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Conserved domains on  [gi|767981565|ref|XP_011535478|]
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basal body-orientation factor 1 isoform X7 [Homo sapiens]

Protein Classification

BBOF1/CCDC121 family protein( domain architecture ID 12171747)

BBOF1/CCDC121 family protein is a DUF4515 domain-containing protein; similar to Homo sapiens basal body-orientation factor 1 and coiled-coil domain-containing protein 121

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF4515 pfam14988
Domain of unknown function (DUF4515); This family of proteins is found in bacteria and ...
 4-191 1.36e-55

Domain of unknown function (DUF4515); This family of proteins is found in bacteria and eukaryotes. Proteins in this family are typically between 198 and 469 amino acids in length. There are two completely conserved L residues that may be functionally important.


:

Pssm-ID: 405647 [Multi-domain]  Cd Length: 206  Bit Score: 185.36  E-value: 1.36e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981565    4 DIMSVLSYLKKQDQEKDNMIEKLKQQLNETKEKAQEEKDKLEQKYTRQINELEGQFHQKAKEIGMIHTELKAVRQFQKRK 83
Cdd:pfam14988   1 ENKFFLEYLAKKTEEKQKKIEKLWNQYVQECEEIERRRQELASRYTQQTAELQTQLLQKEKEQASLKKELQALRPFAKLK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981565   84 IQVERELDDLKENLRNTERIHQETLRRLESRFFEEKHRLEQEA-EKKIIMLAERAHHE-----------AIVQLNDAGRN 151
Cdd:pfam14988  81 ESQEREIQDLEEEKEKVRAETAEKDREAHLQFLKEKALLEKQLqELRILELGERATRElkrkaqalklaAKQALSEFCRS 160

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 767981565  152 VFKENDYLQKALAYHLKETDALQKNSQKLQESHTLLLHQK 191
Cdd:pfam14988 161 IKRENRQLQKELLQLIQETQALEAIKSKLENRKQRLKEEQ 200
 
Name Accession Description Interval E-value
DUF4515 pfam14988
Domain of unknown function (DUF4515); This family of proteins is found in bacteria and ...
 4-191 1.36e-55

Domain of unknown function (DUF4515); This family of proteins is found in bacteria and eukaryotes. Proteins in this family are typically between 198 and 469 amino acids in length. There are two completely conserved L residues that may be functionally important.


Pssm-ID: 405647 [Multi-domain]  Cd Length: 206  Bit Score: 185.36  E-value: 1.36e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981565    4 DIMSVLSYLKKQDQEKDNMIEKLKQQLNETKEKAQEEKDKLEQKYTRQINELEGQFHQKAKEIGMIHTELKAVRQFQKRK 83
Cdd:pfam14988   1 ENKFFLEYLAKKTEEKQKKIEKLWNQYVQECEEIERRRQELASRYTQQTAELQTQLLQKEKEQASLKKELQALRPFAKLK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981565   84 IQVERELDDLKENLRNTERIHQETLRRLESRFFEEKHRLEQEA-EKKIIMLAERAHHE-----------AIVQLNDAGRN 151
Cdd:pfam14988  81 ESQEREIQDLEEEKEKVRAETAEKDREAHLQFLKEKALLEKQLqELRILELGERATRElkrkaqalklaAKQALSEFCRS 160

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 767981565  152 VFKENDYLQKALAYHLKETDALQKNSQKLQESHTLLLHQK 191
Cdd:pfam14988 161 IKRENRQLQKELLQLIQETQALEAIKSKLENRKQRLKEEQ 200
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 9-314 2.31e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 50.44  E-value: 2.31e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981565     9 LSYLKKQDQEKDNMIEKLKQQLNETKEKaQEEKDKLEQKYTRQINELEGQFHQKAKEIGMIHTELKAVRQFQKRKIQVER 88
Cdd:TIGR02168  227 LALLVLRLEELREELEELQEELKEAEEE-LEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQ 305

