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Conserved domains on  [gi|767979724|ref|XP_011534735|]
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tetratricopeptide repeat protein 8 isoform X1 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
TTC8_N cd21341
N-terminal domain of tetratricopeptide repeat domain 8; Tetratricopeptide repeat domain 8 ...
 30-169 3.48e-90

N-terminal domain of tetratricopeptide repeat domain 8; Tetratricopeptide repeat domain 8 (TTC80), also known a BBS8, has been directly linked to Bardet-Biedl syndrome, an autosomal recessive ciliopathy characterized by retinal degeneration, renal failure, obesity, diabetes, male infertility, polydactyly and cognitive impairment. Mutations in BBS8 cause early vision loss. In addition to C-terminal tetratricopeptide repeats, TTC8 also contains an N-terminal domain of unknown function.


:

Pssm-ID: 411061 [Multi-domain]  Cd Length: 139  Bit Score: 271.48  E-value: 3.48e-90
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767979724  30 MLEKSPYDQAAWILKARALTEMVYIDEIDVDQEGIAEMMLDENAIAQVPRPGTSLKLPGTNQtGGPSQAVRPITQAGRPI 109
Cdd:cd21341    1 LLEKNPYDQAAWFLKMRALTEQVYIDDTEVDEEGIAELLMDENVIATVPRPGTSLRRPTTSA-GGPSQAMRPTTSSGRPI 79

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 767979724 110 TGFLRPSTQSGRPGTMEQAIRTPRTAYTARPITSSSGRFVRLGTASMLTSPDGPFINLSR 169
Cdd:cd21341   80 TGFVRPGTQSGRPGTSRQALRTPRRAGTARPVTSASGRFVRLGTASMLSGPDGPFINVSR 139
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 248-482 1.02e-21

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 94.80  E-value: 1.02e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767979724 248 GKCYYRLGMYREAEKQFKSALKQ-QEMVDTFLYLAKVYVSLDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNMSS 326
Cdd:COG2956   15 GLNYLLNGQPDKAIDLLEEALELdPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDR 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767979724 327 AAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEIALRFYRRLLQMGIYNGQLFNNLGLCCFYAQQYDMTLTSFERALSLA 406
Cdd:COG2956   95 AEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLD 174

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767979724 407 ENeeeAADVWYNLGHVAVGIGDTNLAHQCFRLALVNNNNHAEAYNNLAVLEMRKGHVEQIGDLQRSYVAAQKSEAA 482
Cdd:COG2956  175 PD---CARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDL 247
 
Name Accession Description Interval E-value
TTC8_N cd21341
N-terminal domain of tetratricopeptide repeat domain 8; Tetratricopeptide repeat domain 8 ...
 30-169 3.48e-90

N-terminal domain of tetratricopeptide repeat domain 8; Tetratricopeptide repeat domain 8 (TTC80), also known a BBS8, has been directly linked to Bardet-Biedl syndrome, an autosomal recessive ciliopathy characterized by retinal degeneration, renal failure, obesity, diabetes, male infertility, polydactyly and cognitive impairment. Mutations in BBS8 cause early vision loss. In addition to C-terminal tetratricopeptide repeats, TTC8 also contains an N-terminal domain of unknown function.


Pssm-ID: 411061 [Multi-domain]  Cd Length: 139  Bit Score: 271.48  E-value: 3.48e-90
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767979724  30 MLEKSPYDQAAWILKARALTEMVYIDEIDVDQEGIAEMMLDENAIAQVPRPGTSLKLPGTNQtGGPSQAVRPITQAGRPI 109
Cdd:cd21341    1 LLEKNPYDQAAWFLKMRALTEQVYIDDTEVDEEGIAELLMDENVIATVPRPGTSLRRPTTSA-GGPSQAMRPTTSSGRPI 79

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 767979724 110 TGFLRPSTQSGRPGTMEQAIRTPRTAYTARPITSSSGRFVRLGTASMLTSPDGPFINLSR 169
Cdd:cd21341   80 TGFVRPGTQSGRPGTSRQALRTPRRAGTARPVTSASGRFVRLGTASMLSGPDGPFINVSR 139
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 248-482 1.02e-21

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 94.80  E-value: 1.02e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767979724 248 GKCYYRLGMYREAEKQFKSALKQ-QEMVDTFLYLAKVYVSLDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNMSS 326
Cdd:COG2956   15 GLNYLLNGQPDKAIDLLEEALELdPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDR 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767979724 327 AAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEIALRFYRRLLQMGIYNGQLFNNLGLCCFYAQQYDMTLTSFERALSLA 406
Cdd:COG2956   95 AEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLD 174

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767979724 407 ENeeeAADVWYNLGHVAVGIGDTNLAHQCFRLALVNNNNHAEAYNNLAVLEMRKGHVEQIGDLQRSYVAAQKSEAA 482
Cdd:COG2956  175 PD---CARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDL 247
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 218-476 2.15e-07

