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Conserved domains on  [gi|767932772|ref|XP_011530600|]
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ADP/ATP translocase 4 isoform X1 [Homo sapiens]

Protein Classification

ADP/ATP carrier family protein( domain architecture ID 1000309)

ADP/ATP carrier family protein may provide transport for nucleotides, amino acids, carboxylic acids, fatty acids, cofactors, or inorganic ions across a membrane; similar to mitochondrial adenine nucleotide carriers

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PTZ00169 super family cl36523
ADP/ATP transporter on adenylate translocase; Provisional
 19-218 8.52e-77

ADP/ATP transporter on adenylate translocase; Provisional


The actual alignment was detected with superfamily member PTZ00169:

Pssm-ID: 240302 [Multi-domain]  Cd Length: 300  Bit Score: 233.12  E-value: 8.52e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932772  19 SFGKDLLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPE--ARYKGMVDCLVRIPREQGFFSFWRGNLANVIRYFPT 96
Cdd:PTZ00169   6 NFATDFLMGGISAAISKTAVAPIERVKMLIQTQDSIPEIKSGkvPRYSGIVNCFRRVSKEQGVLSLWRGNTANVIRYFPT 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932772  97 QALNFAFKDKYKQLF-----------------MSG------------------------VNKEKQ--------------- 120
Cdd:PTZ00169  86 QAFNFAFKDYFKNMFpkynqktdfwkffgvniLSGglagassllivypldfartrlasdIGKGGDreftglfdclmkisk 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932772 121 ---------------------------------GLLPKPKK-TPFLVSFFIAQVVTTCSGILSYPFDTVRRRMMMQSGEA 166
Cdd:PTZ00169 166 qtgflslyqgfgvsvqgiivyrgayfglydsakALLFGNDKnTNILYKWAVAQTVTILAGLISYPFDTVRRRMMMMSGRK 245

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 767932772 167 KR---QYKGTLDCFVKIYQHEGISSFFRGAFSNVLRGTGGALVLVLYDKIKEFFH 218
Cdd:PTZ00169 246 AKseiQYTGTLDCWKKILKNEGLGGFFKGAWANVLRGAGGALVLVFYDELQKLLK 300
 
Name Accession Description Interval E-value
PTZ00169 PTZ00169
ADP/ATP transporter on adenylate translocase; Provisional
 19-218 8.52e-77

ADP/ATP transporter on adenylate translocase; Provisional


Pssm-ID: 240302 [Multi-domain]  Cd Length: 300  Bit Score: 233.12  E-value: 8.52e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932772  19 SFGKDLLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPE--ARYKGMVDCLVRIPREQGFFSFWRGNLANVIRYFPT 96
Cdd:PTZ00169   6 NFATDFLMGGISAAISKTAVAPIERVKMLIQTQDSIPEIKSGkvPRYSGIVNCFRRVSKEQGVLSLWRGNTANVIRYFPT 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932772  97 QALNFAFKDKYKQLF-----------------MSG------------------------VNKEKQ--------------- 120
Cdd:PTZ00169  86 QAFNFAFKDYFKNMFpkynqktdfwkffgvniLSGglagassllivypldfartrlasdIGKGGDreftglfdclmkisk 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932772 121 ---------------------------------GLLPKPKK-TPFLVSFFIAQVVTTCSGILSYPFDTVRRRMMMQSGEA 166
Cdd:PTZ00169 166 qtgflslyqgfgvsvqgiivyrgayfglydsakALLFGNDKnTNILYKWAVAQTVTILAGLISYPFDTVRRRMMMMSGRK 245

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 767932772 167 KR---QYKGTLDCFVKIYQHEGISSFFRGAFSNVLRGTGGALVLVLYDKIKEFFH 218
Cdd:PTZ00169 246 AKseiQYTGTLDCWKKILKNEGLGGFFKGAWANVLRGAGGALVLVFYDELQKLLK 300
Mito_carr pfam00153
Mitochondrial carrier protein;
16-112 1.02e-30

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 108.90  E-value: 1.02e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932772   16 DASSFGKDLLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQispeARYKGMVDCLVRIPREQGFFSFWRGNLANVIRYFP 95
Cdd:pfam00153   1 SELSFLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQGGSGK----SKGRGILDCFKKIYKEEGIRGLYKGLLPNLLRVAP 76

                          90
                  ....*....|....*..
gi 767932772   96 TQALNFAFKDKYKQLFM 112
Cdd:pfam00153  77 AAAIYFGTYETLKRLLL 93
 
Name Accession Description Interval E-value
PTZ00169 PTZ00169
ADP/ATP transporter on adenylate translocase; Provisional
 19-218 8.52e-77

ADP/ATP transporter on adenylate translocase; Provisional


Pssm-ID: 240302 [Multi-domain]  Cd Length: 300  Bit Score: 233.12  E-value: 8.52e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932772  19 SFGKDLLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQISPE--ARYKGMVDCLVRIPREQGFFSFWRGNLANVIRYFPT 96
Cdd:PTZ00169   6 NFATDFLMGGISAAISKTAVAPIERVKMLIQTQDSIPEIKSGkvPRYSGIVNCFRRVSKEQGVLSLWRGNTANVIRYFPT 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932772  97 QALNFAFKDKYKQLF-----------------MSG------------------------VNKEKQ--------------- 120
Cdd:PTZ00169  86 QAFNFAFKDYFKNMFpkynqktdfwkffgvniLSGglagassllivypldfartrlasdIGKGGDreftglfdclmkisk 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932772 121 ---------------------------------GLLPKPKK-TPFLVSFFIAQVVTTCSGILSYPFDTVRRRMMMQSGEA 166
Cdd:PTZ00169 166 qtgflslyqgfgvsvqgiivyrgayfglydsakALLFGNDKnTNILYKWAVAQTVTILAGLISYPFDTVRRRMMMMSGRK 245

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 767932772 167 KR---QYKGTLDCFVKIYQHEGISSFFRGAFSNVLRGTGGALVLVLYDKIKEFFH 218
Cdd:PTZ00169 246 AKseiQYTGTLDCWKKILKNEGLGGFFKGAWANVLRGAGGALVLVFYDELQKLLK 300
Mito_carr pfam00153
Mitochondrial carrier protein;
16-112 1.02e-30

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 108.90  E-value: 1.02e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932772   16 DASSFGKDLLAGGVAAAVSKTAVAPIERVKLLLQVQASSKQispeARYKGMVDCLVRIPREQGFFSFWRGNLANVIRYFP 95
Cdd:pfam00153   1 SELSFLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQGGSGK----SKGRGILDCFKKIYKEEGIRGLYKGLLPNLLRVAP 76

                          90
                  ....*....|....*..
gi 767932772   96 TQALNFAFKDKYKQLFM 112
Cdd:pfam00153  77 AAAIYFGTYETLKRLLL 93
Mito_carr pfam00153
Mitochondrial carrier protein;
127-218 2.95e-22

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 86.94  E-value: 2.95e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767932772  127 KKTPFLVSFFIAQVVTTCSGILSYPFDTVRRRMMMQSGEAKRQYKGTLDCFVKIYQHEGISSFFRGAFSNVLR-GTGGAL 205
Cdd:pfam00153   1 SELSFLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQGGSGKSKGRGILDCFKKIYKEEGIRGLYKGLLPNLLRvAPAAAI 80

                          90
                  ....*....|...
gi 767932772  206 VLVLYDKIKEFFH 218
Cdd:pfam00153  81 YFGTYETLKRLLL 93
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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