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981565    89 ELDDLKENLRNTERIHQETLRRLESRfFEEKHRLEQEAEKKIIMLAERahHEAIVQLNDAGRNVFKEndylqKALAYHLK 168
Cdd:TIGR02168  306 ILRERLANLERQLEELEAQLEELESK-LDELAEELAELEEKLEELKEE--LESLEAELEELEAELEE-----LESRLEEL 377

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981565   169 ETDALQKNSQKLQESHTLLLHQKswSLSHLGIHLAVSNSpdisgiTTQGFILSPKGGLEEINDLLVKEKIMQLVQQRSQI 248
Cdd:TIGR02168  378 EEQLETLRSKVAQLELQIASLNN--EIERLEARLERLED------RRERLQQEIEELLKKLEEAELKELQAELEELEEEL 449

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767981565   249 QTLQKKVVNLETALSYMTKEFESEVLKLQQHAMIENQAGQvEIDKLQHLLQMKDREMNRVKKLAKN 314
Cdd:TIGR02168  450 EELQEELERLEEALEELREELEEAEQALDAAERELAQLQA-RLDSLERLQENLEGFSEGVKALLKN 514
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 9-182 4.65e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 43.00  E-value: 4.65e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981565   9 LSYLKKQDQEKDNMIEKLKQQLNETKEKAQEEKDKLEQKyTRQINELEGQFHQKAKEIGMIHTELKAVRQfqkRKIQVER 88
Cdd:COG1196  241 LEELEAELEELEAELEELEAELAELEAELEELRLELEEL-ELELEEAQAEEYELLAELARLEQDIARLEE---RRRELEE 316

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981565  89 ELDDLKENLRNTERiHQETLRRLESRFFEEKHRLEQEAEKKIIMLAE------RAHHEAIVQLNDAGRNVFKENDYLQKA 162
Cdd:COG1196  317 RLEELEEELAELEE-ELEELEEELEELEEELEEAEEELEEAEAELAEaeeallEAEAELAEAEEELEELAEELLEALRAA 395

                        170       180
                 ....*....|....*....|
gi 767981565 163 LAYHLKETDALQKNSQKLQE 182
Cdd:COG1196  396 AELAAQLEELEEAEEALLER 415
PRK12704 PRK12704
phosphodiesterase; Provisional
 16-141 2.89e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 40.15  E-value: 2.89e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981565  16 DQEKDNMIEKLKQQLNETKEKAQEEKDKLEQKYTRQINELEGQFHQKAKEIGMIHTELKAV----RQFQKRKIQVERELD 91
Cdd:PRK12704  45 EEAKKEAEAIKKEALLEAKEEIHKLRNEFEKELRERRNELQKLEKRLLQKEENLDRKLELLekreEELEKKEKELEQKQQ 124

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 767981565  92 DLKENLRNTERIHQETLRRLE--SRFFEEKHR------LEQEAEKKIIMLAERAHHEA 141
Cdd:PRK12704 125 ELEKKEEELEELIEEQLQELEriSGLTAEEAKeillekVEEEARHEAAVLIKEIEEEA 182
 
Name Accession Description Interval E-value
DUF4515 pfam14988
Domain of unknown function (DUF4515); This family of proteins is found in bacteria and ...
 4-191 1.36e-55

Domain of unknown function (DUF4515); This family of proteins is found in bacteria and eukaryotes. Proteins in this family are typically between 198 and 469 amino acids in length. There are two completely conserved L residues that may be functionally important.