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 53.55  E-value: 2.15e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767979724  218 KNHIEKNALDLAAlstehsqykdwwwKVQIGKCYYRLGMYREAEKQFKSALKQQ-EMVDTFLYLAKVYVSLDQPVTAL-- 294
Cdd:TIGR02917  46 KNALQKDPNDAEA-------------RFLLGKIYLALGDYAAAEKELRKALSLGyPKNQVLPLLARAYLLQGKFQQVLde 112

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767979724  295 ---------------------------------NLFKQGLDKFPGEVTLLCGIARIYEEMNNMSSAAEYYKEVLKQDNTH 341
Cdd:TIGR02917 113 lpgktllddegaaellalrglaylglgqlelaqKSYEQALAIDPRSLYAKLGLAQLALAENRFDEARALIDEVLTADPGN 192

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767979724  342 VEAIACIGSNHFYSDQPEIALRFYRRLLQMGIYNGQLFNNLGLCCFYAQQYDMTLTSFERALSLAENEEEAAdvwYNLGH 421
Cdd:TIGR02917 193 VDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEEAEKHADALLKKAPNSPLAH---YLKAL 269

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 767979724  422 VAVGIGDTNLAHQCFRLALVNNNNHAEAYNNLAVLEMRKGHVEQIGDLQRSYVAA 476
Cdd:TIGR02917 270 VDFQKKNYEDARETLQDALKSAPEYLPALLLAGASEYQLGNLEQAYQYLNQILKY 324
TPR_12 pfam13424
Tetratricopeptide repeat;
380-440 1.95e-04

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 40.06  E-value: 1.95e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767979724  380 NNLGLCCFYAQQYDMTLTSFERALSLAENE-----EEAADVWYNLGHVAVGIGDTNLAHQCFRLAL 440
Cdd:pfam13424   7 NNLAAVLRRLGRYDEALELLEKALEIARRLlgpdhPLTATTLLNLGRLYLELGRYEEALELLERAL 72
LPA1 PLN03098
LOW PSII ACCUMULATION1; Provisional
 381-444 2.72e-03

LOW PSII ACCUMULATION1; Provisional


Pssm-ID: 215573 [Multi-domain]  Cd Length: 453  Bit Score: 40.26  E-value: 2.72e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767979724 381 NLGLCCFYAQQYDMTLTSFERALSLAENEEEAADVWYNLGHVAVGIGDTNLAHQCFRLALVNNN 444
Cdd:PLN03098  80 NLGLSLFSKGRVKDALAQFETALELNPNPDEAQAAYYNKACCHAYREEGKKAADCLRTALRDYN 143
 
Name Accession Description Interval E-value
TTC8_N cd21341
N-terminal domain of tetratricopeptide repeat domain 8; Tetratricopeptide repeat domain 8 ...
 30-169 3.48e-90

N-terminal domain of tetratricopeptide repeat domain 8; Tetratricopeptide repeat domain 8 (TTC80), also known a BBS8, has been directly linked to Bardet-Biedl syndrome, an autosomal recessive ciliopathy characterized by retinal degeneration, renal failure, obesity, diabetes, male infertility, polydactyly and cognitive impairment. Mutations in BBS8 cause early vision loss. In addition to C-terminal tetratricopeptide repeats, TTC8 also contains an N-terminal domain of unknown function.


Pssm-ID: 411061 [Multi-domain]  Cd Length: 139  Bit Score: 271.48  E-value: 3.48e-90
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767979724  30 MLEKSPYDQAAWILKARALTEMVYIDEIDVDQEGIAEMMLDENAIAQVPRPGTSLKLPGTNQtGGPSQAVRPITQAGRPI 109
Cdd:cd21341    1 LLEKNPYDQAAWFLKMRALTEQVYIDDTEVDEEGIAELLMDENVIATVPRPGTSLRRPTTSA-GGPSQAMRPTTSSGRPI 79

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 767979724 110 TGFLRPSTQSGRPGTMEQAIRTPRTAYTARPITSSSGRFVRLGTASMLTSPDGPFINLSR 169
Cdd:cd21341   80 TGFVRPGTQSGRPGTSRQALRTPRRAGTARPVTSASGRFVRLGTASMLSGPDGPFINVSR 139
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 248-482 1.02e-21

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 94.80  E-value: 1.02e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767979724 248 GKCYYRLGMYREAEKQFKSALKQ-QEMVDTFLYLAKVYVSLDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNMSS 326
Cdd:COG2956   15 GLNYLLNGQPDKAIDLLEEALELdPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDR 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767979724 327 AAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEIALRFYRRLLQMGIYNGQLFNNLGLCCFYAQQYDMTLTSFERALSLA 406
Cdd:COG2956   95 AEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALKLD 174

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767979724 407 ENeeeAADVWYNLGHVAVGIGDTNLAHQCFRLALVNNNNHAEAYNNLAVLEMRKGHVEQIGDLQRSYVAAQKSEAA 482
Cdd:COG2956  175 PD---CARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDL 247
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
305-482 2.24e-20

