------------PPTGTV 251
Cdd:TIGR01447 125 EARKRTAPSAILENLFPLLNEQNWRKTAVALALKSNFSLITGGPGTGKTTTVARLLLALvkqspkqgklrialaAPTGKA 204
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767985447 252 AT---------------ASTGVAACHIGGTTLHAFAGIGSGQAPLAQCvalaqrpgvRQGWLNCQRLVIDEISMVEADLF 316
Cdd:TIGR01447 205 AArlaeslrkavknlaaAEALIAALPSEAVTIHRLLGIKPDTKRFRHH---------ERNPLPLDVLVVDEASMVDLPLM 275
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767985447 317 DKLeavARAVRqqnkpfGGIQLIICGDFLQLPPVTKGSQPPRFCFQSKSWKRCVPVTLELTKVWRQ---ADQTF------ 387
Cdd:TIGR01447 276 AKL---LKALP------PNTKLILLGDKNQLPSVEAGAVLGDLCELASIGKSILYALCKKINSKTRnplSDNVCflktsh 346
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767985447 388 -------ISLL-QAVRLGRC----SDEVTRQLQATASHKVGRDGIVATRlcthqdDVALTNERRLQELpgkvHRFEAMDS 455
Cdd:TIGR01447 347 rfgkdsgIGQLaKAINSGDIeavlNNLRSGQLIEFEFLNSKEDAIERLK------NLYVKYRTFLQKL----AALSDAKE 416
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767985447 456 NPELASTLDAQCP--------------VSQLLQLK----------LGAQVMLVKNlSVSRGLVNGARGVVvgFEAEGRGL 511
Cdd:TIGR01447 417 ILETFDRLRLLTAlrdgpfgvlglnrrIEQELQEKyfdpdeegwyIGRPIMVTEN-DYTLGLFNGDIGVL--LRDPDGIL 493
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767985447 512 PQVRFLCGVTEVIHADRWTVQATggqllsrqqlplqlAWAMSIHKSQGMTLDCVEISL----GRVFASGQAYVALSRARs 587
Cdd:TIGR01447 494 TVWFHFADGSKAVLPSRLPNYET--------------AFAMTVHKSQGSEFDHVILILpngnSPVLTRELLYTGITRAK- 558
|
490 500 510
....*....|....*....|....*....|....
gi 767985447 588 lqglrvldfDPMAVRCDPRVLHfYATLRRGRSLS 621
Cdd:TIGR01447 559 ---------DQLSVWSDKETLN-AAIKRKNKRLS 582
|
|
| PHA03311 |
PHA03311 |
helicase-primase subunit BBLF4; Provisional |
551-599 |
3.85e-04 |
|
helicase-primase subunit BBLF4; Provisional
Pssm-ID: 223040 Cd Length: 782 Bit Score: 43.74 E-value: 3.85e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 767985447 551 AMSIHKSQGMTLDCVEISlgrvFASG------QAYVALSRARSLQGLRvLDFDPM 599
Cdd:PHA03311 706 AMTIAKSQGLSLDKVAIC----FGNHknlklsHVYVAMSRVTSSNFLV-MNLNPL 755
|
|
| Herpes_Helicase |
pfam02689 |
Helicase; This family consists of Helicases from the Herpes viruses. Helicases are responsible ... |
551-611 |
4.25e-04 |
|
Helicase; This family consists of Helicases from the Herpes viruses. Helicases are responsible for the unwinding of DNA and are essential for replication and completion of the viral life cycle.