Pssm-ID: 405647 [Multi-domain]  Cd Length: 206  Bit Score: 185.36  E-value: 1.36e-55
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981565    4 DIMSVLSYLKKQDQEKDNMIEKLKQQLNETKEKAQEEKDKLEQKYTRQINELEGQFHQKAKEIGMIHTELKAVRQFQKRK 83
Cdd:pfam14988   1 ENKFFLEYLAKKTEEKQKKIEKLWNQYVQECEEIERRRQELASRYTQQTAELQTQLLQKEKEQASLKKELQALRPFAKLK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981565   84 IQVERELDDLKENLRNTERIHQETLRRLESRFFEEKHRLEQEA-EKKIIMLAERAHHE-----------AIVQLNDAGRN 151
Cdd:pfam14988  81 ESQEREIQDLEEEKEKVRAETAEKDREAHLQFLKEKALLEKQLqELRILELGERATRElkrkaqalklaAKQALSEFCRS 160

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 767981565  152 VFKENDYLQKALAYHLKETDALQKNSQKLQESHTLLLHQK 191
Cdd:pfam14988 161 IKRENRQLQKELLQLIQETQALEAIKSKLENRKQRLKEEQ 200
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 9-314 2.31e-06

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 50.44  E-value: 2.31e-06
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981565     9 LSYLKKQDQEKDNMIEKLKQQLNETKEKaQEEKDKLEQKYTRQINELEGQFHQKAKEIGMIHTELKAVRQFQKRKIQVER 88
Cdd:TIGR02168  227 LALLVLRLEELREELEELQEELKEAEEE-LEELTAELQELEEKLEELRLEVSELEEEIEELQKELYALANEISRLEQQKQ 305

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981565    89 ELDDLKENLRNTERIHQETLRRLESRfFEEKHRLEQEAEKKIIMLAERahHEAIVQLNDAGRNVFKEndylqKALAYHLK 168
Cdd:TIGR02168  306 ILRERLANLERQLEELEAQLEELESK-LDELAEELAELEEKLEELKEE--LESLEAELEELEAELEE-----LESRLEEL 377

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981565   169 ETDALQKNSQKLQESHTLLLHQKswSLSHLGIHLAVSNSpdisgiTTQGFILSPKGGLEEINDLLVKEKIMQLVQQRSQI 248
Cdd:TIGR02168  378 EEQLETLRSKVAQLELQIASLNN--EIERLEARLERLED------RRERLQQEIEELLKKLEEAELKELQAELEELEEEL 449

                          250       260       270       280       290       300
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 767981565   249 QTLQKKVVNLETALSYMTKEFESEVLKLQQHAMIENQAGQvEIDKLQHLLQMKDREMNRVKKLAKN 314
Cdd:TIGR02168  450 EELQEELERLEEALEELREELEEAEQALDAAERELAQLQA-RLDSLERLQENLEGFSEGVKALLKN 514
CCDC158 pfam15921
Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. ...
 12-302 1.51e-04

Coiled-coil domain-containing protein 158; CCDC158 is a family of proteins found in eukaryotes. The function is not known.


Pssm-ID: 464943 [Multi-domain]  Cd Length: 1112  Bit Score: 44.72  E-value: 1.51e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981565    12 LKKQDQEKDNMIEKLKQQL-NETK--------------EKAQEEKD------------KLEQKYTRQINELEGQFH---- 60
Cdd:pfam15921  553 LKLQMAEKDKVIEILRQQIeNMTQlvgqhgrtagamqvEKAQLEKEindrrlelqefkILKDKKDAKIRELEARVSdlel 632

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981565    61 QKAKEIGMIHTELKAVRQFQKRKIQVERELDD--------------LKENLRNTERIHQETLRRLESRFFEEKHRLEQEA 126
Cdd:pfam15921  633 EKVKLVNAGSERLRAVKDIKQERDQLLNEVKTsrnelnslsedyevLKRNFRNKSEEMETTTNKLKMQLKSAQSELEQTR 712

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981565   127 EKKIIMLAERAHheaivqlndagrnVFKENDYLQKALAYHLKETDALQKNSQKLQESHTLLLHQKswslsHLGIHLAVSN 206
Cdd:pfam15921  713 NTLKSMEGSDGH-------------AMKVAMGMQKQITAKRGQIDALQSKIQFLEEAMTNANKEK-----HFLKEEKNKL 774