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 90.45  E-value: 2.24e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767979724 305 PGEVTLLCGIARIYEEMNNMSSAAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEIALRFYRRLLQMGIYNGQLFNNLGL 384
Cdd:COG0457    5 PDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGL 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767979724 385 CCFYAQQYDMTLTSFERALSLAENEeeaADVWYNLGHVAVGIGDTNLAHQCFRLALVNNNNHAEAYNNLAVLEMRKGHVE 464
Cdd:COG0457   85 ALQALGRYEEALEDYDKALELDPDD---AEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYE 161

                        170
                 ....*....|....*....
gi 767979724 465 Q-IGDLQRSYVAAQKSEAA 482
Cdd:COG0457  162 EaLELLEKLEAAALAALLA 180
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
272-498 1.55e-18

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 85.06  E-value: 1.55e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767979724 272 EMVDTFLYLAKVYVSLDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNMSSAAEYYKEVLKQDNTHVEAIACIGSN 351
Cdd:COG0457    6 DDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLA 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767979724 352 HFYSDQPEIALRFYRRLLQMGIYNGQLFNNLGLCCFYAQQYDMTLTSFERALSLAENEEEAadvWYNLGHVAVGIGDTNL 431
Cdd:COG0457   86 LQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADA---LYNLGIALEKLGRYEE 162

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767979724 432 AHQCFRLALVNNNNHAEAYNNLAVLEMRKGHVEQIGDLQRSYVAAQKSEAAFPDHVDTQHLIKQLRQ 498
Cdd:COG0457  163 ALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALAL 229
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
247-477 1.58e-17

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 81.98  E-value: 1.58e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767979724 247 IGKCYYRLGMYREAEKQFKSALK-QQEMVDTFLYLAKVYVSLDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNMS 325
Cdd:COG0457   14 LGLAYRRLGRYEEAIEDYEKALElDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYE 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767979724 326 SAAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEIALRFYRRLLQMGIYNGQLFNNLGLCCFYAQQYDMTLTSFERALSL 405
Cdd:COG0457   94 EALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAA 173

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 767979724 406 AENEEEAADVWYNLGHVAVGIGDTNLAHQCFRLALVNNNNHAEAYNNLAVLEMRKGHVEQIGDLQRSYVAAQ 477
Cdd:COG0457  174 ALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLALRLAALALYQYRA 245
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 277-499 1.06e-16

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 80.16  E-value: 1.06e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767979724 277 FLYLAKVYVSLDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNMSSAAEYYKEVLKQDNTHVEAIACIGSNHFYSD 356
Cdd:COG2956   11 WYFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAG 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767979724 357 QPEIALRFYRRLLQMGIYNGQLFNNLGLCCFYAQQYDMTLTSFERALSLAENEeeaADVWYNLGHVAVGIGDTNLAHQCF 436
Cdd:COG2956   91 LLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPEN---AHAYCELAELYLEQGDYDEAIEAL 167

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767979724 437 RLALVNNNNHAEAYNNLAVLEMRKGHVEQigdlqrSYVAAQKSEAAFPDHVDTQHLIKQLRQH 499
Cdd:COG2956  168 EKALKLDPDCARALLLLAELYLEQGDYEE------AIAALERALEQDPDYLPALPRLAELYEK 224
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 245-440 2.57e-16

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 79.00  E-value: 2.57e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767979724 245 VQIGKCYYRLGMYREAEKQFKSALKQQEM-VDTFLYLAKVYVSLDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNN 323
Cdd:COG2956   80 LELAQDYLKAGLLDRAEELLEKLLELDPDdAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGD 159

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767979724 324 MSSAAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEIALRFYRRLLQMGIYNGQLFNNLGLCCFYAQQYDMTLTSFERAL 403
Cdd:COG2956  160 YDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKAL 239

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 767979724 404 SLAENeeeaADVWYNLGHVAVGIGDTNLAHQCFRLAL 440
Cdd:COG2956  240 ELDPS----DDLLLALADLLERKEGLEAALALLERQL 272
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 271-409 2.47e-14

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 69.84  E-value: 2.47e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767979724 271 QEMVDTFLYLAKVYVSLDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNMSSAAEYYKEVLKQDNTHVEAIACIGS 350
Cdd:COG4783    1 AACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGL 80

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 767979724 351 NHFYSDQPEIALRFYRRLLQMGIYNGQLFNNLGLCCFYAQQYDMTLTSFERALSLAENE 409
Cdd:COG4783   81 ALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 246-371 2.47e-14

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 69.84  E-value: 2.47e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767979724 246 QIGKCYYRLGMYREAEKQFKSALKQQ-EMVDTFLYLAKVYVSLDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNM 324
Cdd:COG4783    9 ALAQALLLAGDYDEAEALLEKALELDpDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDY 88

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 767979724 325 SSAAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEIALRFYRRLLQM 371
Cdd:COG4783   89 DEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALEL 135
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 310-501 6.49e-13

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 71.18  E-value: 6.49e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767979724 310 LLCGIARIYEEMNNMSSAAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEIALRFYRRLLQMGIYNGQLFNNLGLCCFYA 389
Cdd:COG3914   80 LLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRL 159

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767979724 390 QQYDMTLTSFERALSLAENEEEAadvWYNLGHVAVGIGDTNLAHQCFRLALVNNNNHAEAYNNLAVLEMRKGHVEQIGDL 469
Cdd:COG3914  160 GRLEEAIAALRRALELDPDNAEA---LNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNLLFALRQACDWEVYDRF 236

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 767979724 470 QRSYVAAQKSEAAFP------DHVDTQHLIKQLRQHFA 501
Cdd:COG3914  237 EELLAALARGPSELSpfallyLPDDDPAELLALARAWA 274
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
335-465 1.04e-12

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 67.72  E-value: 1.04e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767979724 335 LKQDNTHVEAIACIGSNHFYSDQPEIALRFYRRLLQMGIYNGQLFNNLGLCCFYAQQYDMTLTSFERALSLaenEEEAAD 414
Cdd:COG0457    1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALEL---DPDDAE 77

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 767979724 415 VWYNLGHVAVGIGDTNLAHQCFRLALVNNNNHAEAYNNLAVLEMRKGHVEQ 465
Cdd:COG0457   78 ALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDE 128
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 348-465 1.34e-12

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 65.21  E-value: 1.34e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767979724 348 IGSNHFYSDQPEIALRFYRRLLQMGIYNGQLFNNLGLCCFYAQQYDMTLTSFERALSLAENEEEAadvWYNLGHVAVGIG 427
Cdd:COG4783   10 LAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEA---RLNLGLALLKAG 86

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 767979724 428 DTNLAHQCFRLALVNNNNHAEAYNNLAVLEMRKGHVEQ 465
Cdd:COG4783   87 DYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDE 124
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
246-370 4.74e-12

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 65.80  E-value: 4.74e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767979724 246 QIGKCYYRLGMYREAEKQFKSALKQQ-EMVDTFLYLAKVYVSLDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNM 324
Cdd:COG0457   47 NLGLAYLRLGRYEEALADYEQALELDpDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRY 126

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 767979724 325 SSAAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEIALRFYRRLLQ 370
Cdd:COG0457  127 DEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEA 172
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 228-370 8.07e-11

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 62.82  E-value: 8.07e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767979724 228 LAALSTEHSQYKdwwwkVQIGKCYYRLGMYREAEKQFKSALKQQ-EMVDTFLYLAKVYVSLDQPVTALNLFKQGLDKFPG 306
Cdd:COG2956  136 LLKLGPENAHAY-----CELAELYLEQGDYDEAIEALEKALKLDpDCARALLLLAELYLEQGDYEEAIAALERALEQDPD 210

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767979724 307 EVTLLCGIARIYEEMNNMSSAAEYYKEVLKQDNTHVEAIAcIGSNHFYSDQPEIALRFYRRLLQ 370
Cdd:COG2956  211 YLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLLLA-LADLLERKEGLEAALALLERQLR 273
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 314-446 9.99e-11

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 59.82  E-value: 9.99e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767979724 314 IARIYEEMNNMSSAAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEIALRFYRRLLQMGIYNGQLFNNLGLCCFYAQQYD 393
Cdd:COG4783   10 LAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYD 89

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 767979724 394 MTLTSFERALSLAENEeeaADVWYNLGHVAVGIGDTNLAHQCFRLALVNNNNH 446
Cdd:COG4783   90 EALALLEKALKLDPEH---PEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 259-371 1.14e-10

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 59.25  E-value: 1.14e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767979724 259 EAEKQFKSALKQQ-EMVDTFLYLAKVYVSLDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNMSSAAEYYKEVLKQ 337
Cdd:COG4235    1 EAIARLRQALAANpNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80

                         90       100       110
                 ....*....|....*....|....*....|....
gi 767979724 338 DNTHVEAIACIGSNHFYSDQPEIALRFYRRLLQM 371
Cdd:COG4235   81 DPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLAL 114
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 293-415 9.02e-10

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 56.55  E-value: 9.02e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767979724 293 ALNLFKQGLDKFPGEVTLLCGIARIYEEMNNMSSAAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEIALRFYRRLLQMG 372
Cdd:COG4235    2 AIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALD 81

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 767979724 373 IYNGQLFNNLGLCCFYAQQYDMTLTSFERALSLAENEEEAADV 415
Cdd:COG4235   82 PDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAPARLL 124
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 247-344 4.81e-09

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 58.85  E-value: 4.81e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767979724 247 IGKCYYRLGMYREAEKQFKSALKQQ-EMVDTFLYLAKVYVSLDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNMS 325
Cdd:COG3914  118 LGNLLLALGRLEEALAALRRALALNpDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLE 197

                         90
                 ....*....|....*....
gi 767979724 326 SAAEYYKEVLKQDNTHVEA 344
Cdd:COG3914  198 EAIAAYRRALELDPDNADA 216
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
250-338 1.07e-08

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 52.48  E-value: 1.07e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767979724 250 CYYRLGMYREAEKQFKSALKQQ-EMVDTFLYLAKVYVSLDQPVTALNlFKQGLDKFPGEVTLLCGIARIYEEMNNMSSAA 328
Cdd:COG3063    1 LYLKLGDLEEAEEYYEKALELDpDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEAL 79