Pssm-ID: 280797 Cd Length: 809 Bit Score: 43.55 E-value: 4.25e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767985447 551 AMSIHKSQGMTLDCVEISLG--RVFASGQAYVALSRARSLQGLrVLDFDPMAVR---------------CDPRVLHFY 611
Cdd:pfam02689 733 AMTIAKSQGLSLDKVAICFGnhPNLKLSHVYVAMSRATDPNHL-VMNVNPLRLRyekdnpiskhivkalKNPNTLLVY 809
|
|
| PRK13889 |
PRK13889 |
conjugal transfer relaxase TraA; Provisional |
487-640 |
5.93e-04 |
|
conjugal transfer relaxase TraA; Provisional
Pssm-ID: 237546 [Multi-domain] Cd Length: 988 Bit Score: 43.14 E-value: 5.93e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767985447 487 LSVSRGLVNGARGVVVGFEAEGRGLPQVRFLCGVTEVIHADRWTVQATGGQLLS---RQQLPLQLAWAMSIHKSQGMTLD 563
Cdd:PRK13889 592 VTVERGERSFASGDRVMFLQNERGLGVKNGTLGTIEQVSAQSMSVRLDDGRSVAfdlKDYDRIDHGYAATIHKAQGMTVD 671
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767985447 564 CVEISLGRVFASGQAYVALSRARslqglrvldfDPMAvrcdprvLHF----YATLRR-GRSLSLESPDDdeAASDQENMD 638
Cdd:PRK13889 672 RTHVLATPGMDAHSSYVALSRHR----------DGVD-------LHYgrddFADRDRlVRTLSRDRAKD--MASDYERAD 732
|
..
gi 767985447 639 PI 640
Cdd:PRK13889 733 PA 734
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
27-209 |
3.06e-03 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 41.08 E-value: 3.06e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767985447 27 SPGGQPRRRqALRTAELSLGRnerrelMLRLQAPGPAGRPRCFPLRAARLFTRFAEAGR-STLRLPAHDTPGAGAvqlll 105
Cdd:PHA03247 2678 SPPQRPRRR-AARPTVGSLTS------LADPPPPPPTPEPAPHALVSATPLPPGPAAARqASPALPAAPAPPAVP----- 2745
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767985447 106 sDCPPDRLRRFLRTLRLKLAAAPGPGPASARAQllGPRPRdfVTISPVQPEERRLRAATRVPDTTLVKRPVEPQAGAEPS 185
Cdd:PHA03247 2746 -AGPATPGGPARPARPPTTAGPPAPAPPAAPAA--GPPRR--LTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPP 2820
|
170 180
....*....|....*....|....
gi 767985447 186 TEAPRWPLPVKRLSLPSTKPQLSE 209
Cdd:PHA03247 2821 AASPAGPLPPPTSAQPTAPPPPPG 2844
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PIF1 |
pfam05970 |
PIF1-like helicase; This family includes homologs of the PIF1 helicase, which inhibits ... |
207-504 |
7.07e-123 |
|
PIF1-like helicase; This family includes homologs of the PIF1 helicase, which inhibits telomerase activity and is cell cycle regulated. This family includes a large number of largely uncharacterized plant proteins. This family includes a P-loop motif that is involved in nucleotide binding.
Pssm-ID: 428699 [Multi-domain] Cd Length: 361 Bit Score: 368.63 E-value: 7.07e-123
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767985447 207 LSEEQAAVLRAVL------KGQSIFFTGSAGTGKSYLLKRILGSLPPTG--TVATASTGVAACHI-GGTTLHAFAGIGSG 277
Cdd:pfam05970 1 LNDEQKKVFDAIIesvinnKGGVFFVYGYGGTGKTFLWKAIITSLRSEGkiVLAVASSGVAALLLpGGRTAHSRFGIPLD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767985447 278 QAPLAQCvALAQRPGVRQGWLNCQRLVIDEISMVEADLFDKLEAVARAVRQQ--NKPFGGIQLIICGDFLQLPPVT-KGS 354
Cdd:pfam05970 81 IDELSTC-KIKRGSKLAELLEKTSLIVWDEAPMTHRHCFEALDRTLRDILSEtdDKPFGGKTVVLGGDFRQILPVIpKGS 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767985447 355 QPPRFCF---QSKSWKRCVpvTLELTKVWRQAD-----------QTFISLLQAVRLGRCSDEVTRQ-------------- 406
Cdd:pfam05970 160 RPEIVNAsitNSYLWKHVK--VLELTKNMRLLAdsldqteakelQDFSDWLLAIGDGKINDENEREqlidipidillntg 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767985447 407 ---LQATASHKVGRdgIVA-----------TRLCTHQDDVALTNERRLQELPGKVHRFEAMDS--------------NPE 458
Cdd:pfam05970 238 gdpIEAIVSEVYPD--ILQnstdpnyleerAILCPTNEDVDEINNYRLSQLPGEEKEYLSSDSisksdndseidalyPTE 315
|
330 340 350 360
....*....|....*....|....*....|....*....|....*.