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981565   207 SPDISGITTQGFILSpkGGLEEIndllvkekimqlvqqRSQIQTLQKKVVNLETALSYMTKEFEsevlklQQHAMIENQA 286
Cdd:pfam15921  775 SQELSTVATEKNKMA--GELEVL---------------RSQERRLKEKVANMEVALDKASLQFA------ECQDIIQRQE 831

                          330
                   ....*....|....*.
gi 767981565   287 GQVEIDKLQHLLQMKD 302
Cdd:pfam15921  832 QESVRLKLQHTLDVKE 847
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 9-182 4.65e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 43.00  E-value: 4.65e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981565   9 LSYLKKQDQEKDNMIEKLKQQLNETKEKAQEEKDKLEQKyTRQINELEGQFHQKAKEIGMIHTELKAVRQfqkRKIQVER 88
Cdd:COG1196  241 LEELEAELEELEAELEELEAELAELEAELEELRLELEEL-ELELEEAQAEEYELLAELARLEQDIARLEE---RRRELEE 316

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981565  89 ELDDLKENLRNTERiHQETLRRLESRFFEEKHRLEQEAEKKIIMLAE------RAHHEAIVQLNDAGRNVFKENDYLQKA 162
Cdd:COG1196  317 RLEELEEELAELEE-ELEELEEELEELEEELEEAEEELEEAEAELAEaeeallEAEAELAEAEEELEELAEELLEALRAA 395

                        170       180
                 ....*....|....*....|
gi 767981565 163 LAYHLKETDALQKNSQKLQE 182
Cdd:COG1196  396 AELAAQLEELEEAEEALLER 415
DUF4618 pfam15397
Domain of unknown function (DUF4618); This family of proteins is found in eukaryotes. Proteins ...
 3-183 5.34e-04

Domain of unknown function (DUF4618); This family of proteins is found in eukaryotes. Proteins in this family are typically between 238 and 363 amino acids in length. There are two conserved sequence motifs: EYP and KCTPD.


Pssm-ID: 464704 [Multi-domain]  Cd Length: 258  Bit Score: 41.86  E-value: 5.34e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981565    3 KDIMSVLSYLKKqdqekdNMIEKLKQQLNETKEKAQEEKDKLEQkytrQINELEGQFHQKAKEIGMIHT------ELKAV 76
Cdd:pfam15397  51 GTIISILEYSNK------KQLQQAKAELQEWEEKEESKLNKLEQ----QLEQLNAKIQKTQEELNFLSTykdkeyPVKAV 120

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981565   77 ------RQFQKRKIQVERELDDLkenlrntERIHQETLRRLESRFFEEKHRLEQEAEKKIIMlaerAHHEAIVQLNDAGR 150
Cdd:pfam15397 121 qianlvRQLQQLKDSQQDELDEL-------EEMRRMVLESLSRKIQKKKEKILSSLAEKTLS----PYQESLLQKTRDNQ 189

                         170       180       190
                  ....*....|....*....|....*....|...
gi 767981565  151 NVFKENDYLQKALAYHLKETDALQKNSQKLQES 183
Cdd:pfam15397 190 VMLKEIEQFREFIDELEEEIPKLKAEVQQLQAQ 222
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 12-191 6.49e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 42.62  E-value: 6.49e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981565  12 LKKQDQEKDNMIEKLKQQLNETKEKAQEEKDKLEQkYTRQINELEGQFHQKAKEIgmiHTELKAVRQFQKRKIQVERELD 91
Cdd:COG1196  286 AQAEEYELLAELARLEQDIARLEERRRELEERLEE-LEEELAELEEELEELEEEL---EELEEELEEAEEELEEAEAELA 361

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981565  92 DLKENLRNTERIHQETLRRLESRFFEEKHRLEQEAEKKIIMLAERAHHEAIVQ-LNDAGRNVFKENDYLQKALAYHLKET 170
Cdd:COG1196  362 EAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLErLERLEEELEELEEALAELEEEEEEEE 441

                        170       180
                 ....*....|....*....|.
gi 767981565 171 DALQKNSQKLQESHTLLLHQK 191
Cdd:COG1196  442 EALEEAAEEEAELEEEEEALL 462
DUF5401 pfam17380
Family of unknown function (DUF5401); This is a family of unknown function found in ...
 1-163 2.00e-03

Family of unknown function (DUF5401); This is a family of unknown function found in Chromadorea.


