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host cell factor C1 regulator 1 isoform X2 [Homo sapiens]
List of domain hits
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Name | Accession | Description | Interval | E-value | ||
HPIP super family | cl21090 | HCF-1 beta-propeller-interacting protein family; HPIP is a small cellular polypeptide that ... |
1-71 | 2.24e-39 | ||
HCF-1 beta-propeller-interacting protein family; HPIP is a small cellular polypeptide that binds to the beta-propeller domain of HCF-1. HPIP regulates HCF-1 activity by modulating its subcellular localization. HCF-1 is a cellular protein required by VP16 to activate the herpes simplex virus- immediate-early genes. VP16 is a component of the viral tegument and, after release into the cell, binds to HCF-1 and translocates to the nucleus to form a complex with the POU domain protein Oct-1 and a VP16-responsive DNA sequence. HPIP-mediated export may provide the pool of cytoplasmic HCF-1 required for import of virion-derived VP16 into the nucleus. The actual alignment was detected with superfamily member pfam15226: Pssm-ID: 373659 Cd Length: 133 Bit Score: 126.25 E-value: 2.24e-39
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Name | Accession | Description | Interval | E-value | ||
HPIP | pfam15226 | HCF-1 beta-propeller-interacting protein family; HPIP is a small cellular polypeptide that ... |
1-71 | 2.24e-39 | ||
HCF-1 beta-propeller-interacting protein family; HPIP is a small cellular polypeptide that binds to the beta-propeller domain of HCF-1. HPIP regulates HCF-1 activity by modulating its subcellular localization. HCF-1 is a cellular protein required by VP16 to activate the herpes simplex virus- immediate-early genes. VP16 is a component of the viral tegument and, after release into the cell, binds to HCF-1 and translocates to the nucleus to form a complex with the POU domain protein Oct-1 and a VP16-responsive DNA sequence. HPIP-mediated export may provide the pool of cytoplasmic HCF-1 required for import of virion-derived VP16 into the nucleus. Pssm-ID: 373659 Cd Length: 133 Bit Score: 126.25 E-value: 2.24e-39
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Name | Accession | Description | Interval | E-value | ||
HPIP | pfam15226 | HCF-1 beta-propeller-interacting protein family; HPIP is a small cellular polypeptide that ... |
1-71 | 2.24e-39 | ||
HCF-1 beta-propeller-interacting protein family; HPIP is a small cellular polypeptide that binds to the beta-propeller domain of HCF-1. HPIP regulates HCF-1 activity by modulating its subcellular localization. HCF-1 is a cellular protein required by VP16 to activate the herpes simplex virus- immediate-early genes. VP16 is a component of the viral tegument and, after release into the cell, binds to HCF-1 and translocates to the nucleus to form a complex with the POU domain protein Oct-1 and a VP16-responsive DNA sequence. HPIP-mediated export may provide the pool of cytoplasmic HCF-1 required for import of virion-derived VP16 into the nucleus. Pssm-ID: 373659 Cd Length: 133 Bit Score: 126.25 E-value: 2.24e-39
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Blast search parameters | ||||
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