gi 767985447 459 LASTLDAQCPVSQLLQLKLGAQVMLVKNLSVSRGLVNGARGVVVGF 504
Cdd:pfam05970 316 FLNSLNANGLPNHVLKLKVGAPVMLLRNLDQSRGLCNGTRLIVTQL 361
|
|
| DEXSc_Pif1_like |
cd18037 |
DEAD-box helicase domain of Pif1; Pif1 and other members of this family are RecD-like ... |
210-381 |
1.57e-89 |
|
DEAD-box helicase domain of Pif1; Pif1 and other members of this family are RecD-like helicases involved in maintaining genome stability through unwinding double-stranded DNAs (dsDNAs), DNA/RNA hybrids, and G quadruplex (G4) structures. The members of Pif1 helicase subfamily studied so far all appear to contribute to telomere maintenance. Pif1 is a member of the DEAD-like helicases superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350795 [Multi-domain] Cd Length: 183 Bit Score: 275.67 E-value: 1.57e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767985447 210 EQAAVLRAVLKGQSIFFTGSAGTGKSYLLKRILGSLP--PTGTVATASTGVAACHIGGTTLHAFAGIGSGQAPLAQCVA- 286
Cdd:cd18037 1 EQRRVLDLVLDGKNVFFTGSAGTGKSYLLRRIIRALPsrPKRVAVTASTGIAACNIGGTTLHSFAGIGLGSEPAEDLLEr 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767985447 287 LAQRPGVRQGWLNCQRLVIDEISMVEADLFDKLEAVARAVRQQNKPFGGIQLIICGDFLQLPPVTKGSQPPRF------- 359
Cdd:cd18037 81 VKRSPYLVQRWRKCDVLIIDEISMLDADLFDKLDRVAREVRGSDKPFGGIQLILCGDFLQLPPVTKNSERQAFffrgdqq 160
|
170 180
....*....|....*....|...
gi 767985447 360 -CFQSKSWKRCVPVTLELTKVWR 381
Cdd:cd18037 161 fCFEAKSWERCIFLTVELTKVFR 183
|
|
| RecD |
COG0507 |
ATPase/5#-3# helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) ... |
201-606 |
2.21e-50 |
|
ATPase/5#-3# helicase helicase subunit RecD of the DNA repair enzyme RecBCD (exonuclease V) [Replication, recombination and repair];
Pssm-ID: 440273 [Multi-domain] Cd Length: 514 Bit Score: 182.87 E-value: 2.21e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767985447 201 PSTKPQLSEEQAAVLRAVLKGQSIFF-TGSAGTGKSYLLKRILGSLPPTG--TVATASTGVAA------CHIGGTTLHAF 271
Cdd:COG0507 119 PRAGITLSDEQREAVALALTTRRVSVlTGGAGTGKTTTLRALLAALEALGlrVALAAPTGKAAkrlsesTGIEARTIHRL 198
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767985447 272 AGIGSGQAPLaqcvalaqRPGVRQGWLNCQRLVIDEISMVEADLFDKLeavARAVRQqnkpfGGIQLIICGDFLQLPPVT 351
Cdd:COG0507 199 LGLRPDSGRF--------RHNRDNPLTPADLLVVDEASMVDTRLMAAL---LEALPR-----AGARLILVGDPDQLPSVG 262
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767985447 352 KGSqpprfCFQSKSWKRCVPVTlELTKVWRQADQT-FISLLQAVRLGRCS------------------DEVTRQLQA--T 410
Cdd:COG0507 263 AGA-----VLRDLIESGTVPVV-ELTEVYRQADDSrIIELAHAIREGDAPealnaryadvvfveaedaEEAAEAIVElyA 336
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767985447 411 ASHKVGRDGIVatrLCTHQDDVALTNERRLQELPGkvhrfeamdsnpelASTLDAQCPVSQLLQLKLGAQVMLVKNlSVS 490
Cdd:COG0507 337 DRPAGGEDIQV---LAPTNAGVDALNQAIREALNP--------------AGELERELAEDGELELYVGDRVMFTRN-DYD 398
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767985447 491 RGLVNGARGVVVGFEAEGRGLpQVRFlcgvtevihaDRWTVQAtggqlLSRQQLP-LQLAWAMSIHKSQGMTLDCVEISL 569
Cdd:COG0507 399 LGVFNGDIGTVLSIDEDEGRL-TVRF----------DGREIVT-----YDPSELDqLELAYAITVHKSQGSTFDRVILVL 462
|
410 420 430 440
....*....|....*....|....*....|....*....|...