                         90
                 ....*....|
gi 767979724 329 EYYKEVLKQD 338
Cdd:COG3063   80 AYLERALELD 89
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 239-346 1.64e-08

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 53.09  E-value: 1.64e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767979724 239 KDWWWKVQIGKCYYRLGMYREAEKQFKSALK-QQEMVDTFLYLAKVYVSLDQPVTALNLFKQGLDKFPGEVTLLCGIARI 317
Cdd:COG4235   15 NDAEGWLLLGRAYLRLGRYDEALAAYEKALRlDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLA 94

                         90       100
                 ....*....|....*....|....*....
gi 767979724 318 YEEMNNMSSAAEYYKEVLKQDNTHVEAIA 346
Cdd:COG4235   95 AFQQGDYAEAIAAWQKLLALLPADAPARL 123
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 239-338 1.99e-08

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 52.89  E-value: 1.99e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767979724 239 KDWWWKVQIGKCYYRLGMYREAEKQFKSALKQQEM-VDTFLYLAKVYVSLDQPVTALNLFKQGLDKFPGEVTLLCGIARI 317
Cdd:COG4783   36 DNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDePEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARA 115

                         90       100
                 ....*....|....*....|.
gi 767979724 318 YEEMNNMSSAAEYYKEVLKQD 338
Cdd:COG4783  116 YRALGRPDEAIAALEKALELD 136
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 375-471 1.02e-07

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 50.77  E-value: 1.02e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767979724 375 NGQLFNNLGLCCFYAQQYDMTLTSFERALSLAENEeeaADVWYNLGHVAVGIGDTNLAHQCFRLALVNNNNHAEAYNNLA 454
Cdd:COG4235   16 DAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDN---ADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLG 92

                         90
                 ....*....|....*...
gi 767979724 455 VLEMRKGHVEQ-IGDLQR 471
Cdd:COG4235   93 LAAFQQGDYAEaIAAWQK 110
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 249-337 1.61e-07

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 49.60  E-value: 1.61e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767979724 249 KCYYRLGMYREAEKQFKSALKQ----QEMVDTFLYLAKVYVSLDQPVTALNLFKQGLDKFPGEVTL---LCGIARIYEEM 321
Cdd:COG1729    1 KALLKAGDYDEAIAAFKAFLKRypnsPLAPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKApdaLLKLGLSYLEL 80

                         90
                 ....*....|....*.
gi 767979724 322 NNMSSAAEYYKEVLKQ 337
Cdd:COG1729   81 GDYDKARATLEELIKK 96
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 218-476 2.15e-07

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 53.55  E-value: 2.15e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767979724  218 KNHIEKNALDLAAlstehsqykdwwwKVQIGKCYYRLGMYREAEKQFKSALKQQ-EMVDTFLYLAKVYVSLDQPVTAL-- 294
Cdd:TIGR02917  46 KNALQKDPNDAEA-------------RFLLGKIYLALGDYAAAEKELRKALSLGyPKNQVLPLLARAYLLQGKFQQVLde 112

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767979724  295 ---------------------------------NLFKQGLDKFPGEVTLLCGIARIYEEMNNMSSAAEYYKEVLKQDNTH 341
Cdd:TIGR02917 113 lpgktllddegaaellalrglaylglgqlelaqKSYEQALAIDPRSLYAKLGLAQLALAENRFDEARALIDEVLTADPGN 192

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767979724  342 VEAIACIGSNHFYSDQPEIALRFYRRLLQMGIYNGQLFNNLGLCCFYAQQYDMTLTSFERALSLAENEEEAAdvwYNLGH 421
Cdd:TIGR02917 193 VDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATILIEAGEFEEAEKHADALLKKAPNSPLAH---YLKAL 269

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 767979724  422 VAVGIGDTNLAHQCFRLALVNNNNHAEAYNNLAVLEMRKGHVEQIGDLQRSYVAA 476
Cdd:TIGR02917 270 VDFQKKNYEDARETLQDALKSAPEYLPALLLAGASEYQLGNLEQAYQYLNQILKY 324
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 249-440 4.61e-07

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 51.83  E-value: 4.61e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767979724 249 KCYYRLGMYREAEKQFKSALKQQEMVDTFL--YLAKVYV-SLDQPVTALNLFKQGLDKFPGE----VTLLCGIARIYEEM 321
Cdd:COG3071  127 QAYRQLGDWEELLELLPALRKHKALSAEEAqaLERRAYLgLLRQAARDAEALKALWKALPRAerrdPELAAAYARALIAL 206

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767979724 322 NNMSSAAEYYKEVLKQdNTHVEAIACIGSNHfySDQPEIALRFYRRLLQMGIYNGQLFNNLGLCCFYAQQYDMTLTSFER 401
Cdd:COG3071  207 GDHDEAERLLREALKR-QWDPRLVRLYGRLQ--GGDPAKQLKRAEKWLKKHPNDPDLLLALGRLCLRNQLWGKAREYLEA 283

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 767979724 402 ALSLAENeeeaADVWYNLGHVAVGIGDTNLAHQCFRLAL 440
Cdd:COG3071  284 ALALRPS----AEAYAELARLLEQLGDPEEAAEHYRKAL 318
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 165-489 5.31e-07

