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Conserved domains on  [gi|767977027|ref|XP_011533107|]
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fibrosin-1-like protein isoform X5 [Homo sapiens]

Protein Classification

fibrosin/Auts2 domain-containing protein( domain architecture ID 10633998)

fibrosin/Auts2 domain-containing protein similar to human fibrosin-1-like protein, also called autism susceptibility candidate 2 (AUTS2)-like protein

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Auts2 pfam15336
Autism susceptibility gene 2 protein; Auts2, or FBRSL2, Fibrosin-1-like protein 2, is a family ...
581-827 5.96e-73

Autism susceptibility gene 2 protein; Auts2, or FBRSL2, Fibrosin-1-like protein 2, is a family of eukaryotic proteins associated both with a susceptibility to autism and with influencing the number of corpora lutea produced by breeding sows.


:

Pssm-ID: 464656  Cd Length: 217  Bit Score: 240.90  E-value: 5.96e-73
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977027   581 KPGRWCAVHVQIAWQIYRHQQKIKEMQLDPHKLEVGAKLDLFGRPPAPGVFAGFHYPQDLARP--LFPSTGharewevkv 658
Cdd:pfam15336    1 KPGKWCAMHVRIAWQIYHHQQKVKQMQLDPHKLDVGLKLELLSRPPGPGVFGGFPYPHDLARPatLFSATG--------- 71
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977027   659 hrgnwgapceqscrwealvlspgfcqtwlpppgAAHPASNPFGPSAHPGSFLPTGPLTDPFSRPSTFGGLGSLSSHAFGG 738
Cdd:pfam15336   72 ---------------------------------AAHPSATPFGPSPPHGSFLSPASHLDPFSRPSTFGGLGALSSGAFGG 118
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977027   739 LGSHALAPGgSIFAPKEGSSVHGLPSPHEAWNRLHRAPPSFPAPPPWPKSVDAERVSALTNHDREPDN-----------G 807
Cdd:pfam15336  119 LGSPSLTAN-SVFGHKEGPPLQGFSSPHDPWNRLHRTPPSFPTPPPWPKPGDAERSSSLESHERERDRererekrdssvI 197
                          250       260
                   ....*....|....*....|
gi 767977027   808 KEEQERDLLEKTRLLSRASP 827
Cdd:pfam15336  198 KDEKDRDSLDKNRHSSRSSP 217
 
Name Accession Description Interval E-value
Auts2 pfam15336
Autism susceptibility gene 2 protein; Auts2, or FBRSL2, Fibrosin-1-like protein 2, is a family ...
581-827 5.96e-73

Autism susceptibility gene 2 protein; Auts2, or FBRSL2, Fibrosin-1-like protein 2, is a family of eukaryotic proteins associated both with a susceptibility to autism and with influencing the number of corpora lutea produced by breeding sows.


Pssm-ID: 464656  Cd Length: 217  Bit Score: 240.90  E-value: 5.96e-73
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977027   581 KPGRWCAVHVQIAWQIYRHQQKIKEMQLDPHKLEVGAKLDLFGRPPAPGVFAGFHYPQDLARP--LFPSTGharewevkv 658
Cdd:pfam15336    1 KPGKWCAMHVRIAWQIYHHQQKVKQMQLDPHKLDVGLKLELLSRPPGPGVFGGFPYPHDLARPatLFSATG--------- 71
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977027   659 hrgnwgapceqscrwealvlspgfcqtwlpppgAAHPASNPFGPSAHPGSFLPTGPLTDPFSRPSTFGGLGSLSSHAFGG 738
Cdd:pfam15336   72 ---------------------------------AAHPSATPFGPSPPHGSFLSPASHLDPFSRPSTFGGLGALSSGAFGG 118
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977027   739 LGSHALAPGgSIFAPKEGSSVHGLPSPHEAWNRLHRAPPSFPAPPPWPKSVDAERVSALTNHDREPDN-----------G 807
Cdd:pfam15336  119 LGSPSLTAN-SVFGHKEGPPLQGFSSPHDPWNRLHRTPPSFPTPPPWPKPGDAERSSSLESHERERDRererekrdssvI 197
                          250       260
                   ....*....|....*....|
gi 767977027   808 KEEQERDLLEKTRLLSRASP 827
Cdd:pfam15336  198 KDEKDRDSLDKNRHSSRSSP 217
 
Name Accession Description Interval E-value
Auts2 pfam15336
Autism susceptibility gene 2 protein; Auts2, or FBRSL2, Fibrosin-1-like protein 2, is a family ...
581-827 5.96e-73

Autism susceptibility gene 2 protein; Auts2, or FBRSL2, Fibrosin-1-like protein 2, is a family of eukaryotic proteins associated both with a susceptibility to autism and with influencing the number of corpora lutea produced by breeding sows.


Pssm-ID: 464656  Cd Length: 217  Bit Score: 240.90  E-value: 5.96e-73
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977027   581 KPGRWCAVHVQIAWQIYRHQQKIKEMQLDPHKLEVGAKLDLFGRPPAPGVFAGFHYPQDLARP--LFPSTGharewevkv 658
Cdd:pfam15336    1 KPGKWCAMHVRIAWQIYHHQQKVKQMQLDPHKLDVGLKLELLSRPPGPGVFGGFPYPHDLARPatLFSATG--------- 71
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977027   659 hrgnwgapceqscrwealvlspgfcqtwlpppgAAHPASNPFGPSAHPGSFLPTGPLTDPFSRPSTFGGLGSLSSHAFGG 738
Cdd:pfam15336   72 ---------------------------------AAHPSATPFGPSPPHGSFLSPASHLDPFSRPSTFGGLGALSSGAFGG 118
                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767977027   739 LGSHALAPGgSIFAPKEGSSVHGLPSPHEAWNRLHRAPPSFPAPPPWPKSVDAERVSALTNHDREPDN-----------G 807
Cdd:pfam15336  119 LGSPSLTAN-SVFGHKEGPPLQGFSSPHDPWNRLHRTPPSFPTPPPWPKPGDAERSSSLESHERERDRererekrdssvI 197
                          250       260
                   ....*....|....*....|
gi 767977027   808 KEEQERDLLEKTRLLSRASP 827
Cdd:pfam15336  198 KDEKDRDSLDKNRHSSRSSP 217
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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