gi 767985447 570 G----RVFASGQAYVALSRARSLQGLrVLD--FDPMAVRCDPR 606
Cdd:COG0507 463 PsehsPLLSRELLYTALTRARELLTL-VGDrdALARAVRRDTA 504
|
|
| DEXSc_RecD-like |
cd17933 |
DEXS-box helicase domain of RecD and similar proteins; RecD is a member of the RecBCD (EC 3.1. ... |
210-380 |
7.14e-30 |
|
DEXS-box helicase domain of RecD and similar proteins; RecD is a member of the RecBCD (EC 3.1.11.5, Exonuclease V) complex. It is the alpha chain of the complex and functions as a 3'-5' helicase. The RecBCD enzyme is both a helicase that unwinds, or separates the strands of DNA, and a nuclease that makes single-stranded nicks in DNA. RecD is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350691 [Multi-domain] Cd Length: 155 Bit Score: 115.34 E-value: 7.14e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767985447 210 EQAAVLRAVLKGQSIFFTGSAGTGKSYLLKRILGSL--PPTGTVATASTGVAACHIG------GTTLHAFAGIGSGQAPL 281
Cdd:cd17933 1 EQKAAVRLVLRNRVSVLTGGAGTGKTTTLKALLAALeaEGKRVVLAAPTGKAAKRLSestgieASTIHRLLGINPGGGGF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767985447 282 AQCvalaqrpgvRQGWLNCQRLVIDEISMVEADLFDKLEAVARAvrqqnkpfgGIQLIICGDFLQLPPVTKGSqPPRFCF 361
Cdd:cd17933 81 YYN---------EENPLDADLLIVDEASMVDTRLMAALLSAIPA---------GARLILVGDPDQLPSVGAGN-VLRDLI 141
|
170
....*....|....*....
gi 767985447 362 QSKSwkrcVPVTlELTKVW 380
Cdd:cd17933 142 ASKG----VPTV-ELTEVF 155
|
|
| SF1_C_RecD |
cd18809 |
C-terminal helicase domain of RecD family helicases; RecD is a member of the RecBCD (EC 3.1.11. ... |
548-593 |
3.76e-16 |
|
C-terminal helicase domain of RecD family helicases; RecD is a member of the RecBCD (EC 3.1.11.5, Exonuclease V) complex. It is the alpha chain of the complex and functions as a 3'-5' helicase. The RecBCD enzyme is both a helicase that unwinds, or separates the strands of DNA, and a nuclease that makes single-stranded nicks in DNA. RecD family helicases are DEAD-like helicases belonging to superfamily (SF)1, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Similar to SF2 helicases, SF1 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350196 [Multi-domain] Cd Length: 80 Bit Score: 73.36 E-value: 3.76e-16
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 767985447 548 LAWAMSIHKSQGMTLDCVEISLGRV---FASGQAYVALSRARSLQGLRV 593
Cdd:cd18809 32 QAYAMTIHKSQGSEFDRVIVVLPTShpmLSRGLLYTALTRARKLLTLVG 80
|
|
| recD |
TIGR01447 |
exodeoxyribonuclease V, alpha subunit; This family describes the exodeoxyribonuclease V alpha ... |
187-621 |
1.77e-14 |
|