Pssm-ID: 375164 [Multi-domain]  Cd Length: 722  Bit Score: 40.88  E-value: 2.00e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981565    1 MEKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETKEKAQE-EKDKLEQKYTRQINELEGQFHQKAKEIGMIHTElkavrqf 79
Cdd:pfam17380 440 LEEERAREMERVRLEEQERQQQVERLRQQEEERKRKKLElEKEKRDRKRAEEQRRKILEKELEERKQAMIEEE------- 512

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981565   80 QKRKIqVERELDDLKENLRNTERIHQETLRRLESRFFEEKHRLEQEAEKkiiMLAERAHHEAIVQLNDAGRNVfKENDYL 159
Cdd:pfam17380 513 RKRKL-LEKEMEERQKAIYEEERRREAEEERRKQQEMEERRRIQEQMRK---ATEERSRLEAMEREREMMRQI-VESEKA 587


                  ....
gi 767981565  160 QKAL 163
Cdd:pfam17380 588 RAEY 591
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 9-190 2.27e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 40.69  E-value: 2.27e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981565   9 LSYLKKQDQEKDNMIEKLKQQLNETKEKAQEEKDKLEQKyTRQINELEGQFHQKAKEIgmiHTELKAVRQFQKRKIQVER 88
Cdd:COG1196  304 IARLEERRRELEERLEELEEELAELEEELEELEEELEEL-EEELEEAEEELEEAEAEL---AEAEEALLEAEAELAEAEE 379

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981565  89 ELDDLKENLRNTERIHQETLRRLESRFFEEKHRLEQEAEKKIIMLAERAHHEAIVQLNDAGRNVFKEndyLQKALAYHLK 168
Cdd:COG1196  380 ELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEE---AAEEEAELEE 456

                        170       180
                 ....*....|....*....|..
gi 767981565 169 ETDALQKNSQKLQESHTLLLHQ 190
Cdd:COG1196  457 EEEALLELLAELLEEAALLEAA 478
PRK12704 PRK12704
phosphodiesterase; Provisional
 16-141 2.89e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 40.15  E-value: 2.89e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981565  16 DQEKDNMIEKLKQQLNETKEKAQEEKDKLEQKYTRQINELEGQFHQKAKEIGMIHTELKAV----RQFQKRKIQVERELD 91
Cdd:PRK12704  45 EEAKKEAEAIKKEALLEAKEEIHKLRNEFEKELRERRNELQKLEKRLLQKEENLDRKLELLekreEELEKKEKELEQKQQ 124

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 767981565  92 DLKENLRNTERIHQETLRRLE--SRFFEEKHR------LEQEAEKKIIMLAERAHHEA 141
Cdd:PRK12704 125 ELEKKEEELEELIEEQLQELEriSGLTAEEAKeillekVEEEARHEAAVLIKEIEEEA 182
PTZ00121 PTZ00121
MAEBL; Provisional
 12-99 3.15e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 40.51  E-value: 3.15e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981565   12 LKKQDQEKDNMIEKLKQQLNETKEKAQEEKDKLEQKytRQINELEGQFHQKAKEI-----GMIHTELKavRQFQKRKIQV 86
Cdd:PTZ00121 1721 LKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEK--KKIAHLKKEEEKKAEEIrkekeAVIEEELD--EEDEKRRMEV 1796

                          90
                  ....*....|...
gi 767981565   87 ERELDDLKENLRN 99
Cdd:PTZ00121 1797 DKKIKDIFDNFAN 1809
CALCOCO1 pfam07888
Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are ...
 1-126 3.74e-03