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 52.39  E-value: 5.31e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767979724  165 INLSRLNLTKysQKPKLAKALFEYIF-HHENDVKTI-----------HLEDVVLHLG---------IYPFLLRNKNHIEK 223
Cdd:TIGR02917 503 ANLARIDIQE--GNPDDAIQRFEKVLtIDPKNLRAIlalaglylrtgNEEEAVAWLEkaaelnpqeIEPALALAQYYLGK 580

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767979724  224 NALDLAALSTEHSQ--YKDwwwKVQI----GKCYYRLGMYREAEKQFKSALKQQ-EMVDTFLYLAKVYVSLDQPVTALNL 296
Cdd:TIGR02917 581 GQLKKALAILNEAAdaAPD---SPEAwlmlGRAQLAAGDLNKAVSSFKKLLALQpDSALALLLLADAYAVMKNYAKAITS 657

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767979724  297 FKQGLDKFPGEVTLLCGIARIYEEMNNMSSAAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEIALRFYRRLLQmgiyng 376
Cdd:TIGR02917 658 LKRALELKPDNTEAQIGLAQLLLAAKRTESAKKIAKSLQKQHPKAALGFELEGDLYLRQKDYPAAIQAYRKALK------ 731

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767979724  377 qlfnnlglccfyAQQYDMTLTSFERALSLAENEEEAADV---W-----------YNLGHVAVGIGDTNLAHQCFRLALVN 442
Cdd:TIGR02917 732 ------------RAPSSQNAIKLHRALLASGNTAEAVKTleaWlkthpndavlrTALAELYLAQKDYDKAIKHYQTVVKK 799

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|....*..
gi 767979724  443 NNNHAEAYNNLAVLEMRKGHVEQIGDLQRSYvaaqKSEAAFPDHVDT 489
Cdd:TIGR02917 800 APDNAVVLNNLAWLYLELKDPRALEYAERAL----KLAPNIPAILDT 842
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 356-465 1.97e-06

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 47.65  E-value: 1.97e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767979724 356 DQPEIALRFYRRLLQMGIYNGQLFNNLGLCCFYAQQYDMTLTSFERALSLAENEeeaADVWYNLGHVAVGIGDTNLAHQC 435
Cdd:COG5010   34 ANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNN---PELYYNLALLYSRSGDKDEAKEY 110

                         90       100       110
                 ....*....|....*....|....*....|
gi 767979724 436 FRLALVNNNNHAEAYNNLAVLEMRKGHVEQ 465
Cdd:COG5010  111 YEKALALSPDNPNAYSNLAALLLSLGQDDE 140
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 382-498 4.45e-06

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 46.34  E-value: 4.45e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767979724 382 LGLCCFYAQQYDMTLTSFERALSLAENEEEAadvWYNLGHVAVGIGDTNLAHQCFRLALVNNNNHAEAYNNLAVLEMRKg 461
Cdd:COG4783   10 LAQALLLAGDYDEAEALLEKALELDPDNPEA---FALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKA- 85

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 767979724 462 hveqiGDLQRSYVAAQKSEAAFPDHVDTQHLIKQLRQ 498
Cdd:COG4783   86 -----GDYDEALALLEKALKLDPEHPEAYLRLARAYR 117
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
389-465 5.44e-06

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 44.78  E-value: 5.44e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 767979724 389 AQQYDMTLTSFERALSLAENEeeaADVWYNLGHVAVGIGDTNLAHQcFRLALVNNNNHAEAYNNLAVLEMRKGHVEQ 465
Cdd:COG3063    5 LGDLEEAEEYYEKALELDPDN---ADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDE 77
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 352-443 8.64e-06

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 45.72  E-value: 8.64e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767979724 352 HFYSDQPEIALRFYRRLLQMGIYNGQLFNNLGLCCFYAQQYDMTLTSFERALSLAENEeeaADVWYNLGHVAVGIGDTNL 431
Cdd:COG5010   64 YNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDN---PNAYSNLAALLLSLGQDDE 140

                         90
                 ....*....|..
gi 767979724 432 AHQCFRLALVNN 443
Cdd:COG5010  141 AKAALQRALGTS 152
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
352-440 8.69e-06

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 44.39  E-value: 8.69e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767979724 352 HFYSDQPEIALRFYRRLLQMGIYNGQLFNNLGLCCFYAQQYDMTLtSFERALSLAENEeeaADVWYNLGHVAVGIGDTNL 431
Cdd:COG3063    2 YLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAI-ALEKALKLDPNN---AEALLNLAELLLELGDYDE 77


                 ....*....
gi 767979724 432 AHQCFRLAL 440
Cdd:COG3063   78 ALAYLERAL 86
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 246-306 1.08e-05