exodeoxyribonuclease V, alpha subunit; This family describes the exodeoxyribonuclease V alpha subunit, RecD. RecD is part of a RecBCD complex. A related family in the Gram-positive bacteria separates in a phylogenetic tree, has an additional N-terminal extension of about 200 residues, and is not supported as a member of a RecBCD complex by neighboring genes. The related family is consequently described by a different model. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273631 [Multi-domain] Cd Length: 582 Bit Score: 76.72 E-value: 1.77e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767985447 187 EAPRWPLPVKRLSLPSTKPQLSEEQAAVLRAVLKGQSIFFTGSAGTGKSYLLKRILGSL---------------PPTGTV 251
Cdd:TIGR01447 125 EARKRTAPSAILENLFPLLNEQNWRKTAVALALKSNFSLITGGPGTGKTTTVARLLLALvkqspkqgklrialaAPTGKA 204
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767985447 252 AT---------------ASTGVAACHIGGTTLHAFAGIGSGQAPLAQCvalaqrpgvRQGWLNCQRLVIDEISMVEADLF 316
Cdd:TIGR01447 205 AArlaeslrkavknlaaAEALIAALPSEAVTIHRLLGIKPDTKRFRHH---------ERNPLPLDVLVVDEASMVDLPLM 275
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767985447 317 DKLeavARAVRqqnkpfGGIQLIICGDFLQLPPVTKGSQPPRFCFQSKSWKRCVPVTLELTKVWRQ---ADQTF------ 387
Cdd:TIGR01447 276 AKL---LKALP------PNTKLILLGDKNQLPSVEAGAVLGDLCELASIGKSILYALCKKINSKTRnplSDNVCflktsh 346
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767985447 388 -------ISLL-QAVRLGRC----SDEVTRQLQATASHKVGRDGIVATRlcthqdDVALTNERRLQELpgkvHRFEAMDS 455
Cdd:TIGR01447 347 rfgkdsgIGQLaKAINSGDIeavlNNLRSGQLIEFEFLNSKEDAIERLK------NLYVKYRTFLQKL----AALSDAKE 416
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767985447 456 NPELASTLDAQCP--------------VSQLLQLK----------LGAQVMLVKNlSVSRGLVNGARGVVvgFEAEGRGL 511
Cdd:TIGR01447 417 ILETFDRLRLLTAlrdgpfgvlglnrrIEQELQEKyfdpdeegwyIGRPIMVTEN-DYTLGLFNGDIGVL--LRDPDGIL 493
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767985447 512 PQVRFLCGVTEVIHADRWTVQATggqllsrqqlplqlAWAMSIHKSQGMTLDCVEISL----GRVFASGQAYVALSRARs 587
Cdd:TIGR01447 494 TVWFHFADGSKAVLPSRLPNYET--------------AFAMTVHKSQGSEFDHVILILpngnSPVLTRELLYTGITRAK- 558
|
490 500 510
....*....|....*....|....*....|....
gi 767985447 588 lqglrvldfDPMAVRCDPRVLHfYATLRRGRSLS 621
Cdd:TIGR01447 559 ---------DQLSVWSDKETLN-AAIKRKNKRLS 582
|
|
| AAA_30 |
pfam13604 |
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA ... |
206-398 |
1.40e-13 |
|
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily. Many of the proteins in this family are conjugative transfer proteins. There is a Walker A and Walker B.