Calcium binding and coiled-coil domain (CALCOCO1) like; Proteins found in this family are similar to the coiled-coil transcriptional coactivator protein coexpressed by Mus musculus (CoCoA/CALCOCO1). This protein binds to a highly conserved N-terminal domain of p160 coactivators, such as GRIP1, and thus enhances transcriptional activation by a number of nuclear receptors. CALCOCO1 has a central coiled-coil region with three leucine zipper motifs, which is required for its interaction with GRIP1 and may regulate the autonomous transcriptional activation activity of the C-terminal region.


Pssm-ID: 462303 [Multi-domain]  Cd Length: 488  Bit Score: 39.88  E-value: 3.74e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981565    1 MEKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETKEKAQEEKDKLEQKYTRQ--INELEGQFHQKAKEIGMIHTELKAVRQ 78
Cdd:pfam07888  78 LESRVAELKEELRQSREKHEELEEKYKELSASSEELSEEKDALLAQRAAHEarIRELEEDIKTLTQRVLERETELERMKE 157

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 767981565   79 FQKRKIQVERELDDLKENLRNTERIHQETLRRLESRFFEEKHRLEQEA 126
Cdd:pfam07888 158 RAKKAGAQRKEEEAERKQLQAKLQQTEEELRSLSKEFQELRNSLAQRD 205
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 6-102 4.81e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 39.36  E-value: 4.81e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981565   6 MSVLSYLKKQDQEKDNMIEKLKQQLNETKEKAQEEKDKLEQKYTR---QINELEGQFHQKAKEIGMIHTELKAVRQFQKR 82
Cdd:COG4942  138 LQYLKYLAPARREQAEELRADLAELAALRAELEAERAELEALLAEleeERAALEALKAERQKLLARLEKELAELAAELAE 217

                         90       100
                 ....*....|....*....|
gi 767981565  83 KIQVERELDDLKENLRNTER 102
Cdd:COG4942  218 LQQEAEELEALIARLEAEAA 237
PRK12704 PRK12704
phosphodiesterase; Provisional
 11-147 5.02e-03

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 39.38  E-value: 5.02e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981565  11 YLKKQDQEK-DNMIEKLKQQLNETKEKAQEEKDKLE----QKYTRQINELEGQFHQKAKEIGMIHTELKAVRQFQKRKIQ 85
Cdd:PRK12704  24 VRKKIAEAKiKEAEEEAKRILEEAKKEAEAIKKEALleakEEIHKLRNEFEKELRERRNELQKLEKRLLQKEENLDRKLE 103

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 767981565  86 V----ERELDDLKENLRNTERIHQETLRRLESRFFEEKHRLE------QEAEKKIIM--LAERAHHEAIVQLND 147
Cdd:PRK12704 104 LlekrEEELEKKEKELEQKQQELEKKEEELEELIEEQLQELErisgltAEEAKEILLekVEEEARHEAAVLIKE 177
PTZ00121 PTZ00121
MAEBL; Provisional
 2-155 8.41e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 38.97  E-value: 8.41e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981565    2 EKDIMSVLSYLKKQDQEKDNMIEKLKQQLNETKEKAQEEKDKLEQ--KYTRQINELEGQFHQKAKEIGMIHTELKAVRQF 79
Cdd:PTZ00121 1628 AEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEdkKKAEEAKKAEEDEKKAAEALKKEAEEAKKAEEL 1707

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767981565   80 QKRKIQVERElddlKENLRNTERIHQETLRRLESRFFEEKHRLEQ----EAEKKIIMLAERAHHEAIVQLNDAGRNVFKE 155
Cdd:PTZ00121 1708 KKKEAEEKKK----AEELKKAEEENKIKAEEAKKEAEEDKKKAEEakkdEEEKKKIAHLKKEEEKKAEEIRKEKEAVIEE 1783
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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