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Conserved domains on  [gi|767973549|ref|XP_011536362|]
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nuclear envelope integral membrane protein 1 isoform X5 [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
NEMP super family cl10912
NEMP family; This entry includes a group of nuclear envelope integral membrane proteins from ...
 202-261 3.10e-23

NEMP family; This entry includes a group of nuclear envelope integral membrane proteins from animals and plants, including NEMP1 from Xenopus laevis. NEMP1 is a RanGTP-binding protein and is involved in eye development.


The actual alignment was detected with superfamily member pfam10225:

Pssm-ID: 463008  Cd Length: 249  Bit Score: 94.97  E-value: 3.10e-23
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 767973549  202 IVIRRFDPKLFLVFLLGLMLFFCGDLLSRSQIFYYSTGMTVGIVASLLIIIFILSKFMPK 261
Cdd:pfam10225   4 LEEERFDFWRLLVFLLGILLFLLAPTLSRSVVFYYSSGMSLGILASLLILLFQLSKLLPK 63
 
Name Accession Description Interval E-value
NEMP pfam10225
NEMP family; This entry includes a group of nuclear envelope integral membrane proteins from ...
 202-261 3.10e-23

NEMP family; This entry includes a group of nuclear envelope integral membrane proteins from animals and plants, including NEMP1 from Xenopus laevis. NEMP1 is a RanGTP-binding protein and is involved in eye development.


Pssm-ID: 463008  Cd Length: 249  Bit Score: 94.97  E-value: 3.10e-23
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 767973549  202 IVIRRFDPKLFLVFLLGLMLFFCGDLLSRSQIFYYSTGMTVGIVASLLIIIFILSKFMPK 261
Cdd:pfam10225   4 LEEERFDFWRLLVFLLGILLFLLAPTLSRSVVFYYSSGMSLGILASLLILLFQLSKLLPK 63
 
Name Accession Description Interval E-value
NEMP pfam10225
NEMP family; This entry includes a group of nuclear envelope integral membrane proteins from ...
 202-261 3.10e-23

NEMP family; This entry includes a group of nuclear envelope integral membrane proteins from animals and plants, including NEMP1 from Xenopus laevis. NEMP1 is a RanGTP-binding protein and is involved in eye development.


Pssm-ID: 463008  Cd Length: 249  Bit Score: 94.97  E-value: 3.10e-23
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 767973549  202 IVIRRFDPKLFLVFLLGLMLFFCGDLLSRSQIFYYSTGMTVGIVASLLIIIFILSKFMPK 261
Cdd:pfam10225   4 LEEERFDFWRLLVFLLGILLFLLAPTLSRSVVFYYSSGMSLGILASLLILLFQLSKLLPK 63
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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