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Conserved domains on  [gi|768004725|ref|XP_011526729|]
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peroxisomal membrane protein 11C isoform X3 [Homo sapiens]

Protein Classification

PEX11 family protein( domain architecture ID 140502)

peroxin-11 (PEX11) family protein is a membrane elongation factor that coordinates peroxisome proliferation and maintenance

Gene Ontology:  GO:0005778|GO:0016559
PubMed:  20826455

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PEX11 super family cl20302
Peroxisomal biogenesis factor 11 (PEX11); This family consists of several peroxisomal ...
 4-143 5.59e-41

Peroxisomal biogenesis factor 11 (PEX11); This family consists of several peroxisomal biogenesis factor 11 (PEX11) proteins from several eukaryotic species. The PEX11 peroxisomal membrane proteins promote peroxisome division in multiple eukaryotes.


The actual alignment was detected with superfamily member pfam05648:

Pssm-ID: 398979  Cd Length: 223  Bit Score: 138.17  E-value: 5.59e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768004725    4 LSGLASALESYRGRDRLIRVLGYCCQLVGGVLVEQCPaRSEVGTRLLVVSTQLSHCRTILRLFDDLAMFVYTKQYgLGAQ 83
Cdd:pfam05648   1 LDHLVRFLASTVGRDKLLRTLQYASRLLAYYLERKGS-SPELVDKLKNLESQFSLSRKLLRLGKFLNHLQAAAKY-YDNK 78

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 768004725   84 EEDAFVRCVSVLGNLADQLYYPCEHVAWAADARVLHVDSS-RWWTLSTTLWALSLLLGVAR 143
Cdd:pfam05648  79 LPDPVLRLLAVLRNLGYALYLFLDHVLWLARTGLLKVKNAkRWSRISSRFWLFGLVLSLVR 139
 
Name Accession Description Interval E-value
PEX11 pfam05648
Peroxisomal biogenesis factor 11 (PEX11); This family consists of several peroxisomal ...
 4-143 5.59e-41

Peroxisomal biogenesis factor 11 (PEX11); This family consists of several peroxisomal biogenesis factor 11 (PEX11) proteins from several eukaryotic species. The PEX11 peroxisomal membrane proteins promote peroxisome division in multiple eukaryotes.


Pssm-ID: 398979  Cd Length: 223  Bit Score: 138.17  E-value: 5.59e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768004725    4 LSGLASALESYRGRDRLIRVLGYCCQLVGGVLVEQCPaRSEVGTRLLVVSTQLSHCRTILRLFDDLAMFVYTKQYgLGAQ 83
Cdd:pfam05648   1 LDHLVRFLASTVGRDKLLRTLQYASRLLAYYLERKGS-SPELVDKLKNLESQFSLSRKLLRLGKFLNHLQAAAKY-YDNK 78

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 768004725   84 EEDAFVRCVSVLGNLADQLYYPCEHVAWAADARVLHVDSS-RWWTLSTTLWALSLLLGVAR 143
Cdd:pfam05648  79 LPDPVLRLLAVLRNLGYALYLFLDHVLWLARTGLLKVKNAkRWSRISSRFWLFGLVLSLVR 139
 
Name Accession Description Interval E-value
PEX11 pfam05648
Peroxisomal biogenesis factor 11 (PEX11); This family consists of several peroxisomal ...
 4-143 5.59e-41

Peroxisomal biogenesis factor 11 (PEX11); This family consists of several peroxisomal biogenesis factor 11 (PEX11) proteins from several eukaryotic species. The PEX11 peroxisomal membrane proteins promote peroxisome division in multiple eukaryotes.


Pssm-ID: 398979  Cd Length: 223  Bit Score: 138.17  E-value: 5.59e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 768004725    4 LSGLASALESYRGRDRLIRVLGYCCQLVGGVLVEQCPaRSEVGTRLLVVSTQLSHCRTILRLFDDLAMFVYTKQYgLGAQ 83
Cdd:pfam05648   1 LDHLVRFLASTVGRDKLLRTLQYASRLLAYYLERKGS-SPELVDKLKNLESQFSLSRKLLRLGKFLNHLQAAAKY-YDNK 78

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 768004725   84 EEDAFVRCVSVLGNLADQLYYPCEHVAWAADARVLHVDSS-RWWTLSTTLWALSLLLGVAR 143
Cdd:pfam05648  79 LPDPVLRLLAVLRNLGYALYLFLDHVLWLARTGLLKVKNAkRWSRISSRFWLFGLVLSLVR 139
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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