Pssm-ID: 433343 [Multi-domain] Cd Length: 191 Bit Score: 69.52 E-value: 1.40e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767985447 206 QLSEEQAAVLRAVLKGQSIFF--TGSAGTGKSYLLK-----------RILGsLPPTGTVA---TASTGVAAchiggTTLH 269
Cdd:pfam13604 1 TLNAEQAAAVRALLTSGDRVAvlVGPAGTGKTTALKalreaweaagyRVIG-LAPTGRAAkvlGEELGIPA-----DTIA 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767985447 270 AFAGigsgqaplaqcvalaqRPGVRQGWLNCQRLVIDEISMVEADLFDKLEAVARAVrqqnkpfgGIQLIICGDFLQLPP 349
Cdd:pfam13604 75 KLLH----------------RLGGRAGLDPGTLLIVDEAGMVGTRQMARLLKLAEDA--------GARVILVGDPRQLPS 130
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 767985447 350 VTKGsQPPRFCFQSkswkrcVPVTLELTKVWRQADQTFISLLQAVRLGR 398
Cdd:pfam13604 131 VEAG-GAFRDLLAA------GIGTAELTEIVRQRDPWQRAASLALRDGD 172
|
|
| SF1_C |
cd18786 |
C-terminal helicase domain of superfamily 1 DEAD/H-box helicases; Superfamily (SF)1 family ... |
537-595 |
1.18e-10 |
|
C-terminal helicase domain of superfamily 1 DEAD/H-box helicases; Superfamily (SF)1 family members include UvrD/Rep, Pif1-like, and Upf-1-like proteins. Similar to SF2 helicases, they do not form toroidal, predominantly hexameric structures like SF3-6. SF1 helicases are a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. Their helicase core is surrounded by C- and N-terminal domains with specific functions such as nucleases, RNA or DNA binding domains, or domains engaged in protein-protein interactions. The core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350173 [Multi-domain] Cd Length: 89 Bit Score: 58.22 E-value: 1.18e-10
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 767985447 537 QLLSRQQLPLQLAWAMSIHKSQGMTLDCVEISLGRVFA--SGQAYVALSRARslQGLRVLD 595
Cdd:cd18786 31 QGLSLDEFDLQLVGAITIDSSQGLTFDVVTLYLPTANSltPRRLYVALTRAR--KRLVIYD 89
|
|
| TraA_Ti |
TIGR02768 |
Ti-type conjugative transfer relaxase TraA; This protein contains domains distinctive of a ... |
207-586 |
1.14e-08 |
|
Ti-type conjugative transfer relaxase TraA; This protein contains domains distinctive of a single strand exonuclease (N-terminus, MobA/MobL, pfam03389) as well as a helicase domain (central region, homologous to the corresponding region of the F-type relaxase TraI, TIGR02760). This protein likely fills the same role as TraI(F), nicking (at the oriT site) and unwinding the coiled plasmid prior to conjugative transfer.
Pssm-ID: 274289 [Multi-domain] Cd Length: 744 Bit Score: 58.28 E-value: 1.14e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767985447 207 LSEEQAAVLRAVLKGQSI-FFTGSAGTGKSYLLKRILGSLPPTG--TVATASTGVAAchiggTTLHAFAGI-----GSGQ 278
Cdd:TIGR02768 353 LSEEQYEAVRHVTGSGDIaVVVGRAGTGKSTMLKAAREAWEAAGyrVIGAALSGKAA-----EGLQAESGIesrtlASLE 427
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767985447 279 APLAQCVALAQRPGVrqgwlncqrLVIDEISMVEadlFDKLEAVARAVRQqnkpfGGIQLIICGDFLQLPPVTKGSqPPR 358
Cdd:TIGR02768 428 YAWANGRDLLSDKDV---------LVIDEAGMVG---SRQMARVLKEAEE-----AGAKVVLVGDPEQLQPIEAGA-AFR 489
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767985447 359 FCFQSKSWkrcvpvtLELTKVWRQADqtfiSLLQAVRLGRCSDEVTRQLQATASHkvGRDGIVATRLCTHQDDVALTNER 438