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 44.60  E-value: 1.08e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767979724 246 QIGKCYYRLGMYREAEKQFKSALKQ----QEMVDTFLYLAKVYVSLDQPVTALNLFKQGLDKFPG 306
Cdd:COG1729   35 WLGEAYYALGDYDEAAEAFEKLLKRypdsPKAPDALLKLGLSYLELGDYDKARATLEELIKKYPD 99
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 222-338 1.68e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 44.95  E-value: 1.68e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767979724 222 EKNALDLAALSTEHSQYKDWWWKVQIGKCYYRLGMYREAEKQFKSALKQQ-EMVDTFLYLAKVYVSLDQPVTALNLFKQG 300
Cdd:COG5010   35 NNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDpNNPELYYNLALLYSRSGDKDEAKEYYEKA 114

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 767979724 301 LDKFPGEVTLLCGIARIYEEMNNMSSAAEYYKEVLKQD 338
Cdd:COG5010  115 LALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTS 152
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 245-367 1.76e-05

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 47.30  E-value: 1.76e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767979724 245 VQIGKCYYRLGMYREAEKQFKSALKQQ-EMVDTFLYLAKVYVSLDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNN 323
Cdd:COG3914  150 LNLGEALRRLGRLEEAIAALRRALELDpDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNLLFALRQACD 229

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 767979724 324 mSSAAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEIALRFYRR 367
Cdd:COG3914  230 -WEVYDRFEELLAALARGPSELSPFALLYLPDDDPAELLALARA 272
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
377-473 2.96e-05

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 45.29  E-value: 2.96e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767979724 377 QLFNNLGLCCFYAQQYDMTLTSFERALSLaenEEEAADVWYNLGHVAVGIGDTNLAHQCFRLALVNNNNHAEAYNNLAVL 456
Cdd:COG4785   74 QLYYERGVAYDSLGDYDLAIADFDQALEL---DPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIA 150

                         90
                 ....*....|....*...
gi 767979724 457 EMRKGHVEQ-IGDLQRSY 473
Cdd:COG4785  151 LYYLGRYELaIADLEKAL 168
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 316-406 4.27e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 43.80  E-value: 4.27e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767979724 316 RIYEEMNNMSSAAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEIALRFYRRLLQMGIYNGQLFNNLGLCCFYAQQYDMT 395
Cdd:COG5010   62 NLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEA 141

                         90
                 ....*....|.
gi 767979724 396 LTSFERALSLA 406
Cdd:COG5010  142 KAALQRALGTS 152
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 245-455 4.40e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 46.23  E-value: 4.40e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767979724  245 VQIGKCYYRLGMYREAEKQFKSALKQQE-MVDTFLYLAKVYVSLDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNN 323
Cdd:TIGR02917 639 LLLADAYAVMKNYAKAITSLKRALELKPdNTEAQIGLAQLLLAAKRTESAKKIAKSLQKQHPKAALGFELEGDLYLRQKD 718

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767979724  324 MSSAAEYYKEVLKQDNTHVEAI----ACIGS----------NHFYSDQPE-IALRF------------------YRRLLQ 370
Cdd:TIGR02917 719 YPAAIQAYRKALKRAPSSQNAIklhrALLASgntaeavktlEAWLKTHPNdAVLRTalaelylaqkdydkaikhYQTVVK 798

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767979724  371 MGIYNGQLFNNLGLccFYAQQYD-MTLTSFERALSLAENEEEAADVwynLGHVAVGIGDTNLAHQCFRLALVNNNNHAEA 449
Cdd:TIGR02917 799 KAPDNAVVLNNLAW--LYLELKDpRALEYAERALKLAPNIPAILDT---LGWLLVEKGEADRALPLLRKAVNIAPEAAAI 873


                  ....*.
gi 767979724  450 YNNLAV 455
Cdd:TIGR02917 874 RYHLAL 879
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 257-370 9.59e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 42.64  E-value: 9.59e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767979724 257 YREAEKQFKSALKQQEMVDTFLYLAKVYVSLDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNMSSAAEYYKEVLK 336
Cdd:COG5010   37 TKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALA 116

                         90       100       110
                 ....*....|....*....|....*....|....
gi 767979724 337 QDNTHVEAIACIGSNHFYSDQPEIALRFYRRLLQ 370
Cdd:COG5010  117 LSPDNPNAYSNLAALLLSLGQDDEAKAALQRALG 150
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
317-406 1.04e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 41.31  E-value: 1.04e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767979724 317 IYEEMNNMSSAAEYYKEVLKQDNTHVEAIACIGSNHFYSDQPEIALRFyRRLLQMGIYNGQLFNNLGLCCFYAQQYDMTL 396
Cdd:COG3063    1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIAL-EKALKLDPNNAEALLNLAELLLELGDYDEAL 79

                         90
                 ....*....|
gi 767979724 397 TSFERALSLA 406
Cdd:COG3063   80 AYLERALELD 89
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
361-471 1.18e-04

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 43.37  E-value: 1.18e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767979724 361 ALRFYRRLLQMGIYNGQLFNNLGLCCFYAQQYDMTLTSFERALSLAENeeeAADVWYNLGHVAVGIGDTNLAHQCFRLAL 440
Cdd:COG4785   92 AIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPD---YAYAYLNRGIALYYLGRYELAIADLEKAL 168

