pyridoxal kinase isoform X6 [Homo sapiens]
Protein Classification
List of domain hits
| Name | Accession | Description | Interval | E-value | ||
| ribokinase_pfkB_like super family | cl00192 | ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including ... |
105-141 | 4.62e-06 | ||
ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase, 2-dehydro-3-deoxygluconokinase, 1-phosphofructokinase, the minor 6-phosphofructokinase (PfkB), inosine-guanosine kinase, and adenosine kinase. Even though there is a high degree of structural conservation within this superfamily, their multimerization level varies widely, monomeric (e.g. adenosine kinase), dimeric (e.g. ribokinase), and trimeric (e.g THZ kinase). The actual alignment was detected with superfamily member TIGR00687: Pssm-ID: 469648 [Multi-domain] Cd Length: 287 Bit Score: 45.21 E-value: 4.62e-06
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| ribokinase_pfkB_like super family | cl00192 | ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including ... |
125-172 | 9.08e-05 | ||
ribokinase/pfkB superfamily: Kinases that accept a wide variety of substrates, including carbohydrates and aromatic small molecules, all are phosphorylated at a hydroxyl group. The superfamily includes ribokinase, fructokinase, ketohexokinase, 2-dehydro-3-deoxygluconokinase, 1-phosphofructokinase, the minor 6-phosphofructokinase (PfkB), inosine-guanosine kinase, and adenosine kinase. Even though there is a high degree of structural conservation within this superfamily, their multimerization level varies widely, monomeric (e.g. adenosine kinase), dimeric (e.g. ribokinase), and trimeric (e.g THZ kinase). The actual alignment was detected with superfamily member cd01173: Pssm-ID: 469648 [Multi-domain] Cd Length: 254 Bit Score: 41.42 E-value: 9.08e-05
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| Name | Accession | Description | Interval | E-value | ||
| pyridox_kin | TIGR00687 | pyridoxal kinase; E. coli has an enzyme PdxK that acts in vitro as a pyridoxine/pyridoxal ... |
105-141 | 4.62e-06 | ||
pyridoxal kinase; E. coli has an enzyme PdxK that acts in vitro as a pyridoxine/pyridoxal/pyridoxamine kinase, but mutants lacking PdxK activity retain a specific pyridoxal kinase, PdxY. PdxY acts in the salvage pathway of pyridoxal 5'-phosphate biosynthesis. Mammalian forms of pyridoxal kinase are more similar to PdxY than to PdxK. The PdxK isozyme is omitted from the seed alignment but scores above the trusted cutoff.ThiD and related proteins form an outgroup. [Biosynthesis of cofactors, prosthetic groups, and carriers, Pyridoxine] Pssm-ID: 273221 [Multi-domain] Cd Length: 287 Bit Score: 45.21 E-value: 4.62e-06
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| PLN02978 | PLN02978 | pyridoxal kinase |
112-141 | 7.06e-06 | ||
pyridoxal kinase Pssm-ID: 215529 [Multi-domain] Cd Length: 308 Bit Score: 44.73 E-value: 7.06e-06
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| pyridoxal_pyridoxamine_kinase | cd01173 | Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5 ... |
125-172 | 9.08e-05 | ||
Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate (PLP), by catalyzing the phosphorylation of the precursor vitamin B6 in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and require its precursors in the form of vitamin B6 (pyridoxal, pyridoxine, and pyridoxamine) from their diet. Pyridoxal kinase encoding genes are also found in many other species including yeast and bacteria. Pssm-ID: 238578 [Multi-domain] Cd Length: 254 Bit Score: 41.42 E-value: 9.08e-05
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| Name | Accession | Description | Interval | E-value | ||
| pyridox_kin | TIGR00687 | pyridoxal kinase; E. coli has an enzyme PdxK that acts in vitro as a pyridoxine/pyridoxal ... |
105-141 | 4.62e-06 | ||
pyridoxal kinase; E. coli has an enzyme PdxK that acts in vitro as a pyridoxine/pyridoxal/pyridoxamine kinase, but mutants lacking PdxK activity retain a specific pyridoxal kinase, PdxY. PdxY acts in the salvage pathway of pyridoxal 5'-phosphate biosynthesis. Mammalian forms of pyridoxal kinase are more similar to PdxY than to PdxK. The PdxK isozyme is omitted from the seed alignment but scores above the trusted cutoff.ThiD and related proteins form an outgroup. [Biosynthesis of cofactors, prosthetic groups, and carriers, Pyridoxine] Pssm-ID: 273221 [Multi-domain] Cd Length: 287 Bit Score: 45.21 E-value: 4.62e-06
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| PLN02978 | PLN02978 | pyridoxal kinase |
112-141 | 7.06e-06 | ||
pyridoxal kinase Pssm-ID: 215529 [Multi-domain] Cd Length: 308 Bit Score: 44.73 E-value: 7.06e-06
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| PTZ00344 | PTZ00344 | pyridoxal kinase; Provisional |
121-142 | 5.35e-05 | ||
pyridoxal kinase; Provisional Pssm-ID: 240372 [Multi-domain] Cd Length: 296 Bit Score: 42.38 E-value: 5.35e-05
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| pyridoxal_pyridoxamine_kinase | cd01173 | Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5 ... |
125-172 | 9.08e-05 | ||
Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate (PLP), by catalyzing the phosphorylation of the precursor vitamin B6 in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and require its precursors in the form of vitamin B6 (pyridoxal, pyridoxine, and pyridoxamine) from their diet. Pyridoxal kinase encoding genes are also found in many other species including yeast and bacteria. Pssm-ID: 238578 [Multi-domain] Cd Length: 254 Bit Score: 41.42 E-value: 9.08e-05
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