Cdd:TIGR02768 490 AIAERIGY-------AELETIRRQRE----AWARQASLELARGDVEKALAAYRDH--GHITIHDTREEAIEQVVADWKQD 556
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767985447 439 RLQELPGkvhrfeamDSNPELASTLDAQCPVSQLLQLKLGAQVMLVKNLSV--SRGLVNGARGVVVGFEAEGRGLPQVRF 516
Cdd:TIGR02768 557 LREANPA--------GSQIMLAHTRKDVRALNEAAREALIERGELGESILFqtARGERKFAAGDRIVFLENNRDLGVKNG 628
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767985447 517 LCGVTEVIHADRWTVQATGGQLLS---RQQLPLQLAWAMSIHKSQGMTLDCVeislgRVFASGQ-----AYVALSRAR 586
Cdd:TIGR02768 629 MLGTVEEIEDGRLVVQLDSGELVIipqAEYDALDHGYATTIHKSQGVTVDRA-----FVLASKSmdrhlAYVAMTRHR 701
|
|
| AAA_19 |
pfam13245 |
AAA domain; |
211-350 |
4.88e-07 |
|
AAA domain;
Pssm-ID: 433059 [Multi-domain] Cd Length: 136 Bit Score: 49.14 E-value: 4.88e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767985447 211 QAAVLRAVLKGQSIFFTGSAGTGKSYLLKRILGSL-------------PPTGTVA---TASTGVAAchiggTTLHAFAGI 274
Cdd:pfam13245 1 QREAVRTALPSKVVLLTGGPGTGKTTTIRHIVALLvalggvsfpillaAPTGRAAkrlSERTGLPA-----STIHRLLGF 75
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767985447 275 GsgqaPLAQCVALAQRPGVRQGWLncqrLVIDEISMVEADLFDKL-EAVARavrqqnkpfgGIQLIICGDFLQLPPV 350
Cdd:pfam13245 76 D----DLEAGGFLRDEEEPLDGDL----LIVDEFSMVDLPLAYRLlKALPD----------GAQLLLVGDPDQLPSV 134
|
|
| PHA03311 |
PHA03311 |
helicase-primase subunit BBLF4; Provisional |
551-599 |
3.85e-04 |
|
helicase-primase subunit BBLF4; Provisional
Pssm-ID: 223040 Cd Length: 782 Bit Score: 43.74 E-value: 3.85e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 767985447 551 AMSIHKSQGMTLDCVEISlgrvFASG------QAYVALSRARSLQGLRvLDFDPM 599
Cdd:PHA03311 706 AMTIAKSQGLSLDKVAIC----FGNHknlklsHVYVAMSRVTSSNFLV-MNLNPL 755
|
|
| Herpes_Helicase |
pfam02689 |
Helicase; This family consists of Helicases from the Herpes viruses. Helicases are responsible ... |
551-611 |
4.25e-04 |
|
Helicase; This family consists of Helicases from the Herpes viruses. Helicases are responsible for the unwinding of DNA and are essential for replication and completion of the viral life cycle.
Pssm-ID: 280797 Cd Length: 809 Bit Score: 43.55 E-value: 4.25e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767985447 551 AMSIHKSQGMTLDCVEISLG--RVFASGQAYVALSRARSLQGLrVLDFDPMAVR---------------CDPRVLHFY 611
Cdd:pfam02689 733 AMTIAKSQGLSLDKVAICFGnhPNLKLSHVYVAMSRATDPNHL-VMNVNPLRLRyekdnpiskhivkalKNPNTLLVY 809
|
|
| PRK13889 |
PRK13889 |
conjugal transfer relaxase TraA; Provisional |
487-640 |
5.93e-04 |
|
conjugal transfer relaxase TraA; Provisional
Pssm-ID: 237546 [Multi-domain] Cd Length: 988 Bit Score: 43.14 E-value: 5.93e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767985447 487 LSVSRGLVNGARGVVVGFEAEGRGLPQVRFLCGVTEVIHADRWTVQATGGQLLS---RQQLPLQLAWAMSIHKSQGMTLD 563
Cdd:PRK13889 592 VTVERGERSFASGDRVMFLQNERGLGVKNGTLGTIEQVSAQSMSVRLDDGRSVAfdlKDYDRIDHGYAATIHKAQGMTVD 671
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767985447 564 CVEISLGRVFASGQAYVALSRARslqglrvldfDPMAvrcdprvLHF----YATLRR-GRSLSLESPDDdeAASDQENMD 638
Cdd:PRK13889 672 RTHVLATPGMDAHSSYVALSRHR----------DGVD-------LHYgrddFADRDRlVRTLSRDRAKD--MASDYERAD 732
|
..