                         90       100       110
                 ....*....|....*....|....*....|.
gi 767979724 441 VNNNNHAEAYNNLAVLEMRKGHVEQIGDLQR 471
Cdd:COG4785  169 ELDPNDPERALWLYLAERKLDPEKALALLLE 199
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 239-307 1.79e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 41.72  E-value: 1.79e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767979724 239 KDWWWKVQIGKCYYRLGMYREAEKQFKSALKQQ-EMVDTFLYLAKVYVSLDQPVTALNLFKQGLDKFPGE 307
Cdd:COG4783   70 DEPEARLNLGLALLKAGDYDEALALLEKALKLDpEHPEAYLRLARAYRALGRPDEAIAALEKALELDPDD 139
TPR_12 pfam13424
Tetratricopeptide repeat;
380-440 1.95e-04

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 40.06  E-value: 1.95e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767979724  380 NNLGLCCFYAQQYDMTLTSFERALSLAENE-----EEAADVWYNLGHVAVGIGDTNLAHQCFRLAL 440
Cdd:pfam13424   7 NNLAAVLRRLGRYDEALELLEKALEIARRLlgpdhPLTATTLLNLGRLYLELGRYEEALELLERAL 72
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 248-301 8.43e-04

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 41.43  E-value: 8.43e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 767979724 248 GKCYYRLGMYREAEKQFKSALKQQEMVDTFLYLAKVYVSLDQPVTALNLFKQGL 301
Cdd:COG3071  265 GRLCLRNQLWGKAREYLEAALALRPSAEAYAELARLLEQLGDPEEAAEHYRKAL 318
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 251-496 1.16e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 41.61  E-value: 1.16e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767979724  251 YYRLGMYREAEKQFKSALKQQ-EMVDTFLYLAKVYVSLDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNMSSAAE 329
Cdd:TIGR02917 441 YLRSGQFDKALAAAKKLEKKQpDNASLHNLLGAIYLGKGDLAKAREAFEKALSIEPDFFPAAANLARIDIQEGNPDDAIQ 520

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767979724  330 YYKEVLKQDNTHVEAIACIGSNHFYSDQPEIALRFYRRLlqMGIYNGQLFNNLGLCCFYAQQYDMTLtSFERALSLAENE 409
Cdd:TIGR02917 521 RFEKVLTIDPKNLRAILALAGLYLRTGNEEEAVAWLEKA--AELNPQEIEPALALAQYYLGKGQLKK-ALAILNEAADAA 597

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767979724  410 EEAADVWYNLGHVAVGIGDTNLAHQCFRLALVNNNNHAEAYNNLAVLEMRKGHVEQigdLQRSYvaaQKSEAAFPDHVDT 489
Cdd:TIGR02917 598 PDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAK---AITSL---KRALELKPDNTEA 671


                  ....*..
gi 767979724  490 QHLIKQL 496
Cdd:TIGR02917 672 QIGLAQL 678
LPA1 PLN03098
LOW PSII ACCUMULATION1; Provisional
 381-444 2.72e-03

LOW PSII ACCUMULATION1; Provisional


Pssm-ID: 215573 [Multi-domain]  Cd Length: 453  Bit Score: 40.26  E-value: 2.72e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767979724 381 NLGLCCFYAQQYDMTLTSFERALSLAENEEEAADVWYNLGHVAVGIGDTNLAHQCFRLALVNNN 444
Cdd:PLN03098  80 NLGLSLFSKGRVKDALAQFETALELNPNPDEAQAAYYNKACCHAYREEGKKAADCLRTALRDYN 143
TPR_12 pfam13424
Tetratricopeptide repeat;
245-336 4.92e-03

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 35.83  E-value: 4.92e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767979724  245 VQIGKCYYRLGMYREAEKQFKSALKQQEmvdtflylakvyvsldqpvtalnlfKQGLDKFPGEVTLLCGIARIYEEMNNM 324
Cdd:pfam13424   7 NNLAAVLRRLGRYDEALELLEKALEIAR-------------------------RLLGPDHPLTATTLLNLGRLYLELGRY 61

                          90
                  ....*....|..
gi 767979724  325 SSAAEYYKEVLK 336
Cdd:pfam13424  62 EEALELLERALA 73
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 351-449 6.74e-03

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 36.51  E-value: 6.74e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767979724 351 NHFYSDQPEIALRFYRRLLQM---GIYNGQLFNNLGLCCFYAQQYDMTLTSFERALSLAENEEEAADVWYNLGHVAVGIG 427
Cdd:COG1729    2 ALLKAGDYDEAIAAFKAFLKRypnSPLAPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKAPDALLKLGLSYLELG 81

                         90       100
                 ....*....|....*....|..
gi 767979724 428 DTNLAHQCFRLALVNNNNHAEA 449
Cdd:COG1729   82 DYDKARATLEELIKKYPDSEAA 103
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 247-303 9.19e-03

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 38.17  E-value: 9.19e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 767979724 247 IGKCYYRLGMYREAEKQFKSALKQQEMVDTFLYLAKVYVSLDQPVTALNLFKQGLDK 303
Cdd:COG2956  218 LAELYEKLGDPEEALELLRKALELDPSDDLLLALADLLERKEGLEAALALLERQLRR 274
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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