gi 767985447 639 PI 640
Cdd:PRK13889 733 PA 734
|
|
| AAA_22 |
pfam13401 |
AAA domain; |
222-342 |
1.00e-03 |
|
AAA domain;
Pssm-ID: 379165 [Multi-domain] Cd Length: 129 Bit Score: 39.63 E-value: 1.00e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767985447 222 QSIFFTGSAGTGKSYLLKRILGSLP--PTGTV---ATASTGVAAchIGGTTLHAFAGIGSGQAPLAQCVALAQRPGVRQG 296
Cdd:pfam13401 6 GILVLTGESGTGKTTLLRRLLEQLPevRDSVVfvdLPSGTSPKD--LLRALLRALGLPLSGRLSKEELLAALQQLLLALA 83
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 767985447 297 wlNCQRLVIDEISMVEADLFDKLeavaraVRQQNKPFGGIQLIICG 342
Cdd:pfam13401 84 --VAVVLIIDEAQHLSLEALEEL------RDLLNLSSKLLQLILVG 121
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
27-209 |
3.06e-03 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 41.08 E-value: 3.06e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767985447 27 SPGGQPRRRqALRTAELSLGRnerrelMLRLQAPGPAGRPRCFPLRAARLFTRFAEAGR-STLRLPAHDTPGAGAvqlll 105
Cdd:PHA03247 2678 SPPQRPRRR-AARPTVGSLTS------LADPPPPPPTPEPAPHALVSATPLPPGPAAARqASPALPAAPAPPAVP----- 2745
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767985447 106 sDCPPDRLRRFLRTLRLKLAAAPGPGPASARAQllGPRPRdfVTISPVQPEERRLRAATRVPDTTLVKRPVEPQAGAEPS 185
Cdd:PHA03247 2746 -AGPATPGGPARPARPPTTAGPPAPAPPAAPAA--GPPRR--LTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPP 2820
|
170 180
....*....|....*....|....
gi 767985447 186 TEAPRWPLPVKRLSLPSTKPQLSE 209
Cdd:PHA03247 2821 AASPAGPLPPPTSAQPTAPPPPPG 2844
|
|
| DEXXQc_Upf1-like |
cd17934 |
DEXXQ-box helicase domain of Upf1-like helicase; The Upf1-like helicase family includes UPF1, ... |
299-353 |
3.66e-03 |
|
DEXXQ-box helicase domain of Upf1-like helicase; The Upf1-like helicase family includes UPF1, HELZ, Mov10L1, Aquarius, IGHMBP2 (SMUBP2), coronavirus Nsp13, and similar proteins. They belong to the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 438708 [Multi-domain] Cd Length: 121 Bit Score: 37.60 E-value: 3.66e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 767985447 299 NCQRLVIDEISMV-EADLFdkleavarAVRQQNKpfggiQLIICGDFLQLPPVTKG 353
Cdd:cd17934 44 NVDVVIIDEASQItEPELL--------IALIRAK-----KVVLVGDPKQLPPVVQE 86
|
|
| UvrD_C_2 |
pfam13538 |
UvrD-like helicase C-terminal domain; This domain is found at the C-terminus of a wide variety ... |
548-586 |
8.45e-03 |
|
UvrD-like helicase C-terminal domain; This domain is found at the C-terminus of a wide variety of helicase enzymes. This domain has a AAA-like structural fold.
Pssm-ID: 463913 [Multi-domain] Cd Length: 52 Bit Score: 34.86 E-value: 8.45e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 767985447 548 LAWAMSIHKSQGMTLDCVEISLGRVFASGQA-------YVALSRAR 586
Cdd:pfam13538 1 LAYALTVHKAQGSEFPAVFLVDPDLTAHYHSmlrrrllYTAVTRAR 46
|